Other Species / Isoforms
  MKK3 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

  HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
S3-p
_____MEsPASSQPA
Upstream
0 9
Treatment
  • nocodazole
MKK3 (human) _____MEsPASSQPA S3-p
MKK3 iso2 (human) gap -
MKK3 iso3 (human) gap -
MKK3 (mouse) _____MEsPAAsPPA S3-p
MKK3 (rat) ATVRSMESPAASPPA S75
S7
_MEsPASSQPASMPQ
0 1
MKK3 (human) _MEsPASSQPASMPQ S7
MKK3 iso2 (human) gap -
MKK3 iso3 (human) gap -
MKK3 (mouse) _MEsPAAsPPASLPQ S7-p
MKK3 (rat) SMESPAASPPASLPQ S79
S15-p
QPASMPQsKGKSKRK
Upstream
0 3
Treatment
  • nocodazole
MKK3 (human) QPASMPQsKGKSKRK S15-p
MKK3 iso2 (human) gap -
MKK3 iso3 (human) gap -
MKK3 (mouse) PPASLPQTKGKSKRK T15
MKK3 (rat) PPASLPQTKGKSKRK T87
S28-p
RKKDLRIsCMskPPA
0 2
MKK3 (human) RKKDLRIsCMskPPA S28-p
MKK3 iso2 (human) gap -
MKK3 iso3 (human) RKKDLRISCMSKPPA S33
MKK3 (mouse) RKKDLRIsCVsKPPV S28-p
MKK3 (rat) RKRDLRISCVSKPPV S100
S31-p
DLRIsCMskPPAPNP
0 2
MKK3 (human) DLRIsCMskPPAPNP S31-p
MKK3 iso2 (human) ______MSKPPAPNP S2
MKK3 iso3 (human) DLRISCMSKPPAPNP S36
MKK3 (mouse) DLRIsCVsKPPVSNP S31-p
MKK3 (rat) DLRISCVSKPPVSNP S103
K32-ub
LRIsCMskPPAPNPt
0 3
MKK3 (human) LRIsCMskPPAPNPt K32-ub
MKK3 iso2 (human) _____MSKPPAPNPT K3
MKK3 iso3 (human) LRISCMSKPPAPNPT K37
MKK3 (mouse) LRIsCVsKPPVSNPT K32
MKK3 (rat) LRISCVSKPPVSNPT K104
T39-p
kPPAPNPtPPRNLDS
0 11
MKK3 (human) kPPAPNPtPPRNLDS T39-p
MKK3 iso2 (human) KPPAPNPTPPRNLDS T10
MKK3 iso3 (human) KPPAPNPTPPRNLDS T44
MKK3 (mouse) KPPVSNPTPPRNLDS T39
MKK3 (rat) KPPVSNPTPPRNLDS T111
K80-ub
GAYGVVEkVRHAQSG
0 9
MKK3 (human) GAYGVVEkVRHAQSG K80-ub
MKK3 iso2 (human) GAYGVVEKVRHAQSG K51
MKK3 iso3 (human) GAYGVVEKVRHAQSG K85
MKK3 (mouse) GAYGVVEkVRHAQSG K80-ub
MKK3 (rat) GAYGVVEKVRHAQSG K152
K93-ub
SGTIMAVkRIRATVN
0 1
MKK3 (human) SGTIMAVkRIRATVN K93-ub
MKK3 iso2 (human) SGTIMAVKRIRATVN K64
MKK3 iso3 (human) SGTIMAVKRIRATVN K98
MKK3 (mouse) SGTIMAVKRIRATVN K93
MKK3 (rat) SGTIMAVKRIRATVN K165
K192-ub
SVIHRDVkPSNVLIN
0 2
MKK3 (human) SVIHRDVkPSNVLIN K192-ub
MKK3 iso2 (human) SVIHRDVKPSNVLIN K163
MKK3 iso3 (human) SVIHRDVKPSNVLIN K197
MKK3 (mouse) SVIHRDVKPSNVLIN K192
MKK3 (rat) SVIHRDVKPSNVLIN K264
K192-sm
SVIHRDVkPSNVLIN
0 1
MKK3 (human) SVIHRDVkPSNVLIN K192-sm
MKK3 iso2 (human) SVIHRDVKPSNVLIN K163
MKK3 iso3 (human) SVIHRDVKPSNVLIN K197
MKK3 (mouse) SVIHRDVKPSNVLIN K192
MKK3 (rat) SVIHRDVKPSNVLIN K264
K200
PSNVLINKEGHVKMC
0 1
MKK3 (human) PSNVLINKEGHVKMC K200
MKK3 iso2 (human) PSNVLINKEGHVKMC K171
MKK3 iso3 (human) PSNVLINKEGHVKMC K205
MKK3 (mouse) PSNVLINkEGHVKMC K200-ac
MKK3 (rat) PSNVLINKEGHVKMC K272
K200-ub
PSNVLINkEGHVKMC
0 1
MKK3 (human) PSNVLINkEGHVKMC K200-ub
MKK3 iso2 (human) PSNVLINKEGHVKMC K171
MKK3 iso3 (human) PSNVLINKEGHVKMC K205
MKK3 (mouse) PSNVLINKEGHVKMC K200
MKK3 (rat) PSNVLINKEGHVKMC K272
S212-p
KMCDFGIsGyLVDsV
0 4
MKK3 (human) KMCDFGIsGyLVDsV S212-p
MKK3 iso2 (human) KMCDFGISGYLVDSV S183
MKK3 iso3 (human) KMCDFGISGYLVDSV S217
MKK3 (mouse) KMCDFGISGYLVDsV S212
MKK3 (rat) KMCDFGISGYLVDsV S284
Y214-p
CDFGIsGyLVDsVAK
0 10
MKK3 (human) CDFGIsGyLVDsVAK Y214-p
MKK3 iso2 (human) CDFGISGYLVDSVAK Y185
MKK3 iso3 (human) CDFGISGYLVDSVAK Y219
MKK3 (mouse) CDFGISGYLVDsVAK Y214
MKK3 (rat) CDFGISGYLVDsVAK Y286
S218-p
IsGyLVDsVAKtMDA
Upstream
Downstream
17 85
MKK3 (human)
S218-p
MKK3 (mouse)
S218-p
MKK3 (rat)
S290-p
Effects on Modified Protein
  • enzymatic activity, induced
Effects on Biological Processes:
  • signaling pathway regulation
  • transcription, induced
Kinase, in vitro:
  • ASK1 (human)
  • Cot (human)
  • MEKK3 (mouse)
  • MKK3 (human)
view more >
Putative in vivo kinases:
  • MLK3 (human)
Regulatory protein:
  • APOL1 (human)
Treatment
  • 2-deoxyglucose
  • IL-13
  • ischemia
  • pneumolysin
  • PP2
  • PP3
  • SB203580
  • SU6656
  • TAK1_inhibitor
  • TNF
  • vanadate
view more >
MKK3 (human) IsGyLVDsVAKtMDA S218-p
MKK3 iso2 (human) ISGYLVDSVAKTMDA S189
MKK3 iso3 (human) ISGYLVDSVAKTMDA S223
MKK3 (mouse) ISGYLVDsVAKTMDA S218-p
MKK3 (rat) ISGYLVDsVAKTMDA S290-p
T222-p
LVDsVAKtMDAGCKP
Upstream
Downstream
6 4
Effects on Modified Protein
  • activity, induced
  • enzymatic activity, induced
Effects on Biological Processes:
  • cell cycle regulation
  • transcription, induced
Kinase, in vitro:
  • MKK3 (human)
Phosphatases, in vitro:
  • PPP2CA (human)
Putative in vivo kinases:
  • MLK3 (human)
Putative upstream phosphatases:
  • PPP2CA (human)
Treatment
  • sorbitol
MKK3 (human) LVDsVAKtMDAGCKP T222-p
MKK3 iso2 (human) LVDSVAKTMDAGCKP T193
MKK3 iso3 (human) LVDSVAKTMDAGCKP T227
MKK3 (mouse) LVDsVAKTMDAGCKP T222
MKK3 (rat) LVDsVAKTMDAGCKP T294
Y230-p
MDAGCKPyMAPERIN
0 3
MKK3 (human) MDAGCKPyMAPERIN Y230-p
MKK3 iso2 (human) MDAGCKPYMAPERIN Y201
MKK3 iso3 (human) MDAGCKPYMAPERIN Y235
MKK3 (mouse) MDAGCKPYMAPERIN Y230
MKK3 (rat) MDAGCKPYMAPERIN Y302
K243-ub
INPELNQkGyNVKsD
Upstream
0 8
Treatment
  • MG132
MKK3 (human) INPELNQkGyNVKsD K243-ub
MKK3 iso2 (human) INPELNQKGYNVKSD K214
MKK3 iso3 (human) INPELNQKGYNVKSD K248
MKK3 (mouse) INPELNQkGYNVKSD K243-ub
MKK3 (rat) INPELNQKGYNVKSD K315
Y245-p
PELNQkGyNVKsDVW
0 1
MKK3 (human) PELNQkGyNVKsDVW Y245-p
MKK3 iso2 (human) PELNQKGYNVKSDVW Y216
MKK3 iso3 (human) PELNQKGYNVKSDVW Y250
MKK3 (mouse) PELNQkGYNVKSDVW Y245
MKK3 (rat) PELNQKGYNVKSDVW Y317
S249-p
QkGyNVKsDVWsLGI
0 2
MKK3 (human) QkGyNVKsDVWsLGI S249-p
MKK3 iso2 (human) QKGYNVKSDVWSLGI S220
MKK3 iso3 (human) QKGYNVKSDVWSLGI S254
MKK3 (mouse) QkGYNVKSDVWSLGI S249
MKK3 (rat) QKGYNVKSDVWSLGI S321
S253-p
NVKsDVWsLGITMIE
0 1
MKK3 (human) NVKsDVWsLGITMIE S253-p
MKK3 iso2 (human) NVKSDVWSLGITMIE S224
MKK3 iso3 (human) NVKSDVWSLGITMIE S258
MKK3 (mouse) NVKSDVWSLGITMIE S253
MKK3 (rat) NVKSDVWSLGITMIE S325
K279-ub
GTPFQQLkQVVEEPS
0 2
MKK3 (human) GTPFQQLkQVVEEPS K279-ub
MKK3 iso2 (human) GTPFQQLKQVVEEPS K250
MKK3 iso3 (human) GTPFQQLKQVVEEPS K284
MKK3 (mouse) GTPFQQLKQVVEEPS K279
MKK3 (rat) GTPFQQLKQVVEEPS K351
K332-ub
FTLHKTKkTDIAAFV
0 1
MKK3 (human) FTLHKTKkTDIAAFV K332-ub
MKK3 iso2 (human) FTLHKTKKTDIAAFV K303
MKK3 iso3 (human) FTLHKTKKTDIAAFV K337
MKK3 (mouse) FTLHKTKKTDIAAFV K332
MKK3 (rat) FTLHKTKKTDIAAFV K404
K340-ub
TDIAAFVkEILGEDS
0 2
MKK3 (human) TDIAAFVkEILGEDS K340-ub
MKK3 iso2 (human) TDIAAFVKEILGEDS K311
MKK3 iso3 (human) TDIAAFVKEILGEDS K345
MKK3 (mouse) TDIAAFVKEILGEDS K340
MKK3 (rat) TDIAAFVKEILGEDS K412