Other Species / Isoforms
  MDC1 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
T4-p
____MEDtQAIDWDV
Upstream
Downstream
2 4
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
Effects on Biological Processes:
  • cell cycle regulation
Kinase, in vitro:
  • PLK1 (human)
Putative in vivo kinases:
  • ATM (human)
  • PLK1 (human)
Treatment
  • caffeine
  • camptothecin
  • KU-55933
  • nocodazole
  • NU7026
  • VE-821
MDC1 (human) ____MEDtQAIDWDV T4-p
MDC1 iso2 (human) ____MEDTQAIDWDV T4
MDC1 (mouse) ____MESTQVIDWDA T4
MDC1 (rat) ____MENTQVIDWDA T4
MDC1 (cow) gap -
T17-p
DVEEEEEtEQssESL
0 1
MDC1 (human) DVEEEEEtEQssESL T17-p
MDC1 iso2 (human) DVEEEEETEQSSESL T17
MDC1 (mouse) DAEEEEETELSSGSL T17
MDC1 (rat) DAEEEEETEISSGSL T17
MDC1 (cow) gap -
S20-p
EEEEtEQssESLRCN
Upstream
Downstream
1 0
Effects on Modified Protein
  • intracellular localization
Effects on Biological Processes:
  • cell cycle regulation
Kinase, in vitro:
  • PLK1 (human)
MDC1 (human) EEEEtEQssESLRCN S20-p
MDC1 iso2 (human) EEEETEQSSESLRCN S20
MDC1 (mouse) EEEETELSSGSLGYS S20
MDC1 (rat) EEEETEISSGSLGYS S20
MDC1 (cow) gap -
S21-p
EEEtEQssESLRCNV
0 1
MDC1 (human) EEEtEQssESLRCNV S21-p
MDC1 iso2 (human) EEETEQSSESLRCNV S21
MDC1 (mouse) EEETELSSGSLGYSV S21
MDC1 (rat) EEETEISSGSLGYSV S21
MDC1 (cow) gap -
K45-m2
SGAHGPEkDFPLHLG
1 0
MDC1 (human) SGAHGPEkDFPLHLG K45-m2
MDC1 iso2 (human) SGAHGPEKDFPLHLG K45
MDC1 (mouse) SGTHGPERDFPLYLG R45
MDC1 (rat) SGTHGPERDFPLYLG R45
MDC1 (cow) gap -
K45-ub
SGAHGPEkDFPLHLG
0 1
MDC1 (human) SGAHGPEkDFPLHLG K45-ub
MDC1 iso2 (human) SGAHGPEKDFPLHLG K45
MDC1 (mouse) SGTHGPERDFPLYLG R45
MDC1 (rat) SGTHGPERDFPLYLG R45
MDC1 (cow) gap -
S94-p
PILRDCGsLNGtQIL
0 1
MDC1 (human) PILRDCGsLNGtQIL S94-p
MDC1 iso2 (human) PILRDCGSLNGTQIL S94
MDC1 (mouse) PILQDCGSLNGTQIV S94
MDC1 (rat) PILQDCGSLNGTQIV S94
MDC1 (cow) gap -
T98-p
DCGsLNGtQILRPPK
Upstream
Downstream
2 1
Effects on Modified Protein
  • molecular association, regulation
Effects on Biological Processes:
  • DNA repair, induced
  • cell cycle regulation
  • signaling pathway regulation
Kinase, in vitro:
  • ATM (human)
Putative in vivo kinases:
  • ATM (human)
Treatment
  • ionizing_radiation
  • KU-55933
MDC1 (human) DCGsLNGtQILRPPK T98-p
MDC1 iso2 (human) DCGSLNGTQILRPPK T98
MDC1 (mouse) DCGSLNGTQIVKPPR T98
MDC1 (rat) DCGSLNGTQIVKPPR T98
MDC1 (cow) gap -
S108-p
LRPPKVLsPGVsHRL
Upstream
0 10
Treatment
  • nocodazole
MDC1 (human) LRPPKVLsPGVsHRL S108-p
MDC1 iso2 (human) LRPPKVLSPGVSHRL S108
MDC1 (mouse) VKPPRVLPPGVSHRL P108
MDC1 (rat) VKPPRVLAPGVSHRL A108
MDC1 (cow) gap -
S112-p
KVLsPGVsHRLRDQE
Upstream
0 1
Treatment
  • nocodazole
MDC1 (human) KVLsPGVsHRLRDQE S112-p
MDC1 iso2 (human) KVLSPGVSHRLRDQE S112
MDC1 (mouse) RVLPPGVSHRLRDQE S112
MDC1 (rat) RVLAPGVSHRLRDQE S112
MDC1 (cow) gap -
T146-p
FVSRGPLtVEEtPRV
0 1
MDC1 (human) FVSRGPLtVEEtPRV T146-p
MDC1 iso2 (human) FVSRGPLTVEETPRV T146
MDC1 (mouse) LVPRSLLTIEKTPRI T146
MDC1 (rat) LVPRSLLTIEKTPRI T146
MDC1 (cow) gap -
T150-p
GPLtVEEtPRVQGEt
0 20
MDC1 (human) GPLtVEEtPRVQGEt T150-p
MDC1 iso2 (human) GPLTVEETPRVQGET T150
MDC1 (mouse) SLLTIEKTPRIRIEs T150
MDC1 (rat) SLLTIEKTPRIRGRS T150
MDC1 (cow) gap -
T157-p
tPRVQGEtQPQRLLL
0 10
MDC1 (human) tPRVQGEtQPQRLLL T157-p
MDC1 iso2 (human) TPRVQGETQPQRLLL T157
MDC1 (mouse) TPRIRIEsQNsRVLL S157-p
MDC1 (rat) TPRIRGRSQNSRVLL S157
MDC1 (cow) gap -
Q160
VQGEtQPQRLLLAED
0 4
MDC1 (human) VQGEtQPQRLLLAED Q160
MDC1 iso2 (human) VQGETQPQRLLLAED Q160
MDC1 (mouse) IRIEsQNsRVLLAAD S160-p
MDC1 (rat) IRGRSQNSRVLLAED S160
MDC1 (cow) gap -
S168-p
RLLLAEDsEEEVDFL
Upstream
0 87
Treatment
  • lapatinib
  • nocodazole
  • ZK-Thiazolidinone
MDC1 (human) RLLLAEDsEEEVDFL S168-p
MDC1 iso2 (human) RLLLAEDSEEEVDFL S168
MDC1 (mouse) RVLLAADsEEEGDFP S168-p
MDC1 (rat) RVLLAEDsEEEGDFP S168-p
MDC1 (cow) _____EDSEEEVDSL S3
S176-p
EEEVDFLsERRMVKK
0 9
MDC1 (human) EEEVDFLsERRMVKK S176-p
MDC1 iso2 (human) EEEVDFLSERRMVKK S176
MDC1 (mouse) EEEGDFPsGRCVANG S176-p
MDC1 (rat) EEEGDFPsGRSVANG S176-p
MDC1 (cow) EEEVDSLLDKCVVKG L11
S196-p
SSVIVPEsDEEGHsP
0 1
MDC1 (human) SSVIVPEsDEEGHsP S196-p
MDC1 iso2 (human) SSVIVPESDEEGHSP S196
MDC1 (mouse) SATVVPESDEEVSSP S198
MDC1 (rat) SATVVPESDEEGSSP S198
MDC1 (cow) LATVVPESDEEGPSP S31
S202-p
EsDEEGHsPVLGGLG
0 1
MDC1 (human) EsDEEGHsPVLGGLG S202-p
MDC1 iso2 (human) ESDEEGHSPVLGGLG S202
MDC1 (mouse) ESDEEVSSPAPSVPG S204
MDC1 (rat) ESDEEGSSPGPSVPG S204
MDC1 (cow) ESDEEGPSPAPDGPG S37
S218-p
PFAFNLNsDtDVEEG
Upstream
Downstream
1 7
Effects on Modified Protein
  • molecular association, regulation
Effects on Biological Processes:
  • cell cycle regulation
Putative in vivo kinases:
  • CK2A1 (human)
Treatment
  • DMAT
MDC1 (human) PFAFNLNsDtDVEEG S218-p
MDC1 iso2 (human) PFAFNLNSDTDVEEG S218
MDC1 (mouse) SSPFGLGSDTDEEQG S220
MDC1 (rat) SSPFGLGSDTDESQG S220
MDC1 (cow) PSAFNLNSDTDEEES S53
T220-p
AFNLNsDtDVEEGQQ
Upstream
Downstream
1 6
Effects on Modified Protein
  • molecular association, regulation
Effects on Biological Processes:
  • cell cycle regulation
Putative in vivo kinases:
  • CK2A1 (human)
Treatment
  • DMAT
MDC1 (human) AFNLNsDtDVEEGQQ T220-p
MDC1 iso2 (human) AFNLNSDTDVEEGQQ T220
MDC1 (mouse) PFGLGSDTDEEQGQQ T222
MDC1 (rat) PFGLGSDTDESQGQQ T222
MDC1 (cow) AFNLNSDTDEEESQE T55
T242-p
SAARRGAtVEAKQSE
0 3
MDC1 (human) SAARRGAtVEAKQSE T242-p
MDC1 iso2 (human) SAARRGATVEAKQSE T242
MDC1 (mouse) LADSSGAAGEAEQPE A244
MDC1 (rat) LADNSGAAGEPEQPE A244
MDC1 (cow) SAPRRGTAAETEQPK A77
R276-m1
DNDTKVKrGAGNGVV
0 1
MDC1 (human) DNDTKVKrGAGNGVV R276-m1
MDC1 iso2 (human) DNDTKVKRGAGNGVV R276
MDC1 (mouse) LKDTKVKKEAGRAGV K275
MDC1 (rat) FKDTKMKEEAGSAGV E275
MDC1 (cow) NRDTEIERDVKNGVV R110
S292-p
AGVILERsQPPGEDs
0 6
MDC1 (human) AGVILERsQPPGEDs S292-p
MDC1 iso2 (human) AGVILERSQPPGEDS S292
MDC1 (mouse) DGSVLERsPTLGEDs S291-p
MDC1 (rat) VGSVVEGSPTLGEDs S291
MDC1 (cow) TGVILERSQPSGEDS S126
S299-p
sQPPGEDsDtDVDDD
Upstream
Downstream
1 41
Effects on Modified Protein
  • molecular association, regulation
Effects on Biological Processes:
  • cell cycle regulation
Putative in vivo kinases:
  • CK2A1 (human)
Treatment
  • DMAT
  • ischemia
  • SII_angiotensin_2
MDC1 (human) sQPPGEDsDtDVDDD S299-p
MDC1 iso2 (human) SQPPGEDSDTDVDDD S299
MDC1 (mouse) sPTLGEDsDtEVDED S298-p
MDC1 (rat) SPTLGEDsDTEADEE S298-p
MDC1 (cow) SQPSGEDSDTDVSDE S133
T301-p
PPGEDsDtDVDDDsR
Upstream
Downstream
1 43
Effects on Modified Protein
  • molecular association, regulation
Effects on Biological Processes:
  • cell cycle regulation
Putative in vivo kinases:
  • CK2A1 (human)
Treatment
  • DMAT
  • SII_angiotensin_2
MDC1 (human) PPGEDsDtDVDDDsR T301-p
MDC1 iso2 (human) PPGEDSDTDVDDDSR T301
MDC1 (mouse) TLGEDsDtEVDEDHK T300-p
MDC1 (rat) TLGEDsDTEADEERQ T300
MDC1 (cow) PSGEDSDTDVSDESG T135
S307-p
DtDVDDDsRPPGRPA
0 1
MDC1 (human) DtDVDDDsRPPGRPA S307-p
MDC1 iso2 (human) DTDVDDDSRPPGRPA S307
MDC1 (mouse) DtEVDEDHKPGFADs H306
MDC1 (rat) DTEADEERQPSGSGD R306
MDC1 (cow) DTDVSDESGPPRRLA S141
S329-p
QPFGFIDsDtDAEEE
Upstream
Downstream
1 51
Effects on Modified Protein
  • molecular association, regulation
Effects on Biological Processes:
  • cell cycle regulation
Putative in vivo kinases:
  • CK2A1 (human)
Treatment
  • DMAT
  • nocodazole
MDC1 (human) QPFGFIDsDtDAEEE S329-p
MDC1 iso2 (human) QPFGFIDSDTDAEEE S329
MDC1 (mouse) HKPGFADsEtDVEEE S313-p
MDC1 (rat) QPSGSGDSDTDVEEE S314
MDC1 (cow) WSCNFIDSDTDGEDK S163
T331-p
FGFIDsDtDAEEERI
Upstream
Downstream
1 48
Effects on Modified Protein
  • molecular association, regulation
Effects on Biological Processes:
  • cell cycle regulation
Putative in vivo kinases:
  • CK2A1 (human)
Treatment
  • DMAT
  • nocodazole
MDC1 (human) FGFIDsDtDAEEERI T331-p
MDC1 iso2 (human) FGFIDSDTDAEEERI T331
MDC1 (mouse) PGFADsEtDVEEERI T315-p
MDC1 (rat) SGSGDSDTDVEEERV T316
MDC1 (cow) CNFIDSDTDGEDKGI T165
T341-p
EEERIPAtPVVIPMK
Upstream
1 24
Kinase, in vitro:
  • CDK2 (human)
MDC1 (human) EEERIPAtPVVIPMK T341-p
MDC1 iso2 (human) EEERIPATPVVIPMK T341
MDC1 (mouse) EEERIPVtPPVAPVK T325-p
MDC1 (rat) gap -
MDC1 (cow) EDKGIPAAPAVVPMK A175
S372-p
GLAHLQEsQAGsDtD
Upstream
0 29
Treatment
  • BI_4834
MDC1 (human) GLAHLQEsQAGsDtD S372-p
MDC1 iso2 (human) GLAHLQESQAGSDTD S372
MDC1 (mouse) GVAHLQDCLAGSGTD C356
MDC1 (rat) GVAHLQDsPTGsDtD S350-p
MDC1 (cow) GVACRQESPADGDTD S206
S376-p
LQEsQAGsDtDVEEG
Upstream
Downstream
1 51
Effects on Modified Protein
  • molecular association, regulation
Effects on Biological Processes:
  • cell cycle regulation
Putative in vivo kinases:
  • CK2A1 (human)
Treatment
  • DMAT
  • metastatic potential
MDC1 (human) LQEsQAGsDtDVEEG S376-p
MDC1 iso2 (human) LQESQAGSDTDVEEG S376
MDC1 (mouse) LQDCLAGSGTDVEDK S360
MDC1 (rat) LQDsPTGsDtDVEED S354-p
MDC1 (cow) RQESPADGDTDIEEG G210
T378-p
EsQAGsDtDVEEGKA
Upstream
Downstream
1 46
Effects on Modified Protein
  • molecular association, regulation
Effects on Biological Processes:
  • cell cycle regulation
Putative in vivo kinases:
  • CK2A1 (human)
Treatment
  • DMAT
MDC1 (human) EsQAGsDtDVEEGKA T378-p
MDC1 iso2 (human) ESQAGSDTDVEEGKA T378
MDC1 (mouse) DCLAGSGTDVEDKTA T362
MDC1 (rat) DsPTGsDtDVEEDKT T356-p
MDC1 (cow) ESPADGDTDIEEGEA T212
S394-p
QAVPLEKsQAsMVIN
0 1
MDC1 (human) QAVPLEKsQAsMVIN S394-p
MDC1 iso2 (human) QAVPLEKSQASMVIN S394
MDC1 (mouse) LDVPLERNHTPMVIN N377
MDC1 (rat) LAAPPERSHTAMVIN S372
MDC1 (cow) GEAPLDRSQASMVID S224
S397-p
PLEKsQAsMVINsDt
0 3
MDC1 (human) PLEKsQAsMVINsDt S397-p
MDC1 iso2 (human) PLEKSQASMVINSDT S397
MDC1 (mouse) PLERNHTPMVINsDt P380
MDC1 (rat) PPERSHTAMVINsDt A375
MDC1 (cow) PLDRSQASMVIDSNT S227
S402-p
QAsMVINsDtDDEEE
Upstream
Downstream
1 34
Effects on Modified Protein
  • molecular association, regulation
Effects on Biological Processes:
  • cell cycle regulation
Putative in vivo kinases:
  • CK2A1 (human)
Treatment
  • DMAT
  • EGF
  • SB202190
MDC1 (human) QAsMVINsDtDDEEE S402-p
MDC1 iso2 (human) QASMVINSDTDDEEE S402
MDC1 (mouse) HTPMVINsDtDEEEE S385-p
MDC1 (rat) HTAMVINsDtDEEER S380-p
MDC1 (cow) QASMVIDSNTDDEEE S232
T404-p
sMVINsDtDDEEEVs
Upstream
Downstream
1 29
Effects on Modified Protein
  • molecular association, regulation
Effects on Biological Processes:
  • cell cycle regulation
Putative in vivo kinases:
  • CK2A1 (human)
Treatment
  • DMAT
  • EGF
  • SB202190
MDC1 (human) sMVINsDtDDEEEVs T404-p
MDC1 iso2 (human) SMVINSDTDDEEEVS T404
MDC1 (mouse) NsDtDEEEEEEEEVS E391
MDC1 (rat) sDtDEEERGEEEEVS R387
MDC1 (cow) gap -
S411-p
tDDEEEVsAALTLAH
0 4
MDC1 (human) tDDEEEVsAALTLAH S411-p
MDC1 iso2 (human) TDDEEEVSAALTLAH S411
MDC1 (mouse) EEEEEEVSAALTLAH S398
MDC1 (rat) RGEEEEVSAALTLAR S394
MDC1 (cow) TDDEEEVSAALTLAR S241
S422-p
TLAHLKEsQPAIWNr
0 2
MDC1 (human) TLAHLKEsQPAIWNr S422-p
MDC1 iso2 (human) TLAHLKESQPAIWNR S422
MDC1 (mouse) TLAHLKERGIGLWSR R409
MDC1 (rat) TLARLKERGIALWsG R405
MDC1 (cow) TLARLRESQAGKWNR S252
N428
EsQPAIWNrDAEEDM
0 1
MDC1 (human) EsQPAIWNrDAEEDM N428
MDC1 iso2 (human) ESQPAIWNRDAEEDM N428
MDC1 (mouse) ERGIGLWSRDPGAEE S415
MDC1 (rat) ERGIALWsGEPGTEE S411-p
MDC1 (cow) ESQAGKWNRDPDAEE N258
R429-m1
sQPAIWNrDAEEDMP
0 1
MDC1 (human) sQPAIWNrDAEEDMP R429-m1
MDC1 iso2 (human) SQPAIWNRDAEEDMP R429
MDC1 (mouse) RGIGLWSRDPGAEEV R416
MDC1 (rat) RGIALWsGEPGTEEV G412
MDC1 (cow) SQAGKWNRDPDAEED R259
P436
rDAEEDMPQRVVLLQ
0 1
MDC1 (human) rDAEEDMPQRVVLLQ P436
MDC1 iso2 (human) RDAEEDMPQRVVLLQ P436
MDC1 (mouse) PGAEEVKSQPQVLVE S425
MDC1 (rat) PGTEEVKsQPQVLVE S421-p
MDC1 (cow) PDAEEDRAQPVALLE A268
S445-p
RVVLLQRsQtttERD
0 40
MDC1 (human) RVVLLQRsQtttERD S445-p
MDC1 iso2 (human) RVVLLQRSQTTTERD S445
MDC1 (mouse) PQVLVEQsQSAsGRD S434-p
MDC1 (rat) PQVLVERSQSASGRD S430
MDC1 (cow) PVALLERSQASARGD S277
T447-p
VLLQRsQtttERDsD
Upstream
0 84
Treatment
  • imatinib
MDC1 (human) VLLQRsQtttERDsD T447-p
MDC1 iso2 (human) VLLQRSQTTTERDSD T447
MDC1 (mouse) VLVEQsQSAsGRDsD S436
MDC1 (rat) VLVERSQSASGRDsD S432
MDC1 (cow) ALLERSQASARGDSD A279
T448-p
LLQRsQtttERDsDt
0 45
MDC1 (human) LLQRsQtttERDsDt T448-p
MDC1 iso2 (human) LLQRSQTTTERDSDT T448
MDC1 (mouse) LVEQsQSAsGRDsDt A437
MDC1 (rat) LVERSQSASGRDsDt A433
MDC1 (cow) LLERSQASARGDSDT S280
T449-p
LQRsQtttERDsDtD
Upstream
0 68
Treatment
  • imatinib
MDC1 (human) LQRsQtttERDsDtD T449-p
MDC1 iso2 (human) LQRSQTTTERDSDTD T449
MDC1 (mouse) VEQsQSAsGRDsDtD S438-p
MDC1 (rat) VERSQSASGRDsDtD S434
MDC1 (cow) LERSQASARGDSDTD A281
S453-p
QtttERDsDtDVEEE
Upstream
Downstream
1 127
Effects on Modified Protein
  • molecular association, regulation
Effects on Biological Processes:
  • cell cycle regulation
Putative in vivo kinases:
  • CK2A1 (human)
Treatment
  • DMAT
  • imatinib
MDC1 (human) QtttERDsDtDVEEE S453-p
MDC1 iso2 (human) QTTTERDSDTDVEEE S453
MDC1 (mouse) QSAsGRDsDtDVEEE S442-p
MDC1 (rat) QSASGRDsDtDVEEG S438-p
MDC1 (cow) QASARGDSDTDVEEE S285
T455-p
ttERDsDtDVEEEEL
Upstream
Downstream
1 129
Effects on Modified Protein
  • molecular association, regulation
Effects on Biological Processes:
  • cell cycle regulation
Putative in vivo kinases:
  • CK2A1 (human)
Treatment
  • DMAT
  • nocodazole
MDC1 (human) ttERDsDtDVEEEEL T455-p
MDC1 iso2 (human) TTERDSDTDVEEEEL T455
MDC1 (mouse) AsGRDsDtDVEEESS T444-p
MDC1 (rat) ASGRDsDtDVEEGSS T440-p
MDC1 (cow) SARGDSDTDVEEEGL T287
K472-ub
ENREAVLkDHTkIRA
0 1
MDC1 (human) ENREAVLkDHTkIRA K472-ub
MDC1 iso2 (human) ENREAVLKDHTKIRA K472
MDC1 (mouse) gap -
MDC1 (rat) gap -
MDC1 (cow) GRRGMVPKGHMDREY K304
K540-ub
SAIIHIKkHQVsVEG
0 1
MDC1 (human) SAIIHIKkHQVsVEG K540-ub
MDC1 iso2 (human) SAIIHIKKHQVSVEG K540
MDC1 (mouse) PSVILGEKHQVPLEG K529
MDC1 (rat) PSVTLGEKHQVPLEG K525
MDC1 (cow) PAVALPEKHQVQGIV K361
S641-p
VEQDLPIsRENLtDL
0 1
MDC1 (human) VEQDLPIsRENLtDL S641-p
MDC1 iso2 (human) VEQDLPISRENLTDL S641
MDC1 (mouse) gap -
MDC1 (rat) gap -
MDC1 (cow) EQDLLPVSRENLANP S461
S760-p
QPFCLREsEDsEtQP
0 3
MDC1 (human) QPFCLREsEDsEtQP S760-p
MDC1 iso2 (human) gap -
MDC1 (mouse) PFCLREQsETSELHE S721-p
MDC1 (rat) gap -
MDC1 (cow) QPFCPREYEASETQT Y581
G825
KETAERVGPERGPLE
0 6
MDC1 (human) KETAERVGPERGPLE G825
MDC1 iso2 (human) gap -
MDC1 (mouse) KEMADRMtPEREPLE T782-p
MDC1 (rat) gap -
MDC1 (cow) RETAERVIPEGGPPQ I646
S882-p
DKNGEsAsPERDRES
0 7
MDC1 (human) DKNGEsAsPERDRES S882-p
MDC1 iso2 (human) gap -
MDC1 (mouse) gap -
MDC1 (rat) gap -
MDC1 (cow) DKTVKSASTGRGMEI S704
S964-p
DQKGQAssPtPEPGV
0 4
MDC1 (human) DQKGQAssPtPEPGV S964-p
MDC1 iso2 (human) gap -
MDC1 (mouse) DQKGQIASLTLKPGV S894
MDC1 (rat) gap -
MDC1 (cow) DQKGQASGPPSEPGA G786
S1212-p
TALELQPsTsTDRPV
0 1
MDC1 (human) TALELQPsTsTDRPV S1212-p
MDC1 iso2 (human) TALELQPSTSTDRPV S948
MDC1 (mouse) gap -
MDC1 (rat) gap -
MDC1 (cow) gap -
T1239-p
KNRSSVKtPEPVVPT
Upstream
0 5
Treatment
  • SII_angiotensin_2
MDC1 (human) KNRSSVKtPEPVVPT T1239-p
MDC1 iso2 (human) KNRSSVKTPEPVVPT T975
MDC1 (mouse) gap -
MDC1 (rat) gap -
MDC1 (cow) gap -
T1343-p
TStDQPVtPkPtsRT
0 14
MDC1 (human) TStDQPVtPkPtsRT T1343-p
MDC1 iso2 (human) TSTDQPVTPKPTSRT T1079
MDC1 (mouse) gap -
MDC1 (rat) gap -
MDC1 (cow) gap -
T1384-p
TSTEQPVtPEPTSRA
0 9
MDC1 (human) TSTEQPVtPEPTSRA T1384-p
MDC1 iso2 (human) TSTEQPVTPEPTSRA T1120
MDC1 (mouse) gap -
MDC1 (rat) gap -
MDC1 (cow) gap -
S1399-p
TRGRKNRssGktPEt
Upstream
0 10
Treatment
  • EGF
  • nocodazole
MDC1 (human) TRGRKNRssGktPEt S1399-p
MDC1 iso2 (human) TRGRKNRSSGKTPET S1135
MDC1 (mouse) gap -
MDC1 (rat) gap -
MDC1 (cow) gap -
S1605-p
RCRtNRssVKtPEPV
Upstream
0 2
Treatment
  • MLN8054
MDC1 (human) RCRtNRssVKtPEPV S1605-p
MDC1 iso2 (human) RCRTNRSSVKTPEPV S1341
MDC1 (mouse) gap -
MDC1 (rat) gap -
MDC1 (cow) QCRRHRSSVKTPEPV S1286
S1775-p
TAIPEPAsPQLLEtP
Upstream
0 26
Treatment
  • angiotensin_2
  • anti-CD3
  • ischemia
  • nocodazole
MDC1 (human) TAIPEPAsPQLLEtP S1775-p
MDC1 iso2 (human) TAIPEPASPQLLETP S1511
MDC1 (mouse) gap -
MDC1 (rat) gap -
MDC1 (cow) STISEPAFAQLPEAP F1455
K1812-ac
PKASQsRkRsLAtMD
0 1
MDC1 (human) PKASQsRkRsLAtMD K1812-ac
MDC1 iso2 (human) PKASQSRKRSLATMD K1548
MDC1 (mouse) gap -
MDC1 (rat) gap -
MDC1 (cow) PRASQNRKRPSATAH K1492
-
gap
0 4
MDC1 (human) gap -
MDC1 iso2 (human) gap -
MDC1 (mouse) KREIIPDsPMDVDEA S461-p
MDC1 (rat) KREIVPDSPMDVDET S457
MDC1 (cow) gap -
K476-ub
AVLkDHTkIRALVRA
0 1
MDC1 (human) AVLkDHTkIRALVRA K476-ub
MDC1 iso2 (human) AVLKDHTKIRALVRA K476
MDC1 (mouse) gap -
MDC1 (rat) gap -
MDC1 (cow) gap -
R482
TkIRALVRAHsEKDQ
0 1
MDC1 (human) TkIRALVRAHsEKDQ R482
MDC1 iso2 (human) TKIRALVRAHSEKDQ R482
MDC1 (mouse) MDVDEALtVTQPESQ T470-p
MDC1 (rat) MDVDETLTVTQPESQ T466
MDC1 (cow) VPKGHMDREYSKKSQ R309
S485-p
RALVRAHsEKDQPPF
Upstream
0 15
Treatment
  • SII_angiotensin_2
MDC1 (human) RALVRAHsEKDQPPF S485-p
MDC1 iso2 (human) RALVRAHSEKDQPPF S485
MDC1 (mouse) DEALtVTQPESQPPR Q473
MDC1 (rat) DETLTVTQPESQPPC Q469
MDC1 (cow) GHMDREYSKKSQHPP S312
S495-p
DQPPFGDsDDsVEAD
Upstream
0 24
Regulatory protein:
  • PRP4 (human)
Treatment
  • dasatinib
MDC1 (human) DQPPFGDsDDsVEAD S495-p
MDC1 iso2 (human) DQPPFGDSDDSVEAD S495
MDC1 (mouse) SQPPRRPNDADEYMD N483
MDC1 (rat) SQPPCRPNDVDEDVD N479
MDC1 (cow) SQHPPRDSDTEGKKD S322
S498-p
PFGDsDDsVEADKss
Upstream
0 24
Regulatory protein:
  • PRP4 (human)
Treatment
  • dasatinib
MDC1 (human) PFGDsDDsVEADKss S498-p
MDC1 iso2 (human) PFGDSDDSVEADKSS S498
MDC1 (mouse) PRRPNDADEYMDMss D486
MDC1 (rat) PCRPNDVDEDVDMSS D482
MDC1 (cow) PPRDSDTEGKKDESS E325
S504-p
DsVEADKssPGIHLE
0 6
MDC1 (human) DsVEADKssPGIHLE S504-p
MDC1 iso2 (human) DSVEADKSSPGIHLE S504
MDC1 (mouse) ADEYMDMssPGsHLV S492-p
MDC1 (rat) VDEDVDMSSPGSHLE S488
MDC1 (cow) TEGKKDESSPGVHLE S331
S505-p
sVEADKssPGIHLER
0 10
MDC1 (human) sVEADKssPGIHLER S505-p
MDC1 iso2 (human) SVEADKSSPGIHLER S505
MDC1 (mouse) DEYMDMssPGsHLVV S493-p
MDC1 (rat) DEDVDMSSPGSHLEG S489
MDC1 (cow) EGKKDESSPGVHLER S332
I508
ADKssPGIHLERsQA
0 1
MDC1 (human) ADKssPGIHLERsQA I508
MDC1 iso2 (human) ADKSSPGIHLERSQA I508
MDC1 (mouse) MDMssPGsHLVVNQA S496-p
MDC1 (rat) VDMSSPGSHLEGKKA S492
MDC1 (cow) KDESSPGVHLERSQA V335
S513-p
PGIHLERsQAsTtVD
Upstream
0 32
Putative in vivo kinases:
  • ATR (human)
Treatment
  • nocodazole
  • UV
MDC1 (human) PGIHLERsQAsTtVD S513-p
MDC1 iso2 (human) PGIHLERSQASTTVD S513
MDC1 (mouse) PGsHLVVNQASFAVV N501
MDC1 (rat) PGSHLEGKKASSALV K497
MDC1 (cow) PGVHLERSQASAQVE S340
S516-p
HLERsQAsTtVDINt
0 2
MDC1 (human) HLERsQAsTtVDINt S516-p
MDC1 iso2 (human) HLERSQASTTVDINT S516
MDC1 (mouse) HLVVNQASFAVVGKT S504
MDC1 (rat) HLEGKKASSALVDKN S500
MDC1 (cow) HLERSQASAQVEDEV S343
S955-p
RGEPEGGsQDQKGQA
0 10
MDC1 (human) RGEPEGGsQDQKGQA S955-p
MDC1 iso2 (human) gap -
MDC1 (mouse) RGVTEEGsHDQKGQI S885-p
MDC1 (rat) gap -
MDC1 (cow) MRETEAGGQDQKGQA G777
T518-p
ERsQAsTtVDINtQV
0 1
MDC1 (human) ERsQAsTtVDINtQV T518-p
MDC1 iso2 (human) ERSQASTTVDINTQV T518
MDC1 (mouse) VVNQASFAVVGKTRA A506
MDC1 (rat) EGKKASSALVDKNRA A502
MDC1 (cow) gap -
T523-p
sTtVDINtQVEKEVP
Upstream
0 4
Kinase, in vitro:
  • Chk1 (human)
MDC1 (human) sTtVDINtQVEKEVP T523-p
MDC1 iso2 (human) STTVDINTQVEKEVP T523
MDC1 (mouse) SFAVVGKTRAQVEEE T511
MDC1 (rat) SSALVDKNRAQVEEE N507
MDC1 (cow) LERSQASAQVEDEVP A344
S544-p
HIKkHQVsVEGtNQT
0 5
MDC1 (human) HIKkHQVsVEGtNQT S544-p
MDC1 iso2 (human) HIKKHQVSVEGTNQT S544
MDC1 (mouse) LGEKHQVPLEGAQPP P533
MDC1 (rat) LGEKHQVPLEGAQPP P529
MDC1 (cow) LPEKHQVQGIVWTHH Q365
T548-p
HQVsVEGtNQTDVKA
0 1
MDC1 (human) HQVsVEGtNQTDVKA T548-p
MDC1 iso2 (human) HQVSVEGTNQTDVKA T548
MDC1 (mouse) HQVPLEGAQPPEEAW A537
MDC1 (rat) HQVPLEGAQPPEEAR A533
MDC1 (cow) QVQGIVWTHHTDAEA T370
T579-p
PLHGDCEtDAEEGTS
0 3
MDC1 (human) PLHGDCEtDAEEGTS T579-p
MDC1 iso2 (human) PLHGDCETDAEEGTS T579
MDC1 (mouse) PPEEAWETAVQEGSS T546
MDC1 (rat) PPEEARETAVQEGSs T542
MDC1 (cow) PLAGDCELDAENTSS L402
S586
tDAEEGTSLTASVVA
0 1
MDC1 (human) tDAEEGTSLTASVVA S586
MDC1 iso2 (human) TDAEEGTSLTASVVA S586
MDC1 (mouse) TAVQEGSSsPEAAAS S553
MDC1 (rat) TAVQEGSssPVADIR S549-p
MDC1 (cow) gap -
T588
AEEGTSLTASVVADV
0 1
MDC1 (human) AEEGTSLTASVVADV T588
MDC1 iso2 (human) AEEGTSLTASVVADV T588
MDC1 (mouse) AVQEGSSsPEAAASV S554-p
MDC1 (rat) gap -