Other Species / Isoforms
  LKB1 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
S31-p
TFIHRIDstEVIyQP
1 319
LKB1 (human) TFIHRIDstEVIyQP S31-p
LKB1 iso2 (human) TFIHRIDSTEVIYQP S31
LKB1 (mouse) TFIHRIDstEVIyQP S31-p
LKB1 (rat) TFIHRIDsTEVIYQP S31-p
LKB1 (pig) gap -
T32-p
FIHRIDstEVIyQPR
0 37
LKB1 (human) FIHRIDstEVIyQPR T32-p
LKB1 iso2 (human) FIHRIDSTEVIYQPR T32
LKB1 (mouse) FIHRIDstEVIyQPR T32-p
LKB1 (rat) FIHRIDsTEVIYQPR T32
LKB1 (pig) gap -
Y36-p
IDstEVIyQPRRKRA
1 16
LKB1 (human) IDstEVIyQPRRKRA Y36-p
LKB1 iso2 (human) IDSTEVIYQPRRKRA Y36
LKB1 (mouse) IDstEVIyQPRRKRA Y36-p
LKB1 (rat) IDsTEVIYQPRRKRA Y36
LKB1 (pig) gap -
K44-ac
QPRRKRAkLIGkYLM
0 1
LKB1 (human) QPRRKRAkLIGkYLM K44-ac
LKB1 iso2 (human) QPRRKRAKLIGKYLM K44
LKB1 (mouse) QPRRKRAKLIGKYLM K44
LKB1 (rat) QPRRKRAKLIGKYLM K44
LKB1 (pig) gap -
K48-ac
KRAkLIGkYLMGDLL
Upstream
Downstream
2 1
Effects on Modified Protein
  • enzymatic activity, inhibited
  • intracellular localization
  • molecular association, regulation
  • phosphorylation
Treatment
  • siRNA
LKB1 (human) KRAkLIGkYLMGDLL K48-ac
LKB1 iso2 (human) KRAKLIGKYLMGDLL K48
LKB1 (mouse) KRAKLIGKYLMGDLL K48
LKB1 (rat) KRAKLIGKYLMGDLL K48
LKB1 (pig) gap -
Y60
DLLGEGSYGKVkEVL
1 0
LKB1 (human) DLLGEGSYGKVkEVL Y60
LKB1 iso2 (human) DLLGEGSYGKVKEVL Y60
LKB1 (mouse) DLLGEGSyGKVKEVL Y60-p
LKB1 (rat) DLLGEGSYGKVKEVL Y60
LKB1 (pig) gap -
K64-ac
EGSYGKVkEVLDSET
Downstream
1 0
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
  • protein degradation
  • ubiquitination
Effects on Biological Processes:
  • apoptosis, induced
  • cell cycle regulation
  • cell growth, altered
  • transcription, induced
LKB1 (human) EGSYGKVkEVLDSET K64-ac
LKB1 iso2 (human) EGSYGKVKEVLDSET K64
LKB1 (mouse) EGSyGKVKEVLDSET K64
LKB1 (rat) EGSYGKVKEVLDSET K64
LKB1 (pig) gap -
K96-ac
PNGEANVkkEIQLLR
1 1
LKB1 (human) PNGEANVkkEIQLLR K96-ac
LKB1 iso2 (human) PNGEANVKKEIQLLR K96
LKB1 (mouse) PNGEANVKKEIQLLR K96
LKB1 (rat) PNGEANVKKEIQLLR K96
LKB1 (pig) gap -
K97-ac
NGEANVkkEIQLLRR
Downstream
1 1
Effects on Modified Protein
  • enzymatic activity, inhibited
LKB1 (human) NGEANVkkEIQLLRR K97-ac
LKB1 iso2 (human) NGEANVKKEIQLLRR K97
LKB1 (mouse) NGEANVKKEIQLLRR K97
LKB1 (rat) NGEANVKKEIQLLRR K97
LKB1 (pig) gap -
Y156
PVCQAHGYFCQLIDG
1 0
LKB1 (human) PVCQAHGYFCQLIDG Y156
LKB1 iso2 (human) PVCQAHGYFCQLIDG Y156
LKB1 (mouse) PVCQAHGyFRQLIDG Y156-p
LKB1 (rat) PVCQAHGYFRQLIDG Y156
LKB1 (pig) PVCQAHGYFCQLVDG Y62
Y166
QLIDGLEYLHSQGIV
1 0
LKB1 (human) QLIDGLEYLHSQGIV Y166
LKB1 iso2 (human) QLIDGLEYLHSQGIV Y166
LKB1 (mouse) QLIDGLEyLHSQGIV Y166-p
LKB1 (rat) QLIDGLEYLHSQGIV Y166
LKB1 (pig) QLVDGLEYLHSQGIV Y72
K178-sm
GIVHKDIkPGNLLLt
Upstream
2 0
Treatment
  • 2-deoxyglucose
  • low_glucose
  • phenformin
LKB1 (human) GIVHKDIkPGNLLLt K178-sm
LKB1 iso2 (human) GIVHKDIKPGNLLLT K178
LKB1 (mouse) GIVHKDIKPGNLLLT K178
LKB1 (rat) GIVHKDIKPGNLLLT K178
LKB1 (pig) GIVHKDIKPGNLLLT K84
T185-p
kPGNLLLtTGGtLKI
Upstream
Downstream
1 0
Effects on Modified Protein
  • enzymatic activity, induced
Kinase, in vitro:
  • LKB1 (human)
LKB1 (human) kPGNLLLtTGGtLKI T185-p
LKB1 iso2 (human) KPGNLLLTTGGTLKI T185
LKB1 (mouse) KPGNLLLTTNGTLKI T185
LKB1 (rat) KPGNLLLTTNGTLKI T185
LKB1 (pig) KPGNLLLTTGGTLKI T91
T189-p
LLLtTGGtLKISDLG
Upstream
Downstream
2 0
LKB1 (human)
T189-p
Effects on Biological Processes:
  • apoptosis, inhibited
Kinase, in vitro:
  • LKB1 (human)
Treatment
  • calyculin_A
LKB1 (human) LLLtTGGtLKISDLG T189-p
LKB1 iso2 (human) LLLTTGGTLKISDLG T189
LKB1 (mouse) LLLTTNGTLKISDLG T189
LKB1 (rat) LLLTTNGTLKISDLG T189
LKB1 (pig) LLLTTGGTLKISDLG T95
S240-p
GFKVDIWsAGVTLYN
0 1
LKB1 (human) GFKVDIWsAGVTLYN S240-p
LKB1 iso2 (human) GFKVDIWSAGVTLYN S240
LKB1 (mouse) GFKVDIWSAGVTLYN S240
LKB1 (rat) GFKVDIWSAGVTLYN S240
LKB1 (pig) GFKVDIWSAGVTLYN S146
Y261
PFEGDNIYKLFENIG
3 0
LKB1 (human) PFEGDNIYKLFENIG Y261
LKB1 iso2 (human) PFEGDNIYKLFENIG Y261
LKB1 (mouse) PFEGDNIyKLFENIG Y261-p
LKB1 (rat) PFEGDNIYKLFENIG Y261
LKB1 (pig) PFEGDNIYKLFENIG Y167
K296-ac
MLEYEPAkRFSIRQI
1 0
LKB1 (human) MLEYEPAkRFSIRQI K296-ac
LKB1 iso2 (human) MLEYEPAKRFSIRQI K296
LKB1 (mouse) MLEYEPAKRFSIRQI K296
LKB1 (rat) MLEYEPAKRFSIRQI K296
LKB1 (pig) MLEYEPAKRFSIQQI K202
S307-p
IRQIRQHsWFRkKHP
Upstream
Downstream
2 0
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
Effects on Biological Processes:
  • apoptosis, altered
  • cell growth, altered
Kinase, in vitro:
  • PKCZ (human)
Putative in vivo kinases:
  • PKCZ (human)
Treatment
  • 2-deoxyglucose
  • acadesine
  • leptin
  • metformin
  • ONOO(-)
  • PKC-zeta_inhibitor
  • siRNA
  • statin
LKB1 (human) IRQIRQHsWFRkKHP S307-p
LKB1 iso2 (human) IRQIRQHSWFRKKHP S307
LKB1 (mouse) IRQIRQHSWFRKKHP S307
LKB1 (rat) IRQIRQHSWFRKKHP S307
LKB1 (pig) IQQIRQHSWFRKKHP S213
K311-ac
RQHsWFRkKHPPAEA
1 0
LKB1 (human) RQHsWFRkKHPPAEA K311-ac
LKB1 iso2 (human) RQHSWFRKKHPPAEA K311
LKB1 (mouse) RQHSWFRKKHPLAEA K311
LKB1 (rat) RQHSWFRKKHPLAEA K311
LKB1 (pig) RQHSWFRKKHPPAEE K217
S325
APVPIPPSPDTKDRW
2 0
LKB1 (human) APVPIPPSPDTKDRW S325
LKB1 iso2 (human) APVPIPPSPDTKDRW S325
LKB1 (mouse) ALVPIPPsPDTKDRW S325-p
LKB1 (rat) ALVPIPPSPDTKDRW S325
LKB1 (pig) EPVPIPPSTDCKDRW S231
S334-p
DTKDRWRsMtVVPYL
Upstream
Downstream
2 0
LKB1 (human)
S334-p
Effects on Biological Processes:
  • carcinogenesis, induced
  • cell growth, inhibited
Kinase, in vitro:
  • Pim1 (human)
Putative in vivo kinases:
  • Pim1 (human)
Treatment
  • AZD1208
  • DHPCC-9
LKB1 (human) DTKDRWRsMtVVPYL S334-p
LKB1 iso2 (human) DTKDRWRSMTVVPYL S334
LKB1 (mouse) DTKDRWRSMtVVPYL S334
LKB1 (rat) DTKDRWRSMTVVPYL S334
LKB1 (pig) DCKDRWRGMTVVPYL G240
T336-p
KDRWRsMtVVPYLED
Upstream
Downstream
2 0
Effects on Modified Protein
  • enzymatic activity, induced
Kinase, in vitro:
  • LKB1 (human)
LKB1 (human) KDRWRsMtVVPYLED T336-p
LKB1 iso2 (human) KDRWRSMTVVPYLED T336
LKB1 (mouse) KDRWRSMtVVPYLED T336-p
LKB1 (rat) KDRWRSMTVVPYLED T336
LKB1 (pig) KDRWRGMTVVPYLED T242
Y362
DIEDDIIYtQDFTVP
3 0
LKB1 (human) DIEDDIIYtQDFTVP Y362
LKB1 iso2 (human) DIEDDIIYTQDFTVP Y362
LKB1 (mouse) DIEDGIIytQDFTVP Y365-p
LKB1 (rat) DIEDGIIYTQDFTVP Y365
LKB1 (pig) DIEDDIIYTQDFTVP Y270
T363-p
IEDDIIYtQDFTVPG
Upstream
Downstream
6 0
Effects on Modified Protein
  • enzymatic activity, induced
Kinase, in vitro:
  • LKB1 (human)
LKB1 (human) IEDDIIYtQDFTVPG T363-p
LKB1 iso2 (human) IEDDIIYTQDFTVPG T363
LKB1 (mouse) IEDGIIytQDFTVPG T366-p
LKB1 (rat) IEDGIIYTQDFTVPG T366
LKB1 (pig) IEDDIIYTQDFTVPG T271
N393
LPKAVCMNGTEAAQL
0 1
LKB1 (human) LPKAVCMNGTEAAQL N393
LKB1 iso2 (human) gap -
LKB1 (mouse) LPKAVCVnGTEPQLS N396-ng
LKB1 (rat) LPKAVCVNGTEPQLS N396
LKB1 (pig) LPKAVCVNGTESVQL N301
S401-p
GTEAAQLstKsRAEG
0 2
LKB1 (human) GTEAAQLstKsRAEG S401-p
LKB1 iso2 (human) KSEGSDLSGEEAsRP S394
LKB1 (mouse) nGTEPQLSSKVKPEG S403
LKB1 (rat) NGTEPQLSSKVKPEG S403
LKB1 (pig) GTESVQLSAKSRAER S309
T402-p
TEAAQLstKsRAEGR
Upstream
Downstream
1 0
Effects on Modified Protein
  • enzymatic activity, induced
Kinase, in vitro:
  • LKB1 (human)
LKB1 (human) TEAAQLstKsRAEGR T402-p
LKB1 iso2 (human) SEGSDLSGEEAsRPA G395
LKB1 (mouse) GTEPQLSSKVKPEGR S404
LKB1 (rat) GTEPQLSSKVKPEGR S404
LKB1 (pig) TESVQLSAKSRAERR A310
S404-p
AAQLstKsRAEGRAP
0 2
LKB1 (human) AAQLstKsRAEGRAP S404-p
LKB1 iso2 (human) gap -
LKB1 (mouse) EPQLSSKVKPEGRPG V406
LKB1 (rat) EPQLSSKVKPEGRPG V406
LKB1 (pig) SVQLSAKSRAERRAS S312
R409
tKsRAEGRAPNPARk
1 0
LKB1 (human) tKsRAEGRAPNPARk R409
LKB1 iso2 (human) DLSGEEAsRPAPQ__ S399-p
LKB1 (mouse) SKVKPEGRPGTANPA R411
LKB1 (rat) SKVKPEGRPGAANPA R411
LKB1 (pig) AKSRAERRASATSNP R317
K416-ac
RAPNPARkACSASSk
1 0
LKB1 (human) RAPNPARkACSASSk K416-ac
LKB1 iso2 (human) gap -
LKB1 (mouse) GTANPARKVCSsNKI K420
LKB1 (rat) GAANPARKVCSSNKI K420
LKB1 (pig) ATSNPTRKACSASSK K327
S421
ARkACSASSkIRRLs
0 1
LKB1 (human) ARkACSASSkIRRLs S421
LKB1 iso2 (human) gap -
LKB1 (mouse) PARKVCSsNKIRRLs S424-p
LKB1 (rat) PARKVCSSNKIRRLs S424
LKB1 (pig) TRKACSASSKIRRLs S332
K423-ac
kACSASSkIRRLsAC
1 0
LKB1 (human) kACSASSkIRRLsAC K423-ac
LKB1 iso2 (human) gap -
LKB1 (mouse) RKVCSsNKIRRLsAC K426
LKB1 (rat) RKVCSSNKIRRLsAC K426
LKB1 (pig) KACSASSKIRRLsAC K334
S428-p
SSkIRRLsACkQQ__
Upstream
Downstream
33 5
LKB1 (human)
S428-p
LKB1 (mouse)
S431-p
Effects on Modified Protein
  • enzymatic activity, induced
  • intracellular localization
  • molecular association, regulation
  • phosphorylation
Effects on Biological Processes:
  • carcinogenesis, induced
  • carcinogenesis, inhibited
  • cell cycle regulation
  • cell growth, altered
  • cell motility, induced
  • signaling pathway regulation
Kinase, in vitro:
  • LKB1 (human)
  • PKCZ (human)
Putative in vivo kinases:
  • PKACA (human)
  • PKCZ (human)
Putative upstream phosphatases:
  • PPP2CA (human)
Regulatory protein:
  • EGFR (human)
  • IHPK1 (human)
  • IHPK2 (human)
  • LKB1 (human)
  • PKCZ (human)
Treatment
  • 2-deoxyglucose
  • acadesine
  • AG1478
  • atenolol
  • BAPTA-AM
  • colforsin
  • EGF
  • H-89
  • H2O2
  • ICI-118,551
  • leptin
  • metformin
  • NAC
  • nicotine
  • NNAL
  • NNK
  • okadaic_acid
  • ONOO(-)
  • palmitate
  • PD153035
  • PDTC
  • phenoxybenzamine
  • phorbol_ester
  • PKC-zeta_inhibitor
  • propranolol
  • PyST
  • resveratrol
  • S17834
  • simvastatin
  • Sin-1
  • siRNA
  • statin
  • STO-609
  • UV
  • yohimbine
LKB1 (human) SSkIRRLsACkQQ__ S428-p
LKB1 iso2 (human) gap -
LKB1 (mouse) sNKIRRLsACKQQ__ S431-p
LKB1 (rat) SNKIRRLsACKQQ__ S431-p
LKB1 (pig) SSKIRRLsACKQQ__ S339-p
K431-ac
IRRLsACkQQ_____
1 0
LKB1 (human) IRRLsACkQQ_____ K431-ac
LKB1 iso2 (human) gap -
LKB1 (mouse) IRRLsACKQQ_____ K434
LKB1 (rat) IRRLsACKQQ_____ K434
LKB1 (pig) IRRLsACKQQ_____ K342