Other Species / Isoforms
  IRE1 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
T49-p
LHAVSKRtGSIKWTL
0 1
IRE1 (human) LHAVSKRtGSIKWTL T49-p
IRE1 (mouse) LHAVSKRTGSIKWTL T51
K88-ub
SLYTLGSkNNEGLTk
0 1
IRE1 (human) SLYTLGSkNNEGLTk K88-ub
IRE1 (mouse) SLYTLGGKNNEGLTK K90
K95-ub
kNNEGLTkLPFTIPE
0 1
IRE1 (human) kNNEGLTkLPFTIPE K95-ub
IRE1 (mouse) KNNEGLTKLPFTIPE K97
T132-p
WYVIDLLtGEKQQTL
0 1
IRE1 (human) WYVIDLLtGEKQQTL T132-p
IRE1 (mouse) WYVIDLLTGEKQQTL T134
Y161-p
LYLGRTEyTITMyDT
0 1
IRE1 (human) LYLGRTEyTITMyDT Y161-p
IRE1 (mouse) LYLGRTEYTITMYDT Y163
Y166-p
TEyTITMyDTKTREL
0 2
IRE1 (human) TEyTITMyDTKTREL Y166-p
IRE1 (mouse) TEYTITMYDTKTREL Y168
Y179-p
ELRWNATyFDYAASL
0 1
IRE1 (human) ELRWNATyFDYAASL Y179-p
IRE1 (mouse) ELRWNATYFDYAASL Y181
T283-p
AKSKLTPtLYVGKyS
0 1
IRE1 (human) AKSKLTPtLYVGKyS T283-p
IRE1 (mouse) AKSKLTPTLYVGKYS T285
Y289-p
PtLYVGKySTSLYAS
0 1
IRE1 (human) PtLYVGKySTSLYAS Y289-p
IRE1 (mouse) PTLYVGKYSTSLYAS Y291
K374-ac
TPLSASTkMLERFPN
0 1
IRE1 (human) TPLSASTkMLERFPN K374-ac
IRE1 (mouse) TPLSASTKMLERFPN K376
K374-ub
TPLSASTkMLERFPN
0 1
IRE1 (human) TPLSASTkMLERFPN K374-ub
IRE1 (mouse) TPLSASTKMLERFPN K376
K485-ub
QFQKELEkIQLLQQQ
0 1
IRE1 (human) QFQKELEkIQLLQQQ K485-ub
IRE1 (mouse) QFQKELEKIQLLQQQ K487
S533-p
PSTSPRAsNHsLCSG
0 1
IRE1 (human) PSTSPRAsNHsLCSG S533-p
IRE1 (mouse) PSPSPRASNHSLHPS S533
S536-p
SPRAsNHsLCSGSSA
0 1
IRE1 (human) SPRAsNHsLCSGSSA S536-p
IRE1 (mouse) SPRASNHSLHPSSSA S536
S544-p
LCSGSSAsKAGsSPs
0 1
IRE1 (human) LCSGSSAsKAGsSPs S544-p
IRE1 (mouse) LHPSSSASRAGTSPs S544
S548-p
SSAsKAGsSPsLEQD
0 1
IRE1 (human) SSAsKAGsSPsLEQD S548-p
IRE1 (mouse) SSASRAGTSPsLEQD T548
S551-p
sKAGsSPsLEQDDGD
0 2
IRE1 (human) sKAGsSPsLEQDDGD S551-p
IRE1 (mouse) SRAGTSPsLEQDDED S551-p
Y628-p
EHPNVIRyFCTEkDR
Upstream
Downstream
1 0
Effects on Modified Protein
  • protein conformation
Kinase, in vitro:
  • IRE1 (human)
IRE1 (human) EHPNVIRyFCTEkDR Y628-p
IRE1 (mouse) EHPNVIRYFCTEKDR Y628
K633-ub
IRyFCTEkDRQFQYI
0 2
IRE1 (human) IRyFCTEkDRQFQYI K633-ub
IRE1 (mouse) IRYFCTEKDRQFQYI K633
K706-ub
PNAHGKIkAMISDFG
0 2
IRE1 (human) PNAHGKIkAMISDFG K706-ub
IRE1 (mouse) PNAHGRIkAMISDFG K706-ub
S724-p
KLAVGRHsFsRRsGV
Upstream
Downstream
18 2
Effects on Modified Protein
  • enzymatic activity, induced
Effects on Biological Processes:
  • RNA splicing, induced
  • apoptosis, induced
  • autophagy, induced
  • endocytosis, induced
  • transcription, altered
Regulatory protein:
  • ARMET (human)
  • CTH (human)
  • HSP70 (human)
  • IRE1 (human)
Treatment
  • 2-deoxyglucose
  • argimesna
  • carfilzomib
  • GLP-1
  • glucose
  • high-fat diet
  • insulin
  • KCl
  • thapsigargin
  • tolbutamide
  • tunicamycin
  • VER-155008
  • virus infection
IRE1 (human) KLAVGRHsFsRRsGV S724-p
IRE1 (mouse) KLAVGRHsFSRRsGV S724-p
S726-p
AVGRHsFsRRsGVPG
0 1
IRE1 (human) AVGRHsFsRRsGVPG S726-p
IRE1 (mouse) AVGRHsFSRRsGVPG S726
S729-p
RHsFsRRsGVPGTEG
Upstream
2 2
Treatment
  • SubAB
  • tunicamycin
IRE1 (human) RHsFsRRsGVPGTEG S729-p
IRE1 (mouse) RHsFSRRsGVPGTEG S729-p
K811
IARELIEKMIAMDPQ
0 1
IRE1 (human) IARELIEKMIAMDPQ K811
IRE1 (mouse) IARELIEkMIAMDPQ K811-ub
K851-ub
DVSDRIEkESLDGPI
0 1
IRE1 (human) DVSDRIEkESLDGPI K851-ub
IRE1 (mouse) DVSDRIEKEALDGPI K851
K860-ub
SLDGPIVkQLERGGR
0 1
IRE1 (human) SLDGPIVkQLERGGR K860-ub
IRE1 (mouse) ALDGPIVRQLERGGR R860
K871
RGGRAVVKMDWRENI
0 1
IRE1 (human) RGGRAVVKMDWRENI K871
IRE1 (mouse) RGGRAVVkMDWRENI K871-ub
T973-p
PEPQPPVtPDAL___
0 9
IRE1 (human) PEPQPPVtPDAL___ T973-p
IRE1 (mouse) TEPQPPVIPYAL___ I973