Other Species / Isoforms
  FLT3 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
P2
______MPALARDGG
0 1
FLT3 (human) ______MPALARDGG P2
FLT3 (mouse) ______MrALAQrSD R2-m1
R6
__MPALARDGGQLPL
0 1
FLT3 (human) __MPALARDGGQLPL R6
FLT3 (mouse) _MrALAQrSDRRLLL R7-m1
S18
LPLLVVFSAMIFGTI
0 1
FLT3 (human) LPLLVVFSAMIFGTI S18
FLT3 (mouse) LLLLVVLsVMILEtV S19-p
T24
FSAMIFGTITNQDLP
0 1
FLT3 (human) FSAMIFGTITNQDLP T24
FLT3 (mouse) LsVMILEtVtNQDLP T25-p
T26
AMIFGTITNQDLPVI
0 1
FLT3 (human) AMIFGTITNQDLPVI T26
FLT3 (mouse) VMILEtVtNQDLPVI T27-p
N43
VLINHKNNDSSVGKS
0 1
FLT3 (human) VLINHKNNDSSVGKS N43
FLT3 (mouse) VLISHENnGSSAGKP N44-ng
T163
FTVSIRNTLLyTLRR
0 1
FLT3 (human) FTVSIRNTLLyTLRR T163
FLT3 (mouse) FTVNVRDtQLYVLRR T164-p
Y166-p
SIRNTLLyTLRRPYF
0 1
FLT3 (human) SIRNTLLyTLRRPYF Y166-p
FLT3 (mouse) NVRDtQLYVLRRPYF Y167
T343-p
PSQSALVtIVEKGFI
0 1
FLT3 (human) PSQSALVtIVEKGFI T343-p
FLT3 (mouse) PSQSALVTILEKGFI T344
N351
IVEKGFINATNSSED
0 1
FLT3 (human) IVEKGFINATNSSED N351
FLT3 (mouse) ILEKGFInATSSQEE N352-ng
Y416-p
HKHQPGEyIFHAEND
0 1
FLT3 (human) HKHQPGEyIFHAEND Y416-p
FLT3 (mouse) HKNKPGEYIFYAEND Y417
Y572-p
KYKKQFRyESQLQMV
Downstream
2 0
Effects on Modified Protein
  • molecular association, regulation
FLT3 (human) KYKKQFRyESQLQMV Y572-p
FLT3 (mouse) KYKKQFRYESQLQMI Y573
Y589-p
TGSSDNEyFyVDFRE
Upstream
Downstream
6 1
FLT3 (human)
Y589-p
FLT3 (mouse)
Y590-p
Effects on Modified Protein
  • enzymatic activity, inhibited
  • molecular association, regulation
  • phosphorylation
Effects on Biological Processes:
  • cell growth, altered
Putative in vivo kinases:
  • FLT3 (human)
Treatment
  • FL
FLT3 (human) TGSSDNEyFyVDFRE Y589-p
FLT3 (mouse) TGPLDNEyFyVDFRD Y590-p
Y591-p
SSDNEyFyVDFREyE
Upstream
Downstream
13 0
FLT3 (human)
Y591-p
FLT3 (mouse)
Y592-p
Effects on Modified Protein
  • enzymatic activity, induced
  • molecular association, regulation
  • phosphorylation
Effects on Biological Processes:
  • cell growth, altered
Kinase, in vitro:
  • FLT3 (human)
Treatment
  • AG1296
  • FL
  • MLN-518
  • PKC412
FLT3 (human) SSDNEyFyVDFREyE Y591-p
FLT3 (mouse) PLDNEyFyVDFRDYE Y592-p
Y597-p
FyVDFREyEyDLkWE
Upstream
Downstream
2 0
Effects on Modified Protein
  • phosphorylation
Treatment
  • FL
FLT3 (human) FyVDFREyEyDLkWE Y597-p
FLT3 (mouse) FyVDFRDYEyDLKWE Y598
Y599-p
VDFREyEyDLkWEFP
Upstream
Downstream
6 2
Effects on Modified Protein
  • enzymatic activity, induced
  • molecular association, regulation
  • phosphorylation
Putative in vivo kinases:
  • FLT3 (human)
Treatment
  • FL
FLT3 (human) VDFREyEyDLkWEFP Y599-p
FLT3 (mouse) VDFRDYEyDLKWEFP Y600-p
K602-ub
REyEyDLkWEFPREN
0 1
FLT3 (human) REyEyDLkWEFPREN K602-ub
FLT3 (mouse) RDYEyDLKWEFPREN K603
K614-ub
RENLEFGkVLGSGAF
0 2
FLT3 (human) RENLEFGkVLGSGAF K614-ub
FLT3 (mouse) RENLEFGKVLGSGAF K615
K623-ub
LGSGAFGkVMNATAy
Upstream
0 1
Treatment
  • MG132
FLT3 (human) LGSGAFGkVMNATAy K623-ub
FLT3 (mouse) LGSGAFGRVMNATAy R624
Y630-p
kVMNATAyGISkTGV
0 45
FLT3 (human) kVMNATAyGISkTGV Y630-p
FLT3 (mouse) RVMNATAyGISKTGV Y631-p
K634-ub
ATAyGISkTGVSIQV
0 2
FLT3 (human) ATAyGISkTGVSIQV K634-ub
FLT3 (mouse) ATAyGISKTGVSIQV K635
K644-ub
VSIQVAVkMLKEKAD
0 1
FLT3 (human) VSIQVAVkMLKEKAD K644-ub
FLT3 (mouse) VSIQVAVKMLKEKAD K645
K719-ub
RTWTEIFkEHNFSFy
0 1
FLT3 (human) RTWTEIFkEHNFSFy K719-ub
FLT3 (mouse) RTWTEIFKEHNFSFy K720
Y726-p
kEHNFSFyPtFQSHP
Upstream
Downstream
2 7
Effects on Modified Protein
  • phosphorylation
Kinase, in vitro:
  • FLT3 (human)
Treatment
  • FL
FLT3 (human) kEHNFSFyPtFQSHP Y726-p
FLT3 (mouse) KEHNFSFyPtFQAHS Y727-p
T728-p
HNFSFyPtFQSHPNS
0 3
FLT3 (human) HNFSFyPtFQSHPNS T728-p
FLT3 (mouse) HNFSFyPtFQAHSNS T729-p
S759-p
ISGLHGNsFHSEDEI
0 1
FLT3 (human) ISGLHGNsFHSEDEI S759-p
FLT3 (mouse) LSGFNGNSIHSEDEI S760
Y768-p
HSEDEIEyENQkRLE
Upstream
Downstream
2 0
Effects on Modified Protein
  • molecular association, regulation
Effects on Biological Processes:
  • cell cycle regulation
Treatment
  • FL
FLT3 (human) HSEDEIEyENQkRLE Y768-p
FLT3 (mouse) HSEDEIEyENQKRLA Y769-p
K772-ub
EIEyENQkRLEEEED
0 1
FLT3 (human) EIEyENQkRLEEEED K772-ub
FLT3 (mouse) EIEyENQKRLAEEEE K773
Y793-p
EDLLCFAyQVAKGME
Upstream
Downstream
2 1
Effects on Modified Protein
  • molecular association, regulation
Treatment
  • FL
FLT3 (human) EDLLCFAyQVAKGME Y793-p
FLT3 (mouse) EDLLCFAyQVAKGME Y796-p
S840-p
ARDIMSDsNyVVRGN
0 1
FLT3 (human) ARDIMSDsNyVVRGN S840-p
FLT3 (mouse) ARDILSDSSyVVRGN S843
Y842-p
DIMSDsNyVVRGNAR
Upstream
Downstream
5 78
FLT3 (human)
Y842-p
FLT3 (mouse)
Y845-p
Effects on Modified Protein
  • phosphorylation
  • protein conformation
Effects on Biological Processes:
  • apoptosis, inhibited
  • cell growth, altered
Kinase, in vitro:
  • FLT3 (human)
Treatment
  • 2-deoxyglucose
  • FL
  • PKC412
FLT3 (human) DIMSDsNyVVRGNAR Y842-p
FLT3 (mouse) DILSDSSyVVRGNAR Y845-p
Y865
ESLFEGIYTIKSDVW
0 1
FLT3 (human) ESLFEGIYTIKSDVW Y865
FLT3 (mouse) ESLFEGIyTIKSDVW Y868-p
Y889
FSLGVNPYPGIPVDA
1 0
FLT3 (human) FSLGVNPYPGIPVDA Y889
FLT3 (mouse) FSLGVNPyPGIPVDA Y892-p
Y919
FYATEEIYIIMQSCW
1 0
FLT3 (human) FYATEEIYIIMQSCW Y919
FLT3 (mouse) FYATEGIyFVMQsCW Y922-p
S924
EIYIIMQSCWAFDSR
0 1
FLT3 (human) EIYIIMQSCWAFDSR S924
FLT3 (mouse) GIyFVMQsCWAFDSR S927-p
K932-ub
CWAFDSRkRPSFPNL
0 1
FLT3 (human) CWAFDSRkRPSFPNL K932-ub
FLT3 (mouse) CWAFDSRKRPSFPNL K935
Y955-p
ADAEEAMyQNVDGRV
Upstream
Downstream
5 16
Effects on Modified Protein
  • molecular association, regulation
  • phosphorylation
Effects on Biological Processes:
  • cell cycle regulation
Kinase, in vitro:
  • FLT3 (human)
Treatment
  • 2-deoxyglucose
  • FL
  • PKC412
FLT3 (human) ADAEEAMyQNVDGRV Y955-p
FLT3 (mouse) AEAEEAMyQNMGGNV Y958-p
T968-p
RVSECPHtyQNRRPF
0 1
FLT3 (human) RVSECPHtyQNRRPF T968-p
FLT3 (mouse) NVPEHPSIYQNRRPL I971
Y969-p
VSECPHtyQNRRPFS
Upstream
Downstream
3 18
FLT3 (human)
Y969-p
FLT3 (mouse)
Y972-p
Effects on Modified Protein
  • molecular association, regulation
Effects on Biological Processes:
  • cell cycle regulation
Kinase, in vitro:
  • FLT3 (human)
Treatment
  • 2-deoxyglucose
  • FL
  • PKC412
FLT3 (human) VSECPHtyQNRRPFS Y969-p
FLT3 (mouse) VPEHPSIYQNRRPLS Y972
-
gap
0 2
FLT3 (human) gap -
FLT3 (mouse) PLSREAGsEPPsPQA S984-p
S985
EMDLGLLSPQAQVED
0 2
FLT3 (human) EMDLGLLSPQAQVED S985
FLT3 (mouse) EAGsEPPsPQAQVKI S988-p
S993-p
PQAQVEDs_______
0 1
FLT3 (human) PQAQVEDs_______ S993-p
FLT3 (mouse) PQAQVKIHRERS___ H996