Y157-p
|
DQNKFLCyADTIHWQ
|
|
|
0
|
1
|
|
|
HER4 (human)
|
DQNKFLCyADTIHWQ
|
Y157-p
|
HER4 iso2 (human)
|
DQNKFLCYADTIHWQ
|
Y157
|
HER4 iso3 (human)
|
DQNKFLCYADTIHWQ
|
Y157
|
HER4 iso4 (human)
|
DQNKFLCYADTIHWQ
|
Y157
|
HER4 (mouse)
|
DQNKFLCYADTIHWQ
|
Y157
|
HER4 (rat)
|
DQNKFLCYADTIHWQ
|
Y157
|
|
S173-p
|
IVRNPWPsNLTLVST
|
|
|
0
|
1
|
|
|
HER4 (human)
|
IVRNPWPsNLTLVST
|
S173-p
|
HER4 iso2 (human)
|
IVRNPWPSNLTLVST
|
S173
|
HER4 iso3 (human)
|
IVRNPWPSNLTLVST
|
S173
|
HER4 iso4 (human)
|
IVRNPWPSNLTLVST
|
S173
|
HER4 (mouse)
|
IVRNPWPSnMTLVST
|
S173
|
HER4 (rat)
|
IVRNPWPSNMTLVST
|
S173
|
|
N174
|
VRNPWPsNLTLVSTN
|
|
|
0
|
1
|
|
|
HER4 (human)
|
VRNPWPsNLTLVSTN
|
N174
|
HER4 iso2 (human)
|
VRNPWPSNLTLVSTN
|
N174
|
HER4 iso3 (human)
|
VRNPWPSNLTLVSTN
|
N174
|
HER4 iso4 (human)
|
VRNPWPSNLTLVSTN
|
N174
|
HER4 (mouse)
|
VRNPWPSnMTLVSTn
|
N174-ng
|
HER4 (rat)
|
VRNPWPSNMTLVSTI
|
N174
|
|
N181
|
NLTLVSTNGsSGCGR
|
|
|
0
|
1
|
|
|
HER4 (human)
|
NLTLVSTNGsSGCGR
|
N181
|
HER4 iso2 (human)
|
NLTLVSTNGSSGCGR
|
N181
|
HER4 iso3 (human)
|
NLTLVSTNGSSGCGR
|
N181
|
HER4 iso4 (human)
|
NLTLVSTNGSSGCGR
|
N181
|
HER4 (mouse)
|
nMTLVSTnGSSGCGR
|
N181-ng
|
HER4 (rat)
|
NMTLVSTIGSSGCGR
|
I181
|
|
S183-p
|
TLVSTNGsSGCGRCH
|
|
|
0
|
1
|
|
|
HER4 (human)
|
TLVSTNGsSGCGRCH
|
S183-p
|
HER4 iso2 (human)
|
TLVSTNGSSGCGRCH
|
S183
|
HER4 iso3 (human)
|
TLVSTNGSSGCGRCH
|
S183
|
HER4 iso4 (human)
|
TLVSTNGSSGCGRCH
|
S183
|
HER4 (mouse)
|
TLVSTnGSSGCGRCH
|
S183
|
HER4 (rat)
|
TLVSTIGSSGCGRCH
|
S183
|
|
T327-p
|
IKMCKPCtDICPKAC
|
|
|
0
|
1
|
|
|
HER4 (human)
|
IKMCKPCtDICPKAC
|
T327-p
|
HER4 iso2 (human)
|
IKMCKPCTDICPKAC
|
T327
|
HER4 iso3 (human)
|
IKMCKPCTDICPKAC
|
T327
|
HER4 iso4 (human)
|
IKMCKPCTDICPKAC
|
T327
|
HER4 (mouse)
|
IKMCKPCTDICPKAC
|
T327
|
HER4 (rat)
|
IKMCKPCTDICPKAC
|
T327
|
|
N548
|
GEFREFENGSICVEC
|
|
|
0
|
1
|
|
|
HER4 (human)
|
GEFREFENGSICVEC
|
N548
|
HER4 iso2 (human)
|
GEFREFENGSICVEC
|
N548
|
HER4 iso3 (human)
|
GEFREFENGSICVEC
|
N548
|
HER4 iso4 (human)
|
GEFREFENGSICVEC
|
N548
|
HER4 (mouse)
|
GEFREFEnGSICVEC
|
N548-ng
|
HER4 (rat)
|
GEFREFENGSICVEC
|
N548
|
|
N576
|
CHGPGPDNCTKCSHF
|
|
|
0
|
1
|
|
|
HER4 (human)
|
CHGPGPDNCTKCSHF
|
N576
|
HER4 iso2 (human)
|
CHGPGPDNCTKCSHF
|
N576
|
HER4 iso3 (human)
|
CHGPGPDNCTKCSHF
|
N576
|
HER4 iso4 (human)
|
CHGPGPDNCTKCSHF
|
N576
|
HER4 (mouse)
|
CHGPGPDnCTKCSHF
|
N576-ng
|
HER4 (rat)
|
CHGPGPDNCTKCSHF
|
N576
|
|
T692
|
ALRRFLETELVEPLt
|
|
|
0
|
1
|
|
|
HER4 (human)
|
ALRRFLETELVEPLt
|
T692
|
HER4 iso2 (human)
|
ALRRFLETELVEPLT
|
T682
|
HER4 iso3 (human)
|
ALRRFLETELVEPLT
|
T692
|
HER4 iso4 (human)
|
ALRRFLETELVEPLT
|
T682
|
HER4 (mouse)
|
ALRRFLEtELVEPLt
|
T692-p
|
HER4 (rat)
|
ALRRFLETELVEPLT
|
T692
|
|
T699-p
|
TELVEPLtPSGTAPN
|
Upstream
|
Downstream
|
1
|
11
|
|
|
Effects on Modified Protein
- enzymatic activity, inhibited
- phosphorylation
|
Effects on Biological Processes:
- signaling pathway regulation
|
|
Putative in vivo kinases:
|
Treatment
|
|
HER4 (human)
|
TELVEPLtPSGTAPN
|
T699-p
|
HER4 iso2 (human)
|
TELVEPLTPSGTAPN
|
T689
|
HER4 iso3 (human)
|
TELVEPLTPSGTAPN
|
T699
|
HER4 iso4 (human)
|
TELVEPLTPSGTAPN
|
T689
|
HER4 (mouse)
|
tELVEPLtPsGtAPN
|
T699-p
|
HER4 (rat)
|
TELVEPLTPSGTAPN
|
T699
|
|
S701
|
LVEPLtPSGTAPNQA
|
|
|
0
|
1
|
|
|
HER4 (human)
|
LVEPLtPSGTAPNQA
|
S701
|
HER4 iso2 (human)
|
LVEPLTPSGTAPNQA
|
S691
|
HER4 iso3 (human)
|
LVEPLTPSGTAPNQA
|
S701
|
HER4 iso4 (human)
|
LVEPLTPSGTAPNQA
|
S691
|
HER4 (mouse)
|
LVEPLtPsGtAPNQA
|
S701-p
|
HER4 (rat)
|
LVEPLTPSGTAPNQA
|
S701
|
|
T703
|
EPLtPSGTAPNQAQL
|
|
|
0
|
2
|
|
|
HER4 (human)
|
EPLtPSGTAPNQAQL
|
T703
|
HER4 iso2 (human)
|
EPLTPSGTAPNQAQL
|
T693
|
HER4 iso3 (human)
|
EPLTPSGTAPNQAQL
|
T703
|
HER4 iso4 (human)
|
EPLTPSGTAPNQAQL
|
T693
|
HER4 (mouse)
|
EPLtPsGtAPNQAQL
|
T703-p
|
HER4 (rat)
|
EPLTPSGTAPNQAQL
|
T703
|
|
K714-ub
|
QAQLRILkETELKRV
|
|
|
0
|
2
|
|
|
HER4 (human)
|
QAQLRILkETELKRV
|
K714-ub
|
HER4 iso2 (human)
|
QAQLRILKETELKRV
|
K704
|
HER4 iso3 (human)
|
QAQLRILKETELKRV
|
K714
|
HER4 iso4 (human)
|
QAQLRILKETELKRV
|
K704
|
HER4 (mouse)
|
QAQLRILKETELKRV
|
K714
|
HER4 (rat)
|
QAQLRILKETELKRV
|
K714
|
|
K714-sm
|
QAQLRILkETELKRV
|
|
Downstream
|
1
|
0
|
|
|
Effects on Modified Protein
- intracellular localization
- molecular association, regulation
- phosphorylation
|
Effects on Biological Processes:
- cell differentiation, induced
- signaling pathway regulation
|
|
HER4 (human)
|
QAQLRILkETELKRV
|
K714-sm
|
HER4 iso2 (human)
|
QAQLRILKETELKRV
|
K704
|
HER4 iso3 (human)
|
QAQLRILKETELKRV
|
K714
|
HER4 iso4 (human)
|
QAQLRILKETELKRV
|
K704
|
HER4 (mouse)
|
QAQLRILKETELKRV
|
K714
|
HER4 (rat)
|
QAQLRILKETELKRV
|
K714
|
|
T731-p
|
LGSGAFGtVyKGIWV
|
|
|
0
|
7
|
|
|
HER4 (human)
|
LGSGAFGtVyKGIWV
|
T731-p
|
HER4 iso2 (human)
|
LGSGAFGTVYKGIWV
|
T721
|
HER4 iso3 (human)
|
LGSGAFGTVYKGIWV
|
T731
|
HER4 iso4 (human)
|
LGSGAFGTVYKGIWV
|
T721
|
HER4 (mouse)
|
LGSGAFGTVyKGIWV
|
T731
|
HER4 (rat)
|
LGSGAFGTVYKGIWV
|
T731
|
|
Y733-p
|
SGAFGtVyKGIWVPE
|
|
Downstream
|
1
|
159
|
|
|
Effects on Modified Protein
- molecular association, regulation
|
|
HER4 (human)
|
SGAFGtVyKGIWVPE
|
Y733-p
|
HER4 iso2 (human)
|
SGAFGTVYKGIWVPE
|
Y723
|
HER4 iso3 (human)
|
SGAFGTVYKGIWVPE
|
Y733
|
HER4 iso4 (human)
|
SGAFGTVYKGIWVPE
|
Y723
|
HER4 (mouse)
|
SGAFGTVyKGIWVPE
|
Y733-p
|
HER4 (rat)
|
SGAFGTVYKGIWVPE
|
Y733
|
|
K745-ub
|
VPEGETVkIPVAIKI
|
|
|
0
|
5
|
|
|
HER4 (human)
|
VPEGETVkIPVAIKI
|
K745-ub
|
HER4 iso2 (human)
|
VPEGETVKIPVAIKI
|
K735
|
HER4 iso3 (human)
|
VPEGETVKIPVAIKI
|
K745
|
HER4 iso4 (human)
|
VPEGETVKIPVAIKI
|
K735
|
HER4 (mouse)
|
VPEGETVkIPVAIKI
|
K745-ub
|
HER4 (rat)
|
VPEGETVKIPVAIKI
|
K745
|
|
K873-ac
|
RLLEGDEkEyNADGG
|
|
|
0
|
1
|
|
|
HER4 (human)
|
RLLEGDEkEyNADGG
|
K873-ac
|
HER4 iso2 (human)
|
RLLEGDEKEYNADGG
|
K863
|
HER4 iso3 (human)
|
RLLEGDEKEYNADGG
|
K873
|
HER4 iso4 (human)
|
RLLEGDEKEYNADGG
|
K863
|
HER4 (mouse)
|
RLLEGDEKEYNADGG
|
K873
|
HER4 (rat)
|
RLLEGDEKEYNADGG
|
K873
|
|
Y875-p
|
LEGDEkEyNADGGkM
|
|
Downstream
|
0
|
7
|
|
|
Effects on Modified Protein
- molecular association, regulation
|
|
HER4 (human)
|
LEGDEkEyNADGGkM
|
Y875-p
|
HER4 iso2 (human)
|
LEGDEKEYNADGGKM
|
Y865
|
HER4 iso3 (human)
|
LEGDEKEYNADGGKM
|
Y875
|
HER4 iso4 (human)
|
LEGDEKEYNADGGKM
|
Y865
|
HER4 (mouse)
|
LEGDEKEYNADGGKM
|
Y875
|
HER4 (rat)
|
LEGDEKEYNADGGKM
|
Y875
|
|
K881-ac
|
EyNADGGkMPIKWMA
|
|
|
0
|
1
|
|
|
HER4 (human)
|
EyNADGGkMPIKWMA
|
K881-ac
|
HER4 iso2 (human)
|
EYNADGGKMPIKWMA
|
K871
|
HER4 iso3 (human)
|
EYNADGGKMPIKWMA
|
K881
|
HER4 iso4 (human)
|
EYNADGGKMPIKWMA
|
K871
|
HER4 (mouse)
|
EYNADGGKMPIKWMA
|
K881
|
HER4 (rat)
|
EYNADGGKMPIKWMA
|
K881
|
|
K935-ub
|
EIPDLLEkGERLPQP
|
|
|
0
|
3
|
|
|
HER4 (human)
|
EIPDLLEkGERLPQP
|
K935-ub
|
HER4 iso2 (human)
|
EIPDLLEKGERLPQP
|
K925
|
HER4 iso3 (human)
|
EIPDLLEKGERLPQP
|
K935
|
HER4 iso4 (human)
|
EIPDLLEKGERLPQP
|
K925
|
HER4 (mouse)
|
EIPDLLEkGERLPQP
|
K935-ub
|
HER4 (rat)
|
EIPDLLEKGERLPQP
|
K935
|
|
Y984-p
|
MARDPQRyLVIQGDD
|
|
Downstream
|
1
|
0
|
|
|
|
Effects on Modified Protein
- molecular association, regulation
|
|
HER4 (human)
|
MARDPQRyLVIQGDD
|
Y984-p
|
HER4 iso2 (human)
|
MARDPQRYLVIQGDD
|
Y974
|
HER4 iso3 (human)
|
MARDPQRYLVIQGDD
|
Y984
|
HER4 iso4 (human)
|
MARDPQRYLVIQGDD
|
Y974
|
HER4 (mouse)
|
MARDPQRYLVIQGDD
|
Y984
|
HER4 (rat)
|
MARDPQRYLVIQGDD
|
Y984
|
|
S997
|
DDRMKLPSPNDSKFF
|
|
|
0
|
1
|
|
|
HER4 (human)
|
DDRMKLPSPNDSKFF
|
S997
|
HER4 iso2 (human)
|
DDRMKLPSPNDSKFF
|
S987
|
HER4 iso3 (human)
|
DDRMKLPSPNDSKFF
|
S997
|
HER4 iso4 (human)
|
DDRMKLPSPNDSKFF
|
S987
|
HER4 (mouse)
|
DDRMKLPsPNDSKFF
|
S997-p
|
HER4 (rat)
|
DDRMKLPSPNDSKFF
|
S997
|
|
Y1022-p
|
DMMDAEEyLVPQAFN
|
|
Downstream
|
2
|
0
|
|
|
Effects on Modified Protein
- molecular association, regulation
|
Effects on Biological Processes:
|
|
HER4 (human)
|
DMMDAEEyLVPQAFN
|
Y1022-p
|
HER4 iso2 (human)
|
DMMDAEEYLVPQAFN
|
Y1012
|
HER4 iso3 (human)
|
DMMDAEEYLVPQAFN
|
Y1022
|
HER4 iso4 (human)
|
DMMDAEEYLVPQAFN
|
Y1012
|
HER4 (mouse)
|
DMMDAEEYLVPQAFN
|
Y1022
|
HER4 (rat)
|
DMMDAEEYLVPQAFN
|
Y1022
|
|
Y1035-p
|
FNIPPPIyTSRARID
|
|
Downstream
|
0
|
1
|
|
|
Effects on Modified Protein
- molecular association, regulation
|
|
HER4 (human)
|
FNIPPPIyTSRARID
|
Y1035-p
|
HER4 iso2 (human)
|
FNIPPPIYTSRARID
|
Y1025
|
HER4 iso3 (human)
|
FNIPPPIYTSRARID
|
Y1035
|
HER4 iso4 (human)
|
FNIPPPIYTSRARID
|
Y1025
|
HER4 (mouse)
|
FNIPPPIYTSRTRID
|
Y1035
|
HER4 (rat)
|
FNIPPPIYTSRTRID
|
Y1035
|
|
S1043-p
|
TSRARIDsNRSEIGH
|
|
|
0
|
2
|
|
|
HER4 (human)
|
TSRARIDsNRSEIGH
|
S1043-p
|
HER4 iso2 (human)
|
TSRARIDSNRSEIGH
|
S1033
|
HER4 iso3 (human)
|
TSRARIDsNRNQFVY
|
S1043-p
|
HER4 iso4 (human)
|
TSRARIDsNRNQFVY
|
S1033-p
|
HER4 (mouse)
|
TSRTRIDSNRSEIGH
|
S1043
|
HER4 (rat)
|
TSRTRIDSNRSEIGH
|
S1043
|
|
S1051-p
|
NRSEIGHsPPPAyTP
|
Upstream
|
Downstream
|
1
|
0
|
|
|
Effects on Modified Protein
- enzymatic activity, inhibited
|
Effects on Biological Processes:
- signaling pathway regulation
|
|
Putative in vivo kinases:
|
Treatment
|
|
HER4 (human)
|
NRSEIGHsPPPAyTP
|
S1051-p
|
HER4 iso2 (human)
|
NRSEIGHSPPPAYTP
|
S1041
|
HER4 iso3 (human)
|
gap
|
-
|
HER4 iso4 (human)
|
gap
|
-
|
HER4 (mouse)
|
NRSEIGHSPPPAYTP
|
S1051
|
HER4 (rat)
|
NRSEIGHSPPPAYTP
|
S1051
|
|
Y1056-p
|
GHsPPPAyTPMSGNQ
|
Upstream
|
Downstream
|
3
|
2
|
|
|
Effects on Modified Protein
- activity, induced
- molecular association, regulation
|
Effects on Biological Processes:
|
|
|
HER4 (human)
|
GHsPPPAyTPMSGNQ
|
Y1056-p
|
HER4 iso2 (human)
|
GHSPPPAYTPMSGNQ
|
Y1046
|
HER4 iso3 (human)
|
gap
|
-
|
HER4 iso4 (human)
|
gap
|
-
|
HER4 (mouse)
|
GHSPPPAYTPMSGNQ
|
Y1056
|
HER4 (rat)
|
GHSPPPAYTPMSGSQ
|
Y1056
|
|
Y1066-p
|
MSGNQFVyRDGGFAA
|
|
|
0
|
1
|
|
|
HER4 (human)
|
MSGNQFVyRDGGFAA
|
Y1066-p
|
HER4 iso2 (human)
|
MSGNQFVYRDGGFAA
|
Y1056
|
HER4 iso3 (human)
|
sNRNQFVYRDGGFAA
|
Y1050
|
HER4 iso4 (human)
|
sNRNQFVYRDGGFAA
|
Y1040
|
HER4 (mouse)
|
MSGNQFVYQDGGFAT
|
Y1066
|
HER4 (rat)
|
MSGSQFVYQDGGFAT
|
Y1066
|
|
Y1081-p
|
EQGVSVPyRAPTSTI
|
|
Downstream
|
0
|
1
|
|
|
Effects on Modified Protein
- molecular association, regulation
|
|
HER4 (human)
|
EQGVSVPyRAPTSTI
|
Y1081-p
|
HER4 iso2 (human)
|
EQGVSVPYRAPTSTI
|
Y1071
|
HER4 iso3 (human)
|
EQGVSVPYRAPTSTI
|
Y1065
|
HER4 iso4 (human)
|
EQGVSVPYRAPTSTI
|
Y1055
|
HER4 (mouse)
|
QQGMPMPYRATTSTI
|
Y1081
|
HER4 (rat)
|
QQGMPMPYTATTSTI
|
Y1081
|
|
Y1128-p
|
EDSSTQRySADPTVF
|
|
Downstream
|
0
|
2
|
|
|
Effects on Modified Protein
- molecular association, regulation
|
|
HER4 (human)
|
EDSSTQRySADPTVF
|
Y1128-p
|
HER4 iso2 (human)
|
EDSSTQRYSADPTVF
|
Y1118
|
HER4 iso3 (human)
|
EDSSTQRYSADPTVF
|
Y1112
|
HER4 iso4 (human)
|
EDSSTQRYSADPTVF
|
Y1102
|
HER4 (mouse)
|
EDSSTQRYSADPTVF
|
Y1128
|
HER4 (rat)
|
EDSSTQRYSADPTVF
|
Y1128
|
|
S1140-p
|
TVFAPERsPRGELDE
|
|
|
0
|
1
|
|
|
HER4 (human)
|
TVFAPERsPRGELDE
|
S1140-p
|
HER4 iso2 (human)
|
TVFAPERSPRGELDE
|
S1130
|
HER4 iso3 (human)
|
TVFAPERSPRGELDE
|
S1124
|
HER4 iso4 (human)
|
TVFAPERSPRGELDE
|
S1114
|
HER4 (mouse)
|
TVFAPERNPRGELDE
|
N1140
|
HER4 (rat)
|
TVFAPERNPRAELDE
|
N1140
|
|
Y1150-p
|
GELDEEGyMTPMRDK
|
|
Downstream
|
0
|
6
|
|
|
Effects on Modified Protein
- molecular association, regulation
|
|
HER4 (human)
|
GELDEEGyMTPMRDK
|
Y1150-p
|
HER4 iso2 (human)
|
GELDEEGYMTPMRDK
|
Y1140
|
HER4 iso3 (human)
|
GELDEEGYMTPMRDK
|
Y1134
|
HER4 iso4 (human)
|
GELDEEGYMTPMRDK
|
Y1124
|
HER4 (mouse)
|
GELDEEGyMtPMHDK
|
Y1150-p
|
HER4 (rat)
|
AELDEEGYMTPMHDK
|
Y1150
|
|
T1152
|
LDEEGyMTPMRDKPK
|
|
|
0
|
3
|
|
|
HER4 (human)
|
LDEEGyMTPMRDKPK
|
T1152
|
HER4 iso2 (human)
|
LDEEGYMTPMRDKPK
|
T1142
|
HER4 iso3 (human)
|
LDEEGYMTPMRDKPK
|
T1136
|
HER4 iso4 (human)
|
LDEEGYMTPMRDKPK
|
T1126
|
HER4 (mouse)
|
LDEEGyMtPMHDKPK
|
T1152-p
|
HER4 (rat)
|
LDEEGYMTPMHDKPK
|
T1152
|
|
Y1162-p
|
RDKPKQEyLNPVEEN
|
Upstream
|
Downstream
|
3
|
2
|
|
|
Effects on Modified Protein
- enzymatic activity, induced
- molecular association, regulation
|
Effects on Biological Processes:
- apoptosis, inhibited
- cell growth, induced
- cell motility, induced
|
|
Kinase, in vitro:
|
Treatment
|
|
HER4 (human)
|
RDKPKQEyLNPVEEN
|
Y1162-p
|
HER4 iso2 (human)
|
RDKPKQEYLNPVEEN
|
Y1152
|
HER4 iso3 (human)
|
RDKPKQEYLNPVEEN
|
Y1146
|
HER4 iso4 (human)
|
RDKPKQEYLNPVEEN
|
Y1136
|
HER4 (mouse)
|
HDKPKQEyLNPVEEN
|
Y1162-p
|
HER4 (rat)
|
HDKPKQEYLNPVEEN
|
Y1162
|
|
Y1188-p
|
QALDNPEyHNASNGP
|
|
Downstream
|
2
|
1
|
|
|
Effects on Modified Protein
- molecular association, regulation
|
|
HER4 (human)
|
QALDNPEyHNASNGP
|
Y1188-p
|
HER4 iso2 (human)
|
QALDNPEYHNASNGP
|
Y1178
|
HER4 iso3 (human)
|
QALDNPEYHNASNGP
|
Y1172
|
HER4 iso4 (human)
|
QALDNPEYHNASNGP
|
Y1162
|
HER4 (mouse)
|
QALDNPEYHSASSGP
|
Y1188
|
HER4 (rat)
|
QALDNPEYHSASSGP
|
Y1188
|
|
Y1202-p
|
PPKAEDEyVNEPLyL
|
|
Downstream
|
1
|
2
|
|
|
Effects on Modified Protein
- molecular association, regulation
|
|
HER4 (human)
|
PPKAEDEyVNEPLyL
|
Y1202-p
|
HER4 iso2 (human)
|
PPKAEDEYVNEPLYL
|
Y1192
|
HER4 iso3 (human)
|
PPKAEDEYVNEPLYL
|
Y1186
|
HER4 iso4 (human)
|
PPKAEDEYVNEPLYL
|
Y1176
|
HER4 (mouse)
|
PPKAEDEYVNEPLYL
|
Y1202
|
HER4 (rat)
|
PPKAEDEYVNEPLYL
|
Y1202
|
|
Y1208-p
|
EyVNEPLyLNTFANT
|
|
Downstream
|
1
|
2
|
|
|
Effects on Modified Protein
- molecular association, regulation
|
|
HER4 (human)
|
EyVNEPLyLNTFANT
|
Y1208-p
|
HER4 iso2 (human)
|
EYVNEPLYLNTFANT
|
Y1198
|
HER4 iso3 (human)
|
EYVNEPLYLNTFANT
|
Y1192
|
HER4 iso4 (human)
|
EYVNEPLYLNTFANT
|
Y1182
|
HER4 (mouse)
|
EYVNEPLYLNTFANA
|
Y1208
|
HER4 (rat)
|
EYVNEPLYLNTFTNA
|
Y1208
|
|
Y1221-p
|
NTLGKAEyLKNNILS
|
|
Downstream
|
1
|
1
|
|
|
Effects on Modified Protein
- molecular association, regulation
|
|
HER4 (human)
|
NTLGKAEyLKNNILS
|
Y1221-p
|
HER4 iso2 (human)
|
NTLGKAEYLKNNILS
|
Y1211
|
HER4 iso3 (human)
|
NTLGKAEYLKNNILS
|
Y1205
|
HER4 iso4 (human)
|
NTLGKAEYLKNNILS
|
Y1195
|
HER4 (mouse)
|
NALGSAEYMKNSVLS
|
Y1221
|
HER4 (rat)
|
NALGNAEYMKNSLLS
|
Y1221
|
|
Y1242-p
|
KAFDNPDyWNHSLPP
|
|
Downstream
|
2
|
4
|
|
|
Effects on Modified Protein
- molecular association, regulation
|
|
HER4 (human)
|
KAFDNPDyWNHSLPP
|
Y1242-p
|
HER4 iso2 (human)
|
KAFDNPDYWNHSLPP
|
Y1232
|
HER4 iso3 (human)
|
KAFDNPDYWNHSLPP
|
Y1226
|
HER4 iso4 (human)
|
KAFDNPDYWNHSLPP
|
Y1216
|
HER4 (mouse)
|
KAFDNPDYWNHSLPP
|
Y1242
|
HER4 (rat)
|
KAFDNPDYWNHSLPP
|
Y1242
|
|
Y1258-p
|
STLQHPDyLQEySTk
|
|
Downstream
|
0
|
4
|
|
|
Effects on Modified Protein
- molecular association, regulation
|
|
HER4 (human)
|
STLQHPDyLQEySTk
|
Y1258-p
|
HER4 iso2 (human)
|
STLQHPDYLQEYSTK
|
Y1248
|
HER4 iso3 (human)
|
STLQHPDYLQEYSTK
|
Y1242
|
HER4 iso4 (human)
|
STLQHPDYLQEYSTK
|
Y1232
|
HER4 (mouse)
|
STLQHPDYLQEYSTK
|
Y1258
|
HER4 (rat)
|
STLQHPDYLQEYSTK
|
Y1258
|
|
Y1262-p
|
HPDyLQEySTkyFyK
|
|
|
0
|
2
|
|
|
HER4 (human)
|
HPDyLQEySTkyFyK
|
Y1262-p
|
HER4 iso2 (human)
|
HPDYLQEYSTKYFYK
|
Y1252
|
HER4 iso3 (human)
|
HPDYLQEYSTKYFYK
|
Y1246
|
HER4 iso4 (human)
|
HPDYLQEYSTKYFYK
|
Y1236
|
HER4 (mouse)
|
HPDYLQEYSTKYFYK
|
Y1262
|
HER4 (rat)
|
HPDYLQEYSTKYFYK
|
Y1262
|
|
K1265-ub
|
yLQEySTkyFyKQNG
|
|
|
0
|
1
|
|
|
HER4 (human)
|
yLQEySTkyFyKQNG
|
K1265-ub
|
HER4 iso2 (human)
|
YLQEYSTKYFYKQNG
|
K1255
|
HER4 iso3 (human)
|
YLQEYSTKYFYKQNG
|
K1249
|
HER4 iso4 (human)
|
YLQEYSTKYFYKQNG
|
K1239
|
HER4 (mouse)
|
YLQEYSTKYFYKQNG
|
K1265
|
HER4 (rat)
|
YLQEYSTKYFYKQNG
|
K1265
|
|
Y1266-p
|
LQEySTkyFyKQNGR
|
|
|
0
|
1
|
|
|
HER4 (human)
|
LQEySTkyFyKQNGR
|
Y1266-p
|
HER4 iso2 (human)
|
LQEYSTKYFYKQNGR
|
Y1256
|
HER4 iso3 (human)
|
LQEYSTKYFYKQNGR
|
Y1250
|
HER4 iso4 (human)
|
LQEYSTKYFYKQNGR
|
Y1240
|
HER4 (mouse)
|
LQEYSTKYFYKQNGR
|
Y1266
|
HER4 (rat)
|
LQEYSTKYFYKQNGR
|
Y1266
|
|
Y1268-p
|
EySTkyFyKQNGRIR
|
|
Downstream
|
1
|
1
|
|
|
Effects on Modified Protein
- molecular association, regulation
|
|
HER4 (human)
|
EySTkyFyKQNGRIR
|
Y1268-p
|
HER4 iso2 (human)
|
EYSTKYFYKQNGRIR
|
Y1258
|
HER4 iso3 (human)
|
EYSTKYFYKQNGRIR
|
Y1252
|
HER4 iso4 (human)
|
EYSTKYFYKQNGRIR
|
Y1242
|
HER4 (mouse)
|
EYSTKYFYKQNGRIR
|
Y1268
|
HER4 (rat)
|
EYSTKYFYKQNGRIR
|
Y1268
|
|
Y1284-p
|
IVAENPEyLSEFSLK
|
Upstream
|
Downstream
|
6
|
8
|
|
|
|
Effects on Modified Protein
- enzymatic activity, induced
- molecular association, regulation
|
Effects on Biological Processes:
- apoptosis, inhibited
- cell growth, induced
|
|
Kinase, in vitro:
|
Treatment
- lapatinib
- phorbol_ester
- Trametinib
|
|
HER4 (human)
|
IVAENPEyLSEFSLK
|
Y1284-p
|
HER4 iso2 (human)
|
IVAENPEYLSEFSLK
|
Y1274
|
HER4 iso3 (human)
|
IVAENPEYLSEFSLK
|
Y1268
|
HER4 iso4 (human)
|
IVAENPEYLSEFSLK
|
Y1258
|
HER4 (mouse)
|
IVAENPEyLSEFSLK
|
Y1284-p
|
HER4 (rat)
|
IVAENPEyLSEFSLK
|
Y1284-p
|
|
Y1301-p
|
TVLPPPPyRHRNTVV
|
|
|
0
|
1
|
|
|
HER4 (human)
|
TVLPPPPyRHRNTVV
|
Y1301-p
|
HER4 iso2 (human)
|
TVLPPPPYRHRNTVV
|
Y1291
|
HER4 iso3 (human)
|
TVLPPPPYRHRNTVV
|
Y1285
|
HER4 iso4 (human)
|
TVLPPPPYRHRNTVV
|
Y1275
|
HER4 (mouse)
|
TMLPPPPYRHRNTVV
|
Y1301
|
HER4 (rat)
|
TMLPPPPYRHRNTVV
|
Y1301
|
|