Other Species / Isoforms
  TRF2 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

  HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
G30
SQPRKRPGREGGEGA
0 1
TRF2 (human) SQPRKRPGREGGEGA G30
TRF2 (mouse) SQPRKRPsREGGEGG S30-p
TRF2 (rat) gap -
TRF2 iso2 (rat) gap -
R55-me
GSSDGSGrAAGrrAS
Downstream
1 0
Effects on Biological Processes:
  • cell cycle regulation
  • cell growth, altered
TRF2 (human) GSSDGSGrAAGrrAS R55-me
TRF2 (mouse) GSSDSSGRAASRRAS R58
TRF2 (rat) GSSDNGGRAANRRAS R13
TRF2 iso2 (rat) GSSDNGGRAANRRAS R13
R59-me
GSGrAAGrrASrSSG
Upstream
Downstream
1 0
Effects on Biological Processes:
  • cell cycle regulation
  • cell growth, altered
Regulatory protein:
  • PRMT6 (human)
Treatment
  • siRNA
TRF2 (human) GSGrAAGrrASrSSG R59-me
TRF2 (mouse) SSGRAASRRASRSGG R62
TRF2 (rat) NGGRAANRRASRSGG R17
TRF2 iso2 (rat) NGGRAANRRASRSGG R17
R60-me
SGrAAGrrASrSSGr
Downstream
1 0
Effects on Biological Processes:
  • cell cycle regulation
  • cell growth, altered
TRF2 (human) SGrAAGrrASrSSGr R60-me
TRF2 (mouse) SGRAASRRASRSGGR R63
TRF2 (rat) GGRAANRRASRSGGR R18
TRF2 iso2 (rat) GGRAANRRASRSGGR R18
R63-me
AAGrrASrSSGrArr
Downstream
1 0
Effects on Biological Processes:
  • cell cycle regulation
  • cell growth, altered
TRF2 (human) AAGrrASrSSGrArr R63-me
TRF2 (mouse) AASRRASRSGGRARR R66
TRF2 (rat) AANRRASRSGGRARR R21
TRF2 iso2 (rat) AANRRASRSGGRARR R21
R67-me
rASrSSGrArrGrHE
Downstream
1 0
Effects on Biological Processes:
  • cell cycle regulation
  • cell growth, altered
TRF2 (human) rASrSSGrArrGrHE R67-me
TRF2 (mouse) RASRSGGRARRGRHE R70
TRF2 (rat) RASRSGGRARRGRHE R25
TRF2 iso2 (rat) RASRSGGRARRGRHE R25
R69-me
SrSSGrArrGrHEPG
Downstream
1 0
Effects on Biological Processes:
  • cell cycle regulation
  • cell growth, altered
TRF2 (human) SrSSGrArrGrHEPG R69-me
TRF2 (mouse) SRSGGRARRGRHEPG R72
TRF2 (rat) SRSGGRARRGRHEPG R27
TRF2 iso2 (rat) SRSGGRARRGRHEPG R27
R70-me
rSSGrArrGrHEPGL
Downstream
1 0
Effects on Biological Processes:
  • cell cycle regulation
  • cell growth, altered
TRF2 (human) rSSGrArrGrHEPGL R70-me
TRF2 (mouse) RSGGRARRGRHEPGL R73
TRF2 (rat) RSGGRARRGRHEPGL R28
TRF2 iso2 (rat) RSGGRARRGRHEPGL R28
R70-m1
rSSGrArrGrHEPGL
0 1
TRF2 (human) rSSGrArrGrHEPGL R70-m1
TRF2 (mouse) RSGGRARRGRHEPGL R73
TRF2 (rat) RSGGRARRGRHEPGL R28
TRF2 iso2 (rat) RSGGRARRGRHEPGL R28
R72-me
SGrArrGrHEPGLGG
Downstream
1 0
Effects on Biological Processes:
  • cell cycle regulation
  • cell growth, altered
TRF2 (human) SGrArrGrHEPGLGG R72-me
TRF2 (mouse) GGRARRGRHEPGLGG R75
TRF2 (rat) GGRARRGRHEPGLGG R30
TRF2 iso2 (rat) GGRARRGRHEPGLGG R30
R72-m1
SGrArrGrHEPGLGG
0 1
TRF2 (human) SGrArrGrHEPGLGG R72-m1
TRF2 (mouse) GGRARRGRHEPGLGG R75
TRF2 (rat) GGRARRGRHEPGLGG R30
TRF2 iso2 (rat) GGRARRGRHEPGLGG R30
K135-ub
LLVRPLGkEHTVSRL
0 1
TRF2 (human) LLVRPLGkEHTVSRL K135-ub
TRF2 (mouse) LLVRPLGKEHTVSRL K138
TRF2 (rat) LLVRPLGKEHTVSRL K93
TRF2 iso2 (rat) LLVRPLGKEHTVSRL K93
K211-ac
VIICIKNkEFEkASK
0 13
TRF2 (human) VIICIKNkEFEkASK K211-ac
TRF2 (mouse) VIICIKNkEFEkASK K214-ac
TRF2 (rat) VIICIKNkEFEKASK K169-ac
TRF2 iso2 (rat) VIICIKNKEFEKASK K169
K215-ac
IKNkEFEkASKILKK
0 11
TRF2 (human) IKNkEFEkASKILKK K215-ac
TRF2 (mouse) IKNkEFEkASKILKK K218-ac
TRF2 (rat) IKNkEFEKASKILKK K173
TRF2 iso2 (rat) IKNKEFEKASKILKK K173
T229-p
KHMSKDPttQkLRND
0 3
TRF2 (human) KHMSKDPttQkLRND T229-p
TRF2 (mouse) KYMSKDPTTQKLRTD T232
TRF2 (rat) KYMSKDPTTQKVRTD T187
TRF2 iso2 (rat) KYMSKDPTTQKVRTD T187
T230-p
HMSKDPttQkLRNDL
Upstream
Downstream
3 1
Effects on Modified Protein
  • intracellular localization
Regulatory protein:
  • HMGA2 (human)
Treatment
  • caffeine
  • etoposide
  • ionizing_radiation
  • wortmannin
view more >
TRF2 (human) HMSKDPttQkLRNDL T230-p
TRF2 (mouse) YMSKDPTTQKLRTDL T233
TRF2 (rat) YMSKDPTTQKVRTDL T188
TRF2 iso2 (rat) YMSKDPTTQKVRTDL T188
K232-ub
SKDPttQkLRNDLLN
0 1
TRF2 (human) SKDPttQkLRNDLLN K232-ub
TRF2 (mouse) SKDPTTQKLRTDLLN K235
TRF2 (rat) SKDPTTQKVRTDLLN K190
TRF2 iso2 (rat) SKDPTTQKVRTDLLN K190
K283-ub
PYLLTMAkKALksEs
0 1
TRF2 (human) PYLLTMAkKALksEs K283-ub
TRF2 (mouse) PYLLTMAKKALKSES K286
TRF2 (rat) PYLLTMAKKALRSES K241
TRF2 iso2 (rat) PYLLTMAKKALRSES K241
K287-sm
TMAkKALksEsAASS
0 1
TRF2 (human) TMAkKALksEsAASS K287-sm
TRF2 (mouse) TMAKKALKSESAASS K290
TRF2 (rat) TMAKKALRSESAASS R245
TRF2 iso2 (rat) TMAKKALRSESAASS R245
S288-p
MAkKALksEsAASST
0 1
TRF2 (human) MAkKALksEsAASST S288-p
TRF2 (mouse) MAKKALKSESAASST S291
TRF2 (rat) MAKKALRSESAASST S246
TRF2 iso2 (rat) MAKKALRSESAASST S246
S290-p
kKALksEsAASSTGK
0 1
TRF2 (human) kKALksEsAASSTGK S290-p
TRF2 (mouse) KKALKSESAASSTMR S293
TRF2 (rat) KKALRSESAASSTMK S248
TRF2 iso2 (rat) KKALRSESAASSTMK S248
R312-m2
GPVEKPPrEPArQLR
0 1
TRF2 (human) GPVEKPPrEPArQLR R312-m2
TRF2 (mouse) EPVEKPLREPPSRQP R313
TRF2 (rat) EPVEKPLREPPRQPR R268
TRF2 iso2 (rat) EPVEKPLREPPRQPR R268
R316-m2
KPPrEPArQLRNPPt
0 1
TRF2 (human) KPPrEPArQLRNPPt R316-m2
TRF2 (mouse) PLREPPSRQPQNPPA R318
TRF2 (rat) KPLREPPRQPRNPPT R272
TRF2 iso2 (rat) KPLREPPRQPRNPPT R272
T323-p
rQLRNPPttIGMMTL
0 1
TRF2 (human) rQLRNPPttIGMMTL T323-p
TRF2 (mouse) RQPQNPPATIGIRTL A325
TRF2 (rat) RQPRNPPTTIGLRTV T279
TRF2 iso2 (rat) RQPRNPPTTIGLRTV T279
T324-p
QLRNPPttIGMMTLK
0 1
TRF2 (human) QLRNPPttIGMMTLK T324-p
TRF2 (mouse) QPQNPPATIGIRTLK T326
TRF2 (rat) QPRNPPTTIGLRTVK T280
TRF2 iso2 (rat) QPRNPPTTIGLRTVK T280
K335-ac
MTLKAAFkTLsGAQD
Downstream
1 2
Effects on Modified Protein
  • molecular association, regulation
  • protein stabilization
Effects on Biological Processes:
  • cell cycle regulation
  • cell growth, altered
TRF2 (human) MTLKAAFkTLsGAQD K335-ac
TRF2 (mouse) RTLKAAFKALSTAQD K337
TRF2 (rat) RTVKAAFkALSTAQD K291-ac
TRF2 iso2 (rat) RTVKAAFKALSTAQD K291
K335-ub
MTLKAAFkTLsGAQD
0 3
TRF2 (human) MTLKAAFkTLsGAQD K335-ub
TRF2 (mouse) RTLKAAFKALSTAQD K337
TRF2 (rat) RTVKAAFKALSTAQD K291
TRF2 iso2 (rat) RTVKAAFKALSTAQD K291
S338-p
KAAFkTLsGAQDSEA
0 1
TRF2 (human) KAAFkTLsGAQDSEA S338-p
TRF2 (mouse) KAAFKALSTAQDSEA S340
TRF2 (rat) KAAFkALSTAQDSEA S294
TRF2 iso2 (rat) KAAFKALSTAQDSEA S294
K349-ub
DSEAAFAkLDQKDLV
0 2
TRF2 (human) DSEAAFAkLDQKDLV K349-ub
TRF2 (mouse) DSEAAFAKLDQKDLV K351
TRF2 (rat) DSEAAFAKLDQKDLV K305
TRF2 iso2 (rat) DSEAAFAKLDQKDLS K305
L362
LVLPTQALPAsPALK
0 7
TRF2 (human) LVLPTQALPAsPALK L362
TRF2 (mouse) LVLANLAsPssPAHK S364-p
TRF2 (rat) LVLPNLAsPSSPtHK S318-p
TRF2 iso2 (rat) gap -
A364
LPTQALPAsPALKNK
0 5
TRF2 (human) LPTQALPAsPALKNK A364
TRF2 (mouse) LANLAsPssPAHKHK S366-p
TRF2 (rat) LPNLAsPSSPtHKNK S320
TRF2 iso2 (rat) gap -
S365-p
PTQALPAsPALKNKR
Upstream
Downstream
3 158
Effects on Modified Protein
  • molecular association, regulation
  • protein stabilization
Effects on Biological Processes:
  • cell cycle regulation
  • cell growth, induced
Kinase, in vitro:
  • CDK2 (human)
  • ERK2 (human)
Putative in vivo kinases:
  • CDK2 (human)
  • ERK2 (human)
Putative upstream phosphatases:
  • PPP6C (human)
Regulatory protein:
  • PPP4C (human)
Treatment
  • LRRK2-IN-1
  • nocodazole
  • seliciclib
  • siRNA
  • U0126
view more >
TRF2 (human) PTQALPAsPALKNKR S365-p
TRF2 (mouse) ANLAsPssPAHKHKR S367-p
TRF2 (rat) PNLAsPSSPtHKNKR S321
TRF2 iso2 (rat) gap -
A367
QALPAsPALKNKRPR
0 1
TRF2 (human) QALPAsPALKNKRPR A367
TRF2 (mouse) LAsPssPAHKHKRPR A369
TRF2 (rat) LAsPSSPtHKNKRPR T323-p
TRF2 iso2 (rat) gap -
S390
PADGEGGSELQPKNK
0 1
TRF2 (human) PADGEGGSELQPKNK S390
TRF2 (mouse) PAEGEGGsDRQPRNs S392-p
TRF2 (rat) PAEGEGGSERQPRNN S346
TRF2 iso2 (rat) gap -
K397
SELQPKNKRMTISRL
0 15
TRF2 (human) SELQPKNKRMTISRL K397
TRF2 (mouse) sDRQPRNsPMTIsRL S399-p
TRF2 (rat) SERQPRNNRMTISRL N353
TRF2 iso2 (rat) gap -
S402
KNKRMTISRLVLEED
0 1
TRF2 (human) KNKRMTISRLVLEED S402
TRF2 (mouse) RNsPMTIsRLLLEED S404-p
TRF2 (rat) RNNRMTISRLVLEED S358
TRF2 iso2 (rat) gap -
S410-p
RLVLEEDsQStEPSA
0 5
TRF2 (human) RLVLEEDsQStEPSA S410-p
TRF2 (mouse) RLLLEEDsQstEPsP S412-p
TRF2 (rat) RLVLEEDSQSSEPSP S366
TRF2 iso2 (rat) gap -
S412
VLEEDsQStEPSAGL
0 1
TRF2 (human) VLEEDsQStEPSAGL S412
TRF2 (mouse) LLEEDsQstEPsPGL S414-p
TRF2 (rat) VLEEDSQSSEPSPDL S368
TRF2 iso2 (rat) gap -
T413-p
LEEDsQStEPSAGLN
0 2
TRF2 (human) LEEDsQStEPSAGLN T413-p
TRF2 (mouse) LEEDsQstEPsPGLN T415-p
TRF2 (rat) LEEDSQSSEPSPDLN S369
TRF2 iso2 (rat) gap -
S416
DsQStEPSAGLNSsQ
0 1
TRF2 (human) DsQStEPSAGLNSsQ S416
TRF2 (mouse) DsQstEPsPGLNssH S418-p
TRF2 (rat) DSQSSEPSPDLNSSR S372
TRF2 iso2 (rat) gap -
S421
EPSAGLNSsQEAAsA
0 1
TRF2 (human) EPSAGLNSsQEAAsA S421
TRF2 (mouse) EPsPGLNssHKAMsA S423-p
TRF2 (rat) EPSPDLNSSRQALSA S377
TRF2 iso2 (rat) gap -
S422-p
PSAGLNSsQEAAsAP
0 3
TRF2 (human) PSAGLNSsQEAAsAP S422-p
TRF2 (mouse) PsPGLNssHKAMsAS S424-p
TRF2 (rat) PSPDLNSSRQALSAs S378
TRF2 iso2 (rat) gap -
S427-p
NSsQEAAsAPPSkPT
0 3
TRF2 (human) NSsQEAAsAPPSkPT S427-p
TRF2 (mouse) NssHKAMsASKPRAL S429-p
TRF2 (rat) NSSRQALSAsPSKPR S383
TRF2 iso2 (rat) gap -
P429
sQEAAsAPPSkPTVL
0 1
TRF2 (human) sQEAAsAPPSkPTVL P429
TRF2 (mouse) gap -
TRF2 (rat) SRQALSAsPSKPRAL S385-p
TRF2 iso2 (rat) gap -
K432-ub
AAsAPPSkPTVLNQP
0 1
TRF2 (human) AAsAPPSkPTVLNQP K432-ub
TRF2 (mouse) HKAMsASKPRALNQP K432
TRF2 (rat) ALSAsPSKPRALNQP K388
TRF2 iso2 (rat) gap -
K444-ub
NQPLPGEkNPKVPKG
0 1
TRF2 (human) NQPLPGEkNPKVPKG K444-ub
TRF2 (mouse) NQPHPGEKKPKASKD K444
TRF2 (rat) NQPHTGEKNPKASKD K400
TRF2 iso2 (rat) gap -
S456-p
PKGKWNSsNGVEEKE
0 1
TRF2 (human) PKGKWNSsNGVEEKE S456-p
TRF2 (mouse) SKDKWNSPNGLEEKE P456
TRF2 (rat) SKDKWNSPNGLEEKE P412
TRF2 iso2 (rat) gap -
V466
VEEKETWVEEDELFQ
0 2
TRF2 (human) VEEKETWVEEDELFQ V466
TRF2 (mouse) LEEKEVWLEEDQLFE L466
TRF2 (rat) LEEKEVWsEEDQLFE S422-p
TRF2 iso2 (rat) gap -
N485
PDEDSTTNITKkQKW
0 1
TRF2 (human) PDEDSTTNITKkQKW N485
TRF2 (mouse) PGEDRSSsLTRKQKW S484-p
TRF2 (rat) PGEDKSSNLARKQKW N440
TRF2 iso2 (rat) gap -
K489-ac
STTNITKkQKWTVEE
1 0
TRF2 (human) STTNITKkQKWTVEE K489-ac
TRF2 (mouse) RSSsLTRKQKWTIEE K488
TRF2 (rat) KSSNLARKQKWTIEE K444
TRF2 iso2 (rat) gap -
K530-ac
NRTAVMIkDRWRTMK
1 0
TRF2 (human) NRTAVMIkDRWRTMK K530-ac
TRF2 (mouse) NRTAVMIKDRWRTMK K529
TRF2 (rat) NRTAVMIKDRWRTMK K485
TRF2 iso2 (rat) gap -