Other Species / Isoforms
  CDK4 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

  HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
Y17-p
AEIGVGAyGTVYkAR
Upstream
1 5
Kinase, in vitro:
  • LYN (human)
  • Src (human)
  • Yes (human)
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Putative in vivo kinases:
  • Yes (human)
Treatment
  • PP2
  • SU6656
  • vanadate
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CDK4 (human) AEIGVGAyGTVYkAR Y17-p
CDK4 (mouse) AEIGVGAYGTVYKAR Y17
CDK4 (rat) AEIGVGAYGTVYKAR Y17
K22-ub
GAyGTVYkARDPHSG
0 4
CDK4 (human) GAyGTVYkARDPHSG K22-ub
CDK4 (mouse) GAYGTVYKARDPHSG K22
CDK4 (rat) GAYGTVYKARDPHSG K22
K35
SGHFVALKSVRVPNG
0 1
CDK4 (human) SGHFVALKSVRVPNG K35
CDK4 (mouse) SGHFVALKSVRVPNG K35
CDK4 (rat) SGHFVALkSVRVPNG K35-ac
K35-ub
SGHFVALkSVRVPNG
0 3
CDK4 (human) SGHFVALkSVRVPNG K35-ub
CDK4 (mouse) SGHFVALKSVRVPNG K35
CDK4 (rat) SGHFVALKSVRVPNG K35
R101-m1
EHVDQDLrTYLDkAP
0 1
CDK4 (human) EHVDQDLrTYLDkAP R101-m1
CDK4 (mouse) EHIDQDLRTYLDKAP R101
CDK4 (rat) EHIDQDLRTYLDKAP R101
K106-ub
DLrTYLDkAPPPGLP
0 4
CDK4 (human) DLrTYLDkAPPPGLP K106-ub
CDK4 (mouse) DLRTYLDKAPPPGLP K106
CDK4 (rat) DLRTYLDKAPPPGLP K106
K118-ub
GLPAETIkDLMRQFL
0 2
CDK4 (human) GLPAETIkDLMRQFL K118-ub
CDK4 (mouse) GLPVETIKDLMRQFL K118
CDK4 (rat) GLPVETIKDLMRQFL K118
K142-ub
CIVHRDLkPENILVT
0 4
CDK4 (human) CIVHRDLkPENILVT K142-ub
CDK4 (mouse) CIVHRDLKPENILVT K142
CDK4 (rat) CIVHRDLKPENILVT K142
K155-ub
VTSGGTVkLADFGLA
0 2
CDK4 (human) VTSGGTVkLADFGLA K155-ub
CDK4 (mouse) VTSNGTVKLADFGLA K155
CDK4 (rat) VTSNGTVKLADFGLA K155
T172-p
YSYQMALtPVVVTLW
Upstream
Downstream
11 5
Effects on Modified Protein
  • enzymatic activity, induced
Effects on Biological Processes:
  • cell cycle regulation
Kinase, in vitro:
  • CDK7 (human)
  • JNK1 (human)
  • JNK2 (human)
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Regulatory protein:
  • p21Cip1 (human)
Treatment
  • 1NM-PP1
  • colforsin
  • EGF
  • IFN-alpha
  • IFN-gamma
  • insulin
  • MG132
  • PD0332991
  • rapamycin
  • seliciclib
  • serum
  • TGF-beta
  • TSH
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CDK4 (human) YSYQMALtPVVVTLW T172-p
CDK4 (mouse) YSYQMALtPVVVTLW T172-p
CDK4 (rat) YSYQMALTPVVVTLW T172
K211-ub
FAEMFRRkPLFCGNS
0 3
CDK4 (human) FAEMFRRkPLFCGNS K211-ub
CDK4 (mouse) FAEMFRRKPLFCGNS K211
CDK4 (rat) FAEMFRRKPLFCGNS K211
P250
SLPRGAFPPRGPRPV
0 1
CDK4 (human) SLPRGAFPPRGPRPV P250
CDK4 (mouse) SLPRGAFAPRGPRPV A250
CDK4 (rat) SLPRGAFsPRGPRPV S250-p
K297-ub
LQHSYLHkDEGNPE_
0 4
CDK4 (human) LQHSYLHkDEGNPE_ K297-ub
CDK4 (mouse) LQHSYLHKEEsDAE_ K297
CDK4 (rat) LQHSYLHKEEsDPE_ K297
G300
SYLHkDEGNPE____
0 22
CDK4 (human) SYLHkDEGNPE____ G300
CDK4 (mouse) SYLHKEEsDAE____ S300-p
CDK4 (rat) SYLHKEEsDPE____ S300-p