Other Species / Isoforms
  Snail1 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
S11-p
SFLVRKPsDPNRKPN
Upstream
Downstream
4 0
Effects on Modified Protein
  • acetylation
  • activity, induced
  • activity, inhibited
  • intracellular localization
  • molecular association, regulation
  • protein degradation
  • protein stabilization
Effects on Biological Processes:
  • carcinogenesis, altered
  • carcinogenesis, induced
  • cell growth, induced
  • transcription, altered
  • transcription, induced
Kinase, in vitro:
  • PKACA (human)
  • PRKD1 (human)
Putative in vivo kinases:
  • PRKD1 (human)
Regulatory protein:
  • RHOA (human)
Treatment
  • bryostatin_1
  • CID755673
  • siRNA
  • TGF-beta
Snail1 (human) SFLVRKPsDPNRKPN S11-p
Snail1 (mouse) SFLVRKPSDPRRKPN S11
S82-p
ASLRLQEsPRVAELT
Upstream
Downstream
3 0
Effects on Modified Protein
  • intracellular localization
  • protein stabilization
Effects on Biological Processes:
  • carcinogenesis, induced
  • cell motility, induced
Kinase, in vitro:
  • ERK2 (human)
Putative in vivo kinases:
  • ERK2 (human)
Treatment
  • collagen_I
  • PD98059
  • siRNA
Snail1 (human) ASLRLQEsPRVAELT S82-p
Snail1 (mouse) ATLPLRESPKAVELT S82
S90-p
PRVAELTsLsDEDsG
0 1
Snail1 (human) PRVAELTsLsDEDsG S90-p
Snail1 (mouse) PKAVELTSLSDEDSG S90
S92-p
VAELTsLsDEDsGKG
Upstream
Downstream
2 5
Effects on Modified Protein
  • activity, inhibited
  • molecular association, regulation
  • protein degradation
Effects on Biological Processes:
  • carcinogenesis, inhibited
  • transcription, altered
  • transcription, inhibited
Kinase, in vitro:
  • CK2A1 (human)
  • CK2B (human)
Putative in vivo kinases:
  • CK2A1 (human)
  • CK2B (human)
Treatment
  • siRNA
  • TBB
Snail1 (human) VAELTsLsDEDsGKG S92-p
Snail1 (mouse) AVELTSLSDEDSGkS S92
S96-p
TsLsDEDsGKGsQPP
Upstream
Downstream
4 1
Effects on Modified Protein
  • intracellular localization
  • protein degradation
  • ubiquitination
Effects on Biological Processes:
  • cell motility, altered
  • transcription, altered
Kinase, in vitro:
  • GSK3B (human)
Phosphatases, in vitro:
  • CTDSP1 (human)
Putative in vivo kinases:
  • GSK3B (human)
Putative upstream phosphatases:
  • CTDSP1 (human)
Snail1 (human) TsLsDEDsGKGsQPP S96-p
Snail1 (mouse) TSLSDEDSGkSSQPP S96
K98
LsDEDsGKGsQPPsP
1 0
Snail1 (human) LsDEDsGKGsQPPsP K98
Snail1 (mouse) LSDEDSGkSSQPPSP K98-ub
S100-p
DEDsGKGsQPPsPPs
Upstream
Downstream
4 0
Effects on Modified Protein
  • intracellular localization
  • protein degradation
  • ubiquitination
Effects on Biological Processes:
  • cell motility, altered
  • transcription, altered
Kinase, in vitro:
  • GSK3B (human)
Phosphatases, in vitro:
  • CTDSP1 (human)
Putative in vivo kinases:
  • GSK3B (human)
Putative upstream phosphatases:
  • CTDSP1 (human)
Snail1 (human) DEDsGKGsQPPsPPs S100-p
Snail1 (mouse) DEDSGkSSQPPSPPS S100
S104-p
GKGsQPPsPPsPAPs
Upstream
Downstream
6 0
Effects on Modified Protein
  • activity, induced
  • intracellular localization
  • protein degradation
  • protein stabilization
  • ubiquitination
Effects on Biological Processes:
  • carcinogenesis, induced
  • cell motility, induced
  • transcription, altered
Kinase, in vitro:
  • CK1E (human)
  • DYRK2 (human)
  • ERK2 (human)
  • GSK3B (human)
Putative in vivo kinases:
  • ERK2 (human)
  • GSK3B (human)
Regulatory protein:
  • DYRK2 (human)
  • P38A (human)
Treatment
  • collagen_I
  • lithium
  • PD98059
  • SB203580
  • siRNA
Snail1 (human) GKGsQPPsPPsPAPs S104-p
Snail1 (mouse) GkSSQPPSPPSPAPS S104
S107-p
sQPPsPPsPAPssFS
Upstream
Downstream
6 1
Effects on Modified Protein
  • activity, induced
  • enzymatic activity, induced
  • intracellular localization
  • molecular association, regulation
  • phosphorylation
  • protein degradation
  • protein stabilization
  • ubiquitination
Effects on Biological Processes:
  • carcinogenesis, induced
  • cell motility, altered
  • cell motility, induced
  • signaling pathway regulation
  • transcription, altered
  • transcription, induced
Kinase, in vitro:
  • CK1E (human)
  • GSK3B (human)
  • P38A (human)
Phosphatases, in vitro:
  • CTDSP1 (human)
Putative in vivo kinases:
  • GSK3B (human)
  • P38A (human)
Putative upstream phosphatases:
  • CTDSP1 (human)
Regulatory protein:
  • MKK6 (human)
Treatment
  • cycloheximide
  • EGF
  • lithium
  • MG132
  • SB203580
  • siRNA
Snail1 (human) sQPPsPPsPAPssFS S107-p
Snail1 (mouse) SQPPSPPSPAPSSFS S107
S111-p
sPPsPAPssFSsTSV
Upstream
Downstream
2 0
Effects on Modified Protein
  • intracellular localization
Effects on Biological Processes:
  • cell motility, altered
  • transcription, altered
Kinase, in vitro:
  • GSK3B (human)
Phosphatases, in vitro:
  • CTDSP1 (human)
Putative in vivo kinases:
  • GSK3B (human)
Putative upstream phosphatases:
  • CTDSP1 (human)
Snail1 (human) sPPsPAPssFSsTSV S111-p
Snail1 (mouse) SPPSPAPSSFSSTSA S111
S112-gl
PPsPAPssFSsTSVs
Downstream
1 1
Effects on Modified Protein
  • phosphorylation
  • protein stabilization
Effects on Biological Processes:
  • cell motility, induced
  • transcription, inhibited
Snail1 (human) PPsPAPssFSsTSVs S112-gl
Snail1 (mouse) PPSPAPSSFSSTSAS S112
S115-p
PAPssFSsTSVsSLE
Upstream
Downstream
2 0
Effects on Modified Protein
  • intracellular localization
Effects on Biological Processes:
  • cell motility, altered
  • transcription, altered
Kinase, in vitro:
  • GSK3B (human)
Phosphatases, in vitro:
  • CTDSP1 (human)
Putative in vivo kinases:
  • GSK3B (human)
Putative upstream phosphatases:
  • CTDSP1 (human)
Snail1 (human) PAPssFSsTSVsSLE S115-p
Snail1 (mouse) PAPSSFSSTSASSLE S115
S119-p
sFSsTSVsSLEAEAY
Upstream
Downstream
2 0
Effects on Modified Protein
  • intracellular localization
Effects on Biological Processes:
  • cell motility, altered
  • transcription, altered
Kinase, in vitro:
  • GSK3B (human)
Phosphatases, in vitro:
  • CTDSP1 (human)
Putative in vivo kinases:
  • GSK3B (human)
Putative upstream phosphatases:
  • CTDSP1 (human)
Snail1 (human) sFSsTSVsSLEAEAY S119-p
Snail1 (mouse) SFSSTSASSLEAEAF S119
K137
PGLGQVPKQLAQLSE
1 0
Snail1 (human) PGLGQVPKQLAQLSE K137
Snail1 (mouse) PGLGQLPkQLARLSV K137-ub
K187-ac
CVCGTCGkAFSRPWL
Upstream
Downstream
1 0
Effects on Biological Processes:
  • transcription, induced
Treatment
  • siRNA
Snail1 (human) CVCGTCGkAFSRPWL K187-ac
Snail1 (mouse) CVCTTCGKAFSRPWL K187
T203-p
QGHVRTHtGEkPFSC
Upstream
Downstream
3 1
Effects on Modified Protein
  • activity, induced
  • intracellular localization
  • protein stabilization
Effects on Biological Processes:
  • carcinogenesis, induced
  • cell cycle regulation
  • cell motility, altered
  • transcription, induced
Kinase, in vitro:
  • LATS2 (human)
Putative in vivo kinases:
  • LATS2 (human)
Regulatory protein:
  • LATS2 (human)
  • MST2 (human)
  • SAV1 (human)
Treatment
  • high_cell_density
  • nocodazole
Snail1 (human) QGHVRTHtGEkPFSC T203-p
Snail1 (mouse) QGHVRTHTGEKPFSC T203
K206-ub
VRTHtGEkPFSCPHC
Downstream
1 0
Effects on Modified Protein
  • protein stabilization
Snail1 (human) VRTHtGEkPFSCPHC K206-ub
Snail1 (mouse) VRTHTGEKPFSCSHC K206
K234-ub
LQTHSDVkkYQCQAC
Downstream
1 0
Effects on Modified Protein
  • protein stabilization
Snail1 (human) LQTHSDVkkYQCQAC K234-ub
Snail1 (mouse) LQTHSDVKRYQCQAC K234
K235-ub
QTHSDVkkYQCQACA
Downstream
1 0
Effects on Modified Protein
  • protein stabilization
Snail1 (human) QTHSDVkkYQCQACA K235-ub
Snail1 (mouse) QTHSDVKRYQCQACA R235
S246-p
QACARTFsRMsLLHK
Upstream
Downstream
3 0
Effects on Modified Protein
  • intracellular localization
Effects on Biological Processes:
  • carcinogenesis, induced
  • transcription, altered
  • transcription, inhibited
Kinase, in vitro:
  • PAK1 (human)
Putative in vivo kinases:
  • PAK1 (human)
Treatment
  • ionizing_radiation
  • siRNA
Snail1 (human) QACARTFsRMsLLHK S246-p
Snail1 (mouse) QACARTFSRMSLLHK S246
S249-p
ARTFsRMsLLHKHQE
Upstream
Downstream
1 0
Effects on Modified Protein
  • molecular association, regulation
  • protein degradation
  • ubiquitination
Effects on Biological Processes:
  • carcinogenesis, inhibited
  • signaling pathway regulation
Kinase, in vitro:
  • PKCZ (human)
Putative in vivo kinases:
  • PKCZ (human)
Regulatory protein:
  • PAR3 (human)
Treatment
  • PZ09
  • siRNA
Snail1 (human) ARTFsRMsLLHKHQE S249-p
Snail1 (mouse) ARTFSRMSLLHKHQE S249
K234-sm
LQTHSDVkkYQCQAC
1 0
Snail1 (human) LQTHSDVkkYQCQAC K234-sm
Snail1 (mouse) LQTHSDVKRYQCQAC K234