Other Species / Isoforms
  AMPKA2 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
S165
FGLSNMMsDGEFLRt
0 5
AMPKA2 (human) FGLSNMMsDGEFLRt S165
AMPKA2 (mouse) FGLSNMMsDGEFLRt S165
AMPKA2 (rat) FGLSNMMSDGEFLRt S165
AMPKA2 (pig) FGLSNMMSDGEFLRt S165
T172
sDGEFLRtsCGsPNy
Upstream
Downstream
147 45
AMPKA2 (human)
T172
AMPKA2 (mouse)
T172
AMPKA2 (rat)
T172
Effects on Modified Protein
  • activity, induced
  • enzymatic activity, induced
  • intracellular localization
  • phosphorylation
  • protein degradation
Effects on Biological Processes:
  • apoptosis, induced
  • apoptosis, inhibited
  • autophagy, induced
  • carcinogenesis, inhibited
  • cell cycle regulation
  • cell growth, inhibited
  • cytoskeletal reorganization
  • signaling pathway regulation
  • transcription, altered
  • transcription, inhibited
Kinase, in vitro:
  • CAMKK2 (human)
  • LKB1 (human)
  • TAK1 (human)
Phosphatases, in vitro:
  • PPP2CA (human)
Putative in vivo kinases:
  • ATM (human)
  • CAMKK2 (human)
  • PLK1 (human)
  • TAK1 (human)
Regulatory protein:
  • ADIPOR1 (human)
  • ATF-4 (human)
  • ATM (human)
  • CAMKK2 (human)
  • CENTG1 (human)
  • DDIT4 (human)
  • Epac1 (human)
  • FAK (human)
  • Fyn (human)
  • HMOX1 (human)
  • IDH1 (human)
  • IL6 (mouse)
  • LKB1 (human)
  • Myc (human)
  • Nogo (human)
  • PDE4A (human)
  • PKACA (human)
  • PKD1 (human)
  • RFX7 (human)
  • RMP (human)
  • SESN2 (human)
  • SIRT1 (human)
  • SMS2 (human)
  • Src (human)
  • TAB1 (human)
  • Yes (human)
Treatment
  • 2-APB
  • 2-deoxyglucose
  • 2-hydroxyestradiol
  • 2-methoxyestradiol
  • 5-iodotubercidin
  • A-769662
  • A769662
  • ABT
  • acadesine
  • AdipoRon
  • adriamycin
  • angiotensin_2
  • antibody
  • Artesunate
  • BAPTA-AM
  • BI2536
  • bisindolylmaleimide
  • BMS-754807
  • CCCP
  • cell_detachment
  • chrysin
  • cobalt
  • compound_C
  • cpTOME
  • dasatinib
  • estradiol
  • exercise
  • exercise training
  • faslodex
  • fluorouracil
  • glucagon
  • glucose
  • glucose_starvation
  • Go_6983
  • H-89
  • H2O2
  • hemin
  • high-fat diet
  • high_cell_density
  • high_glucose
  • hypoxia
  • insulin
  • ischemia
  • lapatinib
  • LH
  • low_glucose
  • LXA4
  • LY294002
  • MDL12330A
  • metformin
  • Naringenin
  • naringin
  • neratinib
  • nicotinamide
  • nicotine
  • nilotinib
  • NKH_477
  • nocodazole
  • nutlin-3A
  • oligomycin
  • ONOO(-)
  • palbociclib
  • PD98059
  • PGE2a
  • phenformin
  • PKI
  • PP2
  • resveratrol
  • Ro_41-0960
  • rolipram
  • ryanodine
  • S-valproate
  • S17834
  • salinomycin
  • saracatinib
  • SCH772984
  • seliciclib
  • siRNA
  • SKI-606
  • sorafenib
  • splitomicin
  • starvation_medium
  • STO-609
  • terbinafine
  • terbutaline
  • TNF
  • U73122
  • vildagliptin
  • virus infection
AMPKA2 (human) sDGEFLRtsCGsPNy T172
AMPKA2 (mouse) sDGEFLRtsCGsPNY T172
AMPKA2 (rat) SDGEFLRtsCGSPNY T172
AMPKA2 (pig) SDGEFLRtSCGSPNY T172
S173
DGEFLRtsCGsPNyA
Upstream
2 19
Treatment
  • antibody
  • glucagon
  • metformin
AMPKA2 (human) DGEFLRtsCGsPNyA S173
AMPKA2 (mouse) DGEFLRtsCGsPNYA S173
AMPKA2 (rat) DGEFLRtsCGSPNYA S173
AMPKA2 (pig) DGEFLRtSCGSPNYA S173
S176
FLRtsCGsPNyAAPE
Upstream
0 18
Treatment
  • nocodazole
  • thymidine
AMPKA2 (human) FLRtsCGsPNyAAPE S176
AMPKA2 (mouse) FLRtsCGsPNYAAPE S176
AMPKA2 (rat) FLRtsCGSPNYAAPE S176
AMPKA2 (pig) FLRtSCGSPNYAAPE S176
Y179
tsCGsPNyAAPEVIS
Upstream
Downstream
1 3
Effects on Modified Protein
  • enzymatic activity, inhibited
  • phosphorylation
Effects on Biological Processes:
  • apoptosis, induced
  • autophagy, inhibited
  • signaling pathway regulation
Kinase, in vitro:
  • Src (human)
Putative in vivo kinases:
  • Src (human)
Regulatory protein:
  • Fyn (human)
  • Yes (human)
Treatment
  • SKI-606
AMPKA2 (human) tsCGsPNyAAPEVIS Y179
AMPKA2 (mouse) tsCGsPNYAAPEVIS Y179
AMPKA2 (rat) tsCGSPNYAAPEVIS Y179
AMPKA2 (pig) tSCGSPNYAAPEVIS Y179
Y232
KIRGGVFyIPEYLNR
0 1
AMPKA2 (human) KIRGGVFyIPEYLNR Y232
AMPKA2 (mouse) KIRGGVFYIPDYLNR Y232
AMPKA2 (rat) KIRGGVFYIPEYLNR Y232
AMPKA2 (pig) KIRGGVFYIPEYLNR Y232
T258
VDPLKRATIKDIREH
1 1
AMPKA2 (human) VDPLKRATIKDIREH T258
AMPKA2 (mouse) VDPLKRATIKDIREH T258
AMPKA2 (rat) VDPLKRAtIKDIREH T258
AMPKA2 (pig) VDPLKRATIKDIREH T258
S310
TESEVMNSLYSGDPQ
0 1
AMPKA2 (human) TESEVMNSLYSGDPQ S310
AMPKA2 (mouse) TESEVMNsLYSGDPQ S310
AMPKA2 (rat) TESEVMNSLYSGDPQ S310
AMPKA2 (pig) TESEVMNSLYSGDPQ S310
Y324
QDQLAVAyHLIIDNR
0 1
AMPKA2 (human) QDQLAVAyHLIIDNR Y324
AMPKA2 (mouse) QDQLAVAYHLIIDNR Y324
AMPKA2 (rat) QDQLAVAYHLIIDNR Y324
AMPKA2 (pig) QDQLAVAYHLVIDNR Y324
S377
MPPLIADsPKARCPL
Upstream
0 28
Treatment
  • ischemia
  • MG132_withdrawal
  • nocodazole
  • thymidine
AMPKA2 (human) MPPLIADsPKARCPL S377
AMPKA2 (mouse) MPPLIADsPKARCPL S377
AMPKA2 (rat) MPPLIADsPKARCPL S377
AMPKA2 (pig) MPPLIADSPKARCPL S377
Y436
EWKVVNAyHLRVRRK
Upstream
Downstream
1 0
Effects on Modified Protein
  • enzymatic activity, inhibited
Effects on Biological Processes:
  • autophagy, inhibited
Kinase, in vitro:
  • Fyn (human)
Putative in vivo kinases:
  • Fyn (human)
AMPKA2 (human) EWKVVNAyHLRVRRK Y436
AMPKA2 (mouse) EWKVVNAYHLRVRRK Y436
AMPKA2 (rat) EWKVVNAYHLRVRRK Y436
AMPKA2 (pig) EWKVVNAYHLRVRRK Y436
S481
DEVVEQRsGsstPQR
0 6
AMPKA2 (human) DEVVEQRsGsstPQR S481
AMPKA2 (mouse) DEVVEQRsGSstPQR S481
AMPKA2 (rat) DEVVEQRSGSSTPQR S481
AMPKA2 (pig) DEVLEQRSGSSTPQR S481
S483
VVEQRsGsstPQRsC
0 1
AMPKA2 (human) VVEQRsGsstPQRsC S483
AMPKA2 (mouse) VVEQRsGSstPQRSC S483
AMPKA2 (rat) VVEQRSGSSTPQRSC S483
AMPKA2 (pig) VLEQRSGSSTPQRSC S483
S484
VEQRsGsstPQRsCs
Upstream
1 2
Treatment
  • tamoxifen
AMPKA2 (human) VEQRsGsstPQRsCs S484
AMPKA2 (mouse) VEQRsGSstPQRSCs S484
AMPKA2 (rat) VEQRSGSSTPQRSCs S484
AMPKA2 (pig) LEQRSGSSTPQRSCS S484
T485
EQRsGsstPQRsCsA
1 2
AMPKA2 (human) EQRsGsstPQRsCsA T485
AMPKA2 (mouse) EQRsGSstPQRSCsA T485
AMPKA2 (rat) EQRSGSSTPQRSCsA T485
AMPKA2 (pig) EQRSGSSTPQRSCSA T485
S489
GsstPQRsCsAAGLH
0 1
AMPKA2 (human) GsstPQRsCsAAGLH S489
AMPKA2 (mouse) GSstPQRSCsAAGLH S489
AMPKA2 (rat) GSSTPQRSCsAAGLH S489
AMPKA2 (pig) GSSTPQRSCSAAGLH S489
S491
stPQRsCsAAGLHRP
Upstream
Downstream
12 13
AMPKA2 (human)
S491
AMPKA2 (rat)
S491
Effects on Biological Processes:
  • autophagy, altered
Treatment
  • acadesine
  • Akt_inhibitor_VIII
  • antibody
  • H-89
  • LH
  • NKH_477
  • PD184352
  • PKI
  • tamoxifen
  • VEGF
AMPKA2 (human) stPQRsCsAAGLHRP S491
AMPKA2 (mouse) stPQRSCsAAGLHRA S491
AMPKA2 (rat) STPQRSCsAAGLHRP S491
AMPKA2 (pig) STPQRSCSAAGLHRP S491
S500
AGLHRPRssFDSTTA
0 3
AMPKA2 (human) AGLHRPRssFDSTTA S500
AMPKA2 (mouse) AGLHRARssFDSSTA S500
AMPKA2 (rat) AGLHRPRSSVDSSTA S500
AMPKA2 (pig) AGLHRPRSSLDSVTA S500
S501
GLHRPRssFDSTTAE
0 2
AMPKA2 (human) GLHRPRssFDSTTAE S501
AMPKA2 (mouse) GLHRARssFDSSTAE S501
AMPKA2 (rat) GLHRPRSSVDSSTAE S501
AMPKA2 (pig) GLHRPRSSLDSVTAE S501
S509
FDSTTAEsHsLSGsL
0 1
AMPKA2 (human) FDSTTAEsHsLSGsL S509
AMPKA2 (mouse) FDSSTAENHSLSGSL N509
AMPKA2 (rat) VDSSTAENHSLSGSL N509
AMPKA2 (pig) LDSVTAESHSLSGSL S509
S511
STTAEsHsLSGsLTG
0 1
AMPKA2 (human) STTAEsHsLSGsLTG S511
AMPKA2 (mouse) SSTAENHSLSGSLTG S511
AMPKA2 (rat) SSTAENHSLSGSLTG S511
AMPKA2 (pig) SVTAESHSLSGSLSG S511
S515
EsHsLSGsLTGSLtG
0 2
AMPKA2 (human) EsHsLSGsLTGSLtG S515
AMPKA2 (mouse) ENHSLSGSLTGSLTG S515
AMPKA2 (rat) ENHSLSGSLTGSLTG S515
AMPKA2 (pig) ESHSLSGSLSGSLTG S515
T521
GsLTGSLtGStLSsV
0 1
AMPKA2 (human) GsLTGSLtGStLSsV T521
AMPKA2 (mouse) GSLTGSLTGSTLSSA T521
AMPKA2 (rat) GSLTGSLTGSTLSSA T521
AMPKA2 (pig) GSLSGSLTGSMLPSV T521
T524
TGSLtGStLSsVSPR
0 1
AMPKA2 (human) TGSLtGStLSsVSPR T524
AMPKA2 (mouse) TGSLTGSTLSSASPR T524
AMPKA2 (rat) TGSLTGSTLSSASPR T524
AMPKA2 (pig) SGSLTGSMLPSVPPR M524
S527
LtGStLSsVSPRLGs
0 1
AMPKA2 (human) LtGStLSsVSPRLGs S527
AMPKA2 (mouse) LTGSTLSSASPRLGS S527
AMPKA2 (rat) LTGSTLSSASPRLGS S527
AMPKA2 (pig) LTGSMLPSVPPRLGS S527
S534
sVSPRLGsHTMDFFE
0 1
AMPKA2 (human) sVSPRLGsHTMDFFE S534
AMPKA2 (mouse) SASPRLGSHTMDFFE S534
AMPKA2 (rat) SASPRLGSHTMDFFE S534
AMPKA2 (pig) SVPPRLGSHTMDFFE S534