Other Species / Isoforms
  Tyk2 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

  HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
T67
IAHKVGItPPCFNLF
0 1
Tyk2 (human) IAHKVGItPPCFNLF T67
Tyk2 (mouse) IAHKVGITPPCLNLF T72
Tyk2 (rat) IAHKVGITPPCLNLF T72
Y292
QAEGEPCyIRDSGVA
Upstream
1 1499
Kinase, in vitro:
  • Tyk2 (human)
Regulatory protein:
  • FGFR1 (human)
Treatment
  • antibody
  • ephrin_B1
  • ephrin_B2
  • HGF
  • IFN-alpha
view more >
Tyk2 (human) QAEGEPCyIRDSGVA Y292
Tyk2 (mouse) QPERDPCyIQNSGQT Y295
Tyk2 (rat) QPERDPCYIQNSGQT Y297
S339
EVNKEEGssGSSGRN
0 1
Tyk2 (human) EVNKEEGssGSSGRN S339
Tyk2 (mouse) HPLQTQESERGNSRG S337
Tyk2 (rat) RPLQTQDSERGHSRG S339
S340
VNKEEGssGSSGRNP
0 1
Tyk2 (human) VNKEEGssGSSGRNP S340
Tyk2 (mouse) PLQTQESERGNSRGN E338
Tyk2 (rat) PLQTQDSERGHSRGN E340
S406
DNKCLELsLPSRAAA
0 1
Tyk2 (human) DNKCLELsLPSRAAA S406
Tyk2 (mouse) DNKCLLLCLCSQAEA C405
Tyk2 (rat) DNKCLLLCLCSQAEA C407
S415
PSRAAALsFVSLVDG
0 1
Tyk2 (human) PSRAAALsFVSLVDG S415
Tyk2 (mouse) CSQAEALSFVALVDG S414
Tyk2 (rat) CSQAEALSFVALVDG S416
Y423
FVSLVDGyFRLTADS
0 2
Tyk2 (human) FVSLVDGyFRLTADS Y423
Tyk2 (mouse) FVALVDGYFRLTADS Y422
Tyk2 (rat) FVALVDGYFRLTADS Y424
Y433
LTADSSHyLCHEVAP
0 36
Tyk2 (human) LTADSSHyLCHEVAP Y433
Tyk2 (mouse) LTADSSHyLCHEVAP Y432
Tyk2 (rat) LTADSSHYLCHEVAP Y434
S491
ILTVAQRsQAPDGMQ
0 1
Tyk2 (human) ILTVAQRsQAPDGMQ S491
Tyk2 (mouse) ILTVAHRNPAFSNGP N490
Tyk2 (rat) ILTVAHRNPASRNGP N492
S499
QAPDGMQsLRLRKFP
Upstream
0 10
Treatment
  • nocodazole
  • thymidine
Tyk2 (human) QAPDGMQsLRLRKFP S499
Tyk2 (mouse) AFSNGPRGLRLRKFP G499
Tyk2 (rat) ASRNGPRGLRLRKFP G501
S525
GWGRSFPSVRELGAA
0 3
Tyk2 (human) GWGRSFPSVRELGAA S525
Tyk2 (mouse) GWGRSFAsLGDLRLA S525
Tyk2 (rat) GWGRSFDSLGDLRQA S527
S577
SPRTLNLsQLsFHRV
0 4
Tyk2 (human) SPRTLNLsQLsFHRV S577
Tyk2 (mouse) HTRPLNLSQLSFHRV S577
Tyk2 (rat) HTRPLNLSQLSFHRV S579
S580
TLNLsQLsFHRVDQK
0 6
Tyk2 (human) TLNLsQLsFHRVDQK S580
Tyk2 (mouse) PLNLSQLSFHRVHQD S580
Tyk2 (rat) PLNLSQLSFHRVHQD S582
Y604
QGTRTNVyEGRLRVE
0 2
Tyk2 (human) QGTRTNVyEGRLRVE Y604
Tyk2 (mouse) QGTRTNVyEGLLRVG Y604
Tyk2 (rat) QGTRTNVYEGLLSVG Y606
S613
GRLRVEGsGDPEEGK
0 1
Tyk2 (human) GRLRVEGsGDPEEGK S613
Tyk2 (mouse) gap -
Tyk2 (rat) gap -
S720
VVAQQLAsALsYLEN
0 2
Tyk2 (human) VVAQQLAsALsYLEN S720
Tyk2 (mouse) VVAQQLASALSYLED S717
Tyk2 (rat) VVAQQLASALSYLED S719
S723
QQLAsALsYLENKNL
0 2
Tyk2 (human) QQLAsALsYLENKNL S723
Tyk2 (mouse) QQLASALSYLEDKNL S720
Tyk2 (rat) QQLASALSYLEDKNL S722
Y827
PSEKEHFyQRQHRLP
0 32
Tyk2 (human) PSEKEHFyQRQHRLP Y827
Tyk2 (mouse) PSEKERFYTKKHQLP Y824
Tyk2 (rat) PSEKERFYTKKHQLP Y826
Y851
LTSQCLTyEPTQRPS
0 1
Tyk2 (human) LTSQCLTyEPTQRPS Y851
Tyk2 (mouse) LTRQCLTYEPAQRPS Y848
Tyk2 (rat) LTRQCLSYEPAQRPS Y850
S884
VLTVNPDsPASDPTV
Upstream
0 5
Treatment
  • nocodazole
  • thymidine
Tyk2 (human) VLTVNPDsPASDPTV S884
Tyk2 (mouse) TSAVNSDSPASDPTV S881
Tyk2 (rat) TSTVNSDSPASDPTV S883
Y914
HFGKVSLYCYDPTND
0 1
Tyk2 (human) HFGKVSLYCYDPTND Y914
Tyk2 (mouse) HFGKVSLyCYDPTND Y911
Tyk2 (rat) HFGKVSLYCYDPNND Y913
S942
DCGPQHRSGWKQEID
0 1
Tyk2 (human) DCGPQHRSGWKQEID S942
Tyk2 (mouse) GCGPQLRsGWQREIE S939
Tyk2 (rat) GCGPQLRSGWQREIE S941
Y1054
AVPEGHEyyRVREDG
Upstream
Downstream
10 60
Tyk2 (human)
Y1054
Tyk2 (mouse)
Y1051
Tyk2 (rat)
Y1053
Effects on Modified Protein
  • enzymatic activity, induced
Effects on Biological Processes:
  • signaling pathway regulation
Kinase, in vitro:
  • Tyk2 (human)
Regulatory protein:
  • IFNAR1 (human)
Treatment
  • 2-deoxyglucose
  • BMS-986165
  • cryptotanshinone
  • IFN-alpha
  • IFN-beta
  • virus infection
view more >
Tyk2 (human) AVPEGHEyyRVREDG Y1054
Tyk2 (mouse) AVPEGHEyyRVREDG Y1051
Tyk2 (rat) AVPEGHEYYRVREDG Y1053
Y1055
VPEGHEyyRVREDGD
Upstream
Downstream
8 7
Tyk2 (human)
Y1055
Tyk2 (mouse)
Y1052
Tyk2 (rat)
Y1054
Effects on Modified Protein
  • enzymatic activity, induced
Effects on Biological Processes:
  • signaling pathway regulation
Kinase, in vitro:
  • Tyk2 (human)
Regulatory protein:
  • IFNAR1 (human)
Treatment
  • BMS-986165
  • cryptotanshinone
  • IFN-alpha
  • IFN-beta
  • virus infection
view more >
Tyk2 (human) VPEGHEyyRVREDGD Y1055
Tyk2 (mouse) VPEGHEyyRVREDGD Y1052
Tyk2 (rat) VPEGHEYYRVREDGD Y1054