mTOR (human)

LTP

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

HTP

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

K42-ub

ETRAKAAkELQHYVT

mTOR (human)	ETRAKAAkELQHYVT	K42-ub
mTOR (mouse)	ETRAKAAKELQHYVT	K42
mTOR (rat)	ETRAKAAKELQHYVT	K42

K84-ub

SSDANERkGGILAIA

mTOR (human)	SSDANERkGGILAIA	K84-ub
mTOR (mouse)	SSDANERKGGILAIA	K84
mTOR (rat)	SSDANERKGGILAIA	K84

S92-p

GGILAIAsLIGVEGG

mTOR (human)	GGILAIAsLIGVEGG	S92-p
mTOR (mouse)	GGILAIASLIGVEGG	S92
mTOR (rat)	GGILAIASLIGVEGG	S92

T102-p

GVEGGNAtRIGRFAN

mTOR (human)	GVEGGNAtRIGRFAN	T102-p
mTOR (mouse)	GVEGGNSTRIGRFAN	T102
mTOR (rat)	GVEGGNSTRIGRFAN	T102

Y110-p

RIGRFANyLRNLLPS

mTOR (human)	RIGRFANyLRNLLPS	Y110-p
mTOR (mouse)	RIGRFANYLRNLLPS	Y110
mTOR (rat)	RIGRFANYLRNLLPS	Y110

K128-ub

VVMEMASkAIGRLAM

mTOR (human)	VVMEMASkAIGRLAM	K128-ub
mTOR (mouse)	VVMEMASKAIGRLAM	K128
mTOR (rat)	VVMEMASKAIGRLAM	K128

K230-ub

REPKEMQkPQWYRHT

mTOR (human)	REPKEMQkPQWYRHT	K230-ub
mTOR (mouse)	REPKEMQkPQWYRHT	K230-ub
mTOR (rat)	REPKEMQKPQWYRHT	K230

K230

REPKEMQKPQWYRHT

mTOR (human)	REPKEMQKPQWYRHT	K230
mTOR (mouse)	REPKEMQKPQWYRHT	K230
mTOR (rat)	REPKEMQkPQWYRHT	K230-ac

K243-ub

HTFEEAEkGFDETLA

mTOR (human)	HTFEEAEkGFDETLA	K243-ub
mTOR (mouse)	HTFEEAEkGFDETLA	K243-ub
mTOR (rat)	HTFEEAEKGFDETLA	K243

K251-ub

GFDETLAkEKGMNRD

mTOR (human)	GFDETLAkEKGMNRD	K251-ub
mTOR (mouse)	GFDETLAKEKGMNRD	K251
mTOR (rat)	GFDETLAKEKGMNRD	K251

K298-ub

QQQLVHDkYCkDLMG

mTOR (human)	QQQLVHDkYCkDLMG	K298-ub
mTOR (mouse)	QQQLVHDkYCKDLMG	K298-ub
mTOR (rat)	QQQLVHDKYCKDLMG	K298

K301-ub

LVHDkYCkDLMGFGt

mTOR (human)	LVHDkYCkDLMGFGt	K301-ub
mTOR (mouse)	LVHDkYCKDLMGFGT	K301
mTOR (rat)	LVHDKYCKDLMGFGT	K301

T308-p

kDLMGFGtkPRHItP

mTOR (human)	kDLMGFGtkPRHItP	T308-p
mTOR (mouse)	KDLMGFGTKPRHITP	T308
mTOR (rat)	KDLMGFGTKPRHITP	T308

K309-ub

DLMGFGtkPRHItPF

mTOR (human)	DLMGFGtkPRHItPF	K309-ub
mTOR (mouse)	DLMGFGTKPRHITPF	K309
mTOR (rat)	DLMGFGTKPRHITPF	K309

T314-p

GtkPRHItPFTSFQA

mTOR (human)	GtkPRHItPFTSFQA	T314-p
mTOR (mouse)	GTKPRHITPFTSFQA	T314
mTOR (rat)	GTKPRHITPFTSFQA	T314

K369-ub

CRDLMEEkFDQVCQW

mTOR (human)	CRDLMEEkFDQVCQW	K369-ub
mTOR (mouse)	CRDLMEEKFDQVCQW	K369
mTOR (rat)	CRDLMEEKFDQVCQW	K369

K379-ub

QVCQWVLkCRNSkNS

mTOR (human)	QVCQWVLkCRNSkNS	K379-ub
mTOR (mouse)	QVCQWVLKCRSSKNS	K379
mTOR (rat)	QVCQWVLKCRSSKNS	K379

K384-ub

VLkCRNSkNSLIQMT

mTOR (human)	VLkCRNSkNSLIQMT	K384-ub
mTOR (mouse)	VLKCRSSKNSLIQMT	K384
mTOR (rat)	VLKCRSSKNSLIQMT	K384

K449-ub

VAVRSEFkVYLPRVL

mTOR (human)	VAVRSEFkVYLPRVL	K449-ub
mTOR (mouse)	VAVRSEFKVYLPRVL	K449
mTOR (rat)	VAVRSEFKVYLPRVL	K449

K533-ub

RQIPQLKkDIQDGLL

mTOR (human)	RQIPQLKkDIQDGLL	K533-ub
mTOR (mouse)	RQIPQLKKDIQDGLL	K533
mTOR (rat)	RQIPQLKKDIQDGLL	K533

S567-p

GLAHQLAsPGLTTLP

Upstream

Treatment

nocodazole

mTOR (human)	GLAHQLAsPGLTTLP	S567-p
mTOR (mouse)	GLAHQLASPGLTTLP	S567
mTOR (rat)	GLAHQLASPGLTTLP	S567

K616-ub

HFLNSEHkEIRMEAA

mTOR (human)	HFLNSEHkEIRMEAA	K616-ub
mTOR (mouse)	HFLNSEHKEIRMEAA	K616
mTOR (rat)	HFLNSEHKEIRMEAA	K616

T631-p

RTCSRLLtPSIHLIS

Upstream

Downstream

Effects on Modified Protein

protein degradation
ubiquitination

Regulatory protein:

DYRK2 (human)

mTOR (human)	RTCSRLLtPSIHLIS	T631-p
mTOR (mouse)	RTCSRLLTPSIHLIS	T631
mTOR (rat)	RTCSRLLTPSIHLIS	T631

T665-p

KLLVVGItDPDPDIR

mTOR (human)	KLLVVGItDPDPDIR	T665-p
mTOR (mouse)	KLLVVGITDPDPDIR	T665
mTOR (rat)	KLLVVGITDPDPDIR	T665

S719-p

ICTVGRLsSMNPAFV

mTOR (human)	ICTVGRLsSMNPAFV	S719-p
mTOR (mouse)	ICTVGRLSSMNPAFV	S719
mTOR (rat)	ICTVGRLSSMNPAFV	S719

K777-ub

PYMEPILkALILKLK

mTOR (human)	PYMEPILkALILKLK	K777-ub
mTOR (mouse)	PYMEPILKALILKLK	K777
mTOR (rat)	PYMEPILKALILKLK	K777

Y858

TGYVVEPYRKyPTLL

mTOR (human)	TGYVVEPYRKyPTLL	Y858
mTOR (mouse)	TGYVVEPyRKyPTLL	Y858-p
mTOR (rat)	TGYVVEPYRKYPTLL	Y858

Y861-p

VVEPYRKyPTLLEVL

mTOR (human)	VVEPYRKyPTLLEVL	Y861-p
mTOR (mouse)	VVEPyRKyPTLLEVL	Y861-p
mTOR (rat)	VVEPYRKYPTLLEVL	Y861

T880-p

KTEQNQGtRREAIRV

mTOR (human)	KTEQNQGtRREAIRV	T880-p
mTOR (mouse)	KTEQNQGtRREAIRV	T880-p
mTOR (rat)	KTEQNQGTRREAIRV	T880

K898-ub

LGALDPYkHkVNIGM

mTOR (human)	LGALDPYkHkVNIGM	K898-ub
mTOR (mouse)	LGALDPYkHkVNIGM	K898-ub
mTOR (rat)	LGALDPYKHKVNIGM	K898

K900-ub

ALDPYkHkVNIGMID

mTOR (human)	ALDPYkHkVNIGMID	K900-ub
mTOR (mouse)	ALDPYkHkVNIGMID	K900-ub
mTOR (rat)	ALDPYKHKVNIGMID	K900

S909-p

NIGMIDQsRDASAVs

mTOR (human)	NIGMIDQsRDASAVs	S909-p
mTOR (mouse)	NIGMIDQSRDASAVS	S909
mTOR (rat)	NIGMIDQSRDASAVS	S909

S916-p

sRDASAVsLsESKSS

mTOR (human)	sRDASAVsLsESKSS	S916-p
mTOR (mouse)	SRDASAVSLSESKSS	S916
mTOR (rat)	SRDASAVSLSESKSS	S916

S918-p

DASAVsLsESKSSQD

mTOR (human)	DASAVsLsESKSSQD	S918-p
mTOR (mouse)	DASAVSLSESKSSQD	S918
mTOR (rat)	DASAVSLSESKSSQD	S918

S1131-p

APEAPLPsRkAALET

mTOR (human)	APEAPLPsRkAALET	S1131-p
mTOR (mouse)	APEVPLPSRKAALET	S1131
mTOR (rat)	APEVPLPSRKAALET	S1131

K1133-ub

EAPLPsRkAALETVD

mTOR (human)	EAPLPsRkAALETVD	K1133-ub
mTOR (mouse)	EVPLPSRKAALETVD	K1133
mTOR (rat)	EVPLPSRKAALETVD	K1133

T1162-p

IIHPIVRtLDQsPEL

Upstream

Treatment

EGF
MG132_withdrawal
nocodazole
SB202190
U0126

mTOR (human)	IIHPIVRtLDQsPEL	T1162-p
mTOR (mouse)	IIHPIVRtLDQSPEL	T1162-p
mTOR (rat)	IIHPIVRTLDQSPEL	T1162

S1166-p

IVRtLDQsPELRstA

Upstream

Treatment

EGF
nocodazole
SB202190

mTOR (human)	IVRtLDQsPELRstA	S1166-p
mTOR (mouse)	IVRtLDQSPELRSTA	S1166
mTOR (rat)	IVRTLDQSPELRSTA	S1166

S1171-p

DQsPELRstAMDTLS

mTOR (human)	DQsPELRstAMDTLS	S1171-p
mTOR (mouse)	DQSPELRSTAMDTLS	S1171
mTOR (rat)	DQSPELRSTAMDTLS	S1171

T1172-p

QsPELRstAMDTLSS

mTOR (human)	QsPELRstAMDTLSS	T1172-p
mTOR (mouse)	QSPELRSTAMDTLSS	T1172
mTOR (rat)	QSPELRSTAMDTLSS	T1172

K1187-ub

LVFQLGKkyQIFIPM

mTOR (human)	LVFQLGKkyQIFIPM	K1187-ub
mTOR (mouse)	LVFQLGKKYQIFIPM	K1187
mTOR (rat)	LVFQLGKKYQIFIPM	K1187

Y1188-p

VFQLGKkyQIFIPMV

mTOR (human)	VFQLGKkyQIFIPMV	Y1188-p
mTOR (mouse)	VFQLGKKYQIFIPMV	Y1188
mTOR (rat)	VFQLGKKYQIFIPMV	Y1188

K1197-ub

IFIPMVNkVLVRHRI

mTOR (human)	IFIPMVNkVLVRHRI	K1197-ub
mTOR (mouse)	IFIPMVNKVLVRHRI	K1197
mTOR (rat)	IFIPMVNKVLVRHRI	K1197

K1218-ac

VLICRIVkGYTLADE

mTOR (human)	VLICRIVkGYTLADE	K1218-ac
mTOR (mouse)	VLICRIVKGYTLADE	K1218
mTOR (rat)	VLICRIVkGYTLADE	K1218-ac

K1218-ub

VLICRIVkGYTLADE

mTOR (human)	VLICRIVkGYTLADE	K1218-ub
mTOR (mouse)	VLICRIVkGYTLADE	K1218-ub
mTOR (rat)	VLICRIVKGYTLADE	K1218

Y1232-p

EEEDPLIyQHRMLRS

mTOR (human)	EEEDPLIyQHRMLRS	Y1232-p
mTOR (mouse)	EEEDPLIYQHRMLRS	Y1232
mTOR (rat)	EEEDPLIYQHRMLRS	Y1232

K1256-ac

PVETGPMkkLHVstI

mTOR (human)	PVETGPMkkLHVstI	K1256-ac
mTOR (mouse)	PVETGPMKkLHVstI	K1256
mTOR (rat)	PVETGPMKKLHVsTI	K1256

K1256-ub

PVETGPMkkLHVstI

mTOR (human)	PVETGPMkkLHVstI	K1256-ub
mTOR (mouse)	PVETGPMkkLHVstI	K1256-ub
mTOR (rat)	PVETGPMKKLHVsTI	K1256

K1257-ub

VETGPMkkLHVstIN

mTOR (human)	VETGPMkkLHVstIN	K1257-ub
mTOR (mouse)	VETGPMkkLHVstIN	K1257-ub
mTOR (rat)	VETGPMKKLHVsTIN	K1257

S1261-p

PMkkLHVstINLQkA

Upstream

Downstream

Effects on Modified Protein

phosphorylation

Effects on Biological Processes:

cell growth, induced
signaling pathway regulation

Treatment

amino_acid_starvation
amino_acids
insulin
ischemia
MLN8054
rapamycin
wortmannin

mTOR (human)	PMkkLHVstINLQkA	S1261-p
mTOR (mouse)	PMkkLHVstINLQKA	S1261-p
mTOR (rat)	PMKKLHVsTINLQKA	S1261-p

T1262-p

MkkLHVstINLQkAW

mTOR (human)	MkkLHVstINLQkAW	T1262-p
mTOR (mouse)	MkkLHVstINLQKAW	T1262-p
mTOR (rat)	MKKLHVsTINLQKAW	T1262

K1267-ub

VstINLQkAWGAARR

mTOR (human)	VstINLQkAWGAARR	K1267-ub
mTOR (mouse)	VstINLQKAWGAARR	K1267
mTOR (rat)	VsTINLQKAWGAARR	K1267

S1288-p

LEWLRRLsLELLkDS

mTOR (human)	LEWLRRLsLELLkDS	S1288-p
mTOR (mouse)	LEWLRRLSLELLkDS	S1288
mTOR (rat)	LEWLRRLSLELLKDS	S1288

K1293-ub

RLsLELLkDSSsPsL

mTOR (human)	RLsLELLkDSSsPsL	K1293-ub
mTOR (mouse)	RLSLELLkDSSSPSL	K1293-ub
mTOR (rat)	RLSLELLKDSSSPSL	K1293

S1297-p

ELLkDSSsPsLRSCW

mTOR (human)	ELLkDSSsPsLRSCW	S1297-p
mTOR (mouse)	ELLkDSSSPSLRSCW	S1297
mTOR (rat)	ELLKDSSSPSLRSCW	S1297

S1299-p

LkDSSsPsLRSCWAL

mTOR (human)	LkDSSsPsLRSCWAL	S1299-p
mTOR (mouse)	LkDSSSPSLRSCWAL	S1299
mTOR (rat)	LKDSSSPSLRSCWAL	S1299

K1395-ub

AKCRAYAkALHYkEL

mTOR (human)	AKCRAYAkALHYkEL	K1395-ub
mTOR (mouse)	AKCRAYAKALHYkEL	K1395
mTOR (rat)	AKCRAYAKALHYKEL	K1395

K1400-ub

YAkALHYkELEFQkG

mTOR (human)	YAkALHYkELEFQkG	K1400-ub
mTOR (mouse)	YAKALHYkELEFQkG	K1400-ub
mTOR (rat)	YAKALHYKELEFQKG	K1400

K1406-ub

YkELEFQkGPTPAIL

mTOR (human)	YkELEFQkGPTPAIL	K1406-ub
mTOR (mouse)	YkELEFQkGPTPAIL	K1406-ub
mTOR (rat)	YKELEFQKGPTPAIL	K1406

S1415-p

PTPAILEsLIsINNK

Upstream

Downstream

Effects on Modified Protein

enzymatic activity, induced
molecular association, regulation
phosphorylation

Effects on Biological Processes:

carcinogenesis, induced
cell growth, induced

Kinase, in vitro:

IKKA (human)

Putative in vivo kinases:

IKKA (human)

Regulatory protein:

Akt1 (human)
Akt2 (human)
PTEN (human)

Treatment

insulin
siRNA

mTOR (human)	PTPAILEsLIsINNK	S1415-p
mTOR (mouse)	PTPAILESLIsINNK	S1415
mTOR (rat)	PTPAILESLISINNK	S1415

S1418-p

AILEsLIsINNKLQQ

Upstream

Kinase, in vitro:

IKKA (human)

mTOR (human)	AILEsLIsINNKLQQ	S1418-p
mTOR (mouse)	AILESLIsINNKLQQ	S1418-p
mTOR (rat)	AILESLISINNKLQQ	S1418

K1465-ub

DALVAYDkKMDTNkD

mTOR (human)	DALVAYDkKMDTNkD	K1465-ub
mTOR (mouse)	DALVAYDkKMDTNkE	K1465-ub
mTOR (rat)	DALVAYDKKMDTNKD	K1465

K1471-ub

DkKMDTNkDDPELML

mTOR (human)	DkKMDTNkDDPELML	K1471-ub
mTOR (mouse)	DkKMDTNkEDPELML	K1471-ub
mTOR (rat)	DKKMDTNKDDPELML	K1471

K1500-ub

LHQQCCEkWtLVNDE

mTOR (human)	LHQQCCEkWtLVNDE	K1500-ub
mTOR (mouse)	LHQQCCEKWTLVNDE	K1500
mTOR (rat)	LHQQCCEKWTLVNDE	K1500

T1502-p

QQCCEkWtLVNDETQ

mTOR (human)	QQCCEkWtLVNDETQ	T1502-p
mTOR (mouse)	QQCCEKWTLVNDETQ	T1502
mTOR (rat)	QQCCEKWTLVNDETQ	T1502

K1511-ub

VNDETQAkMARMAAA

mTOR (human)	VNDETQAkMARMAAA	K1511-ub
mTOR (mouse)	VNDETQAkMARMAAA	K1511-ub
mTOR (rat)	VNDETQAKMARMAAA	K1511

K1566-ub

LAQQCIDkARDLLDA

mTOR (human)	LAQQCIDkARDLLDA	K1566-ub
mTOR (mouse)	LAQQCIDKARDLLDA	K1566
mTOR (rat)	LAQQCIDKARDLLDA	K1566

K1635-ub

RIVEDWQkILMVRSL

mTOR (human)	RIVEDWQkILMVRSL	K1635-ub
mTOR (mouse)	RIVEDWQKILMVRSL	K1635
mTOR (rat)	RIVEDWQKILMVRSL	K1635

K1655-ub

EDMRTWLkYASLCGk

mTOR (human)	EDMRTWLkYASLCGk	K1655-ub
mTOR (mouse)	EDMRTWLkYASLCGK	K1655-ub
mTOR (rat)	EDMRTWLKyASLCGK	K1655

Y1656

DMRTWLkYASLCGkS

mTOR (human)	DMRTWLkYASLCGkS	Y1656
mTOR (mouse)	DMRTWLkYASLCGKS	Y1656
mTOR (rat)	DMRTWLKyASLCGKS	Y1656-p

K1662-ub

kYASLCGkSGRLALA

mTOR (human)	kYASLCGkSGRLALA	K1662-ub
mTOR (mouse)	kYASLCGKSGRLALA	K1662
mTOR (rat)	KyASLCGKSGRLALA	K1662

K1745-ub

QHKQELHkLMARCFL

mTOR (human)	QHKQELHkLMARCFL	K1745-ub
mTOR (mouse)	QHKQELHKLMARCFL	K1745
mTOR (rat)	QHKQELHKLMARCFL	K1745

Y1804-p

NFEAVLHyKHQNQAR

mTOR (human)	NFEAVLHyKHQNQAR	Y1804-p
mTOR (mouse)	NFEAVLHYKHQNQAR	Y1804
mTOR (rat)	NFEAVLHYKHQNQAR	Y1804

S1821-p

KKKLRHAsGANITNA

mTOR (human)	KKKLRHAsGANITNA	S1821-p
mTOR (mouse)	KKKLRHASGANITNA	S1821
mTOR (rat)	KKKLRHASGANITNA	S1821

S1859-p

EAESTENsPTPSPLQ

mTOR (human)	EAESTENsPTPSPLQ	S1859-p
mTOR (mouse)	EAESNENSPTPSPLQ	S1859
mTOR (rat)	EAESNESSPTPSPLQ	S1859

T1870-p

SPLQKKVtEDLsKtL

mTOR (human)	SPLQKKVtEDLsKtL	T1870-p
mTOR (mouse)	SPLQKKVTEDLSKTL	T1870
mTOR (rat)	SPLQKKVTEDLSKTL	T1870

S1874-p

KKVtEDLsKtLLMyT

mTOR (human)	KKVtEDLsKtLLMyT	S1874-p
mTOR (mouse)	KKVTEDLSKTLLLYT	S1874
mTOR (rat)	KKVTEDLSKTLLLYT	S1874

T1876-p

VtEDLsKtLLMyTVP

mTOR (human)	VtEDLsKtLLMyTVP	T1876-p
mTOR (mouse)	VTEDLSKTLLLYTVP	T1876
mTOR (rat)	VTEDLSKTLLLYTVP	T1876

Y1880-p

LsKtLLMyTVPAVQG

mTOR (human)	LsKtLLMyTVPAVQG	Y1880-p
mTOR (mouse)	LSKTLLLYTVPAVQG	Y1880
mTOR (rat)	LSKTLLLYTVPAVQG	Y1880

S1893-p

QGFFRSIsLSRGNNL

Upstream

Treatment

ischemia

mTOR (human)	QGFFRSIsLSRGNNL	S1893-p
mTOR (mouse)	QGFFRSISLSRGNNL	S1893
mTOR (rat)	QGFFRSISLSRGNNL	S1893

T1948-p

QLIARIDtPRPLVGR

mTOR (human)	QLIARIDtPRPLVGR	T1948-p
mTOR (mouse)	QLIARIDTPRPLVGR	T1948
mTOR (rat)	QLIARIDTPRPLVGR	T1948

K1993-ub

ARHNAANkILKNMCE

mTOR (human)	ARHNAANkILKNMCE	K1993-ub
mTOR (mouse)	ARHNAANKILKNMCE	K1993
mTOR (rat)	ARHNAANKILKNMCE	K1993

K2045-ub

YFGERNVkGMFEVLE

mTOR (human)	YFGERNVkGMFEVLE	K2045-ub
mTOR (mouse)	YFGERNVKGMFEVLE	K2045
mTOR (rat)	YFGERNVKGMFEVLE	K2045

K2066-ub

ERGPQTLkETsFNQA

mTOR (human)	ERGPQTLkETsFNQA	K2066-ub
mTOR (mouse)	ERGPQTLkETsFNQA	K2066-ub
mTOR (rat)	ERGPQTLKETSFNQA	K2066

S2069-p

PQTLkETsFNQAYGR

mTOR (human)	PQTLkETsFNQAYGR	S2069-p
mTOR (mouse)	PQTLkETsFNQAYGR	S2069-p
mTOR (rat)	PQTLKETSFNQAYGR	S2069

S2155-p

QPIIRIQsIAPsLQV

mTOR (human)	QPIIRIQsIAPsLQV	S2155-p
mTOR (mouse)	QPIIRIQSIAPSLQV	S2155
mTOR (rat)	QPIIRIQSIAPSLQV	S2155

S2159-p

RIQsIAPsLQVItSk

Upstream

Downstream

Effects on Modified Protein

molecular association, regulation
phosphorylation

Effects on Biological Processes:

cell cycle regulation
cell growth, induced
signaling pathway regulation

Treatment

staurosporine
Torin1

mTOR (human)	RIQsIAPsLQVItSk	S2159-p
mTOR (mouse)	RIQSIAPSLQVITSK	S2159
mTOR (rat)	RIQSIAPSLQVITSK	S2159

T2164-p

APsLQVItSkQRPRK

Upstream

Downstream

Effects on Modified Protein

molecular association, regulation
phosphorylation

Effects on Biological Processes:

cell cycle regulation
cell growth, induced
signaling pathway regulation

Treatment

staurosporine
Torin1

mTOR (human)	APsLQVItSkQRPRK	T2164-p
mTOR (mouse)	APSLQVITSKQRPRK	T2164
mTOR (rat)	APSLQVITSKQRPRK	T2164

K2166-ub

sLQVItSkQRPRKLT

mTOR (human)	sLQVItSkQRPRKLT	K2166-ub
mTOR (mouse)	SLQVITSKQRPRKLT	K2166
mTOR (rat)	SLQVITSKQRPRKLT	K2166

K2218-ub

NDPTSLRkNLSIQRY

mTOR (human)	NDPTSLRkNLSIQRY	K2218-ub
mTOR (mouse)	NDPTSLRKNLSIQRY	K2218
mTOR (rat)	NDPTSLRKNLSIQRY	K2218

K2301-ub

TAGDDLAkLLWLKSP

mTOR (human)	TAGDDLAkLLWLKSP	K2301-ub
mTOR (mouse)	TAGDDLAKLLWLKSP	K2301
mTOR (rat)	TAGDDLAKLLWLKSP	K2301

K2370-ub

EVAMTREkFPEKIPF

mTOR (human)	EVAMTREkFPEKIPF	K2370-ub
mTOR (mouse)	EVAMTREkFPEKIPF	K2370-ub
mTOR (rat)	EVAMTREKFPEKIPF	K2370

T2380-p

EKIPFRLtRMLTNAM

mTOR (human)	EKIPFRLtRMLTNAM	T2380-p
mTOR (mouse)	EKIPFRLTRMLTNAM	T2380
mTOR (rat)	EKIPFRLTRMLTNAM	T2380

T2434-p

LNWRLMDtNtKGNKR

mTOR (human)	LNWRLMDtNtKGNKR	T2434-p
mTOR (mouse)	LNWRLMDTNTKGNKR	T2434
mTOR (rat)	LNWRLMDTNAKGNKR	T2434

T2436-p

WRLMDtNtKGNKRsR

mTOR (human)	WRLMDtNtKGNKRsR	T2436-p
mTOR (mouse)	WRLMDTNTKGNKRsR	T2436
mTOR (rat)	WRLMDTNAKGNKRSR	A2436

S2442-p

NtKGNKRsRtRtDsy

mTOR (human)	NtKGNKRsRtRtDsy	S2442-p
mTOR (mouse)	NTKGNKRsRtRtDsy	S2442-p
mTOR (rat)	NAKGNKRSRTRTDsY	S2442

T2444-p

KGNKRsRtRtDsysA

Upstream

Treatment

gefitinib

mTOR (human)	KGNKRsRtRtDsysA	T2444-p
mTOR (mouse)	KGNKRsRtRtDsysA	T2444-p
mTOR (rat)	KGNKRSRTRTDsYSA	T2444

T2446-p

NKRsRtRtDsysAGQ

Upstream

Kinase, in vitro:

Akt1 (human)
p70S6K (human)

Putative in vivo kinases:

p70S6K (human)

Treatment

gefitinib
insulin
phorbol_ester
rapamycin
wortmannin

mTOR (human)	NKRsRtRtDsysAGQ	T2446-p
mTOR (mouse)	NKRsRtRtDsysAGQ	T2446-p
mTOR (rat)	NKRSRTRTDsYSAGQ	T2446

S2448-p

RsRtRtDsysAGQsV

Upstream

Downstream

128

122

mTOR (human)
S2448-p

mTOR (mouse)
S2448-p

mTOR (rat)
S2448-p

Effects on Modified Protein

enzymatic activity, induced
intracellular localization
phosphorylation

Effects on Biological Processes:

autophagy, inhibited
carcinogenesis, induced
cell growth, induced
signaling pathway regulation

Kinase, in vitro:

Akt1 (human)
p70S6K (human)

Putative in vivo kinases:

Akt1 (human)
p70S6K (human)

Regulatory protein:

Akt1 (cow)
Akt1 (human)
AMPKA1 (human)
CIP2A (human)
DUSP6 (human)
FAK (human)
GRP78 (human)
IL24 (human)
mTOR (human)
Notch 1 (human)
NuaK1 (human)
p53 (human)
PDCD6 (human)
PHLPP (human)
PHLPP2 (human)
RAF1 (human)
Raptor (human)
RICTOR (human)

Treatment

acadesine
afatinib
Akt-I-1
aloe-emodin
amino_acid_starvation
amino_acids
anti-HLA
As2O3
AZD8055
bicyclol
Cbz-B3A
colforsin
collagen XIX (NC1 domain)
compound_C
cycloheximide
DMSO
exercise
fasting
GDNF
gefitinib
GSK2334470
heregulin
HGF
IFN-beta
IFN-gamma
IGF-1
IL-24
IL-3
imatinib
insulin
JQ1
L-glutamine_withdrawal
laminar flow
liothyronine
LLL12
LPS
LY294002
metformin
methyl-beta-cyclodextrin
MHY1485
nocodazole
oscillatory_flow
OSI-027
osteopontin
OSU-03012
ouabain
pemetrexed
phorbol_ester
pimenta doica
PP2
PP242
pravastatin
QLT0267
RAD001
rapamycin
resveratrol
retinoic_acid
RGD
SB202190
SB203580
SB216763
selenite
serum
sildenafil
siRNA
sorafenib
Su11274
SU6656
sunitinib
triptolide
tunicamycin
U0126
UV
VEGF
virus infection
wortmannin

mTOR (human)	RsRtRtDsysAGQsV	S2448-p
mTOR (mouse)	RsRtRtDsysAGQsV	S2448-p
mTOR (rat)	RSRTRTDsYSAGQSV	S2448-p

Y2449-p

sRtRtDsysAGQsVE

Upstream

Treatment

gefitinib
Su11274

mTOR (human)	sRtRtDsysAGQsVE	Y2449-p
mTOR (mouse)	sRtRtDsysAGQsVE	Y2449-p
mTOR (rat)	SRTRTDsYSAGQSVE	Y2449

S2450-p

RtRtDsysAGQsVEI

Upstream

Treatment

gefitinib
imatinib

mTOR (human)	RtRtDsysAGQsVEI	S2450-p
mTOR (mouse)	RtRtDsysAGQsVEI	S2450-p
mTOR (rat)	RTRTDsYSAGQSVEI	S2450

S2454-p

DsysAGQsVEILDGV

Upstream

Kinase, in vitro:

mTOR (human)

Treatment

gefitinib
imatinib
Su11274

mTOR (human)	DsysAGQsVEILDGV	S2454-p
mTOR (mouse)	DsysAGQsVEILDGV	S2454-p
mTOR (rat)	DsYSAGQSVEILDGV	S2454

T2471-p

GEPAHKKtGttVPEs

mTOR (human)	GEPAHKKtGttVPEs	T2471-p
mTOR (mouse)	GEPAHKKAGttVPEs	A2471
mTOR (rat)	GEPAHKKTGTTVPEs	T2471

T2473-p

PAHKKtGttVPEsIH

Upstream

Kinase, in vitro:

mTOR (human)

mTOR (human)	PAHKKtGttVPEsIH	T2473-p
mTOR (mouse)	PAHKKAGttVPEsIH	T2473-p
mTOR (rat)	PAHKKTGTTVPEsIH	T2473

T2474-p

AHKKtGttVPEsIHs

Upstream

Kinase, in vitro:

mTOR (human)

mTOR (human)	AHKKtGttVPEsIHs	T2474-p
mTOR (mouse)	AHKKAGttVPEsIHs	T2474-p
mTOR (rat)	AHKKTGTTVPEsIHs	T2474

S2478-p

tGttVPEsIHsFIGD

Upstream

Kinase, in vitro:

mTOR (human)

mTOR (human)	tGttVPEsIHsFIGD	S2478-p
mTOR (mouse)	AGttVPEsIHsFIGD	S2478-p
mTOR (rat)	TGTTVPEsIHsFIGD	S2478-p

S2481-p

tVPEsIHsFIGDGLV

Upstream

Downstream

mTOR (human)
S2481-p

2974 : Phospho-mTOR (Ser2481) Antibody

mTOR (mouse)
S2481-p

2974 : Phospho-mTOR (Ser2481) Antibody

mTOR (rat)
S2481-p

2974 : Phospho-mTOR (Ser2481) Antibody

Effects on Modified Protein

enzymatic activity, induced

Effects on Biological Processes:

cell cycle regulation

Kinase, in vitro:

mTOR (human)

Putative in vivo kinases:

mTOR (human)

Regulatory protein:

DYRK2 (human)
HRas (human)
ILK (human)
mTOR (human)
Notch 1 (human)
p53 (human)
PIK3C2A (human)
PIK3CB (human)
PIP3-E (human)
Raptor (human)
RHEB (human)
RICTOR (human)
Sin1 (human)
TBK1 (human)
ULK1 (human)

Treatment

2-deoxyglucose
5-HT
amino_acid_starvation
amino_acids
angiotensin_2
anisomycin
AZD8055
calyculin_A
Cbz-B3A
celastrol
collagen XIX (NC1 domain)
EGF
GSK2334470
histidinol
IFN-gamma
IGF-1
IL-6
imatinib
insulin
ionizing_radiation
KU-0063794
LPS
LY294002
ML120B
OSI-027
pemetrexed
phorbol_ester
PP242
rapamycin
selenite
serum
serum_withdrawal
sildenafil
siRNA
SP600125
staurosporine
sunitinib
Torin1
wortmannin

mTOR (human)	tVPEsIHsFIGDGLV	S2481-p
mTOR (mouse)	tVPEsIHsFIGDGLV	S2481-p
mTOR (rat)	TVPEsIHsFIGDGLV	S2481-p

K2489-ub

FIGDGLVkPEALNKk

mTOR (human)	FIGDGLVkPEALNKk	K2489-ub
mTOR (mouse)	FIGDGLVKPEALNKk	K2489
mTOR (rat)	FIGDGLVKPEALNKK	K2489

K2496-ub

kPEALNKkAIQIINR

mTOR (human)	kPEALNKkAIQIINR	K2496-ub
mTOR (mouse)	KPEALNKkAIQIINR	K2496-ub
mTOR (rat)	KPEALNKKAIQIINR	K2496