Other Species / Isoforms
  Syk (rat)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
Y14
DNANHLTYFFGNITR
1 1
Syk (human) DSANHLPFFFGNITR F15
Syk iso2 (human) DSANHLPFFFGNITR F15
Syk (mouse) DSANHLTyFFGNITR Y14-p
Syk (rat) DNANHLTYFFGNITR Y14
Y27
TREEAEDYLVQGGMT
1 4
Syk (human) TREEAEDyLVQGGMS Y28-p
Syk iso2 (human) TREEAEDYLVQGGMS Y28
Syk (mouse) TREEAEDyLVQGGMT Y27-p
Syk (rat) TREEAEDYLVQGGMT Y27
Y46
LLRQSRNYLGGFALS
1 3
Syk (human) LLRQSRNyLGGFALS Y47-p
Syk iso2 (human) LLRQSRNYLGGFALS Y47
Syk (mouse) LLRQSRNyLGGFALS Y46-p
Syk (rat) LLRQSRNYLGGFALS Y46
K59
LSVAHNRKAHHYTIE
0 3
Syk (human) LSVAHGRkAHHYTIE K60-ub
Syk iso2 (human) LSVAHGRKAHHYTIE K60
Syk (mouse) LSVAHNRKAHHyTIE K59
Syk (rat) LSVAHNRKAHHYTIE K59
Y63
HNRKAHHYTIERELN
1 1
Syk (human) HGRkAHHYTIERELN Y64
Syk iso2 (human) HGRKAHHYTIERELN Y64
Syk (mouse) HNRKAHHyTIERELN Y63-p
Syk (rat) HNRKAHHYTIERELN Y63
T72
IERELNGTYAISGGR
0 1
Syk (human) IERELNGtyAIAGGR T73-p
Syk iso2 (human) IERELNGTYAIAGGR T73
Syk (mouse) IERELNGTyAISGGR T72
Syk (rat) IERELNGTYAISGGR T72
Y73
ERELNGTYAISGGRA
1 54
Syk (human) ERELNGtyAIAGGRT Y74-p
Syk iso2 (human) ERELNGTYAIAGGRT Y74
Syk (mouse) ERELNGTyAISGGRA Y73-p
Syk (rat) ERELNGTYAISGGRA Y73
Y90
SPADLCHYHSQEPEG
1 3
Syk (human) SPADLCHyHSQESDG Y91-p
Syk iso2 (human) SPADLCHYHSQESDG Y91
Syk (mouse) SPADLCHyHSQEPDG Y90-p
Syk (rat) SPADLCHYHSQEPEG Y90
K104
GLVCLLKKPFNRPPG
0 1
Syk (human) GLVCLLKkPFNRPQG K105-ac
Syk iso2 (human) GLVCLLKKPFNRPQG K105
Syk (mouse) GLICLLKKPFNRPPG K104
Syk (rat) GLVCLLKKPFNRPPG K104
K115
RPPGVQPKTGPFEDL
0 1
Syk (human) RPQGVQPkTGPFEDL K116-ac
Syk iso2 (human) RPQGVQPKTGPFEDL K116
Syk (mouse) RPPGVQPKTGPFEDL K115
Syk (rat) RPPGVQPKTGPFEDL K115
Y130-p
KENLIREyVKQTWNL
9 3
Syk (human) KENLIREYVKQTWNL Y131
Syk iso2 (human) KENLIREYVKQTWNL Y131
Syk (mouse) KENLIREyVKQTWNL Y130-p
Syk (rat) KENLIREyVKQTWNL Y130-p
T160
LEKLIATTAHEKMPW
0 1
Syk (human) LEKLIATtAHEKMPW T161-p
Syk iso2 (human) LEKLIATTAHEKMPW T161
Syk (mouse) LEKLIATTAHEKMPW T160
Syk (rat) LEKLIATTAHEKMPW T160
S177
GNISRDESEQTVLIG
1 0
Syk (human) GKISREEsEQIVLIG S178-p
Syk iso2 (human) GKISREESEQIVLIG S178
Syk (mouse) GNISRDESEQTVLIG S177
Syk (rat) GNISRDESEQTVLIG S177
S201
RARDNNGSFALCLLH
0 2
Syk (human) RARDNNGsyALCLLH S202-p
Syk iso2 (human) RARDNNGSYALCLLH S202
Syk (mouse) RARDNSGsyALCLLH S201-p
Syk (rat) RARDNNGSFALCLLH S201
F202
ARDNNGSFALCLLHE
1 32
Syk (human) ARDNNGsyALCLLHE Y203-p
Syk iso2 (human) ARDNNGSYALCLLHE Y203
Syk (mouse) ARDNSGsyALCLLHE Y202-p
Syk (rat) ARDNNGSFALCLLHE F202
Y243
LWQLVEHYSYKPDGL
1 3
Syk (human) LWQLVEHySYKADGL Y244-p
Syk iso2 (human) LWQLVEHYSYKADGL Y244
Syk (mouse) LWQLVEHySYKPDGL Y243-p
Syk (rat) LWQLVEHYSYKPDGL Y243
T255
DGLLRVLTVPCQKIG
0 1
Syk (human) DGLLRVLtVPCQKIG T256-p
Syk iso2 (human) DGLLRVLTVPCQKIG T256
Syk (mouse) DGLLRVLTVPCQKIG T255
Syk (rat) DGLLRVLTVPCQKIG T255
S270
VQMGHPGSSNAHPVT
1 9
Syk (human) NFGGRPQLPGSHPAT L276
Syk iso2 (human) NFGGRPQLPGSHPAS L276
Syk (mouse) AQMGHPGsPNAHPVT S270-p
Syk (rat) VQMGHPGSSNAHPVT S270
S279
NAHPVTWSPGGIISR
1 3
Syk (human) GSHPATWSAGGIISR S285
Syk iso2 (human) gap -
Syk (mouse) NAHPVTWsPGGIISR S279-p
Syk (rat) NAHPVTWSPGGIISR S279
S289
GIISRIKSYsFPKPG
2 16
Syk (human) GIISRIKsysFPKPG S295-p
Syk iso2 (human) gap -
Syk (mouse) GIISRIKsysFPKPG S289-p
Syk (rat) GIISRIKSYsFPKPG S289
Y290
IISRIKSYsFPKPGH
3 105
Syk (human) IISRIKsysFPKPGH Y296-p
Syk iso2 (human) gap -
Syk (mouse) IISRIKsysFPKPGH Y290-p
Syk (rat) IISRIKSYsFPKPGH Y290
S291-p
ISRIKSYsFPKPGHK
3 34
Syk (human)
S297-p
Syk (human) ISRIKsysFPKPGHR S297-p
Syk iso2 (human) gap -
Syk (mouse) ISRIKsysFPKPGHK S291-p
Syk (rat) ISRIKSYsFPKPGHK S291-p
S310
PQGSRPESTVSFNPy
0 1
Syk (human) AQGNRQEsTVsFNPy S316-p
Syk iso2 (human) AQGNRQESTVSFNPY S293
Syk (mouse) PQGSRPESTVSFNPy S310
Syk (rat) PQGSRPESTVSFNPy S310
S313
SRPESTVSFNPyEPT
0 3
Syk (human) NRQEsTVsFNPyEPE S319-p
Syk iso2 (human) NRQESTVSFNPYEPE S296
Syk (mouse) SRPESTVSFNPyEPt S313
Syk (rat) SRPESTVSFNPyEPT S313
Y317-p
STVSFNPyEPTGGAW
Upstream
Downstream
18 1048
Syk (human)
Y323-p
Syk (mouse)
Y317-p
Syk (rat)
Y317-p
Effects on Modified Protein
  • enzymatic activity, inhibited
Regulatory protein:
  • LYN (rat)
Treatment
  • anti-FcR1
  • Bay61-3606
  • BIRA766
Syk (human) sTVsFNPyEPELAPW Y323-p
Syk iso2 (human) STVSFNPYEPELAPW Y300
Syk (mouse) STVSFNPyEPtGGPW Y317-p
Syk (rat) STVSFNPyEPTGGAW Y317-p
T320
SFNPyEPTGGAWGPD
0 9
Syk (human) sFNPyEPELAPWAAD E326
Syk iso2 (human) SFNPYEPELAPWAAD E303
Syk (mouse) SFNPyEPtGGPWGPD T320-p
Syk (rat) SFNPyEPTGGAWGPD T320
-
under review
0 1
Syk (human) LAPWAADkGPQREAL K334-ub
Syk iso2 (human) LAPWAADKGPQREAL K311
Syk (mouse) GGPWGPDRGLQREAL R328
Syk (rat) under review -
T339
REALPMDTEVyESPy
0 9
Syk (human) REALPMDtEVyEsPy T345-p
Syk iso2 (human) REALPMDTEVYESPY T322
Syk (mouse) REALPMDTEVyESPy T339
Syk (rat) REALPMDTEVyESPy T339
Y342-p
LPMDTEVyESPyADP
Upstream
Downstream
11 123
Effects on Modified Protein
  • enzymatic activity, induced
Regulatory protein:
  • LYN (rat)
Treatment
  • anti-FcR1
  • antigenic stimulation
  • Bay61-3606
  • BIRA766
  • vanadate
Syk (human) LPMDtEVyEsPyADP Y348-p
Syk iso2 (human) LPMDTEVYESPYADP Y325
Syk (mouse) LPMDTEVyESPyADP Y342-p
Syk (rat) LPMDTEVyESPyADP Y342-p
S344
MDTEVyESPyADPEE
0 7
Syk (human) MDtEVyEsPyADPEE S350-p
Syk iso2 (human) MDTEVYESPYADPEE S327
Syk (mouse) MDTEVyESPyADPEE S344
Syk (rat) MDTEVyESPyADPEE S344
Y346-p
TEVyESPyADPEEIR
Upstream
26 269
Syk (human)
Y352-p
Putative in vivo kinases:
  • LYN (rat)
Regulatory protein:
  • LYN (rat)
Treatment
  • anti-FcR1
  • Bay61-3606
  • BIRA766
Syk (human) tEVyEsPyADPEEIR Y352-p
Syk iso2 (human) TEVYESPYADPEEIR Y329
Syk (mouse) TEVyESPyADPEEIR Y346-p
Syk (rat) TEVyESPyADPEEIR Y346-p
Y358
EIRPKEVYLDRKLLT
1 1
Syk (human) EIRPKEVYLDRKLLT Y364
Syk iso2 (human) EIRPKEVYLDRKLLT Y341
Syk (mouse) EIRPKEVyLDRSLLT Y358-p
Syk (rat) EIRPKEVYLDRKLLT Y358
S373
LEDNELGSGNFGTVK
0 1
Syk (human) LEDKELGSGNFGtVK S379
Syk iso2 (human) LEDKELGSGNFGTVK S356
Syk (mouse) LEDNELGsGNFGTVK S373-p
Syk (rat) LEDNELGSGNFGTVK S373
T378
LGSGNFGTVKKGYYQ
0 1
Syk (human) LGSGNFGtVKKGYYQ T384-p
Syk iso2 (human) LGSGNFGTVKKGYYQ T361
Syk (mouse) LGsGNFGTVKKGyyQ T378
Syk (rat) LGSGNFGTVKKGYYQ T378
Y383
FGTVKKGYYQMKKVV
0 1
Syk (human) FGtVKKGYYQMKkVV Y389
Syk iso2 (human) FGTVKKGYYQMKKVV Y366
Syk (mouse) FGTVKKGyyQMKKVV Y383-p
Syk (rat) FGTVKKGYYQMKKVV Y383
Y384
GTVKKGYYQMKKVVK
0 1
Syk (human) GtVKKGYYQMKkVVK Y390
Syk iso2 (human) GTVKKGYYQMKKVVK Y367
Syk (mouse) GTVKKGyyQMKKVVK Y384-p
Syk (rat) GTVKKGYYQMKKVVK Y384
K388
KGYYQMKKVVKTVAV
0 1
Syk (human) KGYYQMKkVVKTVAV K394-ac
Syk iso2 (human) KGYYQMKKVVKTVAV K371
Syk (mouse) KGyyQMKKVVKTVAV K388
Syk (rat) KGYYQMKKVVKTVAV K388
K396
VVKTVAVKILKNEAN
0 1
Syk (human) VVKTVAVkILKNEAN K402-ac
Syk iso2 (human) VVKTVAVKILKNEAN K379
Syk (mouse) VVKTVAVKILKNEAN K396
Syk (rat) VVKTVAVKILKNEAN K396
T498
ARNVLLVTQHYAKIS
0 1
Syk (human) ARNVLLVtQHyAkIS T504-p
Syk iso2 (human) ARNVLLVTQHYAKIS T481
Syk (mouse) ARNVLLVTQHyAKIS T498
Syk (rat) ARNVLLVTQHYAKIS T498
Y501
VLLVTQHYAKISDFG
1 6
Syk (human) VLLVtQHyAkISDFG Y507-p
Syk iso2 (human) VLLVTQHYAKISDFG Y484
Syk (mouse) VLLVTQHyAKISDFG Y501-p
Syk (rat) VLLVTQHYAKISDFG Y501
K503
LVTQHYAKISDFGLS
0 8
Syk (human) LVtQHyAkISDFGLS K509-ub
Syk iso2 (human) LVTQHYAKISDFGLS K486
Syk (mouse) LVTQHyAKISDFGLS K503
Syk (rat) LVTQHYAKISDFGLS K503
K511
ISDFGLSKALRADEN
0 5
Syk (human) ISDFGLSkALRADEN K517-ub
Syk iso2 (human) ISDFGLSKALRADEN K494
Syk (mouse) ISDFGLSKALRADEN K511
Syk (rat) ISDFGLSKALRADEN K511
Y519-p
ALRADENyyKAQTHG
Upstream
28 82
Syk (human)
Y525-p
Syk (mouse)
Y519-p
Syk (rat)
Y519-p
Kinase, in vitro:
  • Syk (human)
Regulatory protein:
  • LYN (rat)
Treatment
  • anti-FcR1
  • Bay61-3606
  • BIRA766
Syk (human) ALRADENyykAQtHG Y525-p
Syk iso2 (human) ALRADENYYKAQTHG Y502
Syk (mouse) ALRADENyyKAQTHG Y519-p
Syk (rat) ALRADENyyKAQTHG Y519-p
Y520-p
LRADENyyKAQTHGK
Upstream
28 79
Syk (human)
Y526-p
Syk (mouse)
Y520-p
Syk (rat)
Y520-p
Kinase, in vitro:
  • Syk (human)
Regulatory protein:
  • LYN (rat)
Treatment
  • anti-FcR1
  • Bay61-3606
  • BIRA766
Syk (human) LRADENyykAQtHGK Y526-p
Syk iso2 (human) LRADENYYKAQTHGK Y503
Syk (mouse) LRADENyyKAQTHGK Y520-p
Syk (rat) LRADENyyKAQTHGK Y520-p
K521
RADENyyKAQTHGKW
0 1
Syk (human) RADENyykAQtHGKW K527-ub
Syk iso2 (human) RADENYYKAQTHGKW K504
Syk (mouse) RADENyyKAQTHGKW K521
Syk (rat) RADENyyKAQTHGKW K521
T524
ENyyKAQTHGKWPVK
0 1
Syk (human) ENyykAQtHGKWPVK T530-p
Syk iso2 (human) ENYYKAQTHGKWPVK T507
Syk (mouse) ENyyKAQTHGKWPVK T524
Syk (rat) ENyyKAQTHGKWPVK T524
Y533
GKWPVKWYAPECINY
0 1
Syk (human) GKWPVKWyAPECINy Y539-p
Syk iso2 (human) GKWPVKWYAPECINY Y516
Syk (mouse) GKWPVKWYAPECINy Y533
Syk (rat) GKWPVKWYAPECINY Y533
Y540
YAPECINYFKFSSKS
0 3
Syk (human) yAPECINyYKFSSKS Y546-p
Syk iso2 (human) YAPECINYYKFSSKS Y523
Syk (mouse) YAPECINyYKFSSKS Y540-p
Syk (rat) YAPECINYFKFSSKS Y540
K565
EAFSYGQKPYRGMKG
0 2
Syk (human) EAFSYGQkPYRGMKG K571-ac
Syk iso2 (human) EAFSYGQKPYRGMKG K548
Syk (mouse) EAFSYGQkPYRGMKG K565-ac
Syk (rat) EAFSYGQKPYRGMKG K565
S573
PYRGMKGSEVTAMLE
0 1
Syk (human) PYRGMKGsEVTAMLE S579-p
Syk iso2 (human) PYRGMKGSEVTAMLE S556
Syk (mouse) PYRGMKGSEVTAMLE S573
Syk (rat) PYRGMKGSEVTAMLE S573
K581
EVTAMLEKGERMGCP
0 1
Syk (human) EVTAMLEkGERMGCP K587-ub
Syk iso2 (human) EVTAMLEKGERMGCP K564
Syk (mouse) EVTAMLEKGERMGCP K581
Syk (rat) EVTAMLEKGERMGCP K581
Y623-p
VELRLRNyyyDVVN_
2 2
Syk (human) VELRLRNyyyDVVN_ Y629-p
Syk iso2 (human) VELRLRNYYYDVVN_ Y606
Syk (mouse) VELRLRNyyyDVVN_ Y623-p
Syk (rat) VELRLRNyyyDVVN_ Y623-p
Y624-p
ELRLRNyyyDVVN__
Downstream
3 7
Effects on Modified Protein
  • enzymatic activity, induced
  • molecular association, regulation
  • phosphorylation
Syk (human) ELRLRNyyyDVVN__ Y630-p
Syk iso2 (human) ELRLRNYYYDVVN__ Y607
Syk (mouse) ELRLRNyyyDVVN__ Y624-p
Syk (rat) ELRLRNyyyDVVN__ Y624-p
Y625-p
LRLRNyyyDVVN___
Downstream
3 4
Effects on Modified Protein
  • enzymatic activity, induced
  • molecular association, regulation
  • phosphorylation
Syk (human) LRLRNyyyDVVN___ Y631-p
Syk iso2 (human) LRLRNYYYDVVN___ Y608
Syk (mouse) LRLRNyyyDVVN___ Y625-p
Syk (rat) LRLRNyyyDVVN___ Y625-p