Other Species / Isoforms
  IkB-alpha (mouse)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
K21-ub
EGPRDGLkkERLVDD
4 0
IkB-alpha (human) EGPRDGLkkERLLDD K21-ub
IkB-alpha (mouse) EGPRDGLkkERLVDD K21-ub
IkB-alpha (rat) EGPRDGLKKERLVDD K21
K21-sm
EGPRDGLkkERLVDD
4 0
IkB-alpha (human) EGPRDGLkkERLLDD K21-sm
IkB-alpha (mouse) EGPRDGLkkERLVDD K21-sm
IkB-alpha (rat) EGPRDGLKKERLVDD K21
K22-ub
GPRDGLkkERLVDDR
4 0
IkB-alpha (human) GPRDGLkkERLLDDR K22-ub
IkB-alpha (mouse) GPRDGLkkERLVDDR K22-ub
IkB-alpha (rat) GPRDGLKKERLVDDR K22
K22
GPRDGLkKERLVDDR
1 0
IkB-alpha (human) GPRDGLkkERLLDDR K22-sm
IkB-alpha (mouse) GPRDGLkKERLVDDR K22
IkB-alpha (rat) GPRDGLKKERLVDDR K22
S32-p
LVDDRHDsGLDsMKD
Upstream
Downstream
127 19
IkB-alpha (human)
S32-p
IkB-alpha (mouse)
S32-p
IkB-alpha (rat)
S32-p
Effects on Modified Protein
  • protein degradation
Kinase, in vitro:
  • IKKA (mouse)
  • IKKB (mouse)
  • IKKE (mouse)
  • MST1 (mouse)
Putative in vivo kinases:
  • IKKB (mouse)
Regulatory protein:
  • EAR-2 (mouse)
  • GSK3B (human)
  • IKKG (mouse)
  • IL-1RA (mouse)
  • LYN (mouse)
  • SH3BP2 (mouse)
  • TSC2 (mouse)
Treatment
  • 15d-PGJ2
  • 2-AP
  • [6]-gingerol
  • AG17
  • AG490
  • anti-CD40
  • anti-IgM
  • anti-LT(beta)R
  • Aplidin
  • bacterial infection
  • benzo(a)pyrene
  • beta-amyloid_42
  • bortezomib
  • cycloheximide
  • DNP
  • EDA-A1
  • GM-CSF
  • Go_6976
  • guanosine
  • IFN-gamma
  • IgE
  • IKK-beta_inhibitor_IV
  • IL-10
  • IL-1b
  • IMD-0354
  • ionomycin
  • LPS
  • LY294002
  • M-CSF
  • MMS
  • MSP
  • NTCU
  • okadaic_acid
  • partial_hepatectomy
  • peptidoglycan
  • phorbol_ester
  • PIF
  • pomegranate_wine
  • SB203580
  • SC-514
  • TGF-beta
  • TNF
  • U0126
  • virus infection
IkB-alpha (human) LLDDRHDsGLDsMkD S32-p
IkB-alpha (mouse) LVDDRHDsGLDsMKD S32-p
IkB-alpha (rat) LVDDRHDsGLDsMKD S32-p
S36-p
RHDsGLDsMKDEEYE
Upstream
Downstream
84 8
IkB-alpha (human)
S36-p
IkB-alpha (mouse)
S36-p
IkB-alpha (rat)
S36-p
Effects on Modified Protein
  • protein degradation
Kinase, in vitro:
  • IKKA (mouse)
  • IKKB (mouse)
  • IKKE (mouse)
  • MST1 (mouse)
Putative in vivo kinases:
  • IKKB (mouse)
Regulatory protein:
  • GSK3B (human)
  • IKKG (mouse)
  • IL-1RA (mouse)
  • SH3BP2 (mouse)
Treatment
  • [6]-gingerol
  • anti-CD40
  • anti-IgM
  • anti-LT(beta)R
  • Aplidin
  • bacterial infection
  • bortezomib
  • cycloheximide
  • EDA-A1
  • GM-CSF
  • Go_6976
  • IL-10
  • IL-1b
  • ionomycin
  • LPS
  • LY294002
  • M-CSF
  • partial_hepatectomy
  • phorbol_ester
  • PIF
  • SB203580
  • SC-514
  • TNF
  • virus infection
IkB-alpha (human) RHDsGLDsMkDEEyE S36-p
IkB-alpha (mouse) RHDsGLDsMKDEEYE S36-p
IkB-alpha (rat) RHDsGLDsMKDEDyE S36-p
K38
DsGLDsMKDEEYEQM
1 0
IkB-alpha (human) DsGLDsMkDEEyEQM K38-ub
IkB-alpha (mouse) DsGLDsMKDEEYEQM K38
IkB-alpha (rat) DsGLDsMKDEDyEQM K38
Y42
DsMKDEEYEQMVKEL
14 28
IkB-alpha (human) DsMkDEEyEQMVkEL Y42-p
IkB-alpha (mouse) DsMKDEEYEQMVKEL Y42
IkB-alpha (rat) DsMKDEDyEQMVKEL Y42-p
K47
EEYEQMVKELREIRL
1 1
IkB-alpha (human) EEyEQMVkELQEIRL K47-ub
IkB-alpha (mouse) EEYEQMVKELREIRL K47
IkB-alpha (rat) EDyEQMVKELREIRL K47
K67
PLAAEPWKQQLTEDG
0 5
IkB-alpha (human) PRGSEPWkQQLTEDG K67-ub
IkB-alpha (mouse) PLAAEPWKQQLTEDG K67
IkB-alpha (rat) PLAAEPWKQQLTEDG K67
K87
LAIIHEEKPLTMEVI
0 1
IkB-alpha (human) LAIIHEEkALtMEVI K87-ub
IkB-alpha (mouse) LAIIHEEKPLTMEVI K87
IkB-alpha (rat) LAIIHEEKTLTMEVI K87
T90
IHEEKPLTMEVIGQV
0 1
IkB-alpha (human) IHEEkALtMEVIRQV T90-p
IkB-alpha (mouse) IHEEKPLTMEVIGQV T90
IkB-alpha (rat) IHEEKTLTMEVIGQV T90
K98
MEVIGQVKGDLAFLN
0 2
IkB-alpha (human) MEVIRQVkGDLAFLN K98-ub
IkB-alpha (mouse) MEVIGQVKGDLAFLN K98
IkB-alpha (rat) MEVIGQVKGDLAFLN K98
T166
SVAVLTQTCTPQHLH
0 1
IkB-alpha (human) SVGVLTQsCTTPHLH S166-p
IkB-alpha (mouse) SVAVLTQTCTPQHLH T166
IkB-alpha (rat) SVAVLTQTCTPQHLH T166
K238
DLVSLLLKCGADVNR
0 8
IkB-alpha (human) DLVSLLLkCGADVNR K238-ub
IkB-alpha (mouse) DLVSLLLKCGADVNR K238
IkB-alpha (rat) DLVSLLLKCGADVNR K238
Y248-p
ADVNRVTyQGysPYQ
0 1
IkB-alpha (human) ADVNRVTYQGYSPYQ Y248
IkB-alpha (mouse) ADVNRVTyQGysPYQ Y248-p
IkB-alpha (rat) ADVNRVTYQGYSPYQ Y248
Y251-p
NRVTyQGysPYQLTW
0 1
IkB-alpha (human) NRVTYQGYSPYQLTW Y251
IkB-alpha (mouse) NRVTyQGysPYQLTW Y251-p
IkB-alpha (rat) NRVTYQGYSPYQLTW Y251
S252-p
RVTyQGysPYQLTWG
0 1
IkB-alpha (human) RVTYQGYSPYQLTWG S252
IkB-alpha (mouse) RVTyQGysPYQLTWG S252-p
IkB-alpha (rat) RVTYQGYSPYQLTWG S252
S283
NLQMLPESEDEESYD
3 1
IkB-alpha (human) NLQMLPEsEDEEsyD S283-p
IkB-alpha (mouse) NLQMLPESEDEESYD S283
IkB-alpha (rat) NLQTLPESEDEESYD S283
S288
PESEDEESYDTEsEF
1 0
IkB-alpha (human) PEsEDEEsyDtEsEF S288-p
IkB-alpha (mouse) PESEDEESYDTEsEF S288
IkB-alpha (rat) PESEDEESYDTESEF S288
Y289
ESEDEESYDTEsEFT
1 0
IkB-alpha (human) EsEDEEsyDtEsEFT Y289-p
IkB-alpha (mouse) ESEDEESYDTEsEFT Y289
IkB-alpha (rat) ESEDEESYDTESEFT Y289
T291
EDEESYDTEsEFTED
4 0
IkB-alpha (human) EDEEsyDtEsEFTEF T291-p
IkB-alpha (mouse) EDEESYDTEsEFTED T291
IkB-alpha (rat) EDEESYDTESEFTED T291
S293-p
EESYDTEsEFTEDEL
Upstream
Downstream
3 0
Effects on Modified Protein
  • protein degradation
Kinase, in vitro:
  • CK2A1 (mouse)
IkB-alpha (human) EEsyDtEsEFTEFtE S293-p
IkB-alpha (mouse) EESYDTEsEFTEDEL S293-p
IkB-alpha (rat) EESYDTESEFTEDEL S293
T296
YDTEsEFTEDELPYD
2 0
IkB-alpha (human) EsEFTEFtEDELPyD T299-p
IkB-alpha (mouse) YDTEsEFTEDELPYD T296
IkB-alpha (rat) YDTESEFTEDELPYD T296
Y302
FTEDELPYDDCVFGG
3 5
IkB-alpha (human) FtEDELPyDDCVFGG Y305-p
IkB-alpha (mouse) FTEDELPYDDCVFGG Y302
IkB-alpha (rat) FTEDELPYDDCVFGG Y302