Other Species / Isoforms
  IGFBP3 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
T7-p
_MQRARPtLWAAALT
0 1
IGFBP3 (human) _MQRARPtLWAAALT T7-p
IGFBP3 iso2 (human) _MQRARPTLWAAALT T7
IGFBP3 (mouse) _MHPARPALWAAALT A7
IGFBP3 (rat) _MHPARPALWAAALT A7
S138-p
PPAPGNAsEsEEDRs
Upstream
Downstream
3 0
Effects on Biological Processes:
  • apoptosis, induced
Kinase, in vitro:
  • CK2A1 (human)
Putative in vivo kinases:
  • CK2A1 (human)
Regulatory protein:
  • P38A (human)
Treatment
  • BIRB-0796
  • high_glucose
  • TBB
  • TNF
IGFBP3 (human) PPAPGNAsEsEEDRs S138-p
IGFBP3 iso2 (human) PPAPGNASESEEDRS S144
IGFBP3 (mouse) QPAPGNISESEEEHN S139
IGFBP3 (rat) QPSPGNTTESEEDHN T139
S140-p
APGNAsEsEEDRsAG
Upstream
Downstream
3 0
Effects on Biological Processes:
  • apoptosis, induced
Kinase, in vitro:
  • CK2A1 (human)
Putative in vivo kinases:
  • CK2A1 (human)
Regulatory protein:
  • P38A (human)
Treatment
  • BIRB-0796
  • high_glucose
  • TBB
  • TNF
IGFBP3 (human) APGNAsEsEEDRsAG S140-p
IGFBP3 iso2 (human) APGNASESEEDRSAG S146
IGFBP3 (mouse) APGNISESEEEHNAG S141
IGFBP3 (rat) SPGNTTESEEDHNAG S141
S145-p
sEsEEDRsAGsVEsP
0 2
IGFBP3 (human) sEsEEDRsAGsVEsP S145-p
IGFBP3 iso2 (human) SESEEDRSAGSVESP S151
IGFBP3 (mouse) SESEEEHNAGSVESQ N146
IGFBP3 (rat) TESEEDHNAGSVESQ N146
S148-p
EEDRsAGsVEsPsVs
0 4
IGFBP3 (human) EEDRsAGsVEsPsVs S148-p
IGFBP3 iso2 (human) EEDRSAGSVESPSVS S154
IGFBP3 (mouse) EEEHNAGSVESQVVP S149
IGFBP3 (rat) EEDHNAGSVESQVVP S149
S148-ga
EEDRsAGsVEsPsVs
0 1
IGFBP3 (human) EEDRsAGsVEsPsVs S148-ga
IGFBP3 iso2 (human) EEDRSAGSVESPSVS S154
IGFBP3 (mouse) EEEHNAGSVESQVVP S149
IGFBP3 (rat) EEDHNAGSVESQVVP S149
S151-p
RsAGsVEsPsVsstH
0 1
IGFBP3 (human) RsAGsVEsPsVsstH S151-p
IGFBP3 iso2 (human) RSAGSVESPSVSSTH S157
IGFBP3 (mouse) HNAGSVESQVVPSTH S152
IGFBP3 (rat) HNAGSVESQVVPSTH S152
S151-ga
RsAGsVEsPsVsstH
0 1
IGFBP3 (human) RsAGsVEsPsVsstH S151-ga
IGFBP3 iso2 (human) RSAGSVESPSVSSTH S157
IGFBP3 (mouse) HNAGSVESQVVPSTH S152
IGFBP3 (rat) HNAGSVESQVVPSTH S152
S153-ga
AGsVEsPsVsstHRV
0 1
IGFBP3 (human) AGsVEsPsVsstHRV S153-ga
IGFBP3 iso2 (human) AGSVESPSVSSTHRV S159
IGFBP3 (mouse) AGSVESQVVPSTHRV V154
IGFBP3 (rat) AGSVESQVVPSTHRV V154
S155-ga
sVEsPsVsstHRVsD
0 1
IGFBP3 (human) sVEsPsVsstHRVsD S155-ga
IGFBP3 iso2 (human) SVESPSVSSTHRVSD S161
IGFBP3 (mouse) SVESQVVPSTHRVTD P156
IGFBP3 (rat) SVESQVVPSTHRVTD P156
S156-p
VEsPsVsstHRVsDP
Upstream
Downstream
1 0
Effects on Biological Processes:
  • apoptosis, inhibited
Treatment
  • pioglitazone
IGFBP3 (human) VEsPsVsstHRVsDP S156-p
IGFBP3 iso2 (human) VESPSVSSTHRVSDP S162
IGFBP3 (mouse) VESQVVPSTHRVTDS S157
IGFBP3 (rat) VESQVVPSTHRVTDS S157
S156-ga
VEsPsVsstHRVsDP
0 1
IGFBP3 (human) VEsPsVsstHRVsDP S156-ga
IGFBP3 iso2 (human) VESPSVSSTHRVSDP S162
IGFBP3 (mouse) VESQVVPSTHRVTDS S157
IGFBP3 (rat) VESQVVPSTHRVTDS S157
T157-ga
EsPsVsstHRVsDPK
0 1
IGFBP3 (human) EsPsVsstHRVsDPK T157-ga
IGFBP3 iso2 (human) ESPSVSSTHRVSDPK T163
IGFBP3 (mouse) ESQVVPSTHRVTDSk T158
IGFBP3 (rat) ESQVVPSTHRVTDSK T158
S161-ga
VsstHRVsDPKFHPL
0 1
IGFBP3 (human) VsstHRVsDPKFHPL S161-ga
IGFBP3 iso2 (human) VSSTHRVSDPKFHPL S167
IGFBP3 (mouse) VPSTHRVTDSkFHPL T162
IGFBP3 (rat) VPSTHRVTDSKFHPL T162
K164
tHRVsDPKFHPLHsK
0 1
IGFBP3 (human) tHRVsDPKFHPLHsK K164
IGFBP3 iso2 (human) THRVSDPKFHPLHSK K170
IGFBP3 (mouse) THRVTDSkFHPLHAK K165-ac
IGFBP3 (rat) THRVTDSKFHPLHSK K165
S170-p
PKFHPLHsKIIIIKK
0 1
IGFBP3 (human) PKFHPLHsKIIIIKK S170-p
IGFBP3 iso2 (human) PKFHPLHSKIIIIKK S176
IGFBP3 (mouse) SkFHPLHAKMDVIKK A171
IGFBP3 (rat) SKFHPLHSKMEVIIK S171
S183-p
KKGHAKDsQRYKVDy
Upstream
Downstream
2 0
Effects on Modified Protein
  • intracellular localization
Effects on Biological Processes:
  • apoptosis, altered
  • apoptosis, inhibited
  • cell growth, induced
Putative in vivo kinases:
  • DNAPK (human)
IGFBP3 (human) KKGHAKDsQRYKVDy S183-p
IGFBP3 iso2 (human) KKGHAKDSQRYKVDY S189
IGFBP3 (mouse) KKGHARDSQRYKVDY S184
IGFBP3 (rat) IKGQARDSQRYKVDY S184
Y190-p
sQRYKVDyEsQstDt
0 1
IGFBP3 (human) sQRYKVDyEsQstDt Y190-p
IGFBP3 iso2 (human) SQRYKVDYESQSTDT Y196
IGFBP3 (mouse) SQRYKVDYESQSTDT Y191
IGFBP3 (rat) SQRYKVDYESQSTDT Y191
S192-ga
RYKVDyEsQstDtQN
0 1
IGFBP3 (human) RYKVDyEsQstDtQN S192-ga
IGFBP3 iso2 (human) RYKVDYESQSTDTQN S198
IGFBP3 (mouse) RYKVDYESQSTDTQn S193
IGFBP3 (rat) RYKVDYESQSTDTQN S193
S194-p
KVDyEsQstDtQNFs
Upstream
Downstream
1 0
Effects on Modified Protein
  • phosphorylation
Effects on Biological Processes:
  • apoptosis, altered
Putative in vivo kinases:
  • CK2A1 (human)
Treatment
  • DMAT
  • TBB
IGFBP3 (human) KVDyEsQstDtQNFs S194-p
IGFBP3 iso2 (human) KVDYESQSTDTQNFS S200
IGFBP3 (mouse) KVDYESQSTDTQnFS S195
IGFBP3 (rat) KVDYESQSTDTQNFS S195
T195-ga
VDyEsQstDtQNFsS
0 1
IGFBP3 (human) VDyEsQstDtQNFsS T195-ga
IGFBP3 iso2 (human) VDYESQSTDTQNFSS T201
IGFBP3 (mouse) VDYESQSTDTQnFSS T196
IGFBP3 (rat) VDYESQSTDTQNFSS T196
T197-p
yEsQstDtQNFsSES
0 2
IGFBP3 (human) yEsQstDtQNFsSES T197-p
IGFBP3 iso2 (human) YESQSTDTQNFSSES T203
IGFBP3 (mouse) YESQSTDTQnFSSES T198
IGFBP3 (rat) YESQSTDTQNFSSES T198
N199
sQstDtQNFsSESKR
0 1
IGFBP3 (human) sQstDtQNFsSESKR N199
IGFBP3 iso2 (human) SQSTDTQNFSSESKR N205
IGFBP3 (mouse) SQSTDTQnFSSESKR N200-ng
IGFBP3 (rat) SQSTDTQNFSSESKR N200
S201-p
stDtQNFsSESKRET
Upstream
0 4
Treatment
  • selumetinib
IGFBP3 (human) stDtQNFsSESKRET S201-p
IGFBP3 iso2 (human) STDTQNFSSESKRET S207
IGFBP3 (mouse) STDTQnFSSESKRET S202
IGFBP3 (rat) STDTQNFSSESKRET S202
Y210-p
ESKRETEyGPCRREM
0 1
IGFBP3 (human) ESKRETEyGPCRREM Y210-p
IGFBP3 iso2 (human) ESKRETEYGPCRREM Y216
IGFBP3 (mouse) ESKRETEYGPCRREM Y211
IGFBP3 (rat) ESKRETEYGPCRREM Y211
S231-p
LKFLNVLsPRGVHIP
0 1
IGFBP3 (human) LKFLNVLsPRGVHIP S231-p
IGFBP3 iso2 (human) LKFLNVLSPRGVHIP S237
IGFBP3 (mouse) LKFLNVLSPRGVHIP S232
IGFBP3 (rat) LKFLNVLSPRGVHIP S232
Y246-p
NCDKKGFyKKKQCRP
0 1
IGFBP3 (human) NCDKKGFyKKKQCRP Y246-p
IGFBP3 iso2 (human) NCDKKGFYKKKQCRP Y252
IGFBP3 (mouse) NCDKKGFYKKKQCRP Y247
IGFBP3 (rat) NCDKKGFYKKKQCRP Y247
T277-ga
QPLPGYTtKGKEDVH
0 1
IGFBP3 (human) QPLPGYTtKGKEDVH T277-ga
IGFBP3 iso2 (human) QPLPGYTTKGKEDVH T283
IGFBP3 (mouse) QPLPGYDTKGKDDVH T278
IGFBP3 (rat) QPLPGYDTKGKDDVH T278
S290
VHCYSMQSK______
0 1
IGFBP3 (human) VHCYSMQSK______ S290
IGFBP3 iso2 (human) VHCYSMQSK______ S296
IGFBP3 (mouse) VHCLSVQsQ______ S291-p
IGFBP3 (rat) VHCLSVQSQ______ S291