Other Species / Isoforms
  SHC3 iso2 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
-
gap
0 2
SHC3 (human) ATPAAAPyLVSGEAL Y46-p
SHC3 iso2 (human) gap -
SHC3 (mouse) gap -
SHC3 (rat) AEPAASPYLVSGEAL Y43
T22-p
IRLLIRLtIGLERPP
0 2
SHC3 (human) ERAGARLSGSCSAPS S97
SHC3 iso2 (human) IRLLIRLtIGLERPP T22-p
SHC3 (mouse) gap -
SHC3 (rat) ERAGARLsGSCsAPS S94-p
-
gap
0 1
SHC3 (human) ARLSGSCSAPSLAAP S101
SHC3 iso2 (human) gap -
SHC3 (mouse) gap -
SHC3 (rat) ARLsGSCsAPSLAAP S98-p
-
gap
0 1
SHC3 (human) AAPDGSAPSAPRAPA P113
SHC3 iso2 (human) gap -
SHC3 (mouse) gap -
SHC3 (rat) APDGGSAtPGSRAPA T111-p
-
gap
0 1
SHC3 (human) gap -
SHC3 iso2 (human) gap -
SHC3 (mouse) gap -
SHC3 (rat) GSRAPAAsMsATRKS S120-p
-
gap
0 1
SHC3 (human) APRAPAMSAARKGRP S122
SHC3 iso2 (human) gap -
SHC3 (mouse) ______MSATRKSRA S2
SHC3 (rat) RAPAAsMsATRKSRA S122-p
S87
KPPSKMLSSILGKSN
0 1
SHC3 (human) KPPSKMLsSILGKSN S210-p
SHC3 iso2 (human) KPPSKMLSSILGKSN S87
SHC3 (mouse) KPPSKMLSSILGKSN S90
SHC3 (rat) KPPSKMLSSILGKSN S210
S101
NLQFAGMSISLTIST
0 1
SHC3 (human) NLQFAGMsISLTIST S224-p
SHC3 iso2 (human) NLQFAGMSISLTIST S101
SHC3 (mouse) NLQFAGMSISLTIST S104
SHC3 (rat) NLQFAGMSISLTIST S224
Y185
FELRFKQYLQCPTKI
0 5
SHC3 (human) FELRFKQyLQCPTKI Y308-p
SHC3 iso2 (human) FELRFKQYLQCPTKI Y185
SHC3 (mouse) FELRFKQYLQCPSKV Y188
SHC3 (rat) FELRFKQYLQCPSKI Y308
S201
ALHDRMQSLDEPWTE
0 2
SHC3 (human) ALHDRMQSLDEPWTE S324
SHC3 iso2 (human) ALHDRMQSLDEPWTE S201
SHC3 (mouse) ALQDRMQsLDEPWTE S204-p
SHC3 (rat) ALQDRMQSLDEPWTE S324
S214
TEEEGDGSDHPyyNS
0 3
SHC3 (human) TEEEGDGsDHPyyNs S337-p
SHC3 iso2 (human) TEEEGDGSDHPyyNS S214
SHC3 (mouse) TEEEGDGPDHPYYNS P217
SHC3 (rat) TEEEGDGPDHPyyNS P337
Y218-p
GDGSDHPyyNSIPSK
Upstream
Downstream
3 4
Effects on Modified Protein
  • molecular association, regulation
Kinase, in vitro:
  • EGFR (human)
  • Src (human)
  • TrkA (human)
  • TrkB (human)
SHC3 (human) GDGsDHPyyNsIPSK Y341-p
SHC3 iso2 (human) GDGSDHPyyNSIPSK Y218-p
SHC3 (mouse) GDGPDHPYYNSVPTK Y221
SHC3 (rat) GDGPDHPyyNSVPNK Y341-p
Y219-p
DGSDHPyyNSIPSKM
Upstream
Downstream
3 10
Effects on Modified Protein
  • molecular association, regulation
Kinase, in vitro:
  • EGFR (human)
  • Src (human)
  • TrkA (human)
  • TrkB (human)
SHC3 (human) DGsDHPyyNsIPSKM Y342-p
SHC3 iso2 (human) DGSDHPyyNSIPSKM Y219-p
SHC3 (mouse) DGPDHPYYNSVPTKM Y222
SHC3 (rat) DGPDHPyyNSVPNKM Y342-p
S221
SDHPyyNSIPSKMPP
0 1
SHC3 (human) sDHPyyNsIPSKMPP S344-p
SHC3 iso2 (human) SDHPyyNSIPSKMPP S221
SHC3 (mouse) PDHPYYNSVPTKMPP S224
SHC3 (rat) PDHPyyNSVPNKMPP S344
Y256-p
FAGKEQTyyQGRHLG
Upstream
1 2
Kinase, in vitro:
  • EGFR (human)
  • Src (human)
  • TrkA (human)
  • TrkB (human)
Treatment
  • EGF
  • NGF
SHC3 (human) FAGKEQTyyQGRHLG Y379-p
SHC3 iso2 (human) FAGKEQTyyQGRHLG Y256-p
SHC3 (mouse) FAGKEQTyYQGRHLG Y259-p
SHC3 (rat) FSGKEQTYYQGRHLG Y379
Y257-p
AGKEQTyyQGRHLGD
Upstream
1 4
Kinase, in vitro:
  • EGFR (human)
  • Src (human)
  • TrkA (human)
  • TrkB (human)
Treatment
  • EGF
  • NGF
SHC3 (human) AGKEQTyyQGRHLGD Y380-p
SHC3 iso2 (human) AGKEQTyyQGRHLGD Y257-p
SHC3 (mouse) AGKEQTyYQGRHLGD Y260
SHC3 (rat) SGKEQTYYQGRHLGD Y380
S279
QTPLRQGSSDIySTP
0 2
SHC3 (human) QTPLRQGSSDIysTP S402
SHC3 iso2 (human) QTPLRQGSSDIySTP S279
SHC3 (mouse) RAPTRQGsLDIYSTA S282-p
SHC3 (rat) RAPTRQGSLDIySTP S402
Y283-p
RQGSSDIySTPEGKL
Upstream
Downstream
1 28
Effects on Modified Protein
  • molecular association, regulation
Kinase, in vitro:
  • EGFR (human)
  • Src (human)
  • TrkA (human)
  • TrkB (human)
Treatment
  • EGF
  • NGF
SHC3 (human) RQGSSDIysTPEGKL Y406-p
SHC3 iso2 (human) RQGSSDIySTPEGKL Y283-p
SHC3 (mouse) RQGsLDIYSTAEGKT Y286
SHC3 (rat) RQGSLDIySTPEGKA Y406-p
S284
QGSSDIySTPEGKLH
0 1
SHC3 (human) QGSSDIysTPEGKLH S407-p
SHC3 iso2 (human) QGSSDIySTPEGKLH S284
SHC3 (mouse) QGsLDIYSTAEGKTH S287
SHC3 (rat) QGSLDIySTPEGKAH S407
Y301-p
PTGEAPTyVNTQQIP
Upstream
Downstream
3 1
Effects on Modified Protein
  • activity, induced
  • molecular association, regulation
  • phosphorylation
Effects on Biological Processes:
  • transcription, altered
Kinase, in vitro:
  • EGFR (human)
  • Src (human)
  • TrkA (human)
  • TrkB (human)
SHC3 (human) PTGEAPTyVNTQQIP Y424-p
SHC3 iso2 (human) PTGEAPTyVNTQQIP Y301-p
SHC3 (mouse) PVGETPTYVNTQPVP Y304
SHC3 (rat) PVGETPTYVNTQPVP Y424
S351
PVLSKAASVECISPV
0 15
SHC3 (human) PVLSKAAsVECIsPV S474-p
SHC3 iso2 (human) PVLSKAASVECISPV S351
SHC3 (mouse) PMLSKAAsVECIsPV S354-p
SHC3 (rat) PVLSKAASVECISPV S474
S356
AASVECISPVSPRAP
0 10
SHC3 (human) AAsVECIsPVSPRAP S479-p
SHC3 iso2 (human) AASVECISPVSPRAP S356
SHC3 (mouse) AAsVECIsPVtPRAP S359-p
SHC3 (rat) AASVECISPVTPRAP S479
S359
VECISPVSPRAPDAK
0 2
SHC3 (human) VECIsPVSPRAPDAK S482
SHC3 iso2 (human) VECISPVSPRAPDAK S359
SHC3 (mouse) VECIsPVtPRAPDAR T362-p
SHC3 (rat) VECISPVTPRAPDAK T482