Other Species / Isoforms
  PTPN3 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

  HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
Y324-p
EKNVLSQyWTMGsRN
0 2
PTPN3 (human) EKNVLSQyWTMGsRN Y324-p
PTPN3 iso2 (human) EKNVLSQYWTMGSRN Y193
PTPN3 (mouse) EKNVLSQYWTLGSRN Y324
S329-p
SQyWTMGsRNTKKsV
0 1
PTPN3 (human) SQyWTMGsRNTKKsV S329-p
PTPN3 iso2 (human) SQYWTMGSRNTKKSV S198
PTPN3 (mouse) SQYWTLGSRNPKKsV S329
S335-p
GsRNTKKsVNNQYCK
0 3
PTPN3 (human) GsRNTKKsVNNQYCK S335-p
PTPN3 iso2 (human) GSRNTKKSVNNQYCK S204
PTPN3 (mouse) GSRNPKKsVNNQYCK S335-p
S357-p
WNPAMRRsLsVEHLE
Upstream
0 20
Treatment
  • ischemia
  • selumetinib
  • vemurafenib
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PTPN3 (human) WNPAMRRsLsVEHLE S357-p
PTPN3 iso2 (human) WNPAMRRSLSVEHLE S226
PTPN3 (mouse) WNPVMRRsLsVERLE S357-p
S359-p
PAMRRsLsVEHLETK
Upstream
Downstream
1 25
Effects on Modified Protein
  • molecular association, regulation
Kinase, in vitro:
  • TAK1 (human)
Treatment
  • ischemia
  • selumetinib
  • vemurafenib
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PTPN3 (human) PAMRRsLsVEHLETK S359-p
PTPN3 iso2 (human) PAMRRSLSVEHLETK S228
PTPN3 (mouse) PVMRRsLsVERLETK S359-p
S367-p
VEHLETKsLPsRsPP
0 11
PTPN3 (human) VEHLETKsLPsRsPP S367-p
PTPN3 iso2 (human) VEHLETKSLPSRSPP S236
PTPN3 (mouse) VERLETKsLPsRsPP S367-p
S370-p
LETKsLPsRsPPItP
0 2
PTPN3 (human) LETKsLPsRsPPItP S370-p
PTPN3 iso2 (human) LETKSLPSRSPPITP S239
PTPN3 (mouse) LETKsLPsRsPPItP S370-p
S372-p
TKsLPsRsPPItPNW
Upstream
1 14
Treatment
  • ischemia
PTPN3 (human) TKsLPsRsPPItPNW S372-p
PTPN3 iso2 (human) TKSLPSRSPPITPNW S241
PTPN3 (mouse) TKsLPsRsPPItPNW S372-p
T376-p
PsRsPPItPNWRsPR
1 16
PTPN3 (human) PsRsPPItPNWRsPR T376-p
PTPN3 iso2 (human) PSRSPPITPNWRSPR T245
PTPN3 (mouse) PsRsPPItPNWRsPR T376-p
S381-p
PItPNWRsPRLRHEI
1 11
PTPN3 (human) PItPNWRsPRLRHEI S381-p
PTPN3 iso2 (human) PITPNWRSPRLRHEI S250
PTPN3 (mouse) PItPNWRsPRLRHEI S381-p
S394-p
EIRKPRHssADNLAN
0 1
PTPN3 (human) EIRKPRHssADNLAN S394-p
PTPN3 iso2 (human) EIRKPRHSSADNLAN S263
PTPN3 (mouse) EIRKPRHSSADNLAN S394
S395-p
IRKPRHssADNLANE
0 1
PTPN3 (human) IRKPRHssADNLANE S395-p
PTPN3 iso2 (human) IRKPRHSSADNLANE S264
PTPN3 (mouse) IRKPRHSSADNLANE S395
A421
YTYKGSLAPQDsDsE
0 1
PTPN3 (human) YTYKGSLAPQDsDsE A421
PTPN3 iso2 (human) YTYKGSLAPQDSDSE A290
PTPN3 (mouse) YTYKGPLsPKDsDSE S421-p
S425-p
GSLAPQDsDsEVSQN
0 11
PTPN3 (human) GSLAPQDsDsEVSQN S425-p
PTPN3 iso2 (human) GSLAPQDSDSEVSQN S294
PTPN3 (mouse) GPLsPKDsDSEVSQN S425-p
S427-p
LAPQDsDsEVSQNRS
0 2
PTPN3 (human) LAPQDsDsEVSQNRS S427-p
PTPN3 iso2 (human) LAPQDSDSEVSQNRS S296
PTPN3 (mouse) LsPKDsDSEVSQNHS S427
S455-p
SYLTQKSsSSVsPSS
Upstream
0 1
Treatment
  • rapamycin
PTPN3 (human) SYLTQKSsSSVsPSS S455-p
PTPN3 iso2 (human) SYLTQKSSSSVSPSS S324
PTPN3 (mouse) SCLTQKSSSSVSPSS S455
S459-p
QKSsSSVsPSSNAPG
Upstream
Downstream
2 1
Effects on Modified Protein
  • enzymatic activity, induced
  • protein stabilization
Effects on Biological Processes:
  • apoptosis, inhibited
  • carcinogenesis, induced
  • cell growth, induced
Kinase, in vitro:
  • P38G (human)
Putative in vivo kinases:
  • P38G (human)
Treatment
  • arsenite
  • EGF
  • MKK6DD
  • phorbol_ester
  • pirfenidone
  • SB203580
  • siRNA
  • sorbitol
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PTPN3 (human) QKSsSSVsPSSNAPG S459-p
PTPN3 iso2 (human) QKSSSSVSPSSNAPG S328
PTPN3 (mouse) QKSSSSVSPSSNAPG S459
S469-p
SNAPGSCsPDGVDQQ
1 2
PTPN3 (human) SNAPGSCsPDGVDQQ S469-p
PTPN3 iso2 (human) SNAPGSCSPDGVDQQ S338
PTPN3 (mouse) SNAPGSCSPDGVDQR S469
K486-ub
DDFHRVTkGGsTEDA
0 1
PTPN3 (human) DDFHRVTkGGsTEDA K486-ub
PTPN3 iso2 (human) DDFHRVTKGGSTEDA K355
PTPN3 (mouse) EDYHKVTKGGFVEDA K486
S489-p
HRVTkGGsTEDASQY
0 2
PTPN3 (human) HRVTkGGsTEDASQY S489-p
PTPN3 iso2 (human) HRVTKGGSTEDASQY S358
PTPN3 (mouse) HKVTKGGFVEDASQY F489
K526-ac
GKFGFNLkGGVDQKM
0 1
PTPN3 (human) GKFGFNLkGGVDQKM K526-ac
PTPN3 iso2 (human) GKFGFNLKGGVDQKM K395
PTPN3 (mouse) GRFGFNLKGGVDQKM K526
K677-ub
NLDKNRYkDVLPyDt
0 1
PTPN3 (human) NLDKNRYkDVLPyDt K677-ub
PTPN3 iso2 (human) NLDKNRYKDVLPYDT K546
PTPN3 (mouse) NLDKNRYKDVLPYDT K677
Y682-p
RYkDVLPyDtTRVLL
0 1
PTPN3 (human) RYkDVLPyDtTRVLL Y682-p
PTPN3 iso2 (human) RYKDVLPYDTTRVLL Y551
PTPN3 (mouse) RYKDVLPYDTTRVLL Y682
T684-p
kDVLPyDtTRVLLQG
0 1
PTPN3 (human) kDVLPyDtTRVLLQG T684-p
PTPN3 iso2 (human) KDVLPYDTTRVLLQG T553
PTPN3 (mouse) KDVLPYDTTRVLLQG T684
S835-p
VRSLRVDsEPVLVHC
Downstream
1 1
Effects on Modified Protein
  • molecular association, regulation
PTPN3 (human) VRSLRVDsEPVLVHC S835-p
PTPN3 iso2 (human) VRSLRVDSEPVLVHC S704
PTPN3 (mouse) VRSLRVDGEPALVHC G835