Other Species / Isoforms
  fascin (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

  HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
Y23-p
LINCGNKyLTAEAFG
Upstream
Downstream
1 3
Effects on Biological Processes:
  • cell growth, inhibited
  • cell motility, inhibited
  • cytoskeletal reorganization
Treatment
  • Su11274
fascin (human) LINCGNKyLTAEAFG Y23-p
fascin (mouse) LISCGNKYLTAEAFG Y23
fascin (rat) LISCGNKYLTAEAFG Y23
S38-p
FKVNASAssLkkkQI
Downstream
1 6
Effects on Biological Processes:
  • cell growth, inhibited
  • cell motility, inhibited
  • cytoskeletal reorganization
fascin (human) FKVNASAssLkkkQI S38-p
fascin (mouse) FKVNASAssLkkKQI S38-p
fascin (rat) FKVNASASSLKKKQI S38
S39-p
KVNASAssLkkkQIW
Upstream
Downstream
13 13
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
  • protein conformation
Effects on Biological Processes:
  • cell growth, inhibited
  • cell motility, inhibited
  • cytoskeletal reorganization
Kinase, in vitro:
  • PKCA (human)
Putative in vivo kinases:
  • PKCA (human)
Treatment
  • bisindolylmaleimide
  • phorbol_ester
fascin (human) KVNASAssLkkkQIW S39-p
fascin (mouse) KVNASAssLkkKQIW S39-p
fascin (rat) KVNASASSLKKKQIW S39
K41-ac
NASAssLkkkQIWTL
0 19
fascin (human) NASAssLkkkQIWTL K41-ac
fascin (mouse) NASAssLkkKQIWTL K41-ac
fascin (rat) NASASSLKKKQIWTL K41
K41-ub
NASAssLkkkQIWTL
Downstream
1 7
Effects on Biological Processes:
  • cytoskeletal reorganization
fascin (human) NASAssLkkkQIWTL K41-ub
fascin (mouse) NASAssLkkKQIWTL K41-ub
fascin (rat) NASASSLKKKQIWTL K41
K41-sc
NASAssLkkkQIWTL
0 1
fascin (human) NASAssLkkkQIWTL K41-sc
fascin (mouse) NASAssLKkKQIWTL K41
fascin (rat) NASASSLKKKQIWTL K41
K42-ub
ASAssLkkkQIWTLE
Downstream
1 2
Effects on Biological Processes:
  • cytoskeletal reorganization
fascin (human) ASAssLkkkQIWTLE K42-ub
fascin (mouse) ASAssLkkKQIWTLE K42-ub
fascin (rat) ASASSLKKKQIWTLE K42
K43-ac
SAssLkkkQIWTLEQ
0 1
fascin (human) SAssLkkkQIWTLEQ K43-ac
fascin (mouse) SAssLkkKQIWTLEQ K43
fascin (rat) SASSLKKKQIWTLEQ K43
K43-ub
SAssLkkkQIWTLEQ
0 2
fascin (human) SAssLkkkQIWTLEQ K43-ub
fascin (mouse) SAssLkkKQIWTLEQ K43
fascin (rat) SASSLKKKQIWTLEQ K43
Y69-p
LRSHLGRyLAADkDG
0 1
fascin (human) LRSHLGRyLAADkDG Y69-p
fascin (mouse) LRSHLGRYLAADkDG Y69
fascin (rat) LRSHLGPYLAADKDG Y69
K74-ac
GRyLAADkDGNVtCE
0 9
fascin (human) GRyLAADkDGNVtCE K74-ac
fascin (mouse) GRYLAADKDGNVTCE K74
fascin (rat) GPYLAADKDGNVTCE K74
K74-ub
GRyLAADkDGNVtCE
Upstream
0 11
Treatment
  • adriamycin
  • MG132
fascin (human) GRyLAADkDGNVtCE K74-ub
fascin (mouse) GRYLAADkDGNVTCE K74-ub
fascin (rat) GPYLAADKDGNVTCE K74
K74-sc
GRyLAADkDGNVtCE
0 1
fascin (human) GRyLAADkDGNVtCE K74-sc
fascin (mouse) GRYLAADKDGNVTCE K74
fascin (rat) GPYLAADKDGNVTCE K74
T79-p
ADkDGNVtCEREVPG
0 1
fascin (human) ADkDGNVtCEREVPG T79-p
fascin (mouse) ADkDGNVTCEREVPD T79
fascin (rat) ADKDGNVTCEREVPD T79
Y111-p
QSEAHRRyFGGTEDr
0 3
fascin (human) QSEAHRRyFGGTEDr Y111-p
fascin (mouse) QSEAHRRYFGGTEDR Y111
fascin (rat) QSEAHRRYFGGTEDR Y111
R118-m1
yFGGTEDrLsCFAQT
0 1
fascin (human) yFGGTEDrLsCFAQT R118-m1
fascin (mouse) YFGGTEDRLSCFAQS R118
fascin (rat) YFGGTEDRLSCFAQS R118
S120-p
GGTEDrLsCFAQTVs
0 2
fascin (human) GGTEDrLsCFAQTVs S120-p
fascin (mouse) GGTEDRLSCFAQSVS S120
fascin (rat) GGTEDRLSCFAQSVS S120
S127-p
sCFAQTVsPAEKWSV
0 3
fascin (human) sCFAQTVsPAEKWSV S127-p
fascin (mouse) SCFAQSVSPAEKWSV S127
fascin (rat) SCFAQSVSPAEKWSV S127
Y145-p
MHPQVNIysVtRKRY
0 2
fascin (human) MHPQVNIysVtRKRY Y145-p
fascin (mouse) MHPQVNIYSVTRKRY Y145
fascin (rat) MHPQVNIYSVTRKRY Y145
S146-p
HPQVNIysVtRKRYA
0 1
fascin (human) HPQVNIysVtRKRYA S146-p
fascin (mouse) HPQVNIYSVTRKRYA S146
fascin (rat) HPQVNIYSVTRKRYA S146
T148-p
QVNIysVtRKRYAHL
0 2
fascin (human) QVNIysVtRKRYAHL T148-p
fascin (mouse) QVNIYSVTRKRYAHL T148
fascin (rat) QVNIYSVTRKRYAHL T148
R217-m1
TGYTLEFrsGKVAFR
0 1
fascin (human) TGYTLEFrsGKVAFR R217-m1
fascin (mouse) TGFTLEFRSGkVAFR R217
fascin (rat) TGFTLEFRSGKVAFR R217
S218-p
GYTLEFrsGKVAFRD
0 1
fascin (human) GYTLEFrsGKVAFRD S218-p
fascin (mouse) GFTLEFRSGkVAFRD S218
fascin (rat) GFTLEFRSGKVAFRD S218
K220
TLEFrsGKVAFRDCE
0 1
fascin (human) TLEFrsGKVAFRDCE K220
fascin (mouse) TLEFRSGkVAFRDCE K220-ub
fascin (rat) TLEFRSGKVAFRDCE K220
S234-p
EGRYLAPsGPsGtLk
0 2
fascin (human) EGRYLAPsGPsGtLk S234-p
fascin (mouse) EGRYLAPSGPSGTLk S234
fascin (rat) EGRYLAPSGPSGTLK S234
S237-p
YLAPsGPsGtLkAGK
0 1
fascin (human) YLAPsGPsGtLkAGK S237-p
fascin (mouse) YLAPSGPSGTLkAGK S237
fascin (rat) YLAPSGPSGTLKAGK S237
T239-p
APsGPsGtLkAGKAT
0 3
fascin (human) APsGPsGtLkAGKAT T239-p
fascin (mouse) APSGPSGTLkAGKAT T239
fascin (rat) APSGPSGTLKAGKAT T239
K241-ub
sGPsGtLkAGKATkV
1 13
fascin (human) sGPsGtLkAGKATkV K241-ub
fascin (mouse) SGPSGTLkAGKATKV K241-ub
fascin (rat) SGPSGTLKAGKATKV K241
K241-sc
sGPsGtLkAGKATkV
0 1
fascin (human) sGPsGtLkAGKATkV K241-sc
fascin (mouse) SGPSGTLKAGKATKV K241
fascin (rat) SGPSGTLKAGKATKV K241
K247-ub
LkAGKATkVGkDELF
Downstream
1 3
Effects on Biological Processes:
  • cytoskeletal reorganization
fascin (human) LkAGKATkVGkDELF K247-ub
fascin (mouse) LkAGKATKVGKDELF K247
fascin (rat) LKAGKATKVGKDELF K247
K250-ac
GKATkVGkDELFALE
0 1
fascin (human) GKATkVGkDELFALE K250-ac
fascin (mouse) GKATKVGKDELFALE K250
fascin (rat) GKATKVGKDELFALE K250
K250-ub
GKATkVGkDELFALE
Downstream
1 2
Effects on Biological Processes:
  • cytoskeletal reorganization
fascin (human) GKATkVGkDELFALE K250-ub
fascin (mouse) GKATKVGKDELFALE K250
fascin (rat) GKATKVGKDELFALE K250
S274-p
AANERNVsTRQGMDL
Downstream
1 0
Effects on Biological Processes:
  • cell growth, inhibited
  • cytoskeletal reorganization
fascin (human) AANERNVsTRQGMDL S274-p
fascin (mouse) AANERNVSTRQGMDL S274
fascin (rat) AANERNVSTRQGMDL S274
K304-ac
EIDRDTKkCAFRTHT
0 1
fascin (human) EIDRDTKkCAFRTHT K304-ac
fascin (mouse) EIDRDTRKCAFRTHT K304
fascin (rat) EIDRDTRKCAFRTHT K304
K313-ub
AFRTHTGkyWTLTAT
0 1
fascin (human) AFRTHTGkyWTLTAT K313-ub
fascin (mouse) AFRTHTGKYWTLTAT K313
fascin (rat) AFRTHTGKYWTLTAT K313
Y314-p
FRTHTGkyWTLTATG
0 1
fascin (human) FRTHTGkyWTLTATG Y314-p
fascin (mouse) FRTHTGKYWTLTATG Y314
fascin (rat) FRTHTGKYWTLTATG Y314
S333-p
TASSKNAsCYFDIEW
0 1
fascin (human) TASSKNAsCYFDIEW S333-p
fascin (mouse) TASTKNASCYFDIEW S333
fascin (rat) TASTKNASCYFDIEW S333
K353-m2
TLRASNGkFVTSKkN
0 1
fascin (human) TLRASNGkFVTSKkN K353-m2
fascin (mouse) TLRASNGKFVTAKKN K353
fascin (rat) TLRASNGKFVTAKKN K353
K353-ac
TLRASNGkFVTSKkN
0 3
fascin (human) TLRASNGkFVTSKkN K353-ac
fascin (mouse) TLRASNGKFVTAKKN K353
fascin (rat) TLRASNGkFVTAKKN K353-ac
K353-ub
TLRASNGkFVTSKkN
Downstream
1 1
Effects on Biological Processes:
  • cytoskeletal reorganization
fascin (human) TLRASNGkFVTSKkN K353-ub
fascin (mouse) TLRASNGKFVTAKKN K353
fascin (rat) TLRASNGKFVTAKKN K353
K359-ub
GkFVTSKkNGQLAAS
0 1
fascin (human) GkFVTSKkNGQLAAS K359-ub
fascin (mouse) GKFVTAKKNGQLAAS K359
fascin (rat) GkFVTAKKNGQLAAT K359
K399-ub
HGFIGCRkVTGtLDA
Downstream
1 10
Effects on Biological Processes:
  • cytoskeletal reorganization
fascin (human) HGFIGCRkVTGtLDA K399-ub
fascin (mouse) HGFIGCRkVTGtLDA K399-ub
fascin (rat) HGFIGCRKVTGtLDA K399
K399-sm
HGFIGCRkVTGtLDA
0 1
fascin (human) HGFIGCRkVTGtLDA K399-sm
fascin (mouse) HGFIGCRKVTGtLDA K399
fascin (rat) HGFIGCRKVTGtLDA K399
T403-p
GCRkVTGtLDANRSS
Upstream
Downstream
1 9
Effects on Modified Protein
  • protein conformation
Effects on Biological Processes:
  • carcinogenesis, inhibited
  • cell growth, inhibited
  • cell motility, inhibited
  • cytoskeletal reorganization
Kinase, in vitro:
  • Akt2 (human)
Putative in vivo kinases:
  • Akt2 (human)
Treatment
  • Akt_inhibitor_VIII
fascin (human) GCRkVTGtLDANRSS T403-p
fascin (mouse) GCRkVTGtLDANRSS T403-p
fascin (rat) GCRKVTGtLDANRSS T403-p
Y411-p
LDANRSSyDVFQLEF
0 1
fascin (human) LDANRSSyDVFQLEF Y411-p
fascin (mouse) LDANRSSYDVFQLEF Y411
fascin (rat) LDANRSSYDVFQLEF Y411
K426-ub
NDGAYNIkDSTGKyW
0 1
fascin (human) NDGAYNIkDSTGKyW K426-ub
fascin (mouse) NDGAYNIKDSTGKYW K426
fascin (rat) NDGAYNIKDSTGKYW K426
Y432-p
IkDSTGKyWTVGSDS
0 1
fascin (human) IkDSTGKyWTVGSDS Y432-p
fascin (mouse) IKDSTGKYWTVGSDS Y432
fascin (rat) IKDSTGKYWTVGSDS Y432
T447-p
AVTSSGDtPVDFFFE
0 1
fascin (human) AVTSSGDtPVDFFFE T447-p
fascin (mouse) SVTSSSDTPVDFFLE T447
fascin (rat) SVTSSSDTPVDFFLE T447
Y458-p
FFFEFCDyNKVAIkV
0 1
fascin (human) FFFEFCDyNKVAIkV Y458-p
fascin (mouse) FFLEFCDYNKVALkV Y458
fascin (rat) FFLEFCDYNKVALKV Y458
K464-ub
DyNKVAIkVGGRYLk
1 4
fascin (human) DyNKVAIkVGGRYLk K464-ub
fascin (mouse) DYNKVALkVGGRYLk K464-ub
fascin (rat) DYNKVALKVGGRYLk K464
K464-sc
DyNKVAIkVGGRYLk
0 1
fascin (human) DyNKVAIkVGGRYLk K464-sc
fascin (mouse) DYNKVALKVGGRYLk K464
fascin (rat) DYNKVALKVGGRYLk K464
K471-ub
kVGGRYLkGDHAGVL
Downstream
1 10
Effects on Biological Processes:
  • cytoskeletal reorganization
fascin (human) kVGGRYLkGDHAGVL K471-ub
fascin (mouse) kVGGRYLkGDHAGVL K471-ub
fascin (rat) KVGGRYLKGDHAGVL K471
K471-ac
kVGGRYLkGDHAGVL
Downstream
1 4
Effects on Biological Processes:
  • cell motility, inhibited
  • cytoskeletal reorganization
fascin (human) kVGGRYLkGDHAGVL K471-ac
fascin (mouse) kVGGRYLKGDHAGVL K471
fascin (rat) KVGGRYLkGDHAGVL K471-ac
K471-sc
kVGGRYLkGDHAGVL
0 1
fascin (human) kVGGRYLkGDHAGVL K471-sc
fascin (mouse) kVGGRYLKGDHAGVL K471
fascin (rat) KVGGRYLKGDHAGVL K471
K479-ub
GDHAGVLkASAEtVD
0 3
fascin (human) GDHAGVLkASAEtVD K479-ub
fascin (mouse) GDHAGVLKACAETID K479
fascin (rat) GDHAGVLKACAETID K479
T484-p
VLkASAEtVDPASLW
0 1
fascin (human) VLkASAEtVDPASLW T484-p
fascin (mouse) VLKACAETIDPASLW T484
fascin (rat) VLKACAETIDPATLW T484