Other Species / Isoforms
  PLD2 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
T11
TPESLFPTGDELDSS
2 1
PLD2 (human) TPESLFPTGDELDSS T11
PLD2 (mouse) TQKNLFPyGDyLNSS Y11-p
E14
SLFPTGDELDSSQLQ
1 0
PLD2 (human) SLFPTGDELDSSQLQ E14
PLD2 (mouse) NLFPyGDyLNSSQLH Y14-p
T29-p
MESDEVDtLKEGEDP
0 1
PLD2 (human) MESDEVDtLKEGEDP T29-p
PLD2 (mouse) MEPDEVDTLREGEDP T29
T72-p
VTAQVVGtERYTsGs
1 1
PLD2 (human) VTAQVVGtERYTsGs T72-p
PLD2 (mouse) VIAQVVGTERYTSGS T72
S77-p
VGtERYTsGskVGTC
0 1
PLD2 (human) VGtERYTsGskVGTC S77-p
PLD2 (mouse) VGTERYTSGSKVGTC S77
S79-p
tERYTsGskVGTCTL
0 2
PLD2 (human) tERYTsGskVGTCTL S79-p
PLD2 (mouse) TERYTSGSKVGTCTL S79
K80-ub
ERYTsGskVGTCTLY
0 2
PLD2 (human) ERYTsGskVGTCTLY K80-ub
PLD2 (mouse) ERYTSGSKVGTCTLY K80
T99-p
THGDFSWttKKKYRH
1 1
PLD2 (human) THGDFSWttKKKYRH T99-p
PLD2 (mouse) THGDFTWTTKKKFRH T99
T100-p
HGDFSWttKKKYRHF
1 1
PLD2 (human) HGDFSWttKKKYRHF T100-p
PLD2 (mouse) HGDFTWTTKKKFRHF T100
K118-ub
HRDLLRHkVLMSLLP
0 1
PLD2 (human) HRDLLRHkVLMSLLP K118-ub
PLD2 (mouse) HRDLQRHKVLMSLLP K118
S134-p
ARFAVAYsPARDAGN
Upstream
Downstream
2 6
Effects on Modified Protein
  • enzymatic activity, induced
Putative in vivo kinases:
  • CDK5 (human)
Treatment
  • EGF
PLD2 (human) ARFAVAYsPARDAGN S134-p
PLD2 (mouse) ARFAVTHsPAREAAA S134-p
S146-p
AGNREMPsLPRAGPE
1 5
PLD2 (human) AGNREMPsLPRAGPE S146-p
PLD2 (mouse) AAAEDIPsLPRGGSE S146-p
T156-p
RAGPEGStRHAAsKQ
0 1
PLD2 (human) RAGPEGStRHAAsKQ T156-p
PLD2 (mouse) RGGSEGSARHTASKQ A156
S161-p
GStRHAAsKQKYLEN
0 1
PLD2 (human) GStRHAAsKQKYLEN S161-p
PLD2 (mouse) GSARHTASKQKyLEN S161
Y165
HAAsKQKYLENyLNR
1 0
PLD2 (human) HAAsKQKYLENyLNR Y165
PLD2 (mouse) HTASKQKyLENYLNR Y165-p
Y169-p
KQKYLENyLNRLLtM
Downstream
2 0
Effects on Modified Protein
  • enzymatic activity, induced
  • molecular association, regulation
Effects on Biological Processes:
  • cell growth, altered
  • cell motility, altered
PLD2 (human) KQKYLENyLNRLLtM Y169-p
PLD2 (mouse) KQKyLENYLNRLLTM Y169
T175-p
NyLNRLLtMSFyRNY
Upstream
1 0
Putative in vivo kinases:
  • Akt1 (human)
Treatment
  • LY294002
PLD2 (human) NyLNRLLtMSFyRNY T175-p
PLD2 (mouse) NYLNRLLTMSFYRNY T175
Y179-p
RLLtMSFyRNYHAMT
Downstream
4 0
Effects on Modified Protein
  • enzymatic activity, induced
  • molecular association, regulation
  • phosphorylation
Effects on Biological Processes:
  • cell cycle regulation
  • cell growth, altered
  • cell motility, altered
PLD2 (human) RLLtMSFyRNYHAMT Y179-p
PLD2 (mouse) RLLTMSFYRNYHAMT Y179
S213-p
EGMIRKRsGGHRVPG
0 1
PLD2 (human) EGMIRKRsGGHRVPG S213-p
PLD2 (mouse) EGVIRKRSGGHRVPG S213
S243-p
RWLVVKDsFLLYMCL
Upstream
Downstream
1 1
Effects on Modified Protein
  • enzymatic activity, induced
Putative in vivo kinases:
  • PKCA (human)
Treatment
  • phorbol_ester
PLD2 (human) RWLVVKDsFLLYMCL S243-p
PLD2 (mouse) RWLVVKDSFLLYMRP S243
T252-p
LLYMCLEtGAISFVQ
Upstream
Downstream
1 1
Effects on Modified Protein
  • enzymatic activity, induced
Putative in vivo kinases:
  • PKCA (human)
Treatment
  • phorbol_ester
PLD2 (human) LLYMCLEtGAISFVQ T252-p
PLD2 (mouse) LLYMRPETGAISFVQ T252
K292-m1
SHRSLILkCSSyRQA
0 1
PLD2 (human) SHRSLILkCSSyRQA K292-m1
PLD2 (mouse) SHRSLILKCSSYRQA K292
Y296-p
LILkCSSyRQARWWA
Upstream
Downstream
3 1
Effects on Modified Protein
  • enzymatic activity, induced
  • enzymatic activity, inhibited
Effects on Biological Processes:
  • carcinogenesis, inhibited
  • cell motility, altered
Kinase, in vitro:
  • EGFR (human)
PLD2 (human) LILkCSSyRQARWWA Y296-p
PLD2 (mouse) LILKCSSYRQARWWG Y296
K388-ub
WRLDIMLkRKAEEGV
0 1
PLD2 (human) WRLDIMLkRKAEEGV K388-ub
PLD2 (mouse) WRLDIMLKRKAEEGV K388
K388-m1
WRLDIMLkRKAEEGV
0 2
PLD2 (human) WRLDIMLkRKAEEGV K388-m1
PLD2 (mouse) WRLDIMLKRKAEEGV K388
Y415-p
ALGINSGysKRALML
Upstream
Downstream
5 1
Effects on Modified Protein
  • enzymatic activity, induced
  • molecular association, regulation
Effects on Biological Processes:
  • carcinogenesis, induced
  • cell motility, induced
Kinase, in vitro:
  • JAK3 (human)
Putative in vivo kinases:
  • JAK3 (human)
Treatment
  • siRNA
PLD2 (human) ALGINSGysKRALML Y415-p
PLD2 (mouse) ALGINSGYSKRTLML Y415
S416-p
LGINSGysKRALMLL
0 1
PLD2 (human) LGINSGysKRALMLL S416-p
PLD2 (mouse) LGINSGYSKRTLMLL S416
Y470
GRWDDLHYRLTDLGD
1 0
PLD2 (human) GRWDDLHYRLTDLGD Y470
PLD2 (mouse) GRWDDVQyRLTDLGD Y470-p
T488-p
SAASQPPtPRPDSPA
0 2
PLD2 (human) SAASQPPtPRPDSPA T488-p
PLD2 (mouse) PVHLQTPTLGSDPAA T488
Y511-p
FFWLGKDySNLITKD
Upstream
Downstream
2 1
Effects on Modified Protein
  • enzymatic activity, induced
  • molecular association, regulation
Effects on Biological Processes:
  • cell growth, altered
Kinase, in vitro:
  • Src (human)
PLD2 (human) FFWLGKDySNLITKD Y511-p
PLD2 (mouse) FFWLGKDYSNLITKD Y511
T566-p
FIQRWNFtKTTKAKy
Upstream
Downstream
1 0
Effects on Modified Protein
  • intracellular localization
Effects on Biological Processes:
  • cytoskeletal reorganization
Kinase, in vitro:
  • PKCD (human)
Putative in vivo kinases:
  • PKCD (human)
Treatment
  • fibronectin
PLD2 (human) FIQRWNFtKTTKAKy T566-p
PLD2 (mouse) FIQRWNFTKTTKARY T566
Y573-p
tKTTKAKyKTPTyPy
0 2
PLD2 (human) tKTTKAKyKTPTyPy Y573-p
PLD2 (mouse) TKTTKARYKTPLYPY Y573
Y578-p
AKyKTPTyPyLLPKS
0 1
PLD2 (human) AKyKTPTyPyLLPKS Y578-p
PLD2 (mouse) ARYKTPLYPYLLPKS Y578
Y580-p
yKTPTyPyLLPKSTS
0 2
PLD2 (human) yKTPTyPyLLPKSTS Y580-p
PLD2 (mouse) YKTPLYPYLLPKSTS Y580
K656-ub
DGRTVLNkVGDEIVD
Upstream
0 4
Treatment
  • vorinostat
PLD2 (human) DGRTVLNkVGDEIVD K656-ub
PLD2 (mouse) DGRTVLNKVGDEIVD K656