|
-
|
gap
|
|
|
0
|
1
|
|
|
|
eNOS (human)
|
gap
|
-
|
|
eNOS (mouse)
|
gap
|
-
|
|
eNOS (rat)
|
gap
|
-
|
|
eNOS (rabbit)
|
SPKPSSNSPPLTRPP
|
S62
|
|
eNOS (pig)
|
DHSPAPNSPPLTRPP
|
S58
|
|
eNOS (sheep)
|
DHSPAPSSPTLTRPP
|
S58
|
|
eNOS (cow)
|
DHSPAPNsPTLTRPP
|
S58-p
|
|
|
K5
|
___MGNLKSVGQEPG
|
|
|
0
|
1
|
|
|
|
eNOS (human)
|
___MGNLkSVAQEPG
|
K5-m1
|
|
eNOS (mouse)
|
___MGNLKSVGQEPG
|
K5
|
|
eNOS (rat)
|
___MGNLKSVGQEPG
|
K5
|
|
eNOS (rabbit)
|
___MGNLKSVGQEPG
|
K5
|
|
eNOS (pig)
|
___MGNLKSVAQEPG
|
K5
|
|
eNOS (sheep)
|
___MGNLKSVGQEPG
|
K5
|
|
eNOS (cow)
|
___MGNLKSVGQEPG
|
K5
|
|
|
S33
|
CGKQGPASPAPEPSQ
|
|
|
0
|
1
|
|
|
|
eNOS (human)
|
CGKQGPAtPAPEPSR
|
T33-p
|
|
eNOS (mouse)
|
CGKQGPASPAPEPSQ
|
S33
|
|
eNOS (rat)
|
CGKQGPASPAPEPSQ
|
S33
|
|
eNOS (rabbit)
|
CGKQGPASPAPEPSR
|
S33
|
|
eNOS (pig)
|
CGKQGPASPAPEASQ
|
S33
|
|
eNOS (sheep)
|
CGKQGPASPAPEPSW
|
S33
|
|
eNOS (cow)
|
CGKQGPASPAPEPSR
|
S33
|
|
|
S46
|
SQAPVPPSPTRPAPD
|
|
|
0
|
1
|
|
|
|
eNOS (human)
|
gap
|
-
|
|
eNOS (mouse)
|
SQAPAPPsPtRPAPD
|
S46-p
|
|
eNOS (rat)
|
SQAPVPPSPTRPAPD
|
S46
|
|
eNOS (rabbit)
|
SRAPASPPPTPPAPD
|
P46
|
|
eNOS (pig)
|
gap
|
-
|
|
eNOS (sheep)
|
gap
|
-
|
|
eNOS (cow)
|
gap
|
-
|
|
|
T48
|
APVPPSPTRPAPDHS
|
|
|
0
|
2
|
|
|
|
eNOS (human)
|
gap
|
-
|
|
eNOS (mouse)
|
APAPPsPtRPAPDHs
|
T48-p
|
|
eNOS (rat)
|
APVPPSPTRPAPDHS
|
T48
|
|
eNOS (rabbit)
|
APASPPPTPPAPDHS
|
T48
|
|
eNOS (pig)
|
gap
|
-
|
|
eNOS (sheep)
|
SWAPAPATPQAPDHS
|
T46
|
|
eNOS (cow)
|
SRAPAPAtPHAPDHS
|
T46-p
|
|
|
S55
|
TRPAPDHSPPLTRPP
|
|
|
0
|
3
|
|
|
|
eNOS (human)
|
LPPAPEHsPPSSPLT
|
S53-p
|
|
eNOS (mouse)
|
tRPAPDHsPPLtRPP
|
S55-p
|
|
eNOS (rat)
|
TRPAPDHSPPLTRPP
|
S55
|
|
eNOS (rabbit)
|
TPPAPDHSPKPSSNS
|
S55
|
|
eNOS (pig)
|
PAPAPDHSPAPNSPP
|
S53
|
|
eNOS (sheep)
|
TPQAPDHSPAPSSPT
|
S53
|
|
eNOS (cow)
|
tPHAPDHSPAPNsPT
|
S53
|
|
|
T59
|
PDHSPPLTRPPDGPK
|
|
|
0
|
1
|
|
|
|
eNOS (human)
|
sPPSSPLTQPPEGPK
|
T60
|
|
eNOS (mouse)
|
PDHsPPLtRPPDGPR
|
T59-p
|
|
eNOS (rat)
|
PDHSPPLTRPPDGPK
|
T59
|
|
eNOS (rabbit)
|
SSNSPPLTRPPEGPK
|
T66
|
|
eNOS (pig)
|
APNSPPLTRPPEGPK
|
T62
|
|
eNOS (sheep)
|
APSSPTLTRPPEGPK
|
T62
|
|
eNOS (cow)
|
APNsPTLTRPPEGPK
|
T62
|
|
|
Y80-p
|
WEVGSITyDTLSAQA
|
Upstream
|
|
5
|
1
|
|
|
|
|
|
eNOS (human)
|
WEVGSITyDTLSAQA
|
Y81-p
|
|
eNOS (mouse)
|
WEVGSITyDTLSAQA
|
Y80-p
|
|
eNOS (rat)
|
WEVGSITyDTLSAQA
|
Y80-p
|
|
eNOS (rabbit)
|
WEVGSITYDTLSAQA
|
Y87
|
|
eNOS (pig)
|
WEVGSITYDTLCAQS
|
Y83
|
|
eNOS (sheep)
|
WELGSITYDTLCAQS
|
Y83
|
|
eNOS (cow)
|
WELGSITyDTLCAQS
|
Y83-p
|
|
|
S101
|
TPRRCLGSLVFPRKL
|
|
|
0
|
2
|
|
|
|
eNOS (human)
|
TPRRCLGsLVFPRKL
|
S102-p
|
|
eNOS (mouse)
|
TSRRCLGSLVFPRKL
|
S101
|
|
eNOS (rat)
|
TPRRCLGSLVFPRKL
|
S101
|
|
eNOS (rabbit)
|
TQRRCLGSLVFPRKL
|
S108
|
|
eNOS (pig)
|
TPRRCLGSLVFPRKL
|
S104
|
|
eNOS (sheep)
|
TPRRCLGSLVLPRKL
|
S104
|
|
eNOS (cow)
|
TPRCCLGSLVLPRKL
|
S104
|
|
|
T113
|
RKLQSRPTQGPsPTE
|
|
|
22
|
4
|
|
|
|
|
|
eNOS (human)
|
RKLQGRPsPGPPAPE
|
S114-p
|
|
eNOS (mouse)
|
RKLQSRPTQGPSPTE
|
T113
|
|
eNOS (rat)
|
RKLQSRPTQGPsPTE
|
T113
|
|
eNOS (rabbit)
|
RKLQSRPTQGAPPPE
|
T120
|
|
eNOS (pig)
|
RKLQSRPSQGPPPTE
|
S116
|
|
eNOS (sheep)
|
RKLQTRPSQGPPPAE
|
S116
|
|
eNOS (cow)
|
RKLQTRPsPGPPPAE
|
S116-p
|
|
|
S117-p
|
SRPTQGPsPTEQLLG
|
Upstream
|
|
1
|
0
|
|
|
|
Treatment
- ACh
- beta-amyloid_40
- Go_6976
|
|
|
eNOS (human)
|
GRPsPGPPAPEQLLS
|
P118
|
|
eNOS (mouse)
|
SRPTQGPSPTEQLLG
|
S117
|
|
eNOS (rat)
|
SRPTQGPsPTEQLLG
|
S117-p
|
|
eNOS (rabbit)
|
SRPTQGAPPPEQLLV
|
P124
|
|
eNOS (pig)
|
SRPSQGPPPTEQLLS
|
P120
|
|
eNOS (sheep)
|
TRPSQGPPPAEQLLS
|
P120
|
|
eNOS (cow)
|
TRPsPGPPPAEQLLS
|
P120
|
|
|
Y209
|
TAQEMFTYICNHIKY
|
|
|
0
|
1
|
|
|
|
eNOS (human)
|
SAQEMFTyICNHIKY
|
Y210-p
|
|
eNOS (mouse)
|
TAQEMFTYICNHIKY
|
Y209
|
|
eNOS (rat)
|
TAQEMFTYICNHIKY
|
Y209
|
|
eNOS (rabbit)
|
SAQEMFTYICNHIKY
|
Y216
|
|
eNOS (pig)
|
SAQEMFTYICNHIKY
|
Y212
|
|
eNOS (sheep)
|
SAQEMFTYICNHIKY
|
Y212
|
|
eNOS (cow)
|
SAQEMFTYICNHIKY
|
Y212
|
|
|
S259
|
GYRQQDGSVRGDPAN
|
|
|
0
|
1
|
|
|
|
eNOS (human)
|
GYRQQDGsVRGDPAN
|
S260-p
|
|
eNOS (mouse)
|
GYRQQDGSVRGDPAN
|
S259
|
|
eNOS (rat)
|
GYRQQDGSVRGDPAN
|
S259
|
|
eNOS (rabbit)
|
GYRQQDGSVRGDPAN
|
S266
|
|
eNOS (pig)
|
GYRQQDGSVRGDPAN
|
S262
|
|
eNOS (sheep)
|
GYRQQDGSVRGDPAN
|
S263
|
|
eNOS (cow)
|
GYRQQDGSVRGDPAN
|
S262
|
|
|
S482
|
QPDPWKGSAAKGTGI
|
|
|
0
|
1
|
|
|
|
eNOS (human)
|
QPDPWKGSAAKGTGI
|
S483
|
|
eNOS (mouse)
|
QPDPWKGsAAKGAGI
|
S482-p
|
|
eNOS (rat)
|
QPDPWKGSAAKGTGI
|
S482
|
|
eNOS (rabbit)
|
QPDPWKGSGAKGTGI
|
S489
|
|
eNOS (pig)
|
QPDPWKGSAAKGTGI
|
S485
|
|
eNOS (sheep)
|
QPDPWKGSAAKGAGI
|
S486
|
|
eNOS (cow)
|
QPDPWKGSATKGAGI
|
S485
|
|
|
K493
|
GTGITRKKtFKEVAN
|
|
|
1
|
0
|
|
|
|
eNOS (human)
|
GTGITRKKtFKEVAN
|
K494
|
|
eNOS (mouse)
|
GAGITRKKtFKEVAN
|
K493
|
|
eNOS (rat)
|
GTGITRKKtFKEVAN
|
K493
|
|
eNOS (rabbit)
|
GTGITRKKTFKEVAN
|
K500
|
|
eNOS (pig)
|
GTGIARKKtFKEVAN
|
K496
|
|
eNOS (sheep)
|
GAGITRKKtFKEVAN
|
K497
|
|
eNOS (cow)
|
GAGITRKktFKEVAN
|
K496-ac
|
|
|
T494-p
|
TGITRKKtFKEVANA
|
Upstream
|
Downstream
|
87
|
3
|
|
|
|
|
|
Effects on Modified Protein
- enzymatic activity, inhibited
|
|
|
Kinase, in vitro:
|
|
Putative in vivo kinases:
|
|
Treatment
- ACh
- beta-amyloid_40
- cAMP_analog
- CGP53353
- Go_6976
- H-89
- high-salt diet
- hypoxia
- insulin
- ischemia/reperfusion
- leptin
- MCTP
- okadaic_acid
- Ro31-8220
- ROC-325
- spironolactone
- streptolysin O
- tautomycin
- U0126
|
|
|
eNOS (human)
|
TGITRKKtFKEVANA
|
T495-p
|
|
eNOS (mouse)
|
AGITRKKtFKEVANA
|
T494-p
|
|
eNOS (rat)
|
TGITRKKtFKEVANA
|
T494-p
|
|
eNOS (rabbit)
|
TGITRKKTFKEVANA
|
T501
|
|
eNOS (pig)
|
TGIARKKtFKEVANA
|
T497-p
|
|
eNOS (sheep)
|
AGITRKKtFKEVANA
|
T498-p
|
|
eNOS (cow)
|
AGITRKktFKEVANA
|
T497-p
|
|
|
K503
|
KEVANAVKISASLMG
|
|
|
1
|
0
|
|
|
|
eNOS (human)
|
KEVANAVKISAsLMG
|
K504
|
|
eNOS (mouse)
|
KEVANAVKISASLMG
|
K503
|
|
eNOS (rat)
|
KEVANAVKISASLMG
|
K503
|
|
eNOS (rabbit)
|
KEVANAVKISASLMG
|
K510
|
|
eNOS (pig)
|
KEVANAVKISASLMG
|
K506
|
|
eNOS (sheep)
|
KEVANAVKISASLMG
|
K507
|
|
eNOS (cow)
|
KEVANAVkISASLMG
|
K506-ac
|
|
|
S507
|
NAVKISASLMGTVMA
|
|
|
0
|
2
|
|
|
|
eNOS (human)
|
NAVKISAsLMGtVMA
|
S508-p
|
|
eNOS (mouse)
|
NAVKISASLMGTVMA
|
S507
|
|
eNOS (rat)
|
NAVKISASLMGTVMA
|
S507
|
|
eNOS (rabbit)
|
NAVKISASLMGTVMA
|
S514
|
|
eNOS (pig)
|
NAVKISASLMGTVMA
|
S510
|
|
eNOS (sheep)
|
NAVKISASLMGTLMA
|
S511
|
|
eNOS (cow)
|
NAVkISASLMGTLMA
|
S510
|
|
|
T511
|
ISASLMGTVMAKRVK
|
|
|
0
|
2
|
|
|
|
eNOS (human)
|
ISAsLMGtVMAKRVK
|
T512-p
|
|
eNOS (mouse)
|
ISASLMGTVMAKRVK
|
T511
|
|
eNOS (rat)
|
ISASLMGTVMAKRVK
|
T511
|
|
eNOS (rabbit)
|
ISASLMGTVMAKRVK
|
T518
|
|
eNOS (pig)
|
ISASLMGTVMAKRVK
|
T514
|
|
eNOS (sheep)
|
ISASLMGTLMAKRVK
|
T515
|
|
eNOS (cow)
|
ISASLMGTLMAKRVK
|
T514
|
|
|
S599
|
MSGPYNSSPRPEQHK
|
|
|
1
|
1
|
|
|
|
eNOS (human)
|
MSGPYNSsPRPEQHK
|
S600-p
|
|
eNOS (mouse)
|
MSGPYNSSPRPEQHK
|
S599
|
|
eNOS (rat)
|
MSGPYNSSPRPEQHK
|
S599
|
|
eNOS (rabbit)
|
MSGPYNSSPRPEQHK
|
S606
|
|
eNOS (pig)
|
MSGPYNGSPRPEQHR
|
S602
|
|
eNOS (sheep)
|
MSGPYNSSPRPEQHR
|
S603
|
|
eNOS (cow)
|
MSGPYNSsPRPEQHK
|
S602-p
|
|
|
S614-p
|
SYKIRFNsVSCSDPL
|
Upstream
|
|
13
|
5
|
|
|
|
|
|
eNOS (human)
|
SYKIRFNsISCSDPL
|
S615-p
|
|
eNOS (mouse)
|
SYKIRFNsVSCSDPL
|
S614-p
|
|
eNOS (rat)
|
SYKIRFNsVSCSDPL
|
S614-p
|
|
eNOS (rabbit)
|
SYKIRFNSVSCSDPL
|
S621
|
|
eNOS (pig)
|
SYKIRFNSVSCSDPL
|
S617
|
|
eNOS (sheep)
|
SYKIRFNSVSCSDPL
|
S618
|
|
eNOS (cow)
|
SYKIRFNsVSCSDPL
|
S617-p
|
|
|
S614
|
SYKIRFNSVSCSDPL
|
|
|
1
|
1
|
|
|
|
eNOS (human)
|
SYKIRFNsISCSDPL
|
S615-gl
|
|
eNOS (mouse)
|
SYKIRFNSVSCSDPL
|
S614
|
|
eNOS (rat)
|
SYKIRFNSVSCSDPL
|
S614
|
|
eNOS (rabbit)
|
SYKIRFNSVSCSDPL
|
S621
|
|
eNOS (pig)
|
SYKIRFNSVSCSDPL
|
S617
|
|
eNOS (sheep)
|
SYKIRFNSVSCSDPL
|
S618
|
|
eNOS (cow)
|
SYKIRFNSVSCSDPL
|
S617
|
|
|
S632-p
|
WRRKRKEsSNTDSAG
|
Upstream
|
|
29
|
19
|
|
|
|
Kinase, in vitro:
|
|
Treatment
- endothelin
- high-salt diet
- hypertension
|
|
|
eNOS (human)
|
WRRKRKEssNtDsAG
|
S633-p
|
|
eNOS (mouse)
|
WRRKRKEsSNtDSAG
|
S632-p
|
|
eNOS (rat)
|
WRRKRKEsSNTDSAG
|
S632-p
|
|
eNOS (rabbit)
|
WRRKRKESSNTDSAG
|
S639
|
|
eNOS (pig)
|
WRRKRKESSNTDSAG
|
S635
|
|
eNOS (sheep)
|
WRRKRKESSNTDSAG
|
S636
|
|
eNOS (cow)
|
WRRKRKEsSNTDSAG
|
S635-p
|
|
|
S633
|
RRKRKEsSNTDSAGA
|
|
|
0
|
1
|
|
|
|
eNOS (human)
|
RRKRKEssNtDsAGA
|
S634-p
|
|
eNOS (mouse)
|
RRKRKEsSNtDSAGA
|
S633
|
|
eNOS (rat)
|
RRKRKEsSNTDSAGA
|
S633
|
|
eNOS (rabbit)
|
RRKRKESSNTDSAGA
|
S640
|
|
eNOS (pig)
|
RRKRKESSNTDSAGA
|
S636
|
|
eNOS (sheep)
|
RRKRKESSNTDSAGA
|
S637
|
|
eNOS (cow)
|
RRKRKEsSNTDSAGA
|
S636
|
|
|
T635
|
KRKEsSNTDSAGALG
|
|
|
0
|
2
|
|
|
|
eNOS (human)
|
KRKEssNtDsAGALG
|
T636-p
|
|
eNOS (mouse)
|
KRKEsSNtDSAGALG
|
T635-p
|
|
eNOS (rat)
|
KRKEsSNTDSAGALG
|
T635
|
|
eNOS (rabbit)
|
KRKESSNTDSAGALG
|
T642
|
|
eNOS (pig)
|
KRKESSNTDSAGALG
|
T638
|
|
eNOS (sheep)
|
KRKESSNTDSAGALG
|
T639
|
|
eNOS (cow)
|
KRKEsSNTDSAGALG
|
T638
|
|
|
S637
|
KEsSNTDSAGALGTL
|
|
|
0
|
1
|
|
|
|
eNOS (human)
|
KEssNtDsAGALGTL
|
S638-p
|
|
eNOS (mouse)
|
KEsSNtDSAGALGTL
|
S637
|
|
eNOS (rat)
|
KEsSNTDSAGALGTL
|
S637
|
|
eNOS (rabbit)
|
KESSNTDSAGALGTL
|
S644
|
|
eNOS (pig)
|
KESSNTDSAGALGTL
|
S640
|
|
eNOS (sheep)
|
KESSNTDSAGALGTL
|
S641
|
|
eNOS (cow)
|
KEsSNTDSAGALGTL
|
S640
|
|
|
Y656-p
|
FGLGSRAyPHFCAFA
|
|
|
6
|
1
|
|
|
|
eNOS (human)
|
FGLGSRAyPHFCAFA
|
Y657-p
|
|
eNOS (mouse)
|
FGLGSRAyPHFCAFA
|
Y656-p
|
|
eNOS (rat)
|
FGLGSRAyPHFCAFA
|
Y656-p
|
|
eNOS (rabbit)
|
FGLGSRAYPHFCAFA
|
Y663
|
|
eNOS (pig)
|
FGLGSRAyPHFCAFA
|
Y659-p
|
|
eNOS (sheep)
|
FGLGSRAYPHFCAFA
|
Y660
|
|
eNOS (cow)
|
FGLGSRAYPHFCAFA
|
Y659
|
|
|
S737
|
KRQRYRLSTQAESLQ
|
|
|
0
|
2
|
|
|
|
eNOS (human)
|
KRQRYRLsAQAEGLQ
|
S738-p
|
|
eNOS (mouse)
|
KRQRYRLSTQAESLQ
|
S737
|
|
eNOS (rat)
|
KRQRYRLSTQAESLQ
|
S737
|
|
eNOS (rabbit)
|
KRQRYRLSTQTEGLQ
|
S744
|
|
eNOS (pig)
|
KRQRYRLSAQAEGLQ
|
S740
|
|
eNOS (sheep)
|
KRQRYRLSTQAEGLQ
|
S743
|
|
eNOS (cow)
|
KRQRYRLSTQAEGLQ
|
S740
|
|
|
S737
|
KRQRYRLSTQAESLQ
|
|
|
1
|
0
|
|
|
|
eNOS (human)
|
KRQRYRLsAQAEGLQ
|
S738-gl
|
|
eNOS (mouse)
|
KRQRYRLSTQAESLQ
|
S737
|
|
eNOS (rat)
|
KRQRYRLSTQAESLQ
|
S737
|
|
eNOS (rabbit)
|
KRQRYRLSTQTEGLQ
|
S744
|
|
eNOS (pig)
|
KRQRYRLSAQAEGLQ
|
S740
|
|
eNOS (sheep)
|
KRQRYRLSTQAEGLQ
|
S743
|
|
eNOS (cow)
|
KRQRYRLSTQAEGLQ
|
S740
|
|
|
K772
|
VENLQSSKSTRATIL
|
|
|
0
|
1
|
|
|
|
eNOS (human)
|
VENLQSSkSTRATIL
|
K773-ub
|
|
eNOS (mouse)
|
VENLQSSKSTRATIL
|
K772
|
|
eNOS (rat)
|
VENLQSSKSTRATIL
|
K772
|
|
eNOS (rabbit)
|
VENLQSSKSTRATIL
|
K779
|
|
eNOS (pig)
|
VENLQSSKSTRATIL
|
K775
|
|
eNOS (sheep)
|
VENLQSSKSTRATIL
|
K778
|
|
eNOS (cow)
|
VENLQSSKSTRATIL
|
K775
|
|
|
K833
|
VAVEQLEKGSPGGPP
|
|
|
0
|
2
|
|
|
|
eNOS (human)
|
VAVEQLEkGsPGGPP
|
K834-ub
|
|
eNOS (mouse)
|
VAVEQLEKGSPGGPP
|
K833
|
|
eNOS (rat)
|
VAVEQLEKGSPGGPP
|
K833
|
|
eNOS (rabbit)
|
VAVEQLEKGSPGGPP
|
K840
|
|
eNOS (pig)
|
VAVEQLEKGSPGGPP
|
K836
|
|
eNOS (sheep)
|
gap
|
-
|
|
eNOS (cow)
|
VAVEQLEKGSPGGPP
|
K836
|
|
|
S835
|
VEQLEKGSPGGPPPG
|
|
|
0
|
1
|
|
|
|
eNOS (human)
|
VEQLEkGsPGGPPPG
|
S836-p
|
|
eNOS (mouse)
|
VEQLEKGSPGGPPPG
|
S835
|
|
eNOS (rat)
|
VEQLEKGSPGGPPPG
|
S835
|
|
eNOS (rabbit)
|
VEQLEKGSPGGPPPS
|
S842
|
|
eNOS (pig)
|
VEQLEKGSPGGPPPS
|
S838
|
|
eNOS (sheep)
|
gap
|
-
|
|
eNOS (cow)
|
VEQLEKGSPGGPPPS
|
S838
|
|
|
T853
|
DPRLPPCTLRQALTY
|
|
|
0
|
1
|
|
|
|
eNOS (human)
|
DPRLPPCtLRQALTF
|
T854-p
|
|
eNOS (mouse)
|
DPRLPPCTLRQALTY
|
T853
|
|
eNOS (rat)
|
DPRLPPCTLRQALTY
|
T853
|
|
eNOS (rabbit)
|
DPRLPPCSLRQALTF
|
S860
|
|
eNOS (pig)
|
DPRLPPCTLRQALTF
|
T856
|
|
eNOS (sheep)
|
DPRLPPCTLRQALTF
|
T855
|
|
eNOS (cow)
|
DPRLPPCTLRQALTF
|
T856
|
|
|
T865
|
LTYFLDITSPPSPRL
|
|
|
1
|
1
|
|
|
|
eNOS (human)
|
LTFFLDItsPPSPQL
|
T866-gl
|
|
eNOS (mouse)
|
LTYFLDITSPPSPRL
|
T865
|
|
eNOS (rat)
|
LTYFLDITSPPSPRL
|
T865
|
|
eNOS (rabbit)
|
LTFFLDITSPSSPRL
|
T872
|
|
eNOS (pig)
|
LTFFLDITSPPSPRL
|
T868
|
|
eNOS (sheep)
|
LTFFLDITSPPSPRL
|
T867
|
|
eNOS (cow)
|
LTFFLDItSPPSPRL
|
T868-gl
|
|
|
S866
|
TYFLDITSPPSPRLL
|
|
|
1
|
1
|
|
|
|
eNOS (human)
|
TFFLDItsPPSPQLL
|
S867-gl
|
|
eNOS (mouse)
|
TYFLDITSPPSPRLL
|
S866
|
|
eNOS (rat)
|
TYFLDITSPPSPRLL
|
S866
|
|
eNOS (rabbit)
|
TFFLDITSPSSPRLL
|
S873
|
|
eNOS (pig)
|
TFFLDITSPPSPRLL
|
S869
|
|
eNOS (sheep)
|
TFFLDITSPPSPRLL
|
S868
|
|
eNOS (cow)
|
TFFLDItSPPSPRLL
|
S869
|
|
|
K903
|
PRRYEEWKWFRCPTL
|
|
|
0
|
1
|
|
|
|
eNOS (human)
|
PRRYEEWkWFRCPTL
|
K904-ub
|
|
eNOS (mouse)
|
PRRYEEWKWFSCPTL
|
K903
|
|
eNOS (rat)
|
PRRYEEWKWFRCPTL
|
K903
|
|
eNOS (rabbit)
|
PRRYEEWKWFRCPTL
|
K910
|
|
eNOS (pig)
|
PRRYEEWKWFRCPTL
|
K906
|
|
eNOS (sheep)
|
PRRYEEWKWFRCPTL
|
K905
|
|
eNOS (cow)
|
PRRYEEWKWFRCPTL
|
K906
|
|
|
K1034
|
RLHDIEIKGLQPAPM
|
|
|
0
|
1
|
|
|
|
eNOS (human)
|
RLHDIESkGLQPTPM
|
K1035-ub
|
|
eNOS (mouse)
|
RLHDIEIKGLQPAPM
|
K1034
|
|
eNOS (rat)
|
RLHDIEIKGLQPAPM
|
K1034
|
|
eNOS (rabbit)
|
RLHDIESKGLQPAPL
|
K1041
|
|
eNOS (pig)
|
RLHDIESKGLQPAPM
|
K1037
|
|
eNOS (sheep)
|
RLHDIESKGLQRAAP
|
K1037
|
|
eNOS (cow)
|
RLHDIESKGLQPAPM
|
K1037
|
|
|
K1084-ac
|
SRDPGSPkTYVQDLL
|
|
|
0
|
1
|
|
|
|
eNOS (human)
|
SREPDNPKTYVQDIL
|
K1085
|
|
eNOS (mouse)
|
SRDPGSPKTYVQDLL
|
K1084
|
|
eNOS (rat)
|
SRDPGSPkTYVQDLL
|
K1084-ac
|
|
eNOS (rabbit)
|
SREPDSPKTYVQDIL
|
K1091
|
|
eNOS (pig)
|
SREPDSPKTYVQDIL
|
K1087
|
|
eNOS (sheep)
|
SREPDSPKTYVQDIL
|
K1087
|
|
eNOS (cow)
|
SREPDSPKTYVQDIL
|
K1087
|
|
|
K1084
|
SRDPGSPKTYVQDLL
|
|
|
0
|
3
|
|
|
|
eNOS (human)
|
SREPDNPkTYVQDIL
|
K1085-ub
|
|
eNOS (mouse)
|
SRDPGSPKTYVQDLL
|
K1084
|
|
eNOS (rat)
|
SRDPGSPKTYVQDLL
|
K1084
|
|
eNOS (rabbit)
|
SREPDSPKTYVQDIL
|
K1091
|
|
eNOS (pig)
|
SREPDSPKTYVQDIL
|
K1087
|
|
eNOS (sheep)
|
SREPDSPKTYVQDIL
|
K1087
|
|
eNOS (cow)
|
SREPDSPKTYVQDIL
|
K1087
|
|
|
T1093
|
YVQDLLRTELAAEVH
|
|
|
0
|
1
|
|
|
|
eNOS (human)
|
YVQDILRtELAAEVH
|
T1094-p
|
|
eNOS (mouse)
|
YVQDLLRTELAAEVH
|
T1093
|
|
eNOS (rat)
|
YVQDLLRTELAAEVH
|
T1093
|
|
eNOS (rabbit)
|
YVQDILRTELASEVH
|
T1100
|
|
eNOS (pig)
|
YVQDILRTELAAEVH
|
T1096
|
|
eNOS (sheep)
|
YVQDILRTELAAEVH
|
T1096
|
|
eNOS (cow)
|
YVQDILRTELAAEVH
|
T1096
|
|
|
T1174-p
|
EVTSRIRtQsFsLQE
|
|
|
2
|
19
|
|
|
|
eNOS (human)
|
EVTSRIRtQsFsLQE
|
T1175-p
|
|
eNOS (mouse)
|
EVTSRIRtQsFsLQE
|
T1174-p
|
|
eNOS (rat)
|
EVTSRIRtQsFsLQE
|
T1174-p
|
|
eNOS (rabbit)
|
EVTSRIRTQsFSLQE
|
T1181
|
|
eNOS (pig)
|
EVTSRIRtQsFSLQE
|
T1177-p
|
|
eNOS (sheep)
|
EVTSRIRTQSFSLQE
|
T1177
|
|
eNOS (cow)
|
EVTSRIRtQsFsLQE
|
T1177-p
|
|
|
S1176-p
|
TSRIRtQsFsLQERQ
|
Upstream
|
Downstream
|
241
|
26
|
|
|
|
|
|
Effects on Modified Protein
- activity, induced
- enzymatic activity, induced
|
|
Effects on Biological Processes:
- signaling pathway regulation
|
|
|
Kinase, in vitro:
- AMPKA1 (rat)
- PKACA (human)
|
|
Putative in vivo kinases:
- Akt1 (human)
- Akt1 (rat)
- AMPKA1 (rat)
|
|
Putative upstream phosphatases:
|
|
Regulatory protein:
- CYBA (human)
- GIT1 (rat)
- GRK2 (rat)
|
|
Treatment
- extracellular vesicles
- acadesine
- ACh
- Angelica gigas NAKAI extract
- angiotensin_2
- antimiR-199a
- apocynin
- atorvastatin
- beta-amyloid_40
- bisperoxovanadium
- bradykinin
- butyrate
- caffeine
- cAMP_analog
- candesartan
- compound_C
- decursin
- deoxygenation
- endothelin
- exercise
- fluid_shear_stress
- fructose-rich diet
- gadolinium
- GKT137831
- glucose_starvation
- Go_6976
- H-89
- high-fat diet
- high-salt diet
- hyperglycemia
- hyperoxia
- hypertension
- hypoxia
- insulin
- ischemia
- ischemia/reperfusion
- L-NAME
- LDL_oxidized
- leptin
- low_Ca(2+)
- LY294002
- MCTP
- myricetin
- NAC
- niclosamide
- obesity
- okadaic_acid
- PP2
- PTX
- quercetin
- ROC-325
- Safflor yellow B
- simvastatin
- streptozotocin
- tautomycin
- U0126
- wortmannin
- Yoda1
|
|
|
eNOS (human)
|
TSRIRtQsFsLQERQ
|
S1177-p
|
|
eNOS (mouse)
|
TSRIRtQsFsLQERQ
|
S1176-p
|
|
eNOS (rat)
|
TSRIRtQsFsLQERQ
|
S1176-p
|
|
eNOS (rabbit)
|
TSRIRTQsFSLQERQ
|
S1183-p
|
|
eNOS (pig)
|
TSRIRtQsFSLQERH
|
S1179-p
|
|
eNOS (sheep)
|
TSRIRTQSFSLQERH
|
S1179
|
|
eNOS (cow)
|
TSRIRtQsFsLQERH
|
S1179-p
|
|
|
S1176-gl
|
TSRIRtQsFsLQERQ
|
|
|
2
|
0
|
|
|
|
eNOS (human)
|
TSRIRtQsFsLQERQ
|
S1177-gl
|
|
eNOS (mouse)
|
TSRIRtQSFsLQERQ
|
S1176
|
|
eNOS (rat)
|
TSRIRtQsFsLQERQ
|
S1176-gl
|
|
eNOS (rabbit)
|
TSRIRTQSFSLQERQ
|
S1183
|
|
eNOS (pig)
|
TSRIRtQSFSLQERH
|
S1179
|
|
eNOS (sheep)
|
TSRIRTQSFSLQERH
|
S1179
|
|
eNOS (cow)
|
TSRIRtQSFsLQERH
|
S1179
|
|
|
S1178-p
|
RIRtQsFsLQERQLR
|
Upstream
|
Downstream
|
11
|
9
|
|
|
|
Effects on Modified Protein
- enzymatic activity, induced
|
|
|
Treatment
- Akt-I-1
- estradiol
- H-89
- insulin
- ischemia/reperfusion
- spironolactone
- U0126
- wortmannin
|
|
|
eNOS (human)
|
RIRtQsFsLQERQLR
|
S1179-p
|
|
eNOS (mouse)
|
RIRtQsFsLQERQLR
|
S1178-p
|
|
eNOS (rat)
|
RIRtQsFsLQERQLR
|
S1178-p
|
|
eNOS (rabbit)
|
RIRTQsFSLQERQLR
|
S1185
|
|
eNOS (pig)
|
RIRtQsFSLQERHLR
|
S1181
|
|
eNOS (sheep)
|
RIRTQSFSLQERHLR
|
S1181
|
|
eNOS (cow)
|
RIRtQsFsLQERHLR
|
S1181-p
|
|
