Other Species / Isoforms
  SREBP-2 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
S79-p
SSSNGRGsssGAVDP
0 1
SREBP-2 (human) SSSNGRGsssGAVDP S79-p
SREBP-2 (mouse) NNSSGRGNNGGATDP N72
S80-p
SSNGRGsssGAVDPS
0 1
SREBP-2 (human) SSNGRGsssGAVDPS S80-p
SREBP-2 (mouse) NSSGRGNNGGATDPA N73
S81-p
SNGRGsssGAVDPSV
0 1
SREBP-2 (human) SNGRGsssGAVDPSV S81-p
SREBP-2 (mouse) SSGRGNNGGATDPAV G74
S101-p
QVTLPSFsPSAAsPQ
0 2
SREBP-2 (human) QVTLPSFsPSAAsPQ S101-p
SREBP-2 (mouse) QVPLSTFSPSAASPQ S94
S106-p
SFsPSAAsPQAPTLQ
0 1
SREBP-2 (human) SFsPSAAsPQAPTLQ S106-p
SREBP-2 (mouse) TFSPSAASPQAPALQ S99
K115-ub
QAPTLQVkVsPTsVP
0 1
SREBP-2 (human) QAPTLQVkVsPTsVP K115-ub
SREBP-2 (mouse) QAPALQVKVSPTPPR K108
S117-p
PTLQVkVsPTsVPTt
0 4
SREBP-2 (human) PTLQVkVsPTsVPTt S117-p
SREBP-2 (mouse) PALQVKVSPTPPRAT S110
S120-p
QVkVsPTsVPTtPRA
0 3
SREBP-2 (human) QVkVsPTsVPTtPRA S120-p
SREBP-2 (mouse) gap -
T124-p
sPTsVPTtPRATPIL
0 5
SREBP-2 (human) sPTsVPTtPRATPIL T124-p
SREBP-2 (mouse) QVKVSPTPPRATPVL P113
T153-p
QQQTVMItPtFSTTP
0 4
SREBP-2 (human) QQQTVMItPtFSTTP T153-p
SREBP-2 (mouse) QQQTVMITPTFSTAP T142
T155-p
QTVMItPtFSTTPQT
0 1
SREBP-2 (human) QTVMItPtFSTTPQT T155-p
SREBP-2 (mouse) QTVMITPTFSTAPQT T144
Y171-p
IIQQPLIyQNAATSF
0 1
SREBP-2 (human) IIQQPLIyQNAATSF Y171-p
SREBP-2 (mouse) IIQQPLIYQNAATSF Y160
K249-sm
LVQPQIIkTDsLVLT
0 1
SREBP-2 (human) LVQPQIIkTDsLVLT K249-sm
SREBP-2 (mouse) LVQPQIIKTDSLVLT K238
S252-p
PQIIkTDsLVLTTLK
0 1
SREBP-2 (human) PQIIkTDsLVLTTLK S252-p
SREBP-2 (mouse) PQIIKTDSLVLTTLK S241
K314-ub
GQEKVPIkQVPGGVk
0 3
SREBP-2 (human) GQEKVPIkQVPGGVk K314-ub
SREBP-2 (mouse) GQEKVPIKQVPGGVK K303
K321-ac
kQVPGGVkQLEPPKE
0 1
SREBP-2 (human) kQVPGGVkQLEPPKE K321-ac
SREBP-2 (mouse) KQVPGGVKQLDPPKE K310
T334
KEGERRTTHNIIEkR
0 1
SREBP-2 (human) KEGERRTTHNIIEkR T334
SREBP-2 (mouse) KEGERRTtHNIIEKR T323-p
K340-ub
TTHNIIEkRYRSSIN
0 3
SREBP-2 (human) TTHNIIEkRYRSSIN K340-ub
SREBP-2 (mouse) TtHNIIEKRYRSSIN K329
K354-ub
NDKIIELkDLVMGTD
0 2
SREBP-2 (human) NDKIIELkDLVMGTD K354-ub
SREBP-2 (mouse) NDKIIELKDLVMGTD K343
K363-ac
LVMGTDAkMHkSGVL
0 1
SREBP-2 (human) LVMGTDAkMHkSGVL K363-ac
SREBP-2 (mouse) LVMGTDAKMHKSGVL K352
K363-ub
LVMGTDAkMHkSGVL
0 2
SREBP-2 (human) LVMGTDAkMHkSGVL K363-ub
SREBP-2 (mouse) LVMGTDAKMHKSGVL K352
K366-ub
GTDAkMHkSGVLRkA
0 1
SREBP-2 (human) GTDAkMHkSGVLRkA K366-ub
SREBP-2 (mouse) GTDAKMHKSGVLRKA K355
K372-ub
HkSGVLRkAIDYIkY
0 2
SREBP-2 (human) HkSGVLRkAIDYIkY K372-ub
SREBP-2 (mouse) HKSGVLRKAIDYIKY K361
K378-ub
RkAIDYIkYLQQVNH
0 1
SREBP-2 (human) RkAIDYIkYLQQVNH K378-ub
SREBP-2 (mouse) RKAIDYIKYLQQVNH K367
K386-ub
YLQQVNHkLRQENMV
0 2
SREBP-2 (human) YLQQVNHkLRQENMV K386-ub
SREBP-2 (mouse) YLQQVNHKLRQENMV K375
K395-ub
RQENMVLkLANQkNK
0 1
SREBP-2 (human) RQENMVLkLANQkNK K395-ub
SREBP-2 (mouse) RQENMVLKLANQKNK K384
K400-ub
VLkLANQkNKLLkGI
0 1
SREBP-2 (human) VLkLANQkNKLLkGI K400-ub
SREBP-2 (mouse) VLKLANQKNKLLKGI K389
K405-ub
NQkNKLLkGIDLGSL
0 3
SREBP-2 (human) NQkNKLLkGIDLGSL K405-ub
SREBP-2 (mouse) NQKNKLLKGIDLGSL K394
S432-p
NQNVLLMsPPASDSG
Upstream
Downstream
1 0
Effects on Biological Processes:
  • transcription, induced
Kinase, in vitro:
  • ERK1 (human)
  • ERK2 (human)
Putative in vivo kinases:
  • ERK1 (human)
  • ERK2 (human)
Treatment
  • insulin
SREBP-2 (human) NQNVLLMsPPASDSG S432-p
SREBP-2 (mouse) NQNVLLMSPPASDSG S421
S455-p
SIDSEPGsPLLDDAK
Upstream
Downstream
2 0
Effects on Modified Protein
  • sumoylation
Effects on Biological Processes:
  • transcription, induced
Kinase, in vitro:
  • ERK1 (human)
  • ERK2 (human)
Putative in vivo kinases:
  • ERK1 (human)
  • ERK2 (human)
Treatment
  • insulin
SREBP-2 (human) SIDSEPGsPLLDDAK S455-p
SREBP-2 (mouse) SIDSEPGSPLLDDAK S444
K464-sm
LLDDAKVkDEPDsPP
2 0
SREBP-2 (human) LLDDAKVkDEPDsPP K464-sm
SREBP-2 (mouse) LLDDAKVKDEPDSPP K453
S469-p
KVkDEPDsPPVALGM
Upstream
0 7
Treatment
  • vemurafenib
SREBP-2 (human) KVkDEPDsPPVALGM S469-p
SREBP-2 (mouse) KVKDEPDSPPVALGM S458
K579-ub
VTFWRHRkQADLDLA
0 25
SREBP-2 (human) VTFWRHRkQADLDLA K579-ub
SREBP-2 (mouse) VTFWRHRKQADLDLA K568
K630-ac
VIRYSLQkLRLVRWL
0 1
SREBP-2 (human) VIRYSLQkLRLVRWL K630-ac
SREBP-2 (mouse) VIRYSLQKLRLVRWL K619
K640-ub
LVRWLLKkVFQCRRA
0 1
SREBP-2 (human) LVRWLLKkVFQCRRA K640-ub
SREBP-2 (mouse) LVRWLLKKVFQRWRA K629
K660-ub
AGFEDEAkTSARDAA
0 3
SREBP-2 (human) AGFEDEAkTSARDAA K660-ub
SREBP-2 (mouse) AGFEDEAKSSARDAA K649
K731-ub
LKTRCGGkLGFLASY
0 1
SREBP-2 (human) LKTRCGGkLGFLASY K731-ub
SREBP-2 (mouse) LKTRCGGKLGFLASY K720
S745-p
YFLSRAQsLCGPEHS
0 1
SREBP-2 (human) YFLSRAQsLCGPEHS S745-p
SREBP-2 (mouse) YFLNRAQSLCGPEHS S734
K768-ub
LCHPLGQkFFMERSW
0 1
SREBP-2 (human) LCHPLGQkFFMERSW K768-ub
SREBP-2 (mouse) LCHPLGQKFFMERSW K757
K778-ub
MERSWSVkSAAkESL
0 2
SREBP-2 (human) MERSWSVkSAAkESL K778-ub
SREBP-2 (mouse) MERSWSIKSAAKESL K767
K782-ub
WSVkSAAkESLYCAQ
0 2
SREBP-2 (human) WSVkSAAkESLYCAQ K782-ub
SREBP-2 (mouse) WSIKSAAKESLYCAQ K771
N791
SLYCAQRNPADPIAQ
0 1
SREBP-2 (human) SLYCAQRNPADPIAQ N791
SREBP-2 (mouse) SLYCAQRsPADPIAQ S780-p
K805-ub
QVHQAFCkNLLERAI
0 2
SREBP-2 (human) QVHQAFCkNLLERAI K805-ub
SREBP-2 (mouse) QVHQAFCKNLLERAV K794
K817-ub
RAIESLVkPQAkKkA
0 3
SREBP-2 (human) RAIESLVkPQAkKkA K817-ub
SREBP-2 (mouse) RAVESLVKPQAKKKA K806
K821-ub
SLVkPQAkKkAGDQE
0 1
SREBP-2 (human) SLVkPQAkKkAGDQE K821-ub
SREBP-2 (mouse) SLVKPQAKKKAGDQE K810
K823-ub
VkPQAkKkAGDQEEE
0 1
SREBP-2 (human) VkPQAkKkAGDQEEE K823-ub
SREBP-2 (mouse) VKPQAKKKAGDQEEE K812
Y840-p
EFSSALEyLKLLHSF
0 1
SREBP-2 (human) EFSSALEyLKLLHSF Y840-p
SREBP-2 (mouse) EFSSALEYLKLLHSF Y829
S855-p
VDSVGVMsPPLSRSS
0 2
SREBP-2 (human) VDSVGVMsPPLSRSS S855-p
SREBP-2 (mouse) VDSVGFVTSPFSSSS T844
K865-ub
LSRSSVLkSALGPDI
0 1
SREBP-2 (human) LSRSSVLkSALGPDI K865-ub
SREBP-2 (mouse) FSSSSVLRSALGPDV R854
K901-ub
AVRSHFTkVERIPkA
0 1
SREBP-2 (human) AVRSHFTkVERIPkA K901-ub
SREBP-2 (mouse) AVRSRFTEVERVPKA E890
K907-ub
TkVERIPkALEVTES
0 3
SREBP-2 (human) TkVERIPkALEVTES K907-ub
SREBP-2 (mouse) TEVERVPKALEVTEs K896
S914
kALEVTESPLVkAIF
0 1
SREBP-2 (human) kALEVTESPLVkAIF S914
SREBP-2 (mouse) KALEVTEsPLVKAVF S903-p
K918-ub
VTESPLVkAIFHACR
0 1
SREBP-2 (human) VTESPLVkAIFHACR K918-ub
SREBP-2 (mouse) VTEsPLVKAVFYTCR K907
K934-ub
MHASLPGkADGQQSS
0 2
SREBP-2 (human) MHASLPGkADGQQSS K934-ub
SREBP-2 (mouse) MHASLSGKADGQQNS K923
K989-ub
LRTALWQkQASASQA
0 1
SREBP-2 (human) LRTALWQkQASASQA K989-ub
SREBP-2 (mouse) LRTALWQKQASASQL K978
K1031-ub
SFRPAYRkVFLHEAT
0 2
SREBP-2 (human) SFRPAYRkVFLHEAT K1031-ub
SREBP-2 (mouse) SFRPAYRKVFLHEAT K1020
S1057-p
THQLLEHsLRRRTTQ
0 1
SREBP-2 (human) THQLLEHsLRRRTTQ S1057-p
SREBP-2 (mouse) THQLLEHSLRRRPTQ S1046
K1067-ub
RRTTQSTkHGEVDAW
0 2
SREBP-2 (human) RRTTQSTkHGEVDAW K1067-ub
SREBP-2 (mouse) RRPTQNTKHGEVDTW K1056
S1094-p
ACRHLPLsFLSsPGQ
0 1
SREBP-2 (human) ACRHLPLsFLSsPGQ S1094-p
SREBP-2 (mouse) ACRHLPLSFLSSPGQ S1083
S1098-p
LPLsFLSsPGQRAVL
0 1
SREBP-2 (human) LPLsFLSsPGQRAVL S1098-p
SREBP-2 (mouse) LPLSFLSSPGQRAVL S1087
K1115-ub
EAARTLEkVGDRRsC
0 3
SREBP-2 (human) EAARTLEkVGDRRsC K1115-ub
SREBP-2 (mouse) EAARTLEKVGDRRSC K1104
S1121-p
EkVGDRRsCNDCQQM
0 1
SREBP-2 (human) EkVGDRRsCNDCQQM S1121-p
SREBP-2 (mouse) EKVGDRRSCSDCQQM S1110