S7-p
|
_MTAMEEsQsDIsLE
|
Upstream
|
|
6
|
0
|
|
|
Kinase, in vitro:
- CK1A (human)
- CK1D (human)
- CK1E (human)
- DNAPK (human)
|
Putative in vivo kinases:
- CK1D (human)
- CK1E (human)
|
Treatment
|
|
p53 (human)
|
____MEEPQsDPsVE
|
P4
|
p53 iso2 (human)
|
____MEEPQSDPSVE
|
P4
|
p53 iso4 (human)
|
gap
|
-
|
p53 (mouse)
|
_MTAMEEsQsDIsLE
|
S7-p
|
p53 iso2 (mouse)
|
_MTAMEESQSDISLE
|
S7
|
p53 (rat)
|
____MEDsQsDMsIE
|
S4-p
|
p53 (rabbit)
|
____MEESQSDLSLE
|
S4
|
p53 (green monkey)
|
____MEEPQSDPSIE
|
P4
|
|
S9-p
|
TAMEEsQsDIsLELP
|
Upstream
|
|
35
|
3
|
|
|
|
Kinase, in vitro:
- CK1A (human)
- CK1D (human)
- CK1E (human)
|
Putative in vivo kinases:
- CK1D (human)
- CK1E (human)
|
Treatment
|
|
p53 (human)
|
__MEEPQsDPsVEPP
|
S6-p
|
p53 iso2 (human)
|
__MEEPQSDPSVEPP
|
S6
|
p53 iso4 (human)
|
gap
|
-
|
p53 (mouse)
|
TAMEEsQsDIsLELP
|
S9-p
|
p53 iso2 (mouse)
|
TAMEESQSDISLELP
|
S9
|
p53 (rat)
|
__MEDsQsDMsIELP
|
S6-p
|
p53 (rabbit)
|
__MEESQSDLSLEPP
|
S6
|
p53 (green monkey)
|
__MEEPQSDPSIEPP
|
S6
|
|
S12-p
|
EEsQsDIsLELPLsQ
|
Upstream
|
|
40
|
4
|
|
|
|
Kinase, in vitro:
- CK1A (human)
- CK1D (human)
- CK1E (human)
|
Putative in vivo kinases:
- CK1D (human)
- CK1E (human)
|
Treatment
|
|
p53 (human)
|
EEPQsDPsVEPPLsQ
|
S9-p
|
p53 iso2 (human)
|
EEPQSDPSVEPPLSQ
|
S9
|
p53 iso4 (human)
|
gap
|
-
|
p53 (mouse)
|
EEsQsDIsLELPLsQ
|
S12-p
|
p53 iso2 (mouse)
|
EESQSDISLELPLsQ
|
S12
|
p53 (rat)
|
EDsQsDMsIELPLsQ
|
S9-p
|
p53 (rabbit)
|
EESQSDLSLEPPLSQ
|
S9
|
p53 (green monkey)
|
EEPQSDPSIEPPLsQ
|
S9
|
|
S18-p
|
IsLELPLsQEtFsGL
|
Upstream
|
Downstream
|
481
|
12
|
|
|
|
Effects on Modified Protein
- activity, induced
- intracellular localization
- molecular association, regulation
- phosphorylation
- protein conformation
- protein stabilization
|
Effects on Biological Processes:
- DNA repair, induced
- apoptosis, altered
- apoptosis, induced
- apoptosis, inhibited
- carcinogenesis, induced
- carcinogenesis, inhibited
- cell cycle regulation
- cell growth, altered
- cell growth, inhibited
- transcription, altered
- transcription, induced
- transcription, inhibited
|
|
|
p53 (human)
|
PsVEPPLsQEtFsDL
|
S15-p
|
p53 iso2 (human)
|
PSVEPPLSQETFSDL
|
S15
|
p53 iso4 (human)
|
gap
|
-
|
p53 (mouse)
|
IsLELPLsQEtFsGL
|
S18-p
|
p53 iso2 (mouse)
|
ISLELPLsQETFSGL
|
S18-p
|
p53 (rat)
|
MsIELPLsQEtFsCL
|
S15-p
|
p53 (rabbit)
|
LSLEPPLSQETFSDL
|
S15
|
p53 (green monkey)
|
PSIEPPLsQETFSDL
|
S15-p
|
|
T21-p
|
ELPLsQEtFsGLWKL
|
Upstream
|
Downstream
|
34
|
0
|
|
|
|
Effects on Modified Protein
- activity, induced
- intracellular localization
- molecular association, regulation
- protein stabilization
|
Effects on Biological Processes:
- apoptosis, altered
- cell cycle regulation
- transcription, altered
|
|
Kinase, in vitro:
- VRK1 (human)
- VRK2 (human)
- VRK2 iso2 (human)
|
Putative in vivo kinases:
- CK1A (human)
- VRK2 iso2 (human)
|
Regulatory protein:
- PIK3R1 (mouse)
- PML (human)
|
Treatment
- adriamycin
- MG132
- taxol
- UVB
|
|
p53 (human)
|
EPPLsQEtFsDLWkL
|
T18-p
|
p53 iso2 (human)
|
EPPLSQETFSDLWKL
|
T18
|
p53 iso4 (human)
|
gap
|
-
|
p53 (mouse)
|
ELPLsQEtFsGLWKL
|
T21-p
|
p53 iso2 (mouse)
|
ELPLsQETFSGLWKL
|
T21
|
p53 (rat)
|
ELPLsQEtFsCLWKL
|
T18-p
|
p53 (rabbit)
|
EPPLSQETFSDLWKL
|
T18
|
p53 (green monkey)
|
EPPLsQETFSDLWKL
|
T18
|
|
S23-p
|
PLsQEtFsGLWKLLP
|
Upstream
|
Downstream
|
127
|
2
|
|
|
|
Effects on Modified Protein
- activity, induced
- molecular association, regulation
- protein stabilization
|
Effects on Biological Processes:
- apoptosis, altered
- cell cycle regulation
- cell growth, altered
- transcription, inhibited
|
|
Regulatory protein:
- ATR (human)
- BRCA1 (mouse)
- HBpX (retrovirus)
- P38A (human)
- PIK3R1 (mouse)
|
Treatment
- adriamycin
- etoposide
- ionizing_radiation
- LLnL
- UV
- UVB
|
|
p53 (human)
|
PLsQEtFsDLWkLLP
|
S20-p
|
p53 iso2 (human)
|
PLSQETFSDLWKLLP
|
S20
|
p53 iso4 (human)
|
gap
|
-
|
p53 (mouse)
|
PLsQEtFsGLWKLLP
|
S23-p
|
p53 iso2 (mouse)
|
PLsQETFSGLWKLLP
|
S23
|
p53 (rat)
|
PLsQEtFsCLWKLLP
|
S20-p
|
p53 (rabbit)
|
PLSQETFSDLWKLLP
|
S20
|
p53 (green monkey)
|
PLsQETFSDLWKLLP
|
S20
|
|
K27
|
EtFsGLWKLLPPEDI
|
|
|
1
|
0
|
|
|
p53 (human)
|
EtFsDLWkLLPENNV
|
K24-ub
|
p53 iso2 (human)
|
ETFSDLWKLLPENNV
|
K24
|
p53 iso4 (human)
|
gap
|
-
|
p53 (mouse)
|
EtFsGLWKLLPPEDI
|
K27
|
p53 iso2 (mouse)
|
ETFSGLWKLLPPEDI
|
K27
|
p53 (rat)
|
EtFsCLWKLLPPDDI
|
K24
|
p53 (rabbit)
|
ETFSDLWKLLPENNL
|
K24
|
p53 (green monkey)
|
ETFSDLWKLLPENNV
|
K24
|
|
-
|
gap
|
|
|
34
|
3
|
|
|
|
|
S37-p
|
PPEDILPsPHCMDDL
|
Upstream
|
Downstream
|
4
|
1
|
|
|
Effects on Modified Protein
|
|
|
p53 (human)
|
ENNVLsPLPsQAMDD
|
L35
|
p53 iso2 (human)
|
ENNVLSPLPSQAMDD
|
L35
|
p53 iso4 (human)
|
gap
|
-
|
p53 (mouse)
|
PPEDILPsPHCMDDL
|
S37-p
|
p53 iso2 (mouse)
|
PPEDILPSPHCMDDL
|
S37
|
p53 (rat)
|
PDDILPTTATGsPNS
|
T35
|
p53 (rabbit)
|
LPENNLLTTSLNPPV
|
T33
|
p53 (green monkey)
|
ENNVLsPLPSQAVDD
|
L35
|
|
-
|
gap
|
|
|
66
|
2
|
|
|
|
p53 (human)
|
NVLsPLPsQAMDDLM
|
S37-p
|
p53 iso2 (human)
|
NVLSPLPSQAMDDLM
|
S37
|
p53 iso4 (human)
|
gap
|
-
|
p53 (mouse)
|
gap
|
-
|
p53 iso2 (mouse)
|
gap
|
-
|
p53 (rat)
|
DILPTTATGsPNSME
|
T37
|
p53 (rabbit)
|
ENNLLTTSLNPPVDD
|
S35
|
p53 (green monkey)
|
NVLsPLPSQAVDDLM
|
S37
|
|
-
|
gap
|
|
|
1
|
0
|
|
|
|
-
|
gap
|
|
|
115
|
3
|
|
|
|
|
E55
|
QDVEEFFEGPsEALR
|
|
|
23
|
0
|
|
|
p53 (human)
|
DDIEQWFtEDPGPDE
|
T55-p
|
p53 iso2 (human)
|
DDIEQWFTEDPGPDE
|
T55
|
p53 iso4 (human)
|
DDIEQWFTEDPGPDE
|
T16
|
p53 (mouse)
|
QDVEEFFEGPsEALR
|
E55
|
p53 iso2 (mouse)
|
QDVEEFFEGPSEALR
|
E55
|
p53 (rat)
|
QDVAELLEGPEEALQ
|
E57
|
p53 (rabbit)
|
EDVANWLNEDPEEGL
|
N54
|
p53 (green monkey)
|
DDLAQWLTEDPGPDE
|
T55
|
|
S58-p
|
EEFFEGPsEALRVSG
|
Upstream
|
Downstream
|
2
|
0
|
|
|
Effects on Biological Processes:
- apoptosis, inhibited
- transcription, induced
|
|
Putative in vivo kinases:
|
Treatment
|
|
p53 (human)
|
FtEDPGPDEAPRMPE
|
D61
|
p53 iso2 (human)
|
FTEDPGPDEAPRMPE
|
D61
|
p53 iso4 (human)
|
FTEDPGPDEAPRMPE
|
D22
|
p53 (mouse)
|
EEFFEGPsEALRVSG
|
S58-p
|
p53 iso2 (mouse)
|
EEFFEGPSEALRVSG
|
S58
|
p53 (rat)
|
AELLEGPEEALQVSA
|
E60
|
p53 (rabbit)
|
NWLNEDPEEGLRVPA
|
E58
|
p53 (green monkey)
|
LTEDPGPDEAPRMSE
|
D61
|
|
G78
|
DPVTETPGPVAPAPA
|
|
|
11
|
2
|
|
|
|
p53 (human)
|
APAPAAPtPAAPAPA
|
T81-p
|
p53 iso2 (human)
|
APAPAAPTPAAPAPA
|
T81
|
p53 iso4 (human)
|
APAPAAPTPAAPAPA
|
T42
|
p53 (mouse)
|
DPVTETPGPVAPAPA
|
G78
|
p53 iso2 (mouse)
|
DPVTETPGPVAPAPA
|
G78
|
p53 (rat)
|
EPGTEAPAPVAPASA
|
A79
|
p53 (rabbit)
|
APAPAAPALAAPAPA
|
A78
|
p53 (green monkey)
|
APTPAAPTPAAPAPA
|
T81
|
|
S96
|
PLSSFVPSQkTYQGN
|
|
|
0
|
2
|
|
|
p53 (human)
|
PLSSSVPsQkTYQGs
|
S99-p
|
p53 iso2 (human)
|
PLSSSVPSQKTYQGS
|
S99
|
p53 iso4 (human)
|
PLSSSVPSQKTYQGS
|
S60
|
p53 (mouse)
|
PLSSFVPSQkTYQGN
|
S96
|
p53 iso2 (mouse)
|
PLSSFVPSQkTYQGN
|
S96
|
p53 (rat)
|
PLSSSVPSQKTYQGN
|
S97
|
p53 (rabbit)
|
PLSSSVPSQKTYHGN
|
S96
|
p53 (green monkey)
|
PLSSSVPSQKTYHGS
|
S99
|
|
K98-ac
|
SSFVPSQkTYQGNYG
|
|
Downstream
|
2
|
1
|
|
|
Effects on Biological Processes:
- apoptosis, induced
- carcinogenesis, inhibited
- cell cycle regulation
|
|
p53 (human)
|
SSSVPsQKTYQGsYG
|
K101
|
p53 iso2 (human)
|
SSSVPSQKTYQGSYG
|
K101
|
p53 iso4 (human)
|
SSSVPSQKTYQGSYG
|
K62
|
p53 (mouse)
|
SSFVPSQkTYQGNYG
|
K98-ac
|
p53 iso2 (mouse)
|
SSFVPSQkTYQGNYG
|
K98-ac
|
p53 (rat)
|
SSSVPSQKTYQGNYG
|
K99
|
p53 (rabbit)
|
SSSVPSQKTYHGNYG
|
K98
|
p53 (green monkey)
|
SSSVPSQKTYHGSYG
|
K101
|
|
K98
|
SSFVPSQKTYQGNYG
|
|
|
1
|
3
|
|
|
p53 (human)
|
SSSVPsQkTYQGsYG
|
K101-ub
|
p53 iso2 (human)
|
SSSVPSQKTYQGSYG
|
K101
|
p53 iso4 (human)
|
SSSVPSQKTYQGSYG
|
K62
|
p53 (mouse)
|
SSFVPSQKTYQGNYG
|
K98
|
p53 iso2 (mouse)
|
SSFVPSQKTYQGNYG
|
K98
|
p53 (rat)
|
SSSVPSQKTYQGNYG
|
K99
|
p53 (rabbit)
|
SSSVPSQKTYHGNYG
|
K98
|
p53 (green monkey)
|
SSSVPSQKTYHGSYG
|
K101
|
|
N103
|
SQkTYQGNYGFHLGF
|
|
|
1
|
1
|
|
|
p53 (human)
|
sQkTYQGsYGFrLGF
|
S106-p
|
p53 iso2 (human)
|
SQKTYQGSYGFRLGF
|
S106
|
p53 iso4 (human)
|
SQKTYQGSYGFRLGF
|
S67
|
p53 (mouse)
|
SQkTYQGNYGFHLGF
|
N103
|
p53 iso2 (mouse)
|
SQkTYQGNYGFHLGF
|
N103
|
p53 (rat)
|
SQKTYQGNYGFHLGF
|
N104
|
p53 (rabbit)
|
SQKTYHGNYGFRLGF
|
N103
|
p53 (green monkey)
|
SQKTYHGSYGFRLGF
|
S106
|
|
H107
|
YQGNYGFHLGFLQSG
|
|
|
0
|
1
|
|
|
p53 (human)
|
YQGsYGFrLGFLhSG
|
R110-m1
|
p53 iso2 (human)
|
YQGSYGFRLGFLHSG
|
R110
|
p53 iso4 (human)
|
YQGSYGFRLGFLHSG
|
R71
|
p53 (mouse)
|
YQGNYGFHLGFLQSG
|
H107
|
p53 iso2 (mouse)
|
YQGNYGFHLGFLQSG
|
H107
|
p53 (rat)
|
YQGNYGFHLGFLQSG
|
H108
|
p53 (rabbit)
|
YHGNYGFRLGFLHSG
|
R107
|
p53 (green monkey)
|
YHGSYGFRLGFLHSG
|
R110
|
|
Q112
|
GFHLGFLQSGTAkSV
|
|
|
0
|
1
|
|
|
p53 (human)
|
GFrLGFLhSGTAkSV
|
H115-m1
|
p53 iso2 (human)
|
GFRLGFLHSGTAKSV
|
H115
|
p53 iso4 (human)
|
GFRLGFLHSGTAKSV
|
H76
|
p53 (mouse)
|
GFHLGFLQSGTAkSV
|
Q112
|
p53 iso2 (mouse)
|
GFHLGFLQSGTAkSV
|
Q112
|
p53 (rat)
|
GFHLGFLQSGTAkSV
|
Q113
|
p53 (rabbit)
|
GFRLGFLHSGTAKSV
|
H112
|
p53 (green monkey)
|
GFRLGFLHSGTAKSV
|
H115
|
|
K117-ac
|
FLQSGTAkSVMCTYS
|
Upstream
|
Downstream
|
45
|
8
|
|
|
Effects on Biological Processes:
- apoptosis, induced
- carcinogenesis, inhibited
- cell cycle regulation
- cell growth, inhibited
- transcription, induced
|
|
Regulatory protein:
- GFI1 (mouse)
- HDAC6 (human)
- HDAC6 (mouse)
- SETD7 (mouse)
|
Treatment
- CHIR99021
- DEN
- hepatectomy
- high-fat diet
- thioacetamide
|
|
p53 (human)
|
FLhSGTAkSVTCTyS
|
K120-ac
|
p53 iso2 (human)
|
FLHSGTAKSVTCTYS
|
K120
|
p53 iso4 (human)
|
FLHSGTAKSVTCTYS
|
K81
|
p53 (mouse)
|
FLQSGTAkSVMCTYS
|
K117-ac
|
p53 iso2 (mouse)
|
FLQSGTAkSVMCTYS
|
K117-ac
|
p53 (rat)
|
FLQSGTAkSVMCTYS
|
K118-ac
|
p53 (rabbit)
|
FLHSGTAKSVTCTYS
|
K117
|
p53 (green monkey)
|
FLHSGTAKSVTCTYS
|
K120
|
|
K117
|
FLQSGTAKSVMCTYS
|
|
|
1
|
21
|
|
|
p53 (human)
|
FLhSGTAkSVTCTyS
|
K120-ub
|
p53 iso2 (human)
|
FLHSGTAKSVTCTYS
|
K120
|
p53 iso4 (human)
|
FLHSGTAKSVTCTYS
|
K81
|
p53 (mouse)
|
FLQSGTAKSVMCTYS
|
K117
|
p53 iso2 (mouse)
|
FLQSGTAKSVMCTYS
|
K117
|
p53 (rat)
|
FLQSGTAKSVMCTYS
|
K118
|
p53 (rabbit)
|
FLHSGTAKSVTCTYS
|
K117
|
p53 (green monkey)
|
FLHSGTAKSVTCTYS
|
K120
|
|
Y123
|
AkSVMCTYSPPLNKL
|
|
|
1
|
0
|
|
|
p53 (human)
|
AkSVTCTySPALNkM
|
Y126-p
|
p53 iso2 (human)
|
AKSVTCTYSPALNKM
|
Y126
|
p53 iso4 (human)
|
AKSVTCTYSPALNKM
|
Y87
|
p53 (mouse)
|
AkSVMCTYSPPLNKL
|
Y123
|
p53 iso2 (mouse)
|
AkSVMCTYSPPLNKL
|
Y123
|
p53 (rat)
|
AkSVMCTYSISLNKL
|
Y124
|
p53 (rabbit)
|
AKSVTCTYSPCLNKL
|
Y123
|
p53 (green monkey)
|
AKSVTCTYSPDLNKM
|
Y126
|
|
K129
|
TYSPPLNKLFCQLAk
|
|
|
2
|
2
|
|
|
p53 (human)
|
TySPALNkMFCQLAk
|
K132-ub
|
p53 iso2 (human)
|
TYSPALNKMFCQLAK
|
K132
|
p53 iso4 (human)
|
TYSPALNKMFCQLAK
|
K93
|
p53 (mouse)
|
TYSPPLNKLFCQLAk
|
K129
|
p53 iso2 (mouse)
|
TYSPPLNKLFCQLAK
|
K129
|
p53 (rat)
|
TYSISLNKLFCQLAK
|
K130
|
p53 (rabbit)
|
TYSPCLNKLFCQLAK
|
K129
|
p53 (green monkey)
|
TYSPDLNKMFCQLAK
|
K132
|
|
K136-ac
|
KLFCQLAkTCPVQLW
|
|
Downstream
|
1
|
0
|
|
|
Effects on Biological Processes:
- carcinogenesis, inhibited
|
|
p53 (human)
|
kMFCQLAkTCPVQLW
|
K139-ac
|
p53 iso2 (human)
|
KMFCQLAKTCPVQLW
|
K139
|
p53 iso4 (human)
|
KMFCQLAKTCPVQLW
|
K100
|
p53 (mouse)
|
KLFCQLAkTCPVQLW
|
K136-ac
|
p53 iso2 (mouse)
|
KLFCQLAKTCPVQLW
|
K136
|
p53 (rat)
|
KLFCQLAKTCPVQLW
|
K137
|
p53 (rabbit)
|
KLFCQLAKTCPVQLW
|
K136
|
p53 (green monkey)
|
KMFCQLAKTCPVQLW
|
K139
|
|
K136
|
KLFCQLAKTCPVQLW
|
|
|
1
|
1
|
|
|
p53 (human)
|
kMFCQLAkTCPVQLW
|
K139-ub
|
p53 iso2 (human)
|
KMFCQLAKTCPVQLW
|
K139
|
p53 iso4 (human)
|
KMFCQLAKTCPVQLW
|
K100
|
p53 (mouse)
|
KLFCQLAKTCPVQLW
|
K136
|
p53 iso2 (mouse)
|
KLFCQLAKTCPVQLW
|
K136
|
p53 (rat)
|
KLFCQLAKTCPVQLW
|
K137
|
p53 (rabbit)
|
KLFCQLAKTCPVQLW
|
K136
|
p53 (green monkey)
|
KMFCQLAKTCPVQLW
|
K139
|
|
A146
|
PVQLWVSATPPAGsR
|
|
|
3
|
1
|
|
|
p53 (human)
|
PVQLWVDstPPPGtR
|
S149-p
|
p53 iso2 (human)
|
PVQLWVDSTPPPGTR
|
S149
|
p53 iso4 (human)
|
PVQLWVDSTPPPGTR
|
S110
|
p53 (mouse)
|
PVQLWVSATPPAGsR
|
A146
|
p53 iso2 (mouse)
|
PVQLWVSATPPAGSR
|
A146
|
p53 (rat)
|
PVQLWVTSTPPPGTR
|
S147
|
p53 (rabbit)
|
PVQLWVDSTPPPGTR
|
S146
|
p53 (green monkey)
|
PVQLWVDSTPPPGSR
|
S149
|
|
A146
|
PVQLWVSATPPAGsR
|
|
|
1
|
1
|
|
|
p53 (human)
|
PVQLWVDstPPPGtR
|
S149-gl
|
p53 iso2 (human)
|
PVQLWVDSTPPPGTR
|
S149
|
p53 iso4 (human)
|
PVQLWVDSTPPPGTR
|
S110
|
p53 (mouse)
|
PVQLWVSATPPAGsR
|
A146
|
p53 iso2 (mouse)
|
PVQLWVSATPPAGSR
|
A146
|
p53 (rat)
|
PVQLWVTSTPPPGTR
|
S147
|
p53 (rabbit)
|
PVQLWVDSTPPPGTR
|
S146
|
p53 (green monkey)
|
PVQLWVDSTPPPGSR
|
S149
|
|
T147
|
VQLWVSATPPAGsRV
|
|
|
4
|
8
|
|
|
p53 (human)
|
VQLWVDstPPPGtRV
|
T150-p
|
p53 iso2 (human)
|
VQLWVDSTPPPGTRV
|
T150
|
p53 iso4 (human)
|
VQLWVDSTPPPGTRV
|
T111
|
p53 (mouse)
|
VQLWVSATPPAGsRV
|
T147
|
p53 iso2 (mouse)
|
VQLWVSATPPAGSRV
|
T147
|
p53 (rat)
|
VQLWVTSTPPPGTRV
|
T148
|
p53 (rabbit)
|
VQLWVDSTPPPGTRV
|
T147
|
p53 (green monkey)
|
VQLWVDSTPPPGSRV
|
T150
|
|
S152-p
|
SATPPAGsRVRAMAI
|
Upstream
|
|
5
|
1
|
|
|
|
p53 (human)
|
DstPPPGtRVRAMAI
|
T155-p
|
p53 iso2 (human)
|
DSTPPPGTRVRAMAI
|
T155
|
p53 iso4 (human)
|
DSTPPPGTRVRAMAI
|
T116
|
p53 (mouse)
|
SATPPAGsRVRAMAI
|
S152-p
|
p53 iso2 (mouse)
|
SATPPAGSRVRAMAI
|
S152
|
p53 (rat)
|
TSTPPPGTRVRAMAI
|
T153
|
p53 (rabbit)
|
DSTPPPGTRVRAMAI
|
T152
|
p53 (green monkey)
|
DSTPPPGSRVRAMAI
|
S155
|
|
K161-ac
|
VRAMAIYkkSQHMTE
|
|
Downstream
|
13
|
1
|
|
|
Effects on Biological Processes:
- apoptosis, induced
- carcinogenesis, inhibited
- cell cycle regulation
- transcription, induced
|
|
p53 (human)
|
VRAMAIYkQSQHMTE
|
K164-ac
|
p53 iso2 (human)
|
VRAMAIYKQSQHMTE
|
K164
|
p53 iso4 (human)
|
VRAMAIYKQSQHMTE
|
K125
|
p53 (mouse)
|
VRAMAIYkkSQHMTE
|
K161-ac
|
p53 iso2 (mouse)
|
VRAMAIYkkSQHMTE
|
K161-ac
|
p53 (rat)
|
VRAMAIYKKSQHMTE
|
K162
|
p53 (rabbit)
|
VRAMAIYKKSQHMTE
|
K161
|
p53 (green monkey)
|
VRAMAIYKQSQHMTE
|
K164
|
|
K161
|
VRAMAIYKkSQHMTE
|
|
|
2
|
2
|
|
|
p53 (human)
|
VRAMAIYkQSQHMTE
|
K164-ub
|
p53 iso2 (human)
|
VRAMAIYKQSQHMTE
|
K164
|
p53 iso4 (human)
|
VRAMAIYKQSQHMTE
|
K125
|
p53 (mouse)
|
VRAMAIYKkSQHMTE
|
K161
|
p53 iso2 (mouse)
|
VRAMAIYKkSQHMTE
|
K161
|
p53 (rat)
|
VRAMAIYKKSQHMTE
|
K162
|
p53 (rabbit)
|
VRAMAIYKKSQHMTE
|
K161
|
p53 (green monkey)
|
VRAMAIYKQSQHMTE
|
K164
|
|
K162-ac
|
RAMAIYkkSQHMTEV
|
|
Downstream
|
2
|
0
|
|
|
Effects on Biological Processes:
- apoptosis, induced
- carcinogenesis, inhibited
- cell cycle regulation
|
|
p53 (human)
|
RAMAIYkQSQHMTEV
|
Q165
|
p53 iso2 (human)
|
RAMAIYKQSQHMTEV
|
Q165
|
p53 iso4 (human)
|
RAMAIYKQSQHMTEV
|
Q126
|
p53 (mouse)
|
RAMAIYkkSQHMTEV
|
K162-ac
|
p53 iso2 (mouse)
|
RAMAIYkkSQHMTEV
|
K162-ac
|
p53 (rat)
|
RAMAIYKKSQHMTEV
|
K163
|
p53 (rabbit)
|
RAMAIYKKSQHMTEV
|
K162
|
p53 (green monkey)
|
RAMAIYKQSQHMTEV
|
Q165
|
|
S180-p
|
CPHHERCsDGDGLAP
|
|
Downstream
|
3
|
1
|
|
|
Effects on Modified Protein
- molecular association, regulation
|
Effects on Biological Processes:
- cell growth, induced
- transcription, inhibited
|
|
p53 (human)
|
CPHHERCsDsDGLAP
|
S183-p
|
p53 iso2 (human)
|
CPHHERCSDSDGLAP
|
S183
|
p53 iso4 (human)
|
CPHHERCSDSDGLAP
|
S144
|
p53 (mouse)
|
CPHHERCsDGDGLAP
|
S180-p
|
p53 iso2 (mouse)
|
CPHHERCSDGDGLAP
|
S180
|
p53 (rat)
|
CPHHERCSDGDGLAP
|
S181
|
p53 (rabbit)
|
CPHHERCSDSDGLAP
|
S180
|
p53 (green monkey)
|
CPHHERCSDSDGLAP
|
S183
|
|
G182
|
HHERCsDGDGLAPPQ
|
|
|
1
|
0
|
|
|
p53 (human)
|
HHERCsDsDGLAPPQ
|
S185-p
|
p53 iso2 (human)
|
HHERCSDSDGLAPPQ
|
S185
|
p53 iso4 (human)
|
HHERCSDSDGLAPPQ
|
S146
|
p53 (mouse)
|
HHERCsDGDGLAPPQ
|
G182
|
p53 iso2 (mouse)
|
HHERCSDGDGLAPPQ
|
G182
|
p53 (rat)
|
HHERCSDGDGLAPPQ
|
G183
|
p53 (rabbit)
|
HHERCSDSDGLAPPQ
|
S182
|
p53 (green monkey)
|
HHERCSDSDGLAPPQ
|
S185
|
|
R206
|
YPEYLEDRQTFRHSV
|
|
|
0
|
2
|
|
|
p53 (human)
|
RVEYLDDrNtFrHsV
|
R209-m1
|
p53 iso2 (human)
|
RVEYLDDRNTFRHSV
|
R209
|
p53 iso4 (human)
|
RVEYLDDRNTFRHSV
|
R170
|
p53 (mouse)
|
YPEYLEDRQTFRHSV
|
R206
|
p53 iso2 (mouse)
|
YPEYLEDRQTFRHSV
|
R206
|
p53 (rat)
|
YAEYLDDRQTFRHSV
|
R207
|
p53 (rabbit)
|
RAEYLDDRNTFRHSV
|
R206
|
p53 (green monkey)
|
RVEYSDDRNTFRHSV
|
R209
|
|
T208
|
EYLEDRQTFRHSVVV
|
|
|
1
|
0
|
|
|
p53 (human)
|
EYLDDrNtFrHsVVV
|
T211-p
|
p53 iso2 (human)
|
EYLDDRNTFRHSVVV
|
T211
|
p53 iso4 (human)
|
EYLDDRNTFRHSVVV
|
T172
|
p53 (mouse)
|
EYLEDRQTFRHSVVV
|
T208
|
p53 iso2 (mouse)
|
EYLEDRQTFRHSVVV
|
T208
|
p53 (rat)
|
EYLDDRQTFRHSVVV
|
T209
|
p53 (rabbit)
|
EYLDDRNTFRHSVVV
|
T208
|
p53 (green monkey)
|
EYSDDRNTFRHSVVV
|
T211
|
|
R210
|
LEDRQTFRHSVVVPY
|
|
|
0
|
1
|
|
|
p53 (human)
|
LDDrNtFrHsVVVPy
|
R213-m1
|
p53 iso2 (human)
|
LDDRNTFRHSVVVPY
|
R213
|
p53 iso4 (human)
|
LDDRNTFRHSVVVPY
|
R174
|
p53 (mouse)
|
LEDRQTFRHSVVVPY
|
R210
|
p53 iso2 (mouse)
|
LEDRQTFRHSVVVPY
|
R210
|
p53 (rat)
|
LDDRQTFRHSVVVPY
|
R211
|
p53 (rabbit)
|
LDDRNTFRHSVVVPY
|
R210
|
p53 (green monkey)
|
SDDRNTFRHSVVVPY
|
R213
|
|
S212
|
DRQTFRHSVVVPYEP
|
|
|
6
|
0
|
|
|
p53 (human)
|
DrNtFrHsVVVPyEP
|
S215-p
|
p53 iso2 (human)
|
DRNTFRHSVVVPYEP
|
S215
|
p53 iso4 (human)
|
DRNTFRHSVVVPYEP
|
S176
|
p53 (mouse)
|
DRQTFRHSVVVPYEP
|
S212
|
p53 iso2 (mouse)
|
DRQTFRHSVVVPYEP
|
S212
|
p53 (rat)
|
DRQTFRHSVVVPYEP
|
S213
|
p53 (rabbit)
|
DRNTFRHSVVVPYEP
|
S212
|
p53 (green monkey)
|
DRNTFRHSVVVPYEP
|
S215
|
|
Y217
|
RHSVVVPYEPPEAGS
|
|
|
1
|
0
|
|
|
p53 (human)
|
rHsVVVPyEPPEVGS
|
Y220-p
|
p53 iso2 (human)
|
RHSVVVPYEPPEVGS
|
Y220
|
p53 iso4 (human)
|
RHSVVVPYEPPEVGS
|
Y181
|
p53 (mouse)
|
RHSVVVPYEPPEAGS
|
Y217
|
p53 iso2 (mouse)
|
RHSVVVPYEPPEAGS
|
Y217
|
p53 (rat)
|
RHSVVVPYEPPEVGS
|
Y218
|
p53 (rabbit)
|
RHSVVVPYEPPEVGS
|
Y217
|
p53 (green monkey)
|
RHSVVVPYEPPEVGS
|
Y220
|
|
Y226-p
|
PPEAGSEyTTIHyKY
|
|
|
0
|
1
|
|
|
p53 (human)
|
PPEVGSDCTTIHYNY
|
C229
|
p53 iso2 (human)
|
PPEVGSDCTTIHYNY
|
C229
|
p53 iso4 (human)
|
PPEVGSDCTTIHYNY
|
C190
|
p53 (mouse)
|
PPEAGSEyTTIHyKY
|
Y226-p
|
p53 iso2 (mouse)
|
PPEAGSEYTTIHYKY
|
Y226
|
p53 (rat)
|
PPEVGSDYTTIHYKY
|
Y227
|
p53 (rabbit)
|
PPEVGSDCTTIHYNY
|
C226
|
p53 (green monkey)
|
PPEVGSDCTTIHYNY
|
C229
|
|
Y231-p
|
SEyTTIHyKYMCNSS
|
Upstream
|
|
0
|
1
|
|
|
|
p53 (human)
|
SDCTTIHYNYMCNSS
|
Y234
|
p53 iso2 (human)
|
SDCTTIHYNYMCNSS
|
Y234
|
p53 iso4 (human)
|
SDCTTIHYNYMCNSS
|
Y195
|
p53 (mouse)
|
SEyTTIHyKYMCNSS
|
Y231-p
|
p53 iso2 (mouse)
|
SEYTTIHYKYMCNSS
|
Y231
|
p53 (rat)
|
SDYTTIHYKYMCNSS
|
Y232
|
p53 (rabbit)
|
SDCTTIHYNYMCNSS
|
Y231
|
p53 (green monkey)
|
SDCTTIHYNYMCNSS
|
Y234
|
|
R246
|
CMGGMNRRPILTIIT
|
|
|
3
|
0
|
|
|
p53 (human)
|
CMGGMNRrPILTIIT
|
R249-p
|
p53 iso2 (human)
|
CMGGMNRRPILTIIT
|
R249
|
p53 iso4 (human)
|
CMGGMNRRPILTIIT
|
R210
|
p53 (mouse)
|
CMGGMNRRPILTIIT
|
R246
|
p53 iso2 (mouse)
|
CMGGMNRRPILTIIT
|
R246
|
p53 (rat)
|
CMGGMNRRPILTIIT
|
R247
|
p53 (rabbit)
|
CMGGMNRRPILTIIT
|
R246
|
p53 (green monkey)
|
CMGGMNRRPILTIIT
|
R249
|
|
S266
|
GNLLGRDSFEVRVCA
|
|
|
3
|
1
|
|
|
p53 (human)
|
GNLLGRNsFEVRVCA
|
S269-p
|
p53 iso2 (human)
|
GNLLGRNSFEVRVCA
|
S269
|
p53 iso4 (human)
|
GNLLGRNSFEVRVCA
|
S230
|
p53 (mouse)
|
GNLLGRDSFEVRVCA
|
S266
|
p53 iso2 (mouse)
|
GNLLGRDSFEVRVCA
|
S266
|
p53 (rat)
|
GNLLGRDSFEVRVCA
|
S267
|
p53 (rabbit)
|
GNLLGRNSFEVRVCA
|
S266
|
p53 (green monkey)
|
GNLLGRNSFEVRVCA
|
S269
|
|
T281
|
CPGRDRRTEEENFRK
|
|
|
1
|
1
|
|
|
p53 (human)
|
CPGRDRRtEEENLrk
|
T284-p
|
p53 iso2 (human)
|
CPGRDRRTEEENLRK
|
T284
|
p53 iso4 (human)
|
CPGRDRRTEEENLRK
|
T245
|
p53 (mouse)
|
CPGRDRRTEEENFRK
|
T281
|
p53 iso2 (mouse)
|
CPGRDRRTEEENFRK
|
T281
|
p53 (rat)
|
CPGRDRRTEEENFRK
|
T282
|
p53 (rabbit)
|
CPGRDRRTEEENFRK
|
T281
|
p53 (green monkey)
|
CPGRDRRTEEENFRK
|
T284
|
|
R287
|
RTEEENFRKkEVLCP
|
|
|
0
|
1
|
|
|
p53 (human)
|
RtEEENLrkkGEPHH
|
R290-m1
|
p53 iso2 (human)
|
RTEEENLRKKGEPHH
|
R290
|
p53 iso4 (human)
|
RTEEENLRKKGEPHH
|
R251
|
p53 (mouse)
|
RTEEENFRKkEVLCP
|
R287
|
p53 iso2 (mouse)
|
RTEEENFRKKEVLCP
|
R287
|
p53 (rat)
|
RTEEENFRKKEEHCP
|
R288
|
p53 (rabbit)
|
RTEEENFRKKGEPCP
|
R287
|
p53 (green monkey)
|
RTEEENFRKKGEPCH
|
R290
|
|
K288
|
TEEENFRKkEVLCPE
|
|
|
2
|
0
|
|
|
p53 (human)
|
tEEENLrkkGEPHHE
|
K291-ub
|
p53 iso2 (human)
|
TEEENLRKKGEPHHE
|
K291
|
p53 iso4 (human)
|
TEEENLRKKGEPHHE
|
K252
|
p53 (mouse)
|
TEEENFRKkEVLCPE
|
K288
|
p53 iso2 (mouse)
|
TEEENFRKKEVLCPE
|
K288
|
p53 (rat)
|
TEEENFRKKEEHCPE
|
K289
|
p53 (rabbit)
|
TEEENFRKKGEPCPE
|
K288
|
p53 (green monkey)
|
TEEENFRKKGEPCHE
|
K291
|
|
K289
|
EEENFRKKEVLCPEL
|
|
|
1
|
4
|
|
|
p53 (human)
|
EEENLrkkGEPHHEL
|
K292-ac
|
p53 iso2 (human)
|
EEENLRKKGEPHHEL
|
K292
|
p53 iso4 (human)
|
EEENLRKKGEPHHEL
|
K253
|
p53 (mouse)
|
EEENFRKKEVLCPEL
|
K289
|
p53 iso2 (mouse)
|
EEENFRKKEVLCPEL
|
K289
|
p53 (rat)
|
EEENFRKKEEHCPEL
|
K290
|
p53 (rabbit)
|
EEENFRKKGEPCPEL
|
K289
|
p53 (green monkey)
|
EEENFRKKGEPCHEL
|
K292
|
|
K289-ub
|
EEENFRKkEVLCPEL
|
|
|
3
|
7
|
|
|
p53 (human)
|
EEENLrkkGEPHHEL
|
K292-ub
|
p53 iso2 (human)
|
EEENLRKKGEPHHEL
|
K292
|
p53 iso4 (human)
|
EEENLRKKGEPHHEL
|
K253
|
p53 (mouse)
|
EEENFRKkEVLCPEL
|
K289-ub
|
p53 iso2 (mouse)
|
EEENFRKKEVLCPEL
|
K289
|
p53 (rat)
|
EEENFRKKEEHCPEL
|
K290
|
p53 (rabbit)
|
EEENFRKKGEPCPEL
|
K289
|
p53 (green monkey)
|
EEENFRKKGEPCHEL
|
K292
|
|
S300-p
|
CPELPPGsAkRALPT
|
|
|
0
|
1
|
|
|
p53 (human)
|
HHELPPGStkRALPN
|
S303
|
p53 iso2 (human)
|
HHELPPGSTKRALPN
|
S303
|
p53 iso4 (human)
|
HHELPPGSTKRALPN
|
S264
|
p53 (mouse)
|
CPELPPGsAkRALPT
|
S300-p
|
p53 iso2 (mouse)
|
CPELPPGSAKRALPT
|
S300
|
p53 (rat)
|
CPELPPGSAKRALPT
|
S301
|
p53 (rabbit)
|
CPELPPGSSKRALPT
|
S300
|
p53 (green monkey)
|
CHELPPGSTkRALPN
|
S303
|
|
A301
|
PELPPGsAkRALPTC
|
|
|
2
|
0
|
|
|
p53 (human)
|
HELPPGStkRALPNN
|
T304-p
|
p53 iso2 (human)
|
HELPPGSTKRALPNN
|
T304
|
p53 iso4 (human)
|
HELPPGSTKRALPNN
|
T265
|
p53 (mouse)
|
PELPPGsAkRALPTC
|
A301
|
p53 iso2 (mouse)
|
PELPPGSAKRALPTC
|
A301
|
p53 (rat)
|
PELPPGSAKRALPTS
|
A302
|
p53 (rabbit)
|
PELPPGSSKRALPTT
|
S301
|
p53 (green monkey)
|
HELPPGSTkRALPNN
|
T304
|
|
K302-ac
|
ELPPGsAkRALPTCT
|
|
|
7
|
16
|
|
|
p53 (human)
|
ELPPGStkRALPNNt
|
K305-ac
|
p53 iso2 (human)
|
ELPPGSTKRALPNNT
|
K305
|
p53 iso4 (human)
|
ELPPGSTKRALPNNT
|
K266
|
p53 (mouse)
|
ELPPGsAkRALPTCT
|
K302-ac
|
p53 iso2 (mouse)
|
ELPPGSAKRALPTCT
|
K302
|
p53 (rat)
|
ELPPGSAKRALPTST
|
K303
|
p53 (rabbit)
|
ELPPGSSKRALPTTT
|
K302
|
p53 (green monkey)
|
ELPPGSTkRALPNNT
|
K305-ac
|
|
K302
|
ELPPGsAKRALPTCT
|
|
|
1
|
0
|
|
|
p53 (human)
|
ELPPGStkRALPNNt
|
K305-me
|
p53 iso2 (human)
|
ELPPGSTKRALPNNT
|
K305
|
p53 iso4 (human)
|
ELPPGSTKRALPNNT
|
K266
|
p53 (mouse)
|
ELPPGsAKRALPTCT
|
K302
|
p53 iso2 (mouse)
|
ELPPGSAKRALPTCT
|
K302
|
p53 (rat)
|
ELPPGSAKRALPTST
|
K303
|
p53 (rabbit)
|
ELPPGSSKRALPTTT
|
K302
|
p53 (green monkey)
|
ELPPGSTKRALPNNT
|
K305
|
|
K302-ub
|
ELPPGsAkRALPTCT
|
|
|
0
|
23
|
|
|
p53 (human)
|
ELPPGStkRALPNNt
|
K305-ub
|
p53 iso2 (human)
|
ELPPGSTKRALPNNT
|
K305
|
p53 iso4 (human)
|
ELPPGSTKRALPNNT
|
K266
|
p53 (mouse)
|
ELPPGsAkRALPTCT
|
K302-ub
|
p53 iso2 (mouse)
|
ELPPGSAKRALPTCT
|
K302
|
p53 (rat)
|
ELPPGSAKRALPTST
|
K303
|
p53 (rabbit)
|
ELPPGSSKRALPTTT
|
K302
|
p53 (green monkey)
|
ELPPGSTKRALPNNT
|
K305
|
|
T309
|
kRALPTCTsAsPPQk
|
|
|
0
|
1
|
|
|
p53 (human)
|
kRALPNNtsssPQPk
|
T312-p
|
| |