Other Species / Isoforms
  IRSp53 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
S2-p
______MsLSRSEEM
0 1
IRSp53 (human) ______MsLSRSEEM S2-p
IRSp53 iso2 (human) ______MSLSRSEEM S2
IRSp53 iso4 (human) ______MSLSRSEEM S2
IRSp53 iso5 (human) ______MSLSRSEEM S2
IRSp53 (mouse) ______MsLSRSEEM S2-p
IRSp53 iso2 (mouse) ______MSLSRSEEM S2
IRSp53 (rat) ______MSLSRSEEM S2
Y17-p
HRLTENVyKTIMEQF
0 5
IRSp53 (human) HRLTENVyKTIMEQF Y17-p
IRSp53 iso2 (human) HRLTENVYKTIMEQF Y17
IRSp53 iso4 (human) HRLTENVYKTIMEQF Y17
IRSp53 iso5 (human) HRLTENVYKTIMEQF Y17
IRSp53 (mouse) HRLTENVYKTIMEQF Y17
IRSp53 iso2 (mouse) HRLTENVYKTIMEQF Y17
IRSp53 (rat) HRLTENVYKTIMEQF Y17
K40-ub
AMGKNYEkALAGVTY
0 1
IRSp53 (human) AMGKNYEkALAGVTY K40-ub
IRSp53 iso2 (human) AMGKNYEKALAGVTY K40
IRSp53 iso4 (human) AMGKNYEKALAGVTY K40
IRSp53 iso5 (human) AMGKNYEKALAGVTY K40
IRSp53 (mouse) AMGKNYEKALAGVTF K40
IRSp53 iso2 (mouse) AMGKNYEKALAGVTF K40
IRSp53 (rat) AMGKNYEKALAGVTF K40
Y52-p
VTYAAKGyFDALVkM
0 1
IRSp53 (human) VTYAAKGyFDALVkM Y52-p
IRSp53 iso2 (human) VTYAAKGYFDALVKM Y52
IRSp53 iso4 (human) VTYAAKGYFDALVKM Y52
IRSp53 iso5 (human) VTYAAKGYFDALVKM Y52
IRSp53 (mouse) VTFAAKGYFDALVKM Y52
IRSp53 iso2 (mouse) VTFAAKGYFDALVKM Y52
IRSp53 (rat) VTFAAKGYFDALVKM Y52
K58-ub
GyFDALVkMGELASE
0 1
IRSp53 (human) GyFDALVkMGELASE K58-ub
IRSp53 iso2 (human) GYFDALVKMGELASE K58
IRSp53 iso4 (human) GYFDALVKMGELASE K58
IRSp53 iso5 (human) GYFDALVKMGELASE K58
IRSp53 (mouse) GYFDALVKMGELASE K58
IRSp53 iso2 (mouse) GYFDALVKMGELASE K58
IRSp53 (rat) GYFDALVKMGELASE K58
K70-ub
ASESQGSkELGDVLF
0 2
IRSp53 (human) ASESQGSkELGDVLF K70-ub
IRSp53 iso2 (human) ASESQGSKELGDVLF K70
IRSp53 iso4 (human) ASESQGSKELGDVLF K70
IRSp53 iso5 (human) ASESQGSKELGDVLF K70
IRSp53 (mouse) ASESQGSkELGDVLF K70-ub
IRSp53 iso2 (mouse) ASESQGSKELGDVLF K70
IRSp53 (rat) ASESQGSKELGDVLF K70
K108-ub
LLTQLEQkVELDSRY
0 1
IRSp53 (human) LLTQLEQkVELDSRY K108-ub
IRSp53 iso2 (human) LLTQLEQKVELDSRY K108
IRSp53 iso4 (human) LLTQLEQKVELDSRY K108
IRSp53 iso5 (human) LLTQLEQKVELDSRY K108
IRSp53 (mouse) LLTQLEQKVELDSRY K108
IRSp53 iso2 (mouse) LLTQLEQKVELDSRY K108
IRSp53 (rat) LLTQLEQKVELDSRY K108
K121-ub
RYLSAALkKYQtEQR
0 1
IRSp53 (human) RYLSAALkKYQtEQR K121-ub
IRSp53 iso2 (human) RYLSAALKKYQTEQR K121
IRSp53 iso4 (human) RYLSAALKKYQTEQR K121
IRSp53 iso5 (human) RYLSAALKKYQTEQR K121
IRSp53 (mouse) RYLSAALKKYQTEQR K121
IRSp53 iso2 (mouse) RYLSAALKKYQTEQR K121
IRSp53 (rat) RYLSAALKKYQTEQR K121
T125-p
AALkKYQtEQRSKGD
0 1
IRSp53 (human) AALkKYQtEQRSKGD T125-p
IRSp53 iso2 (human) AALKKYQTEQRSKGD T125
IRSp53 iso4 (human) AALKKYQTEQRSKGD T125
IRSp53 iso5 (human) AALKKYQTEQRSKGD T125
IRSp53 (mouse) AALKKYQTEQRSKGD T125
IRSp53 iso2 (mouse) AALKKYQTEQRSKGD T125
IRSp53 (rat) AALKKYQTEQRSKGD T125
S151-p
LRKKSQGsKNPQKyS
0 1
IRSp53 (human) LRKKSQGsKNPQKyS S151-p
IRSp53 iso2 (human) LRKKSQGSKNPQKYS S151
IRSp53 iso4 (human) LRKKSQGSKNPQKYS S151
IRSp53 iso5 (human) LRKKSQGSKNPQKYS S151
IRSp53 (mouse) LRKKSQGSKNPQKYS S151
IRSp53 iso2 (mouse) LRKKSQGSKNPQKYS S151
IRSp53 (rat) LRKKSQGSKNPQKYS S151
Y157-p
GsKNPQKySDkELQy
0 1
IRSp53 (human) GsKNPQKySDkELQy Y157-p
IRSp53 iso2 (human) GSKNPQKYSDKELQY Y157
IRSp53 iso4 (human) GSKNPQKYSDKELQY Y157
IRSp53 iso5 (human) GSKNPQKYSDKELQY Y157
IRSp53 (mouse) GSKNPQKYSDKELQY Y157
IRSp53 iso2 (mouse) GSKNPQKYSDKELQY Y157
IRSp53 (rat) GSKNPQKYSDkELQY Y157
K160-ac
NPQKySDkELQyIDA
0 2
IRSp53 (human) NPQKySDkELQyIDA K160-ac
IRSp53 iso2 (human) NPQKYSDKELQYIDA K160
IRSp53 iso4 (human) NPQKYSDKELQYIDA K160
IRSp53 iso5 (human) NPQKYSDKELQYIDA K160
IRSp53 (mouse) NPQKYSDKELQYIDA K160
IRSp53 iso2 (mouse) NPQKYSDKELQYIDA K160
IRSp53 (rat) NPQKYSDkELQYIDA K160-ac
K160-ub
NPQKySDkELQyIDA
0 3
IRSp53 (human) NPQKySDkELQyIDA K160-ub
IRSp53 iso2 (human) NPQKYSDKELQYIDA K160
IRSp53 iso4 (human) NPQKYSDKELQYIDA K160
IRSp53 iso5 (human) NPQKYSDKELQYIDA K160
IRSp53 (mouse) NPQKYSDKELQYIDA K160
IRSp53 iso2 (mouse) NPQKYSDKELQYIDA K160
IRSp53 (rat) NPQKYSDKELQYIDA K160
Y164-p
ySDkELQyIDAISNk
Upstream
0 47
Treatment
  • erlotinib
IRSp53 (human) ySDkELQyIDAISNk Y164-p
IRSp53 iso2 (human) YSDKELQYIDAISNK Y164
IRSp53 iso4 (human) YSDKELQYIDAISNK Y164
IRSp53 iso5 (human) YSDKELQYIDAISNK Y164
IRSp53 (mouse) YSDKELQYIDAISNk Y164
IRSp53 iso2 (mouse) YSDKELQYIDAISNK Y164
IRSp53 (rat) YSDkELQYIDAISNk Y164
K171-ac
yIDAISNkQGELENy
0 2
IRSp53 (human) yIDAISNkQGELENy K171-ac
IRSp53 iso2 (human) YIDAISNKQGELENY K171
IRSp53 iso4 (human) YIDAISNKQGELENY K171
IRSp53 iso5 (human) YIDAISNKQGELENY K171
IRSp53 (mouse) YIDAISNKQGELENY K171
IRSp53 iso2 (mouse) YIDAISNKQGELENY K171
IRSp53 (rat) YIDAISNkQGELENY K171-ac
K171-ub
yIDAISNkQGELENy
0 3
IRSp53 (human) yIDAISNkQGELENy K171-ub
IRSp53 iso2 (human) YIDAISNKQGELENY K171
IRSp53 iso4 (human) YIDAISNKQGELENY K171
IRSp53 iso5 (human) YIDAISNKQGELENY K171
IRSp53 (mouse) YIDAISNkQGELENY K171-ub
IRSp53 iso2 (mouse) YIDAISNKQGELENY K171
IRSp53 (rat) YIDAISNKQGELENY K171
Y178-p
kQGELENyVsDGYkT
Upstream
0 8
Treatment
  • ephrin_B1
IRSp53 (human) kQGELENyVsDGYkT Y178-p
IRSp53 iso2 (human) KQGELENYVSDGYKT Y178
IRSp53 iso4 (human) KQGELENYVSDGYKT Y178
IRSp53 iso5 (human) KQGELENYVSDGYKT Y178
IRSp53 (mouse) kQGELENYVSDGYKT Y178
IRSp53 iso2 (mouse) KQGELENYVSDGYKT Y178
IRSp53 (rat) kQGELENYVSDGYKT Y178
S180-p
GELENyVsDGYkTAL
0 2
IRSp53 (human) GELENyVsDGYkTAL S180-p
IRSp53 iso2 (human) GELENYVSDGYKTAL S180
IRSp53 iso4 (human) GELENYVSDGYKTAL S180
IRSp53 iso5 (human) GELENYVSDGYKTAL S180
IRSp53 (mouse) GELENYVSDGYKTAL S180
IRSp53 iso2 (mouse) GELENYVSDGYKTAL S180
IRSp53 (rat) GELENYVSDGYKTAL S180
K184-ub
NyVsDGYkTALtEER
0 2
IRSp53 (human) NyVsDGYkTALtEER K184-ub
IRSp53 iso2 (human) NYVSDGYKTALTEER K184
IRSp53 iso4 (human) NYVSDGYKTALTEER K184
IRSp53 iso5 (human) NYVSDGYKTALTEER K184
IRSp53 (mouse) NYVSDGYKTALTEER K184
IRSp53 iso2 (mouse) NYVSDGYKTALTEER K184
IRSp53 (rat) NYVSDGYKTALTEER K184
T188-p
DGYkTALtEERRRFC
0 1
IRSp53 (human) DGYkTALtEERRRFC T188-p
IRSp53 iso2 (human) DGYKTALTEERRRFC T188
IRSp53 iso4 (human) DGYKTALTEERRRFC T188
IRSp53 iso5 (human) DGYKTALTEERRRFC T188
IRSp53 (mouse) DGYKTALTEERRRFC T188
IRSp53 iso2 (mouse) DGYKTALTEERRRFC T188
IRSp53 (rat) DGYKTALTEERRRFC T188
K206-ub
EKQCAVAkNSAAYHS
0 1
IRSp53 (human) EKQCAVAkNSAAYHS K206-ub
IRSp53 iso2 (human) EKQCAVAKNSAAYHS K206
IRSp53 iso4 (human) EKQCAVAKNSAAYHS K206
IRSp53 iso5 (human) EKQCAVAKNSAAYHS K206
IRSp53 (mouse) EKQCAVAKNSAAYHS K206
IRSp53 iso2 (mouse) EKQCAVAKNSAAYHS K206
IRSp53 (rat) EKQCAVAKNSAAYHS K206
K216-ub
AAYHSKGkELLAQKL
0 1
IRSp53 (human) AAYHSKGkELLAQKL K216-ub
IRSp53 iso2 (human) AAYHSKGKELLAQKL K216
IRSp53 iso4 (human) AAYHSKGKELLAQKL K216
IRSp53 iso5 (human) AAYHSKGKELLAQKL K216
IRSp53 (mouse) AAYHSKGKELLAQKL K216
IRSp53 iso2 (mouse) AAYHSKGKELLAQKL K216
IRSp53 (rat) AAYHSKGKELLAQKL K216
K235-ub
QACADPSkIPERAVQ
0 1
IRSp53 (human) QACADPSkIPERAVQ K235-ub
IRSp53 iso2 (human) QACADPSKIPERAVQ K235
IRSp53 iso4 (human) QACADPSKIPERAVQ K235
IRSp53 iso5 (human) QACADPSKIPERAVQ K235
IRSp53 (mouse) QACADPNKIPDRAVQ K235
IRSp53 iso2 (mouse) QACADPNKIPDRAVQ K235
IRSp53 (rat) QACADPNKIPDRAAQ K235
T253-p
QVASNGAtLPsALsA
0 2
IRSp53 (human) QVASNGAtLPsALsA T253-p
IRSp53 iso2 (human) QVASNGATLPSALSA T253
IRSp53 iso4 (human) QVASNGATLPSALSA T253
IRSp53 iso5 (human) QVASNGATLPSALSA T253
IRSp53 (mouse) MANSNGSILPSALsA I254
IRSp53 iso2 (mouse) MANSNGSILPSALSA I254
IRSp53 (rat) MANSNGSILPSALSA I254
S256-p
SNGAtLPsALsAsKs
0 1
IRSp53 (human) SNGAtLPsALsAsKs S256-p
IRSp53 iso2 (human) SNGATLPSALSASKS S256
IRSp53 iso4 (human) SNGATLPSALSASKS S256
IRSp53 iso5 (human) SNGATLPSALSASKS S256
IRSp53 (mouse) SNGSILPSALsAsKs S257
IRSp53 iso2 (mouse) SNGSILPSALSASKS S257
IRSp53 (rat) SNGSILPSALSASKS S257
S259-p
AtLPsALsAsKsNLV
0 2
IRSp53 (human) AtLPsALsAsKsNLV S259-p
IRSp53 iso2 (human) ATLPSALSASKSNLV S259
IRSp53 iso4 (human) ATLPSALSASKSNLV S259
IRSp53 iso5 (human) ATLPSALSASKSNLV S259
IRSp53 (mouse) SILPSALsAsKsNLV S260-p
IRSp53 iso2 (mouse) SILPSALSASKSNLV S260
IRSp53 (rat) SILPSALSASKSNLV S260
S261-p
LPsALsAsKsNLVIS
0 7
IRSp53 (human) LPsALsAsKsNLVIS S261-p
IRSp53 iso2 (human) LPSALSASKSNLVIS S261
IRSp53 iso4 (human) LPSALSASKSNLVIS S261
IRSp53 iso5 (human) LPSALSASKSNLVIS S261
IRSp53 (mouse) LPSALsAsKsNLVIS S262-p
IRSp53 iso2 (mouse) LPSALSASKSNLVIS S262
IRSp53 (rat) LPSALSASKSNLVIS S262
S263-p
sALsAsKsNLVISDP
0 5
IRSp53 (human) sALsAsKsNLVISDP S263-p
IRSp53 iso2 (human) SALSASKSNLVISDP S263
IRSp53 iso4 (human) SALSASKSNLVISDP S263
IRSp53 iso5 (human) SALSASKSNLVISDP S263
IRSp53 (mouse) SALsAsKsNLVISDP S264-p
IRSp53 iso2 (mouse) SALSASKSNLVISDP S264
IRSp53 (rat) SALSASKSNLVISDP S264
K275-ub
SDPIPGAkPLPVPPE
0 5
IRSp53 (human) SDPIPGAkPLPVPPE K275-ub
IRSp53 iso2 (human) SDPIPGAKPLPVPPE K275
IRSp53 iso4 (human) SDPIPGAKPLPVPPE K275
IRSp53 iso5 (human) SDPIPGAKPLPVPPE K275
IRSp53 (mouse) SDPIPGAKPLPVPPE K276
IRSp53 iso2 (mouse) SDPIPGAKPLPVPPE K276
IRSp53 (rat) SDPIPGAkPLPVPPE K276-ub
S291-p
APFVGRMsAQEStPI
0 1
IRSp53 (human) APFVGRMsAQEStPI S291-p
IRSp53 iso2 (human) APFVGRMSAQESTPI S291
IRSp53 iso4 (human) APFVGRMSAQESTPI S291
IRSp53 iso5 (human) APFVGRMSAQESTPI S291
IRSp53 (mouse) APFVGRMSAQENVPV S292
IRSp53 iso2 (mouse) APFVGRMSAQENVPV S292
IRSp53 (rat) APFVGRMSAQENVPV S292
T296-p
RMsAQEStPIMNGVT
Upstream
0 3
Treatment
  • MLN8054
IRSp53 (human) RMsAQEStPIMNGVT T296-p
IRSp53 iso2 (human) RMSAQESTPIMNGVT T296
IRSp53 iso4 (human) RMSAQESTPIMNGVT T296
IRSp53 iso5 (human) RMSAQESTPIMNGVT T296
IRSp53 (mouse) RMSAQENVPVMNGVA V297
IRSp53 iso2 (mouse) RMSAQENVPVMNGVA V297
IRSp53 (rat) RMSAQENVPVMNGVA V297
Y310-p
TGPDGEDysPWADRK
Upstream
1 24
Regulatory protein:
  • INSR (human)
Treatment
  • ephrin_B1
  • insulin
  • Su11274
IRSp53 (human) TGPDGEDysPWADRK Y310-p
IRSp53 iso2 (human) TGPDGEDYSPWADRK Y310
IRSp53 iso4 (human) TGPDGEDYSPWADRK Y310
IRSp53 iso5 (human) TGPDGEDYSPWADRK Y310
IRSp53 (mouse) AGPDSEDYNPWADRK Y311
IRSp53 iso2 (mouse) AGPDSEDYNPWADRK Y311
IRSp53 (rat) AGADSEDYNPWADRK Y311
S311-p
GPDGEDysPWADRKA
Upstream
0 9
Treatment
  • MLN8054
IRSp53 (human) GPDGEDysPWADRKA S311-p
IRSp53 iso2 (human) GPDGEDYSPWADRKA S311
IRSp53 iso4 (human) GPDGEDYSPWADRKA S311
IRSp53 iso5 (human) GPDGEDYSPWADRKA S311
IRSp53 (mouse) GPDSEDYNPWADRKA N312
IRSp53 iso2 (mouse) GPDSEDYNPWADRKA N312
IRSp53 (rat) GADSEDYNPWADRKA N312
K322-ub
DRKAAQPksLsPPQs
0 1
IRSp53 (human) DRKAAQPksLsPPQs K322-ub
IRSp53 iso2 (human) DRKAAQPKSLSPPQS K322
IRSp53 iso4 (human) DRKAAQPKSLSPPQS K322
IRSp53 iso5 (human) DRKAAQPKSLSPPQS K322
IRSp53 (mouse) DRKAAQPKsLsPPQS K323
IRSp53 iso2 (mouse) DRKAAQPKSLSPPQS K323
IRSp53 (rat) DRKAAQPKSLsPPQS K323
S323-p
RKAAQPksLsPPQsQ
Upstream
0 9
Treatment
  • ischemia
IRSp53 (human) RKAAQPksLsPPQsQ S323-p
IRSp53 iso2 (human) RKAAQPKSLSPPQSQ S323
IRSp53 iso4 (human) RKAAQPKSLSPPQSQ S323
IRSp53 iso5 (human) RKAAQPKSLSPPQSQ S323
IRSp53 (mouse) RKAAQPKsLsPPQSQ S324-p
IRSp53 iso2 (mouse) RKAAQPKSLSPPQSQ S324
IRSp53 (rat) RKAAQPKSLsPPQSQ S324
S325-p
AAQPksLsPPQsQSk
Upstream
0 37
Treatment
  • nocodazole
IRSp53 (human) AAQPksLsPPQsQSk S325-p
IRSp53 iso2 (human) AAQPKSLSPPQSQSK S325
IRSp53 iso4 (human) AAQPKSLSPPQSQSK S325
IRSp53 iso5 (human) AAQPKSLSPPQSQSK S325
IRSp53 (mouse) AAQPKsLsPPQSQSK S326-p
IRSp53 iso2 (mouse) AAQPKSLSPPQSQSK S326
IRSp53 (rat) AAQPKSLsPPQSQSK S326-p
S329-p
ksLsPPQsQSkLsDs
0 2
IRSp53 (human) ksLsPPQsQSkLsDs S329-p
IRSp53 iso2 (human) KSLSPPQSQSKLSDS S329
IRSp53 iso4 (human) KSLSPPQSQSKLSDS S329
IRSp53 iso5 (human) KSLSPPQSQSKLSDS S329
IRSp53 (mouse) KsLsPPQSQSKLsDs S330
IRSp53 iso2 (mouse) KSLSPPQSQSKLSDS S330
IRSp53 (rat) KSLsPPQSQSKLSDS S330
K332-ub
sPPQsQSkLsDsysN
0 3
IRSp53 (human) sPPQsQSkLsDsysN K332-ub
IRSp53 iso2 (human) SPPQSQSKLSDSYSN K332
IRSp53 iso4 (human) SPPQSQSKLSDSYSN K332
IRSp53 iso5 (human) SPPQSQSKLSDSYSN K332
IRSp53 (mouse) sPPQSQSKLsDsysN K333
IRSp53 iso2 (mouse) SPPQSQSKLSDSYSN K333
IRSp53 (rat) sPPQSQSKLSDSysN K333
S334-p
PQsQSkLsDsysNtL
0 4
IRSp53 (human) PQsQSkLsDsysNtL S334-p
IRSp53 iso2 (human) PQSQSKLSDSYSNTL S334
IRSp53 iso4 (human) PQSQSKLSDSYSNTL S334
IRSp53 iso5 (human) PQSQSKLSDSYSNTL S334
IRSp53 (mouse) PQSQSKLsDsysNtL S335-p
IRSp53 iso2 (mouse) PQSQSKLSDSYSNTL S335
IRSp53 (rat) PQSQSKLSDSysNTL S335
S336-p
sQSkLsDsysNtLPV
Upstream
0 19
Regulatory protein:
  • EGFR (human)
Treatment
  • AZD1152
  • BI2536
  • ischemia
  • ZM447439
IRSp53 (human) sQSkLsDsysNtLPV S336-p
IRSp53 iso2 (human) SQSKLSDSYSNTLPV S336
IRSp53 iso4 (human) SQSKLSDSYSNTLPV S336
IRSp53 iso5 (human) SQSKLSDSYSNTLPV S336
IRSp53 (mouse) SQSKLsDsysNtLPV S337-p
IRSp53 iso2 (mouse) SQSKLSDSYSNTLPV S337
IRSp53 (rat) SQSKLSDSysNTLPV S337
Y337-p
QSkLsDsysNtLPVR
Upstream
0 229
Regulatory protein:
  • EGFR (human)
Treatment
  • ephrin_B1
  • ephrin_B2
  • gefitinib
  • Su11274
IRSp53 (human) QSkLsDsysNtLPVR Y337-p
IRSp53 iso2 (human) QSKLSDSYSNTLPVR Y337
IRSp53 iso4 (human) QSKLSDSYSNTLPVR Y337
IRSp53 iso5 (human) QSKLSDSYSNTLPVR Y337
IRSp53 (mouse) QSKLsDsysNtLPVR Y338-p
IRSp53 iso2 (mouse) QSKLSDSYSNTLPVR Y338
IRSp53 (rat) QSKLSDSysNTLPVR Y338-p
S338-p
SkLsDsysNtLPVRK
Upstream
0 13
Regulatory protein:
  • PRP4 (human)
IRSp53 (human) SkLsDsysNtLPVRK S338-p
IRSp53 iso2 (human) SKLSDSYSNTLPVRK S338
IRSp53 iso4 (human) SKLSDSYSNTLPVRK S338
IRSp53 iso5 (human) SKLSDSYSNTLPVRK S338
IRSp53 (mouse) SKLsDsysNtLPVRK S339-p
IRSp53 iso2 (mouse) SKLSDSYSNTLPVRK S339
IRSp53 (rat) SKLSDSysNTLPVRK S339-p
T340-p
LsDsysNtLPVRKsV
Upstream
Downstream
1 53
Effects on Modified Protein
  • molecular association, regulation
Effects on Biological Processes:
  • cytoskeletal reorganization
Treatment
  • nocodazole
IRSp53 (human) LsDsysNtLPVRKsV T340-p
IRSp53 iso2 (human) LSDSYSNTLPVRKSV T340
IRSp53 iso4 (human) LSDSYSNTLPVRKSV T340
IRSp53 iso5 (human) LSDSYSNTLPVRKSV T340
IRSp53 (mouse) LsDsysNtLPVRKSV T341-p
IRSp53 iso2 (mouse) LSDSYSNTLPVRKSV T341
IRSp53 (rat) LSDSysNTLPVRKSV T341
S346-p
NtLPVRKsVtPkNsy
Upstream
0 2
Treatment
  • BI2536
  • MLN8054
IRSp53 (human) NtLPVRKsVtPkNsy S346-p
IRSp53 iso2 (human) NTLPVRKSVTPKNSY S346
IRSp53 iso4 (human) NTLPVRKSVTPKNSY S346
IRSp53 iso5 (human) NTLPVRKSVTPKNSY S346
IRSp53 (mouse) NtLPVRKSVtPkNsY S347
IRSp53 iso2 (mouse) NTLPVRKSVTPKNSY S347
IRSp53 (rat) NTLPVRKSVTPKNSy S347
T348-p
LPVRKsVtPkNsyAT
Upstream
0 4
Treatment
  • BI2536
  • ischemia
  • MLN8054
IRSp53 (human) LPVRKsVtPkNsyAT T348-p
IRSp53 iso2 (human) LPVRKSVTPKNSYAT T348
IRSp53 iso4 (human) LPVRKSVTPKNSYAT T348
IRSp53 iso5 (human) LPVRKSVTPKNSYAT T348
IRSp53 (mouse) LPVRKSVtPkNsYAT T349-p
IRSp53 iso2 (mouse) LPVRKSVTPKNSYAT T349
IRSp53 (rat) LPVRKSVTPKNSyAT T349
K350-ub
VRKsVtPkNsyATtE
0 2
IRSp53 (human) VRKsVtPkNsyATtE K350-ub
IRSp53 iso2 (human) VRKSVTPKNSYATTE K350
IRSp53 iso4 (human) VRKSVTPKNSYATTE K350
IRSp53 iso5 (human) VRKSVTPKNSYATTE K350
IRSp53 (mouse) VRKSVtPkNsYATTE K351-ub
IRSp53 iso2 (mouse) VRKSVTPKNSYATTE K351
IRSp53 (rat) VRKSVTPKNSyATTE K351
S352-p
KsVtPkNsyATtENk
Upstream
0 2
Treatment
  • ischemia
IRSp53 (human) KsVtPkNsyATtENk S352-p
IRSp53 iso2 (human) KSVTPKNSYATTENK S352
IRSp53 iso4 (human) KSVTPKNSYATTENK S352
IRSp53 iso5 (human) KSVTPKNSYATTENK S352
IRSp53 (mouse) KSVtPkNsYATTENk S353-p
IRSp53 iso2 (mouse) KSVTPKNSYATTENK S353
IRSp53 (rat) KSVTPKNSyATTENK S353
Y353-p
sVtPkNsyATtENkt
0 5
IRSp53 (human) sVtPkNsyATtENkt Y353-p
IRSp53 iso2 (human) SVTPKNSYATTENKT Y353
IRSp53 iso4 (human) SVTPKNSYATTENKT Y353
IRSp53 iso5 (human) SVTPKNSYATTENKT Y353
IRSp53 (mouse) SVtPkNsYATTENkt Y354
IRSp53 iso2 (mouse) SVTPKNSYATTENKT Y354
IRSp53 (rat) SVTPKNSyATTENKT Y354-p
T356-p
PkNsyATtENktLPR
0 2
IRSp53 (human) PkNsyATtENktLPR T356-p
IRSp53 iso2 (human) PKNSYATTENKTLPR T356
IRSp53 iso4 (human) PKNSYATTENKTLPR T356
IRSp53 iso5 (human) PKNSYATTENKTLPR T356
IRSp53 (mouse) PkNsYATTENktLPR T357
IRSp53 iso2 (mouse) PKNSYATTENKTLPR T357
IRSp53 (rat) PKNSyATTENKTLPR T357
K359-ub
syATtENktLPRsss
0 2
IRSp53 (human) syATtENktLPRsss K359-ub
IRSp53 iso2 (human) SYATTENKTLPRSSS K359
IRSp53 iso4 (human) SYATTENKTLPRSSS K359
IRSp53 iso5 (human) SYATTENKTLPRSSS K359
IRSp53 (mouse) sYATTENktLPRsss K360-ub
IRSp53 iso2 (mouse) SYATTENKTLPRSSS K360
IRSp53 (rat) SyATTENKTLPRSSs K360
T360-p
yATtENktLPRsssM
Upstream
Downstream
1 35
Effects on Modified Protein
  • molecular association, regulation
Effects on Biological Processes:
  • cytoskeletal reorganization
Regulatory protein:
  • TBK1 (human)
  • VHL (human)
IRSp53 (human) yATtENktLPRsssM T360-p
IRSp53 iso2 (human) YATTENKTLPRSSSM T360
IRSp53 iso4 (human) YATTENKTLPRSSSM T360
IRSp53 iso5 (human) YATTENKTLPRSSSM T360
IRSp53 (mouse) YATTENktLPRsssM T361-p
IRSp53 iso2 (mouse) YATTENKTLPRSSSM T361
IRSp53 (rat) yATTENKTLPRSSsM T361
S364-p
ENktLPRsssMAAGL
0 2
IRSp53 (human) ENktLPRsssMAAGL S364-p
IRSp53 iso2 (human) ENKTLPRSSSMAAGL S364
IRSp53 iso4 (human) ENKTLPRSSSMAAGL S364
IRSp53 iso5 (human) ENKTLPRSSSMAAGL S364
IRSp53 (mouse) ENktLPRsssMAAGL S365-p
IRSp53 iso2 (mouse) ENKTLPRSSSMAAGL S365
IRSp53 (rat) ENKTLPRSSsMAAGL S365
S365-p
NktLPRsssMAAGLE
0 10
IRSp53 (human) NktLPRsssMAAGLE S365-p
IRSp53 iso2 (human) NKTLPRSSSMAAGLE S365
IRSp53 iso4 (human) NKTLPRSSSMAAGLE S365
IRSp53 iso5 (human) NKTLPRSSSMAAGLE S365
IRSp53 (mouse) NktLPRsssMAAGLE S366-p
IRSp53 iso2 (mouse) NKTLPRSSSMAAGLE S366
IRSp53 (rat) NKTLPRSSsMAAGLE S366
S366-p
ktLPRsssMAAGLER
Upstream
Downstream
2 68
Effects on Modified Protein
  • molecular association, regulation
Effects on Biological Processes:
  • cytoskeletal reorganization
Kinase, in vitro:
  • AMPKA2 (human)
  • MARK2 (human)
Putative in vivo kinases:
  • AMPKA2 (human)
Treatment
  • EGF
  • HB-EGF
  • LPA
IRSp53 (human) ktLPRsssMAAGLER S366-p
IRSp53 iso2 (human) KTLPRSSSMAAGLER S366
IRSp53 iso4 (human) KTLPRSSSMAAGLER S366
IRSp53 iso5 (human) KTLPRSSSMAAGLER S366
IRSp53 (mouse) ktLPRsssMAAGLER S367-p
IRSp53 iso2 (mouse) KTLPRSSSMAAGLER S367
IRSp53 (rat) KTLPRSSsMAAGLER S367-p
S384-p
MRVKAIFsHAAGDNs
0 9
IRSp53 (human) MRVKAIFsHAAGDNs S384-p
IRSp53 iso2 (human) MRVKAIFSHAAGDNS S384
IRSp53 iso4 (human) MRVKAIFSHAAGDNS S384
IRSp53 iso5 (human) MRVKAIFSHAAGDNS S384
IRSp53 (mouse) MRVKAIFsHAAGDNS S385-p
IRSp53 iso2 (mouse) MRVKAIFSHAAGDNS S385
IRSp53 (rat) MRVKAIFSHAAGDNS S385
S391-p
sHAAGDNsTLLsFKE
0 1
IRSp53 (human) sHAAGDNsTLLsFKE S391-p
IRSp53 iso2 (human) SHAAGDNSTLLSFKE S391
IRSp53 iso4 (human) SHAAGDNSTLLSFKE S391
IRSp53 iso5 (human) SHAAGDNSTLLSFKE S391
IRSp53 (mouse) sHAAGDNStLLsFKE S392
IRSp53 iso2 (mouse) SHAAGDNSTLLSFKE S392
IRSp53 (rat) SHAAGDNSTLLsFKE S392
T392
HAAGDNsTLLsFKEG
0 1
IRSp53 (human) HAAGDNsTLLsFKEG T392
IRSp53 iso2 (human) HAAGDNSTLLSFKEG T392
IRSp53 iso4 (human) HAAGDNSTLLSFKEG T392
IRSp53 iso5 (human) HAAGDNSTLLSFKEG T392
IRSp53 (mouse) HAAGDNStLLsFKEG T393-p
IRSp53 iso2 (mouse) HAAGDNSTLLSFKEG T393
IRSp53 (rat) HAAGDNSTLLsFKEG T393
S395-p
GDNsTLLsFKEGDLI
0 9
IRSp53 (human) GDNsTLLsFKEGDLI S395-p
IRSp53 iso2 (human) GDNSTLLSFKEGDLI S395
IRSp53 iso4 (human) GDNSTLLSFKEGDLI S395
IRSp53 iso5 (human) GDNSTLLSFKEGDLI S395
IRSp53 (mouse) GDNStLLsFKEGDLI S396-p
IRSp53 iso2 (mouse) GDNSTLLSFKEGDLI S396
IRSp53 (rat) GDNSTLLsFKEGDLI S396-p
Y415
EARDGWHYGESEKTK
0 3
IRSp53 (human) EARDGWHYGESEKTK Y415
IRSp53 iso2 (human) EARDGWHYGESEKTK Y415
IRSp53 iso4 (human) EARDGWHYGESEKTK Y415
IRSp53 iso5 (human) EARDGWHYGESEKTK Y415
IRSp53 (mouse) EARDGWHYGESEKTK Y416
IRSp53 iso2 (mouse) EARDGWHYGESEKTK Y416
IRSp53 (rat) EARDGWHyGESEKTK Y416-p
T432-p
GWFPFSYtRVLDSDG
0 1
IRSp53 (human) GWFPFSYtRVLDSDG T432-p
IRSp53 iso2 (human) GWFPFSYTRVLDSDG T432
IRSp53 iso4 (human) GWFPFSYTRVLDSDG T432
IRSp53 iso5 (human) GWFPFSYTRVLDSDG T432
IRSp53 (mouse) GWFPFSYTRVLDSDG T433
IRSp53 iso2 (mouse) GWFPFSYTRVLDSDG T433
IRSp53 (rat) GWFPFSYTRVLDSDG T433
S440-p
RVLDSDGsDRLHMsL
0 2
IRSp53 (human) RVLDSDGsDRLHMsL S440-p
IRSp53 iso2 (human) RVLDSDGSDRLHMSL S440
IRSp53 iso4 (human) RVLDSDGSDRLHMSL S440
IRSp53 iso5 (human) RVLDSDGSDRLHMSL S440
IRSp53 (mouse) RVLDSDGsDRLHMsL S441-p
IRSp53 iso2 (mouse) RVLDSDGSDRLHMSL S441
IRSp53 (rat) RVLDSDGSDRLHMSL S441
S446-p
GsDRLHMsLQQGKss
Upstream
0 5
Treatment
  • ischemia
IRSp53 (human) GsDRLHMsLQQGKss S446-p
IRSp53 iso2 (human) GSDRLHMSLQQGKSS S446
IRSp53 iso4 (human) GSDRLHMSLQQGKSS S446
IRSp53 iso5 (human) GSDRLHMSLQQGKSS S446
IRSp53 (mouse) GsDRLHMsLQQGKss S447-p
IRSp53 iso2 (mouse) GSDRLHMSLQQGKSS S447
IRSp53 (rat) GSDRLHMSLQQGKSS S447
S452-p
MsLQQGKssstGNLL
0 4
IRSp53 (human) MsLQQGKssstGNLL S452-p
IRSp53 iso2 (human) MSLQQGKSSSTGNLL S452
IRSp53 iso4 (human) MSLQQGKSSSTGNLL S452
IRSp53 iso5 (human) MSLQQGKSSSTGNLL S452
IRSp53 (mouse) MsLQQGKssstGNLL S453-p
IRSp53 iso2 (mouse) MSLQQGKSSSTGNLL S453
IRSp53 (rat) MSLQQGKSSsTGNLL S453
S453-p
sLQQGKssstGNLLD
Upstream
1 7
Regulatory protein:
  • MARK2 (human)
IRSp53 (human) sLQQGKssstGNLLD S453-p
IRSp53 iso2 (human) SLQQGKSSSTGNLLD S453
IRSp53 iso4 (human) SLQQGKSSSTGNLLD S453
IRSp53 iso5 (human) SLQQGKSSSTGNLLD S453
IRSp53 (mouse) sLQQGKssstGNLLD S454-p
IRSp53 iso2 (mouse) SLQQGKSSSTGNLLD S454
IRSp53 (rat) SLQQGKSSsTGNLLD S454
S454-p
LQQGKssstGNLLDK
Upstream
1 28
Regulatory protein:
  • MARK2 (human)
Treatment
  • HB-EGF
  • LPA
IRSp53 (human) LQQGKssstGNLLDK S454-p
IRSp53 iso2 (human) LQQGKSSSTGNLLDK S454
IRSp53 iso4 (human) LQQGKSSSTGNLLDK S454
IRSp53 iso5 (human) LQQGKSSSTGNLLDK S454
IRSp53 (mouse) LQQGKssstGNLLDK S455-p
IRSp53 iso2 (mouse) LQQGKSSSTGNLLDK S455
IRSp53 (rat) LQQGKSSsTGNLLDK S455-p
T455-p
QQGKssstGNLLDKD
Upstream
1 5
Regulatory protein:
  • MARK2 (human)
IRSp53 (human) QQGKssstGNLLDKD T455-p
IRSp53 iso2 (human) QQGKSSSTGNLLDKD T455
IRSp53 iso4 (human) QQGKSSSTGNLLDKD T455
IRSp53 iso5 (human) QQGKSSSTGNLLDKD T455
IRSp53 (mouse) QQGKssstGNLLDKD T456-p
IRSp53 iso2 (mouse) QQGKSSSTGNLLDKD T456
IRSp53 (rat) QQGKSSsTGNLLDKD T456
T482-p
SRAFPAQtAsGFKQR
0 1
IRSp53 (human) SRAFPAQtAsGFKQR T482-p
IRSp53 iso2 (human) SRAFPAQTASGFKQR T482
IRSp53 iso4 (human) SRAFPAQTASGFKQR T482
IRSp53 iso5 (human) SRAFPAQTASGFKQR T482
IRSp53 (mouse) SRAFPTQTAGtFKQR T483
IRSp53 iso2 (mouse) SRAFPTQTAGTFKQR T483
IRSp53 (rat) SRAFPSQTAGTFKQR T483
S484-p
AFPAQtAsGFKQRPy
0 2