Other Species / Isoforms
  CTNNB1 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
K19-ub
MAMEPDRkAAVsHWQ
Downstream
1 5
Effects on Modified Protein
  • protein degradation
Effects on Biological Processes:
  • carcinogenesis, inhibited
  • cell growth, inhibited
  • transcription, inhibited
CTNNB1 (human) MAMEPDRkAAVsHWQ K19-ub
CTNNB1 (mouse) MAMEPDRkAAVsHWQ K19-ub
CTNNB1 (rat) MAMEPDRKAAVSHWQ K19
K19-ac
MAMEPDRkAAVsHWQ
Downstream
1 0
Effects on Modified Protein
  • intracellular localization
  • protein stabilization
Effects on Biological Processes:
  • carcinogenesis, inhibited
  • cell motility, induced
  • transcription, induced
CTNNB1 (human) MAMEPDRkAAVsHWQ K19-ac
CTNNB1 (mouse) MAMEPDRKAAVsHWQ K19
CTNNB1 (rat) MAMEPDRKAAVSHWQ K19
S23-p
PDRkAAVsHWQQQsy
Upstream
2 0
Regulatory protein:
  • WNT1 (human)
Treatment
  • lithium
CTNNB1 (human) PDRkAAVsHWQQQsy S23-p
CTNNB1 (mouse) PDRkAAVsHWQQQsY S23-p
CTNNB1 (rat) PDRKAAVSHWQQQSY S23
S23
PDRkAAVSHWQQQsy
0 1
CTNNB1 (human) PDRkAAVSHWQQQsy S23
CTNNB1 (mouse) PDRkAAVsHWQQQsY S23-gl
CTNNB1 (rat) PDRKAAVSHWQQQSY S23
S29-p
VsHWQQQsyLDsGIH
Upstream
Downstream
3 5
Effects on Modified Protein
  • protein degradation
Effects on Biological Processes:
  • cell motility, altered
Kinase, in vitro:
  • CK2A2 (human)
Regulatory protein:
  • WNT1 (human)
Treatment
  • lithium
CTNNB1 (human) VsHWQQQsyLDsGIH S29-p
CTNNB1 (mouse) VsHWQQQsYLDsGIH S29-p
CTNNB1 (rat) VSHWQQQSYLDsGIH S29
Y30-p
sHWQQQsyLDsGIHs
Upstream
1 39
Kinase, in vitro:
  • JAK3 (human)
Putative in vivo kinases:
  • JAK3 (human)
Treatment
  • Su11274
CTNNB1 (human) sHWQQQsyLDsGIHs Y30-p
CTNNB1 (mouse) sHWQQQsYLDsGIHs Y30
CTNNB1 (rat) SHWQQQSYLDsGIHs Y30
S33-p
QQQsyLDsGIHsGAT
Upstream
Downstream
76 5
CTNNB1 (human)
S33-p
CTNNB1 (mouse)
S33-p
CTNNB1 (rat)
S33-p
Effects on Modified Protein
  • activity, inhibited
  • intracellular localization
  • molecular association, regulation
  • protein degradation
  • ubiquitination
Effects on Biological Processes:
  • cell adhesion, altered
  • cell growth, altered
  • cytoskeletal reorganization
  • signaling pathway regulation
  • transcription, altered
  • transcription, inhibited
Kinase, in vitro:
  • GSK3A (human)
  • GSK3B (human)
  • JNK1 (human)
Phosphatases, in vitro:
  • PPP2CA (human)
Putative in vivo kinases:
  • GSK3B (human)
  • IKKA (human)
  • JNK1 (human)
Regulatory protein:
  • APC (human)
  • AurA (human)
  • axin 1 (human)
  • CDH2 (human)
  • CTNNA1 (human)
  • CTNNB1 (human)
  • DDX5 (human)
  • DKK1 (human)
  • GLIPR1 (human)
  • GSKIP (human)
  • IL24 (human)
  • Merlin (human)
  • PPP2R2A (human)
  • SFRP2 (human)
  • WNT3A (human)
  • WNT5A (human)
Treatment
  • anti-FGF19
  • calyculin_A
  • cAMP_analog
  • CHIR99021
  • CK1-7
  • colforsin
  • CTGF
  • FGF2
  • H-89
  • KY1022
  • lithium
  • LY2090314
  • MG132
  • okadaic_acid
  • SB216763
  • SB415286
  • SP600125
  • Wnt
  • Wnt3a
CTNNB1 (human) QQQsyLDsGIHsGAT S33-p
CTNNB1 (mouse) QQQsYLDsGIHsGAT S33-p
CTNNB1 (rat) QQQSYLDsGIHsGAT S33-p
S37-p
yLDsGIHsGATtTAP
Upstream
Downstream
77 15
CTNNB1 (human)
S37-p
CTNNB1 (mouse)
S37-p
CTNNB1 (rat)
S37-p
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
  • protein degradation
  • ubiquitination
Effects on Biological Processes:
  • cell adhesion, altered
  • cell growth, altered
  • cytoskeletal reorganization
  • signaling pathway regulation
  • transcription, altered
  • transcription, inhibited
Kinase, in vitro:
  • GSK3A (human)
  • GSK3B (human)
  • JNK1 (human)
Phosphatases, in vitro:
  • PPP2CA (human)
Putative in vivo kinases:
  • GSK3B (human)
  • IKKA (human)
  • JNK1 (human)
Regulatory protein:
  • AurA (human)
  • axin 1 (human)
  • CDH2 (human)
  • CTNNB1 (human)
  • DDX5 (human)
  • DKK1 (human)
  • GLIPR1 (human)
  • GSKIP (human)
  • IL24 (human)
  • Merlin (human)
  • PPP2R2A (human)
  • SFRP2 (human)
  • WNT3A (human)
  • WNT5A (human)
Treatment
  • anti-FGF19
  • calyculin_A
  • cAMP_analog
  • CK1-7
  • colforsin
  • CTGF
  • FGF2
  • H-89
  • IWR-1
  • KN-92
  • KN-93
  • KY1022
  • lithium
  • LLnL
  • LY2090314
  • MG132
  • okadaic_acid
  • SB216763
  • SP600125
  • W-5
  • W-7
  • Wnt
  • Wnt3a
CTNNB1 (human) yLDsGIHsGATtTAP S37-p
CTNNB1 (mouse) YLDsGIHsGATtTAP S37-p
CTNNB1 (rat) YLDsGIHsGATtTAP S37-p
T41-p
GIHsGATtTAPsLsG
Upstream
Downstream
68 3
CTNNB1 (human)
T41-p
CTNNB1 (mouse)
T41-p
CTNNB1 (rat)
T41-p
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
  • protein degradation
Effects on Biological Processes:
  • cell adhesion, altered
  • cell growth, altered
  • cytoskeletal reorganization
  • signaling pathway regulation
  • transcription, altered
  • transcription, inhibited
Kinase, in vitro:
  • GSK3A (human)
  • GSK3B (human)
  • JNK1 (human)
Putative in vivo kinases:
  • GSK3B (human)
  • IKKA (human)
  • JNK1 (human)
Putative upstream phosphatases:
  • PPP1CC (human)
Regulatory protein:
  • AurA (human)
  • axin 1 (human)
  • CTNNB1 (human)
  • DDX5 (human)
  • GLIPR1 (human)
  • GSKIP (human)
  • IL24 (human)
  • JNK1 (human)
  • JNK2 (human)
  • Merlin (human)
  • PPP2R2A (human)
  • SFRP2 (human)
  • SMPD3 (human)
  • WNT3A (human)
  • WNT5A (human)
Treatment
  • anti-FGF19
  • C6-ceramide
  • calyculin_A
  • cAMP_analog
  • CHIR99021
  • CK1-7
  • colforsin
  • FGF2
  • H-89
  • high_cell_density
  • IWR-1
  • lithium
  • LLnL
  • LY2090314
  • MG132
  • okadaic_acid
  • SB216763
  • SB415286
  • siRNA
  • SP600125
  • Wnt
  • Wnt3a
CTNNB1 (human) GIHsGATtTAPsLsG T41-p
CTNNB1 (mouse) GIHsGATtTAPsLsG T41-p
CTNNB1 (rat) GIHsGATtTAPsLSG T41-p
S45-p
GATtTAPsLsGkGNP
Upstream
Downstream
37 6
CTNNB1 (human)
S45-p
CTNNB1 (mouse)
S45-p
CTNNB1 (rat)
S45-p
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
  • phosphorylation
  • protein degradation
  • protein stabilization
  • ubiquitination
Effects on Biological Processes:
  • cell adhesion, altered
  • cell growth, inhibited
  • cell motility, altered
  • transcription, induced
  • transcription, inhibited
Kinase, in vitro:
  • CK1A (human)
  • CK1D (human)
  • PKACA (human)
  • PKCZ (human)
Putative in vivo kinases:
  • CK1A (human)
  • CK1A (rat)
  • CK1E (human)
  • IKKA (human)
Putative upstream phosphatases:
  • PPP1CC (human)
Regulatory protein:
  • axin 1 (human)
  • CK1A (human)
  • HDAC6 (human)
  • JNK1 (human)
  • JNK2 (human)
  • SMPD3 (human)
  • WNT5A (human)
Treatment
  • anti-FGF19
  • C6-ceramide
  • calyculin_A
  • cAMP_analog
  • CK1-7
  • CKI-7
  • H-89
  • high_cell_density
  • lithium
  • low_Ca(2+)
  • MG132
  • mutation
  • okadaic_acid
  • siRNA
  • SP600125
  • Wnt
  • Wnt3a
CTNNB1 (human) GATtTAPsLsGkGNP S45-p
CTNNB1 (mouse) GATtTAPsLsGkGNP S45-p
CTNNB1 (rat) GATtTAPsLSGKGNP S45-p
S47-p
TtTAPsLsGkGNPEE
1 2
CTNNB1 (human) TtTAPsLsGkGNPEE S47-p
CTNNB1 (mouse) TtTAPsLsGkGNPEE S47-p
CTNNB1 (rat) TtTAPsLSGKGNPEE S47
K49-ac
TAPsLsGkGNPEEED
Upstream
Downstream
8 0
CTNNB1 (human)
K49-ac
CTNNB1 (mouse)
K49-ac
CTNNB1 (rat)
K49-ac
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
  • protein stabilization
Effects on Biological Processes:
  • carcinogenesis, inhibited
  • cell motility, induced
  • transcription, induced
Regulatory protein:
  • DBC1 (human)
CTNNB1 (human) TAPsLsGkGNPEEED K49-ac
CTNNB1 (mouse) TAPsLsGkGNPEEED K49-ac
CTNNB1 (rat) TAPsLSGKGNPEEED K49
K49-ub
TAPsLsGkGNPEEED
Downstream
1 0
Effects on Modified Protein
  • protein degradation
Effects on Biological Processes:
  • carcinogenesis, inhibited
  • cell growth, inhibited
  • transcription, inhibited
CTNNB1 (human) TAPsLsGkGNPEEED K49-ub
CTNNB1 (mouse) TAPsLsGKGNPEEED K49
CTNNB1 (rat) TAPsLSGKGNPEEED K49
K49-m3
TAPsLsGkGNPEEED
1 0
CTNNB1 (human) TAPsLsGkGNPEEED K49-m3
CTNNB1 (mouse) TAPsLsGKGNPEEED K49
CTNNB1 (rat) TAPsLSGKGNPEEED K49
Y64-p
VDTSQVLyEWEQGFS
Upstream
2 1
Kinase, in vitro:
  • Brk (human)
  • JAK3 (human)
Putative in vivo kinases:
  • Brk (mouse)
  • JAK3 (human)
CTNNB1 (human) VDTSQVLyEWEQGFS Y64-p
CTNNB1 (mouse) VDTSQVLYEWEQGFS Y64
CTNNB1 (rat) VDTSQVLYEWEQGFS Y64
S73-p
WEQGFSQsFTQEQVA
1 0
CTNNB1 (human) WEQGFSQsFTQEQVA S73-p
CTNNB1 (mouse) WEQGFSQSFTQEQVA S73
CTNNB1 (rat) WEQGFSQSFTQEQVA S73
Y86-p
VADIDGQyAMTRAQR
Upstream
Downstream
8 23
Effects on Modified Protein
  • molecular association, regulation
  • protein stabilization
Effects on Biological Processes:
  • cell growth, altered
  • transcription, altered
  • transcription, induced
Kinase, in vitro:
  • Abl (human)
  • JAK3 (human)
Putative in vivo kinases:
  • Abl (human)
  • JAK3 (human)
Putative upstream phosphatases:
  • SHP-1 (mouse)
Regulatory protein:
  • Src (human)
Treatment
  • imatinib
  • SB216763
  • SKI-606
  • Su11274
  • U0126
CTNNB1 (human) VADIDGQyAMTRAQR Y86-p
CTNNB1 (mouse) VADIDGQyAMTRAQR Y86-p
CTNNB1 (rat) VADIDGQYAMTRAQR Y86
T102-p
RAAMFPEtLDEGMQI
Upstream
Downstream
2 0
Effects on Modified Protein
  • protein degradation
Effects on Biological Processes:
  • cell motility, altered
Kinase, in vitro:
  • CK2A2 (human)
CTNNB1 (human) RAAMFPEtLDEGMQI T102-p
CTNNB1 (mouse) RAAMFPETLDEGMQI T102
CTNNB1 (rat) RAAMFPETLDEGMQI T102
T112-p
EGMQIPStQFdAAHP
Upstream
Downstream
2 0
Effects on Modified Protein
  • intracellular localization
  • protein degradation
Effects on Biological Processes:
  • cell growth, inhibited
  • cell motility, altered
  • cell motility, inhibited
  • transcription, induced
Kinase, in vitro:
  • CK2A2 (human)
  • PRKD1 (human)
Putative in vivo kinases:
  • PRKD1 (human)
CTNNB1 (human) EGMQIPStQFdAAHP T112-p
CTNNB1 (mouse) EGMQIPSTQFDAAHP T112
CTNNB1 (rat) EGMQIPSTQFDAAHP T112
D115-ca
QIPStQFdAAHPtNV
0 1
CTNNB1 (human) QIPStQFdAAHPtNV D115-ca
CTNNB1 (mouse) QIPSTQFDAAHPtNV D115
CTNNB1 (rat) QIPSTQFDAAHPTNV D115
T120-p
QFdAAHPtNVQRLAE
Upstream
Downstream
5 0
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
  • protein degradation
Effects on Biological Processes:
  • cell growth, inhibited
  • cell motility, inhibited
  • transcription, altered
  • transcription, induced
  • transcription, inhibited
Kinase, in vitro:
  • PRKD1 (human)
Putative in vivo kinases:
  • PRKD1 (human)
Treatment
  • CID755673
  • phosphorylated peptide
  • siRNA
CTNNB1 (human) QFdAAHPtNVQRLAE T120-p
CTNNB1 (mouse) QFDAAHPtNVQRLAE T120-p
CTNNB1 (rat) QFDAAHPTNVQRLAE T120
S129-p
VQRLAEPsQMLkHAV
0 1
CTNNB1 (human) VQRLAEPsQMLkHAV S129-p
CTNNB1 (mouse) VQRLAEPSQMLkHAV S129
CTNNB1 (rat) VQRLAEPSQMLKHAV S129
K133-ub
AEPsQMLkHAVVNLI
0 10
CTNNB1 (human) AEPsQMLkHAVVNLI K133-ub
CTNNB1 (mouse) AEPSQMLkHAVVNLI K133-ub
CTNNB1 (rat) AEPSQMLKHAVVNLI K133
Y142-p
AVVNLINyQDDAELA
Upstream
Downstream
15 2
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
  • protein degradation
Effects on Biological Processes:
  • apoptosis, inhibited
  • carcinogenesis, induced
  • cell growth, induced
  • signaling pathway regulation
Kinase, in vitro:
  • Brk (human)
  • EGFR (human)
  • FGFR2 (human)
  • FGFR3 (human)
  • TrkA (human)
Putative in vivo kinases:
  • EGFR (human)
  • FGFR2 (human)
  • FGFR3 (human)
  • TrkA (human)
Regulatory protein:
  • Fer (human)
  • Src (human)
Treatment
  • conditioned medium
  • CTGF
  • FGF2
  • HGF
  • imatinib
  • refametinib
  • SB216763
  • SKI-606
  • sorafenib
  • U0126
CTNNB1 (human) AVVNLINyQDDAELA Y142-p
CTNNB1 (mouse) AVVNLINyQDDAELA Y142-p
CTNNB1 (rat) AVVNLINyQDDAELA Y142-p
K158-ub
RAIPELTkLLNDEDQ
0 5
CTNNB1 (human) RAIPELTkLLNDEDQ K158-ub
CTNNB1 (mouse) RAIPELTkLLNDEDQ K158-ub
CTNNB1 (rat) RAIPELTKLLNDEDQ K158
K170-ub
EDQVVVNkAAVMVHQ
0 12
CTNNB1 (human) EDQVVVNkAAVMVHQ K170-ub
CTNNB1 (mouse) EDQVVVNkAAVMVHQ K170-ub
CTNNB1 (rat) EDQVVVNKAAVMVHQ K170
S179-p
AVMVHQLskKEASRH
0 5
CTNNB1 (human) AVMVHQLskKEASRH S179-p
CTNNB1 (mouse) AVMVHQLsKKEASRH S179-p
CTNNB1 (rat) AVMVHQLSKKEASRH S179
K180-ub
VMVHQLskKEASRHA
0 7
CTNNB1 (human) VMVHQLskKEASRHA K180-ub
CTNNB1 (mouse) VMVHQLsKKEASRHA K180
CTNNB1 (rat) VMVHQLSKKEASRHA K180
S191-p
SRHAIMRsPQMVsAI
Upstream
Downstream
4 55
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
  • protein conformation
  • protein stabilization
Effects on Biological Processes:
  • transcription, induced
Kinase, in vitro:
  • CDK5 (human)
Treatment
  • LRRK2-IN-1
CTNNB1 (human) SRHAIMRsPQMVsAI S191-p
CTNNB1 (mouse) SRHAIMRsPQMVSAI S191-p
CTNNB1 (rat) SRHAIMRsPQMVSAI S191-p
S196-p
MRsPQMVsAIVRTMQ
0 3
CTNNB1 (human) MRsPQMVsAIVRTMQ S196-p
CTNNB1 (mouse) MRsPQMVSAIVRTMQ S196
CTNNB1 (rat) MRsPQMVSAIVRTMQ S196
S222-p
AGTLHNLsHHREGLL
0 3
CTNNB1 (human) AGTLHNLsHHREGLL S222-p
CTNNB1 (mouse) AGTLHNLsHHREGLL S222-p
CTNNB1 (rat) AGTLHNLSHHREGLL S222
K233-ub
EGLLAIFkSGGIPAL
0 14
CTNNB1 (human) EGLLAIFkSGGIPAL K233-ub
CTNNB1 (mouse) EGLLAIFkSGGIPAL K233-ub
CTNNB1 (rat) EGLLAIFKSGGIPAL K233
S246-p
ALVKMLGsPVDSVLF
Upstream
Downstream
3 0
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
  • protein conformation
  • protein stabilization
Effects on Biological Processes:
  • transcription, induced
Kinase, in vitro:
  • CDK5 (human)
CTNNB1 (human) ALVKMLGsPVDSVLF S246-p
CTNNB1 (mouse) ALVKMLGSPVDSVLF S246
CTNNB1 (rat) ALVKMLGSPVDSVLF S246
K288-ub
KMVALLNkTNVKFLA
0 1
CTNNB1 (human) KMVALLNkTNVKFLA K288-ub
CTNNB1 (mouse) KMVALLNKTNVKFLA K288
CTNNB1 (rat) KMVALLNKTNVKFLA K288
Y331-p
LVNIMRTytyEkLLW
Upstream
1 2
Kinase, in vitro:
  • Brk (human)
Treatment
  • acetaldehyde
CTNNB1 (human) LVNIMRTytyEkLLW Y331-p
CTNNB1 (mouse) LVNIMRTYTYEKLLW Y331
CTNNB1 (rat) LVNIMRTYTYEKLLW Y331
T332-p
VNIMRTytyEkLLWT
Upstream
Downstream
1 0
Effects on Biological Processes:
  • apoptosis, induced
  • transcription, inhibited
Kinase, in vitro:
  • CAMK2A (human)
CTNNB1 (human) VNIMRTytyEkLLWT T332-p
CTNNB1 (mouse) VNIMRTYTYEKLLWT T332
CTNNB1 (rat) VNIMRTYTYEKLLWT T332
Y333-p
NIMRTytyEkLLWTT
Upstream
Downstream
3 2
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
Effects on Biological Processes:
  • carcinogenesis, induced
  • cell cycle regulation
  • cell growth, induced
  • transcription, induced
Kinase, in vitro:
  • Brk (human)
  • Src (human)
Putative in vivo kinases:
  • Src (human)
Regulatory protein:
  • FBXL7 (human)
Treatment
  • acetaldehyde
CTNNB1 (human) NIMRTytyEkLLWTT Y333-p
CTNNB1 (mouse) NIMRTYTYEKLLWTT Y333
CTNNB1 (rat) NIMRTYTYEKLLWTT Y333
K335-ub
MRTytyEkLLWTTSR
0 3
CTNNB1 (human) MRTytyEkLLWTTSR K335-ub
CTNNB1 (mouse) MRTYTYEKLLWTTSR K335
CTNNB1 (rat) MRTYTYEKLLWTTSR K335
K345-ac
WTTSRVLkVLSVCSS
Downstream
2 0
Effects on Modified Protein
  • activity, induced
  • molecular association, regulation
Effects on Biological Processes:
  • transcription, induced
CTNNB1 (human) WTTSRVLkVLSVCSS K345-ac
CTNNB1 (mouse) WTTSRVLKVLSVCSS K345
CTNNB1 (rat) WTTSRVLKVLSVCSS K345
K345-ub
WTTSRVLkVLSVCSS
0 2
CTNNB1 (human) WTTSRVLkVLSVCSS K345-ub
CTNNB1 (mouse) WTTSRVLKVLSVCSS K345
CTNNB1 (rat) WTTSRVLKVLSVCSS K345
K354-ub
LSVCSSNkPAIVEAG
0 8
CTNNB1 (human) LSVCSSNkPAIVEAG K354-ub
CTNNB1 (mouse) LSVCSSNKPAIVEAG K354
CTNNB1 (rat) LSVCSSNKPAIVEAG K354
K354-ac
LSVCSSNkPAIVEAG
Upstream
Downstream
1 0
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
Effects on Biological Processes:
  • transcription, induced
Treatment
  • C646
  • glucose
  • lithium
  • nicotinamide
  • resveratrol
CTNNB1 (human) LSVCSSNkPAIVEAG K354-ac
CTNNB1 (mouse) LSVCSSNKPAIVEAG K354
CTNNB1 (rat) LSVCSSNKPAIVEAG K354
T393-p
RNLSDAAtkQEGMEG
Upstream
Downstream
2 0
Effects on Modified Protein
  • activity, induced
  • molecular association, regulation
  • phosphorylation
  • protein stabilization
Effects on Biological Processes:
  • transcription, altered
  • transcription, induced
Kinase, in vitro:
  • CK2A1 (mouse)
Treatment
  • apigenin
  • wortmannin
CTNNB1 (human) RNLSDAAtkQEGMEG T393-p
CTNNB1 (mouse) RNLSDAAtKQEGMEG T393-p
CTNNB1 (rat) RNLSDAATKQEGMEG T393
K394-ub
NLSDAAtkQEGMEGL
Downstream
1 0
Effects on Modified Protein
  • protein stabilization
Effects on Biological Processes:
  • transcription, induced
CTNNB1 (human) NLSDAAtkQEGMEGL K394-ub
CTNNB1 (mouse) NLSDAAtKQEGMEGL K394
CTNNB1 (rat) NLSDAATKQEGMEGL K394
K435-ac
TCNNYKNkMMVCQVG
0 1
CTNNB1 (human) TCNNYKNkMMVCQVG K435-ac
CTNNB1 (mouse) TCNNYKNKMMVCQVG K435
CTNNB1 (rat) TCNNYKNKMMVCQVG K435
K435-ub
TCNNYKNkMMVCQVG
0 8
CTNNB1 (human) TCNNYKNkMMVCQVG K435-ub
CTNNB1 (mouse) TCNNYKNKMMVCQVG K435
CTNNB1 (rat) TCNNYKNKMMVCQVG K435
T461-p
AGDREDItEPAICAL
0 1
CTNNB1 (human) AGDREDItEPAICAL T461-p
CTNNB1 (mouse) AGDREDItEPAICAL T461-p
CTNNB1 (rat) AGDREDITEPAICAL T461
T472-p
ICALRHLtsRHQEAE
Upstream
Downstream
1 1
Effects on Biological Processes:
  • apoptosis, induced
  • transcription, inhibited
Kinase, in vitro:
  • CAMK2A (human)
CTNNB1 (human) ICALRHLtsRHQEAE T472-p
CTNNB1 (mouse) ICALRHLTSRHQEAE T472
CTNNB1 (rat) ICALRHLTSRHQEAE T472
S473-p
CALRHLtsRHQEAEM
0 1
CTNNB1 (human) CALRHLtsRHQEAEM S473-p
CTNNB1 (mouse) CALRHLTSRHQEAEM S473
CTNNB1 (rat) CALRHLTSRHQEAEM S473
Y489-p
QNAVRLHyGLPVVVk
Upstream
Downstream
2 98
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
Effects on Biological Processes:
  • transcription, induced
Kinase, in vitro:
  • Abl (human)
CTNNB1 (human) QNAVRLHyGLPVVVk Y489-p
CTNNB1 (mouse) QNAVRLHyGLPVVVK Y489-p
CTNNB1 (rat) QNAVRLHyGLPVVVK Y489-p
K496-ub
yGLPVVVkLLHPPSH
0 1
CTNNB1 (human) yGLPVVVkLLHPPSH K496-ub
CTNNB1 (mouse) yGLPVVVKLLHPPSH K496
CTNNB1 (rat) yGLPVVVKLLHPPSH K496
K508-ub
PSHWPLIkAtVGLIR
0 32
CTNNB1 (human) PSHWPLIkAtVGLIR K508-ub
CTNNB1 (mouse) PSHWPLIKATVGLIR K508
CTNNB1 (rat) PSHWPLIKATVGLIR K508
T510-p
HWPLIkAtVGLIRNL
0 1
CTNNB1 (human) HWPLIkAtVGLIRNL T510-p
CTNNB1 (mouse) HWPLIKATVGLIRNL T510
CTNNB1 (rat) HWPLIKATVGLIRNL T510
T547-p
LVRAHQDtQRRtsMG
0 2
CTNNB1 (human) LVRAHQDtQRRtsMG T547-p
CTNNB1 (mouse) LVRAHQDTQRRtsMG T547
CTNNB1 (rat) LVRAHQDTQRRtsMG T547
T551-p
HQDtQRRtsMGGtQQ
1 20
CTNNB1 (human) HQDtQRRtsMGGtQQ T551-p
CTNNB1 (mouse) HQDTQRRtsMGGtQQ T551-p
CTNNB1 (rat) HQDTQRRtsMGGTQQ T551-p
S552-p
QDtQRRtsMGGtQQQ
Upstream
Downstream
22 68
CTNNB1 (human)
S552-p
CTNNB1 (mouse)
S552-p
CTNNB1 (rat)
S552-p
Effects on Modified Protein
  • intracellular localization
Effects on Biological Processes:
  • apoptosis, induced
  • cell motility, altered
  • cytoskeletal reorganization
  • transcription, induced
  • transcription, inhibited
Kinase, in vitro:
  • Akt1 (human)
  • Akt2 (human)
  • CAMK2A (human)
  • PKACA (human)
Putative in vivo kinases:
  • Akt1 (human)
  • Akt2 (human)
  • PAK1 (human)
Regulatory protein:
  • ARFGEF1 (human)
  • ARFGEF2 (human)
  • CaR (human)
  • Merlin (human)
  • PKACA (human)
  • SFRP2 (human)
Treatment
  • angiotensin_2
  • Ca(2+)
  • colforsin
  • EGF
  • ESI-09
  • exenatide
  • Exendin-3
  • GLP-1
  • glucose
  • GSK690693
  • H-89
  • IFN-gamma
  • IPA-3
  • KT5720
  • LY294002
  • microparticles
  • NSC23766
  • siRNA
  • tecalcet
  • TNF
  • U0126
CTNNB1 (human) QDtQRRtsMGGtQQQ S552-p
CTNNB1 (mouse) QDTQRRtsMGGtQQQ S552-p
CTNNB1 (rat) QDTQRRtsMGGTQQQ S552-p
T556-p
RRtsMGGtQQQFVEG
Downstream
1 26
Effects on Modified Protein
  • intracellular localization
Effects on Biological Processes:
  • signaling pathway regulation
  • transcription, inhibited
CTNNB1 (human) RRtsMGGtQQQFVEG T556-p
CTNNB1 (mouse) RRtsMGGtQQQFVEG T556-p
CTNNB1 (rat) RRtsMGGTQQQFVEG T556
T574-p
EEIVEGCtGALHILA
0 2
CTNNB1 (human) EEIVEGCtGALHILA T574-p
CTNNB1 (mouse) EEIVEGCTGALHILA T574
CTNNB1 (rat) EEIVEGCTGALHILA T574
S605-p
LFVQLLYsPIENIQR
Upstream
Downstream
3 0
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
  • protein conformation
  • protein stabilization
Effects on Biological Processes:
  • cell growth, induced
  • transcription, induced
Kinase, in vitro:
  • P38G (human)
Putative in vivo kinases:
  • P38G (human)
CTNNB1 (human) LFVQLLYsPIENIQR S605-p
CTNNB1 (mouse) LFVQLLYsPIENIQR S605-p
CTNNB1 (rat) LFVQLLYSPIENIQR S605
K625-ub
LCELAQDkEAAEAIE
0 6
CTNNB1 (human) LCELAQDkEAAEAIE K625-ub
CTNNB1 (mouse) LCELAQDkEAAEAIE K625-ub
CTNNB1 (rat) LCELAQDKEAAEAIE K625
S646-p
PLTELLHsRNEGVAt
Downstream
1 0
Effects on Modified Protein
  • intracellular localization
CTNNB1 (human) PLTELLHsRNEGVAt S646-p
CTNNB1 (mouse) PLTELLHSRNEGVAT S646
CTNNB1 (rat) PLTELLHSRNEGVAT S646
T653-p
sRNEGVAtyAAAVLF
0 1
CTNNB1 (human) sRNEGVAtyAAAVLF T653-p
CTNNB1 (mouse) SRNEGVATyAAAVLF T653
CTNNB1 (rat) SRNEGVATyAAAVLF T653
Y654-p
RNEGVAtyAAAVLFR
Upstream
Downstream
26 21
Effects on Modified Protein
  • activity, induced
  • intracellular localization
  • molecular association, regulation
  • protein stabilization
Effects on Biological Processes:
  • cell growth, altered
  • cell growth, induced
  • cytoskeletal reorganization
  • transcription, altered
  • transcription, induced
Kinase, in vitro:
  • Abl (human)
  • EGFR (human)
  • HER2 (human)
Putative in vivo kinases:
  • Abl (human)
  • Src (human)
Putative upstream phosphatases:
  • SHP-1 (mouse)
Regulatory protein:
  • FBXL7 (human)
  • Src (human)
Treatment
  • 5-aza-CdR
  • acetaldehyde
  • HGF
  • hydroxyflutamide
  • imatinib
  • SB216763
  • SKI-606
  • testosterone
  • U0126
  • wortmannin
CTNNB1 (human) RNEGVAtyAAAVLFR Y654-p
CTNNB1 (mouse) RNEGVATyAAAVLFR Y654-p
CTNNB1 (rat) RNEGVATyAAAVLFR Y654-p
Y670-p
SEDKPQDykKRLsVE
Upstream
Downstream
2 16
Effects on Modified Protein
  • activity, induced
  • intracellular localization
  • molecular association, regulation
Effects on Biological Processes:
  • cell growth, altered
  • cell growth, induced
  • transcription, induced
Treatment
  • acetaldehyde
  • HGF
CTNNB1 (human) SEDKPQDykKRLsVE Y670-p
CTNNB1 (mouse) SEDKPQDYkKRLsVE Y670
CTNNB1 (rat) SEDKPQDYKKRLsVE Y670
K671-ub
EDKPQDykKRLsVEL
0 5
CTNNB1 (human) EDKPQDykKRLsVEL K671-ub
CTNNB1 (mouse) EDKPQDYkKRLsVEL K671-ub
CTNNB1 (rat) EDKPQDYKKRLsVEL K671
S675-p
QDykKRLsVELtsSL
Upstream
Downstream
24 70
CTNNB1 (human)
S675-p
CTNNB1 (mouse)
S675-p
CTNNB1 (rat)
S675-p
Effects on Modified Protein
  • activity, induced
  • intracellular localization
  • molecular association, regulation
  • protein stabilization
Effects on Biological Processes:
  • transcription, induced
Kinase, in vitro:
  • MEKK2 (human)
  • PAK1 (human)
  • PAK4 (human)
  • PKACA (human)
Putative in vivo kinases:
  • PAK1 (human)
  • PAK4 (human)
  • PKACA (human)
Regulatory protein:
  • ARFGEF1 (human)
  • ARFGEF2 (human)
  • CaR (human)
  • GSKIP (human)
  • Merlin (human)
  • PAK2 (human)
  • RAC1 (human)
  • SFRP2 (human)
Treatment
  • Ca(2+)
  • cAMP_analog
  • colforsin
  • EGF
  • H-89
  • IPA-3
  • LRRK2-IN-1
  • microparticles
  • nocodazole
  • NSC23766
  • PKI
  • siRNA
  • tecalcet
  • Wnt
CTNNB1 (human) QDykKRLsVELtsSL S675-p
CTNNB1 (mouse) QDYkKRLsVELtSsL S675-p
CTNNB1 (rat) QDYKKRLsVELTSSL S675-p
T679-p
KRLsVELtsSLFRTE
0 3
CTNNB1 (human) KRLsVELtsSLFRTE T679-p
CTNNB1 (mouse) KRLsVELtSsLFRtE T679-p
CTNNB1 (rat) KRLsVELTSSLFRTE T679
S680-p
RLsVELtsSLFRTEP
0 1
CTNNB1 (human) RLsVELtsSLFRTEP S680-p
CTNNB1 (mouse) RLsVELtSsLFRtEP S680
CTNNB1 (rat) RLsVELTSSLFRTEP S680
S681
LsVELtsSLFRTEPM
0 1
CTNNB1 (human) LsVELtsSLFRTEPM S681
CTNNB1 (mouse) LsVELtSsLFRtEPM S681-p
CTNNB1 (rat) LsVELTSSLFRTEPM S681
T685
LtsSLFRTEPMAWNE
0 1
CTNNB1 (human) LtsSLFRTEPMAWNE T685
CTNNB1 (mouse) LtSsLFRtEPMAWNE T685-p
CTNNB1 (rat) LTSSLFRTEPMAWNE T685
T693
EPMAWNETADLGLDI
0 1
CTNNB1 (human) EPMAWNETADLGLDI T693
CTNNB1 (mouse) EPMAWNEtADLGLDI T693-p
CTNNB1 (rat) EPMAWNETADLGLDI T693
S715-p
GYRQDDPsyRsFHsG
Upstream
Downstream
1 1
Effects on Modified Protein
  • molecular association, regulation
  • protein degradation
Kinase, in vitro:
  • PKCD (human)
Putative in vivo kinases:
  • PKCD (human)
CTNNB1 (human) GYRQDDPsyRsFHsG S715-p
CTNNB1 (mouse) GYRQDDPSYRSFHSG S715
CTNNB1 (rat) GYRQDDPSYRSFHSG S715
Y716-p
YRQDDPsyRsFHsGG
Upstream
0 40
Treatment
  • gefitinib
  • Su11274
CTNNB1 (human) YRQDDPsyRsFHsGG Y716-p
CTNNB1 (mouse) YRQDDPSYRSFHSGG Y716
CTNNB1 (rat) YRQDDPSYRSFHSGG Y716
S718-p
QDDPsyRsFHsGGyG
Upstream
1 4
Kinase, in vitro:
  • PLK1 (human)
Putative in vivo kinases:
  • PLK1 (human)
Treatment
  • doxycycline
  • nocodazole
CTNNB1 (human) QDDPsyRsFHsGGyG S718-p
CTNNB1 (mouse) QDDPSYRSFHSGGYG S718
CTNNB1 (rat) QDDPSYRSFHSGGYG S718
S721-p
PsyRsFHsGGyGQDA
0 2
CTNNB1 (human) PsyRsFHsGGyGQDA S721-p
CTNNB1 (mouse) PSYRSFHSGGYGQDA S721
CTNNB1 (rat) PSYRSFHSGGYGQDA S721
Y724-p
RsFHsGGyGQDALGM
0 1
CTNNB1 (human) RsFHsGGyGQDALGM Y724-p
CTNNB1 (mouse) RSFHSGGYGQDALGM Y724
CTNNB1 (rat) RSFHSGGYGQDALGM Y724
Y748-p
GHHPGADyPVDGLPD
0 1
CTNNB1 (human) GHHPGADyPVDGLPD Y748-p
CTNNB1 (mouse) GHHPGADYPVDGLPD Y748
CTNNB1 (rat) GHHPGADYPVDGLPD Y748
K133-m1
AEPsQMLkHAVVNLI
1 0
CTNNB1 (human) AEPsQMLkHAVVNLI K133-m1
CTNNB1 (mouse) under review -
CTNNB1 (rat) under review -