Other Species / Isoforms
  SQSTM1 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

  HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
K378-ac
QEGPtGLkEAALyPH
0 2
SQSTM1 (human) QEGPtGLkEAALyPH K378-ac
SQSTM1 iso2 (human) QEGPTGLKEAALYPH K294
SQSTM1 (mouse) QEGPTGLKEAALYPH K380
SQSTM1 iso2 (mouse) gap -
SQSTM1 (rat) QEGPTGLKEAALYPH K377
SQSTM1 iso2 (rat) QEGPTGLKEAALYPH K350
SQSTM1 iso3 (rat) gap -
K264-ub
IDVEHGGkRsRLtPV
0 25
SQSTM1 (human) IDVEHGGkRsRLtPV K264-ub
SQSTM1 iso2 (human) IDVEHGGKRSRLTPV K180
SQSTM1 (mouse) IDVEHGGKRsRLtPt K264
SQSTM1 iso2 (mouse) IDVEHGGKRSRLTPT K264
SQSTM1 (rat) IDVEHGGKRSRLtPT K261
SQSTM1 iso2 (rat) IDVEHGGKRSRLTPT K234
SQSTM1 iso3 (rat) gap -
K281-ub
EssstEEksSsQPss
1 4
SQSTM1 (human) EssstEEksSsQPss K281-ub
SQSTM1 iso2 (human) ESSSTEEKSSSQPSS K197
SQSTM1 (mouse) sstGTEDKSNtQPSS K283
SQSTM1 iso2 (mouse) SSTGTEDKSNTQPSS K283
SQSTM1 (rat) SSTGTEDKSGTQPSS K280
SQSTM1 iso2 (rat) SSTGTEDKSGTQPSS K253
SQSTM1 iso3 (rat) gap -
K313-ub
sLAEQMRkIALEsEG
0 19
SQSTM1 (human) sLAEQMRkIALEsEG K313-ub
SQSTM1 iso2 (human) SLAEQMRKIALESEG K229
SQSTM1 (mouse) sLTEQMkkIALEsVG K315-ub
SQSTM1 iso2 (mouse) SLTEQMKKIALESVG K315
SQSTM1 (rat) sLTEQMKKIALESVG K312
SQSTM1 iso2 (rat) SLTEQMKKIALESVG K285
SQSTM1 iso3 (rat) gap -
S370-p
GPssLDPsQEGPtGL
0 10
SQSTM1 (human) GPssLDPsQEGPtGL S370-p
SQSTM1 iso2 (human) GPSSLDPSQEGPTGL S286
SQSTM1 (mouse) GPssLDPsQEGPTGL S372-p
SQSTM1 iso2 (mouse) gap -
SQSTM1 (rat) GPSsLDPSQEGPTGL S369
SQSTM1 iso2 (rat) GPSSLDPSQEGPTGL S342
SQSTM1 iso3 (rat) gap -
K420-ac
LTRLLQTkNYDIGAA
Downstream
1 1
Effects on Modified Protein
  • molecular association, regulation
SQSTM1 (human) LTRLLQTkNYDIGAA K420-ac
SQSTM1 iso2 (human) LTRLLQTKNYDIGAA K336
SQSTM1 (mouse) LTRLLQTKNYDIGAA K422
SQSTM1 iso2 (mouse) LTRLLQTKNYDIGAA K384
SQSTM1 (rat) LTRLLQTKNYDIGAA K419
SQSTM1 iso2 (rat) LTRLLQTKNYDIGAA K392
SQSTM1 iso3 (rat) gap -
K7-ub
_MASLTVkAyLLGkE
Downstream
3 0
Effects on Modified Protein
  • activity, induced
  • molecular association, regulation
  • protein degradation
Effects on Biological Processes:
  • autophagy, induced
SQSTM1 (human) _MASLTVkAyLLGkE K7-ub
SQSTM1 iso2 (human) gap -
SQSTM1 (mouse) _MASFTVKAYLLGkE K7
SQSTM1 iso2 (mouse) _MASFTVKAYLLGKE K7
SQSTM1 (rat) _MASLTVKAYLLGKE K7
SQSTM1 iso2 (rat) _MASLTVKAYLLGKE K7
SQSTM1 iso3 (rat) _MASLTVKAYLLGKE K7
Y9-p
ASLTVkAyLLGkEDA
0 2
SQSTM1 (human) ASLTVkAyLLGkEDA Y9-p
SQSTM1 iso2 (human) gap -
SQSTM1 (mouse) ASFTVKAYLLGkEEA Y9
SQSTM1 iso2 (mouse) ASFTVKAYLLGKEEA Y9
SQSTM1 (rat) ASLTVKAYLLGKEEA Y9
SQSTM1 iso2 (rat) ASLTVKAYLLGKEEA Y9
SQSTM1 iso3 (rat) ASLTVKAYLLGKEEA Y9
K13-ac
VkAyLLGkEDAAREI
0 1
SQSTM1 (human) VkAyLLGkEDAAREI K13-ac
SQSTM1 iso2 (human) gap -
SQSTM1 (mouse) VKAYLLGKEEATREI K13
SQSTM1 iso2 (mouse) VKAYLLGKEEATREI K13
SQSTM1 (rat) VKAYLLGKEEAAREI K13
SQSTM1 iso2 (rat) VKAYLLGKEEAAREI K13
SQSTM1 iso3 (rat) VKAYLLGKEEAAREI K13
K13-ub
VkAyLLGkEDAAREI
Downstream
2 56
Effects on Modified Protein
  • protein degradation
SQSTM1 (human) VkAyLLGkEDAAREI K13-ub
SQSTM1 iso2 (human) gap -
SQSTM1 (mouse) VKAYLLGkEEATREI K13-ub
SQSTM1 iso2 (mouse) VKAYLLGKEEATREI K13
SQSTM1 (rat) VKAYLLGKEEAAREI K13
SQSTM1 iso2 (rat) VKAYLLGKEEAAREI K13
SQSTM1 iso3 (rat) VKAYLLGKEEAAREI K13
S24-p
AREIRRFsFCCsPEP
Upstream
0 88
Treatment
  • bafilomycin_A
  • MG132
SQSTM1 (human) AREIRRFsFCCsPEP S24-p
SQSTM1 iso2 (human) gap -
SQSTM1 (mouse) TREIRRFsFCFsPEP S24-p
SQSTM1 iso2 (mouse) TREIRRFSFCFSPEP S24
SQSTM1 (rat) AREIRRFsFCFSPEP S24-p
SQSTM1 iso2 (rat) AREIRRFSFCFSPEP S24
SQSTM1 iso3 (rat) AREIRRFSFCFSPEP S24
S28-p
RRFsFCCsPEPEAEA
Upstream
Downstream
1 17
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
  • protein degradation
  • ubiquitination
Effects on Biological Processes:
  • apoptosis, inhibited
  • autophagy, induced
  • carcinogenesis, induced
  • cell growth, induced
  • transcription, induced
Regulatory protein:
  • AMPKA1 (human)
  • AMPKA2 (human)
  • KHK (human)
  • PINK1 (human)
view more >
Treatment
  • A769662
  • amino_acids
  • compound_C
  • H2O2
  • hypoxia
  • MG132
  • NAC
  • siRNA
view more >
SQSTM1 (human) RRFsFCCsPEPEAEA S28-p
SQSTM1 iso2 (human) gap -
SQSTM1 (mouse) RRFsFCFsPEPEAEA S28-p
SQSTM1 iso2 (mouse) RRFSFCFSPEPEAEA S28
SQSTM1 (rat) RRFsFCFSPEPEAEA S28
SQSTM1 iso2 (rat) RRFSFCFSPEPEAEA S28
SQSTM1 iso3 (rat) RRFSFCFSPEPEAEA S28
S49-p
GPCERLLsRVAALFP
0 2
SQSTM1 (human) GPCERLLsRVAALFP S49-p
SQSTM1 iso2 (human) gap -
SQSTM1 (mouse) GPCERLLSRVAVLFP S49
SQSTM1 iso2 (mouse) GPCERLLSRVAVLFP S49
SQSTM1 (rat) GPCERLLSRVAVLFP S47
SQSTM1 iso2 (rat) GPCERLLSRVAVLFP S47
SQSTM1 iso3 (rat) GPCERLLSRVAVLFP S47
Y67-p
PGGFQAHyRDEDGDL
0 2
SQSTM1 (human) PGGFQAHyRDEDGDL Y67-p
SQSTM1 iso2 (human) gap -
SQSTM1 (mouse) PGGFQAHYRDEDGDL Y67
SQSTM1 iso2 (mouse) PGGFQAHYRDEDGDL Y67
SQSTM1 (rat) PGGFQAHYRDEDGDL Y65
SQSTM1 iso2 (rat) PGGFQAHYRDEDGDL Y65
SQSTM1 iso3 (rat) PGGFQAHYRDEDGDL Y65
K91-ub
TMAMSYVkDDIFRIY
Upstream
Downstream
1 31
Effects on Biological Processes:
  • autophagy, induced
Regulatory protein:
  • RNF166 (human)
SQSTM1 (human) TMAMSYVkDDIFRIY K91-ub
SQSTM1 iso2 (human) _MAMSYVKDDIFRIY K7
SQSTM1 (mouse) TMAMSYVkDDIFRIY K91-ub
SQSTM1 iso2 (mouse) TMAMSYVKDDIFRIY K91
SQSTM1 (rat) TMAMSYVKDDIFRIY K89
SQSTM1 iso2 (rat) TMAMSYVKDDIFRIY K89
SQSTM1 iso3 (rat) TMAMSYVKDDIFRIY K89
T138-p
CNGPVVGtRYkCsVC
Upstream
Downstream
1 1
Effects on Biological Processes:
  • apoptosis, induced
Kinase, in vitro:
  • LRRK2 (human)
Putative in vivo kinases:
  • LRRK2 (human)
SQSTM1 (human) CNGPVVGtRYkCsVC T138-p
SQSTM1 iso2 (human) CNGPVVGTRYKCSVC T54
SQSTM1 (mouse) CNGPVVGTRYkCSVC T138
SQSTM1 iso2 (mouse) CNGPVVGTRYKCSVC T138
SQSTM1 (rat) CNGPVVGTRYKCSVC T135
SQSTM1 iso2 (rat) CNGPVVGTRYKCSVC T135
SQSTM1 iso3 (rat) CNGPVVGTRYKCSVC T135
K141-ub
PVVGtRYkCsVCPDy
0 39
SQSTM1 (human) PVVGtRYkCsVCPDy K141-ub
SQSTM1 iso2 (human) PVVGTRYKCSVCPDY K57
SQSTM1 (mouse) PVVGTRYkCSVCPDy K141-ub
SQSTM1 iso2 (mouse) PVVGTRYKCSVCPDY K141
SQSTM1 (rat) PVVGTRYKCSVCPDY K138
SQSTM1 iso2 (rat) PVVGTRYKCSVCPDY K138
SQSTM1 iso3 (rat) PVVGTRYKCSVCPDY K138
S143-p
VGtRYkCsVCPDyDL
0 1
SQSTM1 (human) VGtRYkCsVCPDyDL S143-p
SQSTM1 iso2 (human) VGTRYKCSVCPDYDL S59
SQSTM1 (mouse) VGTRYkCSVCPDyDL S143
SQSTM1 iso2 (mouse) VGTRYKCSVCPDYDL S143
SQSTM1 (rat) VGTRYKCSVCPDYDL S140
SQSTM1 iso2 (rat) VGTRYKCSVCPDYDL S140
SQSTM1 iso3 (rat) VGTRYKCSVCPDYDL S140
Y148-p
kCsVCPDyDLCsVCE
0 46
SQSTM1 (human) kCsVCPDyDLCsVCE Y148-p
SQSTM1 iso2 (human) KCSVCPDYDLCSVCE Y64
SQSTM1 (mouse) kCSVCPDyDLCsVCE Y148-p
SQSTM1 iso2 (mouse) KCSVCPDYDLCSVCE Y148
SQSTM1 (rat) KCSVCPDYDLCSVCE Y145
SQSTM1 iso2 (rat) KCSVCPDYDLCSVCE Y145
SQSTM1 iso3 (rat) KCSVCPDYDLCSVCE Y145
S152-p
CPDyDLCsVCEGkGL
Upstream
0 10
Regulatory protein:
  • SMARCA4 (human)
SQSTM1 (human) CPDyDLCsVCEGkGL S152-p
SQSTM1 iso2 (human) CPDYDLCSVCEGKGL S68
SQSTM1 (mouse) CPDyDLCsVCEGkGL S152-p
SQSTM1 iso2 (mouse) CPDYDLCSVCEGKGL S152
SQSTM1 (rat) CPDYDLCSVCEGKGL S149
SQSTM1 iso2 (rat) CPDYDLCSVCEGKGL S149
SQSTM1 iso3 (rat) CPDYDLCSVCEGKGL S149
K157-ub
LCsVCEGkGLHRGHT
0 70
SQSTM1 (human) LCsVCEGkGLHRGHT K157-ub
SQSTM1 iso2 (human) LCSVCEGKGLHRGHT K73
SQSTM1 (mouse) LCsVCEGkGLHREHS K157-ub
SQSTM1 iso2 (mouse) LCSVCEGKGLHREHS K157
SQSTM1 (rat) LCSVCEGKGLHREHS K154
SQSTM1 iso2 (rat) LCSVCEGKGLHREHS K154
SQSTM1 iso3 (rat) LCSVCEGKGLHREHS K154
K165-ub
GLHRGHTkLAFPsPF
0 29
SQSTM1 (human) GLHRGHTkLAFPsPF K165-ub
SQSTM1 iso2 (human) GLHRGHTKLAFPSPF K81
SQSTM1 (mouse) GLHREHSkLIFPNPF K165-ub
SQSTM1 iso2 (mouse) GLHREHSKLIFPNPF K165
SQSTM1 (rat) GLHREHSKLIFPNPF K162
SQSTM1 iso2 (rat) GLHREHSKLIFPNPF K162
SQSTM1 iso3 (rat) GLHREHSKLIFPNPF K162
S170-p
HTkLAFPsPFGHLsE
Upstream
0 12
Treatment
  • nocodazole
SQSTM1 (human) HTkLAFPsPFGHLsE S170-p
SQSTM1 iso2 (human) HTKLAFPSPFGHLSE S86
SQSTM1 (mouse) HSkLIFPNPFGHLSD N170
SQSTM1 iso2 (mouse) HSKLIFPNPFGHLSD N170
SQSTM1 (rat) HSKLIFPNPFGHLSD N167
SQSTM1 iso2 (rat) HSKLIFPNPFGHLSD N167
SQSTM1 iso3 (rat) HSKLIFPNPFGHLSD N167
S176-p
PsPFGHLsEGFSHsr
0 7
SQSTM1 (human) PsPFGHLsEGFSHsr S176-p
SQSTM1 iso2 (human) PSPFGHLSEGFSHSR S92
SQSTM1 (mouse) PNPFGHLSDsFSHSR S176
SQSTM1 iso2 (mouse) PNPFGHLSDSFSHSR S176
SQSTM1 (rat) PNPFGHLSDSFSHSR S173
SQSTM1 iso2 (rat) PNPFGHLSDSFSHSR S173
SQSTM1 iso3 (rat) PNPFGHLSDSFSHSR S173
G178
PFGHLsEGFSHsrWL
0 5
SQSTM1 (human) PFGHLsEGFSHsrWL G178
SQSTM1 iso2 (human) PFGHLSEGFSHSRWL G94
SQSTM1 (mouse) PFGHLSDsFSHSRWL S178-p
SQSTM1 iso2 (mouse) PFGHLSDSFSHSRWL S178
SQSTM1 (rat) PFGHLSDSFSHSRWL S175
SQSTM1 iso2 (rat) PFGHLSDSFSHSRWL S175
SQSTM1 iso3 (rat) PFGHLSDSFSHSRWL S175
S182-p
LsEGFSHsrWLRkVk
0 3
SQSTM1 (human) LsEGFSHsrWLRkVk S182-p
SQSTM1 iso2 (human) LSEGFSHSRWLRKVK S98
SQSTM1 (mouse) LSDsFSHSRWLRKLK S182
SQSTM1 iso2 (mouse) LSDSFSHSRWLRKLK S182
SQSTM1 (rat) LSDSFSHSRWLRKLK S179
SQSTM1 iso2 (rat) LSDSFSHSRWLRKLK S179
SQSTM1 iso3 (rat) LSDSFSHSRWLRKLK S179
R183-m1
sEGFSHsrWLRkVkH
0 2
SQSTM1 (human) sEGFSHsrWLRkVkH R183-m1
SQSTM1 iso2 (human) SEGFSHSRWLRKVKH R99
SQSTM1 (mouse) SDsFSHSRWLRKLKH R183
SQSTM1 iso2 (mouse) SDSFSHSRWLRKLKH R183
SQSTM1 (rat) SDSFSHSRWLRKLKH R180
SQSTM1 iso2 (rat) SDSFSHSRWLRKLKH R180
SQSTM1 iso3 (rat) SDSFSHSRWLRKLKH R180
K187-ub
SHsrWLRkVkHGHFG
0 5
SQSTM1 (human) SHsrWLRkVkHGHFG K187-ub
SQSTM1 iso2 (human) SHSRWLRKVKHGHFG K103
SQSTM1 (mouse) SHSRWLRKLKHGHFG K187
SQSTM1 iso2 (mouse) SHSRWLRKLKHGHFG K187
SQSTM1 (rat) SHSRWLRKLKHGHFG K184
SQSTM1 iso2 (rat) SHSRWLRKLKHGHFG K184
SQSTM1 iso3 (rat) SHSRWLRKLKHGHFG K184
K189-ub
srWLRkVkHGHFGWP
Upstream
Downstream
1 14
Effects on Biological Processes:
  • autophagy, induced
Regulatory protein:
  • RNF166 (human)
SQSTM1 (human) srWLRkVkHGHFGWP K189-ub
SQSTM1 iso2 (human) SRWLRKVKHGHFGWP K105
SQSTM1 (mouse) SRWLRKLKHGHFGWP K189
SQSTM1 iso2 (mouse) SRWLRKLKHGHFGWP K189
SQSTM1 (rat) SRWLRKLKHGHFGWP K186
SQSTM1 iso2 (rat) SRWLRKLKHGHFGWP K186
SQSTM1 iso3 (rat) SRWLRKLKHGHFGWP K186
S207-p
MGPPGNWsPrPPRAG
Upstream
0 25
Treatment
  • BI_4834
  • MG132
  • nocodazole
view more >
SQSTM1 (human) MGPPGNWsPrPPRAG S207-p
SQSTM1 iso2 (human) MGPPGNWSPRPPRAG S123
SQSTM1 (mouse) MGPPGNWsPRPPRAG S207-p
SQSTM1 iso2 (mouse) MGPPGNWSPRPPRAG S207
SQSTM1 (rat) MGPPGNWSPRPPRAG S204
SQSTM1 iso2 (rat) MGPPGNWSPRPPRAG S204
SQSTM1 iso3 (rat) MGPPGNWSPRPPRAG S204
R209-m1
PPGNWsPrPPRAGEA
0 1
SQSTM1 (human) PPGNWsPrPPRAGEA R209-m1
SQSTM1 iso2 (human) PPGNWSPRPPRAGEA R125
SQSTM1 (mouse) PPGNWsPRPPRAGDG R209
SQSTM1 iso2 (mouse) PPGNWSPRPPRAGDG R209
SQSTM1 (rat) PPGNWSPRPPRAGDG R206
SQSTM1 iso2 (rat) PPGNWSPRPPRAGDG R206
SQSTM1 iso3 (rat) PPGNWSPRPPRAGDG R206
T221-p
GEARPGPtAEsAsGP
Upstream
0 1
Treatment
  • amino_acids
SQSTM1 (human) GEARPGPtAEsAsGP T221-p
SQSTM1 iso2 (human) GEARPGPTAESASGP T137
SQSTM1 (mouse) GDGRPCPTAESAsAP T221
SQSTM1 iso2 (mouse) GDGRPCPTAESASAP T221
SQSTM1 (rat) GDGRPCPTAESASAP T218
SQSTM1 iso2 (rat) GDGRPCPTAESGIEV T218
SQSTM1 iso3 (rat) GDGRPCPTAESGKAG T218
S224-p
RPGPtAEsAsGPSED
Upstream
0 3
Regulatory protein:
  • SMARCA4 (human)
Treatment
  • amino_acids
SQSTM1 (human) RPGPtAEsAsGPSED S224-p
SQSTM1 iso2 (human) RPGPTAESASGPSED S140
SQSTM1 (mouse) RPCPTAESAsAPPED S224
SQSTM1 iso2 (mouse) RPCPTAESASAPPED S224
SQSTM1 (rat) RPCPTAESASAPSED S221
SQSTM1 iso2 (rat) RPCPTAESGIEVDID S221
SQSTM1 iso3 (rat) RPCPTAESGKAGVCT S221
S226-p
GPtAEsAsGPSEDPs
Upstream
0 4
Treatment
  • nocodazole
SQSTM1 (human) GPtAEsAsGPSEDPs S226-p
SQSTM1 iso2 (human) GPTAESASGPSEDPS S142
SQSTM1 (mouse) CPTAESAsAPPEDPN S226-p
SQSTM1 iso2 (mouse) CPTAESASAPPEDPN S226
SQSTM1 (rat) CPTAESASAPSEDPN S223
SQSTM1 iso2 (rat) gap -
SQSTM1 iso3 (rat) gap -
S233-p
sGPSEDPsVNFLKNV
0 7
SQSTM1 (human) sGPSEDPsVNFLKNV S233-p
SQSTM1 iso2 (human) SGPSEDPSVNFLKNV S149
SQSTM1 (mouse) sAPPEDPNVNFLKNV N233
SQSTM1 iso2 (mouse) SAPPEDPNVNFLKNV N233
SQSTM1 (rat) SAPSEDPNVNFLKNV N230
SQSTM1 iso2 (rat) gap -
SQSTM1 iso3 (rat) gap -
S249-p
ESVAAALsPLGIEVD
Upstream
0 6
Treatment
  • ischemia
  • nocodazole
  • selumetinib
  • vemurafenib
view more >
SQSTM1 (human) ESVAAALsPLGIEVD S249-p
SQSTM1 iso2 (human) ESVAAALSPLGIEVD S165
SQSTM1 (mouse) ESVAAALsPLGIEVD S249-p
SQSTM1 iso2 (mouse) ESVAAALSPLGIEVD S249
SQSTM1 (rat) ESVAAALSPLGIEVD S246
SQSTM1 iso2 (rat) gap -
SQSTM1 iso3 (rat) gap -
S266-p
VEHGGkRsRLtPVsP
Upstream
0 27
Regulatory protein:
  • TBK1 (human)
Treatment
  • nocodazole
SQSTM1 (human) VEHGGkRsRLtPVsP S266-p
SQSTM1 iso2 (human) VEHGGKRSRLTPVSP S182
SQSTM1 (mouse) VEHGGKRsRLtPttP S266-p
SQSTM1 iso2 (mouse) VEHGGKRSRLTPTTP S266
SQSTM1 (rat) VEHGGKRSRLtPTsA S263
SQSTM1 iso2 (rat) VEHGGKRSRLTPTSA S236
SQSTM1 iso3 (rat) gap -
T269-p
GGkRsRLtPVsPEss
Upstream
Downstream
8 209
SQSTM1 (human)
T269-p
SQSTM1 (mouse)
T269-p
SQSTM1 (rat)
T266-p
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
  • phosphorylation
  • protein degradation
  • ubiquitination
Effects on Biological Processes:
  • autophagy, induced
  • autophagy, inhibited
  • carcinogenesis, altered
  • carcinogenesis, induced
  • cell cycle regulation
  • signaling pathway regulation
Kinase, in vitro:
  • CDK1 (human)
  • CDKL5 (human)
  • P38D (human)
view more >
Putative in vivo kinases:
  • CDK1 (human)
  • CDKL5 (human)
  • P38D (human)
  • P38G (human)
view more >
Regulatory protein:
  • MEKK3 (human)
  • SMARCA4 (human)
Treatment
  • amino_acid_starvation
  • amino_acids
  • bafilomycin_A
  • BIRB-0796
  • bortezomib
  • EGF
  • insulin
  • metastatic potential
  • metformin
  • MG132
  • nocodazole
  • PD98059
  • purvalanol
  • SB202190
  • SB203580
  • SB216763
  • siRNA
  • virus infection
  • VX-680
view more >
SQSTM1 (human) GGkRsRLtPVsPEss T269-p
SQSTM1 iso2 (human) GGKRSRLTPVSPESS T185
SQSTM1 (mouse) GGKRsRLtPttPEss T269-p
SQSTM1 iso2 (mouse) GGKRSRLTPTTPESS T269
SQSTM1 (rat) GGKRSRLtPTsAESS T266-p
SQSTM1 iso2 (rat) GGKRSRLTPTSAESS T239
SQSTM1 iso3 (rat) gap -
V271
kRsRLtPVsPEssst
0 9
SQSTM1 (human) kRsRLtPVsPEssst V271
SQSTM1 iso2 (human) KRSRLTPVSPESSST V187
SQSTM1 (mouse) KRsRLtPttPEssst T271-p
SQSTM1 iso2 (mouse) KRSRLTPTTPESSST T271
SQSTM1 (rat) KRSRLtPTsAESSST T268
SQSTM1 iso2 (rat) KRSRLTPTSAESSST T241
SQSTM1 iso3 (rat) gap -
S272-p
RsRLtPVsPEssstE
Upstream
Downstream
8 356
SQSTM1 (human)
S272-p
SQSTM1 (mouse)
T272-p
SQSTM1 (rat)
S269-p
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
  • phosphorylation
  • protein degradation
  • ubiquitination
Effects on Biological Processes:
  • autophagy, induced
  • autophagy, inhibited
  • carcinogenesis, altered
  • carcinogenesis, induced
  • cell cycle regulation
  • signaling pathway regulation
Kinase, in vitro:
  • CDK1 (human)
  • CDKL5 (human)
  • P38D (human)
view more >
Putative in vivo kinases:
  • CDK1 (human)
  • CDKL5 (human)
  • P38D (human)
  • P38G (human)
view more >
Regulatory protein:
  • MEKK3 (human)
  • SMARCA4 (human)
Treatment
  • amino_acid_starvation
  • amino_acids
  • bafilomycin_A
  • BIRB-0796
  • bortezomib
  • EGF
  • insulin
  • metformin
  • MG132
  • MG132_withdrawal
  • nocodazole
  • PD98059
  • purvalanol
  • SB202190
  • SB203580
  • SB216763
  • siRNA
  • virus infection
  • VX-680
view more >
SQSTM1 (human) RsRLtPVsPEssstE S272-p
SQSTM1 iso2 (human) RSRLTPVSPESSSTE S188
SQSTM1 (mouse) RsRLtPttPEssstG T272-p
SQSTM1 iso2 (mouse) RSRLTPTTPESSSTG T272
SQSTM1 (rat) RSRLtPTsAESSSTG S269-p
SQSTM1 iso2 (rat) RSRLTPTSAESSSTG S242
SQSTM1 iso3 (rat) gap -
S275-p
LtPVsPEssstEEks
0 35
SQSTM1 (human) LtPVsPEssstEEks S275-p
SQSTM1 iso2 (human) LTPVSPESSSTEEKS S191
SQSTM1 (mouse) LtPttPEssstGTED S275-p
SQSTM1 iso2 (mouse) LTPTTPESSSTGTED S275
SQSTM1 (rat) LtPTsAESSSTGTED S272
SQSTM1 iso2 (rat) LTPTSAESSSTGTED S245
SQSTM1 iso3 (rat) gap -
S276-p
tPVsPEssstEEksS
0 37
SQSTM1 (human) tPVsPEssstEEksS S276-p
SQSTM1 iso2 (human) TPVSPESSSTEEKSS S192
SQSTM1 (mouse) tPttPEssstGTEDK S276-p
SQSTM1 iso2 (mouse) TPTTPESSSTGTEDK S276
SQSTM1 (rat) tPTsAESSSTGTEDK S273
SQSTM1 iso2 (rat) TPTSAESSSTGTEDK S246
SQSTM1 iso3 (rat) gap -
S277-p
PVsPEssstEEksSs
0 44
SQSTM1 (human) PVsPEssstEEksSs S277-p
SQSTM1 iso2 (human) PVSPESSSTEEKSSS S193
SQSTM1 (mouse) PttPEssstGTEDKS S277-p
SQSTM1 iso2 (mouse) PTTPESSSTGTEDKS S277
SQSTM1 (rat) PTsAESSSTGTEDKS S274
SQSTM1 iso2 (rat) PTSAESSSTGTEDKS S247
SQSTM1 iso3 (rat) gap -
-
gap
0 1
SQSTM1 (human) gap -
SQSTM1 iso2 (human) gap -
SQSTM1 (mouse) ttPEssstGTEDKSN T278-p
SQSTM1 iso2 (mouse) TTPESSSTGTEDKSN T278
SQSTM1 (rat) TsAESSSTGTEDKSG T275
SQSTM1 iso2 (rat) TSAESSSTGTEDKSG T248
SQSTM1 iso3 (rat) gap -
T278-p
VsPEssstEEksSsQ
0 12
SQSTM1 (human) VsPEssstEEksSsQ T278-p
SQSTM1 iso2 (human) VSPESSSTEEKSSSQ T194
SQSTM1 (mouse) PEssstGTEDKSNtQ T280
SQSTM1 iso2 (mouse) PESSSTGTEDKSNTQ T280
SQSTM1 (rat) AESSSTGTEDKSGTQ T277
SQSTM1 iso2 (rat) AESSSTGTEDKSGTQ T250
SQSTM1 iso3 (rat) gap -
S282-p
ssstEEksSsQPssC
Upstream
0 5
Treatment
  • MG132
SQSTM1 (human) ssstEEksSsQPssC S282-p
SQSTM1 iso2 (human) SSSTEEKSSSQPSSC S198
SQSTM1 (mouse) stGTEDKSNtQPSSC S284
SQSTM1 iso2 (mouse) STGTEDKSNTQPSSC S284
SQSTM1 (rat) STGTEDKSGTQPSSC S281
SQSTM1 iso2 (rat) STGTEDKSGTQPSSC S254
SQSTM1 iso3 (rat) gap -
S284-p
stEEksSsQPssCCs
0 7
SQSTM1 (human) stEEksSsQPssCCs S284-p
SQSTM1 iso2 (human) STEEKSSSQPSSCCS S200
SQSTM1 (mouse) GTEDKSNtQPSSCSS T286-p
SQSTM1 iso2 (mouse) GTEDKSNTQPSSCSS T286
SQSTM1 (rat) GTEDKSGTQPSSCSS T283
SQSTM1 iso2 (rat) GTEDKSGTQPSSCSS T256
SQSTM1 iso3 (rat) gap -
S287-p
EksSsQPssCCsDPs
0 2
SQSTM1 (human) EksSsQPssCCsDPs S287-p
SQSTM1 iso2 (human) EKSSSQPSSCCSDPS S203
SQSTM1 (mouse) DKSNtQPSSCSSEVs S289
SQSTM1 iso2 (mouse) DKSNTQPSSCSSEVS S289
SQSTM1 (rat) DKSGTQPSSCSSEVs S286
SQSTM1 iso2 (rat) DKSGTQPSSCSSEVS S259
SQSTM1 iso3 (rat) gap -
S288-p
ksSsQPssCCsDPsk
0 4
SQSTM1 (human) ksSsQPssCCsDPsk S288-p
SQSTM1 iso2 (human) KSSSQPSSCCSDPSK S204
SQSTM1 (mouse) KSNtQPSSCSSEVsk S290
SQSTM1 iso2 (mouse) KSNTQPSSCSSEVSK S290
SQSTM1 (rat) KSGTQPSSCSSEVsK S287
SQSTM1 iso2 (rat) KSGTQPSSCSSEVSK S260
SQSTM1 iso3 (rat) gap -
S291-p
sQPssCCsDPskPGG
0 6
SQSTM1 (human) sQPssCCsDPskPGG S291-p
SQSTM1 iso2 (human) SQPSSCCSDPSKPGG S207
SQSTM1 (mouse) tQPSSCSSEVskPDG S293
SQSTM1 iso2 (mouse) TQPSSCSSEVSKPDG S293
SQSTM1 (rat) TQPSSCSSEVsKPDG S290
SQSTM1 iso2 (rat) TQPSSCSSEVSKPDG S263
SQSTM1 iso3 (rat) gap -
S294-p
ssCCsDPskPGGNVE
Upstream
1 2
Kinase, in vitro:
  • AMPKA1 (human)
SQSTM1 (human) ssCCsDPskPGGNVE S294-p
SQSTM1 iso2 (human) SSCCSDPSKPGGNVE S210
SQSTM1 (mouse) SSCSSEVskPDGAGE S296-p
SQSTM1 iso2 (mouse) SSCSSEVSKPDGAGE S296
SQSTM1 (rat) SSCSSEVsKPDGAGE S293-p
SQSTM1 iso2 (rat) SSCSSEVSKPDGAGE S266
SQSTM1 iso3 (rat) gap -
K295-ac
sCCsDPskPGGNVEG
Upstream
Downstream
1 1
Effects on Modified Protein
  • protein degradation
Effects on Biological Processes:
  • carcinogenesis, inhibited
Treatment
  • nicotinamide
  • trichostatin_A
SQSTM1 (human) sCCsDPskPGGNVEG K295-ac
SQSTM1 iso2 (human) SCCSDPSKPGGNVEG K211
SQSTM1 (mouse) SCSSEVsKPDGAGEG K297
SQSTM1 iso2 (mouse) SCSSEVSKPDGAGEG K297
SQSTM1 (rat) SCSSEVsKPDGAGEG K294
SQSTM1 iso2 (rat) SCSSEVSKPDGAGEG K267
SQSTM1 iso3 (rat) gap -
K295-ub
sCCsDPskPGGNVEG
0 26
SQSTM1 (human) sCCsDPskPGGNVEG K295-ub
SQSTM1 iso2 (human) SCCSDPSKPGGNVEG K211
SQSTM1 (mouse) SCSSEVskPDGAGEG K297-ub
SQSTM1 iso2 (mouse) SCSSEVSKPDGAGEG K297
SQSTM1 (rat) SCSSEVsKPDGAGEG K294
SQSTM1 iso2 (rat) SCSSEVSKPDGAGEG K267
SQSTM1 iso3 (rat) gap -
S306-p
NVEGATQsLAEQMRk
0 6
SQSTM1 (human) NVEGATQsLAEQMRk S306-p
SQSTM1 iso2 (human) NVEGATQSLAEQMRK S222
SQSTM1 (mouse) AGEGPAQsLTEQMkk S308-p
SQSTM1 iso2 (mouse) AGEGPAQSLTEQMKK S308
SQSTM1 (rat) AGEGPAQsLTEQMKK S305-p
SQSTM1 iso2 (rat) AGEGPAQSLTEQMKK S278
SQSTM1 iso3 (rat) gap -
R312
QsLAEQMRkIALEsE
0 2
SQSTM1 (human) QsLAEQMRkIALEsE R312
SQSTM1 iso2 (human) QSLAEQMRKIALESE R228
SQSTM1 (mouse) QsLTEQMkkIALEsV K314-ub
SQSTM1 iso2 (mouse) QSLTEQMKKIALESV K314
SQSTM1 (rat) QsLTEQMKKIALESV K311
SQSTM1 iso2 (rat) QSLTEQMKKIALESV K284
SQSTM1 iso3 (rat) gap -
S318-p
MRkIALEsEGRPEEQ
0 3
SQSTM1 (human) MRkIALEsEGRPEEQ S318-p
SQSTM1 iso2 (human) MRKIALESEGRPEEQ S234
SQSTM1 (mouse) MkkIALEsVGQPEEQ S320-p
SQSTM1 iso2 (mouse) MKKIALESVGQPEEQ S320
SQSTM1 (rat) MKKIALESVGQPEEL S317
SQSTM1 iso2 (rat) MKKIALESVGQPEEL S290
SQSTM1 iso3 (rat) gap -
S328-p
RPEEQMEsDNCsGGD
0 23
SQSTM1 (human) RPEEQMEsDNCsGGD S328-p
SQSTM1 iso2 (human) RPEEQMESDNCSGGD S244
SQSTM1 (mouse) QPEEQMEsGNCsGGD S330-p
SQSTM1 iso2 (mouse) QPEEQMESGNCSGGD S330
SQSTM1 (rat) QPEELMESDNCSGGD S327
SQSTM1 iso2 (rat) QPEELMESDNCSGGD S300
SQSTM1 iso3 (rat) gap -
S332-p
QMEsDNCsGGDDDWt
Upstream
0 36
Regulatory protein:
  • TBK1 (human)
Treatment
  • EGF
  • MG132
SQSTM1 (human) QMEsDNCsGGDDDWt S332-p
SQSTM1 iso2 (human) QMESDNCSGGDDDWT S248
SQSTM1 (mouse) QMEsGNCsGGDDDWt S334-p
SQSTM1 iso2 (mouse) QMESGNCSGGDDDWT S334
SQSTM1 (rat) LMESDNCSGGDDDWT S331
SQSTM1 iso2 (rat) LMESDNCSGGDDDWT S304
SQSTM1 iso3 (rat) gap -
T339-p
sGGDDDWtHLsskEV
0 4
SQSTM1 (human) sGGDDDWtHLsskEV T339-p
SQSTM1 iso2 (human) SGGDDDWTHLSSKEV T255
SQSTM1 (mouse) sGGDDDWtHLSsKEV T341-p
SQSTM1 iso2 (mouse) SGGDDDWTHLSSKEV T341
SQSTM1 (rat) SGGDDDWTHLSSKEV T338
SQSTM1 iso2 (rat) SGGDDDWTHLSSKEV T311
SQSTM1 iso3 (rat) gap -
S342-p
DDDWtHLsskEVDPs
0 5
SQSTM1 (human) DDDWtHLsskEVDPs S342-p
SQSTM1 iso2 (human) DDDWTHLSSKEVDPS S258
SQSTM1 (mouse) DDDWtHLSsKEVDPs S344
SQSTM1 iso2 (mouse) DDDWTHLSSKEVDPS S344
SQSTM1 (rat) DDDWTHLSSKEVDPs S341
SQSTM1 iso2 (rat) DDDWTHLSSKEVDPS S314
SQSTM1 iso3 (rat) gap -
S343-p
DDWtHLsskEVDPst
0 4
SQSTM1 (human) DDWtHLsskEVDPst S343-p
SQSTM1 iso2 (human) DDWTHLSSKEVDPST S259
SQSTM1 (mouse) DDWtHLSsKEVDPsT S345-p
SQSTM1 iso2 (mouse) DDWTHLSSKEVDPST S345
SQSTM1 (rat) DDWTHLSSKEVDPsT S342
SQSTM1 iso2 (rat) DDWTHLSSKEVDPST S315
SQSTM1 iso3 (rat) gap -
K344-ac
DWtHLsskEVDPstG
0 1
SQSTM1 (human) DWtHLsskEVDPstG K344-ac
SQSTM1 iso2 (human) DWTHLSSKEVDPSTG K260
SQSTM1 (mouse) DWtHLSsKEVDPsTG K346
SQSTM1 iso2 (mouse) DWTHLSSKEVDPSTE K346
SQSTM1 (rat) DWTHLSSKEVDPsTG K343
SQSTM1 iso2 (rat) DWTHLSSKEVDPSTG K316
SQSTM1 iso3 (rat) gap -
K344-ub
DWtHLsskEVDPstG
0 1
SQSTM1 (human) DWtHLsskEVDPstG K344-ub
SQSTM1 iso2 (human) DWTHLSSKEVDPSTG K260
SQSTM1 (mouse) DWtHLSsKEVDPsTG K346
SQSTM1 iso2 (mouse) DWTHLSSKEVDPSTE K346
SQSTM1 (rat) DWTHLSSKEVDPsTG K343
SQSTM1 iso2 (rat) DWTHLSSKEVDPSTG K316
SQSTM1 iso3 (rat) gap -
S349-p
sskEVDPstGELQsL
Upstream
Downstream
50 1
SQSTM1 (human)
S349-p
SQSTM1 iso2 (human)
S265-p
SQSTM1 (mouse)
S351-p
SQSTM1 (rat)
S348-p
Effects on Modified Protein
  • activity, induced
  • intracellular localization
  • molecular association, regulation
  • protein conformation
  • protein stabilization
Effects on Biological Processes:
  • apoptosis, inhibited
  • autophagy, induced
  • autophagy, inhibited
  • cell growth, induced
  • signaling pathway regulation
  • transcription, induced
  • transcription, inhibited
Kinase, in vitro:
  • CK1A (human)
  • PKCD (human)
  • ULK1 (human)
view more >
Putative in vivo kinases:
  • CK1A (human)
  • PKACA (human)
  • PKCD (human)
  • ULK1 (human)
view more >
Regulatory protein:
  • ATG2B (human)
  • CASP8 (human)
  • CENPU (human)
  • GSKIP (human)
  • NGLY1 (human)
  • PIK3C3 (human)
  • SLC15A3 (human)
  • TAK1 (human)
  • TBK1 (human)
  • TENT5C (human)
  • TFEB (human)
  • TRIM44 (human)
  • USP10 (human)
  • USP8 (human)
view more >
Treatment
  • As2O3
  • autophinib
  • BafA1
  • bafilomycin_A
  • bortezomib
  • CHIR99021
  • CKI-7
  • cycloheximide
  • cysteine hydrochloride
  • DEM
  • dopamine
  • epoxomicin
  • exercise
  • fingolimod
  • Fugene
  • GDS-23
  • H-89
  • H2O2
  • hypoxia
  • ischemia
  • KN-62
  • KRIBB11
  • licochalcone_A
  • Lipofectamine
  • MG132
  • MHY1485
  • monoammonium glycyrrhizinate
  • MRT68921
  • PP242
  • rotenone
  • serum
  • serum_starvation
  • siRNA
  • TTM
  • ULK-101
  • wortmannin
view more >
SQSTM1 (human) sskEVDPstGELQsL S349-p
SQSTM1 iso2 (human) SSKEVDPSTGELQSL S265
SQSTM1 (mouse) SsKEVDPsTGELQsL S351-p
SQSTM1 iso2 (mouse) SSKEVDPSTEADPRL S351
SQSTM1 (rat) SSKEVDPsTGELQsL S348-p
SQSTM1 iso2 (rat) SSKEVDPSTGELQSL S321
SQSTM1 iso3 (rat) gap -
T350-p
skEVDPstGELQsLQ
Downstream
1 1
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
Effects on Biological Processes:
  • transcription, induced
SQSTM1 (human) skEVDPstGELQsLQ T350-p
SQSTM1 iso2 (human) SKEVDPSTGELQSLQ T266
SQSTM1 (mouse) sKEVDPsTGELQsLQ T352
SQSTM1 iso2 (mouse) SKEVDPSTEADPRLI T352
SQSTM1 (rat) SKEVDPsTGELQsLQ T349
SQSTM1 iso2 (rat) SKEVDPSTGELQSLQ T322
SQSTM1 iso3 (rat) gap -
S355-p
PstGELQsLQMPEsE
0 16
SQSTM1 (human) PstGELQsLQMPEsE S355-p
SQSTM1 iso2 (human) PSTGELQSLQMPESE S271
SQSTM1 (mouse) PsTGELQsLQMPEsE S357-p
SQSTM1 iso2 (mouse) gap -
SQSTM1 (rat) PsTGELQsLQMPEsE S354-p
SQSTM1 iso2 (rat) PSTGELQSLQMPESE S327
SQSTM1 iso3 (rat) gap -
S361-p
QsLQMPEsEGPssLD
Upstream
0 14
Treatment
  • metformin
SQSTM1 (human) QsLQMPEsEGPssLD S361-p
SQSTM1 iso2 (human) QSLQMPESEGPSSLD S277
SQSTM1 (mouse) QsLQMPEsEGPssLD S363-p
SQSTM1 iso2 (mouse) gap -
SQSTM1 (rat) QsLQMPEsEGPSsLD S360-p
SQSTM1 iso2 (rat) QSLQMPESEGPSSLD S333
SQSTM1 iso3 (rat) gap -
S365-p
MPEsEGPssLDPsQE
0 10
SQSTM1 (human) MPEsEGPssLDPsQE S365-p
SQSTM1 iso2 (human) MPESEGPSSLDPSQE S281
SQSTM1 (mouse) MPEsEGPssLDPsQE S367-p
SQSTM1 iso2 (mouse) gap -
SQSTM1 (rat) MPEsEGPSsLDPSQE S364
SQSTM1 iso2 (rat) MPESEGPSSLDPSQE S337
SQSTM1 iso3 (rat) gap -
S366-p
PEsEGPssLDPsQEG
Upstream
Downstream
1 29
SQSTM1 (human)
S366-p
SQSTM1 iso2 (human)
S282-p
SQSTM1 (mouse)
S368-p
SQSTM1 (rat)
S365-p
SQSTM1 iso2 (rat)
S338-p
Effects on Modified Protein
  • protein stabilization
Effects on Biological Processes:
  • carcinogenesis, induced
Kinase, in vitro:
  • TBK1 (human)
Putative in vivo kinases:
  • TBK1 (human)
Treatment
  • EGF
  • MG132
  • siRNA
view more >
SQSTM1 (human) PEsEGPssLDPsQEG S366-p
SQSTM1 iso2 (human) PESEGPSSLDPSQEG S282
SQSTM1 (mouse) PEsEGPssLDPsQEG S368-p
SQSTM1 iso2 (mouse) gap -
SQSTM1 (rat) PEsEGPSsLDPSQEG S365-p
SQSTM1 iso2 (rat) PESEGPSSLDPSQEG S338
SQSTM1 iso3 (rat) gap -
T375-p
DPsQEGPtGLkEAAL
0 3
SQSTM1 (human) DPsQEGPtGLkEAAL T375-p
SQSTM1 iso2 (human) DPSQEGPTGLKEAAL T291
SQSTM1 (mouse) DPsQEGPTGLKEAAL T377
SQSTM1 iso2 (mouse) gap -
SQSTM1 (rat) DPSQEGPTGLKEAAL T374
SQSTM1 iso2 (rat) DPSQEGPTGLKEAAL T347
SQSTM1 iso3 (rat) gap -
K378-ub
QEGPtGLkEAALyPH
0 1
SQSTM1 (human) QEGPtGLkEAALyPH K378-ub
SQSTM1 iso2 (human) QEGPTGLKEAALYPH K294
SQSTM1 (mouse) QEGPTGLKEAALYPH K380
SQSTM1 iso2 (mouse) gap -
SQSTM1 (rat) QEGPTGLKEAALYPH K377
SQSTM1 iso2 (rat) QEGPTGLKEAALYPH K350
SQSTM1 iso3 (rat) gap -
Y383-p
GLkEAALyPHLPPEA
0 3
SQSTM1 (human) GLkEAALyPHLPPEA Y383-p
SQSTM1 iso2 (human) GLKEAALYPHLPPEA Y299
SQSTM1 (mouse) GLKEAALYPHLPPEA Y385
SQSTM1 iso2 (mouse) gap -
SQSTM1 (rat) GLKEAALYPHLPPEA Y382
SQSTM1 iso2 (rat) GLKEAALYPHLPPEA Y355
SQSTM1 iso3 (rat) gap -
S403-p
ESLSQMLsMGFsDEG
Upstream
Downstream
29 6
SQSTM1 (human)
S403-p
SQSTM1 (mouse)
S405-p
SQSTM1 (rat)
S402-p
Effects on Modified Protein
  • activity, induced
  • intracellular localization
  • molecular association, regulation
  • phosphorylation
  • protein degradation
  • ubiquitination
Effects on Biological Processes:
  • autophagy, induced
  • autophagy, inhibited
  • cell differentiation, induced
  • cell growth, induced
  • signaling pathway regulation
  • transcription, induced
Kinase, in vitro:
  • CK2A1 (human)
  • TBK1 (human)
  • ULK1 (human)
view more >
Putative in vivo kinases:
  • CK2A1 (human)
  • TBK1 (human)
Regulatory protein:
  • ATG13 (human)
  • ATG5 (human)
  • CENPU (human)
  • NRF1 (human)
  • RB1CC1 (human)
  • TAX1BP1 (human)
  • TENT5C (human)
view more >
Treatment
  • amlexanox
  • bafilomycin_A
  • BIRB-0796
  • bortezomib
  • BX795
  • CK2_inhibitor
  • cycloheximide
  • DMAT
  • epoxomicin
  • KRIBB11
  • LPS
  • MG132
  • MRT67307
  • MRT68921
  • okadaic_acid
  • poly(I-C)
  • SBI-0206965
  • silmitasertib
  • siRNA
  • starvation
  • ULK-101
  • wortmannin
view more >
SQSTM1 (human) ESLSQMLsMGFsDEG S403-p
SQSTM1 iso2 (human) ESLSQMLSMGFSDEG S319
SQSTM1 (mouse) ESLSQMLsMGFsDEG S405-p
SQSTM1 iso2 (mouse) ESLSQMLSMGFSDEG S367
SQSTM1 (rat) ESLSQMLsMGFSDEG S402-p
SQSTM1 iso2 (rat) ESLSQMLSMGFSDEG S375
SQSTM1 iso3 (rat) gap -
S407-p
QMLsMGFsDEGGWLT
Downstream
3 2
Effects on Modified Protein
  • molecular association, regulation
Effects on Biological Processes:
  • autophagy, induced
SQSTM1 (human) QMLsMGFsDEGGWLT S407-p
SQSTM1 iso2 (human) QMLSMGFSDEGGWLT S323
SQSTM1 (mouse) QMLsMGFsDEGGWLT S409-p
SQSTM1 iso2 (mouse) QMLSMGFSDEGGWLT S371
SQSTM1 (rat) QMLsMGFSDEGGWLT S406
SQSTM1 iso2 (rat) QMLSMGFSDEGGWLT S379
SQSTM1 iso3 (rat) gap -
K420-ub
LTRLLQTkNYDIGAA
Downstream
5 32
Effects on Modified Protein
  • protein degradation
  • ubiquitination
Effects on Biological Processes:
  • autophagy, induced
  • autophagy, inhibited
  • cell growth, induced
SQSTM1 (human) LTRLLQTkNYDIGAA K420-ub
SQSTM1 iso2 (human) LTRLLQTKNYDIGAA K336
SQSTM1 (mouse) LTRLLQTkNYDIGAA K422-ub
SQSTM1 iso2 (mouse) LTRLLQTKNYDIGAA K384
SQSTM1 (rat) LTRLLQTKNYDIGAA K419
SQSTM1 iso2 (rat) LTRLLQTKNYDIGAA K392
SQSTM1 iso3 (rat) gap -
T430-p
DIGAALDtIQyskHP
0 1
SQSTM1 (human) DIGAALDtIQyskHP T430-p
SQSTM1 iso2 (human) DIGAALDTIQYSKHP T346
SQSTM1 (mouse) DIGAALDTIQYSkHP T432
SQSTM1 iso2 (mouse) DIGAALDTIQYSKHP T394
SQSTM1 (rat) DIGAALDTIQYSKHP T429
SQSTM1 iso2 (rat) DIGAALDTIQYSKHP T402
SQSTM1 iso3 (rat) gap -
Y433-p
AALDtIQyskHPPPL
Upstream
Downstream
1 3
Effects on Modified Protein
  • activity, inhibited
  • molecular association, regulation
  • protein stabilization
Effects on Biological Processes:
  • autophagy, inhibited
  • carcinogenesis, induced
Putative in vivo kinases:
  • EGFR (human)
Treatment
  • EGF
  • siRNA
SQSTM1 (human) AALDtIQyskHPPPL Y433-p
SQSTM1 iso2 (human) AALDTIQYSKHPPPL Y349
SQSTM1 (mouse) AALDTIQYSkHPPPL Y435
SQSTM1 iso2 (mouse) AALDTIQYSKHPPPL Y397
SQSTM1 (rat) AALDTIQYSKHPPPL Y432
SQSTM1 iso2 (rat) AALDTIQYSKHPPPL Y405
SQSTM1 iso3 (rat) gap -
S434-p
ALDtIQyskHPPPL_
0 2
SQSTM1 (human) ALDtIQyskHPPPL_ S434-p
SQSTM1 iso2 (human) ALDTIQYSKHPPPL_ S350
SQSTM1 (mouse) ALDTIQYSkHPPPL_ S436
SQSTM1 iso2 (mouse) ALDTIQYSKHPPPL_ S398
SQSTM1 (rat) ALDTIQYSKHPPPL_ S433
SQSTM1 iso2 (rat) ALDTIQYSKHPPPL_ S406
SQSTM1 iso3 (rat) gap -
K435-ac
LDtIQyskHPPPL__
Downstream
1 1
Effects on Modified Protein
  • molecular association, regulation
SQSTM1 (human) LDtIQyskHPPPL__ K435-ac
SQSTM1 iso2 (human) LDTIQYSKHPPPL__ K351
SQSTM1 (mouse) LDTIQYSKHPPPL__ K437
SQSTM1 iso2 (mouse) LDTIQYSKHPPPL__ K399
SQSTM1 (rat) LDTIQYSKHPPPL__ K434
SQSTM1 iso2 (rat) LDTIQYSKHPPPL__ K407
SQSTM1 iso3 (rat) gap -
K435-ub
LDtIQyskHPPPL__
Downstream
1 105
Effects on Modified Protein
  • intracellular localization
Effects on Biological Processes:
  • signaling pathway regulation
SQSTM1 (human) LDtIQyskHPPPL__ K435-ub
SQSTM1 iso2 (human) LDTIQYSKHPPPL__ K351
SQSTM1 (mouse) LDTIQYSkHPPPL__ K437-ub
SQSTM1 iso2 (mouse) LDTIQYSKHPPPL__ K399
SQSTM1 (rat) LDTIQYSKHPPPL__ K434
SQSTM1 iso2 (rat) LDTIQYSKHPPPL__ K407
SQSTM1 iso3 (rat) gap -