Other Species / Isoforms
  HDAC8 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
S39-p
AKIPKRAsMVHsLIE
Upstream
Downstream
3 2
Effects on Modified Protein
  • acetylation
  • enzymatic activity, inhibited
  • protein conformation
Kinase, in vitro:
  • PKACA (human)
Putative in vivo kinases:
  • PKACA (human)
Treatment
  • colforsin
  • H-89
HDAC8 (human) AKIPKRAsMVHsLIE S39-p
HDAC8 iso5 (human) AKIPKRASMVHSLIE S39
HDAC8 iso6 (human) AKIPKRASMVHSLIE S39
HDAC8 (mouse) VKVPKRASMVHSLIE S39
HDAC8 (rat) VKVPKRASMVHSLIE S39
S43-p
KRAsMVHsLIEAyAL
0 2
HDAC8 (human) KRAsMVHsLIEAyAL S43-p
HDAC8 iso5 (human) KRASMVHSLIEAYAL S43
HDAC8 iso6 (human) KRASMVHSLIEAYAL S43
HDAC8 (mouse) KRASMVHSLIEAYAL S43
HDAC8 (rat) KRASMVHSLIEAYAL S43
Y48-p
VHsLIEAyALHKQMR
0 2
HDAC8 (human) VHsLIEAyALHKQMR Y48-p
HDAC8 iso5 (human) VHSLIEAYALHKQMR Y48
HDAC8 iso6 (human) VHSLIEAYALHKQMR Y48
HDAC8 (mouse) VHSLIEAYALHKQMR Y48
HDAC8 (rat) VHSLIEAYALHKQMR Y48
S63-p
IVKPKVAsMEEMATF
0 1
HDAC8 (human) IVKPKVAsMEEMATF S63-p
HDAC8 iso5 (human) IVKPKVASMEEMATF S63
HDAC8 iso6 (human) gap -
HDAC8 (mouse) IVKPKVASMEEMATF S63
HDAC8 (rat) IVKPKVASMEEMATF S63
K221-ub
VSDVGLGkGRYYSVN
0 5
HDAC8 (human) VSDVGLGkGRYYSVN K221-ub
HDAC8 iso5 (human) VSDVGLGKGRYYSVN K221
HDAC8 iso6 (human) VSDVGLGKGRYYSVN K104
HDAC8 (mouse) MSDVGLGKGRYYSVN K221
HDAC8 (rat) MSDVGLGKGRyySVN K221
Y224
VGLGkGRYYSVNVPI
0 1
HDAC8 (human) VGLGkGRYYSVNVPI Y224
HDAC8 iso5 (human) VGLGKGRYYSVNVPI Y224
HDAC8 iso6 (human) VGLGKGRYYSVNVPI Y107
HDAC8 (mouse) VGLGKGRYYSVNVPI Y224
HDAC8 (rat) VGLGKGRyySVNVPI Y224-p
Y225
GLGkGRYYSVNVPIQ
0 1
HDAC8 (human) GLGkGRYYSVNVPIQ Y225
HDAC8 iso5 (human) GLGKGRYYSVNVPIQ Y225
HDAC8 iso6 (human) GLGKGRYYSVNVPIQ Y108
HDAC8 (mouse) GLGKGRYYSVNVPIQ Y225
HDAC8 (rat) GLGKGRyySVNVPIQ Y225-p
Y252-p
ESVLKEVyQAFNPKA
0 1
HDAC8 (human) ESVLKEVyQAFNPKA Y252-p
HDAC8 iso5 (human) gap -
HDAC8 iso6 (human) gap -
HDAC8 (mouse) ESVLKEVYQAFNPKA Y252
HDAC8 (rat) ESVLKEVYQAFNPKA Y252
K370-ub
QQILNYIkGNLKHVV
Upstream
0 1
Treatment
  • MG132
HDAC8 (human) QQILNYIkGNLKHVV K370-ub
HDAC8 iso5 (human) gap -
HDAC8 iso6 (human) gap -
HDAC8 (mouse) QQILNYIKGNLKHVV K370
HDAC8 (rat) QQILNYIKGNLKHVV K370