Other Species / Isoforms
  LIFR (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

  HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
N169
SVFPHRSNVIWEIKV
0 1
LIFR (human) SVFPHRSNVIWEIKV N169
LIFR (mouse) SALPHPSnATWEIKV N164-ng
LIFR (rat) SALPYPSNATWEVKV N165
K179-ub
WEIKVLRkESMELVk
0 1
LIFR (human) WEIKVLRkESMELVk K179-ub
LIFR (mouse) WEIKVLQNPRtEPVA N174
LIFR (rat) WEVKVLQNPRTEPVA N175
M182
KVLRkESMELVkLVT
0 1
LIFR (human) KVLRkESMELVkLVT M182
LIFR (mouse) KVLQNPRtEPVALVL T177-p
LIFR (rat) KVLQNPRTEPVALVS T178
K186-ub
kESMELVkLVTHNTT
0 1
LIFR (human) kESMELVkLVTHNTT K186-ub
LIFR (mouse) NPRtEPVALVLLNtM A181
LIFR (rat) NPRTEPVALVSLNTV A182
T192
VkLVTHNTTLNGKDT
0 1
LIFR (human) VkLVTHNTTLNGKDT T192
LIFR (mouse) VALVLLNtMLSGKDT T187-p
LIFR (rat) VALVSLNTVLSGKDK T188
S204
KDTLHHWSWASDMPL
0 1
LIFR (human) KDTLHHWSWASDMPL S204
LIFR (mouse) KDTVQHWnWTSDLPL N199-ng
LIFR (rat) KDKGHHWNWTSELPL N200
N243
SDWSPVKNISWIPDS
0 1
LIFR (human) SDWSPVKNISWIPDS N243
LIFR (mouse) SDWSPLKnISWIRNT N238-ng
LIFR (rat) SEWSPLKNISWTRNT N239
K253-ub
WIPDSQTkVFPQDKV
0 1
LIFR (human) WIPDSQTkVFPQDKV K253-ub
LIFR (mouse) WIRNTETNVFPQDKV N248
LIFR (rat) WTRNTETNVFPQDKV N249
D266
KVILVGSDITFCCVS
0 1
LIFR (human) KVILVGSDITFCCVS D266
LIFR (mouse) KVVLAGSnMTICCMS N261-ng
LIFR (rat) KVVLAGSNMTICCIS N262
Y369-p
VGPRATSyTLVESFS
0 1
LIFR (human) VGPRATSyTLVESFS Y369-p
LIFR (mouse) VGPRNTEYTLFESIS Y364
LIFR (rat) VGPRNTEYTLFESIS Y365
Y379-p
VESFSGKyVRLKRAE
0 2
LIFR (human) VESFSGKyVRLKRAE Y379-p
LIFR (mouse) FESISGKSAVFHRIE S374
LIFR (rat) FESISGKSAVFHRFE S375
N390
KRAEAPTNESYQLLF
0 1
LIFR (human) KRAEAPTNESYQLLF N390
LIFR (mouse) HRIEGLTnETYRLGV N385-ng
LIFR (rat) HRFEELANETYWLTL N386
N407
LPNQEIYNFTLNAHN
0 1
LIFR (human) LPNQEIYNFTLNAHN N407
LIFR (mouse) HPGQEIHnFTLTGRN N402-ng
LIFR (rat) APDQEIHNFTLTARN N403
N426
SQSTILVNITEKVYP
0 1
LIFR (human) SQSTILVNITEKVYP N426
LIFR (mouse) AQSAVVInVTERVAP N421-ng
LIFR (rat) TESAIVINATERVAL N422
N445
SFKVKDINSTAVKLS
0 1
LIFR (human) SFKVKDINSTAVKLS N445
LIFR (mouse) SLKVKDInSTVVTFS N440-ng
LIFR (rat) SLKVKDVNSTVVTLS N441
N458
LSWHLPGNFAKINFL
0 1
LIFR (human) LSWHLPGNFAKINFL N458
LIFR (mouse) FSWYLPGnFTKINLL N453-ng
LIFR (rat) LSWYLPGNFTKINLV N454
N481
NSVQEQRNVTIKGVE
0 1
LIFR (human) NSVQEQRNVTIKGVE N481
LIFR (mouse) NSKKEVRnATIRGAE N476-ng
LIFR (rat) NSKKEVRNVTMRGAE N477
S490-p
TIKGVENssyLVALD
0 1
LIFR (human) TIKGVENssyLVALD S490-p
LIFR (mouse) TIRGAEDSTYHVAVD S485
LIFR (rat) TMRGAEDSTYHVAVD S486
S491-p
IKGVENssyLVALDK
0 1
LIFR (human) IKGVENssyLVALDK S491-p
LIFR (mouse) IRGAEDSTYHVAVDK T486
LIFR (rat) MRGAEDSTYHVAVDK T487
Y492-p
KGVENssyLVALDKL
0 1
LIFR (human) KGVENssyLVALDKL Y492-p
LIFR (mouse) RGAEDSTYHVAVDKL Y487
LIFR (rat) RGAEDSTYHVAVDKL Y488
R510
TLYTFRIRCSTETFW
0 1
LIFR (human) TLYTFRIRCSTETFW R510
LIFR (mouse) TAYTFRVrCSSKTFW R505-m2
LIFR (rat) TIYTFRVRCSSETFW R506
K526-ub
WSKWSNKkQHLTTEA
0 1
LIFR (human) WSKWSNKkQHLTTEA K526-ub
LIFR (mouse) WSRWSDEKRHLTTEA K521
LIFR (rat) WSKWSNEKRYLTTEA K522
N572
NGKILSYNVSCSSDE
0 1
LIFR (human) NGKILSYNVSCSSDE N572
LIFR (mouse) NGKILSYnVSCSLNE N567-ng
LIFR (rat) NGKILSYNVSCSSSE N568
K610-ac
YIISVVAkNSVGSSP
0 1
LIFR (human) YIISVVAkNSVGSSP K610-ac
LIFR (mouse) YIISVVARNSAGSSP R605
LIFR (rat) YIISVVARNSAGSSP R606
N652
LTWHYDPNMTCDYVI
0 1
LIFR (human) LTWHYDPNMTCDYVI N652
LIFR (mouse) LTWRHDPnMTCDYVI N647-ng
LIFR (rat) LSWQHNPNMTCDYVI N648
N663
DYVIKWCNSsRSEPC
0 1
LIFR (human) DYVIKWCNSsRSEPC N663
LIFR (mouse) DYVIKWCnSSRSEPC N658-ng
LIFR (rat) DYVIKWCNSSWSEPC N659
S665-p
VIKWCNSsRSEPCLM
0 1
LIFR (human) VIKWCNSsRSEPCLM S665-p
LIFR (mouse) VIKWCnSSRSEPCLL S660
LIFR (rat) VIKWCNSSWSEPCLL S661
N680
DWRKVPSNSTETVIE
0 1
LIFR (human) DWRKVPSNSTETVIE N680
LIFR (mouse) DWRKVPSnSTETVIE N675-ng
LIFR (rat) DWIKVPSNSTGTVIE N676
Y759-p
LRGFLRGyLFyFGKG
0 1
LIFR (human) LRGFLRGyLFyFGKG Y759-p
LIFR (mouse) LRGFLRGYLFYFQKG Y754
LIFR (rat) LRGFLRGYLFYFQKG Y755
Y762-p
FLRGyLFyFGKGERD
0 1
LIFR (human) FLRGyLFyFGKGERD Y762-p
LIFR (mouse) FLRGYLFYFQKGERD Y757
LIFR (rat) FLRGYLFYFQKGERD Y758
N787
RSDIKVKNITDISQK
0 1
LIFR (human) RSDIKVKNITDISQK N787
LIFR (mouse) HSDIKLKnITDISQK N782-ng
LIFR (rat) HSDIKLKNITDISQK N783
K804-ub
RIADLQGkTSyHLVL
0 1
LIFR (human) RIADLQGkTSyHLVL K804-ub
LIFR (mouse) RIADLQGKTSYHLVL K799
LIFR (rat) RIADLQGKTSYHLVL K800
Y807-p
DLQGkTSyHLVLRAY
0 2
LIFR (human) DLQGkTSyHLVLRAY Y807-p
LIFR (mouse) DLQGKTSYHLVLRAY Y802
LIFR (rat) DLQGKTSYHLVLRAY Y803
S833-p
YVVTKENsVGLIIAI
0 1
LIFR (human) YVVTKENsVGLIIAI S833-p
LIFR (mouse) FVVTKENSVGLIIAI S828
LIFR (rat) FVVTKENSVGLIIAI S829
K866-ub
YRKREWIkETFYPDI
0 2
LIFR (human) YRKREWIkETFYPDI K866-ub
LIFR (mouse) YRKREWIkETFYPDI K861-ub
LIFR (rat) YRKREWIKETFYPDI K862
K880-ac
IPNPENCkALQFQks
Upstream
Downstream
1 1
Effects on Modified Protein
  • protein conformation
Treatment
  • LIF
LIFR (human) IPNPENCkALQFQks K880-ac
LIFR (mouse) IPNPENCKALQFQks K875
LIFR (rat) IPNPENCKALQFQKS K876
K880-ub
IPNPENCkALQFQks
0 2
LIFR (human) IPNPENCkALQFQks K880-ub
LIFR (mouse) IPNPENCKALQFQks K875
LIFR (rat) IPNPENCKALQFQKS K876
K886-ac
CkALQFQksVCEGSS
Upstream
Downstream
1 1
Effects on Modified Protein
  • protein conformation
Treatment
  • LIF
LIFR (human) CkALQFQksVCEGSS K886-ac
LIFR (mouse) CKALQFQKsVCEGSN K881
LIFR (rat) CKALQFQKSVCEGSN K882
K886-ub
CkALQFQksVCEGSS
0 4
LIFR (human) CkALQFQksVCEGSS K886-ub
LIFR (mouse) CKALQFQksVCEGSN K881-ub
LIFR (rat) CKALQFQKSVCEGSN K882
S887-p
kALQFQksVCEGSSA
Downstream
1 8
Effects on Modified Protein
  • protein conformation
LIFR (human) kALQFQksVCEGSSA S887-p
LIFR (mouse) KALQFQksVCEGSNA S882-p
LIFR (rat) KALQFQKSVCEGSNA S883
K896-ac
CEGSSALkTLEMNPC
1 1
LIFR (human) CEGSSALkTLEMNPC K896-ac
LIFR (mouse) CEGSNALKTLEMNPC K891
LIFR (rat) CEGSNALKTLEMNPC K892
T904-p
TLEMNPCtPNNVEVL
0 1
LIFR (human) TLEMNPCtPNNVEVL T904-p
LIFR (mouse) TLEMNPCTPNNVEVL T899
LIFR (rat) TLEMNPCTPNHVEVL T900
S927-p
IEDTEIIsPVAERPE
Upstream
0 7
Treatment
  • BI_4834
LIFR (human) IEDTEIIsPVAERPE S927-p
LIFR (mouse) IEDTEIIsPVAERPG S922-p
LIFR (rat) IEDTEITSPVSERPG S923
Y974-p
GGTAQVIyIDVQSMY
1 0
LIFR (human) GGTAQVIyIDVQSMY Y974-p
LIFR (mouse) GGASQVVYIDVQSMY Y969
LIFR (rat) GGASQVVYIDVQSMY Y970
S1041-p
VNTWNLVsPDsPRsI
1 2
LIFR (human) VNTWNLVsPDsPRsI S1041-p
LIFR (mouse) VNTWNLVSPDsPRST S1036
LIFR (rat) VNTWNLVSPDSPRST S1037
S1044-p
WNLVsPDsPRsIDSN
Upstream
Downstream
6 5
Effects on Modified Protein
  • activity, induced
  • activity, inhibited
  • intracellular localization
  • protein degradation
Effects on Biological Processes:
  • carcinogenesis, induced
  • cell adhesion, induced
  • cell growth, induced
  • cell motility, induced
  • signaling pathway regulation
  • transcription, inhibited
Kinase, in vitro:
  • ERK1 (human)
  • ERK2 (human)
Putative in vivo kinases:
  • ERK1 (human)
  • ERK1 (rat)
  • ERK2 (human)
  • ERK2 (rat)
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Regulatory protein:
  • ERK1 (human)
  • ERK2 (human)
Treatment
  • Akt_inhibitor_X
  • CHIR99021
  • EGF
  • insulin
  • LIF
  • LY3214996
  • PD0325901
  • PD98059
  • phorbol_ester
  • SC1
  • ulixertinib
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LIFR (human) WNLVsPDsPRsIDSN S1044-p
LIFR (mouse) WNLVSPDsPRSTDSN S1039-p
LIFR (rat) WNLVSPDSPRSTDSN S1040
S1047-p
VsPDsPRsIDSNSEI
0 1
LIFR (human) VsPDsPRsIDSNSEI S1047-p
LIFR (mouse) VSPDsPRSTDSNNEV S1042
LIFR (rat) VSPDSPRSTDSNSEV S1043
S1059-p
SEIVSFGsPCSINSR
1 2
LIFR (human) SEIVSFGsPCSINSR S1059-p
LIFR (mouse) NEVVSFGSPCSINSR S1054
LIFR (rat) SEVVSFGSPCSINSR S1055
S1077-p
IPPKDEDsPKSNGGG
Upstream
1 5
Treatment
  • CHIR99021
  • LIF
  • PD0325901
view more >
LIFR (human) IPPKDEDsPKSNGGG S1077-p
LIFR (mouse) IPPKDEDsPKSNGGG S1072-p
LIFR (rat) IPPKDEDSPKSNGGG S1073