Other Species / Isoforms
  XIAP (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
S5-p
___MTFNsFEGSkTC
0 1
XIAP (human) ___MTFNsFEGSkTC S5-p
XIAP (mouse) ___MTFNSFEGTRTF S5
XIAP (rat) ___MTFNSFEGSRTV S5
K10-ub
FNsFEGSkTCVPADI
0 2
XIAP (human) FNsFEGSkTCVPADI K10-ub
XIAP (mouse) FNSFEGTRTFVLADT R10
XIAP (rat) FNSFEGSRTVVPADT R10
K19-ub
CVPADINkEEEFVEE
0 3
XIAP (human) CVPADINkEEEFVEE K19-ub
XIAP (mouse) FVLADTNkDEEFVEE K19-ub
XIAP (rat) VVPADTNKDEEFVEE K19
K31-ub
VEEFNRLktFANFPS
0 10
XIAP (human) VEEFNRLktFANFPS K31-ub
XIAP (mouse) VEEFNRLkTFANFPS K31-ub
XIAP (rat) VEEFNRLKTFANFPS K31
T32-p
EEFNRLktFANFPSG
0 2
XIAP (human) EEFNRLktFANFPSG T32-p
XIAP (mouse) EEFNRLkTFANFPSS T32
XIAP (rat) EEFNRLKTFANFPSS T32
S40-p
FANFPSGsPVSAstL
Upstream
Downstream
1 1
Effects on Modified Protein
  • molecular association, regulation
Effects on Biological Processes:
  • apoptosis, induced
Kinase, in vitro:
  • CDK1 (human)
Treatment
  • purvalanol
  • RO-3306
  • wortmannin
XIAP (human) FANFPSGsPVSAstL S40-p
XIAP (mouse) FANFPSSSPVSASTL S40
XIAP (rat) FANFPSSSPVSASTL S40
S45-p
SGsPVSAstLARAGF
0 2
XIAP (human) SGsPVSAstLARAGF S45-p
XIAP (mouse) SSSPVSASTLARAGF S45
XIAP (rat) SSSPVSASTLARAGF S45
T46-p
GsPVSAstLARAGFL
0 2
XIAP (human) GsPVSAstLARAGFL T46-p
XIAP (mouse) SSPVSASTLARAGFL T46
XIAP (rat) SSPVSASTLARAGFL T46
S87-p
VGRHRKVsPNCRFIN
Upstream
Downstream
10 0
Effects on Modified Protein
  • activity, induced
  • enzymatic activity, induced
  • molecular association, regulation
  • protein stabilization
Effects on Biological Processes:
  • apoptosis, altered
  • apoptosis, inhibited
  • autophagy, inhibited
  • carcinogenesis, induced
  • cell growth, induced
  • signaling pathway regulation
Kinase, in vitro:
  • Akt1 (human)
  • Akt2 (human)
Putative in vivo kinases:
  • Akt1 (human)
  • Akt2 (human)
  • PKCE (human)
Regulatory protein:
  • CYP1B1 (human)
  • NQO1 (human)
  • SIRT6 (human)
  • TRIP10 (human)
Treatment
  • API-2
  • BNTX
  • clobetasol
  • dicoumarol
  • EBSS
  • estradiol
  • insulin
  • LY294002
  • MK-2206
  • serum_starvation
  • siRNA
  • TRAIL
XIAP (human) VGRHRKVsPNCRFIN S87-p
XIAP (mouse) VGRHRRIsPNCRFIN S87-p
XIAP (rat) VGRHRRISPNCRFIN S87
K116-ub
GIQNGQYkVENyLGs
0 3
XIAP (human) GIQNGQYkVENyLGs K116-ub
XIAP (mouse) GIQNGQYKSENCVGN K116
XIAP (rat) GIQNGQYKSENCVGN K116
Y120-p
GQYkVENyLGsRDHF
0 1
XIAP (human) GQYkVENyLGsRDHF Y120-p
XIAP (mouse) GQYKSENCVGNRNPF C120
XIAP (rat) GQYKSENCVGNRNHF C120
S123-p
kVENyLGsRDHFALD
0 1
XIAP (human) kVENyLGsRDHFALD S123-p
XIAP (mouse) KSENCVGNRNPFAPD N123
XIAP (rat) KSENCVGNRNHFALD N123
R131-m1
RDHFALDrPSETHAD
0 1
XIAP (human) RDHFALDrPSETHAD R131-m1
XIAP (mouse) RNPFAPDRPPETHAD R131
XIAP (rat) RNHFALDRPSETHAD R131
Y139-p
PSETHADyLLRTGQV
1 2
XIAP (human) PSETHADyLLRTGQV Y139-p
XIAP (mouse) PPETHADYLLRTGQV Y139
XIAP (rat) PSETHADyLLRTGQV Y139-p
K168-ub
YSEEARLkSFQNWPD
0 8
XIAP (human) YSEEARLkSFQNWPD K168-ub
XIAP (mouse) CSEEARLksFQNWPD K168-ub
XIAP (rat) CSEEARLKTFQNWPD K168
S169
SEEARLkSFQNWPDY
0 1
XIAP (human) SEEARLkSFQNWPDY S169
XIAP (mouse) SEEARLksFQNWPDY S169-p
XIAP (rat) SEEARLKTFQNWPDY T169
T180-p
WPDYAHLtPRELASA
Upstream
Downstream
1 4
Effects on Modified Protein
  • enzymatic activity, induced
  • ubiquitination
Kinase, in vitro:
  • GSK3B (human)
XIAP (human) WPDYAHLtPRELASA T180-p
XIAP (mouse) WPDYAHLTPRELASA T180
XIAP (rat) WPDYAHLSPRELASA S180
K208-ub
FCCGGKLkNWEPCDR
0 2
XIAP (human) FCCGGKLkNWEPCDR K208-ub
XIAP (mouse) FCCGGKLKNWEPCDR K208
XIAP (rat) FCCGGKLKNWEPCDR K208
S218-p
EPCDRAWsEHRRHFP
0 1
XIAP (human) EPCDRAWsEHRRHFP S218-p
XIAP (mouse) EPCDRAWsEHRRHFP S218-p
XIAP (rat) EPCDRAWSEHRRHFP S218
R248-m1
SDAVSSDrNFPNSTN
0 1
XIAP (human) SDAVSSDrNFPNSTN R248-m1
XIAP (mouse) ESGVSSDRNFPNSTN R247
XIAP (rat) ESGVSSDRNFPNSTN R247
K297-ub
YALGEGDkVkCFHCG
0 2
XIAP (human) YALGEGDkVkCFHCG K297-ub
XIAP (mouse) YALGEGDKVKCFHCG K296
XIAP (rat) YALGEGDKVKCFHCG K296
K299-ub
LGEGDkVkCFHCGGG
0 1
XIAP (human) LGEGDkVkCFHCGGG K299-ub
XIAP (mouse) LGEGDKVKCFHCGGG K298
XIAP (rat) LGEGDKVKCFHCGGG K298
K311-ub
GGGLTDWkPSEDPWE
0 2
XIAP (human) GGGLTDWkPSEDPWE K311-ub
XIAP (mouse) GGGLTDWKPSEDPWE K310
XIAP (rat) GGGLTDWKPSEDPWE K310
K322-ub
DPWEQHAkWYPGCkY
1 1
XIAP (human) DPWEQHAkWYPGCkY K322-ub
XIAP (mouse) DPWEQHAKWYPGCKY K321
XIAP (rat) DPWEQHAKWYPGCKY K321
K328-ub
AkWYPGCkYLLEQkG
1 2
XIAP (human) AkWYPGCkYLLEQkG K328-ub
XIAP (mouse) AKWYPGCKYLLDEKG K327
XIAP (rat) AKWYPGCKYLLDEKG K327
K334-ub
CkYLLEQkGQEYINN
0 2
XIAP (human) CkYLLEQkGQEYINN K334-ub
XIAP (mouse) CKYLLDEKGQEYINN K333
XIAP (rat) CKYLLDEKGQEYINN K333
S347-p
NNIHLTHsLEECLVR
0 1
XIAP (human) NNIHLTHsLEECLVR S347-p
XIAP (mouse) NNIHLTHSLEESLGR S346
XIAP (rat) NNIHLTHSLGESVVR S346
K358-ub
CLVRTTEkTPsLTRR
0 6
XIAP (human) CLVRTTEkTPsLTRR K358-ub
XIAP (mouse) SLGRTAEKTPSLTKK K357
XIAP (rat) SVVRTAEKTPSVTKK K357
S361-p
RTTEkTPsLTRRIDD
0 2
XIAP (human) RTTEkTPsLTRRIDD S361-p
XIAP (mouse) RTAEKTPSLTKKIDD S360
XIAP (rat) RTAEKTPSVTKKIDD S360
K387-ub
IRMGFSFkDIKKIME
0 1
XIAP (human) IRMGFSFkDIKKIME K387-ub
XIAP (mouse) IRMGFSFKDIKKTME K386
XIAP (rat) IRMGFNFKDIKKTME K386
K396-ub
IKKIMEEkIQIsGsN
0 1
XIAP (human) IKKIMEEkIQIsGsN K396-ub
XIAP (mouse) IKKTMEEKIQTSGSS K395
XIAP (rat) IKKTMEEKLQTSGSN K395
S400-p
MEEkIQIsGsNyksL
0 1
XIAP (human) MEEkIQIsGsNyksL S400-p
XIAP (mouse) MEEKIQTSGSSYLSL S399
XIAP (rat) MEEKLQTSGSNYLSL S399
S402-p
EkIQIsGsNyksLEV
0 2
XIAP (human) EkIQIsGsNyksLEV S402-p
XIAP (mouse) EKIQTSGSSYLSLEV S401
XIAP (rat) EKLQTSGSNYLSLEV S401
Y404-p
IQIsGsNyksLEVLV
0 2
XIAP (human) IQIsGsNyksLEVLV Y404-p
XIAP (mouse) IQTSGSSYLSLEVLI Y403
XIAP (rat) LQTSGSNYLSLEVLI Y403
K405-ub
QIsGsNyksLEVLVA
0 4
XIAP (human) QIsGsNyksLEVLVA K405-ub
XIAP (mouse) QTSGSSYLSLEVLIA L404
XIAP (rat) QTSGSNYLSLEVLIA L404
K405-sm
QIsGsNyksLEVLVA
0 2
XIAP (human) QIsGsNyksLEVLVA K405-sm
XIAP (mouse) QTSGSSYLSLEVLIA L404
XIAP (rat) QTSGSNYLSLEVLIA L404
S406-p
IsGsNyksLEVLVAD
0 2
XIAP (human) IsGsNyksLEVLVAD S406-p
XIAP (mouse) TSGSSYLSLEVLIAD S405
XIAP (rat) TSGSNYLSLEVLIAD S405
K419-ub
ADLVNAQkDSMQDES
0 1
XIAP (human) ADLVNAQkDSMQDES K419-ub
XIAP (mouse) ADLVSAQKDNTEDES K418
XIAP (rat) ADLVSAQKDNSQDES K418
T429-p
MQDESSQtsLQkEIs
0 1
XIAP (human) MQDESSQtsLQkEIs T429-p
XIAP (mouse) TEDESSQTSLQKDIS T428
XIAP (rat) SQDESSQTSLQKDIS T428
S430-p
QDESSQtsLQkEIst
Upstream
Downstream
1 1
Effects on Modified Protein
  • protein degradation
  • ubiquitination
Putative in vivo kinases:
  • IKKE (human)
XIAP (human) QDESSQtsLQkEIst S430-p
XIAP (mouse) EDESSQTSLQKDIST S429
XIAP (rat) QDESSQTSLQKDIST S429
K433-ub
SSQtsLQkEIstEEQ
0 2
XIAP (human) SSQtsLQkEIstEEQ K433-ub
XIAP (mouse) SSQTSLQKDISTEEQ K432
XIAP (rat) SSQTSLQKDISTEEQ K432
S436-p
tsLQkEIstEEQLRR
0 1
XIAP (human) tsLQkEIstEEQLRR S436-p
XIAP (mouse) TSLQKDISTEEQLRR S435
XIAP (rat) TSLQKDISTEEQLRR S435
T437-p
sLQkEIstEEQLRRL
0 1
XIAP (human) sLQkEIstEEQLRRL T437-p
XIAP (mouse) SLQKDISTEEQLRRL T436
XIAP (rat) SLQKDISTEEQLRRL T436
K480-ub
QCAEAVDkCPMCytV
0 1
XIAP (human) QCAEAVDkCPMCytV K480-ub
XIAP (mouse) QCAEAVDKCPMCYTV K479
XIAP (rat) QCAEAVDKCPMCCTV K479
Y485-p
VDkCPMCytVItFKQ
0 1
XIAP (human) VDkCPMCytVItFKQ Y485-p
XIAP (mouse) VDKCPMCYTVITFKQ Y484
XIAP (rat) VDKCPMCCTVITFKQ C484
T486-p
DkCPMCytVItFKQK
0 1
XIAP (human) DkCPMCytVItFKQK T486-p
XIAP (mouse) DKCPMCYTVITFKQK T485
XIAP (rat) DKCPMCCTVITFKQK T485
T489-p
PMCytVItFKQKIFM
0 1
XIAP (human) PMCytVItFKQKIFM T489-p
XIAP (mouse) PMCYTVITFKQKIFM T488
XIAP (rat) PMCCTVITFKQKIFM T488