Other Species / Isoforms
  MPL (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
S81-p
PRACPLSsQSMPHFG
0 1
MPL (human) PRACPLSsQSMPHFG S81-p
MPL (mouse) PRACPLYSQSVPTFG S81
MPL (rat) PRPCPLHSQSVPTFG S81
MPL (zebrafish) EKRCDVKQQTFEEKI Q77
N117
WVKNVFLNQTRTQRV
0 1
MPL (human) WVKNVFLNQTRTQRV N117
MPL (mouse) WVKNVSLnQTLIQRV N117-ng
MPL (rat) WVKNVFLNQTLMQRV N117
MPL (zebrafish) RVIDKDTNTTIYSRA N111
S531
LRHALWPSLPDLHRV
1 0
MPL (human) LRHALWPSLPDLHRV S531
MPL (mouse) LRHALWPsLPDLHRV S522-p
MPL (rat) LRHALWPSLPDLHRV S541
MPL (zebrafish) VKRSLWPPVPNLNKV P447
T546-p
LGQYLRDtAALSPPk
0 1
MPL (human) LGQYLRDtAALSPPk T546-p
MPL (mouse) LGQYLRDTAALsPsK T537
MPL (rat) LGQYLRDTAALSPSK T556
MPL (zebrafish) LENILTDISGSHWEP I462
S550
LRDtAALSPPkATVS
1 0
MPL (human) LRDtAALSPPkATVS S550
MPL (mouse) LRDTAALsPsKATVT S541-p
MPL (rat) LRDTAALSPSKATVT S560
MPL (zebrafish) LTDISGSHWEPTFNI H466
P552
DtAALSPPkATVSDT
1 0
MPL (human) DtAALSPPkATVSDT P552
MPL (mouse) DTAALsPsKATVTDs S543-p
MPL (rat) DTAALSPSKATVTDS S562
MPL (zebrafish) ISGSHWEPTFNIKQC P469
K553-ub
tAALSPPkATVSDTC
Upstream
Downstream
1 0
Effects on Modified Protein
  • protein degradation
Effects on Biological Processes:
  • cell growth, inhibited
Treatment
  • JAK_inhibitor_I
  • siRNA
  • TPO
MPL (human) tAALSPPkATVSDTC K553-ub
MPL (mouse) TAALsPsKATVTDsC K544
MPL (rat) TAALSPSKATVTDSC K563
MPL (zebrafish) SGSHWEPTFNIKQCD T470
T559
PkATVSDTCEEVEPS
1 0
MPL (human) PkATVSDTCEEVEPS T559
MPL (mouse) sKATVTDsCEEVEPS S550-p
MPL (rat) SKATVTDSCEEVEPS S569
MPL (zebrafish) PTFNIKQCDDDTATS C476
K573-ub
SLLEILPkSSERTPL
Upstream
Downstream
1 0
Effects on Modified Protein
  • protein degradation
Effects on Biological Processes:
  • cell growth, inhibited
Treatment
  • JAK_inhibitor_I
  • siRNA
  • TPO
MPL (human) SLLEILPkSSERTPL K573-ub
MPL (mouse) SLLEILPKssEstPL K564
MPL (rat) SLLEILPKSPERTPL K583
MPL (zebrafish) SVVEVLTEGESVVKT E490
S574
LLEILPkSSERTPLP
1 0
MPL (human) LLEILPkSSERTPLP S574
MPL (mouse) LLEILPKssEstPLP S565-p
MPL (rat) LLEILPKSPERTPLP S584
MPL (zebrafish) VVEVLTEGESVVKTC G491
S575
LEILPkSSERTPLPL
1 0
MPL (human) LEILPkSSERTPLPL S575
MPL (mouse) LEILPKssEstPLPL S566-p
MPL (rat) LEILPKSPERTPLPL P585
MPL (zebrafish) VEVLTEGESVVKTCK E492
R577
ILPkSSERTPLPLCS
1 0
MPL (human) ILPkSSERTPLPLCS R577
MPL (mouse) ILPKssEstPLPLCP S568-p
MPL (rat) ILPKSPERTPLPLCP R587
MPL (zebrafish) ESVVKTCKNTCPLLS K499
T578
LPkSSERTPLPLCSS
1 0
MPL (human) LPkSSERTPLPLCSS T578
MPL (mouse) LPKssEstPLPLCPS T569-p
MPL (rat) LPKSPERTPLPLCPS T588
MPL (zebrafish) SVVKTCKNTCPLLSE N500
Y591-p
SSQAQMDyRRLQPSC
Upstream
Downstream
5 18
Effects on Modified Protein
  • molecular association, regulation
  • phosphorylation
Effects on Biological Processes:
  • carcinogenesis, induced
  • cell differentiation, induced
  • signaling pathway regulation
Treatment
  • AK111
  • AK113
  • AK119
  • TPO
MPL (human) SSQAQMDyRRLQPSC Y591-p
MPL (mouse) PSQPQMDyRGLQPCL Y582-p
MPL (rat) PSQPQMDYRGLQPCL Y601
MPL (zebrafish) DLEMAQDYVILNNNI Y526
Y626-p
THIANHSyLPLSyWQ
Upstream
Downstream
11 2
MPL (human)
Y626-p
MPL (mouse)
Y616-p
MPL (rat)
Y635-p
Effects on Biological Processes:
  • carcinogenesis, induced
  • cell differentiation, induced
  • cell growth, induced
  • signaling pathway regulation
Treatment
  • AK111
  • AK113
  • AK119
  • PF4
  • TPO
MPL (human) THIANHSyLPLSyWQ Y626-p
MPL (mouse) THIANHSyLPLSyWQ Y616-p
MPL (rat) THIANHSYLPLSYWQ Y635
MPL (zebrafish) TDILNQSYLLLAEQS Y580
Y631-p
HSyLPLSyWQQP___
Upstream
Downstream
8 0
Effects on Modified Protein
  • molecular association, regulation
Effects on Biological Processes:
  • carcinogenesis, induced
  • cell differentiation, induced
  • signaling pathway regulation
Treatment
  • AK111
  • AK113
  • AK119
  • TPO
MPL (human) HSyLPLSyWQQP___ Y631-p
MPL (mouse) HSyLPLSyWQQP___ Y621-p
MPL (rat) HSYLPLSYWQQP___ Y640
MPL (zebrafish) QSYLLLAEQSDLETY E585