Other Species / Isoforms
  PIP5K1C (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
S11-p
EVPDEAEsAEAGAVP
0 1
PIP5K1C (human) EVPDEAEsAEAGAVP S11-p
PIP5K1C iso3 (human) EVPDEAESAEAGAVP S11
PIP5K1C (mouse) EVPDEAESAEAGAVT S11
PIP5K1C iso2 (mouse) EVPDEAESAEAGAVT S11
PIP5K1C (rat) EVPDEAESAEAGAVT S11
S11
EVPDEAESAEAGAVP
0 1
PIP5K1C (human) EVPDEAESAEAGAVP S11
PIP5K1C iso3 (human) EVPDEAESAEAGAVP S11
PIP5K1C (mouse) EVPDEAEsAEAGAVT S11-gl
PIP5K1C iso2 (mouse) EVPDEAESAEAGAVT S11
PIP5K1C (rat) EVPDEAESAEAGAVT S11
S45-p
AAPTEVLsMtAQPGP
0 1
PIP5K1C (human) AAPTEVLsMtAQPGP S45-p
PIP5K1C iso3 (human) AAPTEVLSMTAQPGP S45
PIP5K1C (mouse) AGLAEAPLVTGQPGP L45
PIP5K1C iso2 (mouse) AGLAEAPLVTGQPGP L45
PIP5K1C (rat) AILAEAPLVTGQPGP L45
T47-p
PTEVLsMtAQPGPGH
0 1
PIP5K1C (human) PTEVLsMtAQPGPGH T47-p
PIP5K1C iso3 (human) PTEVLSMTAQPGPGH T47
PIP5K1C (mouse) LAEAPLVTGQPGPGH T47
PIP5K1C iso2 (mouse) LAEAPLVTGQPGPGH T47
PIP5K1C (rat) LAEAPLVTGQPGPGH T47
K73-ub
SGETTYKkTTSSTLK
0 1
PIP5K1C (human) SGETTYKkTTSSTLK K73-ub
PIP5K1C iso3 (human) SGETTYKKTTSSTLK K73
PIP5K1C (mouse) SGETTYKKTTSSTLK K73
PIP5K1C iso2 (mouse) SGETTYKKTTSSTLK K73
PIP5K1C (rat) SGETTYKKTTSSTLK K73
K97-ub
TVGHLSSkPERDVLM
1 104
PIP5K1C (human) TVGHLSSkPERDVLM K97-ub
PIP5K1C iso3 (human) TVGHLSSKPERDVLM K97
PIP5K1C (mouse) TVGNLSSkPERDVLM K97-ub
PIP5K1C iso2 (mouse) TVGNLSSKPERDVLM K97
PIP5K1C (rat) TVGNLSSkPERDVLM K97-ub
Y136-p
QDFRFKTyAPVAFRY
0 9
PIP5K1C (human) QDFRFKTyAPVAFRY Y136-p
PIP5K1C iso3 (human) QDFRFKTYAPVAFRY Y136
PIP5K1C (mouse) QDFRFKTYAPVAFRY Y136
PIP5K1C iso2 (mouse) QDFRFKTYAPVAFRY Y136
PIP5K1C (rat) QDFRFKTyAPVAFRY Y136-p
K200-ub
KEAEFLQkLLPGYYM
0 7
PIP5K1C (human) KEAEFLQkLLPGYYM K200-ub
PIP5K1C iso3 (human) KEAEFLQKLLPGYYM K200
PIP5K1C (mouse) KEAEFLQkLLPGYYM K200-ub
PIP5K1C iso2 (mouse) KEAEFLQKLLPGYYM K200
PIP5K1C (rat) KEAEFLQkLLPGYYM K200-ub
T215-p
NLNQNPRtLLPKFYG
0 2
PIP5K1C (human) NLNQNPRtLLPKFYG T215-p
PIP5K1C iso3 (human) NLNQNPRTLLPKFYG T215
PIP5K1C (mouse) NLNQNPRTLLPKFYG T215
PIP5K1C iso2 (mouse) NLNQNPRTLLPKFYG T215
PIP5K1C (rat) NLNQNPRTLLPKFYG T215
S228-p
YGLYCVQsGGKNIRV
0 1
PIP5K1C (human) YGLYCVQsGGKNIRV S228-p
PIP5K1C iso3 (human) YGLYCVQSGGKNIRV S228
PIP5K1C (mouse) YGLYCVQSGGKNIRV S228
PIP5K1C iso2 (mouse) YGLYCVQSGGKNIRV S228
PIP5K1C (rat) YGLYCVQSGGKNIRV S228
K255-ub
MHLKFDLkGSTYKRR
Downstream
1 0
Effects on Modified Protein
  • protein degradation
  • ubiquitination
PIP5K1C (human) MHLKFDLkGSTYKRR K255-ub
PIP5K1C iso3 (human) MHLKFDLKGSTYKRR K255
PIP5K1C (mouse) MHLKFDLKGSTYKRR K255
PIP5K1C iso2 (mouse) MHLKFDLKGSTYKRR K255
PIP5K1C (rat) MHLKFDLKGSTYKRR K255
K270-ub
ASKKEKEkSFPTYKD
0 1
PIP5K1C (human) ASKKEKEkSFPTYKD K270-ub
PIP5K1C iso3 (human) ASKKEKEKSFPTYKD K270
PIP5K1C (mouse) ASKKEKEKSLPTYKD K270
PIP5K1C iso2 (mouse) ASKKEKEKSLPTYKD K270
PIP5K1C (rat) ASKKEKEKSLPTYkD K270
K276
EkSFPTYKDLDFMQD
0 1
PIP5K1C (human) EkSFPTYKDLDFMQD K276
PIP5K1C iso3 (human) EKSFPTYKDLDFMQD K276
PIP5K1C (mouse) EKSLPTYKDLDFMQD K276
PIP5K1C iso2 (mouse) EKSLPTYKDLDFMQD K276
PIP5K1C (rat) EKSLPTYkDLDFMQD K276-ub
T341-p
QAQGAQStSDEkRPV
0 1
PIP5K1C (human) QAQGAQStSDEkRPV T341-p
PIP5K1C iso3 (human) QAQGAQSTSDEKRPV T341
PIP5K1C (mouse) QAEGAQSKADEKRPV K341
PIP5K1C iso2 (mouse) QAEGAQSKAYRFIKK K341
PIP5K1C (rat) QAEGAQSKADEKRPV K341
K345-ub
AQStSDEkRPVGQkA
0 2
PIP5K1C (human) AQStSDEkRPVGQkA K345-ub
PIP5K1C iso3 (human) AQSTSDEKRPVGQKA K345
PIP5K1C (mouse) AQSKADEKRPVAQKA K345
PIP5K1C iso2 (mouse) gap -
PIP5K1C (rat) AQSKADEKRPVAQKA K345
K351-ub
EkRPVGQkALYSTAM
0 1
PIP5K1C (human) EkRPVGQkALYSTAM K351-ub
PIP5K1C iso3 (human) EKRPVGQKALYSTAM K351
PIP5K1C (mouse) EKRPVAQKALYSTAM K351
PIP5K1C iso2 (mouse) gap -
PIP5K1C (rat) EKRPVAQKALySTAR K351
Y354
PVGQkALYSTAMESI
0 1
PIP5K1C (human) PVGQkALYSTAMESI Y354
PIP5K1C iso3 (human) PVGQKALYSTAMESI Y354
PIP5K1C (mouse) PVAQKALYSTAMESI Y354
PIP5K1C iso2 (mouse) gap -
PIP5K1C (rat) PVAQKALySTARESI Y354-p
S402-p
GIIDILQsyRFIKkL
0 1
PIP5K1C (human) GIIDILQsyRFIKkL S402-p
PIP5K1C iso3 (human) GIIDILQSYRFIKKL S402
PIP5K1C (mouse) GIIDILQSYRFIKKL S402
PIP5K1C iso2 (mouse) gap -
PIP5K1C (rat) GIIDILQSYRFIKKL S402
Y403-p
IIDILQsyRFIKkLE
0 1
PIP5K1C (human) IIDILQsyRFIKkLE Y403-p
PIP5K1C iso3 (human) IIDILQSYRFIKKLE Y403
PIP5K1C (mouse) IIDILQSYRFIKKLE Y403
PIP5K1C iso2 (mouse) gap -
PIP5K1C (rat) IIDILQSYRFIKKLE Y403
K408-ub
QsyRFIKkLEHTWkA
0 1
PIP5K1C (human) QsyRFIKkLEHTWkA K408-ub
PIP5K1C iso3 (human) QSYRFIKKLEHTWKA K408
PIP5K1C (mouse) QSYRFIKKLEHTWKA K408
PIP5K1C iso2 (mouse) KAYRFIKKLEHTWKA K348
PIP5K1C (rat) QSYRFIKKLEHTWKA K408
K414-ub
KkLEHTWkALVHDGD
0 1
PIP5K1C (human) KkLEHTWkALVHDGD K414-ub
PIP5K1C iso3 (human) KKLEHTWKALVHDGD K414
PIP5K1C (mouse) KKLEHTWKALVHDGD K414
PIP5K1C iso2 (mouse) KKLEHTWKALVHDGD K354
PIP5K1C (rat) KKLEHTWKALVHDGD K414
N447
SNTVFRKNsSLKSsP
0 1
PIP5K1C (human) SNTVFRKNsSLKSsP N447
PIP5K1C iso3 (human) SNTVFRKNSSLKSSP N447
PIP5K1C (mouse) SSTVFRKsssLKssP S447-p
PIP5K1C iso2 (mouse) SSTVFRKSSSLKSSP S387
PIP5K1C (rat) SSTVFRKSSSLKSSP S447
S448-p
NTVFRKNsSLKSsPS
Upstream
Downstream
2 1
Effects on Modified Protein
  • enzymatic activity, inhibited
  • molecular association, regulation
Effects on Biological Processes:
  • carcinogenesis, altered
  • cell adhesion, induced
  • cell motility, altered
Kinase, in vitro:
  • PDK1 (human)
Putative in vivo kinases:
  • PDK1 (human)
  • PRKD1 (human)
Treatment
  • phorbol_ester
PIP5K1C (human) NTVFRKNsSLKSsPS S448-p
PIP5K1C iso3 (human) NTVFRKNSSLKSSPS S448
PIP5K1C (mouse) STVFRKsssLKssPS S448-p
PIP5K1C iso2 (mouse) STVFRKSSSLKSSPS S388
PIP5K1C (rat) STVFRKSSSLKSSPS S448
S449
TVFRKNsSLKSsPSK
0 2
PIP5K1C (human) TVFRKNsSLKSsPSK S449
PIP5K1C iso3 (human) TVFRKNSSLKSSPSK S449
PIP5K1C (mouse) TVFRKsssLKssPSK S449-p
PIP5K1C iso2 (mouse) TVFRKSSSLKSSPSK S389
PIP5K1C (rat) TVFRKSSSLKSSPSK S449
S452
RKNsSLKSsPSKKGr
0 1
PIP5K1C (human) RKNsSLKSsPSKKGr S452
PIP5K1C iso3 (human) RKNSSLKSSPSKKGR S452
PIP5K1C (mouse) RKsssLKssPSKkGr S452-p
PIP5K1C iso2 (mouse) RKSSSLKSSPSKKGR S392
PIP5K1C (rat) RKSSSLKSSPSKKGR S452
S453-p
KNsSLKSsPSKKGrG
Upstream
Downstream
1 3
Effects on Modified Protein
  • enzymatic activity, inhibited
Kinase, in vitro:
  • CDK5 (human)
Putative in vivo kinases:
  • CDK5 (human)
Treatment
  • EGF
  • HGF
  • SCF
  • seliciclib
  • TNF
PIP5K1C (human) KNsSLKSsPSKKGrG S453-p
PIP5K1C iso3 (human) KNSSLKSSPSKKGRG S453
PIP5K1C (mouse) KsssLKssPSKkGrG S453-p
PIP5K1C iso2 (mouse) KSSSLKSSPSKKGRG S393
PIP5K1C (rat) KSSSLKSSPSKKGRG S453
K457
LKSsPSKKGrGGALL
0 1
PIP5K1C (human) LKSsPSKKGrGGALL K457
PIP5K1C iso3 (human) LKSSPSKKGRGGALL K457
PIP5K1C (mouse) LKssPSKkGrGALLA K457-ac
PIP5K1C iso2 (mouse) LKSSPSKKGRGALLA K397
PIP5K1C (rat) LKSSPSKKGRGALLA K457
R459-m1
SsPSKKGrGGALLAV
0 4
PIP5K1C (human) SsPSKKGrGGALLAV R459-m1
PIP5K1C iso3 (human) SSPSKKGRGGALLAV R459
PIP5K1C (mouse) ssPSKkGrGALLAVK R459-m1
PIP5K1C iso2 (mouse) SSPSKKGRGALLAVK R399
PIP5K1C (rat) SSPSKKGRGALLAVK R459
R459
SsPSKKGRGGALLAV
0 3
PIP5K1C (human) SsPSKKGRGGALLAV R459
PIP5K1C iso3 (human) SSPSKKGRGGALLAV R459
PIP5K1C (mouse) ssPSKkGrGALLAVK R459-m2
PIP5K1C iso2 (mouse) SSPSKKGRGALLAVK R399
PIP5K1C (rat) SSPSKKGRGALLAVK R459
S476-p
LGPTAAFsASQIPSE
0 4
PIP5K1C (human) LGPTAAFsASQIPSE S476-p
PIP5K1C iso3 (human) LGPTAAFSASQIPSE S476
PIP5K1C (mouse) LGPTAAFsASQIPSE S475-p
PIP5K1C iso2 (mouse) LGPTAAFSASQIPSE S415
PIP5K1C (rat) LGPTAAFSASQIPSE S475
Y489-p
SEREEAQyDLRGARs
0 1
PIP5K1C (human) SEREEAQyDLRGARs Y489-p
PIP5K1C iso3 (human) SEREEAQYDLRGARS Y489
PIP5K1C (mouse) SEREDVQYDLRGARS Y488
PIP5K1C iso2 (mouse) SEREDVQYDLRGARS Y428
PIP5K1C (rat) SEREDVQYDLRGARS Y488
S496-p
yDLRGARsYPTLEDE
0 2
PIP5K1C (human) yDLRGARsYPTLEDE S496-p
PIP5K1C iso3 (human) YDLRGARSYPTLEDE S496
PIP5K1C (mouse) YDLRGARSYPTLEDE S495
PIP5K1C iso2 (mouse) YDLRGARSYPTLEDE S435
PIP5K1C (rat) YDLRGARSYPTLEDE S495
S539
SLSIPERSPsEtsEQ
0 1
PIP5K1C (human) SLSIPERSPsEtsEQ S539
PIP5K1C iso3 (human) SLSIPERSPSETSEQ S539
PIP5K1C (mouse) SLSIPERsPsDTsEQ S538-p
PIP5K1C iso2 (mouse) SLSIPERSPSDTSEQ S478
PIP5K1C (rat) SLSIPERSPSDTSEQ S538
S541-p
SIPERSPsEtsEQPR
0 4
PIP5K1C (human) SIPERSPsEtsEQPR S541-p
PIP5K1C iso3 (human) SIPERSPSETSEQPR S541
PIP5K1C (mouse) SIPERsPsDTsEQPR S540-p
PIP5K1C iso2 (mouse) SIPERSPSDTSEQPR S480
PIP5K1C (rat) SIPERSPSDTSEQPR S540
T543-p
PERSPsEtsEQPRYR
0 1
PIP5K1C (human) PERSPsEtsEQPRYR T543-p
PIP5K1C iso3 (human) PERSPSETSEQPRYR T543
PIP5K1C (mouse) PERsPsDTsEQPRYR T542
PIP5K1C iso2 (mouse) PERSPSDTSEQPRYR T482
PIP5K1C (rat) PERSPSDTSEQPRYR T542
S544-p
ERSPsEtsEQPRYRR
0 2
PIP5K1C (human) ERSPsEtsEQPRYRR S544-p
PIP5K1C iso3 (human) ERSPSETSEQPRYRR S544
PIP5K1C (mouse) ERsPsDTsEQPRYRR S543-p
PIP5K1C iso2 (mouse) ERSPSDTSEQPRYRR S483
PIP5K1C (rat) ERSPSDTSEQPRYRR S543
T553-p
QPRYRRRtQssGQDG
Upstream
Downstream
1 39
Effects on Modified Protein
  • intracellular localization
  • protein degradation
Effects on Biological Processes:
  • cell adhesion, induced
  • cell motility, induced
Kinase, in vitro:
  • p70S6K (human)
Putative in vivo kinases:
  • p70S6K (human)
Treatment
  • HGF
PIP5K1C (human) QPRYRRRtQssGQDG T553-p
PIP5K1C iso3 (human) QPRYRRRTQSSGQDG T553
PIP5K1C (mouse) QPRYRRRtQssGQDG T552-p
PIP5K1C iso2 (mouse) QPRYRRRTQSSGQDG T492
PIP5K1C (rat) QPRYRRRTQsSGQDG T552
S555-p
RYRRRtQssGQDGRP
Upstream
Downstream
2 37
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
  • protein degradation
Effects on Biological Processes:
  • cell adhesion, induced
  • cell motility, induced
  • cytoskeletal reorganization
Kinase, in vitro:
  • Akt1 (human)
  • Akt2 (human)
  • p70S6K (human)
Putative in vivo kinases:
  • Akt1 (human)
  • p70S6K (human)
Treatment
  • EGF
  • HGF
  • LY294002
  • MK-2206
  • siRNA
PIP5K1C (human) RYRRRtQssGQDGRP S555-p
PIP5K1C iso3 (human) RYRRRTQSSGQDGRP S555
PIP5K1C (mouse) RYRRRtQssGQDGRP S554-p
PIP5K1C iso2 (mouse) RYRRRTQSSGQDGRP S494
PIP5K1C (rat) RYRRRTQsSGQDGRP S554-p
S556-p
YRRRtQssGQDGRPQ
0 11
PIP5K1C (human) YRRRtQssGQDGRPQ S556-p
PIP5K1C iso3 (human) YRRRTQSSGQDGRPQ S556
PIP5K1C (mouse) YRRRtQssGQDGRPQ S555-p
PIP5K1C iso2 (mouse) YRRRTQSSGQDGRPQ S495
PIP5K1C (rat) YRRRTQsSGQDGRPQ S555
Y639-p
DAPATDIyFPTDERS
Upstream
Downstream
3 0
Effects on Biological Processes:
  • carcinogenesis, induced
  • cell growth, induced
  • cell motility, induced
Regulatory protein:
  • EGF (human)
  • HGF (human)
Treatment
  • EGF
  • HGF
PIP5K1C (human) DAPATDIyFPTDERS Y639-p
PIP5K1C iso3 (human) DAPATDIYFFTDGRY Y639
PIP5K1C (mouse) DAPSTDIyFPTDERS Y634-p
PIP5K1C iso2 (mouse) DAPSTDIYFFAHGRY Y574
PIP5K1C (rat) DAPSTDIYFFAHGRY Y635
-
gap
0 3
PIP5K1C (human) gap -
PIP5K1C iso3 (human) DGRYWIYSPRHRRLR S650
PIP5K1C (mouse) gap -
PIP5K1C iso2 (mouse) HGRYWLFsPRRRQLR S585-p
PIP5K1C (rat) HGRYWLFsPRRRRLR S646-p
Y649-p
TDERSWVysPLHYSA
Upstream
Downstream
6 0
Effects on Modified Protein
  • molecular association, regulation
  • phosphorylation
Kinase, in vitro:
  • Src (human)
Putative in vivo kinases:
  • Src (human)
Regulatory protein:
  • FAK (human)
Treatment
  • PP2
PIP5K1C (human) TDERSWVysPLHYSA Y649-p
PIP5K1C iso3 (human) gap -
PIP5K1C (mouse) TDERSWVysPLHYSA Y644-p
PIP5K1C iso2 (mouse) TDERSWVYSPLHYSA Y610
PIP5K1C (rat) TDGRSWVYSPLHYSA Y671
S650-p
DERSWVysPLHYSAQ
Upstream
Downstream
2 1
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
  • phosphorylation
Effects on Biological Processes:
  • cell adhesion, altered
  • cytoskeletal reorganization
Kinase, in vitro:
  • CDK1 (human)
  • CDK5 (human)
  • ERK1 (human)
Putative in vivo kinases:
  • CDK5 (human)
Treatment
  • butyrolactone
  • ciclosporin
  • depolarization
  • nocodazole
  • okadaic_acid
  • PD98059
  • seliciclib
PIP5K1C (human) DERSWVysPLHYSAQ S650-p
PIP5K1C iso3 (human) gap -
PIP5K1C (mouse) DERSWVysPLHYSAR S645-p
PIP5K1C iso2 (mouse) DERSWVYSPLHYSAR S611
PIP5K1C (rat) DGRSWVYSPLHYSAR S672
S662-p
SAQAPPAsDGESDT_
0 6
PIP5K1C (human) SAQAPPAsDGESDT_ S662-p
PIP5K1C iso3 (human) gap -
PIP5K1C (mouse) HYSARPAsDGEsDT_ S655-p
PIP5K1C iso2 (mouse) HYSARPASDGESDT_ S621
PIP5K1C (rat) HYSARPAsDGEsDt_ S682-p
S666
PPAsDGESDT_____
0 3
PIP5K1C (human) PPAsDGESDT_____ S666
PIP5K1C iso3 (human) gap -
PIP5K1C (mouse) RPAsDGEsDT_____ S659-p
PIP5K1C iso2 (mouse) RPASDGESDT_____ S625
PIP5K1C (rat) RPAsDGEsDt_____ S686-p
T668
AsDGESDT_______
0 1
PIP5K1C (human) AsDGESDT_______ T668
PIP5K1C iso3 (human) gap -
PIP5K1C (mouse) AsDGEsDT_______ T661
PIP5K1C iso2 (mouse) ASDGESDT_______ T627
PIP5K1C (rat) AsDGEsDt_______ T688-p