Other Species / Isoforms
  BACE (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
T47-p
GLRLPREtDEEPEEP
0 1
BACE (human) GLRLPREtDEEPEEP T47-p
BACE (mouse) GLRLPRETDEESEEP T47
BACE (rat) GLRLPRETDEEPEEP T47
S59-p
EEPGRRGsFVEMVDN
0 1
BACE (human) EEPGRRGsFVEMVDN S59-p
BACE (mouse) EEPGRRGSFVEMVDN S59
BACE (rat) EEPGRRGSFVEMVDN S59
S71-p
VDNLRGKsGQGYYVE
0 1
BACE (human) VDNLRGKsGQGYYVE S71-p
BACE (mouse) VDNLRGKSGQGYYVE S71
BACE (rat) VDNLRGKSGQGYYVE S71
S83-p
YVEMTVGsPPQTLNI
Upstream
1 0
Putative in vivo kinases:
  • P38A (human)
BACE (human) YVEMTVGsPPQTLNI S83-p
BACE (mouse) YVEMTVGSPPQTLNI S83
BACE (rat) YVEMTVGSPPQTLNI S83
K126-ac
STYRDLRkGVYVPYT
Downstream
1 2
Effects on Modified Protein
  • intracellular localization
  • protein stabilization
BACE (human) STYRDLRkGVYVPYT K126-ac
BACE (mouse) STYRDLRKGVYVPYT K126
BACE (rat) STYRDLRKSVYVPYT K126
K136-ac
YVPYTQGkWEGELGT
0 1
BACE (human) YVPYTQGkWEGELGT K136-ac
BACE (mouse) YVPYTQGKWEGELGT K136
BACE (rat) YVPYTQGKWEGELGT K136
N153
VSIPHGPNVTVRANI
0 1
BACE (human) VSIPHGPNVTVRANI N153
BACE (mouse) VSIPHGPnVTVRANI N153-ng
BACE (rat) VSIPHGPNVTVRANI N153
N172
ESDKFFINGSNWEGI
0 1
BACE (human) ESDKFFINGSNWEGI N172
BACE (mouse) ESDKFFInGSNWEGI N172-ng
BACE (rat) ESDKFFINGSNWEGI N172
S243
IIGGIDHSLYTGSLW
0 1
BACE (human) IIGGIDHSLYTGSLW S243
BACE (mouse) IIGGIDHsLyTGSLW S243-p
BACE (rat) IIGGIDHSLYTGSLW S243
Y245
GGIDHSLYTGSLWYt
0 1
BACE (human) GGIDHSLYTGSLWYt Y245
BACE (mouse) GGIDHsLyTGSLWYT Y245-p
BACE (rat) GGIDHSLYTGSLWYT Y245
T252-p
YTGSLWYtPIRREWY
Upstream
Downstream
1 0
Effects on Modified Protein
  • activity, induced
Kinase, in vitro:
  • CDK5 (human)
Putative in vivo kinases:
  • CDK5 (human)
Regulatory protein:
  • CDK5R1 (human)
Treatment
  • seliciclib
BACE (human) YTGSLWYtPIRREWY T252-p
BACE (mouse) yTGSLWYTPIRREWY T252
BACE (rat) YTGSLWYTPIRREWY T252
Y260-p
PIRREWYyEVIIVRV
0 1
BACE (human) PIRREWYyEVIIVRV Y260-p
BACE (mouse) PIRREWYYEVIIVRV Y260
BACE (rat) PIRREWYYEVIIVRV Y260
K275-ac
EINGQDLkMDCkEYN
Downstream
1 1
Effects on Modified Protein
  • intracellular localization
  • protein stabilization
BACE (human) EINGQDLkMDCkEYN K275-ac
BACE (mouse) EINGQDLKMDCKEYN K275
BACE (rat) EINGQDLKMDCKEYN K275
K279-ac
QDLkMDCkEYNYDkS
Downstream
1 1
Effects on Modified Protein
  • intracellular localization
  • protein stabilization
BACE (human) QDLkMDCkEYNYDkS K279-ac
BACE (mouse) QDLKMDCKEYNYDKS K279
BACE (rat) QDLKMDCKEYNYDKS K279
K285-ac
CkEYNYDkSIVDSGT
Downstream
1 1
Effects on Modified Protein
  • intracellular localization
  • protein stabilization
BACE (human) CkEYNYDkSIVDSGT K285-ac
BACE (mouse) CKEYNYDKSIVDSGT K285
BACE (rat) CKEYNYDKSIVDSGT K285
K285-ub
CkEYNYDkSIVDSGT
0 1
BACE (human) CkEYNYDkSIVDSGT K285-ub
BACE (mouse) CKEYNYDKSIVDSGT K285
BACE (rat) CKEYNYDKSIVDSGT K285
K299-ac
TTNLRLPkkVFEAAV
Downstream
1 1
Effects on Modified Protein
  • intracellular localization
  • protein stabilization
BACE (human) TTNLRLPkkVFEAAV K299-ac
BACE (mouse) TTNLRLPKKVFEAAV K299
BACE (rat) TTNLRLPKKVFEAAV K299
K300-ac
TNLRLPkkVFEAAVk
Downstream
1 1
Effects on Modified Protein
  • intracellular localization
  • protein stabilization
BACE (human) TNLRLPkkVFEAAVk K300-ac
BACE (mouse) TNLRLPKKVFEAAVK K300
BACE (rat) TNLRLPKKVFEAAVK K300
K300-ub
TNLRLPkkVFEAAVk
0 1
BACE (human) TNLRLPkkVFEAAVk K300-ub
BACE (mouse) TNLRLPKKVFEAAVK K300
BACE (rat) TNLRLPKKVFEAAVK K300
K307-ac
kVFEAAVksIKAASS
Downstream
1 1
Effects on Modified Protein
  • intracellular localization
  • protein stabilization
BACE (human) kVFEAAVksIKAASS K307-ac
BACE (mouse) KVFEAAVKSIKAASS K307
BACE (rat) KVFEAAVKSIKAASS K307
S308-p
VFEAAVksIKAASST
0 1
BACE (human) VFEAAVksIKAASST S308-p
BACE (mouse) VFEAAVKSIKAASST S308
BACE (rat) VFEAAVKSIKAASST S308
S498-p
DDFADDIsLLk____
Upstream
Downstream
6 4
Effects on Modified Protein
  • enzymatic activity, induced
  • intracellular localization
Kinase, in vitro:
  • CK1A (human)
  • CK1D (human)
  • ROCK2 (human)
Regulatory protein:
  • PAR3 (human)
Treatment
  • CK1-7
  • okadaic_acid
  • PKC-theta_pseudosubstrate
BACE (human) DDFADDIsLLk____ S498-p
BACE (mouse) DDFADDIsLLK____ S498-p
BACE (rat) DDFADDISLLK____ S498
K501-ub
ADDIsLLk_______
Downstream
3 0
Effects on Modified Protein
  • intracellular localization
  • protein degradation
BACE (human) ADDIsLLk_______ K501-ub
BACE (mouse) ADDIsLLK_______ K501
BACE (rat) ADDISLLK_______ K501