S12-p
|
KSKPKDAsQRRRsLE
|
Upstream
|
|
5
|
2
|
|
|
Treatment
- bradykinin
- EGF
- FGF1
- FGF2
- insulin
- PDGF
- phorbol_ester
- serum
- vanadate
- vasopressin
|
|
Src (human)
|
KSKPKDAsQRRRsLE
|
S12-p
|
Src iso2 (human)
|
KSKPKDASQRRRSLE
|
S12
|
Src (mouse)
|
KSKPKDAsQRRRsLE
|
S12-p
|
Src iso1 (mouse)
|
KSKPKDAsQRRRsLE
|
S12-p
|
Src (rat)
|
KSKPKDASQRRRsLE
|
S12
|
Src (chicken)
|
KSKPKDPsQRRRsLE
|
S12-p
|
|
S17-p
|
DAsQRRRsLEPSENV
|
Upstream
|
|
10
|
58
|
|
|
|
|
Src (human)
|
DAsQRRRsLEPAENV
|
S17-p
|
Src iso2 (human)
|
DASQRRRSLEPAENV
|
S17
|
Src (mouse)
|
DAsQRRRsLEPSENV
|
S17-p
|
Src iso1 (mouse)
|
DAsQRRRsLEPsENV
|
S17-p
|
Src (rat)
|
DASQRRRsLEPAENV
|
S17-p
|
Src (chicken)
|
DPsQRRRsLEPPDST
|
S17-p
|
|
S21
|
RRRsLEPSENVHGAG
|
|
|
0
|
7
|
|
|
Src (human)
|
RRRsLEPAENVHGAG
|
A21
|
Src iso2 (human)
|
RRRSLEPAENVHGAG
|
A21
|
Src (mouse)
|
RRRsLEPSENVHGAG
|
S21
|
Src iso1 (mouse)
|
RRRsLEPsENVHGAG
|
S21-p
|
Src (rat)
|
RRRsLEPAENVHGAG
|
A21
|
Src (chicken)
|
RRRsLEPPDSTHHGG
|
P21
|
|
S34
|
AGGAFPASQTPSKPA
|
|
|
1
|
2
|
|
|
Src (human)
|
GGGAFPAsQtPsKPA
|
S35-p
|
Src iso2 (human)
|
GGGAFPASQTPSKPA
|
S35
|
Src (mouse)
|
AGGAFPASQTPSKPA
|
S34
|
Src iso1 (mouse)
|
AGGAFPAsQTPSKPA
|
S34-p
|
Src (rat)
|
AGGAFPASQTPSKPA
|
S34
|
Src (chicken)
|
HHGGFPASQtPNKTA
|
S32
|
|
T36
|
GAFPASQTPSKPASA
|
|
|
3
|
1
|
|
|
Src (human)
|
GAFPAsQtPsKPAsA
|
T37-p
|
Src iso2 (human)
|
GAFPASQTPSKPASA
|
T37
|
Src (mouse)
|
GAFPASQTPSKPASA
|
T36
|
Src iso1 (mouse)
|
GAFPAsQTPSKPASA
|
T36
|
Src (rat)
|
GAFPASQTPSKPASA
|
T36
|
Src (chicken)
|
GGFPASQtPNKTAAP
|
T34-p
|
|
S38
|
FPASQTPSKPASADG
|
|
|
1
|
1
|
|
|
Src (human)
|
FPAsQtPsKPAsAdG
|
S39-p
|
Src iso2 (human)
|
FPASQTPSKPASADG
|
S39
|
Src (mouse)
|
FPASQTPSKPASADG
|
S38
|
Src iso1 (mouse)
|
FPAsQTPSKPASADG
|
S38
|
Src (rat)
|
FPASQTPSKPASADG
|
S38
|
Src (chicken)
|
FPASQtPNKTAAPDT
|
N36
|
|
S42
|
QTPSKPASADGHRGP
|
|
|
2
|
1
|
|
|
Src (human)
|
QtPsKPAsAdGHRGP
|
S43-p
|
Src iso2 (human)
|
QTPSKPASADGHRGP
|
S43
|
Src (mouse)
|
QTPSKPASADGHRGP
|
S42
|
Src iso1 (mouse)
|
QTPSKPASADGHRGP
|
S42
|
Src (rat)
|
QTPSKPASADGHRGP
|
S42
|
Src (chicken)
|
QtPNKTAAPDTHRtP
|
A40
|
|
D44
|
PSKPASADGHRGPSA
|
|
|
0
|
1
|
|
|
Src (human)
|
PsKPAsAdGHRGPsA
|
D45-ca
|
Src iso2 (human)
|
PSKPASADGHRGPSA
|
D45
|
Src (mouse)
|
PSKPASADGHRGPSA
|
D44
|
Src iso1 (mouse)
|
PSKPASADGHRGPSA
|
D44
|
Src (rat)
|
PSKPASADGHRGPNA
|
D44
|
Src (chicken)
|
PNKTAAPDTHRtPsR
|
D42
|
|
G48
|
ASADGHRGPSAAFVP
|
|
|
2
|
0
|
|
|
Src (human)
|
AsAdGHRGPsAAFAP
|
G49
|
Src iso2 (human)
|
ASADGHRGPSAAFAP
|
G49
|
Src (mouse)
|
ASADGHRGPSAAFVP
|
G48
|
Src iso1 (mouse)
|
ASADGHRGPSAAFVP
|
G48
|
Src (rat)
|
ASADGHRGPNAAFVP
|
G48
|
Src (chicken)
|
AAPDTHRtPsRSFGT
|
T46-p
|
|
S50
|
ADGHRGPSAAFVPPA
|
|
|
3
|
3
|
|
|
Src (human)
|
AdGHRGPsAAFAPAA
|
S51-p
|
Src iso2 (human)
|
ADGHRGPSAAFAPAA
|
S51
|
Src (mouse)
|
ADGHRGPSAAFVPPA
|
S50
|
Src iso1 (mouse)
|
ADGHRGPSAAFVPPA
|
S50
|
Src (rat)
|
ADGHRGPNAAFVPPA
|
N50
|
Src (chicken)
|
PDTHRtPsRSFGTVA
|
S48-p
|
|
K61
|
VPPAAEPKLFGGFNS
|
|
|
0
|
1
|
|
|
Src (human)
|
APAAAEPkLFGGFNs
|
K62-ac
|
Src iso2 (human)
|
APAAAEPKLFGGFNS
|
K62
|
Src (mouse)
|
VPPAAEPKLFGGFNS
|
K61
|
Src iso1 (mouse)
|
VPPAAEPKLFGGFNS
|
K61
|
Src (rat)
|
PPAAAEPKLFGGFNS
|
K62
|
Src (chicken)
|
GTVATEPKLFGGFNT
|
K59
|
|
S68
|
KLFGGFNSSDTVTsP
|
|
|
0
|
4
|
|
|
Src (human)
|
kLFGGFNssDtVtsP
|
S69-p
|
Src iso2 (human)
|
KLFGGFNSSDTVTSP
|
S69
|
Src (mouse)
|
KLFGGFNSSDTVTsP
|
S68
|
Src iso1 (mouse)
|
KLFGGFNSSDtVTsP
|
S68
|
Src (rat)
|
KLFGGFNSSDTVTsP
|
S69
|
Src (chicken)
|
KLFGGFNTSDTVTsP
|
T66
|
|
S69
|
LFGGFNSSDTVTsPQ
|
|
|
1
|
2
|
|
|
Src (human)
|
LFGGFNssDtVtsPQ
|
S70-p
|
Src iso2 (human)
|
LFGGFNSSDTVTSPQ
|
S70
|
Src (mouse)
|
LFGGFNSSDTVTsPQ
|
S69
|
Src iso1 (mouse)
|
LFGGFNSSDtVTsPQ
|
S69
|
Src (rat)
|
LFGGFNSSDTVTsPQ
|
S70
|
Src (chicken)
|
LFGGFNTSDTVTsPQ
|
S67
|
|
T71
|
GGFNSSDTVTsPQRA
|
|
|
0
|
2
|
|
|
Src (human)
|
GGFNssDtVtsPQRA
|
T72-p
|
Src iso2 (human)
|
GGFNSSDTVTSPQRA
|
T72
|
Src (mouse)
|
GGFNSSDTVTsPQRA
|
T71
|
Src iso1 (mouse)
|
GGFNSSDtVTsPQRA
|
T71-p
|
Src (rat)
|
GGFNSSDTVTsPQRA
|
T72
|
Src (chicken)
|
GGFNTSDTVTsPQRA
|
T69
|
|
T73
|
FNSSDTVTsPQRAGP
|
|
|
0
|
2
|
|
|
Src (human)
|
FNssDtVtsPQRAGP
|
T74-p
|
Src iso2 (human)
|
FNSSDTVTSPQRAGP
|
T74
|
Src (mouse)
|
FNSSDTVTsPQRAGP
|
T73
|
Src iso1 (mouse)
|
FNSSDtVTsPQRAGP
|
T73
|
Src (rat)
|
FNSSDTVTsPQRAGP
|
T74
|
Src (chicken)
|
FNTSDTVTsPQRAGA
|
T71
|
|
S74-p
|
NSSDTVTsPQRAGPL
|
Upstream
|
Downstream
|
9
|
27
|
|
|
Effects on Biological Processes:
- cell differentiation, induced
- transcription, induced
|
|
Regulatory protein:
|
Treatment
|
|
Src (human)
|
NssDtVtsPQRAGPL
|
S75-p
|
Src iso2 (human)
|
NSSDTVTSPQRAGPL
|
S75
|
Src (mouse)
|
NSSDTVTsPQRAGPL
|
S74-p
|
Src iso1 (mouse)
|
NSSDtVTsPQRAGPL
|
S74-p
|
Src (rat)
|
NSSDTVTsPQRAGPL
|
S75-p
|
Src (chicken)
|
NTSDTVTsPQRAGAL
|
S72-p
|
|
Y92-p
|
VTTFVALyDYESRTE
|
|
|
1
|
4
|
|
|
Src (human)
|
VTTFVALyDyEsRTE
|
Y93-p
|
Src iso2 (human)
|
VTTFVALYDYESRTE
|
Y93
|
Src (mouse)
|
VTTFVALyDYESRTE
|
Y92-p
|
Src iso1 (mouse)
|
VTTFVALyDYESRtE
|
Y92-p
|
Src (rat)
|
VTTFVALYDYESRTE
|
Y93
|
Src (chicken)
|
VTTFVALYDYESRTE
|
Y90
|
|
Y94
|
TFVALyDYESRTETD
|
|
|
0
|
1
|
|
|
Src (human)
|
TFVALyDyEsRTETD
|
Y95-p
|
Src iso2 (human)
|
TFVALYDYESRTETD
|
Y95
|
Src (mouse)
|
TFVALyDYESRTETD
|
Y94
|
Src iso1 (mouse)
|
TFVALyDYESRtEtD
|
Y94
|
Src (rat)
|
TFVALYDYESRTETD
|
Y95
|
Src (chicken)
|
TFVALYDYESRTETD
|
Y92
|
|
S96
|
VALyDYESRTETDLS
|
|
|
1
|
0
|
|
|
Src (human)
|
VALyDyEsRTETDLs
|
S97-p
|
Src iso2 (human)
|
VALYDYESRTETDLS
|
S97
|
Src (mouse)
|
VALyDYESRTETDLS
|
S96
|
Src iso1 (mouse)
|
VALyDYESRtEtDLs
|
S96
|
Src (rat)
|
VALYDYESRTETDLS
|
S97
|
Src (chicken)
|
VALYDYESRTETDLS
|
S94
|
|
T98
|
LyDYESRTETDLSFK
|
|
|
0
|
1
|
|
|
Src (human)
|
LyDyEsRTETDLsFK
|
T99
|
Src iso2 (human)
|
LYDYESRTETDLSFK
|
T99
|
Src (mouse)
|
LyDYESRTETDLSFK
|
T98
|
Src iso1 (mouse)
|
LyDYESRtEtDLsFK
|
T98-p
|
Src (rat)
|
LYDYESRTETDLSFK
|
T99
|
Src (chicken)
|
LYDYESRTETDLSFK
|
T96
|
|
T100
|
DYESRTETDLSFKKG
|
|
|
0
|
1
|
|
|
Src (human)
|
DyEsRTETDLsFKKG
|
T101
|
Src iso2 (human)
|
DYESRTETDLSFKKG
|
T101
|
Src (mouse)
|
DYESRTETDLSFKKG
|
T100
|
Src iso1 (mouse)
|
DYESRtEtDLsFKKG
|
T100-p
|
Src (rat)
|
DYESRTETDLSFKKG
|
T101
|
Src (chicken)
|
DYESRTETDLSFKKG
|
T98
|
|
S103
|
SRTETDLSFKKGERL
|
|
|
1
|
5
|
|
|
Src (human)
|
sRTETDLsFKKGERL
|
S104-p
|
Src iso2 (human)
|
SRTETDLSFKKGERL
|
S104
|
Src (mouse)
|
SRTETDLSFKKGERL
|
S103
|
Src iso1 (mouse)
|
SRtEtDLsFKKGERL
|
S103-p
|
Src (rat)
|
SRTETDLSFKKGERL
|
S104
|
Src (chicken)
|
SRTETDLSFKKGERL
|
S101
|
|
T116
|
RLQIVNNTEGDWWLA
|
|
|
0
|
1
|
|
|
Src (human)
|
RLQIVNNtEGDWWLA
|
T117-p
|
Src iso2 (human)
|
RLQIVNNTRKVDVRE
|
T117
|
Src (mouse)
|
RLQIVNNTEGDWWLA
|
T116
|
Src iso1 (mouse)
|
RLQIVNNTRKVDVRE
|
T116
|
Src (rat)
|
RLQIVNNTEGDWWLA
|
T117
|
Src (chicken)
|
RLQIVNNTEGDWWLA
|
T114
|
|
S127
|
WWLAHSLSTGQTGyI
|
|
|
0
|
1
|
|
|
Src (human)
|
WWLAHSLstGQtGyI
|
S128-p
|
Src iso2 (human)
|
WWLAHSLSTGQTGYI
|
S134
|
Src (mouse)
|
WWLAHSLSTGQTGyI
|
S127
|
Src iso1 (mouse)
|
WWLAHSLSTGQTGYI
|
S133
|
Src (rat)
|
WWLAHSLSTGQTGYI
|
S128
|
Src (chicken)
|
WWLAHSLTTGQTGYI
|
T125
|
|
T128
|
WLAHSLSTGQTGyIP
|
|
|
0
|
1
|
|
|
Src (human)
|
WLAHSLstGQtGyIP
|
T129-p
|
Src iso2 (human)
|
WLAHSLSTGQTGYIP
|
T135
|
Src (mouse)
|
WLAHSLSTGQTGyIP
|
T128
|
Src iso1 (mouse)
|
WLAHSLSTGQTGYIP
|
T134
|
Src (rat)
|
WLAHSLSTGQTGYIP
|
T129
|
Src (chicken)
|
WLAHSLTTGQTGYIP
|
T126
|
|
T131
|
HSLSTGQTGyIPSNy
|
|
|
0
|
1
|
|
|
Src (human)
|
HSLstGQtGyIPSNy
|
T132-p
|
Src iso2 (human)
|
HSLSTGQTGYIPSNY
|
T138
|
Src (mouse)
|
HSLSTGQTGyIPSNy
|
T131
|
Src iso1 (mouse)
|
HSLSTGQTGYIPSNY
|
T137
|
Src (rat)
|
HSLSTGQTGYIPSNY
|
T132
|
Src (chicken)
|
HSLTTGQTGYIPSNY
|
T129
|
|
Y133-p
|
LSTGQTGyIPSNyVA
|
|
Downstream
|
1
|
1
|
|
|
Effects on Biological Processes:
- cell cycle regulation
- cell growth, altered
|
|
Src (human)
|
LstGQtGyIPSNyVA
|
Y134-p
|
Src iso2 (human)
|
LSTGQTGYIPSNYVA
|
Y140
|
Src (mouse)
|
LSTGQTGyIPSNyVA
|
Y133-p
|
Src iso1 (mouse)
|
LSTGQTGYIPSNYVA
|
Y139
|
Src (rat)
|
LSTGQTGYIPSNYVA
|
Y134
|
Src (chicken)
|
LTTGQTGYIPSNYVA
|
Y131
|
|
Y138-p
|
TGyIPSNyVAPSDSI
|
Upstream
|
Downstream
|
2
|
1
|
|
|
Effects on Biological Processes:
- cell cycle regulation
- cell growth, altered
|
|
Kinase, in vitro:
|
Putative in vivo kinases:
|
Treatment
|
|
Src (human)
|
tGyIPSNyVAPSDSI
|
Y139-p
|
Src iso2 (human)
|
TGYIPSNYVAPSDSI
|
Y145
|
Src (mouse)
|
TGyIPSNyVAPSDSI
|
Y138-p
|
Src iso1 (mouse)
|
TGYIPSNYVAPSDSI
|
Y144
|
Src (rat)
|
TGYIPSNYVAPSDSI
|
Y139
|
Src (chicken)
|
TGYIPSNYVAPSDSI
|
Y136
|
|
Y151
|
SIQAEEWYFGKITRR
|
|
|
0
|
1
|
|
|
Src (human)
|
SIQAEEWyFGKITRR
|
Y152-p
|
Src iso2 (human)
|
SIQAEEWYFGKITRR
|
Y158
|
Src (mouse)
|
SIQAEEWYFGKITRR
|
Y151
|
Src iso1 (mouse)
|
SIQAEEWYFGKITRR
|
Y157
|
Src (rat)
|
SIQAEEWYFGKITRR
|
Y152
|
Src (chicken)
|
SIQAEEWYFGKITRR
|
Y149
|
|
T173
|
NAENPRGTFLVRESE
|
|
|
0
|
1
|
|
|
Src (human)
|
NAENPRGtFLVRESE
|
T174-p
|
Src iso2 (human)
|
NAENPRGTFLVRESE
|
T180
|
Src (mouse)
|
NAENPRGTFLVRESE
|
T173
|
Src iso1 (mouse)
|
NAENPRGTFLVRESE
|
T179
|
Src (rat)
|
NAENPRGTFLVRESE
|
T174
|
Src (chicken)
|
NPENPRGTFLVRESE
|
T171
|
|
T181
|
FLVRESETTKGAYCL
|
|
|
0
|
5
|
|
|
Src (human)
|
FLVRESEttKGAyCL
|
T182-p
|
Src iso2 (human)
|
FLVRESETTKGAYCL
|
T188
|
Src (mouse)
|
FLVRESETTKGAYCL
|
T181
|
Src iso1 (mouse)
|
FLVRESETtKGAyCL
|
T187
|
Src (rat)
|
FLVRESETTKGAyCL
|
T182
|
Src (chicken)
|
FLVRESETTKGAYCL
|
T179
|
|
T182
|
LVRESETTKGAYCLS
|
|
|
0
|
15
|
|
|
Src (human)
|
LVRESEttKGAyCLS
|
T183-p
|
Src iso2 (human)
|
LVRESETTKGAYCLS
|
T189
|
Src (mouse)
|
LVRESETTKGAYCLS
|
T182
|
Src iso1 (mouse)
|
LVRESETtKGAyCLS
|
T188-p
|
Src (rat)
|
LVRESETTKGAyCLS
|
T183
|
Src (chicken)
|
LVRESETTKGAYCLS
|
T180
|
|
Y186
|
SETTKGAYCLSVSDF
|
|
|
0
|
60
|
|
|
Src (human)
|
SEttKGAyCLSVSDF
|
Y187-p
|
Src iso2 (human)
|
SETTKGAYCLSVSDF
|
Y193
|
Src (mouse)
|
SETTKGAYCLSVSDF
|
Y186
|
Src iso1 (mouse)
|
SETtKGAyCLSVSDF
|
Y192-p
|
Src (rat)
|
SETTKGAyCLSVSDF
|
Y187-p
|
Src (chicken)
|
SETTKGAYCLSVSDF
|
Y184
|
|
Y215
|
KLDSGGFYITSRTQF
|
|
|
8
|
25
|
|
|
Src (human)
|
KLDSGGFyITSRTQF
|
Y216-p
|
Src iso2 (human)
|
KLDSGGFYITSRTQF
|
Y222
|
Src (mouse)
|
KLDSGGFYITSRTQF
|
Y215
|
Src iso1 (mouse)
|
KLDSGGFyITSRTQF
|
Y221-p
|
Src (rat)
|
KLDSGGFyITSRTQF
|
Y216-p
|
Src (chicken)
|
KLDSGGFYITSRTQF
|
Y213
|
|
Y231
|
SLQQLVAYYSKHADG
|
|
|
0
|
15
|
|
|
Src (human)
|
SLQQLVAyySKHADG
|
Y232-p
|
Src iso2 (human)
|
SLQQLVAYYSKHADG
|
Y238
|
Src (mouse)
|
SLQQLVAYYSKHADG
|
Y231
|
Src iso1 (mouse)
|
SLQQLVAyYSKHADG
|
Y237-p
|
Src (rat)
|
SLQQLVAyYSKHADG
|
Y232-p
|
Src (chicken)
|
SLQQLVAYYSKHADG
|
Y229
|
|
Y232
|
LQQLVAYYSKHADGL
|
|
|
0
|
1
|
|
|
Src (human)
|
LQQLVAyySKHADGL
|
Y233-p
|
Src iso2 (human)
|
LQQLVAYYSKHADGL
|
Y239
|
Src (mouse)
|
LQQLVAYYSKHADGL
|
Y232
|
Src iso1 (mouse)
|
LQQLVAyYSKHADGL
|
Y238
|
Src (rat)
|
LQQLVAyYSKHADGL
|
Y233
|
Src (chicken)
|
LQQLVAYYSKHADGL
|
Y230
|
|
T245
|
GLCHRLTTVCPTSKP
|
|
|
0
|
1
|
|
|
Src (human)
|
GLCHRLTtVCPtSKP
|
T246-p
|
Src iso2 (human)
|
GLCHRLTTVCPTSKP
|
T252
|
Src (mouse)
|
GLCHRLTTVCPTSKP
|
T245
|
Src iso1 (mouse)
|
GLCHRLTTVCPTSKP
|
T251
|
Src (rat)
|
GLCHRLTTVCPTSkP
|
T246
|
Src (chicken)
|
GLCHRLTNVCPTSKP
|
N243
|
|
T249
|
RLTTVCPTSKPQTQG
|
|
|
0
|
1
|
|
|
Src (human)
|
RLTtVCPtSKPQTQG
|
T250-p
|
Src iso2 (human)
|
RLTTVCPTSKPQTQG
|
T256
|
Src (mouse)
|
RLTTVCPTSKPQTQG
|
T249
|
Src iso1 (mouse)
|
RLTTVCPTSKPQTQG
|
T255
|
Src (rat)
|
RLTTVCPTSkPQTQG
|
T250
|
Src (chicken)
|
RLTNVCPTSKPQTQG
|
T247
|
|
K251
|
TTVCPTSKPQTQGLA
|
|
|
0
|
1
|
|
|
Src (human)
|
TtVCPtSKPQTQGLA
|
K252
|
Src iso2 (human)
|
TTVCPTSKPQTQGLA
|
K258
|
Src (mouse)
|
TTVCPTSKPQTQGLA
|
K251
|
Src iso1 (mouse)
|
TTVCPTSKPQTQGLA
|
K257
|
Src (rat)
|
TTVCPTSkPQTQGLA
|
K252-ub
|
Src (chicken)
|
TNVCPTSKPQTQGLA
|
K249
|
|
T287
|
FGEVWMGTWNGTTRV
|
|
|
0
|
1
|
|
|
Src (human)
|
FGEVWMGtWNGTTRV
|
T288-p
|
Src iso2 (human)
|
FGEVWMGTWNGTTRV
|
T294
|
Src (mouse)
|
FGEVWMGTWNGTTRV
|
T287
|
Src iso1 (mouse)
|
FGEVWMGTWNGTTRV
|
T293
|
Src (rat)
|
FGEVWMGTWNGTTRV
|
T288
|
Src (chicken)
|
FGEVWMGTWNGTTRV
|
T285
|
|
K297
|
GTTRVAIKTLKPGTM
|
|
|
1
|
0
|
|
|
Src (human)
|
GTTRVAIkTLKPGtM
|
K298-ub
|
Src iso2 (human)
|
GTTRVAIKTLKPGTM
|
K304
|
Src (mouse)
|
GTTRVAIKTLKPGTM
|
K297
|
Src iso1 (mouse)
|
GTTRVAIKTLKPGTM
|
K303
|
Src (rat)
|
GTTRVAIKTLKPGTM
|
K298
|
Src (chicken)
|
GTTRVAIKTLKPGTM
|
K295
|
|
T303
|
IKTLKPGTMSPEAFL
|
|
|
0
|
2
|
|
|
Src (human)
|
IkTLKPGtMsPEAFL
|
T304-p
|
Src iso2 (human)
|
IKTLKPGTMSPEAFL
|
T310
|
Src (mouse)
|
IKTLKPGTMSPEAFL
|
T303
|
Src iso1 (mouse)
|
IKTLKPGTMSPEAFL
|
T309
|
Src (rat)
|
IKTLKPGTMSPEAFL
|
T304
|
Src (chicken)
|
IKTLKPGTMSPEAFL
|
T301
|
|
S305
|
TLKPGTMSPEAFLQE
|
|
|
0
|
2
|
|
|
Src (human)
|
TLKPGtMsPEAFLQE
|
S306-p
|
Src iso2 (human)
|
TLKPGTMSPEAFLQE
|
S312
|
Src (mouse)
|
TLKPGTMSPEAFLQE
|
S305
|
Src iso1 (mouse)
|
TLKPGTMSPEAFLQE
|
S311
|
Src (rat)
|
TLKPGTMSPEAFLQE
|
S306
|
Src (chicken)
|
TLKPGTMSPEAFLQE
|
S303
|
|
Y337
|
VVSEEPIYIVTEYMN
|
|
|
1
|
3
|
|
|
Src (human)
|
VVSEEPIyIVTEyMS
|
Y338-p
|
Src iso2 (human)
|
VVSEEPIYIVTEYMS
|
Y344
|
Src (mouse)
|
VVSEEPIYIVTEYMN
|
Y337
|
Src iso1 (mouse)
|
VVSEEPIyIVTEYMN
|
Y343-p
|
Src (rat)
|
VVSEEPIYIVTEYMN
|
Y338
|
Src (chicken)
|
VVSEEPIYIVTEYMS
|
Y335
|
|
Y342
|
PIYIVTEYMNKGSLL
|
|
|
0
|
1
|
|
|
Src (human)
|
PIyIVTEyMSKGSLL
|
Y343-p
|
Src iso2 (human)
|
PIYIVTEYMSKGSLL
|
Y349
|
Src (mouse)
|
PIYIVTEYMNKGSLL
|
Y342
|
Src iso1 (mouse)
|
PIyIVTEYMNKGSLL
|
Y348
|
Src (rat)
|
PIYIVTEYMNKGSLL
|
Y343
|
Src (chicken)
|
PIYIVTEYMSKGSLL
|
Y340
|
|
Y378
|
QIASGMAYVERMNYV
|
|
|
0
|
1
|
|
|
Src (human)
|
QIASGMAyVERMNyV
|
Y379-p
|
Src iso2 (human)
|
QIASGMAYVERMNYV
|
Y385
|
Src (mouse)
|
QIASGMAYVERMNYV
|
Y378
|
Src iso1 (mouse)
|
QIASGMAYVERMNYV
|
Y384
|
Src (rat)
|
QIASGMAYVERMNYV
|
Y379
|
Src (chicken)
|
QIASGMAYVERMNYV
|
Y376
|
|
Y384
|
AYVERMNYVHRDLRA
|
|
|
0
|
2
|
|
|
Src (human)
|
AyVERMNyVHRDLRA
|
Y385-p
|
Src iso2 (human)
|
AYVERMNYVHRDLRA
|
Y391
|
Src (mouse)
|
AYVERMNYVHRDLRA
|
Y384
|
Src iso1 (mouse)
|
AYVERMNYVHRDLRA
|
Y390
|
Src (rat)
|
AYVERMNYVHRDLRA
|
Y385
|
Src (chicken)
|
AYVERMNYVHRDLRA
|
Y382
|
|
Y418-p
|
RLIEDNEyTARQGAK
|
Upstream
|
Downstream
|
452
|
3133
|
|
|
|
Effects on Modified Protein
- activity, induced
- enzymatic activity, induced
- phosphorylation
- protein degradation
- receptor internalization, induced
- ubiquitination
|
Effects on Biological Processes:
- autophagy, induced
- autophagy, inhibited
- cell adhesion, induced
- cell differentiation, induced
- cell growth, induced
- endocytosis, induced
- neural plasticity
- signaling pathway regulation
- transcription, induced
|
|
Phosphatases, in vitro:
|
Putative upstream phosphatases:
|
Regulatory protein:
- ADAMTSL3 (human)
- AGTRAP (human)
- beclin 1 (human)
- BVR (human)
- CASK (human)
- caveolin-1 (mouse)
- CFD (human)
- FAK (mouse)
- MTSS1 (human)
- MYH6 (mouse)
- PAG (rat)
- PGK1 (human)
- PIK3C3 (human)
- PLA2G5 (human)
- PSTPIP2 (human)
- PTPRD (human)
- THY1 (human)
|
Treatment
- angiotensin_2
- antibody
- atorvastatin
- calorie_restriction
- cholesterol
- dasatinib
- eCF506
- ethanol
- exercise training
- high-fat diet
- high_glucose
- ischemia/reperfusion
- isoflurane
- long-term_potentiation
- LY294002
- MCAO/R
- naloxone
- palmitate
- phorbol_ester
- PP1
- PP2
- pyrintegrin
- restraint stress
- saracatinib
- SB 366791
- sevoflurane
- Silica
- SKI-606
- SNAP
- SU6656
- TGF-beta
- thapsigargin
|
|
Src (human)
|
RLIEDNEytARQGAk
|
Y419-p
|
Src iso2 (human)
|
RLIEDNEYTARQGAK
|
Y425
|
Src (mouse)
|
RLIEDNEyTARQGAK
|
Y418-p
|
Src iso1 (mouse)
|
RLIEDNEytARQGAK
|
Y424-p
|
Src (rat)
|
RLIEDNEyTARQGAk
|
Y419-p
|
Src (chicken)
|
RLIEDNEyTARQGAK
|
Y416-p
|
|
T419
|
LIEDNEyTARQGAKF
|
|
|
0
|
24
|
|
|
Src (human)
|
LIEDNEytARQGAkF
|
T420-p
|
Src iso2 (human)
|
LIEDNEYTARQGAKF
|
T426
|
Src (mouse)
|
LIEDNEyTARQGAKF
|
T419
|
Src iso1 (mouse)
|
LIEDNEytARQGAKF
|
T425-p
|
Src (rat)
|
LIEDNEyTARQGAkF
|
T420
|
Src (chicken)
|
LIEDNEyTARQGAKF
|
T417
|
|
K425
|
yTARQGAKFPIKWTA
|
|
|
1
|
2
|
|
|
Src (human)
|
ytARQGAkFPIkWTA
|
K426-ac
|
Src iso2 (human)
|
YTARQGAKFPIKWTA
|
K432
|
Src (mouse)
|
yTARQGAKFPIKWTA
|
K425
|
Src iso1 (mouse)
|
ytARQGAKFPIKWTA
|
K431
|
Src (rat)
|
yTARQGAkFPIKWTA
|
K426-ac
|
Src (chicken)
|
yTARQGAKFPIKWTA
|
K423
|
|
K429
|
QGAKFPIKWTAPEAA
|
|
|
1
|
1
|
|
|
Src (human)
|
QGAkFPIkWTAPEAA
|
K430-ac
|
Src iso2 (human)
|
QGAKFPIKWTAPEAA
|
K436
|
Src (mouse)
|
QGAKFPIKWTAPEAA
|
K429
|
Src iso1 (mouse)
|
QGAKFPIKWTAPEAA
|
K435
|
Src (rat)
|
QGAkFPIKWTAPEAA
|
K430
|
Src (chicken)
|
QGAKFPIKWTAPEAA
|
K427
|
|
Y438-p
|
TAPEAALyGRFTIKS
|
Upstream
|
|
1
|
545
|
|
|
Regulatory protein:
|
Treatment
|
|
Src (human)
|
TAPEAALyGRFTIKS
|
Y439-p
|
Src iso2 (human)
|
TAPEAALYGRFTIKS
|
Y445
|
Src (mouse)
|
TAPEAALyGRFTIKS
|
Y438-p
|
Src iso1 (mouse)
|
TAPEAALyGRFTIKS
|
Y444-p
|
Src (rat)
|
TAPEAALyGRFTIKS
|
Y439-p
|
Src (chicken)
|
TAPEAALYGRFTIKS
|
Y436
|
|
Y465
|
TTKGRVPYPGMVNRE
|
|
|
0
|
1
|
|
|
Src (human)
|
TTKGRVPyPGMVNRE
|
Y466-p
|
Src iso2 (human)
|
TTKGRVPYPGMVNRE
|
Y472
|
Src (mouse)
|
TTKGRVPYPGMVNRE
|
Y465
|
Src iso1 (mouse)
|
TTKGRVPYPGMVNRE
|
Y471
|
Src (rat)
|
TTKGRVPYPGMVNRE
|
Y466
|
Src (chicken)
|
TTKGRVPYPGMVNRE
|
Y463
|
|
Y481
|
LDQVERGYRMPCPPE
|
|
|
0
|
1
|
|
|
Src (human)
|
LDQVERGyRMPCPPE
|
Y482-p
|
Src iso2 (human)
|
LDQVERGYRMPCPPE
|
Y488
|
Src (mouse)
|
LDQVERGYRMPCPPE
|
Y481
|
Src iso1 (mouse)
|
LDQVERGYRMPCPPE
|
Y487
|
Src (rat)
|
LDQVERGYRMPCPPE
|
Y482
|
Src (chicken)
|
LDQVERGYRMPCPPE
|
Y479
|
|
S492
|
CPPECPESLHDLMCQ
|
|
|
1
|
0
|
|
|
Src (human)
|
CPPECPEsLHDLMCQ
|
S493-p
|
Src iso2 (human)
|
CPPECPESLHDLMCQ
|
S499
|
Src (mouse)
|
CPPECPESLHDLMCQ
|
S492
|
Src iso1 (mouse)
|
CPPECPESLHDLMCQ
|
S498
|
Src (rat)
|
CPPECPESLHDLMCQ
|
S493
|
Src (chicken)
|
CPPECPESLHDLMCQ
|
S490
|
|
Y521
|
LQAFLEDYFTSTEPQ
|
|
|
8
|
0
|
|
|
Src (human)
|
LQAFLEDyFTstEPQ
|
Y522-p
|
Src iso2 (human)
|
LQAFLEDYFTSTEPQ
|
Y528
|
Src (mouse)
|
LQAFLEDYFTSTEPQ
|
Y521
|
Src iso1 (mouse)
|
LQAFLEDyFTSTEPQ
|
Y527-p
|
Src (rat)
|
LQAFLEDYFTSTEPQ
|
Y522
|
Src (chicken)
|
LQAFLEDyFTSTEPQ
|
Y519-p
|
|
S524
|
FLEDYFTSTEPQyQP
|
|
|
0
|
1
|
|
|
Src (human)
|
FLEDyFTstEPQyQP
|
S525-p
|
Src iso2 (human)
|
FLEDYFTSTEPQYQP
|
S531
|
Src (mouse)
|
FLEDYFTSTEPQyQP
|
S524
|
Src iso1 (mouse)
|
FLEDyFTSTEPQyQP
|
S530
|
Src (rat)
|
FLEDYFTSTEPQyQP
|
S525
|
Src (chicken)
|
FLEDyFTSTEPQyQP
|
S522
|
|
T525
|
LEDYFTSTEPQyQPG
|
|
|
0
|
2
|
|
|
Src (human)
|
LEDyFTstEPQyQPG
|
T526-p
|
Src iso2 (human)
|
LEDYFTSTEPQYQPG
|
T532
|
Src (mouse)
|
LEDYFTSTEPQyQPG
|
T525
|
Src iso1 (mouse)
|
LEDyFTSTEPQyQPG
|
T531
|
Src (rat)
|
LEDYFTSTEPQyQPG
|
T526
|
Src (chicken)
|
LEDyFTSTEPQyQPG
|
T523
|
|
Y529-p
|
FTSTEPQyQPGENL_
|
Upstream
|
Downstream
|
151
|
989
|
|
|
|
Effects on Modified Protein
- enzymatic activity, inhibited
|
Effects on Biological Processes:
- cell differentiation, altered
- cell differentiation, inhibited
|
|
Phosphatases, in vitro:
|
Putative upstream phosphatases:
|
Regulatory protein:
- caveolin-1 (mouse)
- CSK (mouse)
- MTSS1 (human)
- PTPRD (human)
|
Treatment
|
|
Src (human)
|
FTstEPQyQPGENL_
|
Y530-p
|
Src iso2 (human)
|
FTSTEPQYQPGENL_
|
Y536
|
Src (mouse)
|
FTSTEPQyQPGENL_
|
Y529-p
|
Src iso1 (mouse)
|
FTSTEPQyQPGENL_
|
Y535-p
|
Src (rat)
|
FTSTEPQyQPGENL_
|
Y530-p
|
Src (chicken)
|
FTSTEPQyQPGENL_
|
Y527-p
|
|