Other Species / Isoforms
  NRF2 (mouse)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

  HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
S40-p
SREVFDFsQRQKDYE
Upstream
Downstream
33 0
Effects on Modified Protein
  • activity, induced
  • intracellular localization
  • molecular association, regulation
  • protein stabilization
  • ubiquitination
Effects on Biological Processes:
  • carcinogenesis, induced
  • transcription, induced
Kinase, in vitro:
  • PKCA (mouse)
Putative in vivo kinases:
  • PKCA (mouse)
  • PKCD (human)
  • PKCD (mouse)
view more >
Regulatory protein:
  • ALKBH8 (mouse)
  • EGFR (mouse)
  • PKCA (mouse)
  • PKCE (mouse)
  • PKCH (mouse)
  • SHANK3 (human)
view more >
Treatment
  • AG1478
  • astragaloside_IV
  • Dihydrotanshinone
  • Go_6850
  • Go_6976
  • Go_6983
  • H2O2
  • MK-2206
  • phorbol_ester
  • rotenone
  • rottlerin
  • siRNA
  • staurosporine
  • stiff ECM substrate
  • sulforaphane
  • tBHQ
view more >
NRF2 (human) SREVFDFsQRRkEYE S40-p
NRF2 (mouse) SREVFDFsQRQKDYE S40-p
NRF2 (rat) SREVFDFsQRQKDYE S40-p
K44
FDFsQRQKDYELEKQ
1 1
NRF2 (human) FDFsQRRkEYELEkQ K44-ub
NRF2 (mouse) FDFsQRQKDYELEKQ K44
NRF2 (rat) FDFsQRQKDYELEKQ K44
K50
QKDYELEKQKKLEKE
1 0
NRF2 (human) RkEYELEkQkkLEkE K50-ub
NRF2 (mouse) QKDYELEKQKKLEKE K50
NRF2 (rat) QKDYELEKQKKLEKE K50
K52
DYELEKQKKLEKERQ
1 0
NRF2 (human) EYELEkQkkLEkERQ K52-ub
NRF2 (mouse) DYELEKQKKLEKERQ K52
NRF2 (rat) DYELEKQKKLEKERQ K52
K53
YELEKQKKLEKERQE
1 0
NRF2 (human) YELEkQkkLEkERQE K53-ub
NRF2 (mouse) YELEKQKKLEKERQE K53
NRF2 (rat) YELEKQKKLEKERQE K53
K56
EKQKKLEKERQEQLQ
1 0
NRF2 (human) EkQkkLEkERQEQLQ K56-ub
NRF2 (mouse) EKQKKLEKERQEQLQ K56
NRF2 (rat) EKQKKLEKERQEQLQ K56
K64
ERQEQLQKEQEKAFF
1 2
NRF2 (human) ERQEQLQkEQEkAFF K64-ub
NRF2 (mouse) ERQEQLQKEQEKAFF K64
NRF2 (rat) ERQEQLQKEQEKAFF K64
K68
QLQKEQEKAFFAQFQ
1 0
NRF2 (human) QLQkEQEkAFFAQLQ K68-ub
NRF2 (mouse) QLQKEQEKAFFAQFQ K68
NRF2 (rat) QLQKEQEKAFFAQLQ K68
K110
SQVAHIPKQDALYFE
2 1
NRF2 (human) SQVAHIPkSDALYFD K110-sm
NRF2 (mouse) SQVAHIPKQDALYFE K110
NRF2 (rat) SQVAHIPKQDALYFE K110
S207
ADTTAVPSPEATLTE
2 7
NRF2 (human) VETTMVPsPEAKLTE S215-p
NRF2 (mouse) ADTTAVPSPEATLTE S207
NRF2 (rat) AETTTVPSPEATLTE S214
S227
HFYSSISSLEKEVGN
0 1
NRF2 (human) HFYSSIPsMEKEVGN S234-p
NRF2 (mouse) HFYSSISSLEKEVGN S227
NRF2 (rat) HFYSSIPSLEKEVDS S234
G236
EKEVGNCGPHFLHGF
0 1
NRF2 (human) EKEVGNCsPHFLNAF S243-p
NRF2 (mouse) EKEVGNCGPHFLHGF G236
NRF2 (rat) EKEVDSCSPHFLHGF S243
S292
SDGGSMPSSAAISQS
0 1
NRF2 (human) SISNSMPsPATLSHS S301-p
NRF2 (mouse) SDGGSMPSSAAISQS S292
NRF2 (rat) SGGGSMPSSAAISQS S299
S335-p
MEFNDSDsGIsLNTs
Upstream
Downstream
4 1
Effects on Modified Protein
  • activity, inhibited
  • molecular association, regulation
  • protein degradation
Effects on Biological Processes:
  • carcinogenesis, induced
Kinase, in vitro:
  • GSK3B (human)
  • GSK3B (mouse)
Putative in vivo kinases:
  • GSK3B (human)
  • GSK3B (mouse)
Treatment
  • SB216763
  • siRNA
NRF2 (human) AEFNDSDsGIsLNTs S344-p
NRF2 (mouse) MEFNDSDsGIsLNTs S335-p
NRF2 (rat) VEFNDSDSGISLNTS S342
S338-p
NDSDsGIsLNTsPSR
Upstream
Downstream
4 1
Effects on Modified Protein
  • activity, inhibited
  • molecular association, regulation
  • protein degradation
Effects on Biological Processes:
  • carcinogenesis, induced
Kinase, in vitro:
  • GSK3B (human)
  • GSK3B (mouse)
Putative in vivo kinases:
  • GSK3B (human)
  • GSK3B (mouse)
Treatment
  • SB216763
  • siRNA
NRF2 (human) NDSDsGIsLNTsPSV S347-p
NRF2 (mouse) NDSDsGIsLNTsPSR S338-p
NRF2 (rat) NDSDSGISLNTSPSR S345
S342-p
sGIsLNTsPSRAsPE
Upstream
Downstream
3 1
Effects on Modified Protein
  • molecular association, regulation
  • protein degradation
Kinase, in vitro:
  • GSK3B (mouse)
Putative in vivo kinases:
  • GSK3B (mouse)
Treatment
  • siRNA
NRF2 (human) sGIsLNTsPSVAsPE S351-p
NRF2 (mouse) sGIsLNTsPSRAsPE S342-p
NRF2 (rat) SGISLNTSPSRASPE S349
S347-p
NTsPSRAsPEHsVES
Upstream
Downstream
3 1
Effects on Modified Protein
  • molecular association, regulation
  • protein degradation
Kinase, in vitro:
  • GSK3B (mouse)
Putative in vivo kinases:
  • GSK3B (mouse)
Treatment
  • siRNA
NRF2 (human) NTsPSVAsPEHSVES S356-p
NRF2 (mouse) NTsPSRAsPEHsVES S347-p
NRF2 (rat) NTSPSRASPEHSVES S354
S351-p
SRAsPEHsVESsIYG
Upstream
Downstream
1 0
Effects on Modified Protein
  • molecular association, regulation
  • protein degradation
Kinase, in vitro:
  • GSK3B (mouse)
Putative in vivo kinases:
  • GSK3B (mouse)
Treatment
  • siRNA
NRF2 (human) SVAsPEHSVESSSYG S360
NRF2 (mouse) SRAsPEHsVESsIYG S351-p
NRF2 (rat) SRASPEHSVESSIYG S358
S355-p
PEHsVESsIYGDPPP
Upstream
Downstream
1 0
Effects on Modified Protein
  • molecular association, regulation
  • protein degradation
Kinase, in vitro:
  • GSK3B (mouse)
Putative in vivo kinases:
  • GSK3B (mouse)
Treatment
  • siRNA
NRF2 (human) PEHSVESSSYGDtLL S364
NRF2 (mouse) PEHsVESsIYGDPPP S355-p
NRF2 (rat) PEHSVESSIYGDPPP S362
P360
ESsIYGDPPPGFsDS
1 0
NRF2 (human) ESSSYGDtLLGLsDs T369-p
NRF2 (mouse) ESsIYGDPPPGFsDS P360
NRF2 (rat) ESSIYGDPPPGFSDS P367
S365-p
GDPPPGFsDSEMEEL
2 2
NRF2 (human) GDtLLGLsDsEVEEL S374-p
NRF2 (mouse) GDPPPGFsDSEMEEL S365-p
NRF2 (rat) GDPPPGFSDSEMEEL S372
S367
PPPGFsDSEMEELDS
0 1
NRF2 (human) tLLGLsDsEVEELDS S376-p
NRF2 (mouse) PPPGFsDSEMEELDS S367
NRF2 (rat) PPPGFSDSEMEELDS S374
A386
VKQNGPKAQPAHSPG
1 0
NRF2 (human) VKQNGPKtPVHSSGD T395-p
NRF2 (mouse) VKQNGPKAQPAHSPG A386
NRF2 (rat) VKQNGPKAQPTHSSG A393
S400-p
GDTVQPLsPAQGHSA
4 5
NRF2 (human) GDMVQPLsPSQGQST S408-p
NRF2 (mouse) GDTVQPLsPAQGHSA S400-p
NRF2 (rat) GDTVQPLSPAQGHSA S407
T417
RESQCENTTKKEVPV
0 1
NRF2 (human) HDAQCENtPEKELPV T425-p
NRF2 (mouse) RESQCENTTKKEVPV T417
NRF2 (rat) HESQCENTTKKEVPV T424
S425-p
TKKEVPVsPGHQKAP
3 6
NRF2 (human) PEKELPVsPGHrktP S433-p
NRF2 (mouse) TKKEVPVsPGHQKAP S425-p
NRF2 (rat) TKKEVPVSPGHQKVP S432
Q429
VPVsPGHQKAPFTKD
1 0
NRF2 (human) LPVsPGHrktPFTkD R437-me
NRF2 (mouse) VPVsPGHQKAPFTKD Q429
NRF2 (rat) VPVSPGHQKVPFTKD Q436
K430
PVsPGHQKAPFTKDK
1 1
NRF2 (human) PVsPGHrktPFTkDk K438-ac
NRF2 (mouse) PVsPGHQKAPFTKDK K430
NRF2 (rat) PVSPGHQKVPFTKDK K437
A431
VsPGHQKAPFTKDKH
1 0
NRF2 (human) VsPGHrktPFTkDkH T439-p
NRF2 (mouse) VsPGHQKAPFTKDKH A431
NRF2 (rat) VSPGHQKVPFTKDKH V438
K435
HQKAPFTKDKHSSRL
1 1
NRF2 (human) HrktPFTkDkHsSRL K443-ac
NRF2 (mouse) HQKAPFTKDKHSSRL K435
NRF2 (rat) HQKVPFTKDKHSSRL K442
K437
KAPFTKDKHSSRLEA
1 1
NRF2 (human) ktPFTkDkHsSRLEA K445-ac
NRF2 (mouse) KAPFTKDKHSSRLEA K437
NRF2 (rat) KVPFTKDKHSSRLEA K444
S439
PFTKDKHSSRLEAHL
0 1
NRF2 (human) PFTkDkHsSRLEAHL S447-p
NRF2 (mouse) PFTKDKHSSRLEAHL S439
NRF2 (rat) PFTKDKHSSRLEAHL S446
K454
TRDELRAKALHIPFP
1 1
NRF2 (human) TRDELRAkALHIPFP K462-ac
NRF2 (mouse) TRDELRAKALHIPFP K454
NRF2 (rat) TRDELRAKALHIPFP K461
K454
TRDELRAKALHIPFP
0 1
NRF2 (human) TRDELRAkALHIPFP K462-ub
NRF2 (mouse) TRDELRAKALHIPFP K454
NRF2 (rat) TRDELRAKALHIPFP K461
K464
HIPFPVEKIINLPVD
1 1
NRF2 (human) HIPFPVEkIINLPVV K472-ac
NRF2 (mouse) HIPFPVEKIINLPVD K464
NRF2 (rat) HIPFPVEKIINLPVD K471
K479
DFNEMMSKEQFNEAQ
1 1
NRF2 (human) DFNEMMSkEQFNEAQ K487-ac
NRF2 (mouse) DFNEMMSKEQFNEAQ K479
NRF2 (rat) DFNEMMSKEQFNEAQ K486
K498
RDIRRRGKNKVAAQN
1 1
NRF2 (human) RDIRRRGkNkVAAQN K506-ac
NRF2 (mouse) RDIRRRGKNKVAAQN K498
NRF2 (rat) RDIRRRGKNKVAAQN K505
K500
IRRRGKNKVAAQNCR
1 1
NRF2 (human) IRRRGkNkVAAQNCR K508-ac
NRF2 (mouse) IRRRGKNKVAAQNCR K500
NRF2 (rat) IRRRGKNKVAAQNCR K507
K508
VAAQNCRKRKLENIV
1 1
NRF2 (human) VAAQNCRkRkLENIV K516-ac
NRF2 (mouse) VAAQNCRKRKLENIV K508
NRF2 (rat) VAAQNCRKRKLENIV K515
K508
VAAQNCRKRKLENIV
0 1
NRF2 (human) VAAQNCRkRkLENIV K516-ub
NRF2 (mouse) VAAQNCRKRKLENIV K508
NRF2 (rat) VAAQNCRKRKLENIV K515
K510
AQNCRKRKLENIVEL
1 1
NRF2 (human) AQNCRkRkLENIVEL K518-ac
NRF2 (mouse) AQNCRKRKLENIVEL K510
NRF2 (rat) AQNCRKRKLENIVEL K517
K510
AQNCRKRKLENIVEL
0 1
NRF2 (human) AQNCRkRkLENIVEL K518-ub
NRF2 (mouse) AQNCRKRKLENIVEL K510
NRF2 (rat) AQNCRKRKLENIVEL K517
K510
AQNCRKRKLENIVEL
0 1
NRF2 (human) AQNCRkRkLENIVEL K518-sm
NRF2 (mouse) AQNCRKRKLENIVEL K510
NRF2 (rat) AQNCRKRKLENIVEL K517
K525
EQDLGHLKDEREKLL
1 1
NRF2 (human) EQDLDHLkDEkEkLL K533-ac
NRF2 (mouse) EQDLGHLKDEREKLL K525
NRF2 (rat) EQDLGHLKDEREKLL K532
R528
LGHLKDEREKLLREK
1 1
NRF2 (human) LDHLkDEkEkLLkEk K536-ac
NRF2 (mouse) LGHLKDEREKLLREK R528
NRF2 (rat) LGHLKDEREKLLREK R535
K530
HLKDEREKLLREKGE
1 1
NRF2 (human) HLkDEkEkLLkEkGE K538-ac
NRF2 (mouse) HLKDEREKLLREKGE K530
NRF2 (rat) HLKDEREKLLREKGE K537
R533
DEREKLLREKGENDR
1 1
NRF2 (human) DEkEkLLkEkGENDk K541-ac
NRF2 (mouse) DEREKLLREKGENDR R533
NRF2 (rat) DEREKLLREKGENDR R540
K535
REKLLREKGENDRNL
1 1
NRF2 (human) kEkLLkEkGENDkSL K543-ac
NRF2 (mouse) REKLLREKGENDRNL K535
NRF2 (rat) REKLLREKGENDRNL K542
R540
REKGENDRNLHLLKR
1 1
NRF2 (human) kEkGENDkSLHLLkk K548-ac
NRF2 (mouse) REKGENDRNLHLLKR R540
NRF2 (rat) REKGENDRNLHLLKR R547
R540
REKGENDRNLHLLKR
0 1
NRF2 (human) kEkGENDkSLHLLkk K548-ub
NRF2 (mouse) REKGENDRNLHLLKR R540
NRF2 (rat) REKGENDRNLHLLKR R547
K546
DRNLHLLKRRLsTLY
1 1
NRF2 (human) DkSLHLLkkQLstLy K554-ac
NRF2 (mouse) DRNLHLLKRRLsTLY K546
NRF2 (rat) DRNLHLLKRKLSTLY K553
K546
DRNLHLLKRRLsTLY
0 1
NRF2 (human) DkSLHLLkkQLstLy K554-ub
NRF2 (mouse) DRNLHLLKRRLsTLY K546
NRF2 (rat) DRNLHLLKRKLSTLY K553
R547
RNLHLLKRRLsTLYL
1 1
NRF2 (human) kSLHLLkkQLstLyL K555-ac
NRF2 (mouse) RNLHLLKRRLsTLYL R547
NRF2 (rat) RNLHLLKRKLSTLYL R554
S550-p
HLLKRRLsTLYLEVF
Upstream
Downstream
3 2
Effects on Modified Protein
  • intracellular localization
Effects on Biological Processes:
  • transcription, induced
Kinase, in vitro:
  • AMPKA1 (human)
NRF2 (human) HLLkkQLstLyLEVF S558-p
NRF2 (mouse) HLLKRRLsTLYLEVF S550-p
NRF2 (rat) HLLKRKLSTLYLEVF S557
T551
LLKRRLsTLYLEVFS
1 1
NRF2 (human) LLkkQLstLyLEVFS T559-p
NRF2 (mouse) LLKRRLsTLYLEVFS T551
NRF2 (rat) LLKRKLSTLYLEVFS T558
Y553
KRRLsTLYLEVFSML
0 2
NRF2 (human) kkQLstLyLEVFSML Y561-p
NRF2 (mouse) KRRLsTLYLEVFSML Y553
NRF2 (rat) KRKLSTLYLEVFSML Y560
K566
MLRDEDGKPySPSEY
0 1
NRF2 (human) MLRDEDGkPysPSEY K574-ub
NRF2 (mouse) MLRDEDGKPySPSEY K566
NRF2 (rat) MLRDEDGKPYSPSEY K573
Y568-p
RDEDGKPySPSEYSL
Upstream
Downstream
5 2
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
  • protein degradation
  • ubiquitination
Putative in vivo kinases:
  • Fyn (mouse)
Treatment
  • H2O2
  • lithium
  • PP2
  • tBHQ
view more >
NRF2 (human) RDEDGkPysPSEYSL Y576-p
NRF2 (mouse) RDEDGKPySPSEYSL Y568-p
NRF2 (rat) RDEDGKPYSPSEYSL Y575
S569
DEDGKPySPSEYSLQ
2 2
NRF2 (human) DEDGkPysPSEYSLQ S577-p
NRF2 (mouse) DEDGKPySPSEYSLQ S569
NRF2 (rat) DEDGKPYSPSEYSLQ S576
K588
GNVFLVPKSKKPDTK
1 0
NRF2 (human) GNVFLVPkSKkPDVK K596-ac
NRF2 (mouse) GNVFLVPKSKKPDTK K588
NRF2 (rat) GNVFLVPKSKKPDTK K595
K591
FLVPKSKKPDTKKN_
1 0
NRF2 (human) FLVPkSKkPDVKKN_ K599-ac
NRF2 (mouse) FLVPKSKKPDTKKN_ K591
NRF2 (rat) FLVPKSKKPDTKKN_ K598