Other Species / Isoforms
  P130Cas (rat)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
-
gap
0 1
P130Cas (human) gap -
P130Cas iso2 (human) EAEQRGRTPGPSFEW T15
P130Cas iso6 (human) gap -
P130Cas iso7 (human) PLAAPRPtPKDPCLR T15-p
P130Cas iso8 (human) gap -
P130Cas (mouse) gap -
P130Cas (rat) gap -
P130Cas iso2 (rat) gap -
-
gap
0 1
P130Cas (human) ______MNHLNVLAK N2
P130Cas iso2 (human) gap -
P130Cas iso6 (human) gap -
P130Cas iso7 (human) gap -
P130Cas iso8 (human) ______MsVPNVLAK S2-p
P130Cas (mouse) ______MTVPNVLAK T2
P130Cas (rat) gap -
P130Cas iso2 (rat) gap -
Y106
NVLAKALYDNVAESP
1 3
P130Cas (human) NVLAKALyDNVAEsP Y12-p
P130Cas iso2 (human) NVLAKALYDNVAESP Y30
P130Cas iso6 (human) NVLAKALYDNVAESP Y58
P130Cas iso7 (human) NVLAKALYDNVAESP Y30
P130Cas iso8 (human) NVLAKALYDNVAEsP Y12
P130Cas (mouse) NVLAKALyDNVAESP Y12-p
P130Cas (rat) NVLAKALYDNVAESP Y106
P130Cas iso2 (rat) NVLAKALYDNVAESP Y12
S112
LYDNVAESPDELSFR
0 1
P130Cas (human) LyDNVAEsPDELSFR S18-p
P130Cas iso2 (human) LYDNVAESPDELSFR S36
P130Cas iso6 (human) LYDNVAESPDELSFR S64
P130Cas iso7 (human) LYDNVAESPDELSFR S36
P130Cas iso8 (human) LYDNVAEsPDELSFR S18-p
P130Cas (mouse) LyDNVAESPDELSFR S18
P130Cas (rat) LYDNVAESPDELSFR S112
P130Cas iso2 (rat) LYDNVAESPDELSFR S18
Y161
LKILVGMYDKKPAAP
0 2
P130Cas (human) LKILVGMyDKKPAGP Y67-p
P130Cas iso2 (human) LKILVGMYDKKPAGP Y85
P130Cas iso6 (human) LKILVGMYDKKPAGP Y113
P130Cas iso7 (human) LKILVGMYDKKPAGP Y85
P130Cas iso8 (human) LKILVGMYDKKPAGP Y67
P130Cas (mouse) LKILVGMYDKKPVGP Y67
P130Cas (rat) LKILVGMYDKKPAAP Y161
P130Cas iso2 (rat) LKILVGMYDKKPAAP Y67
N211
AYQPQPDNVYLVPTP
0 2
P130Cas (human) TYQPQPDsVyLVPTP S113-p
P130Cas iso2 (human) TYQPQPDSVYLVPTP S131
P130Cas iso6 (human) TYQPQPDSVYLVPTP S159
P130Cas iso7 (human) TYQPQPDSVYLVPTP S131
P130Cas iso8 (human) TYQPQPDSVYLVPTP S113
P130Cas (mouse) AYQPQSDNVyLVPTP N117
P130Cas (rat) AYQPQPDNVYLVPTP N211
P130Cas iso2 (rat) AYQPQPDNVYLVPTP N117
Y213
QPQPDNVYLVPTPSK
0 22
P130Cas (human) QPQPDsVyLVPTPSK Y115-p
P130Cas iso2 (human) QPQPDSVYLVPTPSK Y133
P130Cas iso6 (human) QPQPDSVYLVPTPSK Y161
P130Cas iso7 (human) QPQPDSVYLVPTPSK Y133
P130Cas iso8 (human) QPQPDSVYLVPTPSK Y115
P130Cas (mouse) QPQSDNVyLVPTPSK Y119-p
P130Cas (rat) QPQPDNVYLVPTPSK Y213
P130Cas iso2 (rat) QPQPDNVYLVPTPSK Y119
Y226-p
SKTQQGLyQAPGPNP
Upstream
4 819
Kinase, in vitro:
  • Src (chicken)
P130Cas (human) SKAQQGLyQVPGPsP Y128-p
P130Cas iso2 (human) SKAQQGLYQVPGPSP Y146
P130Cas iso6 (human) SKAQQGLYQVPGPSP Y174
P130Cas iso7 (human) SKAQQGLYQVPGPSP Y146
P130Cas iso8 (human) SKAQQGLYQVPGPSP Y128
P130Cas (mouse) SKTQQGLyQAPGPNP Y132-p
P130Cas (rat) SKTQQGLyQAPGPNP Y226-p
P130Cas iso2 (rat) SKTQQGLyQAPGPNP Y132-p
N232
LyQAPGPNPQFQSPP
0 6
P130Cas (human) LyQVPGPsPQFQsPP S134-p
P130Cas iso2 (human) LYQVPGPSPQFQSPP S152
P130Cas iso6 (human) LYQVPGPSPQFQSPP S180
P130Cas iso7 (human) LYQVPGPSPQFQSPP S152
P130Cas iso8 (human) LYQVPGPSPQFQSPP S134
P130Cas (mouse) LyQAPGPNPQFQsPP N138
P130Cas (rat) LyQAPGPNPQFQSPP N232
P130Cas iso2 (rat) LyQAPGPNPQFQsPP N138
S237
GPNPQFQSPPAKQTS
1 24
P130Cas (human) GPsPQFQsPPAkQTS S139-p
P130Cas iso2 (human) GPSPQFQSPPAKQTS S157
P130Cas iso6 (human) GPSPQFQSPPAKQTS S185
P130Cas iso7 (human) GPSPQFQSPPAKQTS S157
P130Cas iso8 (human) GPSPQFQSPPAKQTS S139
P130Cas (mouse) GPNPQFQsPPAKQTS S143-p
P130Cas (rat) GPNPQFQSPPAKQTS S237
P130Cas iso2 (rat) GPNPQFQsPPAKQTS S143-p
K241
QFQSPPAKQTSTFSK
0 1
P130Cas (human) QFQsPPAkQTSTFSK K143-ac
P130Cas iso2 (human) QFQSPPAKQTSTFSK K161
P130Cas iso6 (human) QFQSPPAKQTSTFSK K189
P130Cas iso7 (human) QFQSPPAKQTSTFSK K161
P130Cas iso8 (human) QFQSPPAKQTSTFSK K143
P130Cas (mouse) QFQsPPAKQTSTFSK K147
P130Cas (rat) QFQSPPAKQTSTFSK K241
P130Cas iso2 (rat) QFQsPPAKQTSTFSK K147
Y263-p
PSPATDLyQVPPGPG
Upstream
11 1
P130Cas (human)
Y165-p
P130Cas (mouse)
Y169-p
P130Cas (rat)
Y263-p
Kinase, in vitro:
  • FAK (rat)
  • Src (chicken)
Putative in vivo kinases:
  • FAK (rat)
Regulatory protein:
  • Src (human)
Treatment
  • RGD
P130Cas (human) PSPATDLyQVPPGPG Y165-p
P130Cas iso2 (human) PSPATDLYQVPPGPG Y183
P130Cas iso6 (human) PSPATDLYQVPPGPG Y211
P130Cas iso7 (human) PSPATDLYQVPPGPG Y183
P130Cas iso8 (human) PSPATDLYQVPPGPG Y165
P130Cas (mouse) PSPATDLyQVPPGPG Y169-p
P130Cas (rat) PSPATDLyQVPPGPG Y263-p
P130Cas iso2 (rat) PSPATDLyQVPPGPG Y169-p
Y277-p
GSPAQDIyQVPPSAG
Upstream
1 3
Kinase, in vitro:
  • Src (chicken)
P130Cas (human) GGPAQDIyQVPPsAG Y179-p
P130Cas iso2 (human) GGPAQDIYQVPPSAG Y197
P130Cas iso6 (human) GGPAQDIYQVPPSAG Y225
P130Cas iso7 (human) GGPAQDIYQVPPSAG Y197
P130Cas iso8 (human) GGPAQDIYQVPPSAG Y179
P130Cas (mouse) GSPAQDIYQVPPSAG Y183
P130Cas (rat) GSPAQDIyQVPPSAG Y277-p
P130Cas iso2 (rat) GSPAQDIyQVPPSAG Y183-p
S282
DIyQVPPSAGTGHDI
0 1
P130Cas (human) DIyQVPPsAGMGHDI S184-p
P130Cas iso2 (human) DIYQVPPSAGMGHDI S202
P130Cas iso6 (human) DIYQVPPSAGMGHDI S230
P130Cas iso7 (human) DIYQVPPSAGMGHDI S202
P130Cas iso8 (human) DIYQVPPSAGMGHDI S184
P130Cas (mouse) DIYQVPPSAGIGHDI S188
P130Cas (rat) DIyQVPPSAGTGHDI S282
P130Cas iso2 (rat) DIyQVPPSAGTGHDI S188
Y290-p
AGTGHDIyQVPPSLD
Upstream
1 5
Kinase, in vitro:
  • Src (chicken)
P130Cas (human) AGMGHDIyQVPPSMD Y192-p
P130Cas iso2 (human) AGMGHDIYQVPPSMD Y210
P130Cas iso6 (human) AGMGHDIYQVPPSMD Y238
P130Cas iso7 (human) AGMGHDIYQVPPSMD Y210
P130Cas iso8 (human) AGMGHDIYQVPPSMD Y192
P130Cas (mouse) AGIGHDIyQVPPSLD Y196-p
P130Cas (rat) AGTGHDIyQVPPSLD Y290-p
P130Cas iso2 (rat) AGTGHDIyQVPPSLD Y196-p
S300
PPSLDTRSWEGTKPP
0 2
P130Cas (human) PPSMDTRsWEGTKPP S202-p
P130Cas iso2 (human) PPSMDTRSWEGTKPP S220
P130Cas iso6 (human) PPSMDTRSWEGTKPP S248
P130Cas iso7 (human) PPSMDTRSWEGTKPP S220
P130Cas iso8 (human) PPSMDTRSWEGTKPP S202
P130Cas (mouse) PPSLDTRGWEGTKPP G206
P130Cas (rat) PPSLDTRSWEGTKPP S300
P130Cas iso2 (rat) PPSLDTRSWEGTKPP S206
Y320
PTRVGQGYVYEASQA
0 6
P130Cas (human) PTRVGQGyVyEAAQP Y222-p
P130Cas iso2 (human) PTRVGQGYVYEAAQP Y240
P130Cas iso6 (human) PTRVGQGYVYEAAQP Y268
P130Cas iso7 (human) PTRVGQGYVYEAAQP Y240
P130Cas iso8 (human) PTRVGQGYVYEAAQP Y222
P130Cas (mouse) PTRVGQGyVyEAAQT Y226-p
P130Cas (rat) PTRVGQGYVYEASQA Y320
P130Cas iso2 (rat) PTRVGQGYVYEASQA Y226
Y322
RVGQGYVYEASQAEQ
0 91
P130Cas (human) RVGQGyVyEAAQPEQ Y224-p
P130Cas iso2 (human) RVGQGYVYEAAQPEQ Y242
P130Cas iso6 (human) RVGQGYVYEAAQPEQ Y270
P130Cas iso7 (human) RVGQGYVYEAAQPEQ Y242
P130Cas iso8 (human) RVGQGYVYEAAQPEQ Y224
P130Cas (mouse) RVGQGyVyEAAQTEQ Y228-p
P130Cas (rat) RVGQGYVYEASQAEQ Y322
P130Cas iso2 (rat) RVGQGYVYEASQAEQ Y228
Y332-p
SQAEQDEyDTPRHLL
Upstream
2 725
Kinase, in vitro:
  • Src (chicken)
P130Cas (human) AQPEQDEyDIPRHLL Y234-p
P130Cas iso2 (human) AQPEQDEYDIPRHLL Y252
P130Cas iso6 (human) AQPEQDEYDIPRHLL Y280
P130Cas iso7 (human) AQPEQDEYDIPRHLL Y252
P130Cas iso8 (human) AQPEQDEYDIPRHLL Y234
P130Cas (mouse) AQTEQDEyDtPRHLL Y238-p
P130Cas (rat) SQAEQDEyDTPRHLL Y332-p
P130Cas iso2 (rat) SQAEQDEyDTPRHLL Y238-p
T334
AEQDEyDTPRHLLAP
0 2
P130Cas (human) PEQDEyDIPRHLLAP I236
P130Cas iso2 (human) PEQDEYDIPRHLLAP I254
P130Cas iso6 (human) PEQDEYDIPRHLLAP I282
P130Cas iso7 (human) PEQDEYDIPRHLLAP I254
P130Cas iso8 (human) PEQDEYDIPRHLLAP I236
P130Cas (mouse) TEQDEyDtPRHLLAP T240-p
P130Cas (rat) AEQDEyDTPRHLLAP T334
P130Cas iso2 (rat) AEQDEyDTPRHLLAP T240
Y347-p
APGSQDIyDVPPVRG
Upstream
Downstream
11 763
P130Cas (human)
Y249-p
P130Cas (mouse)
Y253-p
P130Cas (rat)
Y347-p
Effects on Biological Processes:
  • cell motility, altered
Kinase, in vitro:
  • Src (chicken)
Regulatory protein:
  • Src (human)
Treatment
  • RGD
P130Cas (human) APGPQDIyDVPPVRG Y249-p
P130Cas iso2 (human) APGPQDIYDVPPVRG Y267
P130Cas iso6 (human) APGPQDIYDVPPVRG Y295
P130Cas iso7 (human) APGPQDIYDVPPVRG Y267
P130Cas iso8 (human) APGPQDIYDVPPVRG Y249
P130Cas (mouse) APGPQDIyDVPPVRG Y253-p
P130Cas (rat) APGSQDIyDVPPVRG Y347-p
P130Cas iso2 (rat) APGSQDIyDVPPVRG Y253-p
N358
PVRGLLPNQYGQEVy
0 1
P130Cas (human) PVRGLLPsQyGQEVy S260-p
P130Cas iso2 (human) PVRGLLPSQYGQEVY S278
P130Cas iso6 (human) PVRGLLPSQYGQEVY S306
P130Cas iso7 (human) PVRGLLPSQYGQEVY S278
P130Cas iso8 (human) PVRGLLPSQYGQEVY S260
P130Cas (mouse) PVRGLLPNQyGQEVy N264
P130Cas (rat) PVRGLLPNQYGQEVy N358
P130Cas iso2 (rat) PVRGLLPNQYGQEVy N264
Y360
RGLLPNQYGQEVyDT
0 4
P130Cas (human) RGLLPsQyGQEVyDt Y262-p
P130Cas iso2 (human) RGLLPSQYGQEVYDT Y280
P130Cas iso6 (human) RGLLPSQYGQEVYDT Y308
P130Cas iso7 (human) RGLLPSQYGQEVYDT Y280
P130Cas iso8 (human) RGLLPSQYGQEVYDT Y262
P130Cas (mouse) RGLLPNQyGQEVyDt Y266-p
P130Cas (rat) RGLLPNQYGQEVyDT Y360
P130Cas iso2 (rat) RGLLPNQYGQEVyDT Y266
Y365-p
NQYGQEVyDTPPMAV
Upstream
2 305
Kinase, in vitro:
  • Src (chicken)
P130Cas (human) sQyGQEVyDtPPMAV Y267-p
P130Cas iso2 (human) SQYGQEVYDTPPMAV Y285
P130Cas iso6 (human) SQYGQEVYDTPPMAV Y313
P130Cas iso7 (human) SQYGQEVYDTPPMAV Y285
P130Cas iso8 (human) SQYGQEVYDTPPMAV Y267
P130Cas (mouse) NQyGQEVyDtPPMAV Y271-p
P130Cas (rat) NQYGQEVyDTPPMAV Y365-p
P130Cas iso2 (rat) NQYGQEVyDTPPMAV Y271-p
T367
YGQEVyDTPPMAVKG
0 27
P130Cas (human) yGQEVyDtPPMAVKG T269-p
P130Cas iso2 (human) YGQEVYDTPPMAVKG T287
P130Cas iso6 (human) YGQEVYDTPPMAVKG T315
P130Cas iso7 (human) YGQEVYDTPPMAVKG T287
P130Cas iso8 (human) YGQEVYDTPPMAVKG T269
P130Cas (mouse) yGQEVyDtPPMAVKG T273-p
P130Cas (rat) YGQEVyDTPPMAVKG T367
P130Cas iso2 (rat) YGQEVyDTPPMAVKG T273
Y385-p
RDPLLDVyDVPPSVE
Upstream
1 300
Kinase, in vitro:
  • Src (chicken)
P130Cas (human) RDPLLEVyDVPPsVE Y287-p
P130Cas iso2 (human) RDPLLEVYDVPPSVE Y305
P130Cas iso6 (human) RDPLLEVYDVPPSVE Y333
P130Cas iso7 (human) RDPLLEVYDVPPSVE Y305
P130Cas iso8 (human) RDPLLEVYDVPPSVE Y287
P130Cas (mouse) RDPLLDVyDVPPSVE Y291-p
P130Cas (rat) RDPLLDVyDVPPSVE Y385-p
P130Cas iso2 (rat) RDPLLDVyDVPPSVE Y291-p
S390
DVyDVPPSVEKGLPP
0 7
P130Cas (human) EVyDVPPsVEKGLPP S292-p
P130Cas iso2 (human) EVYDVPPSVEKGLPP S310
P130Cas iso6 (human) EVYDVPPSVEKGLPP S338
P130Cas iso7 (human) EVYDVPPSVEKGLPP S310
P130Cas iso8 (human) EVYDVPPSVEKGLPP S292
P130Cas (mouse) DVyDVPPSVEKGLLS S296
P130Cas (rat) DVyDVPPSVEKGLPP S390
P130Cas iso2 (rat) DVyDVPPSVEKGLPP S296
S398
VEKGLPPSNHHSVyD
0 8
P130Cas (human) VEKGLPPsNHHAVyD S300-p
P130Cas iso2 (human) VEKGLPPSNHHAVYD S318
P130Cas iso6 (human) VEKGLPPSNHHAVYD S346
P130Cas iso7 (human) VEKGLPPSNHHAVYD S318
P130Cas iso8 (human) VEKGLPPSNHHAVYD S300
P130Cas (mouse) VEKGLLSSSHHSVyD S304
P130Cas (rat) VEKGLPPSNHHSVyD S398
P130Cas iso2 (rat) VEKGLPPSNHHSVyD S304
Y404-p
PSNHHSVyDVPPSVS
Upstream
2 205
Kinase, in vitro:
  • Src (chicken)
P130Cas (human) PsNHHAVyDVPPsVs Y306-p
P130Cas iso2 (human) PSNHHAVYDVPPSVS Y324
P130Cas iso6 (human) PSNHHAVYDVPPSVS Y352
P130Cas iso7 (human) PSNHHAVYDVPPSVS Y324
P130Cas iso8 (human) PSNHHAVYDVPPSVS Y306
P130Cas (mouse) SSSHHSVyDVPPSVS Y310-p
P130Cas (rat) PSNHHSVyDVPPSVS Y404-p
P130Cas iso2 (rat) PSNHHSVyDVPPSVS Y310-p
S409
SVyDVPPSVSKDVPD
0 2
P130Cas (human) AVyDVPPsVsKDVPD S311-p
P130Cas iso2 (human) AVYDVPPSVSKDVPD S329
P130Cas iso6 (human) AVYDVPPSVSKDVPD S357
P130Cas iso7 (human) AVYDVPPSVSKDVPD S329
P130Cas iso8 (human) AVYDVPPSVSKDVPD S311
P130Cas (mouse) SVyDVPPSVSKDVPD S315
P130Cas (rat) SVyDVPPSVSKDVPD S409
P130Cas iso2 (rat) SVyDVPPSVSKDVPD S315
S411
yDVPPSVSKDVPDGP
0 1
P130Cas (human) yDVPPsVsKDVPDGP S313-p
P130Cas iso2 (human) YDVPPSVSKDVPDGP S331
P130Cas iso6 (human) YDVPPSVSKDVPDGP S359
P130Cas iso7 (human) YDVPPSVSKDVPDGP S331
P130Cas iso8 (human) YDVPPSVSKDVPDGP S313
P130Cas (mouse) yDVPPSVSKDVPDGP S317
P130Cas (rat) yDVPPSVSKDVPDGP S411
P130Cas iso2 (rat) yDVPPSVSKDVPDGP S317
T424
GPLLREETYDVPPAF
0 27
P130Cas (human) GPLLREEtyDVPPAF T326-p
P130Cas iso2 (human) GPLLREETYDVPPAF T344
P130Cas iso6 (human) GPLLREETYDVPPAF T372
P130Cas iso7 (human) GPLLREETYDVPPAF T344
P130Cas iso8 (human) GPLLREETYDVPPAF T326
P130Cas (mouse) GPLLREEtyDVPPAF T330-p
P130Cas (rat) GPLLREETYDVPPAF T424
P130Cas iso2 (rat) GPLLREETYDVPPAF T330
Y425
PLLREETYDVPPAFA
1 211
P130Cas (human) PLLREEtyDVPPAFA Y327-p
P130Cas iso2 (human) PLLREETYDVPPAFA Y345
P130Cas iso6 (human) PLLREETYDVPPAFA Y373
P130Cas iso7 (human) PLLREETYDVPPAFA Y345
P130Cas iso8 (human) PLLREETYDVPPAFA Y327
P130Cas (mouse) PLLREEtyDVPPAFA Y331-p
P130Cas (rat) PLLREETYDVPPAFA Y425
P130Cas iso2 (rat) PLLREETYDVPPAFA Y331
S453
LAAPPPDSPPAEDVY
0 3
P130Cas (human) LAAPPPDsPPAEDVy S355-p
P130Cas iso2 (human) LAAPPPDSPPAEDVY S373
P130Cas iso6 (human) LAAPPPDSPPAEDVY S401
P130Cas iso7 (human) LAAPPPDSPPAEDVY S373
P130Cas iso8 (human) LAAPPPDSPPAEDVY S355
P130Cas (mouse) LAAPPPDSPAAEDVy S359
P130Cas (rat) LAAPPPDSPPAEDVY S453
P130Cas iso2 (rat) LAAPPPDSPPAEDVY S359
Y460
SPPAEDVYDVPPPAP
1 42
P130Cas (human) sPPAEDVyDVPPPAP Y362-p
P130Cas iso2 (human) SPPAEDVYDVPPPAP Y380
P130Cas iso6 (human) SPPAEDVYDVPPPAP Y408
P130Cas iso7 (human) SPPAEDVYDVPPPAP Y380
P130Cas iso8 (human) SPPAEDVYDVPPPAP Y362
P130Cas (mouse) SPAAEDVyDVPPPAP Y366-p
P130Cas (rat) SPPAEDVYDVPPPAP Y460
P130Cas iso2 (rat) SPPAEDVYDVPPPAP Y366
Y470
PPPAPDLYDVPPGLR
0 54
P130Cas (human) PPPAPDLyDVPPGLR Y372-p
P130Cas iso2 (human) PPPAPDLYDVPPGLR Y390
P130Cas iso6 (human) PPPAPDLYDVPPGLR Y418
P130Cas iso7 (human) PPPAPDLYDVPPGLR Y390
P130Cas iso8 (human) PPPAPDLYDVPPGLR Y372
P130Cas (mouse) PPPAPDLyDVPPGLR Y376-p
P130Cas (rat) PPPAPDLYDVPPGLR Y470
P130Cas iso2 (rat) PPPAPDLYDVPPGLR Y376
T483
LRRPGPGTLyDVPRE
0 93
P130Cas (human) LRRPGPGtLyDVPRE T385-p
P130Cas iso2 (human) LRRPGPGTLYDVPRE T403
P130Cas iso6 (human) LRRPGPGTLYDVPRE T431
P130Cas iso7 (human) LRRPGPGTLYDVPRE T403
P130Cas iso8 (human) LRRPGPGTLYDVPRE T385
P130Cas (mouse) LRRPGPGtLyDVPRE T389-p
P130Cas (rat) LRRPGPGTLyDVPRE T483
P130Cas iso2 (rat) LRRPGPGTLyDVPRE T389
Y485-p
RPGPGTLyDVPRERV
Upstream
1 472
Kinase, in vitro:
  • Src (chicken)
P130Cas (human) RPGPGtLyDVPRERV Y387-p
P130Cas iso2 (human) RPGPGTLYDVPRERV Y405
P130Cas iso6 (human) RPGPGTLYDVPRERV Y433
P130Cas iso7 (human) RPGPGTLYDVPRERV Y405
P130Cas iso8 (human) RPGPGTLYDVPRERV Y387
P130Cas (mouse) RPGPGtLyDVPRERV Y391-p
P130Cas (rat) RPGPGTLyDVPRERV Y485-p
P130Cas iso2 (rat) RPGPGTLyDVPRERV Y391-p
S501
PPEVADGSVIDDGVy
0 1
P130Cas (human) PPEVADGGVVDsGVy G403
P130Cas iso2 (human) PPEVADGGVVDSGVY G421
P130Cas iso6 (human) PPEVADGGVVDSGVY G449
P130Cas iso7 (human) PPEVADGGVVDSGVY G421
P130Cas iso8 (human) PPEVADGGVVDSGVY G403
P130Cas (mouse) PPEVADGsVVDDGVy S407-p
P130Cas (rat) PPEVADGSVIDDGVy S501
P130Cas iso2 (rat) PPEVADGSVIDDGVy S407
D505
ADGSVIDDGVyAVPP
0 4
P130Cas (human) ADGGVVDsGVyAVPP S407-p
P130Cas iso2 (human) ADGGVVDSGVYAVPP S425
P130Cas iso6 (human) ADGGVVDSGVYAVPP S453
P130Cas iso7 (human) ADGGVVDSGVYAVPP S425
P130Cas iso8 (human) ADGGVVDSGVYAVPP S407
P130Cas (mouse) ADGsVVDDGVyAVPP D411
P130Cas (rat) ADGSVIDDGVyAVPP D505
P130Cas iso2 (rat) ADGSVIDDGVyAVPP D411
Y508-p
SVIDDGVyAVPPPAE
Upstream
13 147
P130Cas (human)
Y410-p
P130Cas (mouse)
Y414-p
P130Cas (rat)
Y508-p
Kinase, in vitro:
  • Src (chicken)
Putative in vivo kinases:
  • Src (rat)
Treatment
  • 5-HT
  • imatinib
  • ketanserin
  • peptide inhibitor
  • phenylephrine
  • PP1
P130Cas (human) GVVDsGVyAVPPPAE Y410-p
P130Cas iso2 (human) GVVDSGVYAVPPPAE Y428
P130Cas iso6 (human) GVVDSGVYAVPPPAE Y456
P130Cas iso7 (human) GVVDSGVYAVPPPAE Y428
P130Cas iso8 (human) GVVDSGVYAVPPPAE Y410
P130Cas (mouse) sVVDDGVyAVPPPAE Y414-p
P130Cas (rat) SVIDDGVyAVPPPAE Y508-p
P130Cas iso2 (rat) SVIDDGVyAVPPPAE Y414-p
S526
PTDGKRLSASSTGST
0 15
P130Cas (human) PAEGKRLsAsstGst S428-p
P130Cas iso2 (human) PAEGKRLSASSTGST S446
P130Cas iso6 (human) PAEGKRLSASSTGST S474
P130Cas iso7 (human) PAEGKRLSASSTGST S446
P130Cas iso8 (human) PAEGKRLSASSTGST S428
P130Cas (mouse) PTDGKRLsASSTGST S432-p
P130Cas (rat) PTDGKRLSASSTGST S526
P130Cas iso2 (rat) PTDGKRLSASSTGST S432
S528
DGKRLSASSTGSTRS
0 1
P130Cas (human) EGKRLsAsstGstRs S430-p
P130Cas iso2 (human) EGKRLSASSTGSTRS S448
P130Cas iso6 (human) EGKRLSASSTGSTRS S476
P130Cas iso7 (human) EGKRLSASSTGSTRS S448
P130Cas iso8 (human) EGKRLSASSTGSTRS S430
P130Cas (mouse) DGKRLsASSTGSTRS S434
P130Cas (rat) DGKRLSASSTGSTRS S528
P130Cas iso2 (rat) DGKRLSASSTGSTRs S434
S529
GKRLSASSTGSTRSS
0 1
P130Cas (human) GKRLsAsstGstRss S431-p
P130Cas iso2 (human) GKRLSASSTGSTRSS S449
P130Cas iso6 (human) GKRLSASSTGSTRSS S477
P130Cas iso7 (human) GKRLSASSTGSTRSS S449
P130Cas iso8 (human) GKRLSASSTGSTRSS S431
P130Cas (mouse) GKRLsASSTGSTRSS S435
P130Cas (rat) GKRLSASSTGSTRSS S529
P130Cas iso2 (rat) GKRLSASSTGSTRsS S435
T530
KRLSASSTGSTRSSQ
0 1
P130Cas (human) KRLsAsstGstRssQ T432-p
P130Cas iso2 (human) KRLSASSTGSTRSSQ T450
P130Cas iso6 (human) KRLSASSTGSTRSSQ T478
P130Cas iso7 (human) KRLSASSTGSTRSSQ T450
P130Cas iso8 (human) KRLSASSTGSTRSSQ T432
P130Cas (mouse) KRLsASSTGSTRSSQ T436
P130Cas (rat) KRLSASSTGSTRSSQ T530
P130Cas iso2 (rat) KRLSASSTGSTRsSQ T436
S532
LSASSTGSTRSSQSA
0 2
P130Cas (human) LsAsstGstRssQsA S434-p
P130Cas iso2 (human) LSASSTGSTRSSQSA S452
P130Cas iso6 (human) LSASSTGSTRSSQSA S480
P130Cas iso7 (human) LSASSTGSTRSSQSA S452
P130Cas iso8 (human) LSASSTGSTRSSQSA S434
P130Cas (mouse) LsASSTGSTRSSQSA S438
P130Cas (rat) LSASSTGSTRSSQSA S532
P130Cas iso2 (rat) LSASSTGSTRsSQSA S438
T533
SASSTGSTRSSQSAS
0 1
P130Cas (human) sAsstGstRssQsAS T435-p
P130Cas iso2 (human) SASSTGSTRSSQSAS T453
P130Cas iso6 (human) SASSTGSTRSSQSAS T481
P130Cas iso7 (human) SASSTGSTRSSQSAS T453
P130Cas iso8 (human) SASSTGSTRSSQSAS T435
P130Cas (mouse) sASSTGSTRSSQSAS T439
P130Cas (rat) SASSTGSTRSSQSAS T533
P130Cas iso2 (rat) SASSTGSTRsSQSAS T439
S535
SSTGSTRSSQSASSL
1 1
P130Cas (human) sstGstRssQsASSL S437-p
P130Cas iso2 (human) SSTGSTRSSQSASSL S455
P130Cas iso6 (human) SSTGSTRSSQSASSL S483
P130Cas iso7 (human) SSTGSTRSSQSASSL S455
P130Cas iso8 (human) SSTGSTRSSQSASSL S437
P130Cas (mouse) SSTGSTRSSQSASSL S441
P130Cas (rat) SSTGSTRSSQSASSL S535
P130Cas iso2 (rat) SSTGSTRsSQSASSL S441-p
S536
STGSTRSSQSASSLE
0 1
P130Cas (human) stGstRssQsASSLE S438-p
P130Cas iso2 (human) STGSTRSSQSASSLE S456
P130Cas iso6 (human) STGSTRSSQSASSLE S484
P130Cas iso7 (human) STGSTRSSQSASSLE S456
P130Cas iso8 (human) STGSTRSSQSASSLE S438
P130Cas (mouse) STGSTRSSQSASSLE S442
P130Cas (rat) STGSTRSSQSASSLE S536
P130Cas iso2 (rat) STGSTRsSQSASSLE S442
S538
GSTRSSQSASSLEVV
0 1
P130Cas (human) GstRssQsASSLEVA S440-p
P130Cas iso2 (human) GSTRSSQSASSLEVA S458
P130Cas iso6 (human) GSTRSSQSASSLEVA S486
P130Cas iso7 (human) GSTRSSQSASSLEVA S458
P130Cas iso8 (human) GSTRSSQSASSLEVA S440
P130Cas (mouse) GSTRSSQSASSLEVV S444
P130Cas (rat) GSTRSSQSASSLEVV S538
P130Cas iso2 (rat) GSTRsSQSASSLEVV S444
T634
ATHTSDRTLHAKLSR
0 1
P130Cas (human) AAHTSDRALHAKLSR A536
P130Cas iso2 (human) AAHTSDRALHAKLSR A554
P130Cas iso6 (human) AAHTSDRALHAKLSR A582
P130Cas iso7 (human) AAHTSDRALHAKLSR A554
P130Cas iso8 (human) AAHTSDRALHAKLSR A536
P130Cas (mouse) ATHTSDRtLHAKLSR T540-p
P130Cas (rat) ATHTSDRTLHAKLSR T634
P130Cas iso2 (rat) ATHTSDRTLHAKLSR T540
Y650-p
LQKMEDVyQTLVVHG
0 9
P130Cas (human) LQKMEDVHQTLVAHG H552
P130Cas iso2 (human) LQKMEDVHQTLVAHG H570
P130Cas iso6 (human) LQKMEDVHQTLVAHG H598
P130Cas iso7 (human) LQKMEDVHQTLVAHG H570
P130Cas iso8 (human) LQKMEDVHQTLVAHG H552
P130Cas (mouse) LQKMEDVyQtLVVHG Y556-p
P130Cas (rat) LQKMEDVyQTLVVHG Y650-p
P130Cas iso2 (rat) LQKMEDVYQTLVVHG Y556
T652
KMEDVyQTLVVHGQV
0 2
P130Cas (human) KMEDVHQTLVAHGQA T554
P130Cas iso2 (human) KMEDVHQTLVAHGQA T572
P130Cas iso6 (human) KMEDVHQTLVAHGQA T600
P130Cas iso7 (human) KMEDVHQTLVAHGQA T572
P130Cas iso8 (human) KMEDVHQTLVAHGQA T554
P130Cas (mouse) KMEDVyQtLVVHGQV T558-p
P130Cas (rat) KMEDVyQTLVVHGQV T652
P130Cas iso2 (rat) KMEDVYQTLVVHGQV T558
G666
VLDSGRGGPGFTLDD
0 1
P130Cas (human) ALDAGRGGSGATLED G568
P130Cas iso2 (human) ALDAGRGGSGATLED G586
P130Cas iso6 (human) ALDAGRGGSGATLED G614
P130Cas iso7 (human) ALDAGRGGSGATLED G586
P130Cas iso8 (human) ALDAGRGGSGATLED G568
P130Cas (mouse) VLDSGRGsPGFTPED S572-p
P130Cas (rat) VLDSGRGGPGFTLDD G666
P130Cas iso2 (rat) VLDSGRGGPGFTLDD G572
S700
SFLHGNASLLFRRTK
0 1
P130Cas (human) SFLHGNAsLLFRRTK S602-p
P130Cas iso2 (human) SFLHGNASLLFRRTK S620
P130Cas iso6 (human) SFLHGNASLLFRRTK S648
P130Cas iso7 (human) SFLHGNASLLFRRTK S620
P130Cas iso8 (human) SFLHGNASLLFRRTK S602
P130Cas (mouse) SFLHGNASLLFRRTK S606
P130Cas (rat) SFLHGNASLLFRRTK S700
P130Cas iso2 (rat) SFLHGNASLLFRRTK S606
S737-p
IQSRPLPsPPKFTSQ
Upstream
2 15
Regulatory protein:
  • Src (human)
P130Cas (human) IQSRPLPsPPKFTSQ S639-p
P130Cas iso2 (human) IQSRPLPSPPKFTSQ S657
P130Cas iso6 (human) IQSRPLPSPPKFTSQ S685
P130Cas iso7 (human) IQSRPLPSPPKFTSQ S657
P130Cas iso8 (human) IQSRPLPSPPKFTSQ S639
P130Cas (mouse) IQSRPLPsPPKFTSQ S643-p
P130Cas (rat) IQSRPLPsPPKFTSQ S737-p
P130Cas iso2 (rat) IQSRPLPsPPKFTSQ S643-p
S746
PKFTSQDSPDGQyEN
0 1
P130Cas (human) PKFTSQDsPDGQyEN S648-p
P130Cas iso2 (human) PKFTSQDSPDGQYEN S666
P130Cas iso6 (human) PKFTSQDSPDGQYEN S694
P130Cas iso7 (human) PKFTSQDSPDGQYEN S666
P130Cas iso8 (human) PKFTSQDSPDGQYEN S648
P130Cas (mouse) PKFTSQDSPDGQYEN S652
P130Cas (rat) PKFTSQDSPDGQyEN S746
P130Cas iso2 (rat) PKFTSQDSPDGQYEN S652
Y751-p
QDSPDGQyENSEGGW
1 1
P130Cas (human) QDsPDGQyENSEGGW Y653-p
P130Cas iso2 (human) QDSPDGQYENSEGGW Y671
P130Cas iso6 (human) QDSPDGQYENSEGGW Y699
P130Cas iso7 (human) QDSPDGQYENSEGGW Y671
P130Cas iso8 (human) QDSPDGQYENSEGGW Y653
P130Cas (mouse) QDSPDGQYENSEGGW Y657
P130Cas (rat) QDSPDGQyENSEGGW Y751-p
P130Cas iso2 (rat) QDSPDGQYENSEGGW Y657
Y762-p
EGGWMEDyDyVHLQG
Upstream
Downstream
6 26
Effects on Modified Protein
  • molecular association, regulation
  • phosphorylation
Kinase, in vitro:
  • FAK (rat)
Putative in vivo kinases:
  • FAK (rat)
P130Cas (human) EGGWMEDyDyVHLQG Y664-p
P130Cas iso2 (human) EGGWMEDYDYVHLQG Y682
P130Cas iso6 (human) EGGWMEDYDYVHLQG Y710
P130Cas iso7 (human) EGGWMEDYDYVHLQG Y682
P130Cas iso8 (human) EGGWMEDYDYVHLQG Y664
P130Cas (mouse) EGGWMEDyDyVHLQG Y668-p
P130Cas (rat) EGGWMEDyDyVHLQG Y762-p
P130Cas iso2 (rat) EGGWMEDYDYVHLQG Y668
Y764-p
GWMEDyDyVHLQGKE
Upstream
Downstream
2 26
Effects on Modified Protein
  • molecular association, regulation
Kinase, in vitro:
  • FAK (rat)
Putative in vivo kinases:
  • FAK (rat)
P130Cas (human) GWMEDyDyVHLQGKE Y666-p
P130Cas iso2 (human) GWMEDYDYVHLQGKE Y684
P130Cas iso6 (human) GWMEDYDYVHLQGKE Y712
P130Cas iso7 (human) GWMEDYDYVHLQGKE Y684
P130Cas iso8 (human) GWMEDYDYVHLQGKE Y666
P130Cas (mouse) GWMEDyDyVHLQGKE Y670-p
P130Cas (rat) GWMEDyDyVHLQGKE Y764-p
P130Cas iso2 (rat) GWMEDYDYVHLQGKE Y670
K791
GNIVRQGKGQLELQQ
0 2