Other Species / Isoforms
  LRRK1 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

  HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
T30
CPERAMEtLNGAGDT
0 1
LRRK1 (human) CPERAMEtLNGAGDT T30
LRRK1 (mouse) CPGPAMETHNGAEDM T30
T175
VVKLLVLtHGADPEs
0 1
LRRK1 (human) VVKLLVLtHGADPEs T175
LRRK1 (mouse) VVKLLVLTHGADPEN T175
S182
tHGADPEsyAVRKNE
0 1
LRRK1 (human) tHGADPEsyAVRKNE S182
LRRK1 (mouse) THGADPENYAVRKNE N182
Y183
HGADPEsyAVRKNEF
0 1
LRRK1 (human) HGADPEsyAVRKNEF Y183
LRRK1 (mouse) HGADPENYAVRKNEF Y183
S249
EASPLPSsYPGKTAL
0 1
LRRK1 (human) EASPLPSsYPGKTAL S249
LRRK1 (mouse) EASALPSSYPGKIAL S249
S337
RLLEIDIsSNKLSHL
0 1
LRRK1 (human) RLLEIDIsSNKLSHL S337
LRRK1 (mouse) RLLEIDISSNKLsHL S337
S342
DIsSNKLSHLPPGFL
0 1
LRRK1 (human) DIsSNKLSHLPPGFL S342
LRRK1 (mouse) DISSNKLsHLPPGFL S342
S352
PPGFLHLSKLQKLtA
0 1
LRRK1 (human) PPGFLHLSKLQKLtA S352
LRRK1 (mouse) PPGFLHLsKLQKLTA S352
T358
LSKLQKLtAsKNCLE
0 13
LRRK1 (human) LSKLQKLtAsKNCLE T358
LRRK1 (mouse) LsKLQKLTAsKNYLE T358
S360
KLQKLtAsKNCLEKL
0 13
LRRK1 (human) KLQKLtAsKNCLEKL S360
LRRK1 (mouse) KLQKLTAsKNYLERL S360
S405
LFLHSFKsLNSLNVS
0 1
LRRK1 (human) LFLHSFKsLNSLNVS S405
LRRK1 (mouse) QFMHSFKSLTSLNVS S405
T823
RQLIFHVTCSMKDVG
0 1
LRRK1 (human) RQLIFHVTCSMKDVG T823
LRRK1 (mouse) RQLIFHVtCNMKDVG T823
Y971
TQQTEEQyFQFLAKF
Upstream
Downstream
2 0
Effects on Modified Protein
  • enzymatic activity, inhibited
  • intracellular localization
Effects on Biological Processes:
  • endocytosis, altered
Kinase, in vitro:
  • EGFR (human)
Phosphatases, in vitro:
  • PTP1B (human)
Putative in vivo kinases:
  • EGFR (human)
Putative upstream phosphatases:
  • PTP1B (human)
Treatment
  • EGF
  • siRNA
  • vanadate
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LRRK1 (human) TQQTEEQyFQFLAKF Y971
LRRK1 (mouse) TQQTEEQYFQFLAKF Y971
S1038
FIARMLISLAEMDLQ
0 1
LRRK1 (human) FIARMLISLAEMDLQ S1038
LRRK1 (mouse) FIARMLIsLAEMDLQ S1038
Y1063
RNRKVTIysFTGNQR
0 7
LRRK1 (human) RNRKVTIysFTGNQR Y1063
LRRK1 (mouse) RNRKVTIySFTGSQR Y1063
S1064
NRKVTIysFTGNQRN
Upstream
Downstream
1 2
Effects on Modified Protein
  • enzymatic activity, induced
  • phosphorylation
Putative in vivo kinases:
  • PKCA (human)
Treatment
  • Go_6983
  • LXS-196
  • phorbol_ester
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LRRK1 (human) NRKVTIysFTGNQRN S1064
LRRK1 (mouse) NRKVTIySFTGSQRN S1064
S1074
GNQRNRCstFRVKRN
Upstream
Downstream
1 1
Effects on Modified Protein
  • enzymatic activity, induced
  • phosphorylation
Putative in vivo kinases:
  • PKCA (human)
Treatment
  • Go_6983
  • LXS-196
  • phorbol_ester
view more >
LRRK1 (human) GNQRNRCstFRVKRN S1074
LRRK1 (mouse) GSQRNRCSTFRVRRN S1074
T1075
NQRNRCstFRVKRNQ
Upstream
Downstream
1 1
Effects on Modified Protein
  • enzymatic activity, induced
  • phosphorylation
Putative in vivo kinases:
  • PKCA (human)
Treatment
  • Go_6983
  • LXS-196
  • phorbol_ester
view more >
LRRK1 (human) NQRNRCstFRVKRNQ T1075
LRRK1 (mouse) SQRNRCSTFRVRRNQ T1075
Y1098
LVTFDGGyLsVEssD
0 1
LRRK1 (human) LVTFDGGyLsVEssD Y1098
LRRK1 (mouse) LVTFDGGYLSVESSD Y1098
S1100
TFDGGyLsVEssDVN
0 1
LRRK1 (human) TFDGGyLsVEssDVN S1100
LRRK1 (mouse) TFDGGYLSVESSDVN S1100
S1103
GGyLsVEssDVNWKK
0 1
LRRK1 (human) GGyLsVEssDVNWKK S1103
LRRK1 (mouse) GGYLSVESSDVNWKK S1103
S1104
GyLsVEssDVNWKKK
0 1
LRRK1 (human) GyLsVEssDVNWKKK S1104
LRRK1 (mouse) GYLSVESSDVNWKKK S1104
S1241
ENSKLEHsEDEGsVL
0 1
LRRK1 (human) ENSKLEHsEDEGsVL S1241
LRRK1 (mouse) ENSKLEHTEGENSIL T1241
S1246
EHsEDEGsVLGQGGS
0 1
LRRK1 (human) EHsEDEGsVLGQGGS S1246
LRRK1 (mouse) EHTEGENSILGQGGS S1246
Y1258
GGSGTVIYRARYQGQ
0 6
LRRK1 (human) GGSGTVIYRARYQGQ Y1258
LRRK1 (mouse) GGSGTVIyQARYQGQ Y1258
T1295
MLRHLRAtDAMKNFs
0 1
LRRK1 (human) MLRHLRAtDAMKNFs T1295
LRRK1 (mouse) MLRHLRAMDAMKNFS M1295
S1302
tDAMKNFsEFRQEAS
0 1
LRRK1 (human) tDAMKNFsEFRQEAS S1302
LRRK1 (mouse) MDAMKNFSDFRQEAS S1302
Y1368
MLTQKIAYQIASGLA
0 1
LRRK1 (human) MLTQKIAYQIASGLA Y1368
LRRK1 (mouse) MLTQKIAyQIASGLA Y1368
Y1376
QIASGLAYLHKKNII
0 1
LRRK1 (human) QIASGLAYLHKKNII Y1376
LRRK1 (mouse) QIASGLAyLHKKNII Y1376
T1427
GALGVEGtPGyQAPE
Upstream
Downstream
2 0
Effects on Modified Protein
  • enzymatic activity, induced
  • molecular association, regulation
  • phosphorylation
Effects on Biological Processes:
  • cytoskeletal reorganization
Kinase, in vitro:
  • CDK1 (human)
Treatment
  • serum
LRRK1 (human) GALGVEGtPGyQAPE T1427
LRRK1 (mouse) GALGVEGTPGyQAPE T1427
Y1430
GVEGtPGyQAPEIRP
0 9
LRRK1 (human) GVEGtPGyQAPEIRP Y1430
LRRK1 (mouse) GVEGTPGyQAPEIRP Y1430
T1628
LDTPAVVtCFLAVPV
0 1
LRRK1 (human) LDTPAVVtCFLAVPV T1628
LRRK1 (mouse) LDTPAVVTCFLAVPV T1628
S1817
GDSIADVsIMYSEEL
Upstream
Downstream
2 0
Effects on Modified Protein
  • enzymatic activity, induced
  • molecular association, regulation
Effects on Biological Processes:
  • cytoskeletal reorganization
Kinase, in vitro:
  • PLK1 (human)
Putative in vivo kinases:
  • PLK1 (human)
Treatment
  • BI2536
  • serum
LRRK1 (human) GDSIADVsIMYSEEL S1817
LRRK1 (mouse) EECIADVSIMYSEEL S1816
S1855
PPRQAARsPSsLPSS
0 1
LRRK1 (human) PPRQAARsPSsLPSS S1855
LRRK1 (mouse) PPHQDPRSPSSLPSS S1854
S1858
QAARsPSsLPSSPAS
0 1
LRRK1 (human) QAARsPSsLPSSPAS S1858
LRRK1 (mouse) QDPRSPSSLPSSLTS S1857