Other Species / Isoforms
  HNF4 alpha (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

  HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
Y23-p
SAALDPAyTTLEFEN
Upstream
1 1
Kinase, in vitro:
  • Src (human)
Putative in vivo kinases:
  • Src (human)
HNF4 alpha (human) SAALDPAyTTLEFEN Y23-p
HNF4 alpha (mouse) SAALDPAYTTLEFEN Y23
HNF4 alpha (rat) SAALDPAYTTLEFEN Y23
S87
CKGFFRRSVRKNHMY
1 0
HNF4 alpha (human) CKGFFRRSVRKNHMY S87
HNF4 alpha (mouse) CKGFFRRSVRKNHMY S87
HNF4 alpha (rat) CKGFFRRsVRKNHMY S87-p
S95-p
VRKNHMYsCRFsRQC
Upstream
0 1
Kinase, in vitro:
  • ERK1 (human)
HNF4 alpha (human) VRKNHMYsCRFsRQC S95-p
HNF4 alpha (mouse) VRKNHMYSCRFSRQC S95
HNF4 alpha (rat) VRKNHMYSCRFSRQC S95
S99-p
HMYsCRFsRQCVVDk
0 1
HNF4 alpha (human) HMYsCRFsRQCVVDk S99-p
HNF4 alpha (mouse) HMYSCRFSRQCVVDK S99
HNF4 alpha (rat) HMYSCRFSRQCVVDK S99
K106-ac
sRQCVVDkDkRNQCR
Downstream
1 1
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
  • protein conformation
Effects on Biological Processes:
  • transcription, induced
HNF4 alpha (human) sRQCVVDkDkRNQCR K106-ac
HNF4 alpha (mouse) SRQCVVDKDKRNQCR K106
HNF4 alpha (rat) SRQCVVDKDKRNQCR K106
K108-ac
QCVVDkDkRNQCRYC
Downstream
1 0
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
  • protein conformation
Effects on Biological Processes:
  • transcription, induced
HNF4 alpha (human) QCVVDkDkRNQCRYC K108-ac
HNF4 alpha (mouse) QCVVDKDKRNQCRYC K108
HNF4 alpha (rat) QCVVDKDKRNQCRYC K108
K126-ac
KCFRAGMkkEAVQNE
Downstream
1 0
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
  • protein conformation
Effects on Biological Processes:
  • transcription, induced
HNF4 alpha (human) KCFRAGMkkEAVQNE K126-ac
HNF4 alpha (mouse) KCFRAGMKKEAVQNE K126
HNF4 alpha (rat) KCFRAGMKKEAVQNE K126
K127-ac
CFRAGMkkEAVQNER
Downstream
1 0
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
  • protein conformation
Effects on Biological Processes:
  • transcription, induced
HNF4 alpha (human) CFRAGMkkEAVQNER K127-ac
HNF4 alpha (mouse) CFRAGMKKEAVQNER K127
HNF4 alpha (rat) CFRAGMKKEAVQNER K127
S138-p
QNERDRIstRRssyE
Upstream
1 2
Kinase, in vitro:
  • ERK1 (human)
Regulatory protein:
  • PKACA (human)
Treatment
  • cytokines
HNF4 alpha (human) QNERDRIstRRssyE S138-p
HNF4 alpha (mouse) QNERDRIStRRssYE S138
HNF4 alpha (rat) QNERDRISTRRssYE S138
T139-p
NERDRIstRRssyED
Upstream
0 3
Kinase, in vitro:
  • ERK1 (human)
HNF4 alpha (human) NERDRIstRRssyED T139-p
HNF4 alpha (mouse) NERDRIStRRssYED T139-p
HNF4 alpha (rat) NERDRISTRRssYED T139
S142-p
DRIstRRssyEDssL
Upstream
Downstream
3 10
Effects on Modified Protein
  • molecular association, regulation
Effects on Biological Processes:
  • signaling pathway regulation
  • transcription, inhibited
Kinase, in vitro:
  • ERK1 (human)
Regulatory protein:
  • PKACA (human)
Treatment
  • cytokines
  • H2O2
  • IL-1b
view more >
HNF4 alpha (human) DRIstRRssyEDssL S142-p
HNF4 alpha (mouse) DRIStRRssYEDSsL S142-p
HNF4 alpha (rat) DRISTRRssYEDSSL S142-p
S143-p
RIstRRssyEDssLP
Upstream
Downstream
3 15
Effects on Modified Protein
  • molecular association, regulation
Effects on Biological Processes:
  • signaling pathway regulation
  • transcription, inhibited
Kinase, in vitro:
  • ERK1 (human)
Regulatory protein:
  • PKACA (human)
Treatment
  • cytokines
  • H2O2
  • IL-1b
view more >
HNF4 alpha (human) RIstRRssyEDssLP S143-p
HNF4 alpha (mouse) RIStRRssYEDSsLP S143-p
HNF4 alpha (rat) RISTRRssYEDSSLP S143-p
Y144-p
IstRRssyEDssLPs
0 1
HNF4 alpha (human) IstRRssyEDssLPs Y144-p
HNF4 alpha (mouse) IStRRssYEDSsLPS Y144
HNF4 alpha (rat) ISTRRssYEDSSLPS Y144
S147-p
RRssyEDssLPsINA
Upstream
1 2
Kinase, in vitro:
  • ERK1 (human)
Regulatory protein:
  • PKACA (human)
Treatment
  • cytokines
HNF4 alpha (human) RRssyEDssLPsINA S147-p
HNF4 alpha (mouse) RRssYEDSsLPSINA S147
HNF4 alpha (rat) RRssYEDSSLPSINA S147
S148-p
RssyEDssLPsINAL
Upstream
0 2
Kinase, in vitro:
  • ERK1 (human)
HNF4 alpha (human) RssyEDssLPsINAL S148-p
HNF4 alpha (mouse) RssYEDSsLPSINAL S148-p
HNF4 alpha (rat) RssYEDSSLPSINAL S148
S151-p
yEDssLPsINALLQA
Upstream
1 3
Kinase, in vitro:
  • ERK1 (human)
Regulatory protein:
  • PKACA (human)
Treatment
  • cytokines
HNF4 alpha (human) yEDssLPsINALLQA S151-p
HNF4 alpha (mouse) YEDSsLPSINALLQA S151
HNF4 alpha (rat) YEDSSLPSINALLQA S151
T166-p
EVLSRQItsPVsGIN
Upstream
2 3
Kinase, in vitro:
  • ERK1 (human)
HNF4 alpha (human) EVLSRQItsPVsGIN T166-p
HNF4 alpha (mouse) EVLSQQITsPISGIN T166
HNF4 alpha (rat) EVLSQQITSPISGIN T166
S167-p
VLSRQItsPVsGING
Upstream
Downstream
4 33
Effects on Modified Protein
  • molecular association, regulation
Effects on Biological Processes:
  • transcription, induced
Kinase, in vitro:
  • ERK1 (human)
  • P38A (human)
Putative in vivo kinases:
  • P38A (human)
  • P38B (human)
Treatment
  • H2O2
  • IL-1b
HNF4 alpha (human) VLSRQItsPVsGING S167-p
HNF4 alpha (mouse) VLSQQITsPISGING S167-p
HNF4 alpha (rat) VLSQQITSPISGING S167
S170-p
RQItsPVsGINGDIR
0 1
HNF4 alpha (human) RQItsPVsGINGDIR S170-p
HNF4 alpha (mouse) QQITsPISGINGDIR S170
HNF4 alpha (rat) QQITSPISGINGDIR S170
K180
NGDIRAKKIASIADV
0 1
HNF4 alpha (human) NGDIRAKKIASIADV K180
HNF4 alpha (mouse) NGDIRAKkIANITDV K180-ub
HNF4 alpha (rat) NGDIRAKKIANITDV K180
S190-p
SIADVCEsMKEQLLV
Upstream
2 1
Treatment
  • H2O2
  • IL-1b
HNF4 alpha (human) SIADVCEsMKEQLLV S190-p
HNF4 alpha (mouse) NITDVCEsMKEQLLV S190-p
HNF4 alpha (rat) NITDVCESMKEQLLV S190
K234-ub
HLLLGATkRSMVFKD
1 2
HNF4 alpha (human) HLLLGATkRSMVFKD K234-ub
HNF4 alpha (mouse) HLLLGATkRSMVFKD K234-ub
HNF4 alpha (rat) HLLLGATKRSMVFKD K234
S262-p
CPELAEMsRVsIRIL
Upstream
1 1
Kinase, in vitro:
  • ERK1 (human)
HNF4 alpha (human) CPELAEMsRVsIRIL S262-p
HNF4 alpha (mouse) CPELAEMsRVsIRIL S262-p
HNF4 alpha (rat) CPELAEMSRVSIRIL S262
S265-p
LAEMsRVsIRILDEL
Upstream
1 1
Kinase, in vitro:
  • ERK1 (human)
HNF4 alpha (human) LAEMsRVsIRILDEL S265-p
HNF4 alpha (mouse) LAEMsRVsIRILDEL S265-p
HNF4 alpha (rat) LAEMSRVSIRILDEL S265
Y286-p
LQIDDNEyAyLKAII
Upstream
Downstream
2 1
Effects on Modified Protein
  • intracellular localization
  • phosphorylation
  • protein degradation
Effects on Biological Processes:
  • transcription, inhibited
Kinase, in vitro:
  • Src (human)
Putative in vivo kinases:
  • Src (human)
HNF4 alpha (human) LQIDDNEyAyLKAII Y286-p
HNF4 alpha (mouse) LQIDDNEyACLKAII Y286-p
HNF4 alpha (rat) LQIDDNEYACLKAII Y286
Y288-p
IDDNEyAyLKAIIFF
Upstream
Downstream
1 1
Effects on Modified Protein
  • intracellular localization
  • phosphorylation
  • protein degradation
Effects on Biological Processes:
  • transcription, inhibited
Kinase, in vitro:
  • Src (human)
Putative in vivo kinases:
  • Src (human)
HNF4 alpha (human) IDDNEyAyLKAIIFF Y288-p
HNF4 alpha (mouse) IDDNEyACLKAIIFF C288
HNF4 alpha (rat) IDDNEYACLKAIIFF C288
K300
IFFDPDAKGLsDPGk
0 1
HNF4 alpha (human) IFFDPDAKGLsDPGk K300
HNF4 alpha (mouse) IFFDPDAkGLsDPGk K300-ub
HNF4 alpha (rat) IFFDPDAKGLSDPGK K300
S303-p
DPDAKGLsDPGkIkR
Upstream
2 1
Regulatory protein:
  • PKACA (human)
Treatment
  • cytokines
HNF4 alpha (human) DPDAKGLsDPGkIkR S303-p
HNF4 alpha (mouse) DPDAkGLsDPGkIkR S303-p
HNF4 alpha (rat) DPDAKGLSDPGKIKR S303
K307-ub
KGLsDPGkIkRLRsQ
2 3
HNF4 alpha (human) KGLsDPGkIkRLRsQ K307-ub
HNF4 alpha (mouse) kGLsDPGkIkRLRsQ K307-ub
HNF4 alpha (rat) KGLSDPGKIKRLRSQ K307
K309-ub
LsDPGkIkRLRsQVQ
1 2
HNF4 alpha (human) LsDPGkIkRLRsQVQ K309-ub
HNF4 alpha (mouse) LsDPGkIkRLRsQVQ K309-ub
HNF4 alpha (rat) LSDPGKIKRLRSQVQ K309
S313-p
GkIkRLRsQVQVsLE
Upstream
Downstream
5 3
Effects on Modified Protein
  • protein degradation
Effects on Biological Processes:
  • transcription, inhibited
Kinase, in vitro:
  • AMPKA1 (rat)
  • ERK1 (human)
Putative in vivo kinases:
  • AMPKA1 (human)
Regulatory protein:
  • PKACA (human)
Treatment
  • acadesine
  • cytokines
  • H2O2
  • IL-1b
view more >
HNF4 alpha (human) GkIkRLRsQVQVsLE S313-p
HNF4 alpha (mouse) GkIkRLRsQVQVsLE S313-p
HNF4 alpha (rat) GKIKRLRSQVQVSLE S313
S318-p
LRsQVQVsLEDYIND
Upstream
2 1
Regulatory protein:
  • PKACA (human)
Treatment
  • cytokines
HNF4 alpha (human) LRsQVQVsLEDYIND S318-p
HNF4 alpha (mouse) LRsQVQVsLEDYIND S318-p
HNF4 alpha (rat) LRSQVQVSLEDYIND S318
S378-p
QEMLLGGsPSDAPHA
Upstream
1 1
Regulatory protein:
  • PKACA (human)
Treatment
  • cytokines
HNF4 alpha (human) QEMLLGGsPSDAPHA S378-p
HNF4 alpha (mouse) QEMLLGGSASDAPHT S378
HNF4 alpha (rat) QEMLLGGSASDAPHA S378
T429-p
RPRGQAAtPEtPQPs
0 5
HNF4 alpha (human) RPRGQAAtPEtPQPs T429-p
HNF4 alpha (mouse) RPRGQAAtPEtPQPs T429-p
HNF4 alpha (rat) RPRGQAATPEtPQPs T429
T432-p
GQAAtPEtPQPsPPG
1 7
HNF4 alpha (human) GQAAtPEtPQPsPPG T432-p
HNF4 alpha (mouse) GQAAtPEtPQPsPPS T432-p
HNF4 alpha (rat) GQAATPEtPQPsPPS T432-p
S436-p
tPEtPQPsPPGGsGs
Upstream
2 9
Regulatory protein:
  • PKACA (human)
Treatment
  • cytokines
HNF4 alpha (human) tPEtPQPsPPGGsGs S436-p
HNF4 alpha (mouse) tPEtPQPsPPSGSGS S436-p
HNF4 alpha (rat) TPEtPQPsPPSGSGS S436-p
S441-p
QPsPPGGsGsEPYKL
0 1
HNF4 alpha (human) QPsPPGGsGsEPYKL S441-p
HNF4 alpha (mouse) QPsPPSGSGSESYKL S441
HNF4 alpha (rat) QPsPPSGSGSESYKL S441
S443-p
sPPGGsGsEPYKLLP
Upstream
1 1
Regulatory protein:
  • PKACA (human)
Treatment
  • cytokines
HNF4 alpha (human) sPPGGsGsEPYKLLP S443-p
HNF4 alpha (mouse) sPPSGSGSESYKLLP S443
HNF4 alpha (rat) sPPSGSGSESYKLLP S443
T455-p
LLPGAVAtIVkPLsA
Upstream
1 1
Regulatory protein:
  • PKACA (human)
Treatment
  • cytokines
HNF4 alpha (human) LLPGAVAtIVkPLsA T455-p
HNF4 alpha (mouse) LLPGAITTIVkPPSA T455
HNF4 alpha (rat) LLPGAITTIVkPPSA T455
K458-ac
GAVAtIVkPLsAIPQ
Downstream
2 2
Effects on Modified Protein
  • protein degradation
Effects on Biological Processes:
  • transcription, inhibited
HNF4 alpha (human) GAVAtIVkPLsAIPQ K458-ac
HNF4 alpha (mouse) GAITTIVkPPSAIPQ K458-ac
HNF4 alpha (rat) GAITTIVkPPSAIPQ K458-ac
S461-p
AtIVkPLsAIPQPtI
Upstream
1 1
Kinase, in vitro:
  • ERK1 (human)
HNF4 alpha (human) AtIVkPLsAIPQPtI S461-p
HNF4 alpha (mouse) TTIVkPPSAIPQPTI S461
HNF4 alpha (rat) TTIVkPPSAIPQPTI S461
T467-p
LsAIPQPtItKQEVI
Upstream
1 1
Kinase, in vitro:
  • ERK1 (human)
HNF4 alpha (human) LsAIPQPtItKQEVI T467-p
HNF4 alpha (mouse) PSAIPQPTITKQEAI T467
HNF4 alpha (rat) PSAIPQPTITKQEAI T467
T469-p
AIPQPtItKQEVI__
Upstream
2 1
Kinase, in vitro:
  • ERK1 (human)
HNF4 alpha (human) AIPQPtItKQEVI__ T469-p
HNF4 alpha (mouse) AIPQPTITKQEAI__ T469
HNF4 alpha (rat) AIPQPTITKQEAI__ T469