Other Species / Isoforms
  AQP2 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
K228-ub
YVLFPPAkSLSERLA
1 0
AQP2 (human) YVLFPPAkSLSERLA K228-ub
AQP2 (mouse) YLLFPSTKSLQERLA K228
AQP2 (rat) YLLFPSAKSLQERLA K228
K238
SERLAVLKGLEPDTD
0 1
AQP2 (human) SERLAVLKGLEPDTD K238
AQP2 (mouse) QERLAVLkGLEPDTD K238-ub
AQP2 (rat) QERLAVLKGLEPDTD K238
S256-p
REVRRRQsVELHsPQ
Upstream
Downstream
74 9
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
Effects on Biological Processes:
  • exocytosis, induced
Kinase, in vitro:
  • CK1A (rat)
Putative in vivo kinases:
  • PKACA (human)
Regulatory protein:
  • AVPR2 (human)
  • CHIP (human)
  • PKD1 (human)
  • PPP2CA (human)
Treatment
  • calyculin_A
  • cAMP_analog
  • colforsin
  • dDAVP
  • H-89
  • hypotonic_buffer
  • indometacin
  • NKH_477
  • seliciclib
  • SNP
  • vasopressin
AQP2 (human) REVRRRQsVELHsPQ S256-p
AQP2 (mouse) REVRRRQsVELHsPQ S256-p
AQP2 (rat) REVRRRQsVELHsPQ S256-p
S261-p
RQsVELHsPQsLPRG
Upstream
Downstream
38 9
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
Effects on Biological Processes:
  • exocytosis, induced
Regulatory protein:
  • CHIP (human)
  • PKD1 (human)
Treatment
  • ATP
  • calyculin_A
  • dDAVP
  • desmopressin
  • dopamine
  • FR180204
  • NKH_477
  • seliciclib
  • vasopressin
AQP2 (human) RQsVELHsPQsLPRG S261-p
AQP2 (mouse) RQsVELHsPQsLPRG S261-p
AQP2 (rat) RQsVELHsPQsLPRG S261-p
S264-p
VELHsPQsLPRGtkA
Upstream
Downstream
20 8
Effects on Modified Protein
  • intracellular localization
Effects on Biological Processes:
  • exocytosis, induced
Treatment
  • vasopressin
AQP2 (human) VELHsPQsLPRGtkA S264-p
AQP2 (mouse) VELHsPQsLPRGskA S264-p
AQP2 (rat) VELHsPQsLPRGskA S264-p
T269-p
PQsLPRGtkA_____
Upstream
Downstream
36 5
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
Effects on Biological Processes:
  • endocytosis, inhibited
Kinase, in vitro:
  • ROCK1 (human)
Putative in vivo kinases:
  • ROCK1 (human)
Regulatory protein:
  • AVPR2 (human)
  • CHIP (human)
Treatment
  • NKH_477
  • vasopressin
  • Y27632
AQP2 (human) PQsLPRGtkA_____ T269-p
AQP2 (mouse) PQsLPRGskA_____ S269-p
AQP2 (rat) PQsLPRGskA_____ S269-p
K270-ub
QsLPRGtkA______
Downstream
6 0
Effects on Modified Protein
  • intracellular localization
  • phosphorylation
  • protein degradation
AQP2 (human) QsLPRGtkA______ K270-ub
AQP2 (mouse) QsLPRGskA______ K270-ub
AQP2 (rat) QsLPRGskA______ K270-ub