PXN (human)

LTP

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

HTP

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

S19

ESTTSHISKRPVFLS

PXN (human)	ESTTSHISKRPVFLS	S19
PXN iso2 (human)	ESTTSHIsKRPVFLS	S19-p
PXN iso3 (human)	ESTTSHISKRPVFLS	S19
PXN (mouse)	ESTTSHISKRPVFLs	S19
PXN iso2 (mouse)	ESTTSHISKRPVFLS	S19
PXN (rat)	ESTTSHISKRPVFLS	S19
PXN (chicken)	ESTTSHISKRPVFLT	S19
PXN (cow)	ESTTSHISKRPVFLS	S14

S26

SKRPVFLSEEtPysy

PXN (human)	SKRPVFLSEEtPysy	S26
PXN iso2 (human)	sKRPVFLSEETPySy	S26
PXN iso3 (human)	SKRPVFLSEETPySy	S26
PXN (mouse)	SKRPVFLsEEPPysy	S26-p
PXN iso2 (mouse)	SKRPVFLSEEPPYSY	S26
PXN (rat)	SKRPVFLSEEPPySY	S26
PXN (chicken)	SKRPVFLTEEtPySY	T26
PXN (cow)	SKRPVFLSEETPYSY	S21

T29-p

PVFLSEEtPysyPtG

PXN (human)	PVFLSEEtPysyPtG	T29-p
PXN iso2 (human)	PVFLSEETPySyPTG	T29
PXN iso3 (human)	PVFLSEETPySyPTG	T29
PXN (mouse)	PVFLsEEPPysyPTG	P29
PXN iso2 (mouse)	PVFLSEEPPYSYPTG	P29
PXN (rat)	PVFLSEEPPySYPTG	P29
PXN (chicken)	PVFLTEEtPySYPTG	T29-p
PXN (cow)	PVFLSEETPYSYPTG	T24

Y31-p

FLSEEtPysyPtGNH

Upstream

Downstream

Effects on Modified Protein

intracellular localization
molecular association, regulation
phosphorylation

Effects on Biological Processes:

carcinogenesis, induced
cell growth, induced
cell motility, induced
cytoskeletal reorganization

Kinase, in vitro:

Fyn (human)

Putative in vivo kinases:

Abl (human)
Fyn (human)

Regulatory protein:

Fyn (human)
MIEN1 (human)
PXN (human)
SHP-2 (human)
ULK1 (human)

Treatment

EPA
hesperetin
HGF
light
PP1
PP2
PP3
serum
siRNA
sphingosine_1-phosphate
stiff ECM substrate
TGF-beta

PXN (human)	FLSEEtPysyPtGNH	Y31-p
PXN iso2 (human)	FLSEETPySyPTGNH	Y31-p
PXN iso3 (human)	FLSEETPySyPTGNH	Y31-p
PXN (mouse)	FLsEEPPysyPTGNH	Y31-p
PXN iso2 (mouse)	FLSEEPPYSYPTGNH	Y31
PXN (rat)	FLSEEPPySYPTGNH	Y31-p
PXN (chicken)	FLTEEtPySYPTGNH	Y31-p
PXN (cow)	FLSEETPYSYPTGNH	Y26

S32-p

LSEEtPysyPtGNHt

Upstream

Downstream

Effects on Modified Protein

molecular association, regulation

Effects on Biological Processes:

carcinogenesis, inhibited
cell motility, inhibited
cytoskeletal reorganization

Kinase, in vitro:

ULK1 (human)
ULK2 (human)

Putative in vivo kinases:

ULK1 (human)
ULK2 (human)

Treatment

(-)-Blebbistatin
Rho activator II
SBI-0206965
siRNA
stiff ECM substrate

PXN (human)	LSEEtPysyPtGNHt	S32-p
PXN iso2 (human)	LSEETPySyPTGNHT	S32
PXN iso3 (human)	LSEETPySyPTGNHT	S32
PXN (mouse)	LsEEPPysyPTGNHt	S32-p
PXN iso2 (mouse)	LSEEPPYSYPTGNHT	S32
PXN (rat)	LSEEPPySYPTGNHT	S32
PXN (chicken)	LTEEtPySYPTGNHT	S32
PXN (cow)	LSEETPYSYPTGNHT	S27

Y33-p

SEEtPysyPtGNHty

PXN (human)	SEEtPysyPtGNHty	Y33-p
PXN iso2 (human)	SEETPySyPTGNHTy	Y33-p
PXN iso3 (human)	SEETPySyPTGNHTy	Y33-p
PXN (mouse)	sEEPPysyPTGNHty	Y33-p
PXN iso2 (mouse)	SEEPPYSYPTGNHTY	Y33
PXN (rat)	SEEPPySYPTGNHTY	Y33
PXN (chicken)	TEEtPySYPTGNHTy	Y33
PXN (cow)	SEETPYSYPTGNHTY	Y28

T35-p

EtPysyPtGNHtyQE

PXN (human)	EtPysyPtGNHtyQE	T35-p
PXN iso2 (human)	ETPySyPTGNHTyQE	T35
PXN iso3 (human)	ETPySyPTGNHTyQE	T35
PXN (mouse)	EPPysyPTGNHtyQE	T35
PXN iso2 (mouse)	EPPYSYPTGNHTYQE	T35
PXN (rat)	EPPySYPTGNHTYQE	T35
PXN (chicken)	EtPySYPTGNHTyQE	T35
PXN (cow)	ETPYSYPTGNHTYQE	T30

T39-p

syPtGNHtyQEIAVP

PXN (human)	syPtGNHtyQEIAVP	T39-p
PXN iso2 (human)	SyPTGNHTyQEIAVP	T39
PXN iso3 (human)	SyPTGNHTyQEIAVP	T39
PXN (mouse)	syPTGNHtyQEIAVP	T39-p
PXN iso2 (mouse)	SYPTGNHTYQEIAVP	T39
PXN (rat)	SYPTGNHTYQEIAVP	T39
PXN (chicken)	SYPTGNHTyQEIAVP	T39
PXN (cow)	SYPTGNHTYQEIAVP	T34

Y40-p

yPtGNHtyQEIAVPP

PXN (human)	yPtGNHtyQEIAVPP	Y40-p
PXN iso2 (human)	yPTGNHTyQEIAVPP	Y40-p
PXN iso3 (human)	yPTGNHTyQEIAVPP	Y40-p
PXN (mouse)	yPTGNHtyQEIAVPP	Y40-p
PXN iso2 (mouse)	YPTGNHTYQEIAVPP	Y40
PXN (rat)	YPTGNHTYQEIAVPP	Y40
PXN (chicken)	YPTGNHTyQEIAVPP	Y40-p
PXN (cow)	YPTGNHTYQEIAVPP	Y35

S74

DQWQPSSSRFIHQQP

PXN (human)	DQWQPSSSRFIHQQP	S74
PXN iso2 (human)	DQWQPSSsRFIHQQP	S74-gl
PXN iso3 (human)	DQWQPSSSRFIHQQP	S74
PXN (mouse)	DQWQPSGSRyAHQQP	S74
PXN iso2 (mouse)	DQWQPSGSRYAHQQP	S74
PXN (rat)	DQWQPSGSRyAHQQP	S74
PXN (chicken)	DQWQPSVSRyGHQQP	S74
PXN (cow)	DPWPPSTSRFTHQQP	S68

F76

WQPSSSRFIHQQPQs

PXN (human)	WQPSSSRFIHQQPQs	F76
PXN iso2 (human)	WQPSSsRFIHQQPQs	F76
PXN iso3 (human)	WQPSSSRFIHQQPQS	F76
PXN (mouse)	WQPSGSRyAHQQPPs	Y76-p
PXN iso2 (mouse)	WQPSGSRYAHQQPPS	Y76
PXN (rat)	WQPSGSRyAHQQPPs	Y76-p
PXN (chicken)	WQPSVSRyGHQQPQs	Y76-p
PXN (cow)	WPPSTSRFTHQQPQS	F70

S83-p

FIHQQPQsssPVyGs

Upstream

Treatment

antibody
U0126

PXN (human)	FIHQQPQsssPVyGs	S83-p
PXN iso2 (human)	FIHQQPQsssPVyGs	S83-p
PXN iso3 (human)	FIHQQPQSSsPVyGS	S83
PXN (mouse)	yAHQQPPsPLPVyss	S83-p
PXN iso2 (mouse)	YAHQQPPSPLPVYSS	S83
PXN (rat)	yAHQQPPsPSPIySS	S83-p
PXN (chicken)	yGHQQPQsQsPIyss	S83-p
PXN (cow)	FTHQQPQSSSPVYGS	S77

S83

FIHQQPQSssPVyGs

PXN (human)	FIHQQPQSssPVyGs	S83
PXN iso2 (human)	FIHQQPQsssPVyGs	S83-gl
PXN iso3 (human)	FIHQQPQSSsPVyGS	S83
PXN (mouse)	yAHQQPPSPLPVyss	S83
PXN iso2 (mouse)	YAHQQPPSPLPVYSS	S83
PXN (rat)	yAHQQPPSPSPIySS	S83
PXN (chicken)	yGHQQPQSQsPIyss	S83
PXN (cow)	FTHQQPQSSSPVYGS	S77

S84-p

IHQQPQsssPVyGsS

Upstream

Treatment

FGF2

PXN (human)	IHQQPQsssPVyGsS	S84-p
PXN iso2 (human)	IHQQPQsssPVyGss	S84-p
PXN iso3 (human)	IHQQPQSSsPVyGSS	S84
PXN (mouse)	AHQQPPsPLPVysss	P84
PXN iso2 (mouse)	AHQQPPSPLPVYSSS	P84
PXN (rat)	AHQQPPsPSPIySSS	P84
PXN (chicken)	GHQQPQsQsPIysss	Q84
PXN (cow)	THQQPQSSSPVYGSS	S78

S84

IHQQPQsSsPVyGsS

PXN (human)	IHQQPQsSsPVyGsS	S84
PXN iso2 (human)	IHQQPQsssPVyGss	S84-gl
PXN iso3 (human)	IHQQPQSSsPVyGSS	S84
PXN (mouse)	AHQQPPsPLPVysss	P84
PXN iso2 (mouse)	AHQQPPSPLPVYSSS	P84
PXN (rat)	AHQQPPsPSPIySSS	P84
PXN (chicken)	GHQQPQsQsPIysss	Q84
PXN (cow)	THQQPQSSSPVYGSS	S78

S85-p

HQQPQsssPVyGsSA

Upstream

Downstream

660

Effects on Modified Protein

intracellular localization
molecular association, regulation

Effects on Biological Processes:

cell adhesion, altered
cell motility, induced
cytoskeletal reorganization

Kinase, in vitro:

CDK5 (human)
P38A (human)

Putative in vivo kinases:

P38A (human)

Regulatory protein:

PXN (human)

Treatment

cell_adhesion
erlotinib
FGF2
HGF
lapatinib
NGF
SB202190
SB203580
seliciclib

PXN (human)	HQQPQsssPVyGsSA	S85-p
PXN iso2 (human)	HQQPQsssPVyGssA	S85-p
PXN iso3 (human)	HQQPQSSsPVyGSSA	S85-p
PXN (mouse)	HQQPPsPLPVysssA	L85
PXN iso2 (mouse)	HQQPPSPLPVYSSSA	L85
PXN (rat)	HQQPPsPSPIySSST	S85
PXN (chicken)	HQQPQsQsPIysssA	S85-p
PXN (cow)	HQQPQSSSPVYGSSA	S79

S85

HQQPQssSPVyGsSA

PXN (human)	HQQPQssSPVyGsSA	S85
PXN iso2 (human)	HQQPQsssPVyGssA	S85-gl
PXN iso3 (human)	HQQPQSSSPVyGSSA	S85
PXN (mouse)	HQQPPsPLPVysssA	L85
PXN iso2 (mouse)	HQQPPSPLPVYSSSA	L85
PXN (rat)	HQQPPsPSPIySSST	S85
PXN (chicken)	HQQPQsQSPIysssA	S85
PXN (cow)	HQQPQSSSPVYGSSA	S79

Y88-p

PQsssPVyGsSAKTs

Upstream

Downstream

1384

Effects on Biological Processes:

carcinogenesis, induced
cell growth, induced
cell motility, induced
cytoskeletal reorganization

Putative in vivo kinases:

Src (human)

Regulatory protein:

Fyn (human)

Treatment

EPA
erlotinib
FGF2
hesperetin
HGF
LPA
PP1
PP2
PP3
TGF-beta

PXN (human)	PQsssPVyGsSAKTs	Y88-p
PXN iso2 (human)	PQsssPVyGssAKTs	Y88-p
PXN iso3 (human)	PQSSsPVyGSSAKTS	Y88-p
PXN (mouse)	PPsPLPVysssAKNS	Y88-p
PXN iso2 (mouse)	PPSPLPVYSSSAKNS	Y88
PXN (rat)	PPsPSPIySSSTKNS	Y88-p
PXN (chicken)	PQsQsPIysssAKss	Y88-p
PXN (cow)	PQSSSPVYGSSAKTS	Y82

G89

QsssPVyGsSAKTsS

PXN (human)	QsssPVyGsSAKTsS	G89
PXN iso2 (human)	QsssPVyGssAKTss	G89
PXN iso3 (human)	QSSsPVyGSSAKTSS	G89
PXN (mouse)	PsPLPVysssAKNSS	S89-p
PXN iso2 (mouse)	PSPLPVYSSSAKNSS	S89
PXN (rat)	PsPSPIySSSTKNSS	S89
PXN (chicken)	QsQsPIysssAKsss	S89-p
PXN (cow)	QSSSPVYGSSAKTSS	G83

S90-p

sssPVyGsSAKTsSV

PXN (human)	sssPVyGsSAKTsSV	S90-p
PXN iso2 (human)	sssPVyGssAKTssV	S90-p
PXN iso3 (human)	SSsPVyGSSAKTSSV	S90
PXN (mouse)	sPLPVysssAKNSSA	S90-p
PXN iso2 (mouse)	SPLPVYSSSAKNSSA	S90
PXN (rat)	sPSPIySSSTKNSSA	S90
PXN (chicken)	sQsPIysssAKsssA	S90-p
PXN (cow)	SSSPVYGSSAKTSSA	S84

S91

ssPVyGsSAKTsSVS

PXN (human)	ssPVyGsSAKTsSVS	S91
PXN iso2 (human)	ssPVyGssAKTssVs	S91-p
PXN iso3 (human)	SsPVyGSSAKTSSVS	S91
PXN (mouse)	PLPVysssAKNSSAS	S91-p
PXN iso2 (mouse)	PLPVYSSSAKNSSAS	S91
PXN (rat)	PSPIySSSTKNSSAS	S91
PXN (chicken)	QsPIysssAKsssAs	S91-p
PXN (cow)	SSPVYGSSAKTSSAS	S85

T94

VyGsSAKTsSVSNPQ

PXN (human)	VyGsSAKTsSVSNPQ	T94
PXN iso2 (human)	VyGssAKTssVsNPQ	T94
PXN iso3 (human)	VyGSSAKTSSVSNPQ	T94
PXN (mouse)	VysssAKNSSASNTQ	N94
PXN iso2 (mouse)	VYSSSAKNSSASNTQ	N94
PXN (rat)	IySSSTKNSSASNPQ	N94
PXN (chicken)	IysssAKsssAsVPR	S94-p
PXN (cow)	VYGSSAKTSSASNPQ	T88

S95-p

yGsSAKTsSVSNPQD

PXN (human)	yGsSAKTsSVSNPQD	S95-p
PXN iso2 (human)	yGssAKTssVsNPQD	S95-p
PXN iso3 (human)	yGSSAKTSSVSNPQD	S95
PXN (mouse)	ysssAKNSSASNTQD	S95
PXN iso2 (mouse)	YSSSAKNSSASNTQD	S95
PXN (rat)	ySSSTKNSSASNPQD	S95
PXN (chicken)	ysssAKsssAsVPRD	S95-p
PXN (cow)	YGSSAKTSSASNPQD	S89

S96

GsSAKTsSVSNPQDs

PXN (human)	GsSAKTsSVSNPQDs	S96
PXN iso2 (human)	GssAKTssVsNPQDs	S96-p
PXN iso3 (human)	GSSAKTSSVSNPQDS	S96
PXN (mouse)	sssAKNSSASNTQDG	S96
PXN iso2 (mouse)	SSSAKNSSASNTQDG	S96
PXN (rat)	SSSTKNSSASNPQDS	S96
PXN (chicken)	sssAKsssAsVPRDG	S96-p
PXN (cow)	GSSAKTSSASNPQDG	S90

S98

SAKTsSVSNPQDsVG

PXN (human)	SAKTsSVSNPQDsVG	S98
PXN iso2 (human)	sAKTssVsNPQDsVG	S98-p
PXN iso3 (human)	SAKTSSVSNPQDSVG	S98
PXN (mouse)	sAKNSSASNTQDGVG	S98
PXN iso2 (mouse)	SAKNSSASNTQDGVG	S98
PXN (rat)	STKNSSASNPQDSVG	S98
PXN (chicken)	sAKsssAsVPRDGLS	S98-p
PXN (cow)	SAKTSSASNPQDGGG	S92

S103-p

SVSNPQDsVGsPCsR

PXN (human)	SVSNPQDsVGsPCsR	S103-p
PXN iso2 (human)	sVsNPQDsVGsPCsR	S103-p
PXN iso3 (human)	SVSNPQDSVGSPCSR	S103
PXN (mouse)	SASNTQDGVGsLCSR	G103
PXN iso2 (mouse)	SASNTQDGVGSLCSR	G103
PXN (rat)	SASNPQDSVGsLCsR	S103
PXN (chicken)	sAsVPRDGLSsPsPR	G103
PXN (cow)	SASNPQDGGGPPCPR	G97

S106-p

NPQDsVGsPCsRVGE

Upstream

Regulatory protein:

PRP4 (human)

Treatment

ischemia
selumetinib
STLC
vemurafenib

PXN (human)	NPQDsVGsPCsRVGE	S106-p
PXN iso2 (human)	NPQDsVGsPCsRVGE	S106-p
PXN iso3 (human)	NPQDSVGSPCSRVGE	S106
PXN (mouse)	NTQDGVGsLCSRAGE	S106-p
PXN iso2 (mouse)	NTQDGVGSLCSRAGE	S106
PXN (rat)	NPQDSVGsLCsRAGE	S106-p
PXN (chicken)	VPRDGLSsPsPRAsE	S106-p
PXN (cow)	NPQDGGGPPCPRAGE	P100

C108

QDsVGsPCsRVGEEE

PXN (human)	QDsVGsPCsRVGEEE	C108
PXN iso2 (human)	QDsVGsPCsRVGEEE	C108
PXN iso3 (human)	QDSVGSPCSRVGEEE	C108
PXN (mouse)	QDGVGsLCSRAGEEE	C108
PXN iso2 (mouse)	QDGVGSLCSRAGEEE	C108
PXN (rat)	QDSVGsLCsRAGEEE	C108
PXN (chicken)	RDGLSsPsPRAsEEE	S108-p
PXN (cow)	QDGGGPPCPRAGEED	C102

S109-p

DsVGsPCsRVGEEEH

Upstream

Treatment

STLC

PXN (human)	DsVGsPCsRVGEEEH	S109-p
PXN iso2 (human)	DsVGsPCsRVGEEEH	S109-p
PXN iso3 (human)	DSVGSPCSRVGEEEH	S109
PXN (mouse)	DGVGsLCSRAGEEEH	S109
PXN iso2 (mouse)	DGVGSLCSRAGEEEH	S109
PXN (rat)	DSVGsLCsRAGEEEH	S109-p
PXN (chicken)	DGLSsPsPRAsEEEH	P109
PXN (cow)	DGGGPPCPRAGEEDH	P103

G112

GsPCsRVGEEEHVys

PXN (human)	GsPCsRVGEEEHVys	G112
PXN iso2 (human)	GsPCsRVGEEEHVys	G112
PXN iso3 (human)	GSPCSRVGEEEHVyS	G112
PXN (mouse)	GsLCSRAGEEEHVys	G112
PXN iso2 (mouse)	GSLCSRAGEEEHVyS	G112
PXN (rat)	GsLCsRAGEEEHVyS	G112
PXN (chicken)	SsPsPRAsEEEHVys	S112-p
PXN (cow)	GPPCPRAGEEDHVYS	G106

Y118-p

VGEEEHVysFPNkQk

Upstream

Downstream

2588

PXN (human)
Y118-p

PXN iso2 (human)
Y118-p

PXN iso3 (human)
Y118-p

PXN (mouse)
Y118-p

PXN iso2 (mouse)
Y118-p

PXN (rat)
Y118-p

PXN (chicken)
Y118-p

69363 : Phospho-Paxillin (Tyr118) (E9U9F) Rabbit mAb

Effects on Modified Protein

intracellular localization
molecular association, regulation
phosphorylation

Effects on Biological Processes:

autophagy, induced
carcinogenesis, induced
cell adhesion, induced
cell adhesion, inhibited
cell differentiation, inhibited
cell growth, induced
cell motility, induced
cytoskeletal reorganization
signaling pathway regulation

Phosphatases, in vitro:

SHP-2 (human)

Putative in vivo kinases:

Abl (human)
FAK (human)

Regulatory protein:

EED (human)
ERK1 (human)
GRP78 (human)
ITGA6 (human)
JAM-A (human)
KARS (human)
Lck (human)
MAGI1 (human)
MYH9 (human)
NEK5 (human)
PDCD10 (human)
PKCD (human)
PXN (human)
ROCK2 (human)
SHP-2 (human)
skMLCK (human)
TM4SF5 (human)
TXNDC12 (human)
ULK1 (human)

Treatment

alpha2-macroglobulin
CI1040
cilengitide
defactinib
dexamethasone
EGF
erlotinib
fibronectin
fluid_shear_stress
H2O2
heating
hesperetin
HGF
IBMX
light
PF562271
PGE2
PP2
SB202190
sphingosine_1-phosphate
stiff ECM substrate
TCDD
TGF-beta
U0126
vanadate

PXN (human)	VGEEEHVysFPNkQk	Y118-p
PXN iso2 (human)	VGEEEHVysFPNKQK	Y118-p
PXN iso3 (human)	VGEEEHVySFPNKQK	Y118-p
PXN (mouse)	AGEEEHVysFPNKQk	Y118-p
PXN iso2 (mouse)	AGEEEHVySFPNKQK	Y118-p
PXN (rat)	AGEEEHVySFPNKQK	Y118-p
PXN (chicken)	AsEEEHVysFPNKQK	Y118-p
PXN (cow)	AGEEDHVYSFPNKQK	Y112

S119-p

GEEEHVysFPNkQks

Upstream

Downstream

118

Effects on Modified Protein

molecular association, regulation

Effects on Biological Processes:

carcinogenesis, inhibited
cell motility, inhibited
cytoskeletal reorganization

Kinase, in vitro:

ULK1 (human)
ULK2 (human)

Putative in vivo kinases:

ULK1 (human)
ULK2 (human)

Treatment

(-)-Blebbistatin
Rho activator II
SBI-0206965
siRNA
stiff ECM substrate

PXN (human)	GEEEHVysFPNkQks	S119-p
PXN iso2 (human)	GEEEHVysFPNKQKs	S119-p
PXN iso3 (human)	GEEEHVySFPNKQKS	S119
PXN (mouse)	GEEEHVysFPNKQks	S119-p
PXN iso2 (mouse)	GEEEHVySFPNKQKS	S119
PXN (rat)	GEEEHVySFPNKQKs	S119
PXN (chicken)	sEEEHVysFPNKQKs	S119-p
PXN (cow)	GEEDHVYSFPNKQKS	S113

K123-ub

HVysFPNkQksAEPs

PXN (human)	HVysFPNkQksAEPs	K123-ub
PXN iso2 (human)	HVysFPNKQKsAEPs	K123
PXN iso3 (human)	HVySFPNKQKSAEPS	K123
PXN (mouse)	HVysFPNKQksAEPs	K123
PXN iso2 (mouse)	HVySFPNKQKSAEPS	K123
PXN (rat)	HVySFPNKQKsAEPs	K123
PXN (chicken)	HVysFPNKQKsAEPs	K123
PXN (cow)	HVYSFPNKQKSAEPS	K117

K125-ub

ysFPNkQksAEPsPt

PXN (human)	ysFPNkQksAEPsPt	K125-ub
PXN iso2 (human)	ysFPNKQKsAEPsPt	K125
PXN iso3 (human)	ySFPNKQKSAEPSPT	K125
PXN (mouse)	ysFPNKQksAEPsPt	K125-ub
PXN iso2 (mouse)	ySFPNKQKSAEPSPT	K125
PXN (rat)	ySFPNKQKsAEPsPt	K125
PXN (chicken)	ysFPNKQKsAEPsPT	K125
PXN (cow)	YSFPNKQKSAEPSPT	K119

S126-p

sFPNkQksAEPsPtV

Upstream

Downstream

Effects on Modified Protein

intracellular localization
receptor internalization, induced

Effects on Biological Processes:

cell motility, induced
cytoskeletal reorganization
transcription, induced

Regulatory protein:

ERK2 (human)
JAM-A (human)

Treatment

17-beta-estradiol
AZD1152
BI2536
CI1040
HGF
LY294002
MLN8054
PP1
PP2
selumetinib
U0126
vemurafenib
ZM447439

PXN (human)	sFPNkQksAEPsPtV	S126-p
PXN iso2 (human)	sFPNKQKsAEPsPtV	S126-p
PXN iso3 (human)	SFPNKQKSAEPSPTV	S126
PXN (mouse)	sFPNKQksAEPsPtV	S126-p
PXN iso2 (mouse)	SFPNKQKSAEPSPTV	S126
PXN (rat)	SFPNKQKsAEPsPtV	S126-p
PXN (chicken)	sFPNKQKsAEPsPTM	S126-p
PXN (cow)	SFPNKQKSAEPSPTV	S120

S130-p

kQksAEPsPtVMsts

Upstream

Downstream

Effects on Biological Processes:

cell motility, induced
cytoskeletal reorganization

Treatment

antibody
dasatinib
U0126

PXN (human)	kQksAEPsPtVMsts	S130-p
PXN iso2 (human)	KQKsAEPsPtVMSts	S130-p
PXN iso3 (human)	KQKSAEPSPTVMSTS	S130
PXN (mouse)	KQksAEPsPtVMsss	S130-p
PXN iso2 (mouse)	KQKSAEPSPTVMSSS	S130
PXN (rat)	KQKsAEPsPtVMSss	S130-p
PXN (chicken)	KQKsAEPsPTMTSTs	S130-p
PXN (cow)	KQKSAEPSPTVMSSS	S124

T132-p

ksAEPsPtVMstsLG

PXN (human)	ksAEPsPtVMstsLG	T132-p
PXN iso2 (human)	KsAEPsPtVMStsLG	T132-p
PXN iso3 (human)	KSAEPSPTVMSTSLG	T132
PXN (mouse)	ksAEPsPtVMsssLG	T132-p
PXN iso2 (mouse)	KSAEPSPTVMSSSLG	T132
PXN (rat)	KsAEPsPtVMSssLG	T132-p
PXN (chicken)	KsAEPsPTMTSTsLG	T132
PXN (cow)	KSAEPSPTVMSSSLG	T126

S135-p

EPsPtVMstsLGsNL

PXN (human)	EPsPtVMstsLGsNL	S135-p
PXN iso2 (human)	EPsPtVMStsLGSNL	S135
PXN iso3 (human)	EPSPTVMSTSLGSNL	S135
PXN (mouse)	EPsPtVMsssLGsNL	S135-p
PXN iso2 (mouse)	EPSPTVMSSSLGSNL	S135
PXN (rat)	EPsPtVMSssLGSNL	S135
PXN (chicken)	EPsPTMTSTsLGSNL	S135
PXN (cow)	EPSPTVMSSSLGSNL	S129

T136-p

PsPtVMstsLGsNLs

PXN (human)	PsPtVMstsLGsNLs	T136-p
PXN iso2 (human)	PsPtVMStsLGSNLs	T136-p
PXN iso3 (human)	PSPTVMSTSLGSNLS	T136
PXN (mouse)	PsPtVMsssLGsNLs	S136-p
PXN iso2 (mouse)	PSPTVMSSSLGSNLS	S136
PXN (rat)	PsPtVMSssLGSNLs	S136-p
PXN (chicken)	PsPTMTSTsLGSNLs	T136
PXN (cow)	PSPTVMSSSLGSNLS	S130

S137-p

sPtVMstsLGsNLsE

PXN (human)	sPtVMstsLGsNLsE	S137-p
PXN iso2 (human)	sPtVMStsLGSNLsE	S137-p
PXN iso3 (human)	SPTVMSTSLGSNLSE	S137
PXN (mouse)	sPtVMsssLGsNLsE	S137-p
PXN iso2 (mouse)	SPTVMSSSLGSNLSE	S137
PXN (rat)	sPtVMSssLGSNLsE	S137-p
PXN (chicken)	sPTMTSTsLGSNLsE	S137-p
PXN (cow)	SPTVMSSSLGSNLSE	S131

S140-p

VMstsLGsNLsELDR

PXN (human)	VMstsLGsNLsELDR	S140-p
PXN iso2 (human)	VMStsLGSNLsELDR	S140
PXN iso3 (human)	VMSTSLGSNLSELDR	S140
PXN (mouse)	VMsssLGsNLsELDR	S140-p
PXN iso2 (mouse)	VMSSSLGSNLSELDR	S140
PXN (rat)	VMSssLGSNLsELDR	S140
PXN (chicken)	MTSTsLGSNLsELDR	S140
PXN (cow)	VMSSSLGSNLSELDR	S134

S143-p

tsLGsNLsELDRLLL

PXN (human)	tsLGsNLsELDRLLL	S143-p
PXN iso2 (human)	tsLGSNLsELDRLLL	S143-p
PXN iso3 (human)	TSLGSNLSELDRLLL	S143
PXN (mouse)	ssLGsNLsELDRLLL	S143-p
PXN iso2 (mouse)	SSLGSNLSELDRLLL	S143
PXN (rat)	ssLGSNLsELDRLLL	S143-p
PXN (chicken)	TsLGSNLsELDRLLL	S143-p
PXN (cow)	SSLGSNLSELDRLLL	S137

gap

PXN (human)	gap	-
PXN iso2 (human)	gap	-
PXN iso3 (human)	gap	-
PXN (mouse)	gap	-
PXN iso2 (mouse)	gap	-
PXN (rat)	QRSPSGFSAGMVSVQ	S163
PXN (chicken)	HNPPSGFsADEVSRs	S164-p
PXN (cow)	gap	-

S170

PADEANSSPPLPGAL

PXN (human)	PADEANSSPPLPGAL	S170
PXN iso2 (human)	PADEANSsPPLPGAL	S170-p
PXN iso3 (human)	PADEANSSPPLPGAL	S170
PXN (mouse)	PADEAESsPPLPGAL	S170-p
PXN iso2 (mouse)	PADEAESSPPLPGAL	S170
PXN (rat)	FQDEAESSPPLPGAL	S199
PXN (chicken)	sADEVSRsPsLPNVT	S171-p
PXN (cow)	PADEANSSPPLPGPL	S164

P172

DEANSSPPLPGALsP

PXN (human)	DEANSSPPLPGALsP	P172
PXN iso2 (human)	DEANSsPPLPGALsP	P172
PXN iso3 (human)	DEANSSPPLPGALSP	P172
PXN (mouse)	DEAESsPPLPGALsP	P172
PXN iso2 (mouse)	DEAESSPPLPGALSP	P172
PXN (rat)	DEAESSPPLPGALSP	P201
PXN (chicken)	DEVSRsPsLPNVTGP	S173-p
PXN (cow)	DEANSSPPLPGPLST	P166

S178-p

PPLPGALsPLyGVPE

Upstream

Downstream

Effects on Biological Processes:

cell adhesion, altered
cell motility, altered
cytoskeletal reorganization

Kinase, in vitro:

JNK1 (human)

Putative in vivo kinases:

JNK1 (human)

Regulatory protein:

TGM2 (human)

Treatment

EGF
SP600125

PXN (human)	PPLPGALsPLyGVPE	S178-p
PXN iso2 (human)	PPLPGALsPLyGVPE	S178-p
PXN iso3 (human)	PPLPGALSPLYGVPE	S178
PXN (mouse)	PPLPGALsPLyGIPE	S178-p
PXN iso2 (mouse)	PPLPGALSPLYGIPE	S178
PXN (rat)	PPLPGALSPLYGVPE	S207
PXN (chicken)	PsLPNVTGPHyVIPE	G179
PXN (cow)	PPLPGPLSTHYGVPE	S172

Y181-p

PGALsPLyGVPETNs

Upstream

Treatment

serum
TGF-beta

PXN (human)	PGALsPLyGVPETNs	Y181-p
PXN iso2 (human)	PGALsPLyGVPEtNS	Y181-p
PXN iso3 (human)	PGALSPLYGVPETNS	Y181
PXN (mouse)	PGALsPLyGIPENNT	Y181-p
PXN iso2 (mouse)	PGALSPLYGIPENNT	Y181
PXN (rat)	PGALSPLYGVPESNN	Y210
PXN (chicken)	PNVTGPHyVIPEsss	Y182-p
PXN (cow)	PGPLSTHYGVPENNS	Y175

T186

PLyGVPETNsPLGGK

PXN (human)	PLyGVPETNsPLGGK	T186
PXN iso2 (human)	PLyGVPEtNSPLGGK	T186-p
PXN iso3 (human)	PLYGVPETNSPLGGK	T186
PXN (mouse)	PLyGIPENNTPLGGK	N186
PXN iso2 (mouse)	PLYGIPENNTPLGGK	N186
PXN (rat)	PLYGVPESNNLLGGK	S215
PXN (chicken)	PHyVIPEssssAGGK	S187-p
PXN (cow)	THYGVPENNSLLGGK	N180

N187

LyGVPETNsPLGGKA

PXN (human)	LyGVPETNsPLGGKA	N187
PXN iso2 (human)	LyGVPEtNSPLGGKA	N187
PXN iso3 (human)	LYGVPETNSPLGGKA	N187
PXN (mouse)	LyGIPENNTPLGGKA	N187
PXN iso2 (mouse)	LYGIPENNTPLGGKA	N187
PXN (rat)	LYGVPESNNLLGGKA	N216
PXN (chicken)	HyVIPEssssAGGKA	S188-p
PXN (cow)	HYGVPENNSLLGGKA	N181

S188-p

yGVPETNsPLGGKAG

PXN (human)	yGVPETNsPLGGKAG	S188-p
PXN iso2 (human)	yGVPEtNSPLGGKAG	S188
PXN iso3 (human)	YGVPETNSPLGGKAG	S188
PXN (mouse)	yGIPENNTPLGGKAG	T188
PXN iso2 (mouse)	YGIPENNTPLGGKAG	T188
PXN (rat)	YGVPESNNLLGGKAG	N217
PXN (chicken)	yVIPEssssAGGKAA	S189-p
PXN (cow)	YGVPENNSLLGGKAG	S182

P189

GVPETNsPLGGKAGP

PXN (human)	GVPETNsPLGGKAGP	P189
PXN iso2 (human)	GVPEtNSPLGGKAGP	P189
PXN iso3 (human)	GVPETNSPLGGKAGP	P189
PXN (mouse)	GIPENNTPLGGKAGP	P189
PXN iso2 (mouse)	GIPENNTPLGGKAGP	P189
PXN (rat)	GVPESNNLLGGKAGP	L218
PXN (chicken)	VIPEssssAGGKAAP	S190-p
PXN (cow)	GVPENNSLLGGKAGA	L183

T198

GGKAGPLTKEKPKRN

PXN (human)	GGKAGPLTKEKPKRN	T198
PXN iso2 (human)	GGKAGPLTkEkPkRN	T198
PXN iso3 (human)	GGKAGPLTKEKPKRN	T198
PXN (mouse)	GGKAGPLVKEKPKRN	V198
PXN iso2 (mouse)	GGKAGPLVKEKPKRN	V198
PXN (rat)	GGKAGPLMKEKPKRN	M227
PXN (chicken)	GGKAAPPtKEKPKRN	T199-p
PXN (cow)	GGKAGALTKEKPKRN	T192

K199

GKAGPLTKEKPKRNG

PXN (human)	GKAGPLTKEKPKRNG	K199
PXN iso2 (human)	GKAGPLTkEkPkRNG	K199-ub
PXN iso3 (human)	GKAGPLTKEKPKRNG	K199
PXN (mouse)	GKAGPLVKEKPKRNG	K199
PXN iso2 (mouse)	GKAGPLVKEKPKRNG	K199
PXN (rat)	GKAGPLMKEKPKRNG	K228
PXN (chicken)	GKAAPPtKEKPKRNG	K200
PXN (cow)	GKAGALTKEKPKRNG	K193

K201

AGPLTKEKPKRNGGR

PXN (human)	AGPLTKEKPKRNGGR	K201
PXN iso2 (human)	AGPLTkEkPkRNGGR	K201-ub
PXN iso3 (human)	AGPLTKEKPKRNGGR	K201
PXN (mouse)	AGPLVKEKPKRNGGR	K201
PXN iso2 (mouse)	AGPLVKEKPKRNGGR	K201
PXN (rat)	AGPLMKEKPKRNGGR	K230
PXN (chicken)	AAPPtKEKPKRNGGR	K202
PXN (cow)	AGALTKEKPKRNGGR	K195

K203

PLTKEKPKRNGGRGL

PXN (human)	PLTKEKPKRNGGRGL	K203
PXN iso2 (human)	PLTkEkPkRNGGRGL	K203-ub
PXN iso3 (human)	PLTKEKPKRNGGRGL	K203
PXN (mouse)	PLVKEKPKRNGGRGL	K203
PXN iso2 (mouse)	PLVKEKPKRNGGRGL	K203
PXN (rat)	PLMKEKPKRNGGRGL	K232
PXN (chicken)	PPtKEKPKRNGGRGI	K204
PXN (cow)	ALTKEKPKRNGGRGL	K197

S216

GLEDVRPSVEsLLDE

PXN (human)	GLEDVRPSVEsLLDE	S216
PXN iso2 (human)	GLEDVRPSVESLLDE	S216
PXN iso3 (human)	GLEDVRPSVESLLDE	S216
PXN (mouse)	GLEDVRPSVESLLDE	S216
PXN iso2 (mouse)	GLEDVRPSVESLLDE	S216
PXN (rat)	GLEDVRPSVESLLDE	S245
PXN (chicken)	GIEDVRPsVEsLLDE	S217-p
PXN (cow)	GLEDLRPSVENLLDE	S210

S219-p

DVRPSVEsLLDELES

PXN (human)	DVRPSVEsLLDELES	S219-p
PXN iso2 (human)	DVRPSVESLLDELES	S219
PXN iso3 (human)	DVRPSVESLLDELES	S219
PXN (mouse)	DVRPSVESLLDELES	S219
PXN iso2 (mouse)	DVRPSVESLLDELES	S219
PXN (rat)	DVRPSVESLLDELEN	S248
PXN (chicken)	DVRPsVEsLLDELEs	S220-p
PXN (cow)	DLRPSVENLLDELES	N213

S226

sLLDELESSVPsPVP

PXN (human)	sLLDELESSVPsPVP	S226
PXN iso2 (human)	SLLDELESSVPsPVP	S226
PXN iso3 (human)	SLLDELESSVPSPVP	S226
PXN (mouse)	SLLDELESSVPSPVP	S226
PXN iso2 (mouse)	SLLDELESSVPSPVP	S226
PXN (rat)	SLLDELENSVPsPVP	N255
PXN (chicken)	sLLDELEssVPsPVP	S227-p
PXN (cow)	NLLDELESSVPSPVP	S220

S227

LLDELESSVPsPVPA

PXN (human)	LLDELESSVPsPVPA	S227
PXN iso2 (human)	LLDELESSVPsPVPA	S227
PXN iso3 (human)	LLDELESSVPSPVPA	S227
PXN (mouse)	LLDELESSVPSPVPA	S227
PXN iso2 (mouse)	LLDELESSVPSPVPA	S227
PXN (rat)	LLDELENSVPsPVPA	S256
PXN (chicken)	LLDELEssVPsPVPA	S228-p
PXN (cow)	LLDELESSVPSPVPT	S221

S230-p

ELESSVPsPVPAITV

PXN (human)	ELESSVPsPVPAITV	S230-p
PXN iso2 (human)	ELESSVPsPVPAItV	S230-p
PXN iso3 (human)	ELESSVPSPVPAITV	S230
PXN (mouse)	ELESSVPSPVPAITV	S230
PXN iso2 (mouse)	ELESSVPSPVPAITV	S230
PXN (rat)	ELENSVPsPVPAITV	S259-p
PXN (chicken)	ELEssVPsPVPAITV	S231-p
PXN (cow)	ELESSVPSPVPTITV	S224

T236

PsPVPAITVNQGEMs

PXN (human)	PsPVPAITVNQGEMs	T236
PXN iso2 (human)	PsPVPAItVNQGEMS	T236-p
PXN iso3 (human)	PSPVPAITVNQGEMS	T236
PXN (mouse)	PSPVPAITVNQGEMS	T236
PXN iso2 (mouse)	PSPVPAITVNQGEMS	T236
PXN (rat)	PsPVPAITVNQGEMS	T265
PXN (chicken)	PsPVPAITVsQGEVS	T237
PXN (cow)	PSPVPTITVNQGEMS	T230

N238

PVPAITVNQGEMssP

PXN (human)	PVPAITVNQGEMssP	N238
PXN iso2 (human)	PVPAItVNQGEMSsP	N238
PXN iso3 (human)	PVPAITVNQGEMSSP	N238
PXN (mouse)	PVPAITVNQGEMSsP	N238
PXN iso2 (mouse)	PVPAITVNQGEMSSP	N238
PXN (rat)	PVPAITVNQGEMSSP	N267
PXN (chicken)	PVPAITVsQGEVSsP	S239-p
PXN (cow)	PVPTITVNQGEMSSP	N232

S243-p

TVNQGEMssPQRVts

PXN (human)	TVNQGEMssPQRVts	S243-p
PXN iso2 (human)	tVNQGEMSsPQRVts	S243
PXN iso3 (human)	TVNQGEMSSPQRVts	S243
PXN (mouse)	TVNQGEMSsPQRVTs	S243
PXN iso2 (mouse)	TVNQGEMSSPQRVTS	S243
PXN (rat)	TVNQGEMSSPQRVTS	S272
PXN (chicken)	TVsQGEVSsPQRVNA	S244
PXN (cow)	TVNQGEMSSPQRVTS	S237

S244-p

VNQGEMssPQRVtst

PXN (human)	VNQGEMssPQRVtst	S244-p
PXN iso2 (human)	VNQGEMSsPQRVtst	S244-p
PXN iso3 (human)	VNQGEMSSPQRVtst	S244
PXN (mouse)	VNQGEMSsPQRVTsS	S244-p
PXN iso2 (mouse)	VNQGEMSSPQRVTSS	S244
PXN (rat)	VNQGEMSSPQRVTSS	S273
PXN (chicken)	VsQGEVSsPQRVNAS	S245-p
PXN (cow)	VNQGEMSSPQRVTSS	S238

T249-p

MssPQRVtstQQQtR

PXN (human)	MssPQRVtstQQQtR	T249-p
PXN iso2 (human)	MSsPQRVtstQQQtR	T249-p
PXN iso3 (human)	MSSPQRVtstQQQTR	T249-p
PXN (mouse)	MSsPQRVTsSQQQTR	T249
PXN iso2 (mouse)	MSSPQRVTSSQQQTR	T249
PXN (rat)	MSSPQRVTSSQQQTR	T278
PXN (chicken)	VSsPQRVNASQQQTR	N250
PXN (cow)	MSSPQRVTSSQQQTR	T243

S250-p

ssPQRVtstQQQtRI

PXN (human)	ssPQRVtstQQQtRI	S250-p
PXN iso2 (human)	SsPQRVtstQQQtRI	S250-p
PXN iso3 (human)	SSPQRVtstQQQTRI	S250-p
PXN (mouse)	SsPQRVTsSQQQTRI	S250-p
PXN iso2 (mouse)	SSPQRVTSSQQQTRI	S250
PXN (rat)	SSPQRVTSSQQQTRI	S279
PXN (chicken)	SsPQRVNASQQQTRI	A251
PXN (cow)	SSPQRVTSSQQQTRI	S244

T251-p

sPQRVtstQQQtRIs

PXN (human)	sPQRVtstQQQtRIs	T251-p
PXN iso2 (human)	sPQRVtstQQQtRIs	T251-p
PXN iso3 (human)	SPQRVtstQQQTRIs	T251-p
PXN (mouse)	sPQRVTsSQQQTRIs	S251
PXN iso2 (mouse)	SPQRVTSSQQQTRIS	S251
PXN (rat)	SPQRVTSSQQQTRIs	S280
PXN (chicken)	sPQRVNASQQQTRIs	S252
PXN (cow)	SPQRVTSSQQQTRIs	S245

T255-p

VtstQQQtRIsAssA

PXN (human)	VtstQQQtRIsAssA	T255-p
PXN iso2 (human)	VtstQQQtRIsAssA	T255-p
PXN iso3 (human)	VtstQQQTRIsAssA	T255
PXN (mouse)	VTsSQQQTRIsAssA	T255
PXN iso2 (mouse)	VTSSQQQTRISASSA	T255
PXN (rat)	VTSSQQQTRIsASsA	T284
PXN (chicken)	VNASQQQTRIsASsA	T256
PXN (cow)	VTSSQQQTRIsASSA	T249

S258-p

tQQQtRIsAssAtRE

Upstream

Downstream

Effects on Modified Protein

molecular association, regulation

Putative in vivo kinases:

PAK1 (human)

Treatment

angiotensin-(1-7)
EGF

PXN (human)	tQQQtRIsAssAtRE	S258-p
PXN iso2 (human)	tQQQtRIsAssAtRE	S258-p
PXN iso3 (human)	tQQQTRIsAssAtRE	S258-p
PXN (mouse)	SQQQTRIsAssAtRE	S258-p
PXN iso2 (mouse)	SQQQTRISASSATRE	S258
PXN (rat)	SQQQTRIsASsATRE	S287-p
PXN (chicken)	SQQQTRIsASsATRE	S259-p
PXN (cow)	SQQQTRIsASSATRE	S252-p

S260-p

QQtRIsAssAtRELD

PXN (human)	QQtRIsAssAtRELD	S260-p
PXN iso2 (human)	QQtRIsAssAtRELD	S260-p
PXN iso3 (human)	QQTRIsAssAtRELD	S260-p
PXN (mouse)	QQTRIsAssAtRELD	S260-p
PXN iso2 (mouse)	QQTRISASSATRELD	S260
PXN (rat)	QQTRIsASsATRELD	S289
PXN (chicken)	QQTRIsASsATRELD	S261
PXN (cow)	QQTRIsASSATRELD	S254

S261-p

QtRIsAssAtRELDE

PXN (human)	QtRIsAssAtRELDE	S261-p
PXN iso2 (human)	QtRIsAssAtRELDE	S261-p
PXN iso3 (human)	QTRIsAssAtRELDE	S261-p
PXN (mouse)	QTRIsAssAtRELDE	S261-p
PXN iso2 (mouse)	QTRISASSATRELDE	S261
PXN (rat)	QTRIsASsATRELDE	S290-p
PXN (chicken)	QTRIsASsATRELDE	S262-p
PXN (cow)	QTRIsASSATRELDE	S255

T263-p

RIsAssAtRELDELM

PXN (human)	RIsAssAtRELDELM	T263-p
PXN iso2 (human)	RIsAssAtRELDELM	T263-p
PXN iso3 (human)	RIsAssAtRELDELM	T263-p
PXN (mouse)	RIsAssAtRELDELM	T263-p
PXN iso2 (mouse)	RISASSATRELDELM	T263
PXN (rat)	RIsASsATRELDELM	T292
PXN (chicken)	RIsASsATRELDELM	T264
PXN (cow)	RIsASSATRELDELM	T257

S272-p

ELDELMAsLsDFkIQ

Upstream

Downstream

Effects on Modified Protein

molecular association, regulation

Effects on Biological Processes:

cell adhesion, induced
cytoskeletal reorganization
transcription, inhibited

Putative in vivo kinases:

PAK2 (human)

Regulatory protein:

FASN (human)
PAK4 (human)
RHOU (human)

Treatment

ischemia
palmitate
staurosporine

PXN (human)	ELDELMAsLsDFkIQ	S272-p
PXN iso2 (human)	ELDELMAsLSDFKFM	S272-p
PXN iso3 (human)	ELDELMASLSDFKGS	S272
PXN (mouse)	ELDELMAsLSDFKMQ	S272-p
PXN iso2 (mouse)	ELDELMASLSDFKFM	S272
PXN (rat)	ELDELMASLSDFKFM	S301
PXN (chicken)	ELDELMAsLsDFKFM	S273-p
PXN (cow)	ELDELMASLSDLSKI	S266

S274-p

DELMAsLsDFkIQGL

Upstream

Downstream

Effects on Modified Protein

molecular association, regulation

Putative in vivo kinases:

PAK2 (human)

PXN (human)	DELMAsLsDFkIQGL	S274-p
PXN iso2 (human)	DELMAsLSDFKFMAQ	S274
PXN iso3 (human)	DELMASLSDFKGSWP	S274
PXN (mouse)	DELMAsLSDFKMQGL	S274
PXN iso2 (mouse)	DELMASLSDFKFMAQ	S274
PXN (rat)	DELMASLSDFKFMAQ	S303
PXN (chicken)	DELMAsLsDFKFMAQ	S275-p
PXN (cow)	DELMASLSDLSKIQD	S268

K277-ub

MAsLsDFkIQGLEQR

PXN (human)	MAsLsDFkIQGLEQR	K277-ub
PXN iso2 (human)	MAsLSDFKFMAQGKt	K277
PXN iso3 (human)	MASLSDFKGSWPLEE	K277
PXN (mouse)	MAsLSDFKMQGLEQR	K277
PXN iso2 (mouse)	MASLSDFKFMAQGKT	K277
PXN (rat)	MASLSDFKFMAQGKT	K306
PXN (chicken)	gap	-
PXN (cow)	ASLSDLSKIQDLEQR	K272

S302-p

WPRDGGRssPGGQDE

PXN (human)	WPRDGGRssPGGQDE	S302-p
PXN iso2 (human)	gap	-
PXN iso3 (human)	gap	-
PXN (mouse)	WPPSSRQSSPEGQDE	S302
PXN iso2 (mouse)	gap	-
PXN (rat)	gap	-
PXN (chicken)	gap	-
PXN (cow)	WPLNGRQSGPEGQDM	S297

S303-p

PRDGGRssPGGQDEG

PXN (human)	PRDGGRssPGGQDEG	S303-p
PXN iso2 (human)	gap	-
PXN iso3 (human)	gap	-
PXN (mouse)	PPSSRQSSPEGQDEG	S303
PXN iso2 (mouse)	gap	-
PXN (rat)	gap	-
PXN (chicken)	gap	-
PXN (cow)	PLNGRQSGPEGQDMG	G298

gap

PXN (human)	gap	-
PXN iso2 (human)	gap	-
PXN iso3 (human)	PCAARHRtPsLRsPD	T311-p
PXN (mouse)	gap	-
PXN iso2 (mouse)	gap	-
PXN (rat)	gap	-
PXN (chicken)	gap	-
PXN (cow)	gap	-

gap

PXN (human)	gap	-
PXN iso2 (human)	gap	-
PXN iso3 (human)	AARHRtPsLRsPDQP	S313-p
PXN (mouse)	gap	-
PXN iso2 (mouse)	gap	-
PXN (rat)	gap	-
PXN (chicken)	gap	-
PXN (cow)	gap	-

gap

PXN (human)	gap	-
PXN iso2 (human)	gap	-
PXN iso3 (human)	HRtPsLRsPDQPPPC	S316-p
PXN (mouse)	gap	-
PXN iso2 (mouse)	gap	-
PXN (rat)	gap	-
PXN (chicken)	gap	-
PXN (cow)	gap	-

T318-p

GFMAQGKtGsSsPPG

PXN (human)	GFMAQGKtGsSsPPG	T318-p
PXN iso2 (human)	KFMAQGKtGsssPPG	T284-p
PXN iso3 (human)	QFMAQGKTGSSsPPG	T332
PXN (mouse)	GFMAQGKtGSssPPG	T318-p
PXN iso2 (mouse)	KFMAQGKTGSSSPPG	T284
PXN (rat)	KFMAQGKTGSSsPPG	T313
PXN (chicken)	KFMAQGKAGGSSsPP	A285
PXN (cow)	GFMAQGKTGSSSPPG	T313

S320-p

MAQGKtGsSsPPGGP

PXN (human)	MAQGKtGsSsPPGGP	S320-p
PXN iso2 (human)	MAQGKtGsssPPGGP	S286-p
PXN iso3 (human)	MAQGKTGSSsPPGGP	S334
PXN (mouse)	MAQGKtGSssPPGGL	S320
PXN iso2 (mouse)	MAQGKTGSSSPPGGL	S286
PXN (rat)	MAQGKTGSSsPPGGL	S315
PXN (chicken)	AQGKAGGSSsPPSTt	S288
PXN (cow)	MAQGKTGSSSPPGGP	S315

S321

AQGKtGsSsPPGGPP

PXN (human)	AQGKtGsSsPPGGPP	S321
PXN iso2 (human)	AQGKtGsssPPGGPP	S287-p
PXN iso3 (human)	AQGKTGSSsPPGGPP	S335
PXN (mouse)	AQGKtGSssPPGGLs	S321-p
PXN iso2 (mouse)	AQGKTGSSSPPGGLS	S287
PXN (rat)	AQGKTGSSsPPGGLS	S316
PXN (chicken)	QGKAGGSSsPPSTtP	S289
PXN (cow)	AQGKTGSSSPPGGPP	S316

S322-p

QGKtGsSsPPGGPPK

Upstream

Treatment

antibody

PXN (human)	QGKtGsSsPPGGPPK	S322-p
PXN iso2 (human)	QGKtGsssPPGGPPK	S288-p
PXN iso3 (human)	QGKTGSSsPPGGPPK	S336-p
PXN (mouse)	QGKtGSssPPGGLsK	S322-p
PXN iso2 (mouse)	QGKTGSSSPPGGLSK	S288
PXN (rat)	QGKTGSSsPPGGLSK	S317-p
PXN (chicken)	GKAGGSSsPPSTtPK	S290-p
PXN (cow)	QGKTGSSSPPGGPPK	S317

P327

sSsPPGGPPKPGsQL

PXN (human)	sSsPPGGPPKPGsQL	P327
PXN iso2 (human)	sssPPGGPPKPGsQL	P293
PXN iso3 (human)	SSsPPGGPPKPGSQL	P341
PXN (mouse)	SssPPGGLsKPGsQL	L327
PXN iso2 (mouse)	SSSPPGGLSKPGSQL	L293
PXN (rat)	SSsPPGGLSKPGsQL	L322
PXN (chicken)	SSsPPSTtPKPGSQL	T295-p
PXN (cow)	SSSPPGGPPKPGSQL	P322

P328

SsPPGGPPKPGsQLD

PXN (human)	SsPPGGPPKPGsQLD	P328
PXN iso2 (human)	ssPPGGPPKPGsQLD	P294
PXN iso3 (human)	SsPPGGPPKPGSQLD	P342
PXN (mouse)	ssPPGGLsKPGsQLD	S328-p
PXN iso2 (mouse)	SSPPGGLSKPGSQLD	S294
PXN (rat)	SsPPGGLSKPGsQLD	S323
PXN (chicken)	SsPPSTtPKPGSQLD	P296
PXN (cow)	SSPPGGPPKPGSQLD	P323

S332-p

GGPPKPGsQLDsMLG

PXN (human)	GGPPKPGsQLDsMLG	S332-p
PXN iso2 (human)	GGPPKPGsQLDsMLG	S298-p
PXN iso3 (human)	GGPPKPGSQLDSMLG	S346
PXN (mouse)	GGLsKPGsQLDsMLG	S332-p
PXN iso2 (mouse)	GGLSKPGSQLDSMLG	S298
PXN (rat)	GGLSKPGsQLDSMLG	S327-p
PXN (chicken)	STtPKPGSQLDTMLG	S300
PXN (cow)	GGPPKPGSQLDSMLG	S327

S336-p

KPGsQLDsMLGsLQS

PXN (human)	KPGsQLDsMLGsLQS	S336-p
PXN iso2 (human)	KPGsQLDsMLGsLQS	S302-p
PXN iso3 (human)	KPGSQLDSMLGSLQS	S350
PXN (mouse)	KPGsQLDsMLGsLQS	S336-p
PXN iso2 (mouse)	KPGSQLDSMLGSLQS	S302
PXN (rat)	KPGsQLDSMLGsLQs	S331
PXN (chicken)	KPGSQLDTMLGsLQS	T304
PXN (cow)	KPGSQLDSMLGSLQS	S331

S340-p

QLDsMLGsLQSDLNK

PXN (human)	QLDsMLGsLQSDLNK	S340-p
PXN iso2 (human)	QLDsMLGsLQSDLNK	S306-p
PXN iso3 (human)	QLDSMLGSLQSDLNK	S354
PXN (mouse)	QLDsMLGsLQSDLNK	S340-p
PXN iso2 (mouse)	QLDSMLGSLQSDLNK	S306
PXN (rat)	QLDSMLGsLQsDLNK	S335-p
PXN (chicken)	QLDTMLGsLQSDLNK	S308-p
PXN (cow)	QLDSMLGSLQSDLNK	S335

S343

sMLGsLQSDLNKLGV

PXN (human)	sMLGsLQSDLNKLGV	S343
PXN iso2 (human)	sMLGsLQSDLNKLGV	S309
PXN iso3 (human)	SMLGSLQSDLNKLGV	S357
PXN (mouse)	sMLGsLQSDLNKLGV	S343
PXN iso2 (mouse)	SMLGSLQSDLNKLGV	S309
PXN (rat)	SMLGsLQsDLNKLGV	S338-p
PXN (chicken)	TMLGsLQSDLNKLGV	S311
PXN (cow)	SMLGSLQSDLNKLGV	S338

K355-ub

LGVATVAkGVCGACK

PXN (human)	LGVATVAkGVCGACK	K355-ub
PXN iso2 (human)	LGVATVAKGVCGACK	K321
PXN iso3 (human)	LGVATVAKGVCGACK	K369
PXN (mouse)	LGVATVAKGVCGACK	K355
PXN iso2 (mouse)	LGVATVAKGVCGACK	K321
PXN (rat)	LGVATVAKGVCGACK	K350
PXN (chicken)	LGVATVAKGVCGACK	K323
PXN (cow)	LGVATVAKGVCGACK	K350

K363

GVCGACKKPIAGQVV

PXN (human)	GVCGACKKPIAGQVV	K363
PXN iso2 (human)	GVCGACKKPIAGQVV	K329
PXN iso3 (human)	GVCGACKKPIAGQVV	K377
PXN (mouse)	GVCGACKkPIAGQVV	K363-ub
PXN iso2 (mouse)	GVCGACKKPIAGQVV	K329
PXN (rat)	GVCGACKKPIAGQVV	K358
PXN (chicken)	GVCGACKKPIAGQVV	K331
PXN (cow)	GVCGACKKPIAGQVV	K358

T371-p

PIAGQVVtAMGKTWH

PXN (human)	PIAGQVVtAMGKTWH	T371-p
PXN iso2 (human)	PIAGQVVTAMGKTWH	T337
PXN iso3 (human)	PIAGQVVTAMGKTWH	T385
PXN (mouse)	PIAGQVVTAMGKTWH	T371
PXN iso2 (mouse)	PIAGQVVTAMGKTWH	T337
PXN (rat)	PIAGQVVTAMGKTWH	T366
PXN (chicken)	PIAGQVVTAMGKtWH	T339
PXN (cow)	PIAGQVVTAMGKTWH	T366

T376

VVtAMGKTWHPEHFV

PXN (human)	VVtAMGKTWHPEHFV	T376
PXN iso2 (human)	VVTAMGKTWHPEHFV	T342
PXN iso3 (human)	VVTAMGKTWHPEHFV	T390
PXN (mouse)	VVTAMGKTWHPEHFV	T376
PXN iso2 (mouse)	VVTAMGKTWHPEHFV	T342
PXN (rat)	VVTAMGKTWHPEHFV	T371
PXN (chicken)	VVTAMGKtWHPEHFV	T344-p
PXN (cow)	VVTAMGKTWHPEHFV	T371

S393

HCQEEIGSRNFFERD

PXN (human)	HCQEEIGSRNFFERD	S393
PXN iso2 (human)	HCQEEIGSRNFFERD	S359
PXN iso3 (human)	HCQEEIGSRNFFERD	S407
PXN (mouse)	HCQEEIGSRNFFERD	S393
PXN iso2 (mouse)	HCQEEIGSRNFFERD	S359
PXN (rat)	HCQEEIGSRNFFERD	S388
PXN (chicken)	HCQEEIGsRNFFERD	S361-p
PXN (cow)	HCQEEIGSRNFFERD	S388

K407

DGQPYCEKDyHNLFs

PXN (human)	DGQPYCEKDyHNLFs	K407
PXN iso2 (human)	DGQPYCEKDyHNLFs	K373
PXN iso3 (human)	DGQPYCEKDYHNLFS	K421
PXN (mouse)	DGQPYCEkDyHSLFS	K407-ub
PXN iso2 (mouse)	DGQPYCEKDYHSLFS	K373
PXN (rat)	DGQPYCEKDYHSLFS	K402
PXN (chicken)	DGQPYCEKDyHNLFs	K375
PXN (cow)	DGQPYCEKDYHNLFS	K402

Y409-p

QPYCEKDyHNLFsPR

PXN (human)	QPYCEKDyHNLFsPR	Y409-p
PXN iso2 (human)	QPYCEKDyHNLFsPR	Y375-p
PXN iso3 (human)	QPYCEKDYHNLFSPR	Y423
PXN (mouse)	QPYCEkDyHSLFSPR	Y409-p
PXN iso2 (mouse)	QPYCEKDYHSLFSPR	Y375
PXN (rat)	QPYCEKDYHSLFSPR	Y404
PXN (chicken)	QPYCEKDyHNLFsPR	Y377-p
PXN (cow)	QPYCEKDYHNLFSPR	Y404

S414-p

KDyHNLFsPRCYYCN

PXN (human)	KDyHNLFsPRCYYCN	S414-p
PXN iso2 (human)	KDyHNLFsPRCYYCN	S380-p
PXN iso3 (human)	KDYHNLFSPRCYYCN	S428
PXN (mouse)	kDyHSLFSPRCYYCN	S414
PXN iso2 (mouse)	KDYHSLFSPRCYYCN	S380
PXN (rat)	KDYHSLFSPRCYYCN	S409
PXN (chicken)	KDyHNLFsPRCYYCN	S382-p
PXN (cow)	KDYHNLFSPRCYYCN	S409

T430

PILDKVVTALDRTWH

PXN (human)	PILDKVVTALDRTWH	T430
PXN iso2 (human)	PILDKVVTALDRTWH	T396
PXN iso3 (human)	PILDKVVTALDRTWH	T444
PXN (mouse)	PILDKVVTALDRTWH	T430
PXN iso2 (mouse)	PILDKVVTALDRTWH	T396
PXN (rat)	PILDKVVTALDRTWH	T425
PXN (chicken)	PILDKVVtALDRtWH	T398-p
PXN (cow)	PILDKVVTALDRTWH	T425

T435

VVTALDRTWHPEHFF

PXN (human)	VVTALDRTWHPEHFF	T435
PXN iso2 (human)	VVTALDRTWHPEHFF	T401
PXN iso3 (human)	VVTALDRTWHPEHFF	T449
PXN (mouse)	VVTALDRTWHPEHFF	T435
PXN iso2 (mouse)	VVTALDRTWHPEHFF	T401
PXN (rat)	VVTALDRTWHPEHFF	T430
PXN (chicken)	VVtALDRtWHPEHFF	T403-p
PXN (cow)	VVTALDRTWHPEHFF	T430

K466

DGKAYCRKDyFDMFA

PXN (human)	DGKAYCRKDyFDMFA	K466
PXN iso2 (human)	DGKAYCRKDyFDMFA	K432
PXN iso3 (human)	DGKAYCRKDYFDMFA	K480
PXN (mouse)	DGKAYCRkDyFDMFA	K466-ub
PXN iso2 (mouse)	DGKAYCRKDYFDMFA	K432
PXN (rat)	DGKAYCRKDYFDMFA	K461
PXN (chicken)	DGKAYCRKDyFDMFA	K434
PXN (cow)	DGKAYCRKDYFDMFA	K461

Y468-p

KAYCRKDyFDMFAPK

PXN (human)	KAYCRKDyFDMFAPK	Y468-p
PXN iso2 (human)	KAYCRKDyFDMFAPK	Y434-p
PXN iso3 (human)	KAYCRKDYFDMFAPK	Y482
PXN (mouse)	KAYCRkDyFDMFAPK	Y468-p
PXN iso2 (mouse)	KAYCRKDYFDMFAPK	Y434
PXN (rat)	KAYCRKDYFDMFAPK	Y463
PXN (chicken)	KAYCRKDyFDMFAPK	Y436-p
PXN (cow)	KAYCRKDYFDMFAPK	Y463

S489

AILENYISALNTLWH

PXN (human)	AILENYISALNTLWH	S489
PXN iso2 (human)	AILENYISALNTLWH	S455
PXN iso3 (human)	AILENYISALNTLWH	S503
PXN (mouse)	AILENYISALNTLWH	S489
PXN iso2 (mouse)	AILENYISALNTLWH	S455
PXN (rat)	AILENYISALNTLWH	S484
PXN (chicken)	AILENYIsALNTLWH	S457-p
PXN (cow)	AILENYISALNTLWH	S484

S513

FTPFVNGSFFEHDGQ

PXN (human)	FTPFVNGSFFEHDGQ	S513
PXN iso2 (human)	FTPFVNGSFFEHDGQ	S479
PXN iso3 (human)	FTPFVNGSFFEHDGQ	S527
PXN (mouse)	FTPFVNGSFFEHDGQ	S513
PXN iso2 (mouse)	FTPFVNGSFFEHDGQ	S479
PXN (rat)	FTPFVNGSFFEHDGQ	S508
PXN (chicken)	FTPFINGsFFEHDGQ	S481-p
PXN (cow)	FTPFVHGSFFEHEGQ	S508

S533-p

HYHERRGsLCSGCQk

PXN (human)	HYHERRGsLCSGCQk	S533-p
PXN iso2 (human)	HYHERRGSLCSGCQk	S499
PXN iso3 (human)	HYHERRGSLCSGCQK	S547
PXN (mouse)	HYHERRGsLCSGCQk	S533-p
PXN iso2 (mouse)	HYHERRGSLCSGCQK	S499
PXN (rat)	HYHERRGSLCSGCQK	S528
PXN (chicken)	HYHERRGsLCsGCQK	S501-p
PXN (cow)	HYHERRGSLCSGCQK	S528

S536

ERRGsLCSGCQkPIT

PXN (human)	ERRGsLCSGCQkPIT	S536
PXN iso2 (human)	ERRGSLCSGCQkPIt	S502
PXN iso3 (human)	ERRGSLCSGCQKPIT	S550
PXN (mouse)	ERRGsLCSGCQkPIT	S536
PXN iso2 (mouse)	ERRGSLCSGCQKPIT	S502
PXN (rat)	ERRGSLCSGCQKPIT	S531
PXN (chicken)	ERRGsLCsGCQKPIT	S504-p
PXN (cow)	ERRGSLCSGCQKPIT	S531

K540-ub

sLCSGCQkPITGRCI

PXN (human)	sLCSGCQkPITGRCI	K540-ub
PXN iso2 (human)	SLCSGCQkPItGRCI	K506-ub
PXN iso3 (human)	SLCSGCQKPITGRCI	K554
PXN (mouse)	sLCSGCQkPITGRCI	K540-ub
PXN iso2 (mouse)	SLCSGCQKPITGRCI	K506
PXN (rat)	SLCSGCQKPITGRCI	K535
PXN (chicken)	sLCsGCQKPITGRCI	K508
PXN (cow)	SLCSGCQKPITGRCI	K535

T543

SGCQkPITGRCITAM

PXN (human)	SGCQkPITGRCITAM	T543
PXN iso2 (human)	SGCQkPItGRCITAM	T509-p
PXN iso3 (human)	SGCQKPITGRCITAM	T557
PXN (mouse)	SGCQkPITGRCITAM	T543
PXN iso2 (mouse)	SGCQKPITGRCITAM	T509
PXN (rat)	SGCQKPITGRCITAM	T538
PXN (chicken)	sGCQKPITGRCITAM	T511
PXN (cow)	SGCQKPITGRCITAM	T538

T572

LKQLNKGTFKEQNDK

PXN (human)	LKQLNKGTFKEQNDK	T572
PXN iso2 (human)	LKQLNKGTFKEQNDK	T538
PXN iso3 (human)	LKQLNKGTFKEQNDK	T586
PXN (mouse)	LKQLNKGtFKEQNDK	T572-p
PXN iso2 (mouse)	LKQLNKGTFKEQNDK	T538
PXN (rat)	LKQLNKGTFKEQNDK	T567
PXN (chicken)	LKQLNKGtFKEQNDK	T540-p
PXN (cow)	LKQLNKGTFKEQNDK	T567