Other Species / Isoforms
  ROMK (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

  HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
S4-p
____MNAsSRNVFDT
Upstream
Downstream
2 0
Effects on Modified Protein
  • activity, induced
  • intracellular localization
Kinase, in vitro:
  • PKCA (human)
ROMK (human) ____MNAsSRNVFDT S4-p
ROMK (mouse) gap -
ROMK (rat) ____MGASERSVFRV S4
ROMK iso2 (rat) gap -
S44-p
RQRARLVsKDGRCNI
Downstream
9 0
Effects on Modified Protein
  • activity, inhibited
  • protein processing
ROMK (human) RQRARLVsKDGRCNI S44-p
ROMK (mouse) RQRARLVsKDGRCNI S25-p
ROMK (rat) RQRARLVsKEGRCNI S44-p
ROMK iso2 (rat) RQRARLVsKEGRCNI S25-p
N117
PEFHPSANHTPCVEN
0 1
ROMK (human) PEFHPSANHTPCVEN N117
ROMK (mouse) PEFYPPDnRTPCVEN N98-ng
ROMK (rat) PEFYPPDNRTPCVEN N117
ROMK iso2 (rat) PEFYPPDNRTPCVEN N98
S183-p
GAILAKIsRPKKRAK
Downstream
2 0
Effects on Modified Protein
  • activity, induced
  • intracellular localization
ROMK (human) GAILAKIsRPKKRAK S183-p
ROMK (mouse) GAILAKISRPKKRAK S164
ROMK (rat) GAILAKISRPKKRAK S183
ROMK iso2 (rat) GAILAKISRPKKRAK S164
T191-p
RPKKRAKtItFSKNA
2 0
ROMK (human) RPKKRAKtItFSKNA T191-p
ROMK (mouse) RPKKRAKTITFSKNA T172
ROMK (rat) RPKKRAKTITFSKNA T191
ROMK iso2 (rat) RPKKRAKTITFSKNA T172
T193-p
KKRAKtItFSKNAVI
Upstream
Downstream
2 0
Effects on Modified Protein
  • activity, inhibited
  • molecular association, regulation
Putative in vivo kinases:
  • PKCA (human)
Treatment
  • GF109203X
  • phorbol_ester
ROMK (human) KKRAKtItFSKNAVI T193-p
ROMK (mouse) KKRAKTITFSKNAVI T174
ROMK (rat) KKRAKTITFSKNAVI T193
ROMK iso2 (rat) KKRAKTITFSKNAVI T174
S201-p
FSKNAVIskRGGKLC
Upstream
Downstream
3 1
Effects on Modified Protein
  • activity, induced
  • intracellular localization
Kinase, in vitro:
  • PKCA (human)
ROMK (human) FSKNAVIskRGGKLC S201-p
ROMK (mouse) FSKNAVIsKRGGKLC S182-p
ROMK (rat) FSKNAVISKRGGKLC S201
ROMK iso2 (rat) FSKNAVISKRGGKLC S182
K202-ac
SKNAVIskRGGKLCL
0 1
ROMK (human) SKNAVIskRGGKLCL K202-ac
ROMK (mouse) SKNAVIsKRGGKLCL K183
ROMK (rat) SKNAVISKRGGKLCL K202
ROMK iso2 (rat) SKNAVISKRGGKLCL K183
S219-p
RVANLRKsLLIGSHI
Upstream
Downstream
5 0
Effects on Modified Protein
  • activity, induced
  • activity, inhibited
  • protein conformation
Treatment
  • Levetiracetam
ROMK (human) RVANLRKsLLIGSHI S219-p
ROMK (mouse) RVANLRKSLLIGSHI S200
ROMK (rat) RVANLRKsLLIGSHI S219-p
ROMK iso2 (rat) RVANLRKsLLIGSHI S200-p
T234-p
YGKLLKTtVTPEGET
1 0
ROMK (human) YGKLLKTtVTPEGET T234-p
ROMK (mouse) YGKLLKTTITPEGET T215
ROMK (rat) YGKLLKTTITPEGET T234
ROMK iso2 (rat) YGKLLKTTITPEGET T215
S313-p
ATCQVRTsYVPEEVL
Upstream
Downstream
5 0
Effects on Modified Protein
  • activity, induced
  • activity, inhibited
  • protein conformation
Treatment
  • Levetiracetam
ROMK (human) ATCQVRTsYVPEEVL S313-p
ROMK (mouse) ATCQVRTSYIPEEVL S294
ROMK (rat) ATCQVRTsYVPEEVL S313-p
ROMK iso2 (rat) ATCQVRTsYVPEEVL S294-p
K331
RFAPIVSKTKEGKyR
0 1
ROMK (human) RFAPIVSKTKEGKyR K331
ROMK (mouse) RFVPIVSkTKEGKYR K312-ub
ROMK (rat) RFVPIVSKTKEGKYR K331
ROMK iso2 (rat) RFVPIVSKTKEGKYR K312
Y337-p
SKTKEGKyRVDFHNF
Upstream
Downstream
4 0
Effects on Modified Protein
  • activity, inhibited
  • intracellular localization
Kinase, in vitro:
  • Src (human)
Putative in vivo kinases:
  • Src (human)
Regulatory protein:
  • Src (human)
Treatment
  • herbimycin_A
  • PAO
ROMK (human) SKTKEGKyRVDFHNF Y337-p
ROMK (mouse) SkTKEGKYRVDFHNF Y318
ROMK (rat) SKTKEGKYRVDFHNF Y337
ROMK iso2 (rat) SKTKEGKYRVDFHNF Y318
K363
AMCLYNEKDVRARMK
0 1
ROMK (human) AMCLYNEKDVRARMK K363
ROMK (mouse) AMCLYNEkDARARMK K344-ub
ROMK (rat) AMCLYNEKDARARMK K363
ROMK iso2 (rat) AMCLYNEKDARARMK K344