Other Species / Isoforms
  ADD2 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

  HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
S2-p
______MsEEtVPEA
0 1
ADD2 (human) ______MsEEtVPEA S2-p
ADD2 iso2 (human) ______MSEETVPEA S2
ADD2 (mouse) ______MSEDTVPEA S2
ADD2 iso2 (mouse) ______MSEDTVPEA S2
ADD2 (rat) ______MsEDTVPEA S2-p
ADD2 iso2 (rat) ______MSEDTVPEA S2
T5-p
___MsEEtVPEAAsP
0 1
ADD2 (human) ___MsEEtVPEAAsP T5-p
ADD2 iso2 (human) ___MSEETVPEAASP T5
ADD2 (mouse) ___MSEDTVPEAAsP T5
ADD2 iso2 (mouse) ___MSEDTVPEAASP T5
ADD2 (rat) ___MsEDTVPEAAsP T5
ADD2 iso2 (rat) ___MSEDTVPEAASP T5
S11-p
EtVPEAAsPPPPQGQ
Upstream
0 14
Treatment
  • dasatinib
ADD2 (human) EtVPEAAsPPPPQGQ S11-p
ADD2 iso2 (human) ETVPEAASPPPPQGQ S11
ADD2 (mouse) DTVPEAAsPPPsQGQ S11-p
ADD2 iso2 (mouse) DTVPEAASPPPSQGQ S11
ADD2 (rat) DTVPEAAsPPPSQGQ S11-p
ADD2 iso2 (rat) DTVPEAASPPPSQGQ S11
P15
EAAsPPPPQGQPYFD
0 1
ADD2 (human) EAAsPPPPQGQPYFD P15
ADD2 iso2 (human) EAASPPPPQGQPYFD P15
ADD2 (mouse) EAAsPPPsQGQHYFD S15-p
ADD2 iso2 (mouse) EAASPPPSQGQHYFD S15
ADD2 (rat) EAAsPPPSQGQHYFD S15
ADD2 iso2 (rat) EAASPPPSQGQHYFD S15
S25
QPYFDRFSEDDPEyM
0 2
ADD2 (human) QPYFDRFSEDDPEyM S25
ADD2 iso2 (human) QPYFDRFSEDDPEYM S25
ADD2 (mouse) QHYFDRFsEDDPEYL S25-p
ADD2 iso2 (mouse) QHYFDRFSEDDPEYL S25
ADD2 (rat) QHYFDRFsEDDPEYL S25-p
ADD2 iso2 (rat) QHYFDRFSEDDPEYL S25
Y31-p
FSEDDPEyMRLRNRA
0 10
ADD2 (human) FSEDDPEyMRLRNRA Y31-p
ADD2 iso2 (human) FSEDDPEYMRLRNRA Y31
ADD2 (mouse) FsEDDPEYLRLRNRA Y31
ADD2 iso2 (mouse) FSEDDPEYLRLRNRA Y31
ADD2 (rat) FsEDDPEYLRLRNRA Y31
ADD2 iso2 (rat) FSEDDPEYLRLRNRA Y31
T55-p
MEQKKRVtMILQsPs
Upstream
1 1
Kinase, in vitro:
  • PKACA (cow)
ADD2 (human) MEQKKRVtMILQsPs T55-p
ADD2 iso2 (human) MEQKKRVTMILQSPS T55
ADD2 (mouse) MEQKKRVTMILQsPs T55
ADD2 iso2 (mouse) MEQKKRVTMILQSPS T55
ADD2 (rat) MEQKKRVTMILQsPS T55
ADD2 iso2 (rat) MEQKKRVTMILQSPS T55
S60-p
RVtMILQsPsFREEL
0 11
ADD2 (human) RVtMILQsPsFREEL S60-p
ADD2 iso2 (human) RVTMILQSPSFREEL S60
ADD2 (mouse) RVTMILQsPsFREEL S60-p
ADD2 iso2 (mouse) RVTMILQSPSFREEL S60
ADD2 (rat) RVTMILQsPSFREEL S60-p
ADD2 iso2 (rat) RVTMILQSPSFREEL S60
S62-p
tMILQsPsFREELEG
0 9
ADD2 (human) tMILQsPsFREELEG S62-p
ADD2 iso2 (human) TMILQSPSFREELEG S62
ADD2 (mouse) TMILQsPsFREELEG S62-p
ADD2 iso2 (mouse) TMILQSPSFREELEG S62
ADD2 (rat) TMILQsPSFREELEG S62
ADD2 iso2 (rat) TMILQSPSFREELEG S62
K77
LIQEQMKKGNNSSNI
0 1
ADD2 (human) LIQEQMKKGNNSSNI K77
ADD2 iso2 (human) LIQEQMKKGNNSSNI K77
ADD2 (mouse) LIQEQMKkGNNsSNI K77-ub
ADD2 iso2 (mouse) LIQEQMKKGNNSSNI K77
ADD2 (rat) LIQEQMKKGNNSSNI K77
ADD2 iso2 (rat) LIQEQMKKGNNSSNI K77
S81
QMKKGNNSSNIWALR
0 1
ADD2 (human) QMKKGNNSSNIWALR S81
ADD2 iso2 (human) QMKKGNNSSNIWALR S81
ADD2 (mouse) QMKkGNNsSNIWALR S81-p
ADD2 iso2 (mouse) QMKKGNNSSNIWALR S81
ADD2 (rat) QMKKGNNSSNIWALR S81
ADD2 iso2 (rat) QMKKGNNSSNIWALR S81
S344
HRPHEVGSVQWAGST
0 1
ADD2 (human) HRPHEVGSVQWAGST S344
ADD2 iso2 (human) HRPHEVGSVQWAGST S344
ADD2 (mouse) HRPHEVGsVQWAGST S344-p
ADD2 iso2 (mouse) HRPHEVGSVQWAGST S344
ADD2 (rat) HRPHEVGSVQWAGST S344
ADD2 iso2 (rat) HRPHEVGSVQWAGST S344
Y377-p
RMLDNLGyRTGYTYR
0 1
ADD2 (human) RMLDNLGyRTGYTYR Y377-p
ADD2 iso2 (human) RMLDNLGYRTGYTYR Y377
ADD2 (mouse) RMLDNLGYRTGYTYR Y377
ADD2 iso2 (mouse) RMLDNLGYRTGYTYR Y377
ADD2 (rat) RMLDNLGYRTGYTYR Y377
ADD2 iso2 (rat) RMLDNLGYRTGYTYR Y377
S396-p
QEKTKHKsEVEIPAT
0 1
ADD2 (human) QEKTKHKsEVEIPAT S396-p
ADD2 iso2 (human) QEKTKHKSEVEIPAT S396
ADD2 (mouse) QEKTKHKSEVEIPAT S396
ADD2 iso2 (mouse) QEKTKHKSEVEIPAT S396
ADD2 (rat) QEKTKHKSEVEIPAT S396
ADD2 iso2 (rat) QEKTKHKSEVEIPAT S396
Y440-p
WLNTPNTyLRVNVAD
0 1
ADD2 (human) WLNTPNTyLRVNVAD Y440-p
ADD2 iso2 (human) WLNTPNTYLRVNVAD Y440
ADD2 (mouse) WLNTPNTYLRVNVAD Y440
ADD2 iso2 (mouse) WLNTPNTYLRVNVAD Y440
ADD2 (rat) WLNTPNTYLRVNVAD Y440
ADD2 iso2 (rat) WLNTPNTYLRVNVAD Y440
S455-p
EVQRSMGsPRPKTTW
0 4
ADD2 (human) EVQRSMGsPRPKTTW S455-p
ADD2 iso2 (human) EVQRSMGSPRPKTTW S455
ADD2 (mouse) EVQRNMGsPRPKTTW S455-p
ADD2 iso2 (mouse) EVQRNMGSPRPKTTW S455
ADD2 (rat) EVQRNMGSPRPKTTW S455
ADD2 iso2 (rat) EVQRNMGSPRPKTTW S455
K464-ac
RPKTTWMkADEVEKS
0 1
ADD2 (human) RPKTTWMkADEVEKS K464-ac
ADD2 iso2 (human) RPKTTWMKADEVEKS K464
ADD2 (mouse) RPKTTWMKADEVEKS K464
ADD2 iso2 (mouse) RPKTTWMKADEVEKS K464
ADD2 (rat) RPKTTWMKADEVEKS K464
ADD2 iso2 (rat) RPKTTWMKADEVEKS K464
S472-p
ADEVEKSsSGMPIRI
0 1
ADD2 (human) ADEVEKSsSGMPIRI S472-p
ADD2 iso2 (human) ADEVEKSSSGMPIRI S472
ADD2 (mouse) ADEVEKSSSGMPIRI S472
ADD2 iso2 (mouse) ADEVEKSSSGMPIRI S472
ADD2 (rat) ADEVEKSSSGMPIRI S472
ADD2 iso2 (rat) ADEVEKSSSGMPIRI S472
Y489-p
PNQFVPLyTDPQEVL
Upstream
Downstream
2 145
Effects on Modified Protein
  • intracellular localization
Putative in vivo kinases:
  • Fyn (human)
Treatment
  • ephrin_B1
ADD2 (human) PNQFVPLyTDPQEVL Y489-p
ADD2 iso2 (human) PNQFVPLYTDPQEVL Y489
ADD2 (mouse) PNQFVPLYTDPQEVL Y489
ADD2 iso2 (mouse) PNQFVPLYTDPQEVL Y489
ADD2 (rat) PNQFVPLyTDPQEVL Y489-p
ADD2 iso2 (rat) PNQFVPLYTDPQEVL Y489
S512-p
QNRQDVKsAGPQSQL
0 2
ADD2 (human) QNRQDVKsAGPQSQL S512-p
ADD2 iso2 (human) QNRQDVKSAGPQSQL S512
ADD2 (mouse) QNRQDIKsAGPQSQL S512-p
ADD2 iso2 (mouse) QNRQDIKSAGPQSQL S512
ADD2 (rat) QNRQDIKSAGPQSQL S512
ADD2 iso2 (rat) QNRQDIKSAGPQSQL S512
S522-p
PQSQLLAsVIAEKsR
0 1
ADD2 (human) PQSQLLAsVIAEKsR S522-p
ADD2 iso2 (human) PQSQLLASVIAEKSR S522
ADD2 (mouse) PQSQLLASVIAEksR S522
ADD2 iso2 (mouse) PQSQLLASVIAEKSR S522
ADD2 (rat) PQSQLLASVIAEKsR S522
ADD2 iso2 (rat) PQSQLLASVIAEKSR S522
K527
LAsVIAEKsRsPstE
0 1
ADD2 (human) LAsVIAEKsRsPstE K527
ADD2 iso2 (human) LASVIAEKSRSPVEQ K527
ADD2 (mouse) LASVIAEksRsPstE K527-ub
ADD2 iso2 (mouse) LASVIAEKSRSPVQQ K527
ADD2 (rat) LASVIAEKsRsPsTE K527
ADD2 iso2 (rat) LASVIAEKSRSPVQQ K527
S528-p
AsVIAEKsRsPstEs
0 5
ADD2 (human) AsVIAEKsRsPstEs S528-p
ADD2 iso2 (human) ASVIAEKSRSPVEQR S528
ADD2 (mouse) ASVIAEksRsPstEs S528-p
ADD2 iso2 (mouse) ASVIAEKSRSPVQQR S528
ADD2 (rat) ASVIAEKsRsPsTES S528-p
ADD2 iso2 (rat) ASVIAEKSRSPVQQR S528
S530-p
VIAEKsRsPstEsQL
0 7
ADD2 (human) VIAEKsRsPstEsQL S530-p
ADD2 iso2 (human) VIAEKSRSPVEQRLP S530
ADD2 (mouse) VIAEksRsPstEsQL S530-p
ADD2 iso2 (mouse) VIAEKSRSPVQQRLP S530
ADD2 (rat) VIAEKsRsPsTESQL S530-p
ADD2 iso2 (rat) VIAEKSRSPVQQRLP S530
-
gap
0 3
ADD2 (human) gap -
ADD2 iso2 (human) VPGAGLQDP______ D558
ADD2 (mouse) gap -
ADD2 iso2 (mouse) PESSGPLtP______ T561-p
ADD2 (rat) gap -
ADD2 iso2 (rat) PESSGPLtP______ T561-p
S532-p
AEKsRsPstEsQLMS
0 64
ADD2 (human) AEKsRsPstEsQLMS S532-p
ADD2 iso2 (human) gap -
ADD2 (mouse) AEksRsPstEsQLMs S532-p
ADD2 iso2 (mouse) gap -
ADD2 (rat) AEKsRsPsTESQLAS S532-p
ADD2 iso2 (rat) gap -
T533-p
EKsRsPstEsQLMSK
0 14
ADD2 (human) EKsRsPstEsQLMSK T533-p
ADD2 iso2 (human) gap -
ADD2 (mouse) EksRsPstEsQLMsK T533-p
ADD2 iso2 (mouse) gap -
ADD2 (rat) EKsRsPsTESQLASK T533
ADD2 iso2 (rat) gap -
S535-p
sRsPstEsQLMSKGD
0 10
ADD2 (human) sRsPstEsQLMSKGD S535-p
ADD2 iso2 (human) gap -
ADD2 (mouse) sRsPstEsQLMsKGD S535-p
ADD2 iso2 (mouse) gap -
ADD2 (rat) sRsPsTESQLASKGD S535
ADD2 iso2 (rat) gap -
S539
stEsQLMSKGDEDTK
0 1
ADD2 (human) stEsQLMSKGDEDTK S539
ADD2 iso2 (human) gap -
ADD2 (mouse) stEsQLMsKGDADTK S539-p
ADD2 iso2 (mouse) gap -
ADD2 (rat) sTESQLASKGDADTK S539
ADD2 iso2 (rat) gap -
S549
DEDTKDDSEETVPNP
0 1
ADD2 (human) DEDTKDDSEETVPNP S549
ADD2 iso2 (human) gap -
ADD2 (mouse) DADTKDEsEETVPNP S549-p
ADD2 iso2 (mouse) gap -
ADD2 (rat) DADTKDELEETVPNP L549
ADD2 iso2 (rat) gap -
K576-ac
KKEVERKkLELDGEk
0 1
ADD2 (human) KKEVERKkLELDGEk K576-ac
ADD2 iso2 (human) gap -
ADD2 (mouse) KKEVERKKLEQEQEG K576
ADD2 iso2 (mouse) gap -
ADD2 (rat) KKEVERKKLEQEQEG K576
ADD2 iso2 (rat) gap -
K583-ac
kLELDGEkEtAPEEP
0 2
ADD2 (human) kLELDGEkEtAPEEP K583-ac
ADD2 iso2 (human) gap -
ADD2 (mouse) EQEQEGEKDIAtEKP K585
ADD2 iso2 (mouse) gap -
ADD2 (rat) EQEQEGEKDAATEEP K585
ADD2 iso2 (rat) gap -
T585-p
ELDGEkEtAPEEPGs
0 1
ADD2 (human) ELDGEkEtAPEEPGs T585-p
ADD2 iso2 (human) gap -
ADD2 (mouse) EQEGEKDIAtEKPGs I587
ADD2 iso2 (mouse) gap -
ADD2 (rat) EQEGEKDAATEEPGs A587
ADD2 iso2 (rat) gap -
P587
DGEkEtAPEEPGsPA
0 1
ADD2 (human) DGEkEtAPEEPGsPA P587
ADD2 iso2 (human) gap -
ADD2 (mouse) EGEKDIAtEKPGsPV T589-p
ADD2 iso2 (mouse) gap -
ADD2 (rat) EGEKDAATEEPGsPV T589
ADD2 iso2 (rat) gap -
S592-p
tAPEEPGsPAksAPA
Upstream
2 33
Kinase, in vitro:
  • ERK2 (human)
Putative in vivo kinases:
  • ERK2 (human)
Treatment
  • U0126
ADD2 (human) tAPEEPGsPAksAPA S592-p
ADD2 iso2 (human) gap -
ADD2 (mouse) IAtEKPGsPVKstPA S594-p
ADD2 iso2 (mouse) gap -
ADD2 (rat) AATEEPGsPVKsTPA S594-p
ADD2 iso2 (rat) gap -
K595-ac
EEPGsPAksAPAsPV
0 1
ADD2 (human) EEPGsPAksAPAsPV K595-ac
ADD2 iso2 (human) gap -
ADD2 (mouse) EKPGsPVKstPAsPV K597
ADD2 iso2 (mouse) gap -
ADD2 (rat) EEPGsPVKsTPAsPV K597
ADD2 iso2 (rat) gap -
S596-p
EPGsPAksAPAsPVQ
Upstream
2 21
Kinase, in vitro:
  • ERK2 (human)
Putative in vivo kinases:
  • ERK2 (human)
Treatment
  • U0126
ADD2 (human) EPGsPAksAPAsPVQ S596-p
ADD2 iso2 (human) gap -
ADD2 (mouse) KPGsPVKstPAsPVQ S598-p
ADD2 iso2 (mouse) gap -
ADD2 (rat) EPGsPVKsTPAsPVQ S598-p
ADD2 iso2 (rat) gap -
A597
PGsPAksAPAsPVQs
0 2
ADD2 (human) PGsPAksAPAsPVQs A597
ADD2 iso2 (human) gap -
ADD2 (mouse) PGsPVKstPAsPVQs T599-p
ADD2 iso2 (mouse) gap -
ADD2 (rat) PGsPVKsTPAsPVQs T599
ADD2 iso2 (rat) gap -
S600-p
PAksAPAsPVQsPAK
Upstream
Downstream
3 28
Effects on Biological Processes:
  • cell growth, induced
  • cytoskeletal reorganization
Kinase, in vitro:
  • ERK2 (human)
Putative in vivo kinases:
  • ERK2 (human)
ADD2 (human) PAksAPAsPVQsPAK S600-p
ADD2 iso2 (human) gap -
ADD2 (mouse) PVKstPAsPVQsPsK S602-p
ADD2 iso2 (mouse) gap -
ADD2 (rat) PVKsTPAsPVQsPTR S602-p
ADD2 iso2 (rat) gap -
S604-p
APAsPVQsPAKEAEt
Upstream
1 14
Putative in vivo kinases:
  • CDK5 (human)
ADD2 (human) APAsPVQsPAKEAEt S604-p
ADD2 iso2 (human) gap -
ADD2 (mouse) tPAsPVQsPsKAGTK S606-p
ADD2 iso2 (mouse) gap -
ADD2 (rat) TPAsPVQsPTRAGTK S606-p
ADD2 iso2 (rat) gap -
A606
AsPVQsPAKEAEtKs
0 1
ADD2 (human) AsPVQsPAKEAEtKs A606
ADD2 iso2 (human) gap -
ADD2 (mouse) AsPVQsPsKAGTKsP S608-p
ADD2 iso2 (mouse) gap -
ADD2 (rat) AsPVQsPTRAGTKsP T608
ADD2 iso2 (rat) gap -
T611-p
sPAKEAEtKsPLVsP
0 1
ADD2 (human) sPAKEAEtKsPLVsP T611-p
ADD2 iso2 (human) gap -
ADD2 (mouse) QsPsKAGTKsPAVsP T612
ADD2 iso2 (mouse) gap -
ADD2 (rat) QsPTRAGTKsPAVsP T612
ADD2 iso2 (rat) gap -
S613-p
AKEAEtKsPLVsPsK
Upstream
Downstream
1 22
Effects on Modified Protein
  • phosphorylation
Effects on Biological Processes:
  • cell growth, induced
  • cytoskeletal reorganization
Putative in vivo kinases:
  • GSK3B (human)
ADD2 (human) AKEAEtKsPLVsPsK S613-p
ADD2 iso2 (human) gap -
ADD2 (mouse) PsKAGTKsPAVsPsK S614-p
ADD2 iso2 (mouse) gap -
ADD2 (rat) PTRAGTKsPAVsPSK S614-p
ADD2 iso2 (rat) gap -
S617-p
EtKsPLVsPsKsLEE
Upstream
1 19
Putative in vivo kinases:
  • CDK5 (human)
ADD2 (human) EtKsPLVsPsKsLEE S617-p
ADD2 iso2 (human) gap -
ADD2 (mouse) GTKsPAVsPsKtsED S618-p
ADD2 iso2 (mouse) gap -
ADD2 (rat) GTKsPAVsPSKAsED S618-p
ADD2 iso2 (rat) gap -
S619-p
KsPLVsPsKsLEEGt
0 8
ADD2 (human) KsPLVsPsKsLEEGt S619-p
ADD2 iso2 (human) gap -
ADD2 (mouse) KsPAVsPsKtsEDTK S620-p
ADD2 iso2 (mouse) gap -
ADD2 (rat) KsPAVsPSKAsEDAK S620
ADD2 iso2 (rat) gap -
S621-p
PLVsPsKsLEEGtKK
0 4
ADD2 (human) PLVsPsKsLEEGtKK S621-p
ADD2 iso2 (human) gap -
ADD2 (mouse) PAVsPsKtsEDTKKT T622-p
ADD2 iso2 (mouse) gap -
ADD2 (rat) PAVsPSKAsEDAKKT A622
ADD2 iso2 (rat) gap -
L622
LVsPsKsLEEGtKKT
0 3
ADD2 (human) LVsPsKsLEEGtKKT L622
ADD2 iso2 (human) gap -
ADD2 (mouse) AVsPsKtsEDTKKTE S623-p
ADD2 iso2 (mouse) gap -
ADD2 (rat) AVsPSKAsEDAKKTE S623-p
ADD2 iso2 (rat) gap -
T626-p
sKsLEEGtKKTEtsK
0 1
ADD2 (human) sKsLEEGtKKTEtsK T626-p
ADD2 iso2 (human) gap -
ADD2 (mouse) PsKtsEDTKKTEVSE T626
ADD2 iso2 (mouse) gap -
ADD2 (rat) PSKAsEDAKKTEVSE A626
ADD2 iso2 (rat) gap -
T631-p
EGtKKTEtsKAATTE
0 1
ADD2 (human) EGtKKTEtsKAATTE T631-p
ADD2 iso2 (human) gap -
ADD2 (mouse) EDTKKTEVSEANTEP V631
ADD2 iso2 (mouse) gap -
ADD2 (rat) EDAKKTEVSEANTEP V631
ADD2 iso2 (rat) gap -
S632-p
GtKKTEtsKAATTEP
0 1
ADD2 (human) GtKKTEtsKAATTEP S632-p
ADD2 iso2 (human) gap -
ADD2 (mouse) DTKKTEVSEANTEPE S632
ADD2 iso2 (mouse) gap -
ADD2 (rat) DAKKTEVSEANTEPE S632
ADD2 iso2 (rat) gap -
T657
NGREEEQTAEEILSK
0 3
ADD2 (human) NGREEEQTAEEILSK T657
ADD2 iso2 (human) gap -
ADD2 (mouse) NGKEEEPsVEEALsK S656-p
ADD2 iso2 (mouse) gap -
ADD2 (rat) NGKEEEPCVEEVLSK C656
ADD2 iso2 (rat) gap -
S663
QTAEEILSKGLSQMT
0 1
ADD2 (human) QTAEEILSKGLSQMT S663
ADD2 iso2 (human) gap -
ADD2 (mouse) PsVEEALsKGLGQMT S662-p
ADD2 iso2 (mouse) gap -
ADD2 (rat) PCVEEVLSKGPGQMT S662
ADD2 iso2 (rat) gap -
T675-p
QMTTSADtDVDTSkD
0 4
ADD2 (human) QMTTSADtDVDTSkD T675-p
ADD2 iso2 (human) gap -
ADD2 (mouse) QMTTNADtDGDsYKD T674-p
ADD2 iso2 (mouse) gap -
ADD2 (rat) QMTTNADtDGDsYKD T674-p
ADD2 iso2 (rat) gap -
T679
SADtDVDTSkDktES
0 3
ADD2 (human) SADtDVDTSkDktES T679
ADD2 iso2 (human) gap -
ADD2 (mouse) NADtDGDsYKDKTES S678-p
ADD2 iso2 (mouse) gap -
ADD2 (rat) NADtDGDsYKDKTEs S678-p
ADD2 iso2 (rat) gap -
K681-ac
DtDVDTSkDktESVT
0 1
ADD2 (human) DtDVDTSkDktESVT K681-ac
ADD2 iso2 (human) gap -
ADD2 (mouse) DtDGDsYKDKTESVt K680
ADD2 iso2 (mouse) gap -
ADD2 (rat) DtDGDsYKDKTEsVT K680
ADD2 iso2 (rat) gap -
K683-ac
DVDTSkDktESVTSG
0 1
ADD2 (human) DVDTSkDktESVTSG K683-ac
ADD2 iso2 (human) gap -
ADD2 (mouse) DGDsYKDKTESVtsG K682
ADD2 iso2 (mouse) gap -
ADD2 (rat) DGDsYKDKTEsVTsG K682
ADD2 iso2 (rat) gap -
T684-p
VDTSkDktESVTSGP
0 1
ADD2 (human) VDTSkDktESVTSGP T684-p
ADD2 iso2 (human) gap -
ADD2 (mouse) GDsYKDKTESVtsGP T683
ADD2 iso2 (mouse) gap -
ADD2 (rat) GDsYKDKTEsVTsGP T683
ADD2 iso2 (rat) gap -
S686
TSkDktESVTSGPMs
0 1
ADD2 (human) TSkDktESVTSGPMs S686
ADD2 iso2 (human) gap -
ADD2 (mouse) sYKDKTESVtsGPLs S685
ADD2 iso2 (mouse) gap -
ADD2 (rat) sYKDKTEsVTsGPLs S685-p
ADD2 iso2 (rat) gap -
T688
kDktESVTSGPMsPE
0 1
ADD2 (human) kDktESVTSGPMsPE T688
ADD2 iso2 (human) gap -
ADD2 (mouse) KDKTESVtsGPLsPE T687-p
ADD2 iso2 (mouse) gap -
ADD2 (rat) KDKTEsVTsGPLsPE T687
ADD2 iso2 (rat) gap -
S689
DktESVTSGPMsPEG
0 2
ADD2 (human) DktESVTSGPMsPEG S689
ADD2 iso2 (human) gap -
ADD2 (mouse) DKTESVtsGPLsPEG S688-p
ADD2 iso2 (mouse) gap -
ADD2 (rat) DKTEsVTsGPLsPEG S688-p
ADD2 iso2 (rat) gap -
S693-p
SVTSGPMsPEGsPsK
Upstream
Downstream
1 15
Effects on Modified Protein
  • phosphorylation
Putative in vivo kinases:
  • GSK3B (human)
ADD2 (human) SVTSGPMsPEGsPsK S693-p
ADD2 iso2 (human) gap -
ADD2 (mouse) SVtsGPLsPEGsPsK S692-p
ADD2 iso2 (mouse) gap -
ADD2 (rat) sVTsGPLsPEGsPSK S692-p
ADD2 iso2 (rat) gap -
S697-p
GPMsPEGsPsKsPsK
Downstream
1 12
Effects on Biological Processes:
  • cell growth, induced
  • cytoskeletal reorganization
ADD2 (human) GPMsPEGsPsKsPsK S697-p
ADD2 iso2 (human) gap -
ADD2 (mouse) GPLsPEGsPsKsPsK S696-p
ADD2 iso2 (mouse) gap -
ADD2 (rat) GPLsPEGsPSKsPSK S696-p
ADD2 iso2 (rat) gap -
S699-p
MsPEGsPsKsPsKKK
0 7
ADD2 (human) MsPEGsPsKsPsKKK S699-p
ADD2 iso2 (human) gap -
ADD2 (mouse) LsPEGsPsKsPsKKK S698-p
ADD2 iso2 (mouse) gap -
ADD2 (rat) LsPEGsPSKsPSKKK S698
ADD2 iso2 (rat) gap -
S701-p
PEGsPsKsPsKKKKK
Upstream
1 10
Putative in vivo kinases:
  • CDK5 (human)
ADD2 (human) PEGsPsKsPsKKKKK S701-p
ADD2 iso2 (human) gap -
ADD2 (mouse) PEGsPsKsPsKKKKK S700-p
ADD2 iso2 (mouse) gap -
ADD2 (rat) PEGsPSKsPSKKKKK S700-p
ADD2 iso2 (rat) gap -
S703-p
GsPsKsPsKKKKKFR
Upstream
1 7
Kinase, in vitro:
  • PKCA (rat)
ADD2 (human) GsPsKsPsKKKKKFR S703-p
ADD2 iso2 (human) gap -
ADD2 (mouse) GsPsKsPsKKKKKFR S702-p
ADD2 iso2 (mouse) gap -
ADD2 (rat) GsPSKsPSKKKKKFR S702
ADD2 iso2 (rat) gap -
T711-p
KKKKKFRtPsFLKKs
Upstream
0 29
Treatment
  • nocodazole
ADD2 (human) KKKKKFRtPsFLKKs T711-p
ADD2 iso2 (human) gap -
ADD2 (mouse) KKKKKFRtPsFLKKS T710-p
ADD2 iso2 (mouse) gap -
ADD2 (rat) KKKKKFRTPsFLKKS T710
ADD2 iso2 (rat) gap -
S713-p
KKKFRtPsFLKKsKK
Upstream
Downstream
7 216
Effects on Modified Protein
  • intracellular localization
  • phosphorylation
  • protein degradation
Effects on Biological Processes:
  • cytoskeletal reorganization
Kinase, in vitro:
  • Chk1 (human)
  • PKACA (cow)
  • PKCA (cow)
  • PKCA (rat)
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Putative in vivo kinases:
  • PKCA (human)
  • PKCZ (human)
Regulatory protein:
  • DARPP-32 (mouse)
  • PPP2CA (mouse)
Treatment
  • 5_6-DCl-cBIMPS
  • angiotensin_2
  • caffeine
  • calyculin_A
  • colforsin
  • nocodazole
  • novel enriched environment
  • peptide inhibitor
  • phorbol_ester
  • pleiotrophin
  • SII_angiotensin_2
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ADD2 (human) KKKFRtPsFLKKsKK S713-p
ADD2 iso2 (human) gap -
ADD2 (mouse) KKKFRtPsFLKKSKK S712-p
ADD2 iso2 (mouse) gap -
ADD2 (rat) KKKFRTPsFLKKSKK S712-p
ADD2 iso2 (rat) gap -
S718-p
tPsFLKKsKKKEKVE
0 3
ADD2 (human) tPsFLKKsKKKEKVE S718-p
ADD2 iso2 (human) gap -
ADD2 (mouse) tPsFLKKSKKKEKVE S717
ADD2 iso2 (mouse) gap -
ADD2 (rat) TPsFLKKSKKKEKVE S717
ADD2 iso2 (rat) gap -
S726-p
KKKEKVEs_______
Upstream
Downstream
2 0
Effects on Modified Protein
  • intracellular localization
  • protein degradation
Effects on Biological Processes:
  • cytoskeletal reorganization
Kinase, in vitro:
  • PKCA (cow)
Putative in vivo kinases:
  • PKCA (human)
Treatment
  • colforsin
  • phorbol_ester
  • pleiotrophin
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ADD2 (human) KKKEKVEs_______ S726-p
ADD2 iso2 (human) gap -
ADD2 (mouse) KKKEKVES_______ S725
ADD2 iso2 (mouse) gap -
ADD2 (rat) KKKEKVEs_______ S725-p
ADD2 iso2 (rat) gap -