Other Species / Isoforms
  MEF2D (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
S98-p
KGFNGCDsPEPDGED
Upstream
Downstream
1 27
Effects on Modified Protein
  • molecular association, regulation
  • ubiquitination
Kinase, in vitro:
  • CDK4 (human)
Treatment
  • taxol
MEF2D (human) KGFNGCDsPEPDGED S98-p
MEF2D iso2 (human) gap -
MEF2D iso4 (human) KGFNGCDSPEPDGED S98
MEF2D (mouse) KGFNGCDsPEPDGED S98-p
MEF2D iso2 (mouse) gap -
MEF2D (rat) KGFNGCDsPEPDGED S98-p
S106-p
PEPDGEDsLEQsPLL
0 18
MEF2D (human) PEPDGEDsLEQsPLL S106-p
MEF2D iso2 (human) gap -
MEF2D iso4 (human) PEPDGEDSLEQSPLL S106
MEF2D (mouse) PEPDGEDsLEQsPLL S106-p
MEF2D iso2 (mouse) gap -
MEF2D (rat) PEPDGEDsLEQSPLL S106-p
S110-p
GEDsLEQsPLLEDKy
Upstream
Downstream
1 12
Effects on Modified Protein
  • molecular association, regulation
  • ubiquitination
Kinase, in vitro:
  • CDK4 (human)
Treatment
  • taxol
MEF2D (human) GEDsLEQsPLLEDKy S110-p
MEF2D iso2 (human) gap -
MEF2D iso4 (human) GEDSLEQSPLLEDKY S110
MEF2D (mouse) GEDsLEQsPLLEDKY S110-p
MEF2D iso2 (mouse) gap -
MEF2D (rat) GEDsLEQSPLLEDKY S110
Y117-p
sPLLEDKyRRAsEEL
0 1
MEF2D (human) sPLLEDKyRRAsEEL Y117-p
MEF2D iso2 (human) gap -
MEF2D iso4 (human) SPLLEDKYRRASEEL Y117
MEF2D (mouse) sPLLEDKYRRAsEEL Y117
MEF2D iso2 (mouse) gap -
MEF2D (rat) SPLLEDKYRRAsEEL Y117
S121-p
EDKyRRAsEELDGLF
Upstream
2 40
Treatment
  • BI2536
  • EGF
  • ischemia
  • MLN8054
  • selumetinib
  • U0126
  • vemurafenib
MEF2D (human) EDKyRRAsEELDGLF S121-p
MEF2D iso2 (human) gap -
MEF2D iso4 (human) EDKYRRASEELDGLF S121
MEF2D (mouse) EDKYRRAsEELDGLF S121-p
MEF2D iso2 (mouse) gap -
MEF2D (rat) EDKYRRAsEELDGLF S121-p
-
gap
0 1
MEF2D (human) gap -
MEF2D iso2 (human) KKHRECESPEVDEVF S97
MEF2D iso4 (human) gap -
MEF2D (mouse) gap -
MEF2D iso2 (mouse) NNDRECEsPEVDEAF S97-p
MEF2D (rat) gap -
-
gap
0 1
MEF2D (human) gap -
MEF2D iso2 (human) VDEVFALTPQTEEKY T107
MEF2D iso4 (human) gap -
MEF2D (mouse) gap -
MEF2D iso2 (mouse) VDEAFALtPQTEEKY T107-p
MEF2D (rat) gap -
T145
PNFAMPVTVPVSNQS
1 0
MEF2D (human) PNFAMPVTVPVSNQS T145
MEF2D iso2 (human) PNFAMPVTVPVSNQS T144
MEF2D iso4 (human) PNFAMPVTVPVSNQS T145
MEF2D (mouse) PNFAMPVTVPVSNQS T145
MEF2D iso2 (mouse) PNFAMPVTVPVSNQS T152
MEF2D (rat) PNFAMPVtVPVsNQS T145-p
S149
MPVTVPVSNQSSLQF
1 0
MEF2D (human) MPVTVPVSNQSSLQF S149
MEF2D iso2 (human) MPVTVPVSNQSSLQF S148
MEF2D iso4 (human) MPVTVPVSNQSSLQF S149
MEF2D (mouse) MPVTVPVSNQSSMQF S149
MEF2D iso2 (mouse) MPVTVPVSNQSSMQF S156
MEF2D (rat) MPVtVPVsNQSsMQF S149-p
S153
VPVSNQSSLQFSNPS
1 0
MEF2D (human) VPVSNQSSLQFSNPS S153
MEF2D iso2 (human) VPVSNQSSLQFSNPS S152
MEF2D iso4 (human) VPVSNQSSLQFSNPS S153
MEF2D (mouse) VPVSNQSSMQFSNPS S153
MEF2D iso2 (mouse) VPVSNQSSMQFSNPS S160
MEF2D (rat) VPVsNQSsMQFSNPS S153-p
S180-p
LTDPRLLsPQQPALQ
Upstream
Downstream
2 53
Effects on Biological Processes:
  • transcription, induced
Treatment
  • 4-HT
  • EGF
  • IgH
  • nocodazole
  • U0126
MEF2D (human) LTDPRLLsPQQPALQ S180-p
MEF2D iso2 (human) LTDPRLLSPQQPALQ S179
MEF2D iso4 (human) LTDPRLLSPQQPALQ S180
MEF2D (mouse) LTDPRLLsPQQPALQ S180-p
MEF2D iso2 (mouse) LTDPRLLSPQQPALQ S187
MEF2D (rat) LTDPRLLsPQQPALQ S180-p
S190
QPALQRNSVsPGLPQ
2 2
MEF2D (human) QPALQRNSVsPGLPQ S190
MEF2D iso2 (human) QPALQRNSVSPGLPQ S189
MEF2D iso4 (human) QPALQRNSVSPGLPQ S190
MEF2D (mouse) QPALQRNsVsPGLPQ S190-p
MEF2D iso2 (mouse) QPALQRNSVSPGLPQ S197
MEF2D (rat) QPALQRNSVSPGLPQ S190
S192-p
ALQRNSVsPGLPQRP
0 8
MEF2D (human) ALQRNSVsPGLPQRP S192-p
MEF2D iso2 (human) ALQRNSVSPGLPQRP S191
MEF2D iso4 (human) ALQRNSVSPGLPQRP S192
MEF2D (mouse) ALQRNsVsPGLPQRP S192-p
MEF2D iso2 (mouse) ALQRNSVSPGLPQRP S199
MEF2D (rat) ALQRNSVSPGLPQRP S192
S201-p
GLPQRPAsAGAMLGG
Upstream
1 7
Regulatory protein:
  • TBK1 (human)
MEF2D (human) GLPQRPAsAGAMLGG S201-p
MEF2D iso2 (human) GLPQRPASAGAMLGG S200
MEF2D iso4 (human) GLPQRPASAGAMLGG S201
MEF2D (mouse) GLPQRPASAGAMLGG S201
MEF2D iso2 (mouse) GLPQRPASAGAMLGG S208
MEF2D (rat) GLPQRPASAGAMLGR S201
S212-p
MLGGDLNsANGACPs
0 2
MEF2D (human) MLGGDLNsANGACPs S212-p
MEF2D iso2 (human) MLGGDLNSANGACPS S211
MEF2D iso4 (human) MLGGDLNSANGACPS S212
MEF2D (mouse) MLGGDLNSANGACPS S212
MEF2D iso2 (mouse) MLGGDLNSANGACPS S219
MEF2D (rat) MLGRDLNSANGACPN S212
S219-p
sANGACPsPVGNGYV
0 4
MEF2D (human) sANGACPsPVGNGYV S219-p
MEF2D iso2 (human) SANGACPSPVGNGYV S218
MEF2D iso4 (human) SANGACPSPVGNGYV S219
MEF2D (mouse) SANGACPSPVGNGYV S219
MEF2D iso2 (mouse) SANGACPSPVGNGYV S226
MEF2D (rat) SANGACPNPVGNGYV N219
S227-p
PVGNGYVsARAsPGL
0 1
MEF2D (human) PVGNGYVsARAsPGL S227-p
MEF2D iso2 (human) PVGNGYVSARASPGL S226
MEF2D iso4 (human) PVGNGYVSARASPGL S227
MEF2D (mouse) PVGNGYVSARAsPGL S227
MEF2D iso2 (mouse) PVGNGYVSARASPGL S234
MEF2D (rat) PVGNGYVSARAsPGL S227
S231-p
GYVsARAsPGLLPVA
Upstream
0 36
Treatment
  • EGF
  • U0126
MEF2D (human) GYVsARAsPGLLPVA S231-p
MEF2D iso2 (human) GYVSARASPGLLPVA S230
MEF2D iso4 (human) GYVSARASPGLLPVA S231
MEF2D (mouse) GYVSARAsPGLLPVA S231-p
MEF2D iso2 (mouse) GYVSARASPGLLPVA S238
MEF2D (rat) GYVSARAsPGLLPVA S231-p
S242-p
LPVANGNsLNkVIPA
0 2
MEF2D (human) LPVANGNsLNkVIPA S242-p
MEF2D iso2 (human) LPVANGNSLNKVIPA S241
MEF2D iso4 (human) LPVANGNSLNKVIPA S242
MEF2D (mouse) LPVANGNSLNKVIPA S242
MEF2D iso2 (mouse) LPVANGNSLNKVIPA S249
MEF2D (rat) LPVANGNGLNKVIPA G242
K245-ac
ANGNsLNkVIPAksP
0 1
MEF2D (human) ANGNsLNkVIPAksP K245-ac
MEF2D iso2 (human) ANGNSLNKVIPAKSP K244
MEF2D iso4 (human) ANGNSLNKVIPAKSP K245
MEF2D (mouse) ANGNSLNKVIPAKsP K245
MEF2D iso2 (mouse) ANGNSLNKVIPAKSP K252
MEF2D (rat) ANGNGLNKVIPAKsP K245
K250-ub
LNkVIPAksPPPPtH
0 1
MEF2D (human) LNkVIPAksPPPPtH K250-ub
MEF2D iso2 (human) LNKVIPAKSPPPPTH K249
MEF2D iso4 (human) LNKVIPAKSPPPPTH K250
MEF2D (mouse) LNKVIPAKsPPPPtH K250
MEF2D iso2 (mouse) LNKVIPAKSPPPPTH K257
MEF2D (rat) LNKVIPAKsPPPPTH K250
S251-p
NkVIPAksPPPPtHS
Upstream
Downstream
1 47
Effects on Modified Protein
  • activity, inhibited
  • intracellular localization
Effects on Biological Processes:
  • transcription, inhibited
Kinase, in vitro:
  • DYRK1A (human)
Putative in vivo kinases:
  • DYRK1A (human)
Treatment
  • harmine
  • siRNA
MEF2D (human) NkVIPAksPPPPtHS S251-p
MEF2D iso2 (human) NKVIPAKSPPPPTHS S250
MEF2D iso4 (human) NKVIPAKSPPPPTHS S251
MEF2D (mouse) NKVIPAKsPPPPtHN S251-p
MEF2D iso2 (mouse) NKVIPAKSPPPPTHN S258
MEF2D (rat) NKVIPAKsPPPPTHN S251-p
T256-p
AksPPPPtHSTQLGA
0 4
MEF2D (human) AksPPPPtHSTQLGA T256-p
MEF2D iso2 (human) AKSPPPPTHSTQLGA T255
MEF2D iso4 (human) AKSPPPPTHSTQLGA T256
MEF2D (mouse) AKsPPPPtHNtQLGA T256-p
MEF2D iso2 (mouse) AKSPPPPTHNTQLGA T263
MEF2D (rat) AKsPPPPTHNTQLGA T256
T259
PPPPtHSTQLGAPSR
0 1
MEF2D (human) PPPPtHSTQLGAPSR T259
MEF2D iso2 (human) PPPPTHSTQLGAPSR T258
MEF2D iso4 (human) PPPPTHSTQLGAPSR T259
MEF2D (mouse) PPPPtHNtQLGAPSR T259-p
MEF2D iso2 (mouse) PPPPTHNTQLGAPSR T266
MEF2D (rat) PPPPTHNTQLGAPSR T259
K267-m2
QLGAPSRkPDLRVIT
Upstream
Downstream
1 1
Effects on Modified Protein
  • molecular association, regulation
Effects on Biological Processes:
  • cell differentiation, inhibited
  • transcription, inhibited
Treatment
  • BIX01294
  • ionomycin
  • pargyline
MEF2D (human) QLGAPSRkPDLRVIT K267-m2
MEF2D iso2 (human) QLGAPSRKPDLRVIT K266
MEF2D iso4 (human) QLGAPSRKPDLRVIT K267
MEF2D (mouse) QLGAPSRKPDLRVIT K267
MEF2D iso2 (mouse) QLGAPSRKPDLRVIT K274
MEF2D (rat) QLGAPSRKPDLRVIT K267
K267-m1
QLGAPSRkPDLRVIT
Upstream
Downstream
1 1
Effects on Modified Protein
  • molecular association, regulation
Effects on Biological Processes:
  • cell differentiation, inhibited
  • transcription, inhibited
Treatment
  • BIX01294
  • ionomycin
  • pargyline
MEF2D (human) QLGAPSRkPDLRVIT K267-m1
MEF2D iso2 (human) QLGAPSRKPDLRVIT K266
MEF2D iso4 (human) QLGAPSRKPDLRVIT K267
MEF2D (mouse) QLGAPSRKPDLRVIT K267
MEF2D iso2 (mouse) QLGAPSRKPDLRVIT K274
MEF2D (rat) QLGAPSRKPDLRVIT K267
S275-gl
PDLRVITsQAGKGLM
0 1
MEF2D (human) PDLRVITsQAGKGLM S275-gl
MEF2D iso2 (human) PDLRVITSQAGKGLM S274
MEF2D iso4 (human) PDLRVITSQAGKGLM S275
MEF2D (mouse) PDLRVITSQGGKGLM S275
MEF2D iso2 (mouse) PDLRVITSQGGKGLM S282
MEF2D (rat) PDLRVITSQGGkGLM S275
K279
VITsQAGKGLMHHLt
0 1
MEF2D (human) VITsQAGKGLMHHLt K279
MEF2D iso2 (human) VITSQAGKGLMHHLT K278
MEF2D iso4 (human) VITSQAGKGLMHHLN K279
MEF2D (mouse) VITSQGGKGLMHHLT K279
MEF2D iso2 (mouse) VITSQGGKGLMHHLN K286
MEF2D (rat) VITSQGGkGLMHHLN K279-ac
T286-p
KGLMHHLtEDHLDLN
0 1
MEF2D (human) KGLMHHLtEDHLDLN T286-p
MEF2D iso2 (human) KGLMHHLTEDHLDLN T285
MEF2D iso4 (human) gap -
MEF2D (mouse) KGLMHHLTEDHLDLN T286
MEF2D iso2 (mouse) gap -
MEF2D (rat) gap -
K439
THPHISIKSEPVsPs
1 0
MEF2D (human) THPHISIKSEPVsPs K439
MEF2D iso2 (human) THPHISIKSEPVSPS K438
MEF2D iso4 (human) THPHISIKSEPVSPS K432
MEF2D (mouse) THPHISIkSEPVsPS K432-ac
MEF2D iso2 (mouse) THPHISIKSEPVSPS K432
MEF2D (rat) THPHISIKSEPVsPS K425
K439-sm
THPHISIkSEPVsPs
1 0
MEF2D (human) THPHISIkSEPVsPs K439-sm
MEF2D iso2 (human) THPHISIKSEPVSPS K438
MEF2D iso4 (human) THPHISIKSEPVSPS K432
MEF2D (mouse) THPHISIKSEPVsPS K432
MEF2D iso2 (mouse) THPHISIKSEPVSPS K432
MEF2D (rat) THPHISIKSEPVsPS K425
S444-p
SIkSEPVsPsRERsP
Upstream
Downstream
6 42
Effects on Modified Protein
  • acetylation
  • activity, inhibited
  • intracellular localization
  • molecular association, regulation
  • sumoylation
Effects on Biological Processes:
  • neural plasticity
  • transcription, inhibited
Putative in vivo kinases:
  • CDK5 (human)
Putative upstream phosphatases:
  • PPP3CA (human)
Regulatory protein:
  • AKAP1 (human)
  • PPP3CA (human)
Treatment
  • ciclosporin
  • seliciclib
MEF2D (human) SIkSEPVsPsRERsP S444-p
MEF2D iso2 (human) SIKSEPVSPSRERSP S443
MEF2D iso4 (human) SIKSEPVSPSRERSP S437
MEF2D (mouse) SIkSEPVsPSRERsP S437-p
MEF2D iso2 (mouse) SIKSEPVSPSRERSP S437
MEF2D (rat) SIKSEPVsPSRERSP S430-p
S446-p
kSEPVsPsRERsPAP
0 18
MEF2D (human) kSEPVsPsRERsPAP S446-p
MEF2D iso2 (human) KSEPVSPSRERSPAP S445
MEF2D iso4 (human) KSEPVSPSRERSPAP S439
MEF2D (mouse) kSEPVsPSRERsPAP S439
MEF2D iso2 (mouse) KSEPVSPSRERSPAP S439
MEF2D (rat) KSEPVsPSRERSPAP S432
S450-p
VsPsRERsPAPPPPA
0 7
MEF2D (human) VsPsRERsPAPPPPA S450-p
MEF2D iso2 (human) VSPSRERSPAPPPPA S449
MEF2D iso4 (human) VSPSRERSPAPPPPA S443
MEF2D (mouse) VsPSRERsPAPPPPA S443-p
MEF2D iso2 (mouse) VSPSRERSPAPPPPA S443
MEF2D (rat) VsPSRERSPAPPPPA S436
S471-p
PEPGDGLssPAGGSY
0 1
MEF2D (human) PEPGDGLssPAGGSY S471-p
MEF2D iso2 (human) PEPGDGLSSPAGGSY S470
MEF2D iso4 (human) PEPGDGLSSPAGGSY S464
MEF2D (mouse) PEPGEGLSSPAGGSY S464
MEF2D iso2 (mouse) PEPGEGLSSPAGGSY S464
MEF2D (rat) PEPGEGLSSPAGGSY S457
S472-p
EPGDGLssPAGGSYE
0 2
MEF2D (human) EPGDGLssPAGGSYE S472-p
MEF2D iso2 (human) EPGDGLSSPAGGSYE S471
MEF2D iso4 (human) EPGDGLSSPAGGSYE S465
MEF2D (mouse) EPGEGLSSPAGGSYE S465
MEF2D iso2 (mouse) EPGEGLSSPAGGSYE S465
MEF2D (rat) EPGEGLSSPAGGSYE S458
S508-p
PEPEAEGsAVkRMRL
0 3
MEF2D (human) PEPEAEGsAVkRMRL S508-p
MEF2D iso2 (human) PEPEAEGSAVKRMRL S507
MEF2D iso4 (human) PEPEAEGSAVKRMRL S501
MEF2D (mouse) PEPEAEGSAVKRMRL S501
MEF2D iso2 (mouse) PEPEAEGSAVKRMRL S501
MEF2D (rat) PEPEAEGSAVkRMRL S494
K511-ac
EAEGsAVkRMRLDtW
0 7
MEF2D (human) EAEGsAVkRMRLDtW K511-ac
MEF2D iso2 (human) EAEGSAVKRMRLDTW K510
MEF2D iso4 (human) EAEGSAVKRMRLDTW K504
MEF2D (mouse) EAEGSAVKRMRLDTW K504
MEF2D iso2 (mouse) EAEGSAVKRMRLDTW K504
MEF2D (rat) EAEGSAVkRMRLDTW K497-ac
T517-p
VkRMRLDtWTLk___
Upstream
0 7
Treatment
  • U0126
MEF2D (human) VkRMRLDtWTLk___ T517-p
MEF2D iso2 (human) VKRMRLDTWTLK___ T516
MEF2D iso4 (human) VKRMRLDTWTLK___ T510
MEF2D (mouse) VKRMRLDTWTLK___ T510
MEF2D iso2 (mouse) VKRMRLDTWTLK___ T510
MEF2D (rat) VkRMRLDTWTLK___ T503
K521-ac
RLDtWTLk_______
0 2
MEF2D (human) RLDtWTLk_______ K521-ac
MEF2D iso2 (human) RLDTWTLK_______ K520
MEF2D iso4 (human) RLDTWTLK_______ K514
MEF2D (mouse) RLDTWTLK_______ K514
MEF2D iso2 (mouse) RLDTWTLK_______ K514
MEF2D (rat) RLDTWTLK_______ K507