Other Species / Isoforms mouse rat

p47phox (human)

LTP

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

HTP

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

Y41-p

DLSEKVVyRRFtEIy

0

2

p47phox (human)	DLSEKVVyRRFtEIy	Y41-p
p47phox (mouse)	DLSEKVVYRKFTEIY	Y41
p47phox (rat)	DLSEKVVYRKFTEIY	Y41

T45-p

KVVyRRFtEIyEFHK

0

1

p47phox (human)	KVVyRRFtEIyEFHK	T45-p
p47phox (mouse)	KVVYRKFTEIYEFHK	T45
p47phox (rat)	KVVYRKFTEIYEFHK	T45

Y48-p

yRRFtEIyEFHKTLK

0

12

p47phox (human)	yRRFtEIyEFHKTLK	Y48-p
p47phox (mouse)	YRKFTEIYEFHKMLK	Y48
p47phox (rat)	YRKFTEIYEFHKMLK	Y48

T133-p

KLPTDNQtKKPEtyL

Upstream

1

1

Kinase, in vitro:

IRAK4 (human)

Putative in vivo kinases:

IRAK4 (human)

Treatment

LPS

p47phox (human)	KLPTDNQtKKPEtyL	T133-p
p47phox (mouse)	KLPTDSQAKKPETYL	A133
p47phox (rat)	KLPNDSQVKKPETYL	V133

T138-p

NQtKKPEtyLMPKDG

Upstream

1

0

Kinase, in vitro:

IRAK4 (human)

p47phox (human)	NQtKKPEtyLMPKDG	T138-p
p47phox (mouse)	SQAKKPETYLVPKDG	T138
p47phox (rat)	SQVKKPETYLTAKDG	T138

Y139-p

QtKKPEtyLMPKDGK

0

1

p47phox (human)	QtKKPEtyLMPKDGK	Y139-p
p47phox (mouse)	QAKKPETYLVPKDGK	Y139
p47phox (rat)	QVKKPETYLTAKDGK	Y139

T153-p

KSTATDItGPIILQT

Upstream

1

0

Kinase, in vitro:

IRAK4 (human)

p47phox (human)	KSTATDItGPIILQT	T153-p
p47phox (mouse)	KNNVADITGPIILQT	T153
p47phox (rat)	KNNVADITGPIILQT	T153

S208-p

KRGWIPAsFLEPLDS

Upstream

2

0

Kinase, in vitro:

CK2A1 (human)

p47phox (human)	KRGWIPAsFLEPLDS	S208-p
p47phox (mouse)	KRGWVPAsYLEPLDS	S208-p
p47phox (rat)	KRGWVPASYLEPLDS	S208

Y279-p

TGYFPSMyLQKsGQD

1

0

p47phox (human)	TGYFPSMyLQKsGQD	Y279-p
p47phox (mouse)	TGYFPSMYLQKAGEE	Y279
p47phox (rat)	TGYFPSMYLQKAGEE	Y279

S283-p

PSMyLQKsGQDVsQA

Upstream

1

0

Kinase, in vitro:

CK2A1 (human)

p47phox (human)	PSMyLQKsGQDVsQA	S283-p
p47phox (mouse)	PSMYLQKAGEEITQA	A283
p47phox (rat)	PSMYLQKAGEEITQA	A283

S288-p

QKsGQDVsQAQRQIK

Upstream

1

1

Kinase, in vitro:

IRAK4 (human)

Putative in vivo kinases:

IRAK4 (human)

Treatment

LPS

p47phox (human)	QKsGQDVsQAQRQIK	S288-p
p47phox (mouse)	QKAGEEITQAQRQIR	T288
p47phox (rat)	QKAGEEITQAQRQIR	T288

S303-p

RGAPPRRssIRNAHs

Upstream

Downstream

9

0

Effects on Modified Protein

activity, induced
enzymatic activity, induced
molecular association, regulation

Kinase, in vitro:

PKCA (human)
PKCB iso2 (human)
PKCD (human)

Treatment

CL097
fMLP
phorbol_ester

p47phox (human)	RGAPPRRssIRNAHs	S303-p
p47phox (mouse)	RGAPPRRsTIRNAQS	S304-p
p47phox (rat)	RGAPPRRsTIRNAQS	S304-p

S304-p

GAPPRRssIRNAHsI

Upstream

Downstream

17

0

Effects on Modified Protein

activity, induced
enzymatic activity, induced
intracellular localization
molecular association, regulation

Effects on Biological Processes:

cell growth, induced
signaling pathway regulation

Kinase, in vitro:

Akt1 (human)
PKCA (human)
PKCB (human)
PKCB iso2 (human)
PKCD (human)
PKCZ (human)
ROCK2 (human)

Putative in vivo kinases:

Akt3 (human)
PKCD (human)
PKCZ (human)
ROCK2 (human)

Regulatory protein:

ANGPT1 (human)
FPR1 (mouse)
p67phox (human)

Treatment

calphostin_C
catalase
CL097
DPI
fMLP
KD025
LPS
pansorbin
phorbol_ester
PKC-zeta_inhibitor
rottlerin
SOD
thymoquinone
Y27632
zymosan

p47phox (human)	GAPPRRssIRNAHsI	S304-p
p47phox (mouse)	GAPPRRsTIRNAQSI	T305
p47phox (rat)	GAPPRRsTIRNAQSI	T305

S310-p

ssIRNAHsIHQRsRK

2

0

p47phox (human)	ssIRNAHsIHQRsRK	S310-p
p47phox (mouse)	sTIRNAQSIHQRsRK	S311
p47phox (rat)	sTIRNAQSIHQRsRK	S311

S315-p

AHsIHQRsRKRLsQD

Upstream

Downstream

14

0

Effects on Modified Protein

enzymatic activity, induced
molecular association, regulation

Effects on Biological Processes:

signaling pathway regulation

Kinase, in vitro:

PKCA (human)
PKCB (human)
PKCB iso2 (human)
PKCD (human)
PKCZ (human)
ROCK2 (human)

Putative in vivo kinases:

ROCK2 (human)

Regulatory protein:

p67phox (human)

Treatment

catalase
CL097
DPI
fMLP
juglone
KD025
LPS
pansorbin
phorbol_ester
SOD
TNF
Y27632
zymosan

p47phox (human)	AHsIHQRsRKRLsQD	S315-p
p47phox (mouse)	AQSIHQRsRKRLsQD	S316-p
p47phox (rat)	AQSIHQRsRKRLsQD	S316-p

S320-p

QRsRKRLsQDAYRRN

Upstream

Downstream

13

18

Effects on Modified Protein

enzymatic activity, induced
molecular association, regulation

Effects on Biological Processes:

signaling pathway regulation

Kinase, in vitro:

IRAK4 (human)
PKACA (human)
PKCA (human)
PKCB (human)
PKCB iso2 (human)
PKCD (human)
PKCZ (human)
ROCK2 (human)

Putative in vivo kinases:

IRAK4 (human)
ROCK2 (human)

Regulatory protein:

p67phox (human)

Treatment

catalase
CL097
DPI
fMLP
KD025
LPS
pansorbin
phorbol_ester
SOD
Y27632
zymosan

p47phox (human)	QRsRKRLsQDAYRRN	S320-p
p47phox (mouse)	QRsRKRLsQDtYRRN	S321-p
p47phox (rat)	QRsRKRLsQDTYRRN	S321-p

A323

RKRLsQDAYRRNsVR

0

2

p47phox (human)	RKRLsQDAYRRNsVR	A323
p47phox (mouse)	RKRLsQDtYRRNsVR	T324-p
p47phox (rat)	RKRLsQDTYRRNSVR	T324

S328-p

QDAYRRNsVRFLQQR

Upstream

Downstream

22

0

Effects on Modified Protein

enzymatic activity, induced
intracellular localization
molecular association, regulation
phosphorylation

Effects on Biological Processes:

cell growth, induced
signaling pathway regulation

Kinase, in vitro:

Akt1 (human)
PKACA (human)
PKCA (human)
PKCB (human)
PKCB iso2 (human)
PKCD (human)
PKCZ (human)
ROCK2 (human)

Putative in vivo kinases:

Akt3 (human)
ROCK2 (human)

Regulatory protein:

FPR1 (mouse)
p67phox (human)

Treatment

albumin
anv-polysaccharides
catalase
CL097
DPI
eugenol
fibrinogen
fMLP
GM-CSF
juglone
KD025
LPS
LY294002
pansorbin
phorbol_ester
SOD
thymoquinone
TNF
Y27632
zymosan

p47phox (human)	QDAYRRNsVRFLQQR	S328-p
p47phox (mouse)	QDtYRRNsVRFLQQR	S329-p
p47phox (rat)	QDTYRRNSVRFLQQR	S329

S345-p

QARPGPQsPGsPLEE

Upstream

Downstream

24

7

Effects on Modified Protein

activity, induced
enzymatic activity, induced
intracellular localization
molecular association, regulation
phosphorylation

Effects on Biological Processes:

cell growth, induced
signaling pathway regulation

Kinase, in vitro:

ERK1 (human)
IRAK4 (human)
P38A (human)
ROCK2 (human)

Putative in vivo kinases:

ERK1 (human)
ERK2 (human)
IRAK4 (human)
P38A (human)
ROCK2 (human)

Regulatory protein:

p67phox (human)
RHOA (human)

Treatment

alpha-Iso-cubebene
antibody
apocynin
CL097
DPI
eugenol
fMLP
genistein
GM-CSF
HMGB1
juglone
LPS
NAC
pansorbin
PD98059
peptide inhibitor
phorbol_ester
PP2
SB203580
Tat
TNF
U0126
Wnt3a
Y27632
zymosan

p47phox (human)	QARPGPQsPGsPLEE	S345-p
p47phox (mouse)	PGRPGPLsTDGTKDN	S346-p
p47phox (rat)	PARPGPQsPDSKDNP	S346-p

S348-p

PGPQsPGsPLEEERQ

Upstream

Downstream

9

7

Effects on Modified Protein

enzymatic activity, induced
intracellular localization

Effects on Biological Processes:

carcinogenesis, induced
cell growth, induced

Kinase, in vitro:

CK2A1 (human)
ERK1 (human)
IRAK4 (human)
P38A (human)
PKCD (human)

Putative in vivo kinases:

PKCD (human)

Treatment

fMLP
phorbol_ester

p47phox (human)	PGPQsPGsPLEEERQ	S348-p
p47phox (mouse)	PGPLsTDGTKDNPST	G349
p47phox (rat)	PGPQsPDSKDNPSTP	S349

T356-p

PLEEERQtQRsKPQP

Upstream

1

1

Kinase, in vitro:

IRAK4 (human)

Putative in vivo kinases:

IRAK4 (human)

Treatment

LPS

p47phox (human)	PLEEERQtQRsKPQP	T356-p
p47phox (mouse)	GTKDNPSTPRVKPQP	T356
p47phox (rat)	DSKDNPSTPRAKPQP	T355

S359-p

EERQtQRsKPQPAVP

Upstream

Downstream

12

0

Effects on Modified Protein

activity, induced
enzymatic activity, induced
intracellular localization
molecular association, regulation
phosphorylation

Kinase, in vitro:

IRAK4 (human)
PKACA (human)
PKCA (human)
PKCA (rat)
PKCB iso2 (human)
PKCD (human)

Treatment

alpha-Iso-cubebene
HMGB1

p47phox (human)	EERQtQRsKPQPAVP	S359-p
p47phox (mouse)	DNPSTPRVKPQPAVP	V359
p47phox (rat)	DNPSTPRAKPQPAVP	A358

S370-p

PAVPPRPsADLILNR

Upstream

Downstream

11

0

Effects on Modified Protein

activity, induced
enzymatic activity, induced
intracellular localization
molecular association, regulation
phosphorylation

Effects on Biological Processes:

signaling pathway regulation

Kinase, in vitro:

IRAK4 (human)
PKACA (human)
PKCA (human)
PKCA (rat)
PKCB iso2 (human)
PKCD (human)

Treatment

alpha-Iso-cubebene
HMGB1

p47phox (human)	PAVPPRPsADLILNR	S370-p
p47phox (mouse)	PAVPPRPSSDLILHR	S370
p47phox (rat)	PAVPPRPSSDLILHR	S369

S379-p

DLILNRCsEstKRKL

Upstream

Downstream

9

1

Effects on Modified Protein

enzymatic activity, induced
intracellular localization
molecular association, regulation
phosphorylation
protein conformation

Effects on Biological Processes:

carcinogenesis, induced
cell growth, induced
signaling pathway regulation

Kinase, in vitro:

PKCA (human)
PKCB iso2 (human)
PKCD (human)

Putative in vivo kinases:

PKCD (human)

Treatment

phorbol_ester

p47phox (human)	DLILNRCsEstKRKL	S379-p
p47phox (mouse)	DLILHRCTESTKRKL	T379
p47phox (rat)	DLILHRCTESTKRKL	T378

S381-p

ILNRCsEstKRKLAS

0

1

p47phox (human)	ILNRCsEstKRKLAS	S381-p
p47phox (mouse)	ILHRCTESTKRKLTS	S381
p47phox (rat)	ILHRCTESTKRKLTS	S380

T382-p

LNRCsEstKRKLASA

0

1

p47phox (human)	LNRCsEstKRKLASA	T382-p
p47phox (mouse)	LHRCTESTKRKLTSA	T382
p47phox (rat)	LHRCTESTKRKLTSA	T381