Other Species / Isoforms
  MRE11A (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
-
gap
0 10
MRE11A (human) gap -
MRE11A iso2 (human) gap -
MRE11A iso3 (human) gap -
MRE11A (mouse) ______MsPtDPLDD S2-p
MRE11A (rat) ______MSPTDPLDD S2
-
gap
0 1
MRE11A (human) gap -
MRE11A iso2 (human) gap -
MRE11A iso3 (human) gap -
MRE11A (mouse) ____MsPtDPLDDED T4-p
MRE11A (rat) ____MSPTDPLDDED T4
T12-p
DALDDENtFKILVAT
0 1
MRE11A (human) DALDDENtFKILVAT T12-p
MRE11A iso2 (human) DALDDENTFKILVAT T12
MRE11A iso3 (human) QKGDDENTFKILVAT T15
MRE11A (mouse) DPLDDEDTFKILVAT T12
MRE11A (rat) DPLDDEDTFKILVAT T12
K70-ub
HENKPSRkTLHtCLE
0 1
MRE11A (human) HENKPSRkTLHtCLE K70-ub
MRE11A iso2 (human) HENKPSRKTLHTCLE K70
MRE11A iso3 (human) HENKPSRKTLHTCLE K73
MRE11A (mouse) HENKPSRKTLHSCLE K70
MRE11A (rat) HENKPSRKTLHSCLE K70
T74-p
PSRkTLHtCLELLRK
0 1
MRE11A (human) PSRkTLHtCLELLRK T74-p
MRE11A iso2 (human) PSRKTLHTCLELLRK T74
MRE11A iso3 (human) PSRKTLHTCLELLRK T77
MRE11A (mouse) PSRKTLHSCLELLRK S74
MRE11A (rat) PSRKTLHSCLELLRK S74
S158-p
NHFGRSMsVEkIDIs
0 1
MRE11A (human) NHFGRSMsVEkIDIs S158-p
MRE11A iso2 (human) NHFGRSMSVEKIDIS S158
MRE11A iso3 (human) NHFGRSMSVEKIDIS S161
MRE11A (mouse) NHFGRSMSVEKVDIS S158
MRE11A (rat) NHFGRSMSVEKVDIS S158
K161-ub
GRSMsVEkIDIsPVL
0 1
MRE11A (human) GRSMsVEkIDIsPVL K161-ub
MRE11A iso2 (human) GRSMSVEKIDISPVL K161
MRE11A iso3 (human) GRSMSVEKIDISPVL K164
MRE11A (mouse) GRSMSVEKVDISPVL K161
MRE11A (rat) GRSMSVEKVDISPVL K161
S165-p
sVEkIDIsPVLLQkG
0 2
MRE11A (human) sVEkIDIsPVLLQkG S165-p
MRE11A iso2 (human) SVEKIDISPVLLQKG S165
MRE11A iso3 (human) SVEKIDISPVLLQKG S168
MRE11A (mouse) SVEKVDISPVLLQKG S165
MRE11A (rat) SVEKVDISPVLLQKG S165
K171-ub
IsPVLLQkGSTKIAL
0 1
MRE11A (human) IsPVLLQkGSTKIAL K171-ub
MRE11A iso2 (human) ISPVLLQKGSTKIAL K171
MRE11A iso3 (human) ISPVLLQKGSTKIAL K174
MRE11A (mouse) ISPVLLQKGSTKLAL K171
MRE11A (rat) ISPVLLQKGSTKLAL K171
S183-p
IALYGLGsIPDERLy
0 1
MRE11A (human) IALYGLGsIPDERLy S183-p
MRE11A iso2 (human) IALYGLGSIPDERLY S183
MRE11A iso3 (human) IALYGLGSIPDERLY S186
MRE11A (mouse) LALYGLGSIPDERLY S183
MRE11A (rat) LALYGLGSIPDERLY S183
Y190-p
sIPDERLyRMFVNkk
0 1
MRE11A (human) sIPDERLyRMFVNkk Y190-p
MRE11A iso2 (human) SIPDERLYRMFVNKK Y190
MRE11A iso3 (human) SIPDERLYRMFVNKK Y193
MRE11A (mouse) SIPDERLYRMFVNkk Y190
MRE11A (rat) SIPDERLYRMFVNKK Y190
K196-ac
LyRMFVNkkVTMLRP
0 8
MRE11A (human) LyRMFVNkkVTMLRP K196-ac
MRE11A iso2 (human) LYRMFVNKKVTMLRP K196
MRE11A iso3 (human) LYRMFVNKKVTMLRP K199
MRE11A (mouse) LYRMFVNkkVTMLRP K196-ac
MRE11A (rat) LYRMFVNKKVTMLRP K196
K197-ac
yRMFVNkkVTMLRPK
0 8
MRE11A (human) yRMFVNkkVTMLRPK K197-ac
MRE11A iso2 (human) YRMFVNKKVTMLRPK K197
MRE11A iso3 (human) YRMFVNKKVTMLRPK K200
MRE11A (mouse) YRMFVNkkVTMLRPK K197-ac
MRE11A (rat) YRMFVNKKVTMLRPK K197
K197-ub
yRMFVNkkVTMLRPK
0 1
MRE11A (human) yRMFVNkkVTMLRPK K197-ub
MRE11A iso2 (human) YRMFVNKKVTMLRPK K197
MRE11A iso3 (human) YRMFVNKKVTMLRPK K200
MRE11A (mouse) YRMFVNkKVTMLRPK K197
MRE11A (rat) YRMFVNKKVTMLRPK K197
K255-ub
ECKIAPTkNEQQLFY
0 2
MRE11A (human) ECKIAPTkNEQQLFY K255-ub
MRE11A iso2 (human) ECKIAPTKNEQQLFY K255
MRE11A iso3 (human) ECKIAPTKNEQQLFY K258
MRE11A (mouse) ECKIGPIKNEQQLFY K255
MRE11A (rat) ECKIGPTRNEQQLFY R255
K255-sm
ECKIAPTkNEQQLFY
0 1
MRE11A (human) ECKIAPTkNEQQLFY K255-sm
MRE11A iso2 (human) ECKIAPTKNEQQLFY K255
MRE11A iso3 (human) ECKIAPTKNEQQLFY K258
MRE11A (mouse) ECKIGPIKNEQQLFY K255
MRE11A (rat) ECKIGPTRNEQQLFY R255
S264-p
EQQLFYIsQPGSSVV
Upstream
Downstream
2 0
Effects on Modified Protein
  • molecular association, regulation
Kinase, in vitro:
  • ATM (human)
Treatment
  • caffeine
  • DSBs
  • KU-55933
  • NU7026
  • okadaic_acid
MRE11A (human) EQQLFYIsQPGSSVV S264-p
MRE11A iso2 (human) EQQLFYISQPGSSVV S264
MRE11A iso3 (human) EQQLFYISQPGSSVV S267
MRE11A (mouse) EQQLFYVSQPGSSVV S264
MRE11A (rat) EQQLFYVSQPGSSVV S264
T272-p
QPGSSVVtsLsPGEA
0 1
MRE11A (human) QPGSSVVtsLsPGEA T272-p
MRE11A iso2 (human) QPGSSVVTSLSPGEA T272
MRE11A iso3 (human) QPGSSVVTSLSPGEA T275
MRE11A (mouse) QPGSSVVTSLSPGEA T272
MRE11A (rat) QPGSSVVTALSPGET T272
S273-p
PGSSVVtsLsPGEAV
0 1
MRE11A (human) PGSSVVtsLsPGEAV S273-p
MRE11A iso2 (human) PGSSVVTSLSPGEAV S273
MRE11A iso3 (human) PGSSVVTSLSPGEAV S276
MRE11A (mouse) PGSSVVTSLSPGEAV S273
MRE11A (rat) PGSSVVTALSPGETV A273
S275-p
SSVVtsLsPGEAVKk
0 4
MRE11A (human) SSVVtsLsPGEAVKk S275-p
MRE11A iso2 (human) SSVVTSLSPGEAVKK S275
MRE11A iso3 (human) SSVVTSLSPGEAVKK S278
MRE11A (mouse) SSVVTSLSPGEAVKK S275
MRE11A (rat) SSVVTALSPGETVKK S275
K282-ub
sPGEAVKkHVGLLRI
0 1
MRE11A (human) sPGEAVKkHVGLLRI K282-ub
MRE11A iso2 (human) SPGEAVKKHVGLLRI K282
MRE11A iso3 (human) SPGEAVKKHVGLLRI K285
MRE11A (mouse) SPGEAVKKHVGLLRI K282
MRE11A (rat) SPGETVKKHVGLLRV K282
K298-ub
GRKMNMHkIPLHTVR
0 1
MRE11A (human) GRKMNMHkIPLHTVR K298-ub
MRE11A iso2 (human) GRKMNMHKIPLHTVR K298
MRE11A iso3 (human) GRKMNMHKIPLHTVR K301
MRE11A (mouse) GRKMNMQKLPLRTVR K298
MRE11A (rat) GRKMNMQKLPLRTVR K298
T329-p
NPDNPKVtQAIQSFC
Upstream
Downstream
1 0
Effects on Modified Protein
  • molecular association, regulation
Treatment
  • caffeine
  • DSBs
  • KU-55933
  • NU7026
  • okadaic_acid
MRE11A (human) NPDNPKVtQAIQSFC T329-p
MRE11A iso2 (human) NPDNPKVTQAIQSFC T329
MRE11A iso3 (human) NPDNPKVTQAIQSFC T332
MRE11A (mouse) NPDNPKVTQAIQSFC T329
MRE11A (rat) NPDNPKVTQAIQSFC T329
K339-ub
IQSFCLEkIEEMLEN
0 1
MRE11A (human) IQSFCLEkIEEMLEN K339-ub
MRE11A iso2 (human) IQSFCLEKIEEMLEN K339
MRE11A iso3 (human) IQSFCLEKIEEMLEN K342
MRE11A (mouse) IQSFCLEKIEEMLDS K339
MRE11A (rat) IQSFCLEKIEEMLDS K339
K360-ub
GNSHQPEkPLVRLRV
0 2
MRE11A (human) GNSHQPEkPLVRLRV K360-ub
MRE11A iso2 (human) GNSHQPEKPLVRLRV K360
MRE11A iso3 (human) GNSHQPEKPLVRLRV K363
MRE11A (mouse) GNPQQPGKPLIRLRV K360
MRE11A (rat) GNPQQPEKPLIRLRV K360
S382-p
PFSVLRFsQkFVDrV
Upstream
Downstream
1 0
Effects on Modified Protein
  • molecular association, regulation
Treatment
  • caffeine
  • DSBs
  • KU-55933
  • NU7026
  • okadaic_acid
MRE11A (human) PFSVLRFsQkFVDrV S382-p
MRE11A iso2 (human) PFSVLRFSQKFVDRV S382
MRE11A iso3 (human) PFSVLRFSQKFVDRV S385
MRE11A (mouse) PFNVLRFSQKFVDRV S382
MRE11A (rat) PFNVLRFSQKFVDRV S382
K384-ub
SVLRFsQkFVDrVAN
0 4
MRE11A (human) SVLRFsQkFVDrVAN K384-ub
MRE11A iso2 (human) SVLRFSQKFVDRVAN K384
MRE11A iso3 (human) SVLRFSQKFVDRVAN K387
MRE11A (mouse) NVLRFSQKFVDRVAN K384
MRE11A (rat) NVLRFSQKFVDRVAN K384
R388-m1
FsQkFVDrVANPkDI
0 1
MRE11A (human) FsQkFVDrVANPkDI R388-m1
MRE11A iso2 (human) FSQKFVDRVANPKDI R388
MRE11A iso3 (human) FSQKFVDRVANPKDI R391
MRE11A (mouse) FSQKFVDRVANPKDV R388
MRE11A (rat) FSQKFVDRVANPKDV R388
K393-ub
VDrVANPkDIIHFFR
Upstream
0 5
Treatment
  • MG132
MRE11A (human) VDrVANPkDIIHFFR K393-ub
MRE11A iso2 (human) VDRVANPKDIIHFFR K393
MRE11A iso3 (human) VDRVANPKDIIHFFR K396
MRE11A (mouse) VDRVANPKDVIHFFR K393
MRE11A (rat) VDRVANPKDVIHFFR K393
K407-ub
RHREQKEkTGEEINF
0 2
MRE11A (human) RHREQKEkTGEEINF K407-ub
MRE11A iso2 (human) RHREQKEKTGEEINF K407
MRE11A iso3 (human) RHREQKEKTGEEINF K410
MRE11A (mouse) RHREQKGKTGEEINF K407
MRE11A (rat) RHREQKGKTGEEINF K407
K416-ac
GEEINFGkLITkPSE
0 2
MRE11A (human) GEEINFGkLITkPSE K416-ac
MRE11A iso2 (human) GEEINFGKLITKPSE K416
MRE11A iso3 (human) GEEINFGKLITKPSE K419
MRE11A (mouse) GEEINFGMLITKPAS M416
MRE11A (rat) GEEINFGKLIIKPAS K416
K416-ub
GEEINFGkLITkPSE
0 3
MRE11A (human) GEEINFGkLITkPSE K416-ub
MRE11A iso2 (human) GEEINFGKLITKPSE K416
MRE11A iso3 (human) GEEINFGKLITKPSE K419
MRE11A (mouse) GEEINFGMLITKPAS M416
MRE11A (rat) GEEINFGKLIIKPAS K416
K416-sm
GEEINFGkLITkPSE
0 1
MRE11A (human) GEEINFGkLITkPSE K416-sm
MRE11A iso2 (human) GEEINFGKLITKPSE K416
MRE11A iso3 (human) GEEINFGKLITKPSE K419
MRE11A (mouse) GEEINFGMLITKPAS M416
MRE11A (rat) GEEINFGKLIIKPAS K416
K420-ub
NFGkLITkPSEGTtL
0 3
MRE11A (human) NFGkLITkPSEGTtL K420-ub
MRE11A iso2 (human) NFGKLITKPSEGTTL K420
MRE11A iso3 (human) NFGKLITKPSEGTTL K423
MRE11A (mouse) NFGMLITKPASEGAT K420
MRE11A (rat) NFGKLIIKPASEGTT K420
T426-p
TkPSEGTtLRVEDLV
0 1
MRE11A (human) TkPSEGTtLRVEDLV T426-p
MRE11A iso2 (human) TKPSEGTTLRVEDLV T426
MRE11A iso3 (human) TKPSEGTTLRVEDLV T429
MRE11A (mouse) KPASEGATLRVEDLV T427
MRE11A (rat) KPASEGTTLRVEDLV T427
K434-ub
LRVEDLVkQyFQTAE
0 3
MRE11A (human) LRVEDLVkQyFQTAE K434-ub
MRE11A iso2 (human) LRVEDLVKQYFQTAE K434
MRE11A iso3 (human) LRVEDLVKQYFQTAE K437
MRE11A (mouse) LRVEDLVKQYFQTAE K435
MRE11A (rat) LRVEDLVKQYFQTAE K435
Y436-p
VEDLVkQyFQTAEkN
0 1
MRE11A (human) VEDLVkQyFQTAEkN Y436-p
MRE11A iso2 (human) VEDLVKQYFQTAEKN Y436
MRE11A iso3 (human) VEDLVKQYFQTAEKN Y439
MRE11A (mouse) VEDLVKQYFQTAEkN Y437
MRE11A (rat) VEDLVKQYFQTAEKN Y437
K442-ub
QyFQTAEkNVQLsLL
0 12
MRE11A (human) QyFQTAEkNVQLsLL K442-ub
MRE11A iso2 (human) QYFQTAEKNVQLSLL K442
MRE11A iso3 (human) QYFQTAEKNVQLSLL K445
MRE11A (mouse) QYFQTAEkNVQLSLL K443-ub
MRE11A (rat) QYFQTAEKNVQLSLL K443
S447-p
AEkNVQLsLLTERGM
Upstream
0 1
Treatment
  • MLN8054
MRE11A (human) AEkNVQLsLLTERGM S447-p
MRE11A iso2 (human) AEKNVQLSLLTERGM S447
MRE11A iso3 (human) AEKNVQLSLLTERGM S450
MRE11A (mouse) AEkNVQLSLLTERGM S448
MRE11A (rat) AEKNVQLSLLTERGM S448
K464-ub
AVQEFVDkEEKDAIE
0 1
MRE11A (human) AVQEFVDkEEKDAIE K464-ub
MRE11A iso2 (human) AVQEFVDKEEKDAIE K464
MRE11A iso3 (human) AVQEFVDKEEKDAIE K467
MRE11A (mouse) AVQEFVDKEEKDAIE K465
MRE11A (rat) AVQEFVDKEEKDAIE K465
K475-ub
DAIEELVkYQLEktQ
0 2
MRE11A (human) DAIEELVkYQLEktQ K475-ub
MRE11A iso2 (human) DAIEELVKYQLEKTQ K475
MRE11A iso3 (human) DAIEELVKYQLEKTQ K478
MRE11A (mouse) DAIEELVKYQLEKTQ K476
MRE11A (rat) DAIEELVKYQLEKTQ K476
K480-ac
LVkYQLEktQRFLkE
0 1
MRE11A (human) LVkYQLEktQRFLkE K480-ac
MRE11A iso2 (human) LVKYQLEKTQRFLKE K480
MRE11A iso3 (human) LVKYQLEKTQRFLKE K483
MRE11A (mouse) LVKYQLEKTQRFLKE K481
MRE11A (rat) LVKYQLEKTQRFLKE K481
K480-ub
LVkYQLEktQRFLkE
0 2
MRE11A (human) LVkYQLEktQRFLkE K480-ub
MRE11A iso2 (human) LVKYQLEKTQRFLKE K480
MRE11A iso3 (human) LVKYQLEKTQRFLKE K483
MRE11A (mouse) LVKYQLEKTQRFLKE K481
MRE11A (rat) LVKYQLEKTQRFLKE K481
T481-p
VkYQLEktQRFLkER
Upstream
Downstream
1 0
Effects on Modified Protein
  • molecular association, regulation
Treatment
  • caffeine
  • DSBs
  • KU-55933
  • NU7026
  • okadaic_acid
MRE11A (human) VkYQLEktQRFLkER T481-p
MRE11A iso2 (human) VKYQLEKTQRFLKER T481
MRE11A iso3 (human) VKYQLEKTQRFLKER T484
MRE11A (mouse) VKYQLEKTQRFLKER T482
MRE11A (rat) VKYQLEKTQRFLKER T482
K486-ub
EktQRFLkERHIDAL
0 1
MRE11A (human) EktQRFLkERHIDAL K486-ub
MRE11A iso2 (human) EKTQRFLKERHIDAL K486
MRE11A iso3 (human) EKTQRFLKERHIDAL K489
MRE11A (mouse) EKTQRFLKERHIDAL K487
MRE11A (rat) EKTQRFLKERHIDAL K487
K496-ub
HIDALEDkIDEEVRR
0 1
MRE11A (human) HIDALEDkIDEEVRR K496-ub
MRE11A iso2 (human) HIDALEDKIDEEVRR K496
MRE11A iso3 (human) HIDALEDKIDEEVRR K499
MRE11A (mouse) HIDALEDKIDEEVRR K497
MRE11A (rat) HIDALEDKIDEEVRR K497
S531-p
TRARALRsQSEESAS
Upstream
Downstream
1 1
Effects on Modified Protein
  • molecular association, regulation
Treatment
  • caffeine
  • DSBs
  • KU-55933
  • NU7026
  • okadaic_acid
MRE11A (human) TRARALRsQSEESAS S531-p
MRE11A iso2 (human) TRARALRSQSEESAS S531
MRE11A iso3 (human) TRARALRSQSEESAS S534
MRE11A (mouse) SRARALRSQSETSTS S532
MRE11A (rat) SRARALRSQSENAAS S532
S558-p
AEQMANDsDDsISAA
Upstream
Downstream
1 9
Effects on Modified Protein
  • molecular association, regulation
  • protein stabilization
Kinase, in vitro:
  • CK2A1 (human)
Putative in vivo kinases:
  • CK2A1 (human)
MRE11A (human) AEQMANDsDDsISAA S558-p
MRE11A iso2 (human) AEQMANDSDDSISAA S558
MRE11A iso3 (human) AEQMANDSDDSISAA S561
MRE11A (mouse) SEQTANDSDDSLSAV S558
MRE11A (rat) TEQTADDSDDSQSAV S558
S561-p
MANDsDDsISAATNK
Upstream
Downstream
1 2
Effects on Modified Protein
  • molecular association, regulation
  • protein stabilization
Kinase, in vitro:
  • CK2A1 (human)
Putative in vivo kinases:
  • CK2A1 (human)
MRE11A (human) MANDsDDsISAATNK S561-p
MRE11A iso2 (human) MANDSDDSISAATNK S561
MRE11A iso3 (human) MANDSDDSISAATNK S564
MRE11A (mouse) TANDSDDSLSAVPSR S561
MRE11A (rat) TADDSDDSQSAVPSR S561
R570-me
SAATNKGrGrGrGrr
1 0
MRE11A (human) SAATNKGrGrGrGrr R570-me
MRE11A iso2 (human) SAATNKGRGRGRGRR R570
MRE11A iso3 (human) SAATNKGRGRGRGRR R573
MRE11A (mouse) SAVPSRGRGRGRGRR R570
MRE11A (rat) SAVPSRGRGRGRGRR R570
R570-m2
SAATNKGrGrGrGrr
Downstream
0 1
Effects on Biological Processes:
  • DNA repair, altered
MRE11A (human) SAATNKGrGrGrGrr R570-m2
MRE11A iso2 (human) SAATNKGRGRGRGRR R570
MRE11A iso3 (human) SAATNKGRGRGRGRR R573
MRE11A (mouse) SAVPSRGRGRGRGRR R570
MRE11A (rat) SAVPSRGRGRGRGRR R570
R572-me
ATNKGrGrGrGrrGG
1 0
MRE11A (human) ATNKGrGrGrGrrGG R572-me
MRE11A iso2 (human) ATNKGRGRGRGRRGG R572
MRE11A iso3 (human) ATNKGRGRGRGRRGG R575
MRE11A (mouse) VPSRGRGRGRGRRGA R572
MRE11A (rat) VPSRGRGRGRGRRGG R572
R572-m2
ATNKGrGrGrGrrGG
Downstream
0 1
Effects on Biological Processes:
  • DNA repair, altered
MRE11A (human) ATNKGrGrGrGrrGG R572-m2
MRE11A iso2 (human) ATNKGRGRGRGRRGG R572
MRE11A iso3 (human) ATNKGRGRGRGRRGG R575
MRE11A (mouse) VPSRGRGRGRGRRGA R572
MRE11A (rat) VPSRGRGRGRGRRGG R572
R574-me
NKGrGrGrGrrGGrG
1 0
MRE11A (human) NKGrGrGrGrrGGrG R574-me
MRE11A iso2 (human) NKGRGRGRGRRGGRG R574
MRE11A iso3 (human) NKGRGRGRGRRGGRG R577
MRE11A (mouse) SRGRGRGRGRRGARG R574
MRE11A (rat) SRGRGRGRGRRGGRG R574
R574-m2
NKGrGrGrGrrGGrG
Downstream
0 1
Effects on Biological Processes:
  • DNA repair, altered
MRE11A (human) NKGrGrGrGrrGGrG R574-m2
MRE11A iso2 (human) NKGRGRGRGRRGGRG R574
MRE11A iso3 (human) NKGRGRGRGRRGGRG R577
MRE11A (mouse) SRGRGRGRGRRGARG R574
MRE11A (rat) SRGRGRGRGRRGGRG R574
R576-me
GrGrGrGrrGGrGQN
1 0
MRE11A (human) GrGrGrGrrGGrGQN R576-me
MRE11A iso2 (human) GRGRGRGRRGGRGQN R576
MRE11A iso3 (human) GRGRGRGRRGGRGQN R579
MRE11A (mouse) GRGRGRGRRGARGQS R576
MRE11A (rat) GRGRGRGRRGGRGQS R576
R576-m2
GrGrGrGrrGGrGQN
Downstream
0 1
Effects on Biological Processes:
  • DNA repair, altered
MRE11A (human) GrGrGrGrrGGrGQN R576-m2
MRE11A iso2 (human) GRGRGRGRRGGRGQN R576
MRE11A iso3 (human) GRGRGRGRRGGRGQN R579
MRE11A (mouse) GRGRGRGRRGARGQS R576
MRE11A (rat) GRGRGRGRRGGRGQS R576
R577-me
rGrGrGrrGGrGQNS
1 0
MRE11A (human) rGrGrGrrGGrGQNS R577-me
MRE11A iso2 (human) RGRGRGRRGGRGQNS R577
MRE11A iso3 (human) RGRGRGRRGGRGQNS R580
MRE11A (mouse) RGRGRGRRGARGQSS R577
MRE11A (rat) RGRGRGRRGGRGQST R577
R577-m2
rGrGrGrrGGrGQNS
Downstream
0 1
Effects on Biological Processes:
  • DNA repair, altered
MRE11A (human) rGrGrGrrGGrGQNS R577-m2
MRE11A iso2 (human) RGRGRGRRGGRGQNS R577
MRE11A iso3 (human) RGRGRGRRGGRGQNS R580
MRE11A (mouse) RGRGRGRRGARGQSS R577
MRE11A (rat) RGRGRGRRGGRGQST R577
R580-me
GrGrrGGrGQNSASr
1 0
MRE11A (human) GrGrrGGrGQNSASr R580-me
MRE11A iso2 (human) GRGRRGGRGQNSASR R580
MRE11A iso3 (human) GRGRRGGRGQNSASR R583
MRE11A (mouse) GRGRRGARGQSSAPR R580
MRE11A (rat) GRGRRGGRGQSTAPR R580
R580-m2
GrGrrGGrGQNSASr
Downstream
0 1
Effects on Biological Processes:
  • DNA repair, altered
MRE11A (human) GrGrrGGrGQNSASr R580-m2
MRE11A iso2 (human) GRGRRGGRGQNSASR R580
MRE11A iso3 (human) GRGRRGGRGQNSASR R583
MRE11A (mouse) GRGRRGARGQSSAPR R580
MRE11A (rat) GRGRRGGRGQSTAPR R580
R587-me
rGQNSASrGGsQrGr
2 0
MRE11A (human) rGQNSASrGGsQrGr R587-me
MRE11A iso2 (human) RGQNSASRGGSQRGR R587
MRE11A iso3 (human) RGQNSASRGGSQRGR R590
MRE11A (mouse) RGQSSAPRGGSQRGR R587
MRE11A (rat) RGQSTAPRGGSQRGR R587
R587-m1
rGQNSASrGGsQrGr
0 8
MRE11A (human) rGQNSASrGGsQrGr R587-m1
MRE11A iso2 (human) RGQNSASRGGSQRGR R587
MRE11A iso3 (human) RGQNSASRGGSQRGR R590
MRE11A (mouse) RGQSSAPRGGSQRGR R587
MRE11A (rat) RGQSTAPRGGSQRGR R587
R587-m2
rGQNSASrGGsQrGr
Downstream
1 1
Effects on Biological Processes:
  • DNA repair, altered
MRE11A (human) rGQNSASrGGsQrGr R587-m2
MRE11A iso2 (human) RGQNSASRGGSQRGR R587
MRE11A iso3 (human) RGQNSASRGGSQRGR R590
MRE11A (mouse) RGQSSAPRGGSQRGR R587
MRE11A (rat) RGQSTAPRGGSQRGR R587
S590-p
NSASrGGsQrGrADt
Downstream
1 0
Effects on Modified Protein
  • molecular association, regulation
MRE11A (human) NSASrGGsQrGrADt S590-p
MRE11A iso2 (human) NSASRGGSQRGRAFk S590
MRE11A iso3 (human) NSASRGGSQRGRADT S593
MRE11A (mouse) SSAPRGGSQRGRDTG S590
MRE11A (rat) STAPRGGSQRGRDTG S590
R592-me
ASrGGsQrGrADtGL
1 0
MRE11A (human) ASrGGsQrGrADtGL R592-me
MRE11A iso2 (human) ASRGGSQRGRAFkST R592
MRE11A iso3 (human) ASRGGSQRGRADTGL R595
MRE11A (mouse) APRGGSQRGRDTGLE R592
MRE11A (rat) APRGGSQRGRDTGLG R592
R592-m2
ASrGGsQrGrADtGL
Downstream
0 1
Effects on Biological Processes:
  • DNA repair, altered
MRE11A (human) ASrGGsQrGrADtGL R592-m2
MRE11A iso2 (human) ASRGGSQRGRAFkST R592
MRE11A iso3 (human) ASRGGSQRGRADTGL R595
MRE11A (mouse) APRGGSQRGRDTGLE R592
MRE11A (rat) APRGGSQRGRDTGLG R592
R594-me
rGGsQrGrADtGLET
1 0
MRE11A (human) rGGsQrGrADtGLET R594-me
MRE11A iso2 (human) RGGSQRGRAFkSTRQ R594
MRE11A iso3 (human) RGGSQRGRADTGLET R597
MRE11A (mouse) RGGSQRGRDTGLEIT R594
MRE11A (rat) RGGSQRGRDTGLGIS R594
R594-m1
rGGsQrGrADtGLET
0 7
MRE11A (human) rGGsQrGrADtGLET R594-m1
MRE11A iso2 (human) RGGSQRGRAFkSTRQ R594
MRE11A iso3 (human) RGGSQRGRADTGLET R597
MRE11A (mouse) RGGSQRGRDTGLEIT R594
MRE11A (rat) RGGSQRGRDTGLGIS R594
R594-m2
rGGsQrGrADtGLET
Downstream
0 1
Effects on Biological Processes:
  • DNA repair, altered
MRE11A (human) rGGsQrGrADtGLET R594-m2
MRE11A iso2 (human) RGGSQRGRAFkSTRQ R594
MRE11A iso3 (human) RGGSQRGRADTGLET R597
MRE11A (mouse) RGGSQRGRDTGLEIT R594
MRE11A (rat) RGGSQRGRDTGLGIS R594
T597-p
sQrGrADtGLETSTr
Upstream
Downstream
1 26
Effects on Modified Protein
  • protein degradation
Kinase, in vitro:
  • p70S6K (human)
Putative in vivo kinases:
  • p70S6K (human)
MRE11A (human) sQrGrADtGLETSTr T597-p
MRE11A iso2 (human) gap -
MRE11A iso3 (human) SQRGRADTGLETSTR T600
MRE11A (mouse) GSQRGRDTGLEITTR T596
MRE11A (rat) GSQRGRDTGLGISTR T596
R604-m1
tGLETSTrSRNSkTA
0 11
MRE11A (human) tGLETSTrSRNSkTA R604-m1
MRE11A iso2 (human) gap -
MRE11A iso3 (human) TGLETSTRSRNSKTA R607
MRE11A (mouse) TGLEITTRGRSSKAT R603
MRE11A (rat) TGLGISTRGRSSKAT R603
K609-ac
STrSRNSkTAVsASr
0 4
MRE11A (human) STrSRNSkTAVsASr K609-ac
MRE11A iso2 (human) gap -
MRE11A iso3 (human) STRSRNSKTAVSASR K612
MRE11A (mouse) TTRGRSSKATSSTSR K608
MRE11A (rat) STRGRSSKATASTSR K608
S613-p
RNSkTAVsASrNMsI
0 1
MRE11A (human) RNSkTAVsASrNMsI S613-p
MRE11A iso2 (human) gap -
MRE11A iso3 (human) RNSKTAVSASRNMSI S616
MRE11A (mouse) RSSKATSSTSRNMsI S612
MRE11A (rat) RSSKATASTSRNMSI S612
R616-m1
kTAVsASrNMsIIDA
0 1
MRE11A (human) kTAVsASrNMsIIDA R616-m1
MRE11A iso2 (human) gap -
MRE11A iso3 (human) KTAVSASRNMSIIDA R619
MRE11A (mouse) KATSSTSRNMsIIDA R615
MRE11A (rat) KATASTSRNMSIIDA R615
S619-p
VsASrNMsIIDAFkS
0 8
MRE11A (human) VsASrNMsIIDAFkS S619-p
MRE11A iso2 (human) gap -
MRE11A iso3 (human) VSASRNMSIIDAFKS S622
MRE11A (mouse) SSTSRNMsIIDAFRS S618-p
MRE11A (rat) ASTSRNMSIIDAFRS S618
K625
MsIIDAFKSTRQQPS
0 1
MRE11A (human) MsIIDAFKSTRQQPS K625
MRE11A iso2 (human) SQRGRAFkSTRQQPS K597-ac
MRE11A iso3 (human) MSIIDAFKSTRQQPS K628
MRE11A (mouse) MsIIDAFRSTRQQPS R624
MRE11A (rat) MSIIDAFRSTRQQPS R624
K625-sm
MsIIDAFkSTRQQPS
0 1
MRE11A (human) MsIIDAFkSTRQQPS K625-sm
MRE11A iso2 (human) SQRGRAFKSTRQQPS K597
MRE11A iso3 (human) MSIIDAFKSTRQQPS K628
MRE11A (mouse) MsIIDAFRSTRQQPS R624
MRE11A (rat) MSIIDAFRSTRQQPS R624
S641
NVTTKNYSEVIEVDE
0 2
MRE11A (human) NVTTKNYSEVIEVDE S641
MRE11A iso2 (human) NVTTKNYSEVIEVDE S613
MRE11A iso3 (human) NVTTKNYSEVIEVDE S644
MRE11A (mouse) NVAPKNYsEtIEVDD S640-p
MRE11A (rat) NVATKNYSETIEVDE S640
V643
TTKNYSEVIEVDEsD
0 1
MRE11A (human) TTKNYSEVIEVDEsD V643
MRE11A iso2 (human) TTKNYSEVIEVDESD V615
MRE11A iso3 (human) TTKNYSEVIEVDESD V646
MRE11A (mouse) APKNYsEtIEVDDsD T642-p
MRE11A (rat) ATKNYSETIEVDEsD T642
S649-p
EVIEVDEsDVEEDIF
Upstream
Downstream
2 39
Effects on Biological Processes:
  • DNA repair, inhibited
  • cell cycle regulation
Kinase, in vitro:
  • CK2A1 (human)
  • PLK1 (human)
Putative in vivo kinases:
  • PLK1 (human)
MRE11A (human) EVIEVDEsDVEEDIF S649-p
MRE11A iso2 (human) EVIEVDESDVEEDIF S621
MRE11A iso3 (human) EVIEVDESDVEEDIF S652
MRE11A (mouse) EtIEVDDsDEDDIFP S648-p
MRE11A (rat) ETIEVDEsDDDDSFP S648-p
S667-p
SKTDQRWsstSsskI
0 1
MRE11A (human) SKTDQRWsstSsskI S667-p
MRE11A iso2 (human) SKTDQRWSSTSSSKI S639
MRE11A iso3 (human) SKTDQRWSSTSSSKI S670
MRE11A (mouse) SRADQRWSGTTSSkR S665
MRE11A (rat) SRADQRWSGTAPSkR S665
S668-p
KTDQRWsstSsskIM
0 1
MRE11A (human) KTDQRWsstSsskIM S668-p
MRE11A iso2 (human) KTDQRWSSTSSSKIM S640
MRE11A iso3 (human) KTDQRWSSTSSSKIM S671
MRE11A (mouse) RADQRWSGTTSSkRM G666
MRE11A (rat) RADQRWSGTAPSkRM G666
T669-p
TDQRWsstSsskIMs
0 4
MRE11A (human) TDQRWsstSsskIMs T669-p
MRE11A iso2 (human) TDQRWSSTSSSKIMS T641
MRE11A iso3 (human) TDQRWSSTSSSKIMS T672
MRE11A (mouse) ADQRWSGTTSSkRMs T667
MRE11A (rat) ADQRWSGTAPSkRMS T667
S671-p
QRWsstSsskIMsQs
0 1
MRE11A (human) QRWsstSsskIMsQs S671-p
MRE11A iso2 (human) QRWSSTSSSKIMSQS S643
MRE11A iso3 (human) QRWSSTSSSKIMSQS S674
MRE11A (mouse) QRWSGTTSSkRMsQS S669
MRE11A (rat) QRWSGTAPSkRMSQS P669
S672-p
RWsstSsskIMsQsQ
0 1
MRE11A (human) RWsstSsskIMsQsQ S672-p
MRE11A iso2 (human) RWSSTSSSKIMSQSQ S644
MRE11A iso3 (human) RWSSTSSSKIMSQSQ S675
MRE11A (mouse) RWSGTTSSkRMsQSQ S670
MRE11A (rat) RWSGTAPSkRMSQSQ S670
K673
WsstSssKIMsQsQV
0 9
MRE11A (human) WsstSssKIMsQsQV K673
MRE11A iso2 (human) WSSTSSSKIMSQSQV K645
MRE11A iso3 (human) WSSTSSSKIMSQSQV K676
MRE11A (mouse) WSGTTSSkRMsQSQT K671-ac