RYR2 (mouse)

LTP

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

HTP

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

Y196

ERYLHLSYGNSSWHV

RYR2 (human)	ERYLHLSyGNGSLHV	Y196-p
RYR2 iso2 (human)	ERYLHLSYGNGSLHV	Y196
RYR2 (mouse)	ERYLHLSYGNSSWHV	Y196
RYR2 (rat)	ERYLHLSYGNSSWRV	Y189
RYR2 (rabbit)	ERYLHLSYGNGSLHV	Y196
RYR2 (dog)	ERYLHLSYGNGSLHV	Y196

K304-ub

LRHVTTGkYLSLMED

RYR2 (human)	LRHVTTGKYLSLMED	K304
RYR2 iso2 (human)	LRHVTTGKYLSLMED	K304
RYR2 (mouse)	LRHVTTGkYLSLMED	K304-ub
RYR2 (rat)	LRHVTTGKYLSLMED	K297
RYR2 (rabbit)	LRHVTTGKYLSLMED	K304
RYR2 (dog)	LRHVTTGKYLSLMED	K304

K335-ac

AFAFRSSkEkLDVGV

RYR2 (human)	AFTFRSSKEKLDVGV	K335
RYR2 iso2 (human)	AFTFRSSKEKLDVGV	K335
RYR2 (mouse)	AFAFRSSkEkLDVGV	K335-ac
RYR2 (rat)	AFAFRSSKEKLDAGV	K328
RYR2 (rabbit)	AFTFRSSKEKLDGGV	K335
RYR2 (dog)	AFTFRSSKEKLDVGV	K335

K337-ac

AFRSSkEkLDVGVRK

RYR2 (human)	TFRSSKEKLDVGVRK	K337
RYR2 iso2 (human)	TFRSSKEKLDVGVRK	K337
RYR2 (mouse)	AFRSSkEkLDVGVRK	K337-ac
RYR2 (rat)	AFRSSKEKLDAGVRK	K330
RYR2 (rabbit)	TFRSSKEKLDGGVRK	K337
RYR2 (dog)	TFRSSKEKLDVGVRK	K337

K390

RMGSIQRKAIMHHEG

RYR2 (human)	RMGSIQRkAIMHHEG	K390-ub
RYR2 iso2 (human)	RMGSIQRKAIMHHEG	K390
RYR2 (mouse)	RMGSIQRKAIMHHEG	K390
RYR2 (rat)	RMGSIQRKAIMHHEG	K383
RYR2 (rabbit)	RMGSIQRKAIMHHEG	K390
RYR2 (dog)	RMGSIQRKAIMHHEG	K390

S406

MDDGLNLSRSQHEES

RYR2 (human)	MDDGISLsRSQHEES	S406-p
RYR2 iso2 (human)	MDDGISLSRSQHEES	S406
RYR2 (mouse)	MDDGLNLSRSQHEES	S406
RYR2 (rat)	MDDGLNLSRSQHEES	S399
RYR2 (rabbit)	MDDGLNLSRSQHEES	S406
RYR2 (dog)	MDDGLNLSRSQHEES	S406

Y819-p

KFLPPPGyAACyEAV

RYR2 (human)	KFLPPPGYAPCyEAV	Y819
RYR2 iso2 (human)	KFLPPPGYAPCYEAV	Y819
RYR2 (mouse)	KFLPPPGyAACyEAV	Y819-p
RYR2 (rat)	KFLPPPGYAACYEAV	Y812
RYR2 (rabbit)	KFLPPPGYAPCYEAV	Y819
RYR2 (dog)	KFLPPPGYAPCYEAV	Y819

Y823-p

PPGyAACyEAVLPKE

RYR2 (human)	PPGYAPCyEAVLPKE	Y823-p
RYR2 iso2 (human)	PPGYAPCYEAVLPKE	Y823
RYR2 (mouse)	PPGyAACyEAVLPKE	Y823-p
RYR2 (rat)	PPGYAACYEAVLPKE	Y816
RYR2 (rabbit)	PPGYAPCYEAVLPKE	Y823
RYR2 (dog)	PPGYAPCYEAVLPKE	Y823

Y931

LPEQERNYNLQMSLE

RYR2 (human)	LPEQERNYNLQMSLE	Y931
RYR2 iso2 (human)	LPEQERNYNLQMSLE	Y931
RYR2 (mouse)	LPEQERNYNLQMSLE	Y931
RYR2 (rat)	LPEQERNyNLQMSLE	Y924-p
RYR2 (rabbit)	LPEQERNYNLQMSLE	Y931
RYR2 (dog)	LPEQERNYNLQMSLE	Y931

Y970

KMKLPKNYQLTSGYK

RYR2 (human)	KMKLPKNyQLTSGYK	Y970-p
RYR2 iso2 (human)	KMKLPKNYQLTSGYK	Y970
RYR2 (mouse)	KMKLPKNYQLTSGYK	Y970
RYR2 (rat)	KMKLPKNYQLTSGYK	Y963
RYR2 (rabbit)	KMKLPKNYQLTSGYK	Y970
RYR2 (dog)	KMKLPKNYQLTSGYK	Y970

K998-ac

SQEAMVDkLAENAHN

RYR2 (human)	SQEAMVDKLAENAHN	K998
RYR2 iso2 (human)	SQEAMVDKLAENAHN	K998
RYR2 (mouse)	SQEAMVDkLAENAHN	K998-ac
RYR2 (rat)	SQEAMVDKLAENAHN	K991
RYR2 (rabbit)	SQEAMVDKLAENAHN	K998
RYR2 (dog)	SQEAMVDKLAENAHN	K998

K1141-ac

AFAFDGFkAQRWHQG

RYR2 (human)	AFAFDGFkAQRWHQG	K1141-ac
RYR2 iso2 (human)	AFAFDGFKAQRWHQG	K1141
RYR2 (mouse)	AFAFDGFkAQRWHQG	K1141-ac
RYR2 (rat)	AFAFDGFkAQRWHQG	K1134-ac
RYR2 (rabbit)	AFAFDGFKAQRWHQG	K1141
RYR2 (dog)	AFAFDGFKAQRWHQG	K1141

T1172

MVDMNEHTMMFTLNG

RYR2 (human)	MVDMNEHtMMFtLNG	T1172-p
RYR2 iso2 (human)	MVDMNEHTMMFTLNG	T1172
RYR2 (mouse)	MVDMNEHTMMFTLNG	T1172
RYR2 (rat)	MVDMNEHTMMFTLNG	T1165
RYR2 (rabbit)	MVDMNEHTMMFTLNG	T1172
RYR2 (dog)	MVDMTERTMMFTLNG	T1172

T1176

NEHTMMFTLNGEILL

RYR2 (human)	NEHtMMFtLNGEILL	T1176-p
RYR2 iso2 (human)	NEHTMMFTLNGEILL	T1176
RYR2 (mouse)	NEHTMMFTLNGEILL	T1176
RYR2 (rat)	NEHTMMFTLNGEILL	T1169
RYR2 (rabbit)	NEHTMMFTLNGEILL	T1176
RYR2 (dog)	TERTMMFTLNGEVLL	T1176

T1223-p

NFGKDVStLKYFTIC

RYR2 (human)	NFGKDVSTLKYFTIC	T1223
RYR2 iso2 (human)	NFGKDVSTLKYFTIC	T1223
RYR2 (mouse)	NFGKDVStLKYFTIC	T1223-p
RYR2 (rat)	NFGKDVSTLKYFTIC	T1216
RYR2 (rabbit)	NFGKDVSTLKYFTIC	T1223
RYR2 (dog)	NFGKDVSTLKYFTIC	T1223

K1253-ub

DITMWLSkRLPQFLQ

RYR2 (human)	DITMWLSKRLPQFLQ	K1253
RYR2 iso2 (human)	DITMWLSKRLPQFLQ	K1253
RYR2 (mouse)	DITMWLSkRLPQFLQ	K1253-ub
RYR2 (rat)	DITMWLSKRLPQFLQ	K1246
RYR2 (rabbit)	DITMWLSKRLPQFLQ	K1253
RYR2 (dog)	DITMWLSKRLPQFLQ	K1253

K1284-ub

IDSSPCLkVTQkSFG

RYR2 (human)	IDSSPCLKVTQKSFG	K1284
RYR2 iso2 (human)	IDSSPCLKVTQKSFG	K1284
RYR2 (mouse)	IDSSPCLkVTQkSFG	K1284-ub
RYR2 (rat)	IDSSPCLKVTQKSFG	K1277
RYR2 (rabbit)	IDSSPCLKVTQKSFG	K1284
RYR2 (dog)	IDSSPCLKVTQKSFG	K1284

K1288-ub

PCLkVTQkSFGSQNN

RYR2 (human)	PCLKVTQKSFGSQNS	K1288
RYR2 iso2 (human)	PCLKVTQKSFGSQNS	K1288
RYR2 (mouse)	PCLkVTQkSFGSQNN	K1288-ub
RYR2 (rat)	PCLKVTQKSFGSQNS	K1281
RYR2 (rabbit)	PCLKVTQKSFGSQNS	K1288
RYR2 (dog)	PCLKVTQKSFGSQNS	K1288

S1317-p

CAEVFSKsVAGGLPG

RYR2 (human)	CAEVFSKtVAGGLPG	T1317-p
RYR2 iso2 (human)	CAEVFSKTVAGGLPG	T1317
RYR2 (mouse)	CAEVFSKsVAGGLPG	S1317-p
RYR2 (rat)	CAEVFSKSVAGGIPG	S1310
RYR2 (rabbit)	CAEVFSKTVPGGLPG	T1317
RYR2 (dog)	CAEVFSKTVAGGLPG	T1317

S1341-p

LEDFDVDsDFEVLMK

RYR2 (human)	LEDYDADSDFEVLMK	S1341
RYR2 iso2 (human)	LEDYDADSDFEVLMK	S1341
RYR2 (mouse)	LEDFDVDsDFEVLMK	S1341-p
RYR2 (rat)	LEDFDVDsDFEVLMK	S1334-p
RYR2 (rabbit)	LEDYDADSDFEVLMK	S1341
RYR2 (dog)	LEDYDADSDFEVLMK	S1341

S1402-p

PDYSTGHsARLTEDV

RYR2 (human)	PDYSTSHSARLTEDV	S1402
RYR2 iso2 (human)	PDYSTSHSARLTEDV	S1402
RYR2 (mouse)	PDYSTGHsARLTEDV	S1402-p
RYR2 (rat)	PDYSTSHSARLTEDV	S1395
RYR2 (rabbit)	PDYSTSHSARLTEDV	S1402
RYR2 (dog)	PDYSTSHSARLTEDV	S1402

K1473-ub

TVTLGDEkGKVHESI

RYR2 (human)	TVTLGDEKGKVHESI	K1473
RYR2 iso2 (human)	TVTLGDEKGKVHESI	K1473
RYR2 (mouse)	TVTLGDEkGKVHESI	K1473-ub
RYR2 (rat)	TVTLGDEKGKVHESI	K1466
RYR2 (rabbit)	TVTLGDEKGKVHESI	K1473
RYR2 (dog)	TVTLGDEKGKVHESI	K1473

S1483

VHESIKRSNCYMVCA

RYR2 (human)	VHESIKRsNCyMVCA	S1483-p
RYR2 iso2 (human)	VHESIKRSNCYMVCA	S1483
RYR2 (mouse)	VHESIKRSNCYMVCA	S1483
RYR2 (rat)	VHESIKRSNCYMVCA	S1476
RYR2 (rabbit)	VHESIKRSNCYMVCA	S1483
RYR2 (dog)	VHESIKRSNCYMVCA	S1483

Y1486

SIKRSNCYMVCAGES

RYR2 (human)	SIKRsNCyMVCAGES	Y1486-p
RYR2 iso2 (human)	SIKRSNCYMVCAGES	Y1486
RYR2 (mouse)	SIKRSNCYMVCAGES	Y1486
RYR2 (rat)	SIKRSNCYMVCAGES	Y1479
RYR2 (rabbit)	SIKRSNCYMVCAGES	Y1486
RYR2 (dog)	SIKRSNCYMVCAGES	Y1486

S1495-p

VCAGESMsPGQGRNN

RYR2 (human)	VCAGESMSPGQGRNN	S1495
RYR2 iso2 (human)	VCAGESMSPGQGRNN	S1495
RYR2 (mouse)	VCAGESMsPGQGRNN	S1495-p
RYR2 (rat)	VCAGESMSPGQGRNN	S1488
RYR2 (rabbit)	VCAGESMSPGQGRNN	S1495
RYR2 (dog)	VCAGESMSPGQGRNN	S1495

K1562-ub

QFELGRIkNVMPLSA

RYR2 (human)	QFELGRIKNVMPLSA	K1561
RYR2 iso2 (human)	QFELGRIKNVMPLSA	K1561
RYR2 (mouse)	QFELGRIkNVMPLSA	K1562-ub
RYR2 (rat)	QFELGRIKNVMPLSA	K1555
RYR2 (rabbit)	QFELGRIKNVMPLSA	K1561
RYR2 (dog)	QFELGRIKNVMPLSA	K1561

K1789

EFPLDILKAkTIQML

RYR2 (human)	EFPLDILkSkTIQML	K1788-ac
RYR2 iso2 (human)	EFPLDILKSKTIQML	K1788
RYR2 (mouse)	EFPLDILKAkTIQML	K1789
RYR2 (rat)	EFPLDILKAKTIQML	K1782
RYR2 (rabbit)	EFPLDILKAKTIQML	K1788
RYR2 (dog)	EFPLDILKAKTIQML	K1788

K1791

PLDILKAKTIQMLTE

RYR2 (human)	PLDILkSkTIQMLTE	K1790-ac
RYR2 iso2 (human)	PLDILKSKTIQMLTE	K1790
RYR2 (mouse)	PLDILKAKTIQMLTE	K1791
RYR2 (rat)	PLDILKAKTIQMLTE	K1784
RYR2 (rabbit)	PLDILKAKTIQMLTE	K1790
RYR2 (dog)	PLDILKAKTIQMLTE	K1790

K1791-ub

PLDILKAkTIQMLTE

RYR2 (human)	PLDILkSKTIQMLTE	K1790
RYR2 iso2 (human)	PLDILKSKTIQMLTE	K1790
RYR2 (mouse)	PLDILKAkTIQMLTE	K1791-ub
RYR2 (rat)	PLDILKAKTIQMLTE	K1784
RYR2 (rabbit)	PLDILKAKTIQMLTE	K1790
RYR2 (dog)	PLDILKAKTIQMLTE	K1790

K1801-ub

QMLTEAVkEGSLHAR

RYR2 (human)	QMLTEAVKEGSLHAR	K1800
RYR2 iso2 (human)	QMLTEAVKEGSLHAR	K1800
RYR2 (mouse)	QMLTEAVkEGSLHAR	K1801-ub
RYR2 (rat)	QMLTEAVKEGSLHAR	K1794
RYR2 (rabbit)	QMLTEAVKEGSLHGR	K1800
RYR2 (dog)	QMLTEAVKEGSLHAR	K1800

T1864-p

VPEEEGGtPEkEIsI

RYR2 (human)	TPEEESDTLEKELSV	T1863
RYR2 iso2 (human)	TPEEESDTLEKELSV	T1863
RYR2 (mouse)	VPEEEGGtPEkEIsI	T1864-p
RYR2 (rat)	TPEEEGGAPEKEIsI	A1857
RYR2 (rabbit)	TPEEEGDTLEEEPSV	T1863
RYR2 (dog)	TPDEETEALEKEPCP	A1863

K1867-ub

EEGGtPEkEIsIEDA

RYR2 (human)	EESDTLEKELSVDDA	K1866
RYR2 iso2 (human)	EESDTLEKELSVDDA	K1866
RYR2 (mouse)	EEGGtPEkEIsIEDA	K1867-ub
RYR2 (rat)	EEGGAPEKEIsIDDS	K1860
RYR2 (rabbit)	EEGDTLEEEPSVEDT	E1866
RYR2 (dog)	EETEALEKEPCPEDS	K1866

S1870-p

GtPEkEIsIEDAkLE

RYR2 (human)	DTLEKELSVDDAKLQ	S1869
RYR2 iso2 (human)	DTLEKELSVDDAKLQ	S1869
RYR2 (mouse)	GtPEkEIsIEDAkLE	S1870-p
RYR2 (rat)	GAPEKEIsIDDSKLE	S1863-p
RYR2 (rabbit)	DTLEEEPSVEDTKLE	S1869
RYR2 (dog)	EALEKEPCPEDSKSE	C1869

K1875-ub

EIsIEDAkLEGEEEA

RYR2 (human)	ELSVDDAKLQGAGEE	K1874
RYR2 iso2 (human)	ELSVDDAKLQGAGEE	K1874
RYR2 (mouse)	EIsIEDAkLEGEEEA	K1875-ub
RYR2 (rat)	EIsIDDSKLEVKEEA	K1868
RYR2 (rabbit)	EPSVEDTKLEGAGEE	K1874
RYR2 (dog)	EPCPEDSKSEGAGEE	K1874

G1885-p

GEEEAKGgKRPKEGL

Downstream

Effects on Modified Protein

activity, induced

RYR2 (human)	GEEEAKGGkRPkEGL	G1886
RYR2 iso2 (human)	GEEEAKGGKRPKEGL	G1886
RYR2 (mouse)	GEEEAKGgKRPKEGL	G1885-p
RYR2 (rat)	VKEEAKAGKRPKEGL	G1878
RYR2 (rabbit)	GEEEAKVGKRPKEGL	G1886
RYR2 (dog)	GEEEAKGVKRPKEGL	V1886

K1886

EEEAKGgKRPKEGLL

RYR2 (human)	EEEAKGGkRPkEGLL	K1887-ac
RYR2 iso2 (human)	EEEAKGGKRPKEGLL	K1887
RYR2 (mouse)	EEEAKGgKRPKEGLL	K1886
RYR2 (rat)	KEEAKAGKRPKEGLL	K1879
RYR2 (rabbit)	EEEAKVGKRPKEGLL	K1887
RYR2 (dog)	EEEAKGVKRPKEGLL	K1887

K1889

AKGgKRPKEGLLQMK

RYR2 (human)	AKGGkRPkEGLLQMk	K1890-ac
RYR2 iso2 (human)	AKGGKRPKEGLLQMK	K1890
RYR2 (mouse)	AKGgKRPKEGLLQMK	K1889
RYR2 (rat)	AKAGKRPKEGLLQMK	K1882
RYR2 (rabbit)	AKVGKRPKEGLLQMK	K1890
RYR2 (dog)	AKGVKRPKEGLLQMK	K1890

K1896

KEGLLQMKLPEPVKL

RYR2 (human)	kEGLLQMkLPEPVkL	K1897-ac
RYR2 iso2 (human)	KEGLLQMKLPEPVKL	K1897
RYR2 (mouse)	KEGLLQMKLPEPVKL	K1896
RYR2 (rat)	KEGLLQMKLPEPVKL	K1889
RYR2 (rabbit)	KEGLLQMKLPEPVKL	K1897
RYR2 (dog)	KEGLLQMKLPEPVKL	K1897

K1902

MKLPEPVKLQMCLLL

RYR2 (human)	MkLPEPVkLQMCLLL	K1903-ac
RYR2 iso2 (human)	MKLPEPVKLQMCLLL	K1903
RYR2 (mouse)	MKLPEPVKLQMCLLL	K1902
RYR2 (rat)	MKLPEPVKLQMCLLL	K1895
RYR2 (rabbit)	MKLPEPVKLQMCLLL	K1903
RYR2 (dog)	MKLPEPVKLQMCLLL	K1903

Y1943

QDNQRFRYNEVMQAL

RYR2 (human)	QDNQRFRyNEVMQAL	Y1944-p
RYR2 iso2 (human)	QDNQRFRYNEVMQAL	Y1944
RYR2 (mouse)	QDNQRFRYNEVMQAL	Y1943
RYR2 (rat)	QDNQRFRYNEVMQAL	Y1936
RYR2 (rabbit)	QDNQRFRYNEVMQAL	Y1944
RYR2 (dog)	QDNQRFRYNEVMQAL	Y1944

T1961

AALTARKTREFRSPP

RYR2 (human)	AALTARKtKEFRSPP	T1962-p
RYR2 iso2 (human)	AALTARKTKEFRSPP	T1962
RYR2 (mouse)	AALTARKTREFRSPP	T1961
RYR2 (rat)	gap	-
RYR2 (rabbit)	AALTARKTKEFRSPP	T1962
RYR2 (dog)	AALTARKTKEFRSPP	T1962

S2030-p

TIRGRLLsLVEkVTY

Upstream

Downstream

Effects on Modified Protein

activity, induced
phosphorylation
protein conformation

Kinase, in vitro:

PKACA (human)

Putative in vivo kinases:

PKACA (human)

Regulatory protein:

PKACA (human)
plakophilin 2 (mouse)

Treatment

heart failure
isoproterenol
mPKI
okadaic_acid
wheel running test

RYR2 (human)	TIRGRLLsLVEKVTy	S2031-p
RYR2 iso2 (human)	TIRGRLLSLVEKVTY	S2031
RYR2 (mouse)	TIRGRLLsLVEkVTY	S2030-p
RYR2 (rat)	TIRGRLLsLVEKVTY	S2023-p
RYR2 (rabbit)	TIRGRLLsLVEKVTY	S2031-p
RYR2 (dog)	TIRGRLLsLVEKVTY	S2031-p

K2034-ub

RLLsLVEkVTYLKKK

RYR2 (human)	RLLsLVEKVTyLKKK	K2035
RYR2 iso2 (human)	RLLSLVEKVTYLKKK	K2035
RYR2 (mouse)	RLLsLVEkVTYLKKK	K2034-ub
RYR2 (rat)	RLLsLVEKVTYLKKK	K2027
RYR2 (rabbit)	RLLsLVEKVTYLKKK	K2035
RYR2 (dog)	RLLsLVEKVTYLKKK	K2035

Y2037

sLVEkVTYLKKKQAE

RYR2 (human)	sLVEKVTyLKKKQAE	Y2038-p
RYR2 iso2 (human)	SLVEKVTYLKKKQAE	Y2038
RYR2 (mouse)	sLVEkVTYLKKKQAE	Y2037
RYR2 (rat)	sLVEKVTYLKKKQAE	Y2030
RYR2 (rabbit)	sLVEKVTYLKKKQTE	Y2038
RYR2 (dog)	sLVEKVTYLKKKQAE	Y2038

S2072

MVRWAQESVIEDPEL

RYR2 (human)	MVRWAQEsVIEDPEL	S2073-p
RYR2 iso2 (human)	MVRWAQESVIEDPEL	S2073
RYR2 (mouse)	MVRWAQESVIEDPEL	S2072
RYR2 (rat)	MVRWAQESVIEDPEL	S2065
RYR2 (rabbit)	MVRWAQESVIEDPEL	S2073
RYR2 (dog)	MVRWAQESVIEDPDL	S2073

K2135

LLSVRMGKEEEKLMI

RYR2 (human)	LLSVRMGkEEEkLMI	K2136-m3
RYR2 iso2 (human)	LLSVRMGKEEEKLMI	K2136
RYR2 (mouse)	LLSVRMGKEEEKLMI	K2135
RYR2 (rat)	LLSVRMGKEEEKLMI	K2128
RYR2 (rabbit)	LLSVRMGKEEEKLMI	K2136
RYR2 (dog)	LLSVRMGKEEEKLMI	K2136

K2139

RMGKEEEKLMIRGLG

RYR2 (human)	RMGkEEEkLMIRGLG	K2140-m3
RYR2 iso2 (human)	RMGKEEEKLMIRGLG	K2140
RYR2 (mouse)	RMGKEEEKLMIRGLG	K2139
RYR2 (rat)	RMGKEEEKLMIRGLG	K2132
RYR2 (rabbit)	RMGKEEEKLMIRGLG	K2140
RYR2 (dog)	RMGKEEEKLMIRGLG	K2140

K2190

SKEITFPKMVANCCR

RYR2 (human)	SKEITFPkMVANCCR	K2191-ac
RYR2 iso2 (human)	SKEITFPKMVANCCR	K2191
RYR2 (mouse)	SKEITFPKMVANCCR	K2190
RYR2 (rat)	SKEITFPKMVANCCR	K2183
RYR2 (rabbit)	SKEITFPKMVANCCR	K2191
RYR2 (dog)	SKEITFPKMVANCCR	K2191

Y2201

NCCRFLCYFCRISRQ

RYR2 (human)	NCCRFLCyFCRISRQ	Y2202-p
RYR2 iso2 (human)	NCCRFLCYFCRISRQ	Y2202
RYR2 (mouse)	NCCRFLCYFCRISRQ	Y2201
RYR2 (rat)	NCCRFLCYFCRISRQ	Y2194
RYR2 (rabbit)	NCCRFLCYFCRISRQ	Y2202
RYR2 (dog)	NCCRFLCYFCRISRQ	Y2202

Y2219

AMFDHLSYLLENSSV

RYR2 (human)	AMFDHLSYLLENSSV	Y2220
RYR2 iso2 (human)	AMFDHLSYLLENSSV	Y2220
RYR2 (mouse)	AMFDHLSYLLENSSV	Y2219
RYR2 (rat)	AMFDHLSyLLENSSV	Y2212-p
RYR2 (rabbit)	AMFDHLSYLLENSSV	Y2220
RYR2 (dog)	AMFDHLSYLLENSSV	Y2220

S2230

NSSVGLASPAMRGST

RYR2 (human)	NSSVGLASPAMRGST	S2231
RYR2 iso2 (human)	NSSVGLASPAMRGST	S2231
RYR2 (mouse)	NSSVGLASPAMRGST	S2230
RYR2 (rat)	NSSVGLAsPAMRGST	S2223-p
RYR2 (rabbit)	NSSVGLASPAMRGST	S2231
RYR2 (dog)	NSSVGLASPAMRGST	S2231

S2362-p

DPSRDGPsPTSGssK

RYR2 (human)	DPSRDGPsPNSGsSK	S2363-p
RYR2 iso2 (human)	DPSRDGPSPNSGSSK	S2363
RYR2 (mouse)	DPSRDGPsPTSGssK	S2362-p
RYR2 (rat)	DPSRDGPSPTSGSSK	S2355
RYR2 (rabbit)	DPSRDGPSPTSGSSK	S2364
RYR2 (dog)	DPSRDGPSPTSGSSK	S2363

S2367-p

GPsPTSGssKTLDIE

Upstream

Putative in vivo kinases:

SPEG (mouse)

RYR2 (human)	GPsPNSGsSKTLDTE	S2368-p
RYR2 iso2 (human)	GPSPNSGSSKTLDTE	S2368
RYR2 (mouse)	GPsPTSGssKTLDIE	S2367-p
RYR2 (rat)	GPSPTSGSSKTLDAE	S2360
RYR2 (rabbit)	GPSPTSGSSKTLDTE	S2369
RYR2 (dog)	GPSPTSGSSKTLDTE	S2368

S2368-p

PsPTSGssKTLDIEE

RYR2 (human)	PsPNSGsSKTLDTEE	S2369
RYR2 iso2 (human)	PSPNSGSSKTLDTEE	S2369
RYR2 (mouse)	PsPTSGssKTLDIEE	S2368-p
RYR2 (rat)	PSPTSGSSKTLDAEE	S2361
RYR2 (rabbit)	PSPTSGSSKTLDTEE	S2370
RYR2 (dog)	PSPTSGSSKTLDTEE	S2369

K2449-ub

PTIAKDGkVVEPDMS

RYR2 (human)	PTIAKDGNVVEPDMS	N2450
RYR2 iso2 (human)	PTIAKDGNVVEPDMS	N2450
RYR2 (mouse)	PTIAKDGkVVEPDMS	K2449-ub
RYR2 (rat)	PTIAKDGKVVEPDMS	K2442
RYR2 (rabbit)	PTIAKDGNVVEPDMS	N2451
RYR2 (dog)	PTIAKDGNVVEPDMS	N2450

Y2518

MALALNRYLCTAVLP

RYR2 (human)	MALALNRyLCtAVLP	Y2519-p
RYR2 iso2 (human)	MALALNRYLCTAVLP	Y2519
RYR2 (mouse)	MALALNRYLCTAVLP	Y2518
RYR2 (rat)	MALALNRYLCTAVLP	Y2511
RYR2 (rabbit)	MALALNRYLCTAVLP	Y2520
RYR2 (dog)	MALALNRYLCTAVLP	Y2519

T2521

ALNRYLCTAVLPLLT

RYR2 (human)	ALNRyLCtAVLPLLt	T2522-p
RYR2 iso2 (human)	ALNRYLCTAVLPLLT	T2522
RYR2 (mouse)	ALNRYLCTAVLPLLT	T2521
RYR2 (rat)	ALNRYLCTAVLPLLT	T2514
RYR2 (rabbit)	ALNRYLCTAVLPLLT	T2523
RYR2 (dog)	ALNRYLCTAVLPLLT	T2522

T2528

TAVLPLLTRCAPLFA

RYR2 (human)	tAVLPLLtRCAPLFA	T2529-p
RYR2 iso2 (human)	TAVLPLLTRCAPLFA	T2529
RYR2 (mouse)	TAVLPLLTRCAPLFA	T2528
RYR2 (rat)	TAVLPLLTRCAPLFA	T2521
RYR2 (rabbit)	TAVLPLLTRCAPLFA	T2530
RYR2 (dog)	TAVLPLLTRCAPLFA	T2529

K2655-ub

FDALSQKkYEQELFK

RYR2 (human)	FDALSQKKYEQELFK	K2656
RYR2 iso2 (human)	FDALSQKKYEQELFK	K2656
RYR2 (mouse)	FDALSQKkYEQELFK	K2655-ub
RYR2 (rat)	FDALSQKKYEQELFK	K2648
RYR2 (rabbit)	FDALSQKKYEQELFK	K2657
RYR2 (dog)	FDALSQKKYEQELFK	K2656

S2696-p

EKQSSMDsEGNFNPQ

Upstream

Regulatory protein:

ADRB1 (mouse)

RYR2 (human)	EKQSSMDSEGNFNPQ	S2697
RYR2 iso2 (human)	EKQSSMDSEGNFNPQ	S2697
RYR2 (mouse)	EKQSSMDsEGNFNPQ	S2696-p
RYR2 (rat)	EKQSSMDsEGNFNPQ	S2689-p
RYR2 (rabbit)	EKQSSMDSEGNFNPQ	S2698
RYR2 (dog)	EKQSSMDSEGNFNPQ	S2697

S2750

GEIYSDSSKIQPLMK

RYR2 (human)	GEIYSDSsKVQPLMK	S2751-p
RYR2 iso2 (human)	GEIYSDSSKVQPLMK	S2751
RYR2 (mouse)	GEIYSDSSKIQPLMK	S2750
RYR2 (rat)	GEIYSDSSKIQPLMK	S2743
RYR2 (rabbit)	GEIYSDSSKIQPLMK	S2752
RYR2 (dog)	GEIYSDSSKVQPLMK	S2751

T2780

PIKESLKTMLAWGWR

RYR2 (human)	PIKESLKtMLAWGWR	T2781-p
RYR2 iso2 (human)	PIKESLKTMLAWGWR	T2781
RYR2 (mouse)	PIKESLKTMLAWGWR	T2780
RYR2 (rat)	PIKESLKTMLAWGWR	T2773
RYR2 (rabbit)	PIKESLKTMLAWGWR	T2782
RYR2 (dog)	PIKESLKTMLAWGWR	T2781

S2796-p

ERTREGDsMALYNRT

RYR2 (human)	ERTREGDSMALYNRT	S2797
RYR2 iso2 (human)	ERTREGDSMALYNRT	S2797
RYR2 (mouse)	ERTREGDsMALYNRT	S2796-p
RYR2 (rat)	ERTREGDSMALyNRT	S2789
RYR2 (rabbit)	ERTREGDSMALYNRT	S2798
RYR2 (dog)	ERTREGDSMALYNRT	S2797

Y2800

EGDsMALYNRTRRIs

RYR2 (human)	EGDSMALYNRTRRIs	Y2801
RYR2 iso2 (human)	EGDSMALYNRTRRIS	Y2801
RYR2 (mouse)	EGDsMALYNRTRRIs	Y2800
RYR2 (rat)	EGDSMALyNRTRRIs	Y2793-p
RYR2 (rabbit)	EGDSMALYNRTRRIs	Y2802
RYR2 (dog)	EGDSMALYNRTRRIs	Y2801

S2807-p

YNRTRRIsQtsQVsI

Upstream

Downstream

Effects on Modified Protein

activity, induced
molecular association, regulation

Effects on Biological Processes:

exocytosis, altered

Kinase, in vitro:

PKACA (human)
PKG1 (human)

Putative in vivo kinases:

CAMK2A (human)
PKACA (human)
PKACA (mouse)

Regulatory protein:

PKACA (human)
PKACA (mouse)
Spinophilin (mouse)

Treatment

adriamycin
autocamtide_inhibitory_peptide
fructose-rich diet
GLP-1
glutathione
H2O2
heart failure
inhibitor-1
ionizing_radiation
isoproterenol
mutation
propranolol
restraint stress
S107
Sapogenins
SD-208

RYR2 (human)	YNRTRRIsQTSQVsV	S2808-p
RYR2 iso2 (human)	YNRTRRISQTSQVSV	S2808
RYR2 (mouse)	YNRTRRIsQtsQVsI	S2807-p
RYR2 (rat)	yNRTRRIsQTsQVsI	S2800-p
RYR2 (rabbit)	YNRTRRIsQTSQVsV	S2809-p
RYR2 (dog)	YNRTRRIsQTSQVsV	S2808-p

T2809-p

RTRRIsQtsQVsIDA

RYR2 (human)	RTRRIsQTSQVsVDA	T2810
RYR2 iso2 (human)	RTRRISQTSQVSVDA	T2810
RYR2 (mouse)	RTRRIsQtsQVsIDA	T2809-p
RYR2 (rat)	RTRRIsQTsQVsIDA	T2802
RYR2 (rabbit)	RTRRIsQTSQVsVDA	T2811
RYR2 (dog)	RTRRIsQTSQVsVDA	T2810

S2810-p

TRRIsQtsQVsIDAA

RYR2 (human)	TRRIsQTSQVsVDAA	S2811
RYR2 iso2 (human)	TRRISQTSQVSVDAA	S2811
RYR2 (mouse)	TRRIsQtsQVsIDAA	S2810-p
RYR2 (rat)	TRRIsQTsQVsIDAA	S2803-p
RYR2 (rabbit)	TRRIsQTSQVsVDAA	S2812
RYR2 (dog)	TRRIsQTSQVsVDAA	S2811

S2813-p

IsQtsQVsIDAAHGY

Upstream

Downstream

Effects on Modified Protein

activity, induced
molecular association, regulation
phosphorylation
protein conformation

Effects on Biological Processes:

apoptosis, induced
signaling pathway regulation

Kinase, in vitro:

CAMK2A (mouse)
CAMK2D (human)

Phosphatases, in vitro:

PPP1CA (mouse)

Putative in vivo kinases:

CAMK2A (human)
CAMK2A (mouse)
CAMK2D (human)
CAMK2D (mouse)

Putative upstream phosphatases:

PPP1CA (mouse)

Regulatory protein:

CAMK2A (mouse)
nNOS (mouse)
PKACA (human)
plakophilin 2 (mouse)
Spinophilin (mouse)
tafazzin (human)
tafazzin (mouse)
TRPC7 (human)

Treatment

adriamycin
autocamtide_inhibitory_peptide
bisindolylmaleimide
calyculin_A
cpTOME
fructose-rich diet
GLP-1
glucose
glutathione
H2O2
heart failure
high_glucose
hydroxyurea
imatinib
increased heart rate
inhibitor-1
ionizing_radiation
ischemia
ischemia/reperfusion
isoproterenol
KN-93
LPS
MitoTEMPO
mutation
ouabain
pyridostigmine_bromide
resatorvid
TAC
wheel running test

RYR2 (human)	IsQTSQVsVDAAHGY	S2814-p
RYR2 iso2 (human)	ISQTSQVSVDAAHGY	S2814
RYR2 (mouse)	IsQtsQVsIDAAHGY	S2813-p
RYR2 (rat)	IsQTsQVsIDAAHGY	S2806-p
RYR2 (rabbit)	IsQTSQVsVDAAHGY	S2815-p
RYR2 (dog)	IsQTSQVsVDAAHGY	S2814-p

S2821-p

IDAAHGYsPRAIDMS

RYR2 (human)	VDAAHGYSPRAIDMS	S2822
RYR2 iso2 (human)	VDAAHGYSPRAIDMS	S2822
RYR2 (mouse)	IDAAHGYsPRAIDMS	S2821-p
RYR2 (rat)	IDAAHGYSPRAIDMS	S2814
RYR2 (rabbit)	VDAAHGYSPRAIDMS	S2823
RYR2 (dog)	VDAAHGYSPRAIDMS	S2822

K2862-ub

KKLELESkGGGNHPL

RYR2 (human)	KKMELESKGGGNHPL	K2863
RYR2 iso2 (human)	KKMELESKGGGNHPL	K2863
RYR2 (mouse)	KKLELESkGGGNHPL	K2862-ub
RYR2 (rat)	KKMELESKGGGNHPL	K2855
RYR2 (rabbit)	KKLELESKGGGNHPL	K2864
RYR2 (dog)	KKMELESKGGGNHPL	K2863

K2879-ub

PYDTLTAkEKAKDRE

RYR2 (human)	PYDTLTAKEKAKDRE	K2880
RYR2 iso2 (human)	PYDTLTAKEKAKDRE	K2880
RYR2 (mouse)	PYDTLTAkEKAKDRE	K2879-ub
RYR2 (rat)	PYDTLTAKEKAKDRE	K2872
RYR2 (rabbit)	PYDTLTAKEKAKDRE	K2881
RYR2 (dog)	PYDTLTAKEKAKDRE	K2880

S2898-p

IFKFLQIsGyVVSRG

RYR2 (human)	ILKFLQINGYAVSRG	N2899
RYR2 iso2 (human)	ILKFLQINGYAVSRG	N2899
RYR2 (mouse)	IFKFLQIsGyVVSRG	S2898-p
RYR2 (rat)	IFKFLQISGYAVSRG	S2891
RYR2 (rabbit)	ILKFLQINGYAVSRG	N2900
RYR2 (dog)	ILKFLQINGYAVSRG	N2899

Y2900-p

KFLQIsGyVVSRGFk

RYR2 (human)	KFLQINGYAVSRGFK	Y2901
RYR2 iso2 (human)	KFLQINGYAVSRGFK	Y2901
RYR2 (mouse)	KFLQIsGyVVSRGFk	Y2900-p
RYR2 (rat)	KFLQISGYAVSRGFK	Y2893
RYR2 (rabbit)	KFLQINGYAVSRGFK	Y2902
RYR2 (dog)	KFLQINGYAVSRGFK	Y2901

K2907-ub

yVVSRGFkDLDLDTP

RYR2 (human)	YAVSRGFKDLELDTP	K2908
RYR2 iso2 (human)	YAVSRGFKDLELDTP	K2908
RYR2 (mouse)	yVVSRGFkDLDLDTP	K2907-ub
RYR2 (rat)	YAVSRGFKDLDLDTP	K2900
RYR2 (rabbit)	YAVSRGFKDLELDTP	K2909
RYR2 (dog)	YAVSRGFKDLELDTP	K2908

Y2922

SIEKRFAYSFLQQLI

RYR2 (human)	SIEKRFAySFLQQLI	Y2923-p
RYR2 iso2 (human)	SIEKRFAYSFLQQLI	Y2923
RYR2 (mouse)	SIEKRFAYSFLQQLI	Y2922
RYR2 (rat)	SIEKRFAySFLQQLI	Y2915-p
RYR2 (rabbit)	SIEKRFAYSFLQQLI	Y2924
RYR2 (dog)	SIEKRFAYSFLQQLI	Y2923

S2946-p

ILEFDGGsRSKGEHF

RYR2 (human)	ILEFDGGSRGKGEHF	S2947
RYR2 iso2 (human)	ILEFDGGSRGKGEHF	S2947
RYR2 (mouse)	ILEFDGGsRSKGEHF	S2946-p
RYR2 (rat)	ILEFDGGSRSKGEHF	S2939
RYR2 (rabbit)	ILEFDGGSRSKGEHF	S2948
RYR2 (dog)	ILEFDGGGRSKGEHF	G2947

K3075-ub

EKTMENLkQGQFTHT

RYR2 (human)	EKTMENLKQGQFTHT	K3076
RYR2 iso2 (human)	EKTMENLKQGQFTHT	K3076
RYR2 (mouse)	EKTMENLkQGQFTHT	K3075-ub
RYR2 (rat)	EKTMENLKQGQFTHT	K3068
RYR2 (rabbit)	EKTMENLKQGQFTHT	K3077
RYR2 (dog)	EKTMENLKQGQFTHT	K3076

Y3227-p

LAESGIRyTQMPyMM

RYR2 (human)	LAESGIRYTQMPHVM	Y3228
RYR2 iso2 (human)	LAESGIRYTQMPHVM	Y3228
RYR2 (mouse)	LAESGIRyTQMPyMM	Y3227-p
RYR2 (rat)	LAESGIRYTQMPHMM	Y3220
RYR2 (rabbit)	LAESGIRYTQMPHVM	Y3229
RYR2 (dog)	LAESGIRYTQMPHVM	Y3228

Y3232-p

IRyTQMPyMMEVVLP

RYR2 (human)	IRYTQMPHVMEVILP	H3233
RYR2 iso2 (human)	IRYTQMPHVMEVILP	H3233
RYR2 (mouse)	IRyTQMPyMMEVVLP	Y3232-p
RYR2 (rat)	IRYTQMPHMMEVVLP	H3225
RYR2 (rabbit)	IRYTQMPHVMEVILP	H3234
RYR2 (dog)	IRYTQMPHVMEVILP	H3233

Y3244-p

VLPMLCSyMSRWWEH

RYR2 (human)	ILPMLCSYMSRWWEH	Y3245
RYR2 iso2 (human)	ILPMLCSYMSRWWEH	Y3245
RYR2 (mouse)	VLPMLCSyMSRWWEH	Y3244-p
RYR2 (rat)	VLPMLCSYMSRWWEH	Y3237
RYR2 (rabbit)	ILPMLCSYMSRWWEH	Y3246
RYR2 (dog)	ILPMLCSYMSRWWEH	Y3245

Y3284

GNILKIIYNNLGIDE

RYR2 (human)	GNILKIIyNNLGIDE	Y3285-p
RYR2 iso2 (human)	GNILKIIYNNLGIDE	Y3285
RYR2 (mouse)	GNILKIIYNNLGIDE	Y3284
RYR2 (rat)	GNILKIIyNNLGIDE	Y3277-p
RYR2 (rabbit)	GNILKIIYNNLGIDE	Y3286
RYR2 (dog)	GNILKIIYNNLGIDE	Y3285

K3296-ub

IDEGAWMkRLAVFSQ

RYR2 (human)	IDEGAWMKRLAVFsQ	K3297
RYR2 iso2 (human)	IDEGAWMKRLAVFSQ	K3297
RYR2 (mouse)	IDEGAWMkRLAVFSQ	K3296-ub
RYR2 (rat)	IDEGAWMKRLAVFSQ	K3289
RYR2 (rabbit)	IDEGAWMKRLAVFSQ	K3298
RYR2 (dog)	IDEGAWMKRLAVFSQ	K3297

S3302

MkRLAVFSQPIINKV

RYR2 (human)	MKRLAVFsQPIINKV	S3303-p
RYR2 iso2 (human)	MKRLAVFSQPIINKV	S3303
RYR2 (mouse)	MkRLAVFSQPIINKV	S3302
RYR2 (rat)	MKRLAVFSQPIINKV	S3295
RYR2 (rabbit)	MKRLAVFSQPIINKV	S3304
RYR2 (dog)	MKRLAVFSQPIINKV	S3303

K3324-ub

HFLPLMEkLKKkAAM

RYR2 (human)	HFLPLMEKLKKKAAT	K3325
RYR2 iso2 (human)	HFLPLMEKLKKKAAT	K3325
RYR2 (mouse)	HFLPLMEkLKKkAAM	K3324-ub
RYR2 (rat)	HFLPLMEKLKKKAAM	K3317
RYR2 (rabbit)	HFLPLMEKLKKKAAM	K3326
RYR2 (dog)	HFLPLMEKLKKKAAM	K3325

K3328-ub

LMEkLKKkAAMVVSE

RYR2 (human)	LMEKLKKKAATVVSE	K3329
RYR2 iso2 (human)	LMEKLKKKAATVVSE	K3329
RYR2 (mouse)	LMEkLKKkAAMVVSE	K3328-ub
RYR2 (rat)	LMEKLKKKAAMVVSE	K3321
RYR2 (rabbit)	LMEKLKKKAAMVVSE	K3330
RYR2 (dog)	LMEKLKKKAAMVVSE	K3329

Y3366

TTLARDLYAFYPLLI

RYR2 (human)	TTLARDLyAFyPLLI	Y3367-p
RYR2 iso2 (human)	TTLARDLYAFYPLLI	Y3367
RYR2 (mouse)	TTLARDLYAFYPLLI	Y3366
RYR2 (rat)	TTLARDLYAFYPLLI	Y3359
RYR2 (rabbit)	TTLARDLYAFYPLLI	Y3368
RYR2 (dog)	TTLARDLYAFYPLLI	Y3367

Y3369

ARDLYAFYPLLIRFV

RYR2 (human)	ARDLyAFyPLLIRFV	Y3370-p
RYR2 iso2 (human)	ARDLYAFYPLLIRFV	Y3370
RYR2 (mouse)	ARDLYAFYPLLIRFV	Y3369
RYR2 (rat)	ARDLYAFYPLLIRFV	Y3362
RYR2 (rabbit)	ARDLYAFYPLLIRFV	Y3371
RYR2 (dog)	ARDLYAFYPLLIRFV	Y3370

S3436

FLITDTKSkMSkAAI

RYR2 (human)	FLITDTKskMSkAAV	S3437-p
RYR2 iso2 (human)	FLITDTKSKMSKAAV	S3437
RYR2 (mouse)	FLITDTKSkMSkAAI	S3436
RYR2 (rat)	FLITDTKSKMSKAAI	S3429
RYR2 (rabbit)	FLITDTKSKMSKAAV	S3438
RYR2 (dog)	FLITDTKSKMSKAAV	S3437

K3437-m1

LITDTKSkMSkAAIS

RYR2 (human)	LITDTKskMSkAAVS	K3438-m1
RYR2 iso2 (human)	LITDTKSKMSKAAVS	K3438
RYR2 (mouse)	LITDTKSkMSkAAIS	K3437-m1
RYR2 (rat)	LITDTKSKMSKAAIS	K3430
RYR2 (rabbit)	LITDTKSKMSKAAVS	K3439
RYR2 (dog)	LITDTKSKMSKAAVS	K3438

K3440-m1

DTKSkMSkAAISDQE

RYR2 (human)	DTKskMSkAAVSDQE	K3441-m1
RYR2 iso2 (human)	DTKSKMSKAAVSDQE	K3441
RYR2 (mouse)	DTKSkMSkAAISDQE	K3440-m1
RYR2 (rat)	DTKSKMSKAAISDQE	K3433
RYR2 (rabbit)	DTKSKMSKAAVSDQE	K3442
RYR2 (dog)	DTKSKMSKAAVSDQE	K3441

Y3458

MKRKGDRYSMQTSLI

RYR2 (human)	MKRKGDRySMQTSLI	Y3459-p
RYR2 iso2 (human)	MKRKGDRYSMQTSLI	Y3459
RYR2 (mouse)	MKRKGDRYSMQTSLI	Y3458
RYR2 (rat)	MKRKGDRYSMQTSLI	Y3451
RYR2 (rabbit)	MKRKGDRYSMQTSLI	Y3460
RYR2 (dog)	MKRKGDRYSMQTSLI	Y3459

S3496

ALAKNRFSLKDTEEE

RYR2 (human)	ALAKNRFsLKDtEDE	S3497-p
RYR2 iso2 (human)	ALAKNRFSLKDTEDE	S3497
RYR2 (mouse)	ALAKNRFSLKDTEEE	S3496
RYR2 (rat)	ALAKNRFSLKDTEEE	S3489
RYR2 (rabbit)	ALAKNRFSLKATEDE	S3498
RYR2 (dog)	ALAKNRFSMKDTEDE	S3497

T3500

NRFSLKDTEEEVRDI

RYR2 (human)	NRFsLKDtEDEVRDI	T3501-p
RYR2 iso2 (human)	NRFSLKDTEDEVRDI	T3501
RYR2 (mouse)	NRFSLKDTEEEVRDI	T3500
RYR2 (rat)	NRFSLKDTEEEVRDV	T3493
RYR2 (rabbit)	NRFSLKATEDEVRDI	T3502
RYR2 (dog)	NRFSMKDTEDEVRDI	T3501

K3531-ub

RWQMALYkDLPNRTE

RYR2 (human)	RWQMALYKDLPNRTD	K3532
RYR2 iso2 (human)	RWQMALYKDLPNRTD	K3532
RYR2 (mouse)	RWQMALYkDLPNRTE	K3531-ub
RYR2 (rat)	RWQMALYKDLPNRAE	K3524
RYR2 (rabbit)	RWQMALYKDLPNRTE	K3533
RYR2 (dog)	RWQMALYKDLPNRTE	K3532

S3573-p

YTGRGYFsLVEHPQR

RYR2 (human)	RVGRRHYCLVEHPQR	C3574
RYR2 iso2 (human)	RVGRRHYCLVEHPQR	C3574
RYR2 (mouse)	YTGRGYFsLVEHPQR	S3573-p
RYR2 (rat)	gap	-
RYR2 (rabbit)	FIGRRYYNLVEHPQR	N3575
RYR2 (dog)	CMRRRYYSLVEHPQR	S3574

T3750

ISASKGETGPMVAAT

RYR2 (human)	ISASKGEtGPMVAAt	T3751-p
RYR2 iso2 (human)	ISASKGETGPMVAAT	T3759
RYR2 (mouse)	ISASKGETGPMVAAT	T3750
RYR2 (rat)	FSASKGETGPMVAAT	T3739
RYR2 (rabbit)	ISASKGETGPMVAAT	T3752
RYR2 (dog)	ISASKGDTGPMVAAT	T3751

T3757

TGPMVAATLKLGIAI

RYR2 (human)	tGPMVAAtLKLGIAI	T3758-p
RYR2 iso2 (human)	TGPMVAATLKLGIAI	T3766
RYR2 (mouse)	TGPMVAATLKLGIAI	T3757
RYR2 (rat)	TGPMVAATLKLGIAI	T3746
RYR2 (rabbit)	TGPMVAATLKLGIAI	T3759
RYR2 (dog)	TGPMVAATLKLGIAI	T3758

Y3779

VQQKMLDYLKEKKDV

RYR2 (human)	VQQKMLDyLKEKKDV	Y3780-p
RYR2 iso2 (human)	VQQKMLDYLKEKKDV	Y3788
RYR2 (mouse)	VQQKMLDYLKEKKDV	Y3779
RYR2 (rat)	VQQKMLDYLKEKKDV	Y3768
RYR2 (rabbit)	VQQKMLDYLKEKKDV	Y3781
RYR2 (dog)	VQQKMLDYLKEKKDV	Y3780

K4039

KEYDPDGKGVISKRD

RYR2 (human)	KEYDPDGkGVISKRD	K4040-ac
RYR2 iso2 (human)	KEYDPDGKGVISKRD	K4048
RYR2 (mouse)	KEYDPDGKGVISKRD	K4039
RYR2 (rat)	KEYDPDGKGVISKRD	K4028
RYR2 (rabbit)	KEYDPDGKGIISKRD	K4041
RYR2 (dog)	KEYDPDGKGVISKRD	K4040

K4049

ISKRDFHKAMEsHKH

RYR2 (human)	ISKRDFHkAMESHKH	K4050-ac
RYR2 iso2 (human)	ISKRDFHKAMESHKH	K4058
RYR2 (mouse)	ISKRDFHKAMEsHKH	K4049
RYR2 (rat)	ISKRDFHKAMESHKH	K4038
RYR2 (rabbit)	ISKRDFHKAMESHKH	K4051
RYR2 (dog)	ISKRDFHKAMESHKH	K4050

S4053-p

DFHKAMEsHKHYTQS

RYR2 (human)	DFHkAMESHKHYTQS	S4054
RYR2 iso2 (human)	DFHKAMESHKHYTQS	S4062
RYR2 (mouse)	DFHKAMEsHKHYTQS	S4053-p
RYR2 (rat)	DFHKAMESHKHYTQS	S4042
RYR2 (rabbit)	DFHKAMESHKHYTQS	S4055
RYR2 (dog)	DFHKAMESHKHYTQS	S4054

S4310

GFFRIVSSLLLGGSL

RYR2 (human)	GFFRIICsLLLGGsL	S4311-p
RYR2 iso2 (human)	GFFRIICSLLLGGSL	S4319
RYR2 (mouse)	GFFRIVSSLLLGGSL	S4310
RYR2 (rat)	GFFRIVSSLLLGGSL	S4299
RYR2 (rabbit)	GFFRIVCSLLLGGSL	S4312
RYR2 (dog)	GFFRIICSLLLGGSL	S4311

S4316

SSLLLGGSLVEGAKK

RYR2 (human)	CsLLLGGsLVEGAKK	S4317-p
RYR2 iso2 (human)	CSLLLGGSLVEGAKK	S4325
RYR2 (mouse)	SSLLLGGSLVEGAKK	S4316
RYR2 (rat)	SSLLLGGSLVEGAKK	S4305
RYR2 (rabbit)	CSLLLGGSLVEGAKK	S4318
RYR2 (dog)	CSLLLGGSLVEGAKK	S4317

Y4390-p

LKREGGQykLIPHNP

RYR2 (human)	LKREGGQyKLIPHNP	Y4391-p
RYR2 iso2 (human)	LKREGGQYKLIPHNP	Y4399
RYR2 (mouse)	LKREGGQykLIPHNP	Y4390-p
RYR2 (rat)	LKREGGQYKLIPHNP	Y4379
RYR2 (rabbit)	LKREGGQYKLIPHNP	Y4392
RYR2 (dog)	LKREGGQYKLIPHNP	Y4391

K4391-ub

KREGGQykLIPHNPN

RYR2 (human)	KREGGQyKLIPHNPN	K4392
RYR2 iso2 (human)	KREGGQYKLIPHNPN	K4400
RYR2 (mouse)	KREGGQykLIPHNPN	K4391-ub
RYR2 (rat)	KREGGQYKLIPHNPN	K4380
RYR2 (rabbit)	KREGGQYKLIPHNPN	K4393
RYR2 (dog)	KREGGQYKLIPHNPN	K4392

S4435-p

EEKEETKsEPEKAEG

RYR2 (human)	EEKEETKSEPEKAEG	S4437
RYR2 iso2 (human)	EEKEETKSEPEKAEG	S4445
RYR2 (mouse)	EEKEETKsEPEKAEG	S4435-p
RYR2 (rat)	EGKEETKSEPEKAEG	S4424
RYR2 (rabbit)	EEKEETKSEPEKAEG	S4438
RYR2 (dog)	EEKEENKSEPEKAEG	S4437

K4450

EDGEKEEKAKDEKSK

RYR2 (human)	EDGEKEEkAkEDkGk	K4452-ac
RYR2 iso2 (human)	EDGEKEEKAKEDKGK	K4460
RYR2 (mouse)	EDGEKEEKAKDEKSK	K4450
RYR2 (rat)	EDGEKEEKAKDDKGK	K4439
RYR2 (rabbit)	EDGEKEEKVKEDKGK	K4453
RYR2 (dog)	EDGEKEEKAKEDKGK	K4452

K4452

GEKEEKAKDEKSKQK

RYR2 (human)	GEKEEkAkEDkGkQK	K4454-ac
RYR2 iso2 (human)	GEKEEKAKEDKGKQK	K4462
RYR2 (mouse)	GEKEEKAKDEKSKQK	K4452
RYR2 (rat)	GEKEEKAKDDKGKQK	K4441
RYR2 (rabbit)	GEKEEKVKEDKGKQK	K4455
RYR2 (dog)	GEKEEKAKEDKGKQK	K4454

K4455

EEKAKDEKSKQKLRQ

RYR2 (human)	EEkAkEDkGkQKLRQ	K4457-ac
RYR2 iso2 (human)	EEKAKEDKGKQKLRQ	K4465
RYR2 (mouse)	EEKAKDEKSKQKLRQ	K4455
RYR2 (rat)	EEKAKDDKGKQKLRQ	K4444
RYR2 (rabbit)	EEKVKEDKGKQKLRQ	K4458
RYR2 (dog)	EEKAKEDKGKQKLRQ	K4457

K4457

KAKDEKSKQKLRQLH

RYR2 (human)	kAkEDkGkQKLRQLH	K4459-ac
RYR2 iso2 (human)	KAKEDKGKQKLRQLH	K4467
RYR2 (mouse)	KAKDEKSKQKLRQLH	K4457
RYR2 (rat)	KAKDDKGKQKLRQLH	K4446
RYR2 (rabbit)	KVKEDKGKQKLRQLH	K4460
RYR2 (dog)	KAKEDKGKQKLRQLH	K4459

S4549

VTNSLDSSPHRIIAV

RYR2 (human)	KVTSLDSsSHRIIAV	S4550-p
RYR2 iso2 (human)	KVTSLDSSSHRIIAV	S4558
RYR2 (mouse)	VTNSLDSSPHRIIAV	S4549
RYR2 (rat)	VTTSLDSSPHRIIAV	S4538
RYR2 (rabbit)	VTTSLDSSSHRIIAV	S4552
RYR2 (dog)	KVSSLDSGSPRIITV	G4550

Y4558-p

HRIIAVHyVLEEssG

RYR2 (human)	HRIIAVHYVLEESSG	Y4559
RYR2 iso2 (human)	HRIIAVHYVLEESSG	Y4567
RYR2 (mouse)	HRIIAVHyVLEEssG	Y4558-p
RYR2 (rat)	HRIIAVHYVLEESSG	Y4547
RYR2 (rabbit)	HRIIAVHYVLEESSG	Y4561
RYR2 (dog)	PRIITVHYVLEESSG	Y4559

S4563-p

VHyVLEEssGYMEPt

RYR2 (human)	VHYVLEESSGYMEPT	S4564
RYR2 iso2 (human)	VHYVLEESSGYMEPT	S4572
RYR2 (mouse)	VHyVLEEssGYMEPt	S4563-p
RYR2 (rat)	VHYVLEESSGYMEPT	S4552
RYR2 (rabbit)	VHYVLEESSGYMEPT	S4566
RYR2 (dog)	VHYVLEESSGYMEPT	S4564

S4564-p

HyVLEEssGYMEPtL

Upstream

Treatment

RYR2 (human)	HYVLEESSGYMEPTL	S4565
RYR2 iso2 (human)	HYVLEESSGYMEPTL	S4573
RYR2 (mouse)	HyVLEEssGYMEPtL	S4564-p
RYR2 (rat)	HYVLEESSGYMEPTL	S4553
RYR2 (rabbit)	HYVLEESSGYMEPTL	S4567
RYR2 (dog)	HYVLEESSGYMEPTL	S4565

T4570-p

ssGYMEPtLRILAIL

Upstream

Treatment

RYR2 (human)	SSGYMEPTLRILAIL	T4571
RYR2 iso2 (human)	SSGYMEPTLRILAIL	T4579
RYR2 (mouse)	ssGYMEPtLRILAIL	T4570-p
RYR2 (rat)	SSGYMEPTLRILAIL	T4559
RYR2 (rabbit)	SSGYMEPTLRILAIL	T4573
RYR2 (dog)	SSGYMEPTLRILAIL	T4571

S4694

PKKDSSLSAVLNSID

RYR2 (human)	PKKDSSLsAVLNSID	S4695-p
RYR2 iso2 (human)	PKKDSSLSAVLNSID	S4703
RYR2 (mouse)	PKKDSSLSAVLNSID	S4694
RYR2 (rat)	PKKDSSLSAVLNSID	S4683
RYR2 (rabbit)	PKKDSSLSAVLNSID	S4697
RYR2 (dog)	PKKDSSLSAVLNSID	S4695

Y4704

LNSIDVKYQMWKLGV

RYR2 (human)	LNSIDVKyQMWKLGV	Y4705-p
RYR2 iso2 (human)	LNSIDVKYQMWKLGV	Y4713
RYR2 (mouse)	LNSIDVKYQMWKLGV	Y4704
RYR2 (rat)	LNSIDVKYQMWKLGV	Y4693
RYR2 (rabbit)	LNSIDVKYQMWKLGV	Y4707
RYR2 (dog)	LNSIDVKYQMWKLGV	Y4705

Y4943

ESYVWKMYQERCWEF

RYR2 (human)	ESYVWKMyQERCWEF	Y4944-p
RYR2 iso2 (human)	ESYVWKMYQERCWEF	Y4952
RYR2 (mouse)	ESYVWKMYQERCWEF	Y4943
RYR2 (rat)	ESYVWKMYQERCWEF	Y4932
RYR2 (rabbit)	ESYVWKMYQERCWEF	Y4946
RYR2 (dog)	ESYVWKMYQERCWEF	Y4944