Other Species / Isoforms
  HRas (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

  HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
K5-m2
___MTEYkLVVVGAG
1 1
HRas (human) ___MTEYkLVVVGAG K5-m2
HRas (mouse) ___MTEYKLVVVGAG K5
HRas (rat) ___MTEYKLVVVGAG K5
Y32-p
QNHFVDEyDPtIEDs
Upstream
Downstream
3 11
Effects on Modified Protein
  • activity, inhibited
Effects on Biological Processes:
  • carcinogenesis, inhibited
  • signaling pathway regulation
Kinase, in vitro:
  • Src (human)
Phosphatases, in vitro:
  • SHP-2 (human)
Putative upstream phosphatases:
  • SHP-2 (human)
Regulatory protein:
  • PD-1 (human)
Treatment
  • SHP099
  • siRNA
HRas (human) QNHFVDEyDPtIEDs Y32-p
HRas (mouse) QNHFVDEYDPTIEDs Y32
HRas (rat) QNHFVDEYDPTIEDS Y32
T35-p
FVDEyDPtIEDsyRK
Downstream
1 0
Effects on Biological Processes:
  • apoptosis, induced
HRas (human) FVDEyDPtIEDsyRK T35-p
HRas (mouse) FVDEYDPTIEDsYRK T35
HRas (rat) FVDEYDPTIEDSYRK T35
S39-p
yDPtIEDsyRKQVVI
0 11
HRas (human) yDPtIEDsyRKQVVI S39-p
HRas (mouse) YDPTIEDsYRKQVVI S39-p
HRas (rat) YDPTIEDSYRKQVVI S39
Y40-p
DPtIEDsyRKQVVID
0 3
HRas (human) DPtIEDsyRKQVVID Y40-p
HRas (mouse) DPTIEDsYRKQVVID Y40
HRas (rat) DPTIEDSYRKQVVID Y40
Y64-p
DTAGQEEySAMRDQY
Upstream
3 6
Kinase, in vitro:
  • Src (human)
HRas (human) DTAGQEEySAMRDQY Y64-p
HRas (mouse) DTAGQEEYSAMRDQY Y64
HRas (rat) DTAGQEEYSAMRDQY Y64
Y96-p
SFEDIHQyREQIKRV
Upstream
1 1
Kinase, in vitro:
  • Src (human)
HRas (human) SFEDIHQyREQIKRV Y96-p
HRas (mouse) SFEDIHQYREQIkRV Y96
HRas (rat) SFEDIHQYREQIKRV Y96
K101
HQyREQIKRVKDSDD
0 1
HRas (human) HQyREQIKRVKDSDD K101
HRas (mouse) HQYREQIkRVKDSDD K101-ub
HRas (rat) HQYREQIKRVKDSDD K101
K117-ub
PMVLVGNkCDLAART
Downstream
1 1
Effects on Modified Protein
  • enzymatic activity, induced
HRas (human) PMVLVGNkCDLAART K117-ub
HRas (mouse) PMVLVGNKCDLAART K117
HRas (rat) PMVLVGNKCDLAART K117
Y137-p
AQDLARSyGIPYIEt
Upstream
Downstream
2 1
Effects on Modified Protein
  • molecular association, regulation
Kinase, in vitro:
  • Abl (human)
Putative in vivo kinases:
  • Arg (human)
Treatment
  • palmitate
HRas (human) AQDLARSyGIPYIEt Y137-p
HRas (mouse) AQDLARSYGIPYIET Y137
HRas (rat) AQDLARSYGIPYIET Y137
T144-p
yGIPYIEtsAktRQG
Upstream
Downstream
2 1
Effects on Modified Protein
  • molecular association, regulation
  • phosphorylation
  • protein degradation
  • ubiquitination
Effects on Biological Processes:
  • carcinogenesis, inhibited
  • cell growth, inhibited
  • signaling pathway regulation
  • transcription, inhibited
Kinase, in vitro:
  • GSK3B (human)
Putative in vivo kinases:
  • GSK3B (human)
Regulatory protein:
  • WNT3A (human)
Treatment
  • lithium
  • siRNA
HRas (human) yGIPYIEtsAktRQG T144-p
HRas (mouse) YGIPYIETSAkTRQG T144
HRas (rat) YGIPYIETSAKTRQG T144
S145-p
GIPYIEtsAktRQGV
0 1
HRas (human) GIPYIEtsAktRQGV S145-p
HRas (mouse) GIPYIETSAkTRQGV S145
HRas (rat) GIPYIETSAKTRQGV S145
K147-m1
PYIEtsAktRQGVED
1 1
HRas (human) PYIEtsAktRQGVED K147-m1
HRas (mouse) PYIETSAKTRQGVED K147
HRas (rat) PYIETSAKTRQGVED K147
K147-ub
PYIEtsAktRQGVED
1 1
HRas (human) PYIEtsAktRQGVED K147-ub
HRas (mouse) PYIETSAkTRQGVED K147-ub
HRas (rat) PYIETSAKTRQGVED K147
T148-p
YIEtsAktRQGVEDA
Upstream
Downstream
2 2
Effects on Modified Protein
  • molecular association, regulation
  • phosphorylation
  • protein degradation
  • ubiquitination
Effects on Biological Processes:
  • carcinogenesis, inhibited
  • cell growth, inhibited
  • signaling pathway regulation
  • transcription, inhibited
Kinase, in vitro:
  • GSK3B (human)
Putative in vivo kinases:
  • GSK3B (human)
Regulatory protein:
  • WNT3A (human)
Treatment
  • lithium
  • siRNA
HRas (human) YIEtsAktRQGVEDA T148-p
HRas (mouse) YIETSAkTRQGVEDA T148
HRas (rat) YIETSAKTRQGVEDA T148
Y157-p
QGVEDAFytLVREIR
0 18
HRas (human) QGVEDAFytLVREIR Y157-p
HRas (mouse) QGVEDAFYTLVREIR Y157
HRas (rat) QGVEDAFYTLVREIR Y157
T158-p
GVEDAFytLVREIRQ
0 1
HRas (human) GVEDAFytLVREIRQ T158-p
HRas (mouse) GVEDAFYTLVREIRQ T158
HRas (rat) GVEDAFYTLVREIRQ T158
K170-ub
IRQHKLRkLNPPDES
1 3
HRas (human) IRQHKLRkLNPPDES K170-ub
HRas (mouse) IRQHKLRkLNPPDEs K170-ub
HRas (rat) IRQHKLRKLNPPDES K170
S177
kLNPPDESGPGCMsC
1 1
HRas (human) kLNPPDESGPGCMsC S177
HRas (mouse) kLNPPDEsGPGCMSC S177-p
HRas (rat) KLNPPDESGPGCMSC S177
S183-p
ESGPGCMsCKCVLS_
Upstream
0 1
Kinase, in vitro:
  • GSK3B (human)
HRas (human) ESGPGCMsCKCVLS_ S183-p
HRas (mouse) EsGPGCMSCKCVLS_ S183
HRas (rat) ESGPGCMSCKCVLS_ S183