Other Species / Isoforms
  ARHGEF2 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

  HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
S2-p
______MsRIEsLtR
0 3
ARHGEF2 (human) ______MsRIEsLtR S2-p
ARHGEF2 iso2 (human) ______MSRIESLTR S2
ARHGEF2 iso3 (human) gap -
ARHGEF2 (mouse) ______MsRIESLTR S2-p
ARHGEF2 (rat) ______MSRIESLTR S2
ARHGEF2 (pig) gap -
S6-p
__MsRIEsLtRARID
0 1
ARHGEF2 (human) __MsRIEsLtRARID S6-p
ARHGEF2 iso2 (human) __MSRIESLTRARID S6
ARHGEF2 iso3 (human) gap -
ARHGEF2 (mouse) __MsRIESLTRARID S6
ARHGEF2 (rat) __MSRIESLTRARID S6
ARHGEF2 (pig) gap -
T8-p
MsRIEsLtRARIDRS
0 1
ARHGEF2 (human) MsRIEsLtRARIDRS T8-p
ARHGEF2 iso2 (human) MSRIESLTRARIDRS T8
ARHGEF2 iso3 (human) gap -
ARHGEF2 (mouse) MsRIESLTRARIDRS T8
ARHGEF2 (rat) MSRIESLTRARIDRS T8
ARHGEF2 (pig) gap -
K63-ub
CNKSITAkEALICPT
0 2
ARHGEF2 (human) CNKSITAkEALICPT K63-ub
ARHGEF2 iso2 (human) CNKSITAKEALICPT K63
ARHGEF2 iso3 (human) CNKSITAKEALICPT K36
ARHGEF2 (mouse) CNKSITAKEALICPT K63
ARHGEF2 (rat) CNKSITAKEALICPT K63
ARHGEF2 (pig) CNKSITAKEALICPT K36
K80-ub
VTIHNRCkDTLANCT
0 1
ARHGEF2 (human) VTIHNRCkDTLANCT K80-ub
ARHGEF2 iso2 (human) VTIHNRCKDTLANCT K80
ARHGEF2 iso3 (human) VTIHNRCKDTLANCT K53
ARHGEF2 (mouse) VTIHNRCKDTLANCT K80
ARHGEF2 (rat) VTIHNRCKDTLANCT K80
ARHGEF2 (pig) VTIHNRCKDTLANCT K53
K88-ub
DTLANCTkVKQKQQk
0 3
ARHGEF2 (human) DTLANCTkVKQKQQk K88-ub
ARHGEF2 iso2 (human) DTLANCTKVKQKQQK K88
ARHGEF2 iso3 (human) DTLANCTKVKQKQQK K61
ARHGEF2 (mouse) DTLANCTKVKQKQQK K88
ARHGEF2 (rat) DTLANCTKVKQKQQK K88
ARHGEF2 (pig) DTLANCTKVKQKQQK K61
K95-ub
kVKQKQQkAALLkNN
0 2
ARHGEF2 (human) kVKQKQQkAALLkNN K95-ub
ARHGEF2 iso2 (human) KVKQKQQKAALLKNN K95
ARHGEF2 iso3 (human) KVKQKQQKAALLKNN K68
ARHGEF2 (mouse) KVKQKQQKAALLRNN K95
ARHGEF2 (rat) KVKQKQQKAALLRNN K95
ARHGEF2 (pig) KVKQKQQKAALLKNN K68
K100-ub
QQkAALLkNNTALQS
0 10
ARHGEF2 (human) QQkAALLkNNTALQS K100-ub
ARHGEF2 iso2 (human) QQKAALLKNNTALQS K100
ARHGEF2 iso3 (human) QQKAALLKNNTALQS K73
ARHGEF2 (mouse) QQKAALLRNNtALQs R100
ARHGEF2 (rat) QQKAALLRNNTALQS R100
ARHGEF2 (pig) QQKAALLKNNTALQS K73
K100-m1
QQkAALLkNNTALQS
0 1
ARHGEF2 (human) QQkAALLkNNTALQS K100-m1
ARHGEF2 iso2 (human) QQKAALLKNNTALQS K100
ARHGEF2 iso3 (human) QQKAALLKNNTALQS K73
ARHGEF2 (mouse) QQKAALLRNNtALQs R100
ARHGEF2 (rat) QQKAALLRNNTALQS R100
ARHGEF2 (pig) QQKAALLKNNTALQS K73
T103
AALLkNNTALQSVsL
0 3
ARHGEF2 (human) AALLkNNTALQSVsL T103
ARHGEF2 iso2 (human) AALLKNNTALQSVSL T103
ARHGEF2 iso3 (human) AALLKNNTALQSVSL T76
ARHGEF2 (mouse) AALLRNNtALQsVsL T103-p
ARHGEF2 (rat) AALLRNNTALQSVSL T103
ARHGEF2 (pig) AALLKNNTALQSVSL T76
S107
kNNTALQSVsLRSKT
0 1
ARHGEF2 (human) kNNTALQSVsLRSKT S107
ARHGEF2 iso2 (human) KNNTALQSVSLRSKT S107
ARHGEF2 iso3 (human) KNNTALQSVSLRSKT S80
ARHGEF2 (mouse) RNNtALQsVsLRSKt S107-p
ARHGEF2 (rat) RNNTALQSVSLRSKT S107
ARHGEF2 (pig) KNNTALQSVSLRSKT S80
S109-p
NTALQSVsLRSKTtI
0 15
ARHGEF2 (human) NTALQSVsLRSKTtI S109-p
ARHGEF2 iso2 (human) NTALQSVSLRSKTTI S109
ARHGEF2 iso3 (human) NTALQSVSLRSKTTI S82
ARHGEF2 (mouse) NtALQsVsLRSKtTT S109-p
ARHGEF2 (rat) NTALQSVSLRSKTTT S109
ARHGEF2 (pig) NTALQSVSLRSKTTT S82
T114
SVsLRSKTtIRERPs
1 0
ARHGEF2 (human) SVsLRSKTtIRERPs T114
ARHGEF2 iso2 (human) SVSLRSKTTIRERPS T114
ARHGEF2 iso3 (human) SVSLRSKTTIRERPS T87
ARHGEF2 (mouse) sVsLRSKtTTRERPt T114-p
ARHGEF2 (rat) SVSLRSKTTTRERPT T114
ARHGEF2 (pig) SVSLRSKTTTRERPS T87
T115-p
VsLRSKTtIRERPss
0 1
ARHGEF2 (human) VsLRSKTtIRERPss T115-p
ARHGEF2 iso2 (human) VSLRSKTTIRERPSS T115
ARHGEF2 iso3 (human) VSLRSKTTIRERPSS T88
ARHGEF2 (mouse) VsLRSKtTTRERPts T115
ARHGEF2 (rat) VSLRSKTTTRERPTS T115
ARHGEF2 (pig) VSLRSKTTTRERPSS T88
S121-p
TtIRERPssAIyPsD
Upstream
0 30
Treatment
  • Y27632
ARHGEF2 (human) TtIRERPssAIyPsD S121-p
ARHGEF2 iso2 (human) TTIRERPSSAIYPSD S121
ARHGEF2 iso3 (human) TTIRERPSSAIYPSD S94
ARHGEF2 (mouse) tTTRERPtsAIyPSD T121-p
ARHGEF2 (rat) TTTRERPTSAIYPSD T121
ARHGEF2 (pig) TTTRERPSSAIYPSD S94
S122-p
tIRERPssAIyPsDs
Upstream
1 87
Treatment
  • Y27632
ARHGEF2 (human) tIRERPssAIyPsDs S122-p
ARHGEF2 iso2 (human) TIRERPSSAIYPSDS S122
ARHGEF2 iso3 (human) TIRERPSSAIYPSDS S95
ARHGEF2 (mouse) TTRERPtsAIyPSDs S122-p
ARHGEF2 (rat) TTRERPTSAIYPSDS S122
ARHGEF2 (pig) TTRERPSSAIYPSDS S95
Y125-p
ERPssAIyPsDsFRQ
0 78
ARHGEF2 (human) ERPssAIyPsDsFRQ Y125-p
ARHGEF2 iso2 (human) ERPSSAIYPSDSFRQ Y125
ARHGEF2 iso3 (human) ERPSSAIYPSDSFRQ Y98
ARHGEF2 (mouse) ERPtsAIyPSDsFRQ Y125-p
ARHGEF2 (rat) ERPTSAIYPSDSFRQ Y125
ARHGEF2 (pig) ERPSSAIYPSDSFRQ Y98
S127-p
PssAIyPsDsFRQsL
Upstream
0 8
Treatment
  • Y27632
ARHGEF2 (human) PssAIyPsDsFRQsL S127-p
ARHGEF2 iso2 (human) PSSAIYPSDSFRQSL S127
ARHGEF2 iso3 (human) PSSAIYPSDSFRQSL S100
ARHGEF2 (mouse) PtsAIyPSDsFRQSL S127
ARHGEF2 (rat) PTSAIYPSDSFRQSL S127
ARHGEF2 (pig) PSSAIYPSDSFRQSL S100
S129-p
sAIyPsDsFRQsLLG
Upstream
0 29
Treatment
  • Y27632
ARHGEF2 (human) sAIyPsDsFRQsLLG S129-p
ARHGEF2 iso2 (human) SAIYPSDSFRQSLLG S129
ARHGEF2 iso3 (human) SAIYPSDSFRQSLLG S102
ARHGEF2 (mouse) sAIyPSDsFRQSLLG S129-p
ARHGEF2 (rat) SAIYPSDSFRQSLLG S129
ARHGEF2 (pig) SAIYPSDSFRQSLLG S102
S133-p
PsDsFRQsLLGsRRG
Upstream
0 17
Treatment
  • Y27632
ARHGEF2 (human) PsDsFRQsLLGsRRG S133-p
ARHGEF2 iso2 (human) PSDSFRQSLLGSRRG S133
ARHGEF2 iso3 (human) PSDSFRQSLLGSRRG S106
ARHGEF2 (mouse) PSDsFRQSLLGsRRG S133
ARHGEF2 (rat) PSDSFRQSLLGsRRG S133
ARHGEF2 (pig) PSDSFRQSLLGSRRG S106
S137-p
FRQsLLGsRRGRssL
0 9
ARHGEF2 (human) FRQsLLGsRRGRssL S137-p
ARHGEF2 iso2 (human) FRQSLLGSRRGRSSL S137
ARHGEF2 iso3 (human) FRQSLLGSRRGRSSL S110
ARHGEF2 (mouse) FRQSLLGsRRGLssL S137-p
ARHGEF2 (rat) FRQSLLGsRRGLSSL S137-p
ARHGEF2 (pig) FRQSLLGSRRGRSPL S110
S142-p
LGsRRGRssLsLAks
0 20
ARHGEF2 (human) LGsRRGRssLsLAks S142-p
ARHGEF2 iso2 (human) LGSRRGRSSLSLAKS S142
ARHGEF2 iso3 (human) LGSRRGRSSLSLAKS S115
ARHGEF2 (mouse) LGsRRGLssLSLAKS S142-p
ARHGEF2 (rat) LGsRRGLSSLSLAKS S142
ARHGEF2 (pig) LGSRRGRSPLSLAKS S115
S143-p
GsRRGRssLsLAksV
Upstream
2 10
Putative in vivo kinases:
  • MARK2 (human)
Treatment
  • MLN8054
ARHGEF2 (human) GsRRGRssLsLAksV S143-p
ARHGEF2 iso2 (human) GSRRGRSSLSLAKSV S143
ARHGEF2 iso3 (human) GSRRGRSSLSLAKSV S116
ARHGEF2 (mouse) GsRRGLssLSLAKSV S143-p
ARHGEF2 (rat) GsRRGLSSLSLAKSV S143
ARHGEF2 (pig) GSRRGRSPLSLAKSV P116
S145-p
RRGRssLsLAksVst
0 1
ARHGEF2 (human) RRGRssLsLAksVst S145-p
ARHGEF2 iso2 (human) RRGRSSLSLAKSVST S145
ARHGEF2 iso3 (human) RRGRSSLSLAKSVST S118
ARHGEF2 (mouse) RRGLssLSLAKSVsT S145
ARHGEF2 (rat) RRGLSSLSLAKSVsT S145
ARHGEF2 (pig) RRGRSPLSLAKSVST S118
K148-ub
RssLsLAksVsttNI
0 7
ARHGEF2 (human) RssLsLAksVsttNI K148-ub
ARHGEF2 iso2 (human) RSSLSLAKSVSTTNI K148
ARHGEF2 iso3 (human) RSSLSLAKSVSTTNI K121
ARHGEF2 (mouse) LssLSLAKSVsTTNI K148
ARHGEF2 (rat) LSSLSLAKSVsTTNI K148
ARHGEF2 (pig) RSPLSLAKSVSTTNI K121
S149-p
ssLsLAksVsttNIA
Upstream
0 21
Treatment
  • ischemia
ARHGEF2 (human) ssLsLAksVsttNIA S149-p
ARHGEF2 iso2 (human) SSLSLAKSVSTTNIA S149
ARHGEF2 iso3 (human) SSLSLAKSVSTTNIA S122
ARHGEF2 (mouse) ssLSLAKSVsTTNIA S149
ARHGEF2 (rat) SSLSLAKSVsTTNIA S149
ARHGEF2 (pig) SPLSLAKSVSTTNIA S122
S151-p
LsLAksVsttNIAGH
Upstream
Downstream
1 57
Effects on Modified Protein
  • activity, induced
  • intracellular localization
  • molecular association, regulation
Effects on Biological Processes:
  • cell adhesion, induced
  • cytoskeletal reorganization
Kinase, in vitro:
  • MARK3 (human)
Putative in vivo kinases:
  • MARK3 (human)
Putative upstream phosphatases:
  • PPP2CA (human)
Regulatory protein:
  • LKB1 (human)
Treatment
  • anti-CD3
  • metastatic potential
ARHGEF2 (human) LsLAksVsttNIAGH S151-p
ARHGEF2 iso2 (human) LSLAKSVSTTNIAGH S151
ARHGEF2 iso3 (human) LSLAKSVSTTNIAGH S124
ARHGEF2 (mouse) LSLAKSVsTTNIAGH S151-p
ARHGEF2 (rat) LSLAKSVsTTNIAGH S151-p
ARHGEF2 (pig) LSLAKSVSTTNIAGH S124
T152-p
sLAksVsttNIAGHF
0 7
ARHGEF2 (human) sLAksVsttNIAGHF T152-p
ARHGEF2 iso2 (human) SLAKSVSTTNIAGHF T152
ARHGEF2 iso3 (human) SLAKSVSTTNIAGHF T125
ARHGEF2 (mouse) SLAKSVsTTNIAGHF T152
ARHGEF2 (rat) SLAKSVsTTNIAGHF T152
ARHGEF2 (pig) SLAKSVSTTNIAGHF T125
T153-p
LAksVsttNIAGHFN
0 3
ARHGEF2 (human) LAksVsttNIAGHFN T153-p
ARHGEF2 iso2 (human) LAKSVSTTNIAGHFN T153
ARHGEF2 iso3 (human) LAKSVSTTNIAGHFN T126
ARHGEF2 (mouse) LAKSVsTTNIAGHFN T153
ARHGEF2 (rat) LAKSVsTTNIAGHFN T153
ARHGEF2 (pig) LAKSVSTTNIAGHFN T126
S163-p
AGHFNDEsPLGLRRI
Upstream
0 44
Treatment
  • anti-CD3
  • ischemia
ARHGEF2 (human) AGHFNDEsPLGLRRI S163-p
ARHGEF2 iso2 (human) AGHFNDESPLGLRRI S163
ARHGEF2 iso3 (human) AGHFNDESPLGLRRI S136
ARHGEF2 (mouse) AGHFNDEsPLGLRQI S163-p
ARHGEF2 (rat) AGHFNDESPLGLRQI S163
ARHGEF2 (pig) AGHFNDESPLGLRRI S136
S172-p
LGLRRILsQstDsLN
Upstream
1 87
Kinase, in vitro:
  • Chk1 (human)
Putative in vivo kinases:
  • MARK2 (human)
ARHGEF2 (human) LGLRRILsQstDsLN S172-p
ARHGEF2 iso2 (human) LGLRRILSQSTDSLN S172
ARHGEF2 iso3 (human) LGLRRILSQSTDSLN S145
ARHGEF2 (mouse) LGLRQILsQstDsLN S172-p
ARHGEF2 (rat) LGLRQILsQsTDsLN S172-p
ARHGEF2 (pig) LGLRRILSQSTDSLN S145
S174-p
LRRILsQstDsLNMR
Upstream
0 111
Treatment
  • AZD1152
  • EGF
  • ischemia
  • metastatic potential
  • ZM447439
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ARHGEF2 (human) LRRILsQstDsLNMR S174-p
ARHGEF2 iso2 (human) LRRILSQSTDSLNMR S174
ARHGEF2 iso3 (human) LRRILSQSTDSLNMR S147
ARHGEF2 (mouse) LRQILsQstDsLNMR S174-p
ARHGEF2 (rat) LRQILsQsTDsLNMR S174-p
ARHGEF2 (pig) LRRILSQSTDSLNMR S147
T175-p
RRILsQstDsLNMRN
0 10
ARHGEF2 (human) RRILsQstDsLNMRN T175-p
ARHGEF2 iso2 (human) RRILSQSTDSLNMRN T175
ARHGEF2 iso3 (human) RRILSQSTDSLNMRN T148
ARHGEF2 (mouse) RQILsQstDsLNMRN T175-p
ARHGEF2 (rat) RQILsQsTDsLNMRN T175
ARHGEF2 (pig) RRILSQSTDSLNMRN T148
S177-p
ILsQstDsLNMRNRt
Upstream
0 29
Treatment
  • ischemia
ARHGEF2 (human) ILsQstDsLNMRNRt S177-p
ARHGEF2 iso2 (human) ILSQSTDSLNMRNRt S177
ARHGEF2 iso3 (human) ILSQSTDSLNMRNRT S150
ARHGEF2 (mouse) ILsQstDsLNMRNRT S177-p
ARHGEF2 (rat) ILsQsTDsLNMRNRT S177-p
ARHGEF2 (pig) ILSQSTDSLNMRNRT S150
T184-p
sLNMRNRtLsVEsLI
0 2
ARHGEF2 (human) sLNMRNRtLsVEsLI T184-p
ARHGEF2 iso2 (human) SLNMRNRtLsVEsLI T184-p
ARHGEF2 iso3 (human) SLNMRNRTLSVESLI T157
ARHGEF2 (mouse) sLNMRNRTLSVESLI T184
ARHGEF2 (rat) sLNMRNRTLSVESLI T184
ARHGEF2 (pig) SLNMRNRTLSVESLI T157
S186-p
NMRNRtLsVEsLIDE
Upstream
1 2
Putative in vivo kinases:
  • MARK2 (human)
ARHGEF2 (human) NMRNRtLsVEsLIDE S186-p
ARHGEF2 iso2 (human) NMRNRtLsVEsLIDE S186-p
ARHGEF2 iso3 (human) NMRNRTLSVESLIDE S159
ARHGEF2 (mouse) NMRNRTLSVESLIDE S186
ARHGEF2 (rat) NMRNRTLSVESLIDE S186
ARHGEF2 (pig) NMRNRTLSVESLIDE S159
S189-p
NRtLsVEsLIDEAEV
0 3
ARHGEF2 (human) NRtLsVEsLIDEAEV S189-p
ARHGEF2 iso2 (human) NRtLsVEsLIDEEVI S189-p
ARHGEF2 iso3 (human) NRTLSVESLIDEEVI S162
ARHGEF2 (mouse) NRTLSVESLIDEGVE S189
ARHGEF2 (rat) NRTLSVESLIDEGVE S189
ARHGEF2 (pig) NRTLSVESLIDEGAE S162
K230-ub
SSFLQQHkKEVMkQQ
0 1
ARHGEF2 (human) SSFLQQHkKEVMkQQ K230-ub
ARHGEF2 iso2 (human) SSFLQQHKKEVMKQQ K229
ARHGEF2 iso3 (human) SSFLQQHKKEVMKQQ K202
ARHGEF2 (mouse) SSFLQQHKKEVMKKQ K231
ARHGEF2 (rat) SSFLQQHKKEVMKKQ K231
ARHGEF2 (pig) SSFLQQHKKEVMKQQ K204
K235-ub
QHkKEVMkQQDVIYE
0 1
ARHGEF2 (human) QHkKEVMkQQDVIYE K235-ub
ARHGEF2 iso2 (human) QHKKEVMKQQDVIYE K234
ARHGEF2 iso3 (human) QHKKEVMKQQDVIYE K207
ARHGEF2 (mouse) QHKKEVMKKQDVIYE K236
ARHGEF2 (rat) QHKKEVMKKQDVIyE K236
ARHGEF2 (pig) QHKKEVMKQQDVIYE K209
Y241
MkQQDVIYELIQTEL
0 5
ARHGEF2 (human) MkQQDVIYELIQTEL Y241
ARHGEF2 iso2 (human) MKQQDVIYELIQTEL Y240
ARHGEF2 iso3 (human) MKQQDVIYELIQTEL Y213
ARHGEF2 (mouse) MKKQDVIYELIQTEL Y242
ARHGEF2 (rat) MKKQDVIyELIQTEL Y242-p
ARHGEF2 (pig) MKQQDVIYELIQTEL Y215
K255-ub
LHHVRTLkIMTRLFR
0 2
ARHGEF2 (human) LHHVRTLkIMTRLFR K255-ub
ARHGEF2 iso2 (human) LHHVRTLKIMTRLFR K254
ARHGEF2 iso3 (human) LHHVRTLKIMTRLFR K227
ARHGEF2 (mouse) LHHVRTLKIMTRLFR K256
ARHGEF2 (rat) LHHVRTLKIMTRLFR K256
ARHGEF2 (pig) LHHVRTLKIMTRLFR K229
S295-p
DIHTRFLsQLLERRR
0 2
ARHGEF2 (human) DIHTRFLsQLLERRR S295-p
ARHGEF2 iso2 (human) DIHTRFLSQLLERRR S294
ARHGEF2 iso3 (human) DIHTRFLSQLLERRR S267
ARHGEF2 (mouse) DIHTRFLNQLLERRR N296
ARHGEF2 (rat) DIHTRFLsQLLERRR S296-p
ARHGEF2 (pig) DIHTRFLSQLLERRR S269
S309-p
RQALCPGstRNFVIH
0 2
ARHGEF2 (human) RQALCPGstRNFVIH S309-p
ARHGEF2 iso2 (human) RQALCPGSTRNFVIH S308
ARHGEF2 iso3 (human) RQALCPGSTRNFVIH S281
ARHGEF2 (mouse) RQALCPGSTRNFVIH S310
ARHGEF2 (rat) RQALCPGSTRNFVIH S310
ARHGEF2 (pig) RQALCPGSPRNFVIH S283
T310-p
QALCPGstRNFVIHR
0 2
ARHGEF2 (human) QALCPGstRNFVIHR T310-p
ARHGEF2 iso2 (human) QALCPGSTRNFVIHR T309
ARHGEF2 iso3 (human) QALCPGSTRNFVIHR T282
ARHGEF2 (mouse) QALCPGSTRNFVIHR T311
ARHGEF2 (rat) QALCPGSTRNFVIHR T311
ARHGEF2 (pig) QALCPGSPRNFVIHR P284
K336-ub
PSAEQMCkTYSEFCS
0 4
ARHGEF2 (human) PSAEQMCkTYSEFCS K336-ub
ARHGEF2 iso2 (human) PSAEQMCKTYSEFCS K335
ARHGEF2 iso3 (human) PSAEQMCKTYSEFCS K308
ARHGEF2 (mouse) SNAEQMRKTYSEFCS K337
ARHGEF2 (rat) SNAEQMRKTySEFCS K337
ARHGEF2 (pig) PSADQMRKTYSEFCS K310
Y338
AEQMCkTYSEFCSRH
0 1
ARHGEF2 (human) AEQMCkTYSEFCSRH Y338
ARHGEF2 iso2 (human) AEQMCKTYSEFCSRH Y337
ARHGEF2 iso3 (human) AEQMCKTYSEFCSRH Y310
ARHGEF2 (mouse) AEQMRKTYSEFCSRH Y339
ARHGEF2 (rat) AEQMRKTySEFCSRH Y339-p
ARHGEF2 (pig) ADQMRKTYSEFCSRH Y312
K347-ub
EFCSRHSkALKLYkE
0 1
ARHGEF2 (human) EFCSRHSkALKLYkE K347-ub
ARHGEF2 iso2 (human) EFCSRHSKALKLYKE K346
ARHGEF2 iso3 (human) EFCSRHSKALKLYKE K319
ARHGEF2 (mouse) EFCSRHTKALKLYkE K348
ARHGEF2 (rat) EFCSRHTKALKLYKE K348
ARHGEF2 (pig) EFCSRHTKALKLYKE K321
K353-ac
SkALKLYkELyARDK
0 1
ARHGEF2 (human) SkALKLYkELyARDK K353-ac
ARHGEF2 iso2 (human) SKALKLYKELYARDK K352
ARHGEF2 iso3 (human) SKALKLYKELYARDK K325
ARHGEF2 (mouse) TKALKLYKELYARDK K354
ARHGEF2 (rat) TKALKLYKELYARDK K354
ARHGEF2 (pig) TKALKLYKELYARDK K327
K353-ub
SkALKLYkELyARDK
0 13
ARHGEF2 (human) SkALKLYkELyARDK K353-ub
ARHGEF2 iso2 (human) SKALKLYKELYARDK K352
ARHGEF2 iso3 (human) SKALKLYKELYARDK K325
ARHGEF2 (mouse) TKALKLYkELYARDK K354-ub
ARHGEF2 (rat) TKALKLYKELYARDK K354
ARHGEF2 (pig) TKALKLYKELYARDK K327
Y356-p
LKLYkELyARDKRFQ
0 2
ARHGEF2 (human) LKLYkELyARDKRFQ Y356-p
ARHGEF2 iso2 (human) LKLYKELYARDKRFQ Y355
ARHGEF2 iso3 (human) LKLYKELYARDKRFQ Y328
ARHGEF2 (mouse) LKLYkELYARDKRFQ Y357
ARHGEF2 (rat) LKLYKELYARDKRFQ Y357
ARHGEF2 (pig) LKLYKELYARDKRFQ Y330
K376-m1
VTRPAVLkRHGVQEC
0 1
ARHGEF2 (human) VTRPAVLkRHGVQEC K376-m1
ARHGEF2 iso2 (human) VTRPAVLKRHGVQEC K375
ARHGEF2 iso3 (human) VTRPAVLKRHGVQEC K348
ARHGEF2 (mouse) MTRSAVLKRHGVQEC K377
ARHGEF2 (rat) MTRSAVLKRHGVQEC K377
ARHGEF2 (pig) VTRSAVLKRHGVQEC K350
T392-p
LLVTQRItkyPLLIS
0 1
ARHGEF2 (human) LLVTQRItkyPLLIS T392-p
ARHGEF2 iso2 (human) LLVTQRITKYPLLIS T391
ARHGEF2 iso3 (human) LLVTQRITKYPLLIS T364
ARHGEF2 (mouse) LLVTQRITKyPVLIN T393
ARHGEF2 (rat) LLVTQRITKYPVLIN T393
ARHGEF2 (pig) LLVTQRITKYPVLIS T366
K393-ub
LVTQRItkyPLLISR
0 1
ARHGEF2 (human) LVTQRItkyPLLISR K393-ub
ARHGEF2 iso2 (human) LVTQRITKYPLLISR K392
ARHGEF2 iso3 (human) LVTQRITKYPLLISR K365
ARHGEF2 (mouse) LVTQRITKyPVLINR K394
ARHGEF2 (rat) LVTQRITKYPVLINR K394
ARHGEF2 (pig) LVTQRITKYPVLISR K367
Y394-p
VTQRItkyPLLISRI
1 1
ARHGEF2 (human) VTQRItkyPLLISRI Y394-p
ARHGEF2 iso2 (human) VTQRITKYPLLISRI Y393
ARHGEF2 iso3 (human) VTQRITKYPLLISRI Y366
ARHGEF2 (mouse) VTQRITKyPVLINRI Y395-p
ARHGEF2 (rat) VTQRITKYPVLINRI Y395
ARHGEF2 (pig) VTQRITKYPVLISRI Y368
R412
SHGIEEERQDLTTAL
0 2
ARHGEF2 (human) SHGIEEERQDLTTAL R412
ARHGEF2 iso2 (human) SHGIEEERQDLTTAL R411
ARHGEF2 iso3 (human) SHGIEEERQDLTTAL R384
ARHGEF2 (mouse) SHGVEEEYQDLASAL Y413
ARHGEF2 (rat) SHGIEEEyQDLAAAL Y413-p
ARHGEF2 (pig) THGIEEERQDLTTAL R386
S427-p
GLVKELLsNVDEGIy
0 1
ARHGEF2 (human) GLVKELLsNVDEGIy S427-p
ARHGEF2 iso2 (human) GLVKELLSNVDEGIY S426
ARHGEF2 iso3 (human) GLVKELLSNVDEGIY S399
ARHGEF2 (mouse) GLVKELLSNVDQDVH S428
ARHGEF2 (rat) GLVKELLSNVDQDVH S428
ARHGEF2 (pig) GLVKELLSNVDQDVH S401
Y434-p
sNVDEGIyQLEkGAR
0 39
ARHGEF2 (human) sNVDEGIyQLEkGAR Y434-p
ARHGEF2 iso2 (human) SNVDEGIYQLEKGAR Y433
ARHGEF2 iso3 (human) SNVDEGIYQLEKGAR Y406
ARHGEF2 (mouse) SNVDQDVHELEKEAR H435
ARHGEF2 (rat) SNVDQDVHELEkEAR H435
ARHGEF2 (pig) SNVDQDVHELEKGAR H408
K438
EGIyQLEKGARLQEI
0 1
ARHGEF2 (human) EGIyQLEKGARLQEI K438
ARHGEF2 iso2 (human) EGIYQLEKGARLQEI K437
ARHGEF2 iso3 (human) EGIYQLEKGARLQEI K410
ARHGEF2 (mouse) QDVHELEKEARLQEI K439
ARHGEF2 (rat) QDVHELEkEARLQEI K439-ac
ARHGEF2 (pig) QDVHELEKGARLQEI K412
K438-ub
EGIyQLEkGARLQEI
0 19
ARHGEF2 (human) EGIyQLEkGARLQEI K438-ub
ARHGEF2 iso2 (human) EGIYQLEKGARLQEI K437
ARHGEF2 iso3 (human) EGIYQLEKGARLQEI K410
ARHGEF2 (mouse) QDVHELEKEARLQEI K439
ARHGEF2 (rat) QDVHELEKEARLQEI K439
ARHGEF2 (pig) QDVHELEKGARLQEI K412
T455-p
RMDPRAQtPVPGkGP
0 1
ARHGEF2 (human) RMDPRAQtPVPGkGP T455-p
ARHGEF2 iso2 (human) RMDPRAQTPVPGKGP T454
ARHGEF2 iso3 (human) RMDPRAQTPVPGKGP T427
ARHGEF2 (mouse) RMDPRAQTPVPGKGP T456
ARHGEF2 (rat) RMDPRAQTPVPGKGP T456
ARHGEF2 (pig) RMDPRAQTPVPGKGP T429
K460-ub
AQtPVPGkGPFGREE
0 2
ARHGEF2 (human) AQtPVPGkGPFGREE K460-ub
ARHGEF2 iso2 (human) AQTPVPGKGPFGREE K459
ARHGEF2 iso3 (human) AQTPVPGKGPFGREE K432
ARHGEF2 (mouse) AQTPVPGKGPFGRDE K461
ARHGEF2 (rat) AQTPVPGKGPFGRDE K461
ARHGEF2 (pig) AQTPVPGKGPFGREE K434
K472-ub
REELLRRkLIHDGCL
0 3
ARHGEF2 (human) REELLRRkLIHDGCL K472-ub
ARHGEF2 iso2 (human) REELLRRKLIHDGCL K471
ARHGEF2 iso3 (human) REELLRRKLIHDGCL K444
ARHGEF2 (mouse) RDELLRRKLIHEGCL K473
ARHGEF2 (rat) RDELLRRkLIHDGCL K473-ub
ARHGEF2 (pig) REELLRRKLIHDGCL K446
K482-ac
HDGCLLWkTATGRFK
0 2
ARHGEF2 (human) HDGCLLWkTATGRFK K482-ac
ARHGEF2 iso2 (human) HDGCLLWKTATGRFK K481
ARHGEF2 iso3 (human) HDGCLLWKTATGRFK K454
ARHGEF2 (mouse) HEGCLLWKTATGRFK K483
ARHGEF2 (rat) HDGCLLWKTATGRFK K483
ARHGEF2 (pig) HDGCLLWKTAAGRFK K456
K482-ub
HDGCLLWkTATGRFK
0 2
ARHGEF2 (human) HDGCLLWkTATGRFK K482-ub
ARHGEF2 iso2 (human) HDGCLLWKTATGRFK K481
ARHGEF2 iso3 (human) HDGCLLWKTATGRFK K454
ARHGEF2 (mouse) HEGCLLWKTATGRFK K483
ARHGEF2 (rat) HDGCLLWkTATGRFK K483-ub
ARHGEF2 (pig) HDGCLLWKTAAGRFK K456
K509-ub
FLQEKDQkyIFPTLD
0 1
ARHGEF2 (human) FLQEKDQkyIFPTLD K509-ub
ARHGEF2 iso2 (human) FLQEKDQKYIFPTLD K508
ARHGEF2 iso3 (human) FLQEKDQKYIFPTLD K481
ARHGEF2 (mouse) FLQEKDQKYIFTSLD K510
ARHGEF2 (rat) FLQEKDQKYIFTSLD K510
ARHGEF2 (pig) FLQEKDQKYIFPALD K483
Y510-p
LQEKDQkyIFPTLDk
0 2
ARHGEF2 (human) LQEKDQkyIFPTLDk Y510-p
ARHGEF2 iso2 (human) LQEKDQKYIFPTLDK Y509
ARHGEF2 iso3 (human) LQEKDQKYIFPTLDK Y482
ARHGEF2 (mouse) LQEKDQKYIFTSLDK Y511
ARHGEF2 (rat) LQEKDQKYIFTSLDk Y511
ARHGEF2 (pig) LQEKDQKYIFPALDK Y484
K517-ub
yIFPTLDkPsVVsLQ
0 4
ARHGEF2 (human) yIFPTLDkPsVVsLQ K517-ub
ARHGEF2 iso2 (human) YIFPTLDKPSVVSLQ K516
ARHGEF2 iso3 (human) YIFPTLDKPSVVSLQ K489
ARHGEF2 (mouse) YIFTSLDKPSVVSLQ K518
ARHGEF2 (rat) YIFTSLDkPSVVSLQ K518-ub
ARHGEF2 (pig) YIFPALDKPSVVSLQ K491
S519-p
FPTLDkPsVVsLQNL
0 1
ARHGEF2 (human) FPTLDkPsVVsLQNL S519-p
ARHGEF2 iso2 (human) FPTLDKPSVVSLQNL S518
ARHGEF2 iso3 (human) FPTLDKPSVVSLQNL S491
ARHGEF2 (mouse) FTSLDKPSVVSLQNL S520
ARHGEF2 (rat) FTSLDkPSVVSLQNL S520
ARHGEF2 (pig) FPALDKPSVVSLQNL S493
S522-p
LDkPsVVsLQNLIVR
0 2
ARHGEF2 (human) LDkPsVVsLQNLIVR S522-p
ARHGEF2 iso2 (human) LDKPSVVSLQNLIVR S521
ARHGEF2 iso3 (human) LDKPSVVSLQNLIVR S494
ARHGEF2 (mouse) LDKPSVVSLQNLIVR S523
ARHGEF2 (rat) LDkPSVVSLQNLIVR S523
ARHGEF2 (pig) LDKPSVVSLQNLIVR S496
K594-ub
EAYLRRIkMELQQkD
0 3
ARHGEF2 (human) EAYLRRIkMELQQkD K594-ub
ARHGEF2 iso2 (human) EAYLRRIKMELQQKD K593
ARHGEF2 iso3 (human) EAYLRRIKMELQQKD K566
ARHGEF2 (mouse) KAYLRRIKTKLQQKN K595
ARHGEF2 (rat) KAYLRRIKTKLQQKN K595
ARHGEF2 (pig) EAYLRRIKMELQQKD K568
K600-ub
IkMELQQkDRALVEL
0 3
ARHGEF2 (human) IkMELQQkDRALVEL K600-ub
ARHGEF2 iso2 (human) IKMELQQKDRALVEL K599
ARHGEF2 iso3 (human) IKMELQQKDRALVEL K572
ARHGEF2 (mouse) IKTKLQQKNQALVEL K601
ARHGEF2 (rat) IKTKLQQKNQALVEL K601
ARHGEF2 (pig) IKMELQQKDRALVEL K574
D626-ca
THFQAEEdGGSGMAL
0 1
ARHGEF2 (human) THFQAEEdGGSGMAL D626-ca
ARHGEF2 iso2 (human) THFQAEEDGGSGMAL D625
ARHGEF2 iso3 (human) THFQAEEDGGSGMAL D598
ARHGEF2 (mouse) VHFQALKAGFVGMPP A627
ARHGEF2 (rat) VHFQALKAGFIGMPP A627
ARHGEF2 (pig) THFQVEEDGGGGMPL D600
S643-p
LPRGLFRsEsLEsPR
0 5
ARHGEF2 (human) LPRGLFRsEsLEsPR S643-p
ARHGEF2 iso2 (human) LPRGLFRSESLESPR S642
ARHGEF2 iso3 (human) LPRGLFRSESLESPR S615
ARHGEF2 (mouse) LPRGLFRLEsFEsLR L644
ARHGEF2 (rat) LPRGLFRLEsFESLR L644
ARHGEF2 (pig) LPRGLFRSESLESPR S617
S645-p
RGLFRsEsLEsPRGE
Upstream
0 115
Treatment
  • dasatinib
  • ischemia
  • ZK-Thiazolidinone
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ARHGEF2 (human) RGLFRsEsLEsPRGE S645-p
ARHGEF2 iso2 (human) RGLFRSESLESPRGE S644
ARHGEF2 iso3 (human) RGLFRSESLESPRGE S617
ARHGEF2 (mouse) RGLFRLEsFEsLRGE S646-p
ARHGEF2 (rat) RGLFRLEsFESLRGE S646-p
ARHGEF2 (pig) RGLFRSESLESPRGE S619
S648-p
FRsEsLEsPRGERLL
0 12
ARHGEF2 (human) FRsEsLEsPRGERLL S648-p
ARHGEF2 iso2 (human) FRSESLESPRGERLL S647
ARHGEF2 iso3 (human) FRSESLESPRGERLL S620
ARHGEF2 (mouse) FRLEsFEsLRGERLL S649-p
ARHGEF2 (rat) FRLEsFESLRGERLL S649
ARHGEF2 (pig) FRSESLESPRGERLL S622
K666-ub
IREVEGLkDLLVGPG
0 7
ARHGEF2 (human) IREVEGLkDLLVGPG K666-ub
ARHGEF2 iso2 (human) IREVEGLKDLLVGPG K665
ARHGEF2 iso3 (human) IREVEGLKDLLVGPG K638
ARHGEF2 (mouse) LREVEGLKDLLLGPC K667
ARHGEF2 (rat) LREVEGLKDLLLGPC K667
ARHGEF2 (pig) IREVEGLKDLLVGPG K640
T679-p
PGVELLLtPREPALP
Upstream
Downstream
4 37
Effects on Modified Protein
  • activity, induced
  • molecular association, regulation
Effects on Biological Processes:
  • cytoskeletal reorganization
Putative in vivo kinases:
  • ERK1 (human)
  • ERK2 (human)
Treatment
  • anti-CD3
  • ischemia
  • PD184352
  • phorbol_ester
  • TNF
  • U0126
view more >
ARHGEF2 (human) PGVELLLtPREPALP T679-p
ARHGEF2 iso2 (human) PGVELLLtPREPALP T678-p
ARHGEF2 iso3 (human) PGVELLLTPREPALP T651
ARHGEF2 (mouse) PCVDLPMTSREPALP T680
ARHGEF2 (rat) PCVDLPLTAREPALP T680
ARHGEF2 (pig) PGVELLLtSREPALP T653-p
S691-p
ALPLEPDsGGNtsPG
Upstream
0 6
Treatment
  • BI2536
ARHGEF2 (human) ALPLEPDsGGNtsPG S691-p
ARHGEF2 iso2 (human) ALPLEPDSGGNTsPG S690
ARHGEF2 iso3 (human) ALPLEPDSGGNTSPG S663
ARHGEF2 (mouse) ALPLDSDSGSCPGVT S692
ARHGEF2 (rat) ALPVEADSGSCPGVT S692
ARHGEF2 (pig) ALPVETDSGGNTSPG S665
T695-p