Other Species / Isoforms
  CD3Z (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
K54
TALFLRVKFSRsADA
1 0
CD3Z (human) TALFLRVKFSRsADA K54
CD3Z iso3 (human) TALFLRVKFSRSADA K54
CD3Z (mouse) TALYLRAkFSRSAET K54-ub
CD3Z iso2 (mouse) TALYLRAKFSRSAET K54
CD3Z (rat) TALYLRAKFSRSADA K54
S58-p
LRVKFSRsADAPAyQ
0 6
CD3Z (human) LRVKFSRsADAPAyQ S58-p
CD3Z iso3 (human) LRVKFSRSADAPAYQ S58
CD3Z (mouse) LRAkFSRSAETAANL S58
CD3Z iso2 (mouse) LRAKFSRSAETAANL S58
CD3Z (rat) LRAKFSRSADAAAYL S58
Y64-p
RsADAPAyQQGQNQL
0 331
CD3Z (human) RsADAPAyQQGQNQL Y64-p
CD3Z iso3 (human) RSADAPAYQQGQNQL Y64
CD3Z (mouse) RSAETAANLQDPNQL N64
CD3Z iso2 (mouse) RSAETAANLQDPNQL N64
CD3Z (rat) RSADAAAYLQDPNQL Y64
Y72-p
QQGQNQLyNELNLGR
Upstream
Downstream
3 370
Effects on Modified Protein
  • phosphorylation
Treatment
  • anti-CD28
  • anti-CD3
  • U0126
  • vanadate
CD3Z (human) QQGQNQLyNELNLGR Y72-p
CD3Z iso3 (human) QQGQNQLYNELNLGR Y72
CD3Z (mouse) LQDPNQLyNELNLGR Y72-p
CD3Z iso2 (mouse) LQDPNQLYNELNLGR Y72
CD3Z (rat) LQDPNQLYNELNLGR Y72
Y83-p
NLGRREEyDVLDkRR
Upstream
Downstream
3 277
Effects on Biological Processes:
  • carcinogenesis, inhibited
  • signaling pathway regulation
Treatment
  • anti-CD28
  • anti-CD3
  • CXCL12
  • U0126
CD3Z (human) NLGRREEyDVLDkRR Y83-p
CD3Z iso3 (human) NLGRREEYDVLDKRR Y83
CD3Z (mouse) NLGRREEyDVLEKKR Y83-p
CD3Z iso2 (mouse) NLGRREEYDVLEKKR Y83
CD3Z (rat) NLGRREEYDVLDKKR Y83
K88-ub
EEyDVLDkRRGRDPE
0 4
CD3Z (human) EEyDVLDkRRGRDPE K88-ub
CD3Z iso3 (human) EEYDVLDKRRGRDPE K88
CD3Z (mouse) EEyDVLEKKRARDPE K88
CD3Z iso2 (mouse) EEYDVLEKKRARDPE K88
CD3Z (rat) EEYDVLDKKRPRDPE K88
K99-ub
RDPEMGGkPQRRkNP
0 4
CD3Z (human) RDPEMGGkPQRRkNP K99-ub
CD3Z iso3 (human) RDPEMGGkPRRKNPQ K99-ub
CD3Z (mouse) RDPEMGGkQQRRRNP K99-ub
CD3Z iso2 (mouse) RDPEMGGKQQRRRNP K99
CD3Z (rat) RDPEMGGKQQRRRNP K99
K104-ub
GGkPQRRkNPQEGLy
0 5
CD3Z (human) GGkPQRRkNPQEGLy K104-ub
CD3Z iso3 (human) MGGkPRRKNPQEGLy K103
CD3Z (mouse) GGkQQRRRNPQEGVy R104
CD3Z iso2 (mouse) GGKQQRRRNPQEGVY R104
CD3Z (rat) GGKQQRRRNPQEGVY R104
Y111-p
kNPQEGLyNELQkDk
Upstream
Downstream
3 407
Effects on Modified Protein
  • intracellular localization
Effects on Biological Processes:
  • carcinogenesis, inhibited
  • signaling pathway regulation
Regulatory protein:
  • Lck (human)
  • ZAP70 (human)
Treatment
  • anti-CD28
  • anti-CD3
  • U0126
  • vanadate
CD3Z (human) kNPQEGLyNELQkDk Y111-p
CD3Z iso3 (human) KNPQEGLyNELQKDK Y110-p
CD3Z (mouse) RNPQEGVyNALQKDK Y111-p
CD3Z iso2 (mouse) RNPQEGVYNALQKDK Y111
CD3Z (rat) RNPQEGVYNALQKDK Y111
K116-ub
GLyNELQkDkMAEAy
0 4
CD3Z (human) GLyNELQkDkMAEAy K116-ub
CD3Z iso3 (human) GLyNELQKDKMAEAY K115
CD3Z (mouse) GVyNALQKDKMAEAy K116
CD3Z iso2 (mouse) GVYNALQKDKMAEAY K116
CD3Z (rat) GVYNALQKDKMAEAy K116
K118-ub
yNELQkDkMAEAysE
0 4
CD3Z (human) yNELQkDkMAEAysE K118-ub
CD3Z iso3 (human) yNELQKDKMAEAYSE K117
CD3Z (mouse) yNALQKDKMAEAysE K118
CD3Z iso2 (mouse) YNALQKDKMAEAYSE K118
CD3Z (rat) YNALQKDKMAEAySE K118
Y123-p
kDkMAEAysEIGMkG
Upstream
Downstream
3 316
Effects on Modified Protein
  • intracellular localization
  • phosphorylation
Regulatory protein:
  • Lck (human)
Treatment
  • anti-CD28
  • anti-CD3
  • U0126
  • vanadate
CD3Z (human) kDkMAEAysEIGMkG Y123-p
CD3Z iso3 (human) KDKMAEAYSEIGMKG Y122
CD3Z (mouse) KDKMAEAysEIGTKG Y123-p
CD3Z iso2 (mouse) KDKMAEAYSEIGTKG Y123
CD3Z (rat) KDKMAEAySEIGMKG Y123-p
S124-p
DkMAEAysEIGMkGE
0 106
CD3Z (human) DkMAEAysEIGMkGE S124-p
CD3Z iso3 (human) DKMAEAYSEIGMKGE S123
CD3Z (mouse) DKMAEAysEIGTKGE S124-p
CD3Z iso2 (mouse) DKMAEAYSEIGTKGE S124
CD3Z (rat) DKMAEAySEIGMKGE S124
K129-ub
AysEIGMkGERRRGk
0 4
CD3Z (human) AysEIGMkGERRRGk K129-ub
CD3Z iso3 (human) AYSEIGMKGERRRGK K128
CD3Z (mouse) AysEIGTKGERRRGK K129
CD3Z iso2 (mouse) AYSEIGTKGERRRGK K129
CD3Z (rat) AySEIGMKGERRRGK K129
K136-ub
kGERRRGkGHDGLyQ
0 4
CD3Z (human) kGERRRGkGHDGLyQ K136-ub
CD3Z iso3 (human) KGERRRGKGHDGLYQ K135
CD3Z (mouse) KGERRRGKGHDGLyQ K136
CD3Z iso2 (mouse) KGERRRGKGHDGLYQ K136
CD3Z (rat) KGERRRGKGHDGLyQ K136
Y142-p
GkGHDGLyQGLstAt
Upstream
Downstream
9 421
CD3Z (human)
Y142-p
CD3Z iso3 (human)
Y141-p
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
  • phosphorylation
  • protein conformation
Effects on Biological Processes:
  • carcinogenesis, inhibited
  • signaling pathway regulation
Kinase, in vitro:
  • Lck (human)
Regulatory protein:
  • CD28 (human)
  • CD3Z (human)
  • TNFRSF9 (human)
  • ZAP70 (human)
Treatment
  • anti-CD28
  • anti-CD3
  • U0126
CD3Z (human) GkGHDGLyQGLstAt Y142-p
CD3Z iso3 (human) GKGHDGLYQGLSTAT Y141
CD3Z (mouse) GKGHDGLyQGLsTAT Y142-p
CD3Z iso2 (mouse) GKGHDGLYQDSHFQA Y142
CD3Z (rat) GKGHDGLyQGLSTAT Y142-p
S146-p
DGLyQGLstAtkDty
0 119
CD3Z (human) DGLyQGLstAtkDty S146-p
CD3Z iso3 (human) DGLYQGLSTATKDTY S145
CD3Z (mouse) DGLyQGLsTATKDty S146-p
CD3Z iso2 (mouse) gap -
CD3Z (rat) DGLyQGLSTATKDTY S146
T147-p
GLyQGLstAtkDtyD
0 31
CD3Z (human) GLyQGLstAtkDtyD T147-p
CD3Z iso3 (human) GLYQGLSTATKDTYD T146
CD3Z (mouse) GLyQGLsTATKDtyD T147
CD3Z iso2 (mouse) gap -
CD3Z (rat) GLyQGLSTATKDTYD T147
T149-p
yQGLstAtkDtyDAL
0 85
CD3Z (human) yQGLstAtkDtyDAL T149-p
CD3Z iso3 (human) YQGLSTATKDTYDAL T148
CD3Z (mouse) yQGLsTATKDtyDAL T149
CD3Z iso2 (mouse) gap -
CD3Z (rat) yQGLSTATKDTYDAL T149
K150-ub
QGLstAtkDtyDALH
0 2
CD3Z (human) QGLstAtkDtyDALH K150-ub
CD3Z iso3 (human) QGLSTATKDTYDALH K149
CD3Z (mouse) QGLsTATKDtyDALH K150
CD3Z iso2 (mouse) under review -
CD3Z (rat) QGLSTATKDTYDALH K150
T152-p
LstAtkDtyDALHMQ
0 100
CD3Z (human) LstAtkDtyDALHMQ T152-p
CD3Z iso3 (human) LSTATKDTYDALHMQ T151
CD3Z (mouse) LsTATKDtyDALHMQ T152-p
CD3Z iso2 (mouse) gap -
CD3Z (rat) LSTATKDTYDALHMQ T152
Y153-p
stAtkDtyDALHMQA
Upstream
Downstream
2 262
Effects on Modified Protein
  • molecular association, regulation
Regulatory protein:
  • ZAP70 (human)
Treatment
  • anti-CD28
  • anti-CD3
  • U0126
CD3Z (human) stAtkDtyDALHMQA Y153-p
CD3Z iso3 (human) STATKDTYDALHMQA Y152
CD3Z (mouse) sTATKDtyDALHMQT Y153-p
CD3Z iso2 (mouse) gap -
CD3Z (rat) STATKDTYDALHMQT Y153