Other Species / Isoforms
  TFAM (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

  HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
K52-ac
VLASCPKkPVssYLR
Downstream
0 1
Effects on Biological Processes:
  • transcription, induced
TFAM (human) VLASCPKkPVssYLR K52-ac
TFAM (mouse) SMGSYPKKPMSSYLR K51
TFAM (rat) SLGNYPKKPMSSYLR K51
K52-ub
VLASCPKkPVssYLR
0 1
TFAM (human) VLASCPKkPVssYLR K52-ub
TFAM (mouse) SMGSYPKKPMSSYLR K51
TFAM (rat) SLGNYPKKPMSSYLR K51
S55-p
SCPKkPVssYLRFsk
Upstream
Downstream
1 2
Effects on Modified Protein
  • intracellular localization
  • protein degradation
Effects on Biological Processes:
  • transcription, inhibited
Kinase, in vitro:
  • PKACA (human)
Putative in vivo kinases:
  • PKACA (human)
Treatment
  • H-89
  • KT5720
TFAM (human) SCPKkPVssYLRFsk S55-p
TFAM (mouse) SYPKKPMSSYLRFST S54
TFAM (rat) NYPKKPMSSYLRFST S54
S56-p
CPKkPVssYLRFskE
Upstream
1 1
Kinase, in vitro:
  • PKACA (human)
TFAM (human) CPKkPVssYLRFskE S56-p
TFAM (mouse) YPKKPMSSYLRFSTE S55
TFAM (rat) YPKKPMSSYLRFSTE S55
S61-p
VssYLRFskEQLPIF
Upstream
Downstream
1 2
Effects on Biological Processes:
  • transcription, induced
Kinase, in vitro:
  • PKACA (human)
TFAM (human) VssYLRFskEQLPIF S61-p
TFAM (mouse) MSSYLRFSTEQLPKF S60
TFAM (rat) MSSYLRFSTEQLPKF S60
K62-ub
ssYLRFskEQLPIFk
0 1
TFAM (human) ssYLRFskEQLPIFk K62-ub
TFAM (mouse) SSYLRFSTEQLPKFK T61
TFAM (rat) SSYLRFSTEQLPKFK T61
K69-ac
kEQLPIFkAQNPDAk
Downstream
0 1
Effects on Biological Processes:
  • transcription, induced
TFAM (human) kEQLPIFkAQNPDAk K69-ac
TFAM (mouse) TEQLPKFKAKHPDAK K68
TFAM (rat) TEQLPKFKAKHPDAK K68
K69-m1
kEQLPIFkAQNPDAk
0 1
TFAM (human) kEQLPIFkAQNPDAk K69-m1
TFAM (mouse) TEQLPKFKAKHPDAK K68
TFAM (rat) TEQLPKFKAKHPDAK K68
K76-ac
kAQNPDAkTTELIrR
Downstream
1 0
Effects on Modified Protein
  • molecular association, regulation
TFAM (human) kAQNPDAkTTELIrR K76-ac
TFAM (mouse) KAKHPDAKLSELVRK K75
TFAM (rat) KAKHPDAKVSELIRK K75
K76-ub
kAQNPDAkTTELIrR
0 4
TFAM (human) kAQNPDAkTTELIrR K76-ub
TFAM (mouse) KAKHPDAKLSELVRK K75
TFAM (rat) KAKHPDAKVSELIRK K75
R82-m1
AkTTELIrRIAQRWR
0 1
TFAM (human) AkTTELIrRIAQRWR R82-m1
TFAM (mouse) AKLSELVRKIAALWR R81
TFAM (rat) AKVSELIRKIAAMWR R81
K95-sc
WRELPDSkKKIyQDA
0 1
TFAM (human) WRELPDSkKKIyQDA K95-sc
TFAM (mouse) WRELPEAEKKVYEAD E94
TFAM (rat) WRELPEAEKKVYEAD E94
Y99-p
PDSkKKIyQDAYRAE
0 2
TFAM (human) PDSkKKIyQDAYRAE Y99-p
TFAM (mouse) PEAEKKVYEADFKAE Y98
TFAM (rat) PEAEKKVYEADFKAE Y98
K111-ac
RAEWQVYkEEISRFk
0 1
TFAM (human) RAEWQVYkEEISRFk K111-ac
TFAM (mouse) KAEWKAYKEAVSKYK K110
TFAM (rat) KAEWKVYKEAVSKYK K110
K111-ub
RAEWQVYkEEISRFk
0 1
TFAM (human) RAEWQVYkEEISRFk K111-ub
TFAM (mouse) KAEWKAYKEAVSKYK K110
TFAM (rat) KAEWKVYKEAVSKYK K110
K118-ub
kEEISRFkEQLtPsQ
0 3
TFAM (human) kEEISRFkEQLtPsQ K118-ub
TFAM (mouse) KEAVSKYKEQLTPSQ K117
TFAM (rat) KEAVSKYKEQLTPSQ K117
T122-p
SRFkEQLtPsQIMsL
Upstream
0 7
Treatment
  • AZD1152
  • MLN8054
  • ZM447439
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TFAM (human) SRFkEQLtPsQIMsL T122-p
TFAM (mouse) SKYKEQLTPSQLMGM T121
TFAM (rat) SKYKEQLTPSQLMGL T121
S124-p
FkEQLtPsQIMsLEK
0 11
TFAM (human) FkEQLtPsQIMsLEK S124-p
TFAM (mouse) YKEQLTPSQLMGMEK S123
TFAM (rat) YKEQLTPSQLMGLEK S123
S128-p
LtPsQIMsLEKEIMD
0 1
TFAM (human) LtPsQIMsLEKEIMD S128-p
TFAM (mouse) LTPSQLMGMEKEARQ G127
TFAM (rat) LTPSQLMGLEKEARQ G127
K146-m3
KRKAMTKkkELTLLG
0 1
TFAM (human) KRKAMTKkkELTLLG K146-m3
TFAM (mouse) KKKALVKRRELILLG R145
TFAM (rat) KKKAQIKRRELILLG R145
K147-m3
RKAMTKkkELTLLGk
0 1
TFAM (human) RKAMTKkkELTLLGk K147-m3
TFAM (mouse) KKALVKRRELILLGK R146
TFAM (rat) KKAQIKRRELILLGK R146
K154-ac
kELTLLGkPKRPRsA
Downstream
0 1
Effects on Biological Processes:
  • transcription, induced
TFAM (human) kELTLLGkPKRPRsA K154-ac
TFAM (mouse) RELILLGKPKRPRSA K153
TFAM (rat) RELILLGKPKRPRSA K153
S160-p
GkPKRPRsAYNVyVA
Upstream
1 1
Kinase, in vitro:
  • PKACA (human)
TFAM (human) GkPKRPRsAYNVyVA S160-p
TFAM (mouse) GKPKRPRSAYNIYVS S159
TFAM (rat) GKPKRPRSAYNIYVS S159
Y165-p
PRsAYNVyVAERFQE
0 1
TFAM (human) PRsAYNVyVAERFQE Y165-p
TFAM (mouse) PRSAYNIYVSESFQE Y164
TFAM (rat) PRSAYNIYVSESFQE Y164
S177-p
FQEAKGDsPQEKLKT
Upstream
Downstream
1 2
Effects on Modified Protein
  • molecular association, regulation
Effects on Biological Processes:
  • transcription, inhibited
Kinase, in vitro:
  • ERK2 (human)
Putative in vivo kinases:
  • ERK2 (human)
Treatment
  • U0126
TFAM (human) FQEAKGDsPQEKLKT S177-p
TFAM (mouse) FQEAKDDSAQGKLKL S176
TFAM (rat) FQEAKDESAQGKLKL S176
K186-ub
QEKLKTVkENWkNLs
0 1
TFAM (human) QEKLKTVkENWkNLs K186-ub
TFAM (mouse) QGKLKLVNEAWKNLS N185
TFAM (rat) QGKLKLVNQAWKNLS N185
K190-ub
KTVkENWkNLsDsEk
0 1
TFAM (human) KTVkENWkNLsDsEk K190-ub
TFAM (mouse) KLVNEAWKNLSPEEK K189
TFAM (rat) KLVNQAWKNLSHDEK K189
K190-sc
KTVkENWkNLsDsEk
0 1
TFAM (human) KTVkENWkNLsDsEk K190-sc
TFAM (mouse) KLVNEAWKNLSPEEK K189
TFAM (rat) KLVNQAWKNLSHDEK K189
S193-p
kENWkNLsDsEkELy
0 11
TFAM (human) kENWkNLsDsEkELy S193-p
TFAM (mouse) NEAWKNLSPEEKQAY S192
TFAM (rat) NQAWKNLSHDEKQAY S192
S195-p
NWkNLsDsEkELyIQ
0 7
TFAM (human) NWkNLsDsEkELyIQ S195-p
TFAM (mouse) AWKNLSPEEKQAYIQ E194
TFAM (rat) AWKNLSHDEKQAYIQ D194
K197-ac
kNLsDsEkELyIQHA
Downstream
0 1
Effects on Biological Processes:
  • transcription, induced
TFAM (human) kNLsDsEkELyIQHA K197-ac
TFAM (mouse) KNLSPEEKQAYIQLA K196
TFAM (rat) KNLSHDEKQAYIQLA K196
K197-ub
kNLsDsEkELyIQHA
0 1
TFAM (human) kNLsDsEkELyIQHA K197-ub
TFAM (mouse) KNLSPEEKQAYIQLA K196
TFAM (rat) KNLSHDEKQAYIQLA K196
Y200-p
sDsEkELyIQHAkED
0 1
TFAM (human) sDsEkELyIQHAkED Y200-p
TFAM (mouse) SPEEKQAYIQLAKDD Y199
TFAM (rat) SHDEKQAYIQLAKDD Y199
K205-sc
ELyIQHAkEDETRYH
0 1
TFAM (human) ELyIQHAkEDETRYH K205-sc
TFAM (mouse) QAYIQLAKDDRIRYD K204
TFAM (rat) QAYIQLAKDDRIRYD K204
E244
KQRKYGAEEC_____
0 3
TFAM (human) KQRKYGAEEC_____ E244
TFAM (mouse) VKRSGDIsEH_____ S241-p
TFAM (rat) KRPPGDISEN_____ S242