Other Species / Isoforms
  H2AX (mouse)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
K5-ac
___SGRGkTGGkARA
5 65
H2AX (human) ___SGRGkTGGkARA K5-ac
H2AX (mouse) ___SGRGkTGGkARA K5-ac
H2AX (rat) ___SGRGkTGGkARA K5-ac
K9-ac
GRGkTGGkARAKAKS
1 65
H2AX (human) GRGkTGGkARAkAks K9-ac
H2AX (mouse) GRGkTGGkARAKAKS K9-ac
H2AX (rat) GRGkTGGkARAKAKS K9-ac
K13
TGGkARAKAKSRSSR
2 0
H2AX (human) TGGkARAkAksRSSR K13-ub
H2AX (mouse) TGGkARAKAKSRSSR K13
H2AX (rat) TGGkARAKAKSRSSR K13
K15
GkARAKAKSRSSRAG
2 0
H2AX (human) GkARAkAksRSSRAG K15-ub
H2AX (mouse) GkARAKAKSRSSRAG K15
H2AX (rat) GkARAKAKSRSSRAG K15
S16
kARAKAKSRSSRAGL
1 0
H2AX (human) kARAkAksRSSRAGL S16-p
H2AX (mouse) kARAKAKSRSSRAGL S16
H2AX (rat) kARAKAKSRSSRAGL S16
K36
RVHRLLRKGHYAERV
2 1
H2AX (human) RVHRLLRkGHyAERV K36-ac
H2AX (mouse) RVHRLLRKGHYAERV K36
H2AX (rat) RVHRLLRKGHYAERV K36
Y39
RLLRKGHYAERVGAG
3 2
H2AX (human) RLLRkGHyAERVGAG Y39-p
H2AX (mouse) RLLRKGHYAERVGAG Y39
H2AX (rat) RLLRKGHYAERVGAG Y39
Y57
YLAAVLEYLTAEILE
1 1
H2AX (human) YLAAVLEyLTAEILE Y57-p
H2AX (mouse) YLAAVLEYLTAEILE Y57
H2AX (rat) YLAAVLEYLTAEILE Y57
K95-ub
RNDEELNkLLGGVTI
0 18
H2AX (human) RNDEELNkLLGGVtI K95-ub
H2AX (mouse) RNDEELNkLLGGVTI K95-ub
H2AX (rat) RNDEELNKLLGGVtI K95
T101
NkLLGGVTIAQGGVL
1 5
H2AX (human) NkLLGGVtIAQGGVL T101-p
H2AX (mouse) NkLLGGVTIAQGGVL T101
H2AX (rat) NKLLGGVtIAQGGVL T101-p
K118-ac
IQAVLLPkkSsATVG
0 43
H2AX (human) IQAVLLPkktsAtVG K118-ac
H2AX (mouse) IQAVLLPkkSsATVG K118-ac
H2AX (rat) IQAVLLPkkTsATVG K118-ac
K118-ub
IQAVLLPkkSsATVG
4 176
H2AX (human) IQAVLLPkktsAtVG K118-ub
H2AX (mouse) IQAVLLPkkSsATVG K118-ub
H2AX (rat) IQAVLLPkkTsATVG K118-ub
K119-ac
QAVLLPkkSsATVGP
0 19
H2AX (human) QAVLLPkktsAtVGP K119-ac
H2AX (mouse) QAVLLPkkSsATVGP K119-ac
H2AX (rat) QAVLLPkkTsATVGP K119-ac
K119-ub
QAVLLPkkSsATVGP
4 163
H2AX (human) QAVLLPkktsAtVGP K119-ub
H2AX (mouse) QAVLLPkkSsATVGP K119-ub
H2AX (rat) QAVLLPkkTsATVGP K119-ub
S120
AVLLPkkSsATVGPk
0 4
H2AX (human) AVLLPkktsAtVGPk T120-p
H2AX (mouse) AVLLPkkSsATVGPk S120
H2AX (rat) AVLLPkkTsATVGPk T120
S121-p
VLLPkkSsATVGPkA
0 6
H2AX (human) VLLPkktsAtVGPkA S121-p
H2AX (mouse) VLLPkkSsATVGPkA S121-p
H2AX (rat) VLLPkkTsATVGPkA S121-p
T123
LPkkSsATVGPkAPA
0 2
H2AX (human) LPkktsAtVGPkAPs T123-p
H2AX (mouse) LPkkSsATVGPkAPA T123
H2AX (rat) LPkkTsATVGPkAPA T123
K127-ac
SsATVGPkAPAVGkK
0 1
H2AX (human) tsAtVGPKAPsGGkk K127
H2AX (mouse) SsATVGPkAPAVGkK K127-ac
H2AX (rat) TsATVGPKAPAGGkk K127
K127-ub
SsATVGPkAPAVGkK
0 112
H2AX (human) tsAtVGPkAPsGGkk K127-ub
H2AX (mouse) SsATVGPkAPAVGkK K127-ub
H2AX (rat) TsATVGPkAPAGGkk K127-ub
A130
TVGPkAPAVGkKAsQ
0 2
H2AX (human) tVGPkAPsGGkkAtQ S130-p
H2AX (mouse) TVGPkAPAVGkKAsQ A130
H2AX (rat) TVGPkAPAGGkkAsQ A130
K133-ac
PkAPAVGkKAsQAsQ
0 6
H2AX (human) PkAPsGGkkAtQAsQ K133-ac
H2AX (mouse) PkAPAVGkKAsQAsQ K133-ac
H2AX (rat) PkAPAGGkkAsQAsQ K133-ac
K133
PkAPAVGKKAsQAsQ
0 5
H2AX (human) PkAPsGGkkAtQAsQ K133-ub
H2AX (mouse) PkAPAVGKKAsQAsQ K133
H2AX (rat) PkAPAGGKkAsQAsQ K133
K134
kAPAVGkKAsQAsQE
0 1
H2AX (human) kAPsGGkKAtQAsQE K134
H2AX (mouse) kAPAVGkKAsQAsQE K134
H2AX (rat) kAPAGGkkAsQAsQE K134-ac
K134
kAPAVGkKAsQAsQE
1 0
H2AX (human) kAPsGGkkAtQAsQE K134-m2
H2AX (mouse) kAPAVGkKAsQAsQE K134
H2AX (rat) kAPAGGkKAsQAsQE K134
K134
kAPAVGkKAsQAsQE
0 10
H2AX (human) kAPsGGkkAtQAsQE K134-ub
H2AX (mouse) kAPAVGkKAsQAsQE K134
H2AX (rat) kAPAGGkKAsQAsQE K134
K134
kAPAVGkKAsQAsQE
0 1
H2AX (human) kAPsGGkkAtQAsQE K134-sm
H2AX (mouse) kAPAVGkKAsQAsQE K134
H2AX (rat) kAPAGGkKAsQAsQE K134
S136-p
PAVGkKAsQAsQEy_
Upstream
5 20
Regulatory protein:
  • TSC2 (mouse)
Treatment
  • insulin
  • LY294002
  • MMS
H2AX (human) PsGGkkAtQAsQEy_ T136-p
H2AX (mouse) PAVGkKAsQAsQEy_ S136-p
H2AX (rat) PAGGkkAsQAsQEY_ S136-p
S139-p
GkKAsQAsQEy____
Upstream
Downstream
197 52
H2AX (human)
S139-p
H2AX (mouse)
S139-p
H2AX (rat)
S139-p
Effects on Modified Protein
  • activity, induced
  • molecular association, regulation
Effects on Biological Processes:
  • apoptosis, induced
Kinase, in vitro:
  • ATM (mouse)
  • JNK1 (mouse)
  • JNK2 (mouse)
Putative in vivo kinases:
  • ATM (mouse)
  • JNK1 (mouse)
  • JNK2 (mouse)
Putative upstream phosphatases:
  • PPM1D (mouse)
Regulatory protein:
  • ATM (mouse)
  • ATR (mouse)
  • DNAPK (mouse)
  • ERK2 (mouse)
  • HDAC2 (mouse)
  • HDAC3 (mouse)
  • JNK1 (mouse)
  • JNK2 (mouse)
  • MAPKAPK2 (mouse)
  • MDM4 (mouse)
  • P38B (mouse)
  • POT1 (mouse)
  • PTPN2 (human)
  • ROCK1 (human)
  • S6 (mouse)
  • SMO (mouse)
  • TOP3B (mouse)
  • TREX1 (mouse)
Treatment
  • adriamycin
  • aphidicolin
  • bleomycin
  • calyculin_A
  • camptothecin
  • cisplatin
  • etoposide
  • HA-1077
  • hydroxyurea
  • hypoxia
  • insulin
  • ionizing_radiation
  • KU-55933
  • low_pH
  • LY294002
  • neocarzinostatin
  • osmotic_stress
  • PD98059
  • SB202190
  • serum
  • siRNA
  • SP600125
  • tempol
  • thymidine
  • U0126
  • UV
  • VM-26
  • wortmannin
H2AX (human) GkkAtQAsQEy____ S139-p
H2AX (mouse) GkKAsQAsQEy____ S139-p
H2AX (rat) GkkAsQAsQEY____ S139-p
Y142-p
AsQAsQEy_______
6 3
H2AX (human)
Y142-p
H2AX (mouse)
Y142-p
H2AX (rat)
Y142-p
H2AX (human) AtQAsQEy_______ Y142-p
H2AX (mouse) AsQAsQEy_______ Y142-p
H2AX (rat) AsQAsQEY_______ Y142