Other Species / Isoforms
  p16-INK4A (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
A100
TLVVLHRAGARLDVR
0 1
p16-INK4A (human) TLVVLHRAGARLDVR A100
p16-INK4A iso3 (human) KFAGELEsGsASILR S76-p
p16-INK4A iso4 (human) TLVVLHRAGARLDVR A100
p16-INK4A (mouse) TLVVLHGSGARLDVR S92
p16-INK4A (rat) TLVVLHQAGARLDVR A92
S7-p
_MEPAAGssMEPSAD
Upstream
Downstream
3 0
Effects on Modified Protein
  • protein stabilization
Putative in vivo kinases:
  • ATR (human)
Treatment
  • siRNA
  • UV
p16-INK4A (human) _MEPAAGssMEPSAD S7-p
p16-INK4A iso3 (human) _MEPAAGSSMEPSAD S7
p16-INK4A iso4 (human) _MEPAAGSSMEPSAD S7
p16-INK4A (mouse) gap -
p16-INK4A (rat) gap -
R103
VLHRAGARLDVRDAW
0 4
p16-INK4A (human) VLHRAGARLDVRDAW R103
p16-INK4A iso3 (human) AGELEsGsASILRKK S78-p
p16-INK4A iso4 (human) VLHRAGARLDVRDAW R103
p16-INK4A (mouse) VLHGSGARLDVRDAW R95
p16-INK4A (rat) VLHQAGARLDVRDAW R95
S8-p
MEPAAGssMEPSADW
Upstream
Downstream
3 0
Effects on Modified Protein
  • activity, inhibited
  • protein stabilization
Kinase, in vitro:
  • IKKB (human)
Putative in vivo kinases:
  • ATR (human)
  • IKKB (human)
Treatment
  • siRNA
  • UV
p16-INK4A (human) MEPAAGssMEPSADW S8-p
p16-INK4A iso3 (human) MEPAAGSSMEPSADW S8
p16-INK4A iso4 (human) MEPAAGSSMEPSADW S8
p16-INK4A (mouse) gap -
p16-INK4A (rat) gap -
Y44-p
LPNAPNSyGRRPIQV
Upstream
0 1
Regulatory protein:
  • EGFR (human)
Treatment
  • EGF
p16-INK4A (human) LPNAPNSyGRRPIQV Y44-p
p16-INK4A iso3 (human) LPNAPNSYGRRPIQV Y44
p16-INK4A iso4 (human) LPNAPNSYGRRPIQV Y44
p16-INK4A (mouse) SPNAPNSFGRTPIQV F36
p16-INK4A (rat) SPNAPNTFGRTPIQV F36
R131-m1
RDVARYLrAAAGGTr
0 1
p16-INK4A (human) RDVARYLrAAAGGTr R131-m1
p16-INK4A iso3 (human) gap -
p16-INK4A iso4 (human) RDVARYLRAAAGGTR R131
p16-INK4A (mouse) QDIVRYLRSAGCSLC R123
p16-INK4A (rat) HDVVRYLRYLLSSAG R123
R138-me
rAAAGGTrGsNHARI
Downstream
1 0
Effects on Biological Processes:
  • apoptosis, inhibited
  • cell growth, induced
p16-INK4A (human) rAAAGGTrGsNHARI R138-me
p16-INK4A iso3 (human) gap -
p16-INK4A iso4 (human) RAAAGGTRGSNHARI R138
p16-INK4A (mouse) RSAGCSLCSAGWSLC C130
p16-INK4A (rat) gap -
S140-p
AAGGTrGsNHARIDA
Upstream
Downstream
4 0
Effects on Modified Protein
  • molecular association, regulation
  • protein stabilization
Effects on Biological Processes:
  • apoptosis, induced
  • cell growth, inhibited
Putative in vivo kinases:
  • ATR (human)
Treatment
  • H2O2
  • siRNA
  • UV
p16-INK4A (human) AAGGTrGsNHARIDA S140-p
p16-INK4A iso3 (human) gap -
p16-INK4A iso4 (human) AAGGTRGSNHARIDA S140
p16-INK4A (mouse) gap -
p16-INK4A (rat) gap -
S152-p
IDAAEGPsDIPD___
Upstream
Downstream
3 1
Effects on Modified Protein
  • molecular association, regulation
  • protein stabilization
Putative in vivo kinases:
  • ATR (human)
Treatment
  • siRNA
  • UV
p16-INK4A (human) IDAAEGPsDIPD___ S152-p
p16-INK4A iso3 (human) gap -
p16-INK4A iso4 (human) IDAAEGPSEMIGNHL S152
p16-INK4A (mouse) gap -
p16-INK4A (rat) LSSAGNVSRVTDRHN S133
-
gap
0 1
p16-INK4A (human) gap -
p16-INK4A iso3 (human) gap -
p16-INK4A iso4 (human) NHLWVCRSRHA____ S164
p16-INK4A (mouse) ALELRGQsQEQs___ S164-p
p16-INK4A (rat) gap -
-
gap
0 1
p16-INK4A (human) gap -
p16-INK4A iso3 (human) gap -
p16-INK4A iso4 (human) gap -
p16-INK4A (mouse) RGQsQEQs_______ S168-p
p16-INK4A (rat) gap -